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Identification Of A Novel Protein Interaction That Elucidates The Mechanism Of Idiopathic Recurrent Miscarriages In Women With Nlrp2 Mutations, Nayeon Son Jan 2022

Identification Of A Novel Protein Interaction That Elucidates The Mechanism Of Idiopathic Recurrent Miscarriages In Women With Nlrp2 Mutations, Nayeon Son

Graduate Theses/Dissertations

The protein NOD-Like receptor pyrin domain containing 2 (NLRP2) is one member of a larger family of protein receptors that plays an important role in our innate immune system. In humans, the NLR family consists of 22 proteins. However, only about a half of NLRs’ functions are known, but many are pro-inflammatory, causing inflammation. NLRP2 has been identified to be a maternal effect gene regulating early embryo development in idiopathic recurrent miscarriages. In previous studies, mutations in the NLRP2 gene resulted in genetic maternal imprinting disorders due to NLRP2 regulating DNA methylation. However, the exact mechanisms involved in recurrent miscarriages …

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U-Pb Apatite Chronometry Of Intrusions In An Accretionary Metamorphic Belt In Western Idaho, Usa, Colleen Grace Rankin Jan 2022

U-Pb Apatite Chronometry Of Intrusions In An Accretionary Metamorphic Belt In Western Idaho, Usa, Colleen Grace Rankin

Graduate Theses/Dissertations

The Salmon River suture zone in west-central Idaho, USA records the tectonic processes where island arcs, similar to modern-day Japan, were accreted to the North American continent in the Jurassic and Cretaceous periods (160-90 million years ago). This suture zone contains metamorphic rocks that were buried deep within the crust at depths of 20 kilometers or more and have subsequently been brought to the surface. The exhuming processes responsible for the metamorphic rocks in the Salmon River suture zone remains unclear. Two competing hypotheses have been proposed to explain the transport of the rocks from the Salmon River suture zone …

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Evaluating The Effectiveness Of Self-Compassion Training With Disability Support Staff, Jessica M. Venegoni Jan 2022

Evaluating The Effectiveness Of Self-Compassion Training With Disability Support Staff, Jessica M. Venegoni

Graduate Theses/Dissertations

The current study sought to evaluate the effectiveness of self-compassion training with disability support staff concurrently completing their college education for career advancement. The intervention was guided by a combined Acceptance and Commitment Therapy (ACT) and Self-Compassion training framework. The ACT Matrix was utilized within the study prior to intervention to determine values within self-compassion and to identify three behaviors to target within the weekly self-compassion training, and daily behavior report (Polk and Schoendorf, 2014). During the intervention phase, daily reported self-compassion behaviors and weekly reported self-compassion scores were collected (Neff, 2003a; Belisle et al., 2022), as well as their …

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An Exploratory Analysis Of Bias Formation, Prejudice, And Discrimination Through Contextual And Functional Similarities Using The Theoretical Framework Of Relational Density Theory, Elana Keissa Sickman Jan 2022

An Exploratory Analysis Of Bias Formation, Prejudice, And Discrimination Through Contextual And Functional Similarities Using The Theoretical Framework Of Relational Density Theory, Elana Keissa Sickman

Graduate Theses/Dissertations

Behavior Analysis “attempts to improve the human condition through behavior change”, with behavior being the primary target (BACB, n.d.). However, considering the way people perceive, interact with, and establish relational frames within different contexts is widely misunderstood. Much of this research has expanded on the components found in Stimulus Equivalence (SE) and Relational Frame Theory (RFT) by providing a more modern approach to examining language and its treatment approach. Relational responding of individuals and groups may contribute to implicit biases, prejudice, and discrimination as well as how they operate within nested contingency systems. While critical theorists have provided foundations for …

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Study Of Electrical And Magnetic Properties Of Ni/Nio Nanocomposite Thin Film, Bishwajite Karmakar Jan 2022

Study Of Electrical And Magnetic Properties Of Ni/Nio Nanocomposite Thin Film, Bishwajite Karmakar

Graduate Theses/Dissertations

In this thesis, detailed magnetic and electrical transport properties of composite thin films consisting of antiferromagnetic NiO, and ferromagnetic Ni have been studied. Highly oriented NiO thin films were grown on sapphire (0001) substrate using pulsed laser deposition with varying growth parameters such as oxygen pressure of the chamber and the substrate temperature. To obtain various percentage mixtures of Ni and NiO by means of introducing point defects (oxygen vacancies) into the NiO crystal structure, the as-grown films were annealed in forming gas (Ar:96% and H2:4%) at a fixed temperature of 600C and varying annealing time (0.5h to 6h). X-ray …

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A Pilot Randomized Trial To Assess Motivating Operations In Delay Discounting Of Food, Breeanna Michelle Slusher Jan 2022

A Pilot Randomized Trial To Assess Motivating Operations In Delay Discounting Of Food, Breeanna Michelle Slusher

Graduate Theses/Dissertations

This pilot study addresses the impact motivating operations have on delay discounting of food in the presence of real food. Six participants were recruited and randomly assigned to three food stimuli groups (donut, vegetable, and control) and assigned to either a deprivation or non-deprivation condition within the group. Participants were asked to complete a set of questionnaires and a delay discounting task. Demographics and anthropometric measurements were obtained from each participant. The pilot study showed support for previous delay discounting research that as the delay to more nutrient dense meals increases the subjective value of the delayed reward decreases. Thus, …

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Analysis Of Root System Architecture And Qtl Identification In Grapevines, Sujan Thapa Jan 2022

Analysis Of Root System Architecture And Qtl Identification In Grapevines, Sujan Thapa

Graduate Theses/Dissertations

The root system of the plant plays a vital role in water and nutrient uptake. Native North American grapevines adapted to a broad range of climatic and soil conditions, which led to the evolution of diverse root system architecture (RSA) within the Vitis genus. Despite the importance of RSA in viticulture, little is known about the genetic basis of the RSA in grapevine. I used novel root phenotyping tool, RhizoVision Analyzer to characterize the root system of 208 genotypes of an F1 grapevine progeny obtained from a cross between Vitis rupestris Scheele B38 and Vitis riparia Michx. HP-1. Dormant …

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Shadow-Based Automatic Building Height Estimation From High Spatial Resolution Satellite Imagery, Lonnie Lee Byrnside Iii Jan 2022

Shadow-Based Automatic Building Height Estimation From High Spatial Resolution Satellite Imagery, Lonnie Lee Byrnside Iii

Graduate Theses/Dissertations

Three-dimensional city (3D) models are very useful in supporting natural disaster preparation and response. LiDAR surveying is currently the main method by which 3D city models are created; however, LiDAR data on a local scale is hard to obtain for developing countries. This project sought to test whether or not urban feature height data obtained using the photogrammetric sun-angle shadow method is a viable alternative to LiDAR-derived 3D city models. A core element of this work was the development of a toolset to be shared freely to the public to promote crowdsourcing of 3D building data. Prior works were reviewed …

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Using Scorecards To Improve The Performance Of Behavior Technicians In An Autism Treatment Clinic, Carly M. Ruether Jan 2022

Using Scorecards To Improve The Performance Of Behavior Technicians In An Autism Treatment Clinic, Carly M. Ruether

Graduate Theses/Dissertations

Staff performance is important to the success of businesses and employers often use different methods to increase staff performance and motivate their staff. Performance scorecards, goal setting, and feedback are some methods of increasing staff performance. The goal of the current study was to partially replicate and extend Griffin et al.’s (2019) study utilizing performance scorecards to increase targeted behaviors of employees. In the current study, pre-intervention survey results were used to inform the choice of intervention based on deficiencies. Based on the results of the pre-intervention questionnaire, it was concluded that “task clarification and prompting” and “performance consequences, effort, …

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Role Of Cyclophilin A And Trim5Α In Hiv-1 Infection And Capsid Uncoating, Emma Lk Wise Jan 2022

Role Of Cyclophilin A And Trim5Α In Hiv-1 Infection And Capsid Uncoating, Emma Lk Wise

Graduate Theses/Dissertations

Microglial cells are immune cells that protect the central nervous system and are subject to HIV- 1 infection. HIV-1 infection of these cells can lead to HIV Associated Neurocognitive Disorders (HAND). Since HIV-1 only codes for 15 different proteins, the virus also uses cellular factors, like Cyclophilin A (CypA), to assist in viral replication. The cell also has antiretroviral restriction factors, like tripartite motif-containing protein 5 (TRIM5α), to protect against infection. The goal of this project is to investigate the role of CypA in the early steps of HIV-1 replication and TRIM5α restriction in microglial cells. I hypothesize that CypA …

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Garlic Curing: Post-Harvest Nutrient Remobilization From Leaves To Cloves, Mary L. Books Jan 2022

Garlic Curing: Post-Harvest Nutrient Remobilization From Leaves To Cloves, Mary L. Books

Graduate Theses/Dissertations

Garlic (Allium sativum L.) is grown on small and large scales worldwide. After harvesting, garlic undergoes a drying process for long-term preservation, called curing. Some producers cure with leaves intact, while others will remove and discard the leaves, curing only the bulbs. Due to the ability of plants to remobilize nutrients from leaves to underground storage organs, such as bulbs, the curing method of garlic may affect clove nutrient content. This study explores nutrient remobilization responses in garlic when cured with leaves intact compared to leaves separated from bulbs. Four cultivars of garlic, German White, Chesnok Red, Romanian Red, and …

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The Influence Of Psychological Safety On Leadership Attitudes And Beliefs In College Students, Ján Koperniech Jan 2022

The Influence Of Psychological Safety On Leadership Attitudes And Beliefs In College Students, Ján Koperniech

Graduate Theses/Dissertations

The goal of the present study is to examine whether there is a link between experiences of psychological safety and certain beliefs and attitudes college students have about organizational leadership. While the locus of most of the research on psychological safety is the workplace, this study examines the effects of psychological safety in three environments: home, school, and work. One-hundred and ninety-nine psychology students reported their experiences and attitudes by completing an online survey. The results showed no significant relationship between psychological safety and systemic and hierarchical beliefs about leadership. The findings, as well as recommendations for future research, are …

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Intercropping Grain Sorghum Into Established Rhizoma Peanut: Greenhouse And Field Studies, Erika Hm Cooperman Jan 2022

Intercropping Grain Sorghum Into Established Rhizoma Peanut: Greenhouse And Field Studies, Erika Hm Cooperman

Graduate Theses/Dissertations

Land degradation and urbanization are among the top factors pushing the Kenyan Maasai community into an unstable future, with food insecurity and poverty amidst the most fragile components. Implementing conservation agricultural techniques into the Maasai nomadic lifestyle could potentially lead to a diversification of finances and food security. Intercropping is one technique of conservation agriculture that could provide the Maasai both. The main objective of this study is to evaluate the effects of creating an intercropped environment between rhizoma peanut and grain sorghum. A greenhouse study was conducted from late 2020 to 2021 in an effort to investigate the effects …

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The Role Of Actin Associated Sptbn1 Host Factor In Hiv-1 Infection In Microglial Cells, Hannah Matheney Jan 2022

The Role Of Actin Associated Sptbn1 Host Factor In Hiv-1 Infection In Microglial Cells, Hannah Matheney

Graduate Theses/Dissertations

Human immunodeficiency virus (HIV) is a chronic illness affecting more than 32.7 million individuals worldwide. The virus infects immune cells, weakening the immune system overtime eventually leading to acquired immunodeficiency syndrome (AIDS) if left untreated. Infection starts with a fusion step, followed by uncoating of the HIV capsid once in the cytoplasm of the cell. HIV uses host cell proteins to complete the infection process, like the actin associated factor, SPTBN1. The Hulme lab has previously shown that SPTBN1 knockdown by siRNA in microglial cells decreased HIV infection and delayed uncoating of HIV. Because fusion is prior to uncoating, it …

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A Study Of Cobalt (Iii) Oxide Nanoparticle Delivery Of Sirna Molecules Directed Against Signaling Intermediates Of The P2y2 Receptor, Rachel Blair Stroud Jan 2022

A Study Of Cobalt (Iii) Oxide Nanoparticle Delivery Of Sirna Molecules Directed Against Signaling Intermediates Of The P2y2 Receptor, Rachel Blair Stroud

Graduate Theses/Dissertations

G protein-coupled receptors are evolutionarily ubiquitous sensors of extracellular signals, propagating intracellular signal cascades through heterotrimeric G proteins. P2Y2 receptors are GPCRs which are activated by extracellular nucleotides to mediate signaling cascades via Gαq coupling. Many GPCRs are subject to a common mechanism for signal termination involving phosphorylation of the C-terminal tail followed by β-arrestin binding and subsequent endocytic internalization of the complex. This effect has been described for the P2Y2 R in the 1321N1 astrocytoma cell line, and UTP-induced activation and desensitization profiles have been previously defined. There is need to develop molecular vehicles for safe and …

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Queering Job: Inverted Liberation In Boy Erased And Other Conversion Trauma Narratives, Harrison Beau Palen Jan 2022

Queering Job: Inverted Liberation In Boy Erased And Other Conversion Trauma Narratives, Harrison Beau Palen

Graduate Theses/Dissertations

This thesis explores conversion trauma narratives with the goal of transforming—inverting The Book of Job’s holy resolution to instead entail queer liberation apart from Evangelicalism. Analyzing Conley’s bestselling memoir, Boy Erased, I discuss Conley’s suffering and how his liberation is not found by means of repressing or converting his attraction to the same gender. I also analyze Emily Danforth’s novel, The Miseducation of Cameron Post to highlight how fictional accounts of queer liberation from conversion therapy help to increase awareness of the harms of conversion therapy. Throughout my thesis, I incorporate my own story of queer suffering, survival, and …

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Splitleaf, Sean M. Turlington Jan 2022

Splitleaf, Sean M. Turlington

Graduate Theses/Dissertations

Set in the fantasy world of Vriim, Splitleaf follows the story of the protagonist Dellum Lovira as he journeys to regain his freedom, find purpose in his life once he has freedom, and develop into a self-actualized person beyond the shadow of his mother and the societal judgement for his multiracial status. Raised on the island chain of Riitol, Dellum is a half-blood between a human father and a Nifaren mother, a race of scaled and feathered people whose emotional investment struggles to move beyond self-interest. He must in the early chapters included here travel back to his original home, …

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Reducing Family Risk Factors Caused By Poverty Through Family Support Services, Aaliyah C. Williams Jan 2022

Reducing Family Risk Factors Caused By Poverty Through Family Support Services, Aaliyah C. Williams

Graduate Theses/Dissertations

This study aims to determine whether preventative measures are effective if implemented while a family is in crisis, through Family Support Services (FSS), to alleviate Risk Factors, prevent family separation and ensure prolonged family stability, instead of as services to reunify a family that already separated due to a lack of resources. This study examined the Poverty Related Risk Factors of Homelessness, Single Parenthood, and Unemployment as Risk Factors that families enrolled in Ozarks Area Community Action Corporation (OACAC) Head Start experience as negative influences on child development and Family Unity and analyzed OACAC Head Start’s implementation of FSS as …

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Qualitative Comparison Of The United States And United Kingdom Healthcare Systems, Rachel Cazzaniga Jan 2022

Qualitative Comparison Of The United States And United Kingdom Healthcare Systems, Rachel Cazzaniga

Graduate Theses/Dissertations

The United States and United Kingdom healthcare systems vary based on their public access, financial dependence, health outcomes, gross domestic product, and much more. The systems have continued to grow with different focuses of importance in the quality of care that is being distributed to their populations. The U.K. universal healthcare system represents their value of accessibility and affordability, while the U.S. privatized system(s) represents their value of economic growth. The study provided a qualitative analysis of the systems' differences by integrating real world experiences and perceptions of the systems from individuals that have encountered and interacted as a patient …

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Physical Activity As A Predictor Of Obesity In Autistic Children, Cody A. Mullins Jan 2022

Physical Activity As A Predictor Of Obesity In Autistic Children, Cody A. Mullins

Graduate Theses/Dissertations

Research has found autistic children to be 40% more likely to be obese compared to their non-autistic peers. Reduced physical activity (PA) is thought to be a contributing factor to the increased prevalence of obesity in autistic children. This was one of the first studies to investigate the PA behaviors of autistic children during an adapted physical education (APE) class using accelerometry. The purpose of this study was to examine the PA of autistic children and determine the relationship between PA and obesity. Participants were recruited from a school for students with disabilities who participate in a once-weekly APE class …

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Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy Jan 2022

Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy

Graduate Theses/Dissertations

Peritonitis is an inflammatory condition affecting the mesothelial cells that line the peritoneal cavity and is commonly induced by bowel perforations. This medical emergency is treated through antibiotic therapy and surgical intervention followed by tissue irrigation (lavage). Acute treatments aim to remove the bacterial burden, however recurring peritoneal infections occur at high rates and contribute to patient morbidity. These recurring infections are likely due to the inability of lavage solutions to remove the entire massive intra-abdominal bacterial load due to intestinal perforation. Numerous antiseptic solutions and antibiotic additives have been evaluated in their ability to improve source control by abdominal …

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Parent Style Of Coping Based On Attachment In The Nicu, Claire Elizabeth Payne Jan 2022

Parent Style Of Coping Based On Attachment In The Nicu, Claire Elizabeth Payne

Graduate Theses/Dissertations

This quantitative study sought to identify any relationship between attachment type and coping style in the Neonatal Intensive Care Unit, to better understand and provide resources and support to families in this environment. This study included ten participants who had an infant in the Neonatal Intensive Care Unit for at least five days. Each participant met the additional criteria of being older than the age of 18 and speaking English. Responses were recorded through a self-report survey, consisting of 115 Likert scale statements. Results indicated that most parents self-report secure attachment and that styles of coping varied within those securely …

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On The Synthesis And Characterization Of Bimagnetic Coo/Nife2o4 Heterostructured Nanoparticles, Muhammad Sharif Uddin Jan 2022

On The Synthesis And Characterization Of Bimagnetic Coo/Nife2o4 Heterostructured Nanoparticles, Muhammad Sharif Uddin

Graduate Theses/Dissertations

Bimagnetic nanoparticles show promise for applications in energy efficient magnetic storage media and magnetic device applications. The magnetic properties, including the exchange bias of nanostructured materials can be tuned by variation of the size, composition, and morphology of the core vs overlayer of the nanoparticles (NPs). The purpose of this study is to investigate the optimal synthesis routes, structure and magnetic properties of novel CoO/NiFe2O4 heterostructured nanocrystals (HNCs). In this work, I aim to examine how the size impacts the exchange bias, coercivity and other magnetic properties of the CoO/NiFe2O4 HNCs. The nanoparticles with sizes ranging from 10 nm to …

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The Me [Unnamed]: Essays, Rebecca Ann Harris Jan 2022

The Me [Unnamed]: Essays, Rebecca Ann Harris

Graduate Theses/Dissertations

This creative thesis includes six flash nonfiction pieces and four essays exploring my relationships with my father, mother, and older sister; this exploration is filtered through the lenses of trauma and mental illness. Notably, five of the six flash nonfiction pieces are written in the literary mode of magical realism, which are analyzed in this thesis’ critical introduction. By evaluating magical realism’s origins in German surrealism and its development within Latin-America—as well as its theoretical correlation to Charles Baxter’s defamiliarization and Milan Kundera’s appeal of dream—I acknowledge magical realism’s literary techniques and cultural motivations within published fiction. I analyze magical …

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Optimizing The Fluorescent Quantum Yield Of Carbon Dots, Megan B. Prado Jan 2022

Optimizing The Fluorescent Quantum Yield Of Carbon Dots, Megan B. Prado

Graduate Theses/Dissertations

Carbon dots (CDs) are a subclass of carbon nanomaterials that exhibit unique properties of fluorescence, photostability, low toxicity, and biocompatibility. These unique properties have enabled numerous applications including biosensing, heavy-metal detection, and pH-sensing, among others. Their optical properties can be modified via doping to produce increasingly fluorescent CDs after appropriate purification. Herein, doped CDs were synthesized in four bottom-up methods for comparison using sucrose or citric acid as carbon precursors. Varying hetero-atom dopants (N, S, B) were used in differing molar ratios. The pH-dependent fluorescence and fluorescent quantum yield (QY) were measured for each sample. Characterization was conducted using Fourier-Transform …

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Testing The Impact Of A Silencing Suppressor On Infectivity Of Grapevine Vein Clearing Virus Infectious Clone In Nicotiana Benthamiana, Wen Zhao Jan 2022

Testing The Impact Of A Silencing Suppressor On Infectivity Of Grapevine Vein Clearing Virus Infectious Clone In Nicotiana Benthamiana, Wen Zhao

Graduate Theses/Dissertations

Grapevine vein clearing virus (GVCV), the first DNA virus of the Badnavirus genus discovered in grapevines, is closely associated with grapevine vein-clearing disease. Through earlier research, Koch's postulates were partially met: GVCV was in all diseased plants; GVCV was introduced into a healthy grapevine through grafting and by aphids and caused the disease. However, more shreds of evidence are required to fulfill the last postulate, the same virus must be reisolated from the inoculated diseased grapevine (1). A full-length infectious clone of GVCV was previously constructed to provide evidence; however, its infectivity was not consistent. Therefore, the goal …

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Project-Based Learning And Social-Emotional Learning In The Elementary Classroom: A Qualitative Study On Potential Opportunities For Student Self-Awareness And Social Awareness, Kaitlin Eileen Kilby Jan 2022

Project-Based Learning And Social-Emotional Learning In The Elementary Classroom: A Qualitative Study On Potential Opportunities For Student Self-Awareness And Social Awareness, Kaitlin Eileen Kilby

Graduate Theses/Dissertations

Project-based learning (PBL) is a student-centered instructional practice, emphasizing student agency, engagement, and learning opportunities through relevant problem-solving and interdisciplinary curriculum. PBL also helps students develop academic and social skills through real-world application of their learning. It is necessary for educators, administrators and interested parties in education to understand the potential of PBL and other student-centered practices on increasing student engagement and achievement in subject areas besides sciences and social studies, such as literacy, math, and social-emotional learning (SEL). SEL is necessary for all students to have access to, as engaging with activities that increase a person’s ability to understand …

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Effects Of Natural Products On Inflammation, Riley Ann Nadler Jan 2022

Effects Of Natural Products On Inflammation, Riley Ann Nadler

Graduate Theses/Dissertations

Chronic inflammation is characterized by infiltration of inflammatory cells such as macrophages and lymphocytes into the tissue where they produce inflammatory cytokines that contribute to tissue damage. Worldwide, 3 out of 5 people die due to chronic inflammatory diseases like cardiovascular diseases, obesity, diabetes, and cancer. Since it is well-documented that diet and metabolism are key mediators of inflammation, I investigated the effects of dietary lectins on inflammatory cytokine production and the ability of sodium pyruvate, a metabolite, to decrease inflammation. In chapter 1, I examined the effect that lectins from either Triticum vulgaris (common wheat) or Phaseolus vulgaris (common …

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Emotion Validating Language Regarding Negative Emotions In The Classroom Differing By Gender And Emotion Type, Tea Rose Pankey Jan 2022

Emotion Validating Language Regarding Negative Emotions In The Classroom Differing By Gender And Emotion Type, Tea Rose Pankey

Graduate Theses/Dissertations

This study examined teachers’ emotion validating language regarding negative emotion in early childhood classrooms. By analyzing teachers’ emotion language differing by gender, the research highlights the gendered socialization of emotional expression, especially regarding negative emotions, in early childhood contexts. In toddler and preschool classrooms, 28 teachers were video recorded during 4 thirty-minute sessions of free play time. Videos were coded for teachers’ emotion language regarding negative emotions with attention to the gender of the child to whom the language was spoken. Results indicate that teachers validate negative emotions more to girls than to boys. This aligns with previous research that …

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Planning And Effects Of Equitable Teaching Practices In Emu Math 120 Class, Kyle Yapp Jan 2022

Planning And Effects Of Equitable Teaching Practices In Emu Math 120 Class, Kyle Yapp

Senior Honors Theses and Projects

The purpose of this project is to evaluate the effects of implementing Equitable Teaching practices in Math 120 Calculus 1. We used the EQUIP instrument in order to measure the amount of participation from each student. We used the X-PIPS-M instrument in order to get the students' responses to the class as well as have Dr. Ross reflect as a teacher. We used the MCOPP+ in order for Dr. Ross to reflect as a teacher. We also used the Calculus 1 Concept Inventory assessment in order to evaluate students' content knowledge growth during the course. We found that students responded …

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