Digital Commons Network^™

Risk Factors Associated With Hospitalization And Death In Covid-19 Breakthrough Infections, Geehan Suleyman, Raef Fadel, Indira Brar, Rita Kassab, Rafa Khansa, Nicholas Sturla, Ayman Alsaadi, Katie Latack, Joseph B. Miller Md, Robert J. Tibbetts, Linoj Samuel, George Alangaden, Mayur Ramesh

Infectious Diseases Articles

BACKGROUND: Characterizations of coronavirus disease 2019 (COVID-19) vaccine breakthrough infections are limited. We aim to characterize breakthrough infections and identify risk factors associated with outcomes.

METHODS: This was a retrospective case series of consecutive fully vaccinated patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a multicenter academic center in Southeast Michigan, between December 30, 2020, and September 15, 2021.

RESULTS: A total of 982 patients were identified; the mean age was 57.9 years, 565 (59%) were female, 774 (79%) were White, and 255 (26%) were health care workers (HCWs). The median number of comorbidities was 2; 225 (23%) …

Hiv Virological Non-Suppression Is Highly Prevalent Among 18- To 24-Year-Old Youths On Antiretroviral Therapy At The Kenyan Coast, Moses K. Nyongesa, Mwaganyuma H. Mwatasa, Vincent A. Kagonya, Gabriel Mwambingu, Caroline Ngetsa, Charles R. J. C. Newton, Amina Abubakar

Institute for Human Development, East Africa

Background: In sub-Saharan Africa, data on virologic outcomes of young people living with HIV (YLWH) enrolled on antiretroviral therapy (ART) remains scarce. In this study, we describe the prevalence of HIV virological non-suppression (VNS) and its associated factors among YLWH aged 18–24 years from the Kenyan coast.

Methods: Data were analyzed for 384 YLWH who participated in a larger cross-sectional study conducted between November 2018 and September 2019 in two counties at the Kenyan coast (Kilif and Mombasa). Descriptive statistics were used to summarize sample characteristics and logistic regression was used for statistical modeling of factors associated with …

Adolescent Connectedness: A Scoping Review Of Available Measures And Their Psychometric Properties, Ezra Too, Esther Chongwo, Adam Mabrouk, Amina Abubakar

Institute for Human Development, East Africa

Introduction: Adolescent connectedness, a key component of positive youth development, is associated with various positive health outcomes. Several measures have been developed to assess this construct. However, no study has summarized data on the existing measures of adolescent connectedness. We conducted this scoping review to fill this gap. We specifically aimed to: (i) identify the existing measures of adolescent connectedness, (ii) determine the most frequently used measures among the identified measures, and (iii) summarize the psychometric properties of these measures with a keen interest in highlighting their cross-cultural utility and validity.

Methods: We searched CINAHL, Embase, PsycInfo, PubMed, …

May 2022 Newsletter

Ergo

No abstract provided.

Queer Representation In The Scream Franchise, Amber M. Harvey

Departmental Honors & Graduate Capstone Projects

This paper is an exploration of queer representation across the Scream film franchise. The original Scream premiered in 1996 and in 2022 and the series was rebooted with new characters that are the second generation of the characters in the first film. The direct parallels between the films allow for an analysis of how representation has grown with the times. The ultimate goal of this paper was to investigate two different aspects of on screen representation: quantity (how many queer characters are shown?) and quality (Are they queer coded? Are they shown to actually be queer? Do they embody queer …

Pride Before The Fall: A Historical Fiction Novel, Brenna Smith

Undergraduate University Honors Capstones

The Mycenaean civilization (1650 BCE-1200 BCE) was the first advanced Greek civilization with many features that characterized Classical Greece such as palace states, art, a writing system, intercultural contact, and more. The focus of this capstone project is the ancient Mycenaean civilization, particularly capturing both the build up to and the actual rise of the Greek Early Iron Age (1200 BCE-800 BCE) period, or the Greek Dark Ages. This project takes the form of a historical fiction novel which seeks to offer a possible explanation for how the collapse came to be, using archaeological evidence in partnership with creative writing. …

Methodology For Classification And Definition Of Epilepsy Syndromes With List Of Syndromes: Report Of The Ilae Task Force On Nosology And Definitions, Elaine C. Wirrell, Rima Nabbout, Ingrid E. Scheffer, Taoufik Alsaadi, Alicia Bogacz, Jacqueline A. French, Edouard Hirsch, Satish Jain, Sunao Kaneko, Pauline Samia

Paediatrics and Child Health, East Africa

Epilepsy syndromes have been recognized for >50 years, as distinct electroclini-cal phenotypes with therapeutic and prognostic implications. Nonetheless, noformally accepted International League Against Epilepsy (ILAE) classification ofepilepsy syndromes has existed. The ILAE Task Force on Nosology and Definitionswas established to reach consensus regarding which entities fulfilled criteria for anepilepsy syndrome and to provide definitions for each syndrome. We defined an ep-ilepsy syndrome as “a characteristic cluster of clinical and electroencephalographicfeatures, often supported by specific etiological findings (structural, genetic, met-abolic, immune, and infectious).” The diagnosis of a syndrome in an individualwith epilepsy frequently carries prognostic and treatment implications. Syndromesoften have age- …

Extracellular Vesicles Released After Cranial Radiation: An Insight Into An Early Mechanism Of Brain Injury., Suriyan Sukati, Jenni Ho, Luksana Chaiswing, Pradoldej Sompol, Harshul Pandit, Wendy Wei, Tadahide Izumi, Quan Chen, Heidi Weiss, Teresa Noel, Subbarao Bondada, D Allan Butterfield, Daret K St Clair

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Cranial radiation is important for treating both primary brain tumors and brain metastases. A potential delayed side effect of cranial radiation is neurocognitive function decline. Early detection of CNS injury might prevent further neuronal damage. Extracellular vesicles (EVs) have emerged as a potential diagnostic tool because of their unique membranous characteristics and cargos. We investigated whether EVs can be an early indicator of CNS injury by giving C57BJ/6 mice 10 Gy cranial IR. EVs were isolated from sera to quantify: 1) number of EVs using nanoparticle tracking analysis (NTA); 2) Glial fibrillary acidic protein (GFAP), an astrocyte marker; and 3) …

International League Against Epilepsy Classification And Definition Of Epilepsy Syndromes With Onset In Childhood: Position Paper By The Ilae Task Force On Nosology And Definitions, Nicola Specchio, Elaine C. Wirrell, Ingrid E. Scheffer, Rima Nabbout, Kate Riney, Pauline Samia, Marilisa Guerreiro, Sam Gwer, Sameer M. Zuberi, Jo M. Wilmshurs

Paediatrics and Child Health, East Africa

The 2017 International League Against Epilepsy classification has defined a three- tiersystem with epilepsy syndrome identification at the third level. Although a syndromecannot be determined in all children with epilepsy, identification of a specific syn-drome provides guidance on management and prognosis. In this paper, we describethe childhood onset epilepsy syndromes, most of which have both mandatory seizuretype(s) and interictal electroencephalographic (EEG) features. Based on the 2017Classification of Seizures and Epilepsies, some syndrome names have been updatedusing terms directly describing the seizure semiology. Epilepsy syndromes beginningin childhood have been divided into three categories: (1) self- limited focal epilepsies,comprising four syndromes: self- …

Preoperative And Postoperative Patient-Reported Outcome Measurement Information System Scores In Patients Treated For Benign Versus Malignant Soft Tissue Tumors, Jonathan F. Dalton, Ryan Furdock, Landon Cluts, Bharadwaj Jilakara, Douglas Mcdonald, Ryan Calfee, Cara Cipriano

Open Access Publications

BACKGROUND: The Patient-Reported Outcomes Measurement Information System (PROMIS) assesses multiple aspects of patient well-being but has not been thoroughly studied amongst orthopedic oncology patients.

QUESTIONS/PURPOSES: How do preoperative/early postoperative PROMIS scores compare in patients with benign versus malignant soft tissue tumors (STTs) for (1) physical function, (2) pain interference, and (3) depression? Are the differences clinically relevant? What other patient/tumor factors impact PROMIS?

METHODS: This retrospective cohort study included 314 STT patients who underwent resection of a benign (n = 187) or malignant (n = 127) STT over a period of 4.25 years at a single institution. PROMIS physical function, …

A Community-Based Approach To Cervical Cancer Prevention In Western Kenya: An Ampath Feasibility Project, Elkanah Omenge, Philip Tonui, Kapten Muthoka, Stephen Kiptoo, Titus Maina, Mercy Agosa, Aaron Ermel, Yan Tong, Darron Brown

Obstetrics and Gynaecology, East Africa

Objectives: Centralized programs have been ineffective in reducing the burden of cervical cancer among Kenyan women. A community-based pilot study was initiated to screen Kenyan women for cervical cancer and to vaccinate their children against human papillomavirus (HPV).

Methods: Women were educated about cervical cancer prevention at community meetings. Women then provided self-collected vaginal swabs for oncogenic HPV testing using the Roche Cobas Assay. All women were then referred to the local clinic for Visual Inspection with Acetic Acid (VIA). Women were offered the quadrivalent HPV vaccine for their children if and when it became available for the …

University Education Model: Socialisation Report 2022, Shaun Ferns, Barry J. Ryan, Fionnuala Darby

Group Reports

The UEM Socialisation Report provides an in-depth analysis of the early-stage engagement with the University Education Model (UEM) at TU Dublin, exploring how key stakeholders—including staff, students, and external partners—interpret and apply its 10 Guiding Principles. The report draws on inputs from 32 online events involving 235 participants, analysing the thematic contributions to identify four emergent themes: Connected, Learner-Centred, TU Dublin Enablers, and Graduate Employability. These themes, aligned with Sustainable Development Goal 4 (Quality Education), highlight the need for an inclusive, student-focused, and flexible education model that enhances employability and fosters a sense of belonging. The findings will inform the …

Studying Acetylation Of Aconitase Isozymes By Genetic Code Expansion, Jessica Araujo

Graduate Theses and Dissertations

The tricarboxylic acid (TCA) cycle is a very important, centrally located, energy-producing pathway that connects numerous other metabolic and regulatory pathways. Enzymes of this cycle have been more recently implicated in various cancers and neurometabolic disorders, however, the exact mechanism by which this happens becomes quite complex when considering the potential modification of these enzymes and the presence of multiple forms of the enzymes and therefore there is much to be studied in this area.

Aconitase has become a recent enzyme of interest as its substrate, citrate, has been found to play a major role in many vital processes within …

Speaking The Truth In Love, Nicholas Miller

Lake Union Herald

No abstract provided.

Imparting A Knowledge Of God, Linda Fuchs, Ruth Horton

Lake Union Herald

No abstract provided.

Embedding ‘Holistic Intelligence’ Education At Tu Dublin, Fionnuala Darby, Shaun Ferns, Barry J. Ryan

Group Reports

This document outlines the integration of Holistic Intelligence (HI) education within Technological University Dublin’s (TU Dublin) University Education Model (UEM). Holistic Intelligence education aims to foster a culture of well-being and productivity by addressing eight dimensions: personal, social, occupational, physical, economic, intellectual, emotional, and environmental. The document emphasises the importance of embedding HI education into the curriculum to support transformative learning experiences and align with TU Dublin’s strategic intent. It discusses the principles and enablers of HI education and highlights the benefits of HI education for learners, staff, and the community.

The Dense Gas Mass Fraction And The Relationship To Star Formation In M51, Mark Heyer, Benjamin Gregg, Daniela Calzetti, Bruce G. Elmegreen, Robert Kennicutt, Angela Adamo, Aaron S. Evans, Kathryn Grasha, James D. Lowenthal, Gopal Narayanan, Daniel Rosa-Gonzalez, F. P. Schloerb, Kamal Souccar, Yuping Tang, Peter Teuben, Olga Vega, William F. Wall, Min S. Yun

Astronomy: Faculty Publications

Observations of 12CO J = 1 - 0 and HCN J = 1 - 0 emission from NGC 5194 (M51) made with the 50 m Large Millimeter Telescope and the SEQUOIA focal plane array are presented. Using the HCN-to-CO ratio, we examine the dense gas mass fraction over a range of environmental conditions within the galaxy. Within the disk, the dense gas mass fraction varies along the spiral arms but the average value over all spiral arms is comparable to the mean value of interarm regions. We suggest that the near-constant dense gas mass fraction throughout the disk arises from …

Alma Discovery Of A Disk Around The Planetary-Mass Companion Sr 12 C, Ya Lin Wu, Brendan P. Bowler, Patrick D. Sheehan, Laird M. Close, Joshua A. Eisner, William M.J. Best, Kimberly Ward-Duong, Zhaohuan Zhu, Adam L. Kraus

Astronomy: Faculty Publications

We report an Atacama Large Millimeter/submillimeter Array 0.88 mm (Band 7) continuum detection of the accretion disk around SR 12 c, an ∼11 M Jup planetary-mass companion (PMC) orbiting its host binary at 980 au. This is the first submillimeter detection of a circumplanetary disk around a wide PMC. The disk has a flux density of 127 ± 14 μJy and is not resolved by the ∼0.″1 beam, so the dust disk radius is likely less than 5 au and can be much smaller if the dust continuum is optically thick. If, however, the dust emission is optically thin, then …

Polarizations Of Powers Of Graded Maximal Ideals, Ayah Almousa, Gunnar Fløystad, Henning Lohne

Mathematics Faculty Publications

We give a complete combinatorial characterization of all possible polarizations of powers of the graded maximal ideal (x₁,x₂,…,x_m)ⁿ of a polynomial ring in m variables. We also give a combinatorial description of the Alexander duals of such polarizations. In the three variable case m=3 and also in the power two case n=2 the descriptions are easily visualized and we show that every polarization defines a (shellable) simplicial ball. We give conjectures relating to topological properties and to algebraic geometry, in particular that any polarization of an Artinian monomial ideal defines a simplicial ball.

Waiting Room, Hannah White

Master’s Theses and Projects

The short stories and essays in this hybrid creative collection, Waiting Room, aim to add to critical conversations in both creative nonfiction and fiction about identity in relation to physical places and the body. In this collection, I particularly explore how notions of “home” shape one’s identity: grief, mental/physical illness, displacement from home, and other topics pertaining to the body and physicality.

An Efficient End-To-End Deep Neural Network For Interstitial Lung Disease Recognition And Classification, Masum Shah Junayed, Afsana Ahsan Jeny, Md Baharul Islam, Ikhtiar Ahmed, Afm Shahen Shah

Turkish Journal of Electrical Engineering and Computer Sciences

The automated Interstitial Lung Diseases (ILDs) classification technique is essential for assisting clinicians during the diagnosis process. Detecting and classifying ILDs patterns is a challenging problem. This paper introduces an end-to-end deep convolution neural network (CNN) for classifying ILDs patterns. The proposed model comprises four convolutional layers with different kernel sizes and Rectified Linear Unit (ReLU) activation function, followed by batch normalization and max-pooling with a size equal to the final feature map size well as four dense layers. We used the ADAM optimizer to minimize categorical cross-entropy. A dataset consisting of 21328 image patches of 128 CT scans with …

The "Law To Use The Mark The Delpaís," Act 195-2016: Case Study Of A Puerto Rican Certification Mark With Potential Of Becoming A Geographic Indication For Economic Development, Paola Gabriela Zaragoza Cardenales

Maurer Theses and Dissertations

In 2016, the Puerto Rican Congress codified the “Law for the use of the DelPaís Mark” (the DelPaís Law), creating a composite certification mark called Productos DelPaís de Puerto Rico (the DelPaís Mark) for raw fruits, milk, honey, meats, egg, fish, ornamental plants, spices, vegetables, starches, and value-added products. The Puerto Rican Department of Agriculture intended the DelPaís Mark to function as a certification mark and Geographical Indication (GI) to differentiate local from imported products to promote purchasing of locally produced items and eventually export internationally. A GI is a source identifier identifying that a place makes a particular product …

Predictive Analytics In Child Welfare: Five Principles For Regulating Algorithmic Accountability In A New Wave Of Predictive Models, Michael Blanchard

University of Baltimore Law Review

No abstract provided.

My Own Private Library: A Peek Inside The Personal Library Of A Librarian, Lee Bareford

Georgia Library Quarterly

No abstract provided.

Digital Library Of Georgia (March 2022), Mandy L. Mastrovita

Georgia Library Quarterly

News from the Digital Library of Georgia for the first quarter of 2022.

Book Review: Clothing And Fashion In Southern History, Lindsay Josey

Georgia Library Quarterly

No abstract provided.

Book Review: Hidden Nature: Wild Southern Caves, Linh Uong

Georgia Library Quarterly

No abstract provided.

Immigration In Regard To Economic Labor And Reform, Will Ross, Maryella Mccown, Dylan Stone

Immigration Scholarship: History, Trends and Development in Global Immigration

In the last two presidencies, the United States economy has gone through much development regarding immigration and labor. Many key factors of growth in the economy can be identified pertaining to immigration, such as job fulfillment, innovations, and more productivity. Immigrants arrive in the United States with impressive skills that are needed for many occupations. They also run many of their own businesses and provide food and hospitality services for everyone. A common question that many US citizens wonder is “How do immigrants advantage the United States economy?” By bringing in new skills and ideas that had not been discovered …

65th University Of San Diego School Of Law Commencement Program, 2022, University Of San Diego School Of Law

Commencement Programs

No abstract provided.

Use Of Naltrexone For Alcohol Use Disorder: Closing The Gap In Inpatient Initiation, Nicholas Noverati, Md, Med, Tara Rakiewicz, Md, Kiera Chism, Md, Dina Halegoua-Demarzio, Md, Jillian Zavodnick, Md

Health Equity and Quality Improvement (HEQI) Summit

Project AIM: increase the prescribing of this medication as an inpatient to ideally provide more support to patients with alcohol use disorder