Digital Commons Network^™

Pace O Matic Inc V. Eckert Seamans Cherin & Mellott Llc

2026 Decisions

USDC for the Middle District of Pennsylvania

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

Francisco Merino-Angel V. Attorney General United States Of America

2026 Decisions

Agency

Who Lets Ai Take Over? Cross-National Variation In Willingness To Delegate Socially Important Roles To Artificial Intelligence, Ala Yankouskaya, Mohamed Basel Almourad, Magnus Liebherr, Fahad Beyahi, Guandong Xu, Raian Ali

All Works

Delegating socially significant roles to artificial intelligence (AI) is an emerging reality, yet little is known about how publics evaluate this transfer of responsibility across contexts and countries. This study applied a structural model to a large cross-national dataset (30,994 individuals in 35 countries) to test how cognitive appraisals, affective dispositions, and contextual factors jointly shape willingness to delegate socially important roles of companionship, mental health advisor, doctor and teacher to children to AI. The results revealed a robust hierarchy of delegation preferences, with companionship most frequently entrusted to AI, followed by mental-health advisor, teacher, and doctor. Cognitive appraisals emerged …

Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte

Faculty Publications

Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …

Effective Wordle Heuristics, Ronald I. Greenberg

Computer Science: Faculty Publications and Other Works

While previous researchers have performed an exhaustive search to determine an optimal Wordle strategy, that computation is very time consuming and produced a strategy using words that are unfamiliar to most people. With Wordle solutions being gradually eliminated (with a new puzzle each day and no reuse), an improved strategy could be generated each day, but the computation time makes a daily exhaustive search impractical. This paper shows that simple heuristics allow for fast generation of effective strategies and that little is lost by guessing only words that are possible solution words rather than more obscure words.

Emerging Threats In Ai: A Detailed Review Of Misuses And Risks Across Modern Ai Technologies, Niyat Seghid, Farkhund Iqbal, Khalifa Al-Room, Áine Macdermott

All Works

The swift evolution of artificial intelligence (AI) has enabled unprecedented capabilities across domains, while simultaneously introducing critical vulnerabilities that can be maliciously exploited or cause unintended harm. Although multiple initiatives aim to govern AI-related risks, a comprehensive and systematic understanding of how AI systems are actively misused in practice remains limited. This paper presents a systematic review of AI misuse across modern AI technologies. We analyze documented incidents, attack mechanisms, and emerging threat vectors, drawing from existing AI risk repositories, prior taxonomies, and empirical case reports. These sources are synthesized into a unified analytical framework that categorizes AI misuse across …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Predictive Accuracy Of Hill-Rbf 3.0 Versus Other Intraocular Lens Power Calculation Methods: Systematic Review And Meta-Analysis, Xiaole Li, Ronald Cheung, Manav Nayeni, Salem Abu Al-Burak, Prisha Dave, Bo Li, Monali S. Malvankar-Mehta

Student Publications

Objective: Amid growing adoption of AI in ophthalmology, Hill-Radial Basis Function (Hill-RBF) 3.0 formula may improve refractive target prediction across diverse populations, transforming patient care. This systematic review and meta-analysis (PROSPERO: CRD42021231150) evaluated the predictive performance of the Hill-RBF 3.0 against other traditional and AI-based intraocular lens (IOL) power calculation formulas.

Design: Systematic review and meta-analysis.

Methods: EMBASE, MEDLINE, CINAHL, and Web of Science were searched on March 17, 2025. Eligible studies reported refractive or cataract surgeries using Hill-RBF 3.0 and at least 1 comparable formula (Barrett Universal II, EVO 2.0, Haigis, Hoffer Q, Hoffer QST, Holladay I, Ladas Super …

Small Patients, Big Gaps: Why Adult Crrt Timing Evidence Does Not Translate To Children, Katja M Gist, Dana Y Fuhrman, Ayse Akcan-Arikan

Faculty, Staff and Students Publications

No abstract provided.

Spartan Daily, February 12, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 10

Targeting Oxalate Production By Combining Enzyme Inhibition And Proteolysis Activation: A Novel Therapeutic Approach For Primary Hyperoxaluria Type 1, Fabio Arias, Sumati Rohilla, Yudibeth Sixto-López, Koral S E Richard, Sandeep Das, Sumit K Anand, Pilar Maria Luque-Navarro, Guillermo Bañuelos-Sanchez, Juan Luis Pacheco-García, Reethika Gade, M Peyton Mckinney, Dhananjay Kumar, Jemiah Maxie, W Rylan Corr, Nilesh Pandey, Harpreet Kaur, Jibin Ding, Lin Tan, Elisha Scott, Hyung Nam, Eyal Gottlieb, A Wayne Orr, Nirav Dhanesha, Arif Yurdagul, Angel L Pey, Francisco Franco-Montalbán, José A Gómez Vidal, Oren Rom, Mónica Díaz-Gavilán

Faculty, Staff and Student Publications

Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder caused by hepatic oxalate overproduction due to alanine-glyoxylate aminotransferase (AGXT) deficiency. Therapeutic strategies targeting glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), key enzymes in glyoxylate metabolism, have shown promise in reducing oxalate burden. However, recently approved siRNA therapies remain limited by high cost, unfavorable pharmacokinetics, and limited global accessibility. We report the development of compound 2, a dual GO/LDHA inhibitor (K i = 390 and 40 nM, respectively) that also promotes hydrophobic tag-mediated autophagic degradation of LDHA. Its efficacy was evaluated in Agxt –/– mice, both in primary …

Serial False Lumen Patency Evaluation Of A Type B Dissection Represented With Malperfusion Following Medical Management, S Taha Zaidi, Quang Le, Firas Mussa, Akiko Tanaka, S Keisin Wang, Arash Keyhani, Kourosh Keyhani

Faculty, Staff and Student Publications

False lumen evolution in type B aortic dissection, particularly with medical management and anticoagulation, remains incompletely understood. We report a 55-year-old man on apixaban for pulmonary embolism with a subacute zone 3-10L TBAD without malperfusion. He was managed medically initially and represented twice over 2 months with back pain and acute right lower extremity ischemia. Serial imaging demonstrated dynamic remodeling with progression from partial to near-complete thrombosis to full reperfusion with true lumen compression. Urgent endovascular repair was performed successfully. This case illustrates the unpredictable course of medically managed TBAD and need for judicious use of anticoagulation.

Primary Tumor Size And Tumor-Vessel Interface Following Capecitabine And Temozolomide For Pancreatic Neuroendocrine Tumor, Jin Guo, Kever A Lewis, Laura Prakash, Priya Bhosale, Ajaykumar Morani, Matthew H G Katz, Ching-Wei D Tzeng, Naruhiko Ikoma, Rebecca Snyder, Michael P Kim, Chandrikha Chandrasekharan, Arvind Dasari, James C Yao, Jeffrey E Lee, Jessica E Maxwell, Daniel M Halperin

Faculty, Staff and Student Publications

Capecitabine/temozolomide (CAPTEM) is an established regimen for patients with metastatic pancreatic neuroendocrine tumors (PanNET) that is being increasingly used for tumor volume reduction in patients with borderline anatomically resectable disease. We sought to understand the response of the primary tumor, defined as changes in the tumor–vascular interface (TVI). This is a retrospective, single-institution study of patients with locally advanced or metastatic PanNET treated with CAPTEM between 2010 and 2020. RECISTv1.1 measurements and TVI assessments of the primary tumor were performed on pre- and post-therapy images. Patients with locally advanced or metastatic PanNET at presentation (n = 47) were included. …

Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yang Cai, Yu Ren, Hao Yuan, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li

Faculty, Staff and Student Publications

Cancer-induced cachexia and anorexia are debilitating complications across many cancers, yet effective treatments remain limited due to a poor understanding of the underlying mechanisms. Here, we identify an uncharacterized tumor-immune-neural circuit driving these syndromes, centered on growth and differentiation factor 15 (GDF15). Using genetically engineered mouse models, we find that loss of GDF15 protects against appetite loss, muscle wasting, and fat loss in pancreatic, lung, and skin cancers. Single-cell RNA sequencing reveals macrophages as a major source of GDF15, induced by tumor-derived colony-stimulating factor 1 (CSF1). GDF15 acts via the central nervous system to enhance β-adrenergic signaling in the tumor …

Weight Loss Patterns And Clinical Outcomes Of Glp1 Receptor Agonists In Breast Cancer Survivors, Jasmine S Sukumar, Akshara Singareeka Raghavendra, Sarah Pasyar, Roland L Bassett, Debu Tripathy, Carlos H Barcenas, Karen M Basen-Engquist, Banu K Arun

Faculty, Staff and Student Publications

Use of glucagon-like peptide-1 receptor agonists (GLP1-RA) for weight loss is increasing; implications in breast cancer (BC) survivors remain unclear.This retrospective cohort study evaluated treatment patterns, weight loss, and outcomes in BC survivors at an academic institution receiving GLP1-RA. We evaluated patients with non-metastatic (ductal carcinoma in situ (DCIS), stage 1-3) BC who received GLP1-RA (2005 - 2024). Linear regression models estimated associations between weight change and clinical factors. After excluding DCIS, propensity score matching (1:2) was used to match patients who received GLP1-RA with patients who did not, based on confounding covariates. Kaplan-Meier estimates and log-rank tests compared disease-free …

Artificial Intelligence In The Prosecution Of International Crimes, Marta Bo

International Law Studies

International criminal prosecutions face growing evidentiary challenges due to the vast and heterogeneous digital material generated during conflicts, including user-generated videos, social media, and intercepted communications. This article examines the potential role of artificial intelligence (AI) in supporting investigations and trials before the International Criminal Court (ICC). Rather than replacing judicial decision-making, AI can assist with specific tasks, particularly in establishing contextual elements and linkage evidence central to international crimes. The article explores three main areas: AI-driven biometric tools for facial and speech recognition; AI techniques for detecting patterns of violence and mapping command structures; and applications during trial proceedings, …

Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist

Department of Agricultural Economics Faculty Publications

Public stockholding of food is politically contentious and economically challenging. Although private stocks are generally understood to be more efficient than public stocks at providing a reliable buffer against production shortfalls, private stocks often fail to stabilize prices during extreme food market shocks. Moreover, maintaining large public stock programs in which the government acts as the buyer or seller of last resort, can be very costly. This paper analyzes the recent historical success of public and private rice stocks in stabilizing domestic rice prices in the Philippines, the world’s largest net importer of rice. Relying on competitive storage theory and …

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

February 12, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier

All Current Publications

This fact sheet provides women with basic information about perimenopause, menopause, and postmenopause, along with helpful tips and resources to better prepare for or manage these phases of life.

Systematic Synthesis Of Crispr/Cas Applications For Enhancing Salt Tolerance In Crops: A Decade Of Progress And Challenges, Xindi Sun, Fusheng Wu, Zhuanzhuan Ma, Guohao Liang, Shumei Chen, Xutong Hu, Shugao Fan, Ying Zhao

School of Mathematical & Statistical Sciences Faculty Publications

Soil salinity is a major constraint on global crop productivity, driving the need for salt-tolerant varieties. While CRISPR-Cas genome editing offers targeted solutions for trait improvement, significant biological and technical bottlenecks limit its application in conferring salt stress resilience. This systematic summarizes findings from 83 peer-reviewed studies (2015–2024) employing CRISPR/Cas technologies to improve salt tolerance in five major crops (rice, wheat, maize, sorghum, barley). Our systematic review reveals that early single-gene edits achieved modest gains (30–50% Na⁺ exclusion) but often showed limited yield gains in field settings, potentially due to compensatory regulation and environmental variation. The literature suggests that multiplex …

Quaker Campus, February 12, 2026 (Vol. 24, Issue 8), Whittier College

Quaker Campus

No abstract provided.

Kenyon Collegian - February 12, 2026

The Kenyon Collegian

No abstract provided.

20260212: President's Papers, 1957-1990, President's Office

Guides to University Archives

These items include materials from the Office of the President at Marshall University from 1957-1990 Items were received in the 1990s and were accessioned/inventoried in 2026. Items within this collection include materials from the Distinguished Lecture Series as well as "The Scott Lectures" from 1959-1963. Other materials include campus events, most likely, and other formal writings about higher education. Of note: "An Informal, Incomplete Introduction to Appalachian Culture" by Dr. O. Normal Simpkins. This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

Geometry Of Neural Dynamics Along The Cortical Attractor Landscape Reflects Changes In Attention, Hayoung Song, Ruiqi Chen, Thomas L Botch, Todd S Braver, Monica D Rosenberg, Jeffrey M Zacks, Shinung Ching

2020-Current year OA Pubs

Large-scale brain activity reflects changes in attention. To understand how, we tested a hypothesis that the geometry of neural dynamics on the cortical attractor landscape, or movement along its "hills and valleys", reflects attentional states. A dynamical systems model separating intrinsic dynamics from stimulus-driven influences was fit to fMRI data collected during rest, tasks, and movie-watching. Model simulations revealed a set of attractors aligned with canonical functional brain networks. The speed and direction of neural trajectories toward these attractors varied systematically with attentional states over time and across contexts. When participants were paying attention to effortful tasks, neural dynamics converged …

Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A Bender, Harrison M Dunn, Arushi D Mohite, Akila Anandarajah, Jacob Steinle, Suraj Shankar, Brandon Kiley, Sara Martin, Rishi Gonuguntla, Mia Stonov, Nithya Pippala, Rana Abdalla, Madison K Stille, Gibson Werner, Melinda Daniels-Tineo, Hannah Wang, Sonali Sharma, Jatin Sridhar, Adebusola Adeyemi, Kayla Smart, Baris C Ercal, Et Al.

2020-Current year OA Pubs

BACKGROUND: The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.

AIMS: To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.

METHOD: Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter and sentiment.

RESULTS: In total, 88.3% of screened URLs (3308 of 3747) were included in the analysis. The proportion of articles focusing on the therapeutic potential of psychedelics …

Sandra Ann Collins

African American Funeral Programs

Program for the funeral of Sandra Ann Collins held at St. Phillip Monumental Ame Church

Owning The Game: Multi-Club Ownership And The Battle For Competitive Integrity In Global Football, Juan Carlos Vazquez-Valderas, Emma Steinweiss, Nickolas Bruscargin, Sherry Andre

Faculty and Staff Publications & Presentations

Presented research at the GSBA Conference examining the rise of multi-club ownership in global football and its implications for competitive balance, governance, and stakeholder trust. The session explored how shared ownership structures can create both strategic advantages and ethical challenges, while encouraging discussion on protecting integrity within the global sport industry.

Activating Learning With Ai: Early Evidence From Undergraduate Sports Management Courses, Sherry Andre

Faculty and Staff Publications & Presentations

Presented research at the GSBA Conference on integrating AI into undergraduate sport management courses to enhance student engagement, critical thinking, and applied learning. The session shared early evidence on how AI can support skill development, improve classroom experiences, and better prepare students for careers in the evolving sport industry.