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Full-Text Articles in Entire DC Network

Contrast-Associated Acute Kidney Injury After Thrombectomy For Ischemic Stroke: Prognostic Impact And Can-Rest Predictive Score, Ghil Schwarz, Angelo Cascio Rizzo, Gareth Ambler, Pawel Wrona, Agnieszka Slowik, Szymonn Kotas, Mohamed F. Doheim, Alhamza R. Al-Bayati, Raul G. Nogueira, Ameer E. Hassan, Samantha Miller Mar 2026

Contrast-Associated Acute Kidney Injury After Thrombectomy For Ischemic Stroke: Prognostic Impact And Can-Rest Predictive Score, Ghil Schwarz, Angelo Cascio Rizzo, Gareth Ambler, Pawel Wrona, Agnieszka Slowik, Szymonn Kotas, Mohamed F. Doheim, Alhamza R. Al-Bayati, Raul G. Nogueira, Ameer E. Hassan, Samantha Miller

School of Medicine Publications

Background and objectives: Contrast-associated acute kidney injury (CA-AKI) is a potentially preventable complication after exposure to iodinated contrast media. In patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke (AIS), the incidence and clinical impact are poorly characterized, and no validated prediction tool is currently available. The aim of this study was to assess the incidence and prognostic significance of CA-AKI in EVT-treated patients with AIS and to develop and validate a predictive score.

Methods: A retrospective, multicenter cohort study was conducted involving EVT-treated patients across 73 centers in 16 countries (January-December 2023). Inclusion criteria were age ≥18 years, absence …


Lindenwood Broadcaster Earns Award Of Excellence, Truman Griessel Mar 2026

Lindenwood Broadcaster Earns Award Of Excellence, Truman Griessel

Lindenlink (2012- )

No abstract provided.


Fecal Carbohydrate-Degrading Bacteria Are Associated With Reduced Incidence Of Lower Gastrointestinal Gvhd, Christopher Fan, Tomo Hayase, Chia-Chi Chang, Israel K Glover, Ivonne I Flores, Miriam R Ortega, Rawan K El-Himri, Alexandria N Brown, Jennifer L Karmouch, Mohamed A Jamal, Saira S Ahmed, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Ashish Damania, Nadim J Ajami, Jennifer A Wargo, Christine B Peterson, Gabriela Rondon, Taha Al-Juhaishi, Amin M Alousi, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Eric Martens, Cesar A Arias, Robert R Jenq, Eiko Hayase Mar 2026

Fecal Carbohydrate-Degrading Bacteria Are Associated With Reduced Incidence Of Lower Gastrointestinal Gvhd, Christopher Fan, Tomo Hayase, Chia-Chi Chang, Israel K Glover, Ivonne I Flores, Miriam R Ortega, Rawan K El-Himri, Alexandria N Brown, Jennifer L Karmouch, Mohamed A Jamal, Saira S Ahmed, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Ashish Damania, Nadim J Ajami, Jennifer A Wargo, Christine B Peterson, Gabriela Rondon, Taha Al-Juhaishi, Amin M Alousi, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Eric Martens, Cesar A Arias, Robert R Jenq, Eiko Hayase

Faculty, Staff and Student Publications

Lower gastrointestinal graft-versus-host disease (LGI-GVHD) carries morbidity and mortality for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), with critical contributions from the intestinal microbiome. In a retrospective cohort of metagenomic sequencing of stool from patients with allo-HSCT (N = 90), we found that a reduction in specific Parabacteroides and Bacteroides species around the time of engraftment contributes to LGI-GVHD risk. Given the known diverse carbohydrate-degrading functionality of these bacteria, we investigated gene abundances for carbohydrate-active enzymes (CAZymes) and found that Parabacteroides merdae, P distasonis, and Bacteroides ovatus abundances were significantly correlated with CAZymes in patients who did not develop …


Genome-Wide Crispr Screen Identifies A Cytokine-Enhancer Circuit Driving Hif-2Α Activation In Renal Cancer, Jun Fang, Jeremy M Simon, Tao Wang, Yunpeng Gao, Xianju Bi, Chengheng Liao, Yayoi Adachi, Jin Zhou, Hongyi Liu, Qian Liang, James A Nathan, Ram Mani, James Brugarolas, Qing Zhang Mar 2026

Genome-Wide Crispr Screen Identifies A Cytokine-Enhancer Circuit Driving Hif-2Α Activation In Renal Cancer, Jun Fang, Jeremy M Simon, Tao Wang, Yunpeng Gao, Xianju Bi, Chengheng Liao, Yayoi Adachi, Jin Zhou, Hongyi Liu, Qian Liang, James A Nathan, Ram Mani, James Brugarolas, Qing Zhang

Faculty, Staff and Student Publications

Resistance to HIF-2α inhibitors such as Belzutifan underscores the need to better understand how HIF-2α is transcriptionally regulated in clear cell renal cell carcinoma (ccRCC). Here, we uncover a cytokine-driven enhancer mechanism that sustains HIF-2α expression through the JAK1-STAT3 signaling pathway. Using a genome-wide CRISPR screen in VHL-deficient ccRCC cells, we identified SOCS3 as a key negative regulator of HIF-2α. Mechanistically, loss of SOCS3 activates JAK1-STAT3 signaling, leading to the recruitment of STAT3 to distal enhancers upstream of EPAS1 that physically loop to its promoter to drive HIF-2α transcription. This cytokine-enhancer circuit was recapitulated in ccRCC patient samples and functionally …


A Cross-Sectional Survey On Hpv Vaccination In A Houston Hiv Clinic, Shailee R Modi, Erika S Fanous, Avery N Sinnathamby, Laura O Van Buskirk, Jason L Holliday, J Brooks Jackson, Mary B Rysavy Mar 2026

A Cross-Sectional Survey On Hpv Vaccination In A Houston Hiv Clinic, Shailee R Modi, Erika S Fanous, Avery N Sinnathamby, Laura O Van Buskirk, Jason L Holliday, J Brooks Jackson, Mary B Rysavy

Faculty, Staff and Student Publications

Background/Objectives: Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and causes cervical cancer in women. Patients with human immunodeficiency virus (HIV) are particularly susceptible to this virus. An effective vaccine against high-risk HPV genotypes is available. This study sought to evaluate barriers to HPV vaccination in HIV-positive female patients between the ages of 18 and 65 in a county clinic in Houston.

Methods: A cross-sectional survey was conducted in May-June 2025 with 131 patients at Thomas Street Health Center in Houston. The survey assessed patient demographics, attitudes toward and knowledge of HPV vaccination (at least one dose), …


Cdj-Pontryagin Optimal Control For General Continuously Monitored Quantum Systems, Tathagata Karmakar, Andrew N. Jordan Mar 2026

Cdj-Pontryagin Optimal Control For General Continuously Monitored Quantum Systems, Tathagata Karmakar, Andrew N. Jordan

Mathematics, Physics, and Computer Science Faculty Articles and Research

The Chantasri-Dressel-Jordan (CDJ) stochastic path integral formalism (Chantasri et al. 2013 and 2015) characterizes the statistics of the readouts and the most likely conditional evolution of continuously monitored quantum systems involving a few qubits or quantum harmonic oscillators in Gaussian states. In our work, we generalize the CDJ formalism to arbitrary continuously monitored systems by introducing a costate operator. We then prescribe a generalized Pontryagin's maximum principle for quantum systems undergoing arbitrary evolution and find conditions on optimal control protocols. We show that the CDJ formalism's most likely path can be cast as a quantum Pontryagin's maximum principle, where the …


Logic Model Development Through A Feasibility Rct For A Group-Based Weight Management Programme, Rod Sheaff, Shokraneh Moghadam, Laura Hollands, Lily Hawkins, Dawn Swancutt, Jenny Lloyd, Jonathan Pinkney, Mark Tarrant Mar 2026

Logic Model Development Through A Feasibility Rct For A Group-Based Weight Management Programme, Rod Sheaff, Shokraneh Moghadam, Laura Hollands, Lily Hawkins, Dawn Swancutt, Jenny Lloyd, Jonathan Pinkney, Mark Tarrant

School of Psychology

ObjectivesClinical psychology interventions for reducing obesity have developed alongside pharmacological and surgical treatments, but usually as interventions for individual patients. Any healthcare intervention rests on a logic model: assumptions that through specific physical and social mechanisms, it will produce certain intended outcomes, provided that conducive background conditions (‘contexts’) exist. Using evidence from the feasibility trial preceding a full randomised controlled trial (RCT), this paper assesses the empirical validity of the initial logic model of a new group-based weight management intervention: PROGROUP, designed for patients with body mass index (BMI) ≥40 kg/m2 or ≥35 kg/m2 with comorbidities. We aimed to test …


Geometry-Driven Controls On Hydrothermal Natural Hydrogen Generation From Magnetite Mineral, Kaveh Moghanirahimi, Lionel Esteban, Valeriya Shulakova, Muhammad Ali, Stefan Iglauer, Alireza Keshavarz Mar 2026

Geometry-Driven Controls On Hydrothermal Natural Hydrogen Generation From Magnetite Mineral, Kaveh Moghanirahimi, Lionel Esteban, Valeriya Shulakova, Muhammad Ali, Stefan Iglauer, Alireza Keshavarz

Research outputs 2022 to 2026

Despite recent efforts to investigate hydrothermal natural hydrogen production from magnetite, the effects of sample geometry and surface area on hydrogen yields remain inadequately characterized. This study compares hydrogen production from natural magnetite prepared as an intact slab versus fine powder under identical experimental conditions (pH 9, 200 °C, 103.4 bar, 60 days). The results show that magnetite powder yielded 0.052 mmol g−1 rock hydrogen, approximately fivefold higher than the slab. Comprehensive characterization of the magnetite slab revealed increased surface roughness after reaction. Quantitative XRD analysis showed substantial phase conversion from magnetite to hematite, consistent with oxidation of Fe2+ to …


A Letter To The Future, Derek Schuurman Mar 2026

A Letter To The Future, Derek Schuurman

University Faculty Publications and Creative Works

In 2100, our technology will be different, but our basic questions about life, meaning and evil will remain unchanged.


Marine Vehicle Dynamics Using Koopman Operator Theory With Hybrid Observables, Mikhalib A L Green Mar 2026

Marine Vehicle Dynamics Using Koopman Operator Theory With Hybrid Observables, Mikhalib A L Green

LSU Master's Theses

Accurate modeling of marine vehicle dynamics remains challenging due to strong nonlinear hydrodynamic effects, environmental disturbances, and sensitivity to configuration changes, particularly for small-scale platforms. Classical physics-based models require extensive parameter identification and often exhibit degraded performance outside narrow operating regimes, while purely data-driven approaches may lack structure or impose high computational cost. This thesis presents a data-driven Koopman operator framework with hybrid observables for modeling the dynamics of unmanned marine vehicles. The proposed approach combines structured monomial observables with a learned neural network embedding to construct a lifted state representation in which the nonlinear vehicle dynamics are approximated by …


Large-Scale File Fragment Classification Via Multi-View Learning, Samuel Hildebrand Mar 2026

Large-Scale File Fragment Classification Via Multi-View Learning, Samuel Hildebrand

LSU Master's Theses

File reassembly is one of the most fundamental tasks in digital forensics, enabling recovery of data from potentially damaged storage media even when file system metadata is unavailable. This thesis reviews more than two decades of work in the realm of file carving, with a particular focus on fragmented file carving, which remains a focus of research, and file fragment classification, a principal component of fragmented file carving. This thesis serves a literature review of both file carving and fragmented file carving, surveys the massive amounts of data needed for the task of fragment classification and the datasets that serve …


Sex And Gender Bias In Major Trauma Care: A Scoping Review, A. Ghika-Nanchen, L. Marzorati, A. Merra, C. Girardello, P. Truong, P. N. Carron, T. Nutbeam, C. Clair, F. X. Ageron Mar 2026

Sex And Gender Bias In Major Trauma Care: A Scoping Review, A. Ghika-Nanchen, L. Marzorati, A. Merra, C. Girardello, P. Truong, P. N. Carron, T. Nutbeam, C. Clair, F. X. Ageron

Peninsula Medical School

Background: Sex/gender bias have been well-documented in clinical medicine. However, few studies have assessed sex/gender disparities specifically in major trauma care. This scoping review aims to explore sex and gender-based differences in the emergency management of severely injured patients. Methods: A systematic literature review was conducted in the following electronic databases: Medline Ovid ALL, Embase, CINAHL with Full Text, Web of Science Core Collection, Cochrane Central Register of Controlled Trials with search criteria including keywords and mesh terms: gender, sex, major trauma, wounds and injuries. Three reviewers conducted the article selection. Results: Seventy-four full-text articles were included in the study. …


Bacillus Subtilis Parb C-Terminal Lysine Residues Are Essential For Dimerization And In Vivo Function, Indicating Their Roles In Dna Sliding, Aleksey Aleshintsev, Lindsey E. Way, Ngoc Khanh Lai, Bianca Guerra, Paloma Dorantes, Lois Akosua Serwaa, Sealtiel Anulao, Miranda Molina, Xindan Wang, Hyeongjun Kim Mar 2026

Bacillus Subtilis Parb C-Terminal Lysine Residues Are Essential For Dimerization And In Vivo Function, Indicating Their Roles In Dna Sliding, Aleksey Aleshintsev, Lindsey E. Way, Ngoc Khanh Lai, Bianca Guerra, Paloma Dorantes, Lois Akosua Serwaa, Sealtiel Anulao, Miranda Molina, Xindan Wang, Hyeongjun Kim

Physics & Astronomy Faculty Publications

The broadly conserved ParB protein performs crucial functions in bacterial chromosome segregation and replication regulation. The cellular function of ParB requires it to dimerize, recognize parS DNA sequences, clamp on DNA, then slide to adjacent sequences through nonspecific DNA binding. How ParB coordinates nonspecific DNA binding and sliding remains elusive. Here, we combine multiple in vitro biophysical and computational tools and in vivo approaches to address this question. We found that five conserved lysine residues in the C-terminal domain (CTD) of ParB play distinct roles. While the two central rigid lysine residues provide the structural platform for the CTD, the …


Heterogeneity And Plasticity Of The Naive Cd4+ T Cell Compartment, Mohamed Eltanbouly, Elizabeth C Nowak, Chao Cheng, Christopher M Burns, Mary Jo Turk, Randolph J Noelle, J Louise Lines Mar 2026

Heterogeneity And Plasticity Of The Naive Cd4+ T Cell Compartment, Mohamed Eltanbouly, Elizabeth C Nowak, Chao Cheng, Christopher M Burns, Mary Jo Turk, Randolph J Noelle, J Louise Lines

Faculty, Staff and Students Publications

This study describes the transcriptional heterogeneity of murine and human naive CD4+ T cells as comprising multiple discrete clusters that impact CD4+ T cell fate and trajectories. Naive CD4+ T cells experiencing inflammatory environments exhibit an altered transcriptional state that biases their differentiation trajectories.


Drug Procurement Methods And Challenges In Asian Low And Lower-Middle-Income Countries: A Systematic Review, Ferina Septiani Damanik, Anna Wahyuni Widayanti, Muhammad Qowiyul Amin Mar 2026

Drug Procurement Methods And Challenges In Asian Low And Lower-Middle-Income Countries: A Systematic Review, Ferina Septiani Damanik, Anna Wahyuni Widayanti, Muhammad Qowiyul Amin

The Thai Journal of Pharmaceutical Sciences

Background: Pharmaceutical procurement plays a pivotal role in healthcare within Asian low and lower-middle-income countries (LLMICs), ensuring accessibility to essential, cost-effective, and high-quality medicines. Tailored approaches are imperative due to specific challenges inherent in these countries.
Objectives: This review examines several drug procurement systems in Asian countries with LLMICs while identifying and evaluating any potential challenges that might arise within the systems.
Materials and Methods: This review using the preferred reporting items for systematic reviews and meta-analyses guidelines and three search engines (PubMed, Science Direct, and Research Gate) employing Boolean search terms. The search focuses on drug procurement, medicine procurement, …


Efficacy And Safety Of Stem Cell-Based Interventions For Burn Wound Healing: A Systematic Review And Meta-Analysis Of Pre-Clinical And Early Clinical Evidence, Prayuth Poowaruttanawiwit, Patsanan Kulla, Naveeya Pakpoomkamonlert Mar 2026

Efficacy And Safety Of Stem Cell-Based Interventions For Burn Wound Healing: A Systematic Review And Meta-Analysis Of Pre-Clinical And Early Clinical Evidence, Prayuth Poowaruttanawiwit, Patsanan Kulla, Naveeya Pakpoomkamonlert

The Thai Journal of Pharmaceutical Sciences

Background: Burn injuries remain a major therapeutic challenge, with conventional treatments often failing to achieve complete functional skin regeneration. Stem cell-based interventions, including mesenchymal stem cells (MSCs) and exosome derivatives, have demonstrated regenerative and immunomodulatory potential, yet their translation to clinical practice remains limited.
Objectives: To systematically evaluate the efficacy and safety of stem cell-based therapies for burn wound healing across pre-clinical and clinical studies.
Materials and Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, four databases (PubMed, Embase, Scopus, and Cochrane) were searched through April 2025. Eligible studies included randomized controlled trials and controlled pre-clinical …


Characteristics Of Drug-Related Problems And The Impact Of Pharmacist Interventions On Hospital Drug Costs In The Medical Intensive Care Unit, Sirima Sitaruno, Wanrada Binyala, Pattama Phetsuk, Nisrin Ni-Ngoh, Worakarn Nukong, Asama Saiwaree, Nawaporn Assanangkornchai, Tanatape Wanishayakorn Mar 2026

Characteristics Of Drug-Related Problems And The Impact Of Pharmacist Interventions On Hospital Drug Costs In The Medical Intensive Care Unit, Sirima Sitaruno, Wanrada Binyala, Pattama Phetsuk, Nisrin Ni-Ngoh, Worakarn Nukong, Asama Saiwaree, Nawaporn Assanangkornchai, Tanatape Wanishayakorn

The Thai Journal of Pharmaceutical Sciences

Background: Pharmaceutical care activities have been reported to enhance treatment outcomes and cost-effectiveness in critically ill patients. However, relevant and timely data on this topic are still lacking in Thailand.
Objectives: The objective of the study is to investigate the characteristics of drug-related problems (DRPs) identified during pharmaceutical care activities at the medical intensive care unit (MICU) of a tertiary care teaching hospital in Thailand. In addition, we aimed to quantify the impact of pharmacist interventions on hospital drug costs.
Materials and Methods: DRPs identified during pharmaceutical care activities over 3 years were reviewed and classified by the Pharmaceutical Care …


“I Think I Failed Them Again”: Exploring Perceived Signs Of Parental Disappointment And Its Impact On Adolescents’ Emotional Well-Being, Ixchel Rain V. Atienza, Jimmy Stephen A. Asuero, Szarina Anne S. De Guzman, Renee Mai Mar 2026

“I Think I Failed Them Again”: Exploring Perceived Signs Of Parental Disappointment And Its Impact On Adolescents’ Emotional Well-Being, Ixchel Rain V. Atienza, Jimmy Stephen A. Asuero, Szarina Anne S. De Guzman, Renee Mai

DLSU Senior High School Research Congress Conference Proceedings

Parental expectations significantly shape adolescents' emotional well-being and self-perception, especially in Philippine culture, where family honor and obligations are expected. Perceived parental disappointment can lead to emotional distress, anxiety, and self-doubt, affecting self-esteem and personal development. While much of the existing research focuses on parental perspectives, there is little research and understanding of how adolescents internalize these experiences. This study examines the narratives of Filipino adolescents on perceived parental disappointment, highlighting its emotional and psychological effects. This study utilized interviews in order to collect the lived experiences of Filipino adolescents aged 18-19, residing in Binan and Sta. Rosa, Laguna. Through …


Identification Accuracy Of Cost-Effective Visible (Vis) To Near-Infrared (Nir) Sensor As7265x On Plastic Waste In The Philippines, Ma. Tricia Jasmin M. Ocho, Chloe Lizanne R. Bravo, Jennika Love R. Loyola, Kierra Jamielle Velandria Taroma, Leianne Nina Arabelle E. Lampayan Mar 2026

Identification Accuracy Of Cost-Effective Visible (Vis) To Near-Infrared (Nir) Sensor As7265x On Plastic Waste In The Philippines, Ma. Tricia Jasmin M. Ocho, Chloe Lizanne R. Bravo, Jennika Love R. Loyola, Kierra Jamielle Velandria Taroma, Leianne Nina Arabelle E. Lampayan

DLSU Senior High School Research Congress Conference Proceedings

In the Philippines, plastic waste persists as a significant issue caused by the widespread use of single-use plastics and the lack of recycling systems. The lack of proper systems made waste segregation and identification inefficient and disorganized. Past studies explain the use of VIS/NIR in plastic segregation and the potential of spectral frequencies. However, there is limited investigation into the consistency of the AS7265x sensor to address reliability in real-world conditions, where contaminants, variable lighting, and material degradation significantly impact performance. Thus, the study evaluates the effectiveness of the AS7265x triad spectroscopy sensor, incorporating machine learning algorithms. An experimental setup …


Revisiting The Dk Gandhi Sc Judgment 2024 On The Liability Of Advocates Under The Consumer Protection Law, Jeet Singh Mann Mar 2026

Revisiting The Dk Gandhi Sc Judgment 2024 On The Liability Of Advocates Under The Consumer Protection Law, Jeet Singh Mann

International Journal on Consumer Law and Practice

A Division Bench of the Supreme Court in Bar of Indian Lawyers v DK Gandhi concluded on 14 May 2024 that advocates are covered by a contract of personal service; thereby, no professional negligence or deficiency in service by advocates can be said to arise under the Consumer Protection Act 1986/2019. The said judgment is per incuriam as it ignores fundamentals of the contract of service, the mandate, the scheme of social welfare legislation and consumer protection law, and judgments of larger benches on accountability of professionals, including advocates, for professional negligence. This article critically examines whether advocates are covered …


Development Of An Mhealth Application To Be Used In Assisting Caregivers, Samantha Lianne Lim Cheong, Sofia Margarita S. Cristobal, Precious Channe Esther S. Dioquino, Matteo G. Guanzon, Kyle Ian Jeffrey Lim Lim Mar 2026

Development Of An Mhealth Application To Be Used In Assisting Caregivers, Samantha Lianne Lim Cheong, Sofia Margarita S. Cristobal, Precious Channe Esther S. Dioquino, Matteo G. Guanzon, Kyle Ian Jeffrey Lim Lim

DLSU Senior High School Research Congress Conference Proceedings

Assistive technology refers to any product, device, or system that helps individuals with their care and aids with tasks that have become difficult due to physical, cognitive, or sensory limitations. Within the scope of assistive technology are mobile health (mHealth) applications, which utilize mobile devices to provide healthcare services and information. Due to the mHealth applications' implementations on mobile devices, their adaptability is universal and accessible. This research aims to develop a mHealth application that is primarily accessible and designed specifically for caregivers by using their recommendations as the main references alongside literature reviews. It explores the features of mHealth …


Iah-Net (Informative Air Quality And Heat Index Network): Drone-Assisted System For Real-Time Air Quality And Heat Index Monitoring, Brent Breo B. Magbanua Mar 2026

Iah-Net (Informative Air Quality And Heat Index Network): Drone-Assisted System For Real-Time Air Quality And Heat Index Monitoring, Brent Breo B. Magbanua

DLSU Senior High School Research Congress Conference Proceedings

Air pollution and rising temperatures threaten public health and safety, necessitating advanced monitoring solutions. This study developed a drone-assisted system for autonomous monitoring of air quality and heat index, ensuring real-time alerts even in the absence of human presence. By integrating the K-Nearest Neighbors (K-NN) machine learning algorithm, the system provides an innovative and cost-effective approach to identifying environmental risks and raising awareness. The system consists of a Drone system, ESP32, MQ-135 gas sensor, and DHT11 temperature and humidity sensor for data acquisition. Software development includes implementing the K-NN algorithm and calibrating sensors to enhance classification accuracy. The system categorizes …


Development Of “Defaketicon” An Educational Deepfake Awareness Website For Senior High School Stem-Technology Students, Killua Andrei S. Nava, Sofia Agatha D. Atienza, John Carlo A. Tan, Trisha Nicole E. Sese, Iyana Magdalene O. Montoya, Krizjof Myke B. Gaspar, Gio Angelo P. Garcia, Princess Angel E. Miraflores, Jann Bryanne S. Ashby, June Ray O. Filler, Juan Antonio D. Gulles, Laurence Andrew B. Marquez, Aledd Dwayne M. Valenzuela, Tony M. Dulay, Keith Andrew C. Mira Mar 2026

Development Of “Defaketicon” An Educational Deepfake Awareness Website For Senior High School Stem-Technology Students, Killua Andrei S. Nava, Sofia Agatha D. Atienza, John Carlo A. Tan, Trisha Nicole E. Sese, Iyana Magdalene O. Montoya, Krizjof Myke B. Gaspar, Gio Angelo P. Garcia, Princess Angel E. Miraflores, Jann Bryanne S. Ashby, June Ray O. Filler, Juan Antonio D. Gulles, Laurence Andrew B. Marquez, Aledd Dwayne M. Valenzuela, Tony M. Dulay, Keith Andrew C. Mira

DLSU Senior High School Research Congress Conference Proceedings

This study addresses the increasing threat of deepfake media by developing   “Defaketicon” an educational website designed to raise awareness among senior high school STEM Technology students at Adamson University. The primary objective is to evaluate the students’ perceptions of the website in terms of performance expectancy, effort expectancy, social influence, and facilitating conditions. Using a convergent mixed-method approach, the researchers conducted a non-experimental descriptive design for the quantitative data and a narrative inquiry for the qualitative aspect. A total of 117 students participated through simple random sampling, while 8 were purposively selected for in-depth qualitative analysis. Findings from the quantitative …


Optimization Of Solvent Extraction For Polyphenols And Antioxidant Activity From Zanthoxylum Acanthopodium Leaves Using Simplex Centroid Design, Waras Nurcholis, Indah Z. Septiawati, Roni Kartiman, Surya Diantina Mar 2026

Optimization Of Solvent Extraction For Polyphenols And Antioxidant Activity From Zanthoxylum Acanthopodium Leaves Using Simplex Centroid Design, Waras Nurcholis, Indah Z. Septiawati, Roni Kartiman, Surya Diantina

The Thai Journal of Pharmaceutical Sciences

Background: Zanthoxylum acanthopodium DC., locally known as andaliman, is an indigenous spice from North Sumatra, Indonesia, recognized for its high antioxidant potential. Despite its bioactive richness, optimization of solvent extraction for phenolic and flavonoid compounds from its leaves remains underexplored, even though these compounds are valuable for food and pharmaceutical applications. The use of solvents such as acetone in analytical extraction contexts is acceptable; however, further purification steps would be required for applications in food and pharmaceutical products.
Objectives: The main objective of this study was to optimize solvent combinations – comprising water, ethanol, and acetone – to maximize the …


Pharmacognostic Analysis And Thin-Layer Chromatographic Study Of The Thai Antipyretic Herbal Formula Khiao-Bencha-Khan, Sirinapa Chaisri, Tassanee Paraput, Pravit Akarasereenont, Pinpat Tripatara Mar 2026

Pharmacognostic Analysis And Thin-Layer Chromatographic Study Of The Thai Antipyretic Herbal Formula Khiao-Bencha-Khan, Sirinapa Chaisri, Tassanee Paraput, Pravit Akarasereenont, Pinpat Tripatara

The Thai Journal of Pharmaceutical Sciences

Background: Khiao-bencha-khan formula (KBF) is an herbal formula recorded in Thai scriptures and used to treat fever, including exanthematous fever, and aphthous ulcers. It consists of Limnophila rugosa (Roth) Merr., Bacopa monnieri (L.) Wettst., Gossypium arboreum L., Pogostemon cablin (Blanco) Benth., Eupatorium japonicum L., and Justicia gendarussa Burm.f.
Objectives: This study aimed to identify the pharmacognostic and chemical profiles of the herbal components found in KBF.
Methods: All authentic plant materials were collected, and samples were prepared under Pharmaceutical Inspection Co-operation Scheme/good manufacturing practice guidelines. The materials were identified using macroscopic, microscopic, and thin-layer chromatography (TLC) methods.
Results: Microscopic analysis …


Age And Susceptibility: The Impact Of Age On The Cyberattack Susceptibility Of Parañaque Citizens, Jana Dorathy P. Loyola, Clisha Rae V. Batangan, Carlos Jordan A. Datu, Joseph A. Espiritu, Roberto Romano G. Lim, Mark Kenneth D. Cabaccan Mar 2026

Age And Susceptibility: The Impact Of Age On The Cyberattack Susceptibility Of Parañaque Citizens, Jana Dorathy P. Loyola, Clisha Rae V. Batangan, Carlos Jordan A. Datu, Joseph A. Espiritu, Roberto Romano G. Lim, Mark Kenneth D. Cabaccan

DLSU Senior High School Research Congress Conference Proceedings

Throughout the years, multiple studies have been conducted to determine the impact of age on cybersecurity; however, their results were contradictory. To clarify the answer, this study examined how being a part of different age generations (Generation Z, Millennials, Generation X, and Baby Boomers) affects cybersecurity awareness, behavior, and susceptibility to cyberattacks among Parañaque citizens. The objective is to identify the susceptibility levels of each generation and to determine whether there is a significant difference between them. A total of 134 participants answered the questionnaire about their cybersecurity attitudes, knowledge, and practices. Using statistical tools such as General Weighted Mean …


Design Of Experiments Based Reversed-Phase High-Performance Liquid Chromatography Method For Estimation Of Metformin And Glimepiride In Combined Dosage Forms, Neela Manish Bhatia, Rachana Patil, Harinath More, Rutuja Dattatray Chougale Mar 2026

Design Of Experiments Based Reversed-Phase High-Performance Liquid Chromatography Method For Estimation Of Metformin And Glimepiride In Combined Dosage Forms, Neela Manish Bhatia, Rachana Patil, Harinath More, Rutuja Dattatray Chougale

The Thai Journal of Pharmaceutical Sciences

Background: The present study aimed to systematically develop and validate a robust, rapid, and stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of metformin and glimepiride in fixeddose combination tablets. Method development was guided by a design of experiments (DoE) approach using the Box-Behnken design (BBD) to ensure optimal analytical performance.
Materials and Methods: Chromatographic separation was achieved on a Cosmosil C18 column using an optimized mobile phase of acetonitrile and water (80:20, v/v) adjusted to pH 3.5. The flow rate was 1 mL/min, and detection was performed at 221 nm. The BBD approach systematically evaluated the …


Development Of Aqueous Dispersions Of Zein–Inulin Nanoparticles: Influence Of Formulation Variables On Physical Properties, Wanarat Sayamol, Supakarn Chamni, Jittima Chatchawalsaisin Mar 2026

Development Of Aqueous Dispersions Of Zein–Inulin Nanoparticles: Influence Of Formulation Variables On Physical Properties, Wanarat Sayamol, Supakarn Chamni, Jittima Chatchawalsaisin

The Thai Journal of Pharmaceutical Sciences

Background: Zein-based nanoparticles exhibit considerable potential for pharmaceutical and food applications. Incorporating inulin, a prebiotic polysaccharide, can improve their functional performance. Owing to the distinct solubilities of zein and inulin in aqueous ethanol, zein– inulin nanoparticles can be prepared through precipitation using their respective anti-solvents.
Objectives: This study aimed to systematically develop zein–inulin nanoparticles using the antisolvent precipitation method, with a focus on investigating the effects of formulation variables on particle characteristics and dispersion properties.
Materials and Methods: Zein–inulin nanoparticles were prepared using an anti-solvent precipitation method. Zein and inulin were separately dissolved in aqueous ethanol and water, respectively. The …


Medicines Security And Bioprospecting: A Future Agenda For Pharmaceutical Research, Geoffrey A. Cordell Mar 2026

Medicines Security And Bioprospecting: A Future Agenda For Pharmaceutical Research, Geoffrey A. Cordell

The Thai Journal of Pharmaceutical Sciences

Humanity is at an extraordinary moment in history, where our interwoven future in Gaia depends on showing reverence for the modulation of our resource limits after significant losses of biodiversity and encroaching environmental change, including disappearing glaciers, rising sea levels, and changing climates. Engaging with the interconnectedness of all life on Earth and integrating sustainability and optimization of the valuable, renewable resources for future generations are essential beginning actions. Fostering economic and resource sustainability deepens the focus for contemporary research priorities toward assuring access to biological agents needed by the consumer/patient. Based on the outcomes of the COP28/29/30 and COP15/16 …


Message From The Editor: Marking A Half Century Of Our Academic Contribution, Witchuda Thanakijcharoenpath Mar 2026

Message From The Editor: Marking A Half Century Of Our Academic Contribution, Witchuda Thanakijcharoenpath

The Thai Journal of Pharmaceutical Sciences

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