Digital Commons Network^™

Applying The Lean Process To Achieve The Quadruple Aim In Community Care Imaging Consults, Cynthia L. Austin

Creating Healthy Work Environments (CHWE)

Introduction: Care coordination has been challenging in scheduling high-risk patients needing diagnostic imaging procedures. Missing crucial patient information can lower the value of patient-reported outcomes because it influences decision-making in care plans, results in duplication of services, and delays the delivery of care or treatments (Ayilara et al., 2019). Incomplete data delays diagnostic procedures, diagnosis, and medical treatments (Fernholm et al., 2019). Numerous studies have revealed that prolonged waiting times are frequently the leading cause of patients' discontent with outpatient scheduling, and equitable waiting periods are necessary based on clinical competency (Ala & Chen,2022). Medical imaging methods frequently cause increased …

The Impact Of A Coaching Program On Student Retention In An Associate Degree Nursing Program, Angela J. Dryden

Creating Healthy Work Environments (CHWE)

Student success in college is judged by retention and graduation rates (Millea et al., 2018). Nursing student retention and attrition are identified as ongoing areas of international concern. Academic failure is known to impact students, their families, the institutions, and the greater communities in relation to the overall nursing shortage (Brown et al., 2020). Nursing students that do not progress affect the present nursing shortage since the failure leaves an opening that is then not filled (Cross & Rogers, 2022). For those institutions that may have a direct relationship with a health system, students who do not progress have an …

Can Offering Mental Health Promotion Mhealth Apps To Hospital Nurses Improve Mental Health And Well-Being?, Cynthia A. Moore, Stephanie Kelly

Creating Healthy Work Environments (CHWE)

Background: Post-pandemic surveys show hospital nurses continue to struggle with anxiety, depression, burnout, and stress, and to a greater degree than before the pandemic¹. In 2022, approximately half of nurses surveyed reported an interest in leaving their current job or leaving nursing altogether². Few studies focus on the use of mental health mobile apps (mHealth) in the hospital nurse population. Exploring interventions to mitigate negative responses to nurse-specific demands and stressors can inform how to help improve the mental health of the nursing workforce³. Improving nurses’ mental health may have a positive effect on …

Charge Acceleration Without Radiation, Yakir Aharonov, D. Collins, S. Popescu

Mathematics, Physics, and Computer Science Faculty Articles and Research

The existence of electromagnetic radiation—radio waves, microwaves, light, X-rays, and so on—is one of the most important physical phenomena, and our ability to manipulate them is one of the most significant technological achievement of humankind. Underlying this ability is our understanding of how radiation is produced: Whenever an electric charge is accelerated, it radiates. Or, at least, this is how it has been hitherto universally thought. Here, we prove that quantum mechanically electric charges can be accelerated without radiating. The physical setup leading to this behavior is relatively simple (once one knows what to do), but its reasons are deep: …

Pinterest’S Architecture And Algorithm, Aly Kellett

Comm-entary

Aly Kellett is a sophomore Communication major with a minor in Business Administration. Originally from Lynnfield, Massachusetts, she currently resides in Georgetown, MA. Aly is a radio host for WUNH, where she contributes to News at Nine, a program featuring guest speakers and discussions on meaningful topics. In her free time, she enjoys listening to music, playing pickleball, and shopping with friends.

This piece looks at how Pinterest’s San Francisco headquarters and digital platform communicate the company’s identity. It explains how the renovated building, central atrium, and knitting stairs create a sense of openness, collaboration, and creativity. The essay also …

No. 112 An Order Amending Executive Order 87 Regarding The Governor's Council For Judicial Appointments, Bill Lee

Executive Orders

No abstract provided.

No. 112 An Order Amending Executive Order 87 Regarding The Governor's Council For Judicial Appointments, Bill Lee

Executive Orders

No abstract provided.

A Mechanistic Model Of The Wash Shuffle And Monte Carlo Exploration Of Its Impact On Card Shuffling In Texas Hold’Em, Michael A. Alexeev, Peter B. Chi

UNLV Gaming Research & Review Journal

In casino games using a standard deck of cards, a wash shuffle is sometimes performed prior to the rest of the card shuffling procedure. Unlike other methods of shuffling, the wash shuffle has not yet been well studied. To this end, we first develop a mechanistic model of the wash shuffle based on our observation of how cards tend to move when a wash shuffle is being performed. Then, we use this model to simulate the card shuffling procedure used in casino poker rooms, and explore the resulting impact on where the cards are dealt in the context of Texas …

Rmzyme: Regulations Of Rna-Modifying Enzymes In Humans, Ruihan Luo, Haixia Xu, Qingbo Zhou, Shanli Ding, Min Qiang, Jianguo Wen, Pora Kim, Xiaojuan Yang, Yunshi Cai, Kunlin Xie, Jiang Zhu, Yungang Xu, Tian Lan, Xiaobo Zhou, Hong Wu

Faculty, Staff and Student Publications

RNA modifications represent a dynamic layer of gene expression regulation, RNA stability, and translation with profound implications for cellular function and disease. However, the critical regulation and functions of RNA-modifying proteins (RMPs) remain poorly understood. Here, we present a large-scale characterization of RMPs through 378 multiomics datasets encompassing genomics, bulk and single-cell transcriptomics, epitranscriptomics, proteomics, and posttranslational modifications (PTMs) across 63 human tissues. Our analysis of experimental perturbations of RMPs revealed dynamic differential modification peaks and expressed genes. We applied nonnegative matrix factorization to annotate RMP-mediated cell types in single-cell transcriptomes. Functional annotations in acute myeloid leukemia (AML) revealed RMPs …

Pace O Matic Inc V. Eckert Seamans Cherin & Mellott Llc

2026 Decisions

USDC for the Middle District of Pennsylvania

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

Francisco Merino-Angel V. Attorney General United States Of America

2026 Decisions

Agency

Who Lets Ai Take Over? Cross-National Variation In Willingness To Delegate Socially Important Roles To Artificial Intelligence, Ala Yankouskaya, Mohamed Basel Almourad, Magnus Liebherr, Fahad Beyahi, Guandong Xu, Raian Ali

All Works

Delegating socially significant roles to artificial intelligence (AI) is an emerging reality, yet little is known about how publics evaluate this transfer of responsibility across contexts and countries. This study applied a structural model to a large cross-national dataset (30,994 individuals in 35 countries) to test how cognitive appraisals, affective dispositions, and contextual factors jointly shape willingness to delegate socially important roles of companionship, mental health advisor, doctor and teacher to children to AI. The results revealed a robust hierarchy of delegation preferences, with companionship most frequently entrusted to AI, followed by mental-health advisor, teacher, and doctor. Cognitive appraisals emerged …

Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte

Faculty Publications

Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …

Effective Wordle Heuristics, Ronald I. Greenberg

Computer Science: Faculty Publications and Other Works

While previous researchers have performed an exhaustive search to determine an optimal Wordle strategy, that computation is very time consuming and produced a strategy using words that are unfamiliar to most people. With Wordle solutions being gradually eliminated (with a new puzzle each day and no reuse), an improved strategy could be generated each day, but the computation time makes a daily exhaustive search impractical. This paper shows that simple heuristics allow for fast generation of effective strategies and that little is lost by guessing only words that are possible solution words rather than more obscure words.

Emerging Threats In Ai: A Detailed Review Of Misuses And Risks Across Modern Ai Technologies, Niyat Seghid, Farkhund Iqbal, Khalifa Al-Room, Áine Macdermott

All Works

The swift evolution of artificial intelligence (AI) has enabled unprecedented capabilities across domains, while simultaneously introducing critical vulnerabilities that can be maliciously exploited or cause unintended harm. Although multiple initiatives aim to govern AI-related risks, a comprehensive and systematic understanding of how AI systems are actively misused in practice remains limited. This paper presents a systematic review of AI misuse across modern AI technologies. We analyze documented incidents, attack mechanisms, and emerging threat vectors, drawing from existing AI risk repositories, prior taxonomies, and empirical case reports. These sources are synthesized into a unified analytical framework that categorizes AI misuse across …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Predictive Accuracy Of Hill-Rbf 3.0 Versus Other Intraocular Lens Power Calculation Methods: Systematic Review And Meta-Analysis, Xiaole Li, Ronald Cheung, Manav Nayeni, Salem Abu Al-Burak, Prisha Dave, Bo Li, Monali S. Malvankar-Mehta

Student Publications

Objective: Amid growing adoption of AI in ophthalmology, Hill-Radial Basis Function (Hill-RBF) 3.0 formula may improve refractive target prediction across diverse populations, transforming patient care. This systematic review and meta-analysis (PROSPERO: CRD42021231150) evaluated the predictive performance of the Hill-RBF 3.0 against other traditional and AI-based intraocular lens (IOL) power calculation formulas.

Design: Systematic review and meta-analysis.

Methods: EMBASE, MEDLINE, CINAHL, and Web of Science were searched on March 17, 2025. Eligible studies reported refractive or cataract surgeries using Hill-RBF 3.0 and at least 1 comparable formula (Barrett Universal II, EVO 2.0, Haigis, Hoffer Q, Hoffer QST, Holladay I, Ladas Super …

Small Patients, Big Gaps: Why Adult Crrt Timing Evidence Does Not Translate To Children, Katja M Gist, Dana Y Fuhrman, Ayse Akcan-Arikan

Faculty, Staff and Students Publications

No abstract provided.

Spartan Daily, February 12, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 10

Targeting Oxalate Production By Combining Enzyme Inhibition And Proteolysis Activation: A Novel Therapeutic Approach For Primary Hyperoxaluria Type 1, Fabio Arias, Sumati Rohilla, Yudibeth Sixto-López, Koral S E Richard, Sandeep Das, Sumit K Anand, Pilar Maria Luque-Navarro, Guillermo Bañuelos-Sanchez, Juan Luis Pacheco-García, Reethika Gade, M Peyton Mckinney, Dhananjay Kumar, Jemiah Maxie, W Rylan Corr, Nilesh Pandey, Harpreet Kaur, Jibin Ding, Lin Tan, Elisha Scott, Hyung Nam, Eyal Gottlieb, A Wayne Orr, Nirav Dhanesha, Arif Yurdagul, Angel L Pey, Francisco Franco-Montalbán, José A Gómez Vidal, Oren Rom, Mónica Díaz-Gavilán

Faculty, Staff and Student Publications

Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder caused by hepatic oxalate overproduction due to alanine-glyoxylate aminotransferase (AGXT) deficiency. Therapeutic strategies targeting glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), key enzymes in glyoxylate metabolism, have shown promise in reducing oxalate burden. However, recently approved siRNA therapies remain limited by high cost, unfavorable pharmacokinetics, and limited global accessibility. We report the development of compound 2, a dual GO/LDHA inhibitor (K i = 390 and 40 nM, respectively) that also promotes hydrophobic tag-mediated autophagic degradation of LDHA. Its efficacy was evaluated in Agxt –/– mice, both in primary …

Serial False Lumen Patency Evaluation Of A Type B Dissection Represented With Malperfusion Following Medical Management, S Taha Zaidi, Quang Le, Firas Mussa, Akiko Tanaka, S Keisin Wang, Arash Keyhani, Kourosh Keyhani

Faculty, Staff and Student Publications

False lumen evolution in type B aortic dissection, particularly with medical management and anticoagulation, remains incompletely understood. We report a 55-year-old man on apixaban for pulmonary embolism with a subacute zone 3-10L TBAD without malperfusion. He was managed medically initially and represented twice over 2 months with back pain and acute right lower extremity ischemia. Serial imaging demonstrated dynamic remodeling with progression from partial to near-complete thrombosis to full reperfusion with true lumen compression. Urgent endovascular repair was performed successfully. This case illustrates the unpredictable course of medically managed TBAD and need for judicious use of anticoagulation.

Primary Tumor Size And Tumor-Vessel Interface Following Capecitabine And Temozolomide For Pancreatic Neuroendocrine Tumor, Jin Guo, Kever A Lewis, Laura Prakash, Priya Bhosale, Ajaykumar Morani, Matthew H G Katz, Ching-Wei D Tzeng, Naruhiko Ikoma, Rebecca Snyder, Michael P Kim, Chandrikha Chandrasekharan, Arvind Dasari, James C Yao, Jeffrey E Lee, Jessica E Maxwell, Daniel M Halperin

Faculty, Staff and Student Publications

Capecitabine/temozolomide (CAPTEM) is an established regimen for patients with metastatic pancreatic neuroendocrine tumors (PanNET) that is being increasingly used for tumor volume reduction in patients with borderline anatomically resectable disease. We sought to understand the response of the primary tumor, defined as changes in the tumor–vascular interface (TVI). This is a retrospective, single-institution study of patients with locally advanced or metastatic PanNET treated with CAPTEM between 2010 and 2020. RECISTv1.1 measurements and TVI assessments of the primary tumor were performed on pre- and post-therapy images. Patients with locally advanced or metastatic PanNET at presentation (n = 47) were included. …

Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yang Cai, Yu Ren, Hao Yuan, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li

Faculty, Staff and Student Publications

Cancer-induced cachexia and anorexia are debilitating complications across many cancers, yet effective treatments remain limited due to a poor understanding of the underlying mechanisms. Here, we identify an uncharacterized tumor-immune-neural circuit driving these syndromes, centered on growth and differentiation factor 15 (GDF15). Using genetically engineered mouse models, we find that loss of GDF15 protects against appetite loss, muscle wasting, and fat loss in pancreatic, lung, and skin cancers. Single-cell RNA sequencing reveals macrophages as a major source of GDF15, induced by tumor-derived colony-stimulating factor 1 (CSF1). GDF15 acts via the central nervous system to enhance β-adrenergic signaling in the tumor …

Weight Loss Patterns And Clinical Outcomes Of Glp1 Receptor Agonists In Breast Cancer Survivors, Jasmine S Sukumar, Akshara Singareeka Raghavendra, Sarah Pasyar, Roland L Bassett, Debu Tripathy, Carlos H Barcenas, Karen M Basen-Engquist, Banu K Arun

Faculty, Staff and Student Publications

Use of glucagon-like peptide-1 receptor agonists (GLP1-RA) for weight loss is increasing; implications in breast cancer (BC) survivors remain unclear.This retrospective cohort study evaluated treatment patterns, weight loss, and outcomes in BC survivors at an academic institution receiving GLP1-RA. We evaluated patients with non-metastatic (ductal carcinoma in situ (DCIS), stage 1-3) BC who received GLP1-RA (2005 - 2024). Linear regression models estimated associations between weight change and clinical factors. After excluding DCIS, propensity score matching (1:2) was used to match patients who received GLP1-RA with patients who did not, based on confounding covariates. Kaplan-Meier estimates and log-rank tests compared disease-free …

Artificial Intelligence In The Prosecution Of International Crimes, Marta Bo

International Law Studies

International criminal prosecutions face growing evidentiary challenges due to the vast and heterogeneous digital material generated during conflicts, including user-generated videos, social media, and intercepted communications. This article examines the potential role of artificial intelligence (AI) in supporting investigations and trials before the International Criminal Court (ICC). Rather than replacing judicial decision-making, AI can assist with specific tasks, particularly in establishing contextual elements and linkage evidence central to international crimes. The article explores three main areas: AI-driven biometric tools for facial and speech recognition; AI techniques for detecting patterns of violence and mapping command structures; and applications during trial proceedings, …

Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist

Department of Agricultural Economics Faculty Publications

Public stockholding of food is politically contentious and economically challenging. Although private stocks are generally understood to be more efficient than public stocks at providing a reliable buffer against production shortfalls, private stocks often fail to stabilize prices during extreme food market shocks. Moreover, maintaining large public stock programs in which the government acts as the buyer or seller of last resort, can be very costly. This paper analyzes the recent historical success of public and private rice stocks in stabilizing domestic rice prices in the Philippines, the world’s largest net importer of rice. Relying on competitive storage theory and …

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

February 12, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier

All Current Publications

This fact sheet provides women with basic information about perimenopause, menopause, and postmenopause, along with helpful tips and resources to better prepare for or manage these phases of life.