Digital Commons Network^™

Comparison Of Seasonal Foes And Fbes Occurrence Rates Derived From Global Digisonde Measurements, Dawn K. Merriman, Omar A. Nava, Eugene V. Dao, Daniel J. Emmons Ii

Faculty Publications

A global climatology of sporadic-E occurrence rates (ORs) based on ionosonde measurements is presented for the peak blanketing frequency, fbEs, and the ordinary mode peak frequency of the layer, foEs. ORs are calculated for a variety of sporadic-E frequency thresholds: no lower limit, 3, 5, and 7 MHz. Seasonal rates are calculated from 64 Digisonde sites during the period 2006–2020 using ionograms either manually or automatically scaled with ARTIST-5. Both foEs and fbEs ORs peak in the Northern Hemisphere during the boreal summer, with a decrease by roughly a factor of 2–3 in fbEs rates relative to foEs rates without …

A Staged Approach To Address Youth Unresponsive To Initial Obesity Intervention: A Randomized Clinical Trial, Katherine R Arlinghaus, Daniel P O'Connor, Tracey A Ledoux, Sheryl O Hughes, Craig A Johnston

Children’s Nutrition Research Center Staff Publications

Background/objective: Maintenance interventions inherently require BMI improvement to maintain. This overlooks individuals initially unresponsive to obesity interventions. Staged pediatric clinical treatment guidelines were adapted to the school setting to develop an escalated treatment option for individuals initially unresponsive. This staged randomized controlled trial examined differences between escalated treatment (Take CHARGE!) and a maintenance program (PE Planners). Take CHARGE was hypothesized to have greater improvements in BMI as a percentage of the 95th BMI Percentile (%BMIp95) than PE Planners.

Subjects/methods: From 2018 to 2020, 171 middle and high schoolers (BMI Percentile ≥ 85) were recruited from a Houston school district to …

5-Ht Recruits Distinct Neurocircuits To Inhibit Hunger-Driven And Non-Hunger-Driven Feeding, Yanlin He, Xing Cai, Hailan Liu, Krisitine M Conde, Pingwen Xu, Yongxiang Li, Chunmei Wang, Meng Yu, Yang He, Hesong Liu, Chen Liang, Tingting Yang, Yongjie Yang, Kaifan Yu, Julia Wang, Rong Zheng, Feng Liu, Zheng Sun, Lora Heisler, Qi Wu, Qingchun Tong, Canjun Zhu, Gang Shu, Yong Xu

Children’s Nutrition Research Center Staff Publications

Obesity is primarily a consequence of consuming calories beyond energetic requirements, but underpinning drivers have not been fully defined. 5-Hydroxytryptamine (5-HT) neurons in the dorsal Raphe nucleus (5-HTDRN) regulate different types of feeding behavior, such as eating to cope with hunger or for pleasure. Here, we observed that activation of 5-HTDRN to hypothalamic arcuate nucleus (5-HTDRN → ARH) projections inhibits food intake driven by hunger via actions at ARH 5-HT2C and 5-HT1B receptors, whereas activation of 5-HTDRN to ventral tegmental area (5-HTDRN → VTA) projections inhibits non-hunger-driven feeding via actions at 5-HT2C receptors. Further, hunger-driven feeding gradually activates ARH-projecting 5-HTDRN …

Dash Diet Adherence And Cognitive Function: Multi-Ethnic Study Of Atherosclerosis, George D Daniel, Haiying Chen, Alain G Bertoni, Stephen R Rapp, Annette L Fitzpatrick, José A Luchsinger, Alexis C Wood, Timothy M Hughes, Gregory L Burke, Kathleen M Hayden

Children’s Nutrition Research Center Staff Publications

Background and aims: The Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet has been associated with better cognitive function in studies of predominantly White participants; few studies have examined this association in diverse cohorts. Our objective was to examine the association between the DASH diet and cognitive function in the diverse Multi-Ethnic Study of Atherosclerosis (MESA) cohort.

Methods: Among 4169 MESA participants, we evaluated prospectively, the association between DASH diet adherence and cognitive function. Participants completed a food frequency questionnaire at baseline (2000-2002) and cognitive function was assessed using the Cognitive Abilities Screening Instrument (CASI), Digit Symbol Coding …

Intermittent Bolus Feeding Does Not Enhance Protein Synthesis, Myonuclear Accretion, Or Lean Growth More Than Continuous Feeding In A Premature Piglet Model, Marko Rudar, Jane K Naberhuis, Agus Suryawan, Hanh V Nguyen, Barbara Stoll, Candace C Style, Mariatu A Verla, Oluyinka O Olutoye, Douglas G Burrin, Marta L Fiorotto, Teresa A Davis

Children’s Nutrition Research Center Staff Publications

Optimizing enteral nutrition for premature infants may help mitigate extrauterine growth restriction and adverse chronic health outcomes. Previously, we showed in neonatal pigs born at term that lean growth is enhanced by intermittent bolus compared with continuous feeding. The objective was to determine if prematurity impacts how body composition, muscle protein synthesis, and myonuclear accretion respond to feeding modality. Following preterm delivery, pigs were fed equivalent amounts of formula delivered either as intermittent boluses (INT; n = 30) or continuously (CONT; n = 14) for 21 days. Body composition was measured by dual-energy X-ray absorptiometry (DXA) and muscle growth was …

Poultry Producer's Willingness To Invest In On-Farm Carcass Disposal, V. L. Campbell, J. M. Thompson, J. L. Apriesnig, D. L. Pendell, G. T. Tonsor

Michigan Tech Publications, Part 1

Foreign animal diseases (FAD) can cause substantial economic losses in production, consumption, and the supply chain. These diseases are typically highly pathogenic and lead to disruptions in normal business practices and to demands for higher investment in biosecurity practices. For poultry producers this can lead to changes in bird pick-ups, chick placements, and length of out time on farms as well as changes in day-to-day operations. When an FAD is reported, poultry producers that rely on off-premises carcass disposal (e.g., renderers or landfills) may be required to develop on-farm disposal capacity (e.g., incinerators or burial) rapidly if their operation falls …

Lasting Consequences Of Psyllid (Bactericera Cockerelli L.) Infestation On Tomato Defense, Gene Expression, And Growth, Kyle Harrison, Azucena Mendoza-Herrera, Julien Gad Levy, Cecilia Tamborindeguy

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: The tomato psyllid, Bactericera cockerelli Šulc (Hemiptera: Triozidae), is a pest of solanaceous crops such as tomato (Solanum lycopersicum L.) in the U.S. and vectors the disease-causing pathogen ‘Candidatus Liberibacter solanacearum’. Currently, the only effective strategies for controlling the diseases associated with this pathogen involve regular pesticide applications to manage psyllid population density. However, such practices are unsustainable and will eventually lead to widespread pesticide resistance in psyllids. Therefore, new control strategies must be developed to increase host-plant resistance to insect vectors. For example, expression of constitutive and inducible plant defenses can be improved through selection. Currently, it is …

La Fille Publique: Depictions Of Sex Work In Fin-De-Siècle Literature, Nicole Araujo

All Student Scholarship

This thesis conducts a feminist analysis of depictions of sex work in fin-de-siècle, or turn of the19th-century, French literature. It draws connections between literature from this time period and the social and political forces that sought to eradicate female sexual autonomy. In the introduction, the political and social setting of fin-de-siècle France is explored, when sex work was widely prevalent and for many women offered a route to sexual and financial autonomy that was otherwise unattainable, much to the anxiety and irritation of the patriarchal forces in place.The first chapter analyzes Emile Zola’s Nana as a classic representation of the …

On Preserving The Behavior In Software Refactoring: A Systematic Mapping Study, Eman Abdullah Alomar, Mohamed Wiem Mkaouer, Christian D. Newman, Ali Ouni

Articles

Context: Refactoring is the art of modifying the design of a system without altering its behavior. The idea is to reorganize variables, classes and methods to facilitate their future adaptations and comprehension. As the concept of behavior preservation is fundamental for refactoring, several studies, using formal verification, language transformation and dynamic analysis, have been proposed to monitor the execution of refactoring operations and their impact on the program semantics. However, there is no existing study that examines the available behavior preservation strategies for each refactoring operation.

Objective: This paper identifies behavior preservation approaches in the research literature. Method: We conduct, …

Exploring Teachers’ Perceptions Of Assessment Literacy In A High Performing School District In New Jersey, Marlena Celebre-Baird

Seton Hall University Dissertations and Theses (ETDs)

As teachers gain experience, their assessment knowledge base, personal beliefs, and the educational context come together to shape their identity as an assessor. Therefore, assessment literacy is not simply a stagnant knowledge base of skills but rather that takes shape over time, through reflective teaching continues to develop. This study sought to add to the body of research that highlights and describes, through the lens of the teacher, how beliefs and contextual factors influence a teachers’ assessment literacy in practice.

A qualitative case study methodology was selected for this study to explore how elementary K–5 teachers’ personal beliefs play a …

Examining Neocolonialism In International Branch Campuses In China: A Case Study Of Mimicry

Journal of Comparative & International Higher Education

No abstract provided.

Jcihe: Winter 2020: Special Issue Introduction And State Of The Field 2021

Journal of Comparative & International Higher Education

No abstract provided.

Understanding The Attraction Of The Microcampus: A Quantitative Investigation Of Students’ Motivations To Enroll In Transnational Education

Journal of Comparative & International Higher Education

No abstract provided.

Conolidine: A Novel Plant Extract For Chronic Pain, Amber N. Edinoff, Akash S. Patel, Mitchell W. Baker, Jesse Lawson, Christopher Wolcott, Elyse M. Cornett, Kambiz Sadegi, Adam M. Kaye, Alan David Kaye

School of Pharmacy Faculty Articles

Pain, the most common symptom reported among patients in the primary care setting, is complex to manage. Opioids are among the most potent analgesics agents for managing pain. Since the mid-1990s, the number of opioid prescriptions for the management of chronic non-cancer pain (CNCP) has increased by more than 400%, and this increased availability has significantly contributed to opioid diversion, overdose, tolerance, dependence, and addiction. Despite the questionable effectiveness of opioids in managing CNCP and their high rates of side effects, the absence of available alternative medications and their clinical limitations and slower onset of action has led to an …

Mif But Not Mif-2 Recruits Inflammatory Macrophages In An Experimental Polymicrobial Sepsis Model, Pathricia Veronica Tilstam, Wibke Schulte, Thomas Holowka, Bong-Sung Kim, Jessica Nouws, Maor Sauler, Marta Piecychna, Georgios Pantouris, Elias Lolis, Lin Leng, Jürgen Bernhagen, Günter Fingerle-Rowson, Richard Bucala

Pacific Faculty Work

Excessive inflammation drives the progression from sepsis to septic shock. Macrophage migration inhibitory factor (MIF) is of interest because MIF promoter polymorphisms predict mortality in different infections, and anti-MIF antibody improves survival in experimental models when administered 8 hours after infectious insult. The recent description of a second MIF superfamily member, D-dopachrome tautomerase (D-DT/MIF-2), prompted closer investigation of MIF-dependent responses. We subjected Mif^-/- and Mif-2^-/- mice to polymicrobial sepsis and observed a survival benefit with Mif but not Mif-2 deficiency. Survival was associated with reduced numbers of small peritoneal macrophages (SPMs) that, in contrast to large peritoneal macrophages …

Identification Of Disease-Linked Hyperactivating Mutations In Ube3a Through Large-Scale Functional Variant Analysis, Kellan P. Weston, Xiaoyi Gao, Jinghan Zhao, Kwang Soo Kim, Susan E. Maloney, Jill Gotoff, Sumit Parikh, Yen Chen Leu, Kuen Phon Wu, Marwan Shinawi, Joshua P. Steimel, Joseph S. Harrison, Jason J. Yi

College of the Pacific Faculty Articles

The mechanisms that underlie the extensive phenotypic diversity in genetic disorders are poorly understood. Here, we develop a large-scale assay to characterize the functional valence (gain or loss-of-function) of missense variants identified in UBE3A, the gene whose loss-of-function causes the neurodevelopmental disorder Angelman syndrome. We identify numerous gain-of-function variants including a hyperactivating Q588E mutation that strikingly increases UBE3A activity above wild-type UBE3A levels. Mice carrying the Q588E mutation exhibit aberrant early-life motor and communication deficits, and individuals possessing hyperactivating UBE3A variants exhibit affected phenotypes that are distinguishable from Angelman syndrome. Additional structure-function analysis reveals that Q588 forms a regulatory site …

The Second-Order Impact Of Relative Power On Outcomes Of Crisis Bargaining: A Theory Of Expected Disutility And Resolve, Tatevik Movsisyan

Graduate Program in International Studies Theses & Dissertations

How does structure shape behavior and outcomes in crisis bargaining? Formal bargaining models of war rely on expected utility theory to describe first-order effects, whereby the payoffs of war determine actors’ “resolve” to fight as a function of costs and benefits. Value preferences of risk and future discounting are routinely treated as predefined and subjective individual attributes, outside the strategic context of bargaining or independent from expected utility. However, such treatment fails to account for context-conditional preferences sourcing from actors’ expectations of relative gain or loss. Drawing on a wealth of experimental evidence from behavioral economics, but without departing from …

A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors

Biology Faculty Publications

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation.

Augmented Reality-Assisted Problem-Based Learning E-Module To Improve Problem-Solving Skills, Zurienia Mimi Bibiyana, Fatchur Rohman, Mimien Henie Irawati Al-Muhdhar

Jurnal Pendidikan Sains

Problem-solving skills in the field of biology play an important role in representing problems, identifying relationships, making predictions, and verifying or evaluating solutions. This study aimed to implement an augmented reality-assisted problem-based learning e-module on bioindicator materials to improve students’ problem-solving skills. The research method used was a pre-experimental one-group pretest-posttest design involving 29 biology students at the State University of Malang in the 2020/2021 academic year. The results of the paired t-test showed that the significance value (p) for the pretest and posttest was 0.000 (< 0.05), indicating that the e-module had a significant effect on improving students’ problem-solving skills.

Synthesis Methodologies For Robust And Reconfigurable Clock Networks, Necati Uysal

Electronic Theses and Dissertations, 2020-2023

In today's aggressively scaled technology nodes, billions of transistors are packaged into a single integrated circuit. Electronic Design Automation (EDA) tools are needed to automatically assemble the transistors into a functioning system. One of the most important design steps in the physical synthesis is the design of the clock network. The clock network delivers a synchronizing clock signal to each sequential element. The clock signal is required to be delivered meeting timing constraints under variations and in multiple operating modes. Synthesizing such clock networks is becoming increasingly difficult with the complex power management methodologies and severe manufacturing variations. Clock network …

Translating Particulate Hexavalent Chomium-Induced Chromosome Instability, Loss Of Homologous Recombination Repair And Targeting Of Rad51 From Human Lung Fibroblasts To Human Bronchial Epithelial Cells., Idoia Meaza Isusi

Electronic Theses and Dissertations

Particulate hexavalent chromium [Cr(VI)] is a well-established human lung carcinogen. RAD51, a key protein in homologous recombination repair pathway, is inhibited after prolonged exposure to Cr(VI), leading to an increase in chromosome instability after prolonged exposures in human lung fibroblasts. chromosome instability is the proposed driver of Cr(VI) carcinogenesis. Since tumors from chromate workers develop from epithelial cells, we sought to translate these findings from human bronchial fibroblasts to human bronchial epithelial cells. We hypothesized Cr(VI) inhibits RAD51 after prolonged exposure leading to an increase in chromosome instability in human bronchial epithelial cells (BEP2D). We characterized the cytotoxicity and measured …

Part-Time., Anthony Mark Piedmonte

Electronic Theses and Dissertations

This thesis is a creative writing project in prose covering the first 70 pages of a novel manuscript titled Part-time. Part-time will center around a 25-year-old medical school dropout starting a new job at a neighborhood golf clubhouse and gym. This coming-of-age narrative follows Danny as he struggles with his sexual identity, student debt, and job outlook after returning to the privileged community he grew up in. This sample will introduce the major characters, the clubhouse setting, and the forming relationship dynamics. By the end of these pages, readers will gain insight into how the part-time employees of the Longwood …

"If Fear Wasn't Enough?!": African American Perceptions Of Policing After Breonna Taylor's Unprovoked Death., Moriah Antoinette Bellamy

Electronic Theses and Dissertations

This study investigates how African Americans perceive the racialization process in the criminal justice system following the death of Breonna Taylor. Focusing primarily on police-community relations in Louisville, KY, I find the Breonna Taylor case amplifies preconceived perceptions of race between civilian and non-civilian groups. To test the hypothesis that racialization in the criminal justice system has caused damaging effects on relations between African Americans and police, two virtual focus groups were designed to discuss participants’ experiences with law enforcement. My findings suggest that the racialization process in the criminal justice system negatively skewed African American civilians’ attitudes towards law …

A Soft Place To Land: The Importance Of Otherparenting At Pwis., Stephanie Renae Mayberry

Electronic Theses and Dissertations

This phenomenological study examined the importance of otherparenting performed by Black student affairs professionals at a predominantly White research-intensive institution in the mid-South. Otherparenting is a U.S. tradition that has West African roots in chattel slavery. Otherparenting is defined as those that assist blood mothers and fathers by sharing parenting responsibilities. Semi-structured interviews were conducted with seven participants across various functional units at the institution. The examination illustrated the commitment Black staff have in assisting Black students through the college campus rife with structural barriers, while also accounting for the level of taxation the commitment to otherparenting places on Black …

Hospital-Based Professional Spiritual Care: Evaluating The Utilization, Availability, And Impact Of Chaplains., Kelsey B. White

Electronic Theses and Dissertations

BACKGROUND: The Affordable Care Act, enacted in 2010, transformed healthcare policy and forced hospitals to reevaluate traditional methods for care delivery. Researcher advocated for patient-centered models of care to reduce costs, address inequitable access to services, and improve service quality. These models prioritize patient values, preferences, and beliefs inclusive of patients’ religious and spiritual needs. Professional chaplains provide religious and spiritual care within many hospital settings. This dissertation explored the characteristics of hospitalized persons using chaplains, the factors associated with a hospital reporting a chaplaincy department, and how those services impacted patient satisfaction. METHODS: The first analysis used a two-part …

Literacy Abilities Of Children And Adolescents With Williams Syndrome., Caroline Greiner De Magalhaes

Electronic Theses and Dissertations

In this dissertation I report findings from two studies of the literacy abilities of children with Williams syndrome (WS), a genetic disorder associated with intellectual disability. I had two overarching goals: 1) evaluate the applicability of theories of reading and spelling acquisition developed based on typically developing children to children with WS; and 2) provide results that would inform the development of targeted assessments and interventions. In Study 1, individual differences in phonological awareness, visual spatial perception, vocabulary, overall intellectual abilities, and reading instruction approach (systematic phonics vs. other approaches) for sixty-nine 6 – 7-year-olds (most of whom were in …

Local Feature Selection For Multiple Instance Learning With Applications., Aliasghar Shahrjooihaghighi

Electronic Theses and Dissertations

Feature selection is a data processing approach that has been successfully and effectively used in developing machine learning algorithms for various applications. It has been proven to effectively reduce the dimensionality of the data and increase the accuracy and interpretability of machine learning algorithms. Conventional feature selection algorithms assume that there is an optimal global subset of features for the whole sample space. Thus, only one global subset of relevant features is learned. An alternative approach is based on the concept of Local Feature Selection (LFS), where each training sample can have its own subset of relevant features. Multiple Instance …

Charting The Unknown: Examining The Prevalence And Correlates Of Seconday Traumatic Stress In Kentucky Probation And Parole Officers., Amanda Marie Roberts

Electronic Theses and Dissertations

The purpose of this dissertation was to discern the prevalence and magnitude of both exposure to traumatic events and Secondary Traumatic Stress (STS); as well as potential correlates of STS in a group of Probation and Parole officers in the state of Kentucky Department of Corrections (KY DOC). Participants (N=302) completed a written survey which asked them to indicate demographic variables (age, gender, and ethnicity), as well as several important occupational variables, namely years of experience in the KY DOC, caseload volume, prison work experience, and whether or not they are responsible for a sexual offender caseload. Participants were also …

Drone Location And Scheduling Problems In Humanitarian Logistics., Zabih Ghelichi

Electronic Theses and Dissertations

Unmanned Aerial Vehicles (UAVs), commonly referred to as drones, are a promising technology for the last-mile delivery of medical and aid items in humanitarian logistics. In emergency scenarios, like disasters, where transportation networks are destroyed and people are stranded, drones can accelerate the delivery of urgently needed items, e.g., food and water, insulin shots and blood pressure pills, to those trapped in the disaster-affected areas. Drones can also provide logistics services in many non-emergency situations by delivering medical items, e.g., vaccine shots and lab specimens, to remote communities and hard-to-access locations. The contribution of using UAVs goes beyond merely having …

Social Disorganization And Violent Crime Across Nonmetropolitan Areas Of Kentucky., Daniel Ray Jude

Electronic Theses and Dissertations

This macro-level study examines the effects of social disorganization predictors on violent crime registered in nonmetropolitan areas of Kentucky from 2012 to 2016. The study intends to expand the line of research interested in verifying the applicability of the social disorganization theory (Shaw & McKay, 1942), including its new theoretical developments, to non-urban settings and plans to contribute to the literature willing to provide a better understanding of violent crime in rural areas. In response to Narag et al.’s (2009) call for a theoretical integration of environmental contaminants among the ecological factors that influence variations in crime, the study also …