Digital Commons Network^™

Feature Selectivity Of Hippocampal Ca1 Neurons During Memory Encoding, Aden Eagle

Harriet L Wilkes Honors College Theses 2020 - Present

The hippocampus is central to the formation of episodic memories, or memories of personally-experienced events. Episodic memories, in turn, are crucial for navigation along familiar pathways as they can encode information about both external sensory events and internal understandings of position and behavior. The contributions of individual cells in the hippocampus to episodic memory formation and recall during navigation, however, are not well-understood. We recorded the activity of hippocampal CA1 neurons as mice were trained on a particular navigation task which required running a specified distance on a treadmill and then licking on a lick port. Using gradient-boosted decision trees, …

An Analysis Of Mitochondrial Distribution Across Neuron Types In C. Elegans, Reggie Joseph

Harriet L Wilkes Honors College Theses 2020 - Present

Parkinson’s disease is known to have a greater impact on dopaminergic neurons when compared with other neurons. Dopaminergic neurons regulate muscle movement and coordination, and mitochondria supply the energy needed for that function in the form of ATP. Along with ATP production, mitochondria play an essential role in various other cell processes, and it is quite plausible that neurons of different functional and neurotransmitter types have different dependencies on mitochondria. To further investigate this possibility, mitochondrial distribution was analyzed in different neuron types in electron micrographs of Caenorhabditis elegans. Mitochondria were longest (1.65±0.12 μm) in cholinergic interneurons, and shortest in …

Investigating Consumption Behavior In Mice Following Chemogenetic Activation Of Stress-Responsive Neurons, Matthew Pacheco

Harriet L Wilkes Honors College Theses 2020 - Present

Stress is a common factor dealt with in everyday life. Neural circuits activated by stressful stimuli respond in a variety of ways, one being decreased food consumption. Evidence suggests that decreased consumption can be observed in mice following restraint stress. This behavioral response has been associated with the activation of neurotensin (Nts)-expressing neurons projecting from the lateral septum (LS) to the lateral hypothalamus (LH). By using chemogenetic techniques to activate LS neurons that respond to stress, my thesis project seeks to establish to what extent stress-responsive neurons in the LS are involved in the decrease of food consumption.

Defining The Structural And Functional Organization Of Elfn1, Manan Patel

Harriet L Wilkes Honors College Theses 2020 - Present

Interactions involving Extracellular Leucine-Rich Repeat And Fibronectin Type III Domain Containing 1 (ELFN1) and Extracellular Leucine-Rich Repeat And Fibronectin Type III Domain Containing 2 (ELFN2) proteins are important for establishing synaptic properties. Specifically, metabotropic glutamate receptor 6 (mGluR6) is a G Protein-Coupled Receptor (GPCR) that trans-synaptically binds to presynaptic leucine-rich repeat (LRR) ELFN1. ELFN1 has also been reported to anchor mGluR6 across retinal synapses thus highlighting the need to explore the effects of ELFN1 on mGluR signaling and pharmacology, as the interactions on these properties are largely unknown. Another important aspect of research involves establishing the necessity for both ELFN1 …

Do Sponges Niphates Digitalis And N. Erecta Survive A Multi-Year Coral Reef Bleaching Event?, Alexandra Perez

Harriet L Wilkes Honors College Theses 2020 - Present

The 2014-17 El Niño Southern Oscillation (ENSO) created a multi-year thermal anomaly that had a severe global impact on coral reefs; however, it is unknown if all reef organisms were negatively impacted. Previous studies suggest that sponges (phylum Porifera) utilize their regenerative capability to survive stress-inducing conditions; however, it is unknown if they employ this ability to survive multi-year thermal stress. This honors thesis determined if populations of the conspicuous Caribbean sponges, Niphates erecta and Niphates digitalis, were affected by the 2014-17 ENSO event in Florida, Broward County Reefs, and evaluated if sponges utilize their regenerative ability under extreme thermal …

Ethnic Differences In Obsessive-Compulsive Disorder Symptomatology: Comparing Symptom Profiles Of Asian-American, Caucasian-American, And Hispanic-American Groups, Tristan Stinchcomb

Harriet L Wilkes Honors College Theses 2020 - Present

This study investigated whether there exist variations in the presentation of obsessive-compulsive disorder symptomatology across ethnic boundaries and, if so, what these differences are. Padua Inventory and Disgust Emotion Scale scores were collected from Asian-American, Caucasian, and Hispanic individuals. The results showed that the Asian-American and Hispanic groups both had significantly higher mean obsessive-compulsive symptom and trait disgust scores than the Caucasian group. Additionally, Asian-American obsessive-compulsive total scores were significantly higher than Hispanic scores. This study replicates and extends previous findings by comparing the Padua Inventory scores of these three groups with larger samples, and suggests that the overall severity …

A Review Of The Current Literature Regarding The Effectiveness Of Psychedelics In Treatment-Resistant Psychiatric Disorders, Emmy Weisenberg

Harriet L Wilkes Honors College Theses 2020 - Present

In recent years, the numbers of psychiatric cases have nearly doubled. While some treatments options are available, an increase in the prevalence of treatment-resistant mental health disorders represent a need to develop other therapeutics for maladaptive behavioral management. Currently, the serotonergic psychedelic LSD, ketamine, psilocybin, and MDMA in the micro-dosing form are being investigated for their efficacy in the treatment-resistant individuals. Ongoing trials indicate that not only are psychedelics efficacious and safe in the micro-dosing form, but this form of medication may provide both immediate and long-term relief. There is evidence to show that all four aforementioned hallucinogens are capable …

Assessment Of A New Mouse Model For Chronic Fatigue Syndrome: Studies Of The Viral Mimetic Poly I:C On Biochemical Measures Of Brain Inflammation And Serotonin Signaling, Tiffany Zhang

Harriet L Wilkes Honors College Theses 2020 - Present

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, multisystem disease characterized by severe fatigue without medical explanation. Due to the complexity of the disease, treatments only partially alleviate symptoms and currently there is no cure. To develop more effective treatments and better understand its etiology, valid preclinical models need to be developed. Evidence suggests infection and serotonin homeostasis plays a role in the development of ME/CFS. Therefore, I aimed to examine whether a viral mimetic (Poly I:C) triggers long-term fatigue behavior and neuroinflammation in a mouse model. C57 and CD1 male mice were treated with Poly I:C and only CD1 …

Utah Farmers Market Network: Diversity, Equity, And Inclusion Community Of Practice, Jaclyn Pace, Regan Emmons, Kelsey Hall, Celina Wille, Lacee Jimenez, Carrie Durward, Roslynn Mccann

All Current Publications

The Utah Farmers Market Network convened a virtual Diversity, Equity, and Inclusion (DEI) Community of Practice (CoP) to explore how markets could be more welcoming and inclusive to historically excluded populations. Between May and November of 2021, members of seven Utah farmers markets convened at least twice monthly to explore basic DEI concepts and create personalized DEI strategic plans for their markets. This document reviews impacts on participants and the personal, market, community, and organizational goals created.

Utah Farmers Market Snap Toolkit, Regan Emmons, Bridget Stuchly, Gina Cornia

All Current Publications

Utah State University Extension provides research-based programs and resources with the goal of improving the lives of individuals, families and communities throughout Utah. USU Extension manages Create Better Health, Utah’s Supplemental Nutrition Assistance Education Program (known as SNAP-Ed), and provides nutrition education and obesity prevention services to SNAP recipients and other eligible low-income individuals. Create Better Health (SNAP-Ed) offers a variety of classes to expand participants’ knowledge of nutrition, budgeting, cooking, food safety, and physical activity. This toolkit outlines how farmers markets can implement a SNAP program and help combat food insecurity in their communities.

Don't Forget The "G" In Esg: The Sec And Corporate Governance Disclosure, Jennifer O'Hare

Faculty Publications

For years, many shareholders—both institutional and individual investors—have pressured the Securities and Exchange Commission (“SEC”) to require public companies to disclose more information about the environmental, social, and governance (“ESG”) risks facing the company. However, the SEC has generally refused calls to require public corporations to disclose, for example, how they are addressing climate change or workforce diversity challenges. With a new president in the White House and a new administration at the SEC, the SEC will soon propose new ESG disclosure rules, requiring more information about the “E” and the “S” in ESG. But the SEC has forgotten the …

5.2.22, Amber Brost

ASWC Agendas

No abstract provided.

Introduction: Covid, Contract, And Crises, Jonathan C. Lipson, Rachel Rebouché

Law and Contemporary Problems

No abstract provided.

A Comment On Hillman, Health Crises, David A. Hoffman

Law and Contemporary Problems

No abstract provided.

A Comment On Colla And Gulati, Cheeky Contracting, Tess Wilkinson-Ryan

Law and Contemporary Problems

No abstract provided.

A Comment On Foohey Et Al., Steering Loan Modifications Post-Pandemic, Susan Block-Lieb

Law and Contemporary Problems

No abstract provided.

The Transactional Dynamic Of Market Fragility, Matthew Jennejohn

Law and Contemporary Problems

No abstract provided.

Therapeutic Efficacy Of Zinc In The Treatment Of Covid-19 Patients: A Systematic Review, Olivia Schimmel, Varna Taranikanti

Posters

INTRODUCTION
Novel therapeutic interventions are of utmost importance to alleviate the clinical symptoms caused by inflammation in COVID-19 patients. The beneficial role of zinc has been suggested due to its ability to mitigate the effects of the inflammatory cascade. Hence it has been hypothesized that patients with zinc deficiency may benefit symptomatically from treatment with zinc. The primary goal of this systematic review of randomized controlled trials conducted between February and March 2021 is to determine the efficacy of zinc as a treatment for COVID-19 infection.

The Case For Oer As The Advancement Of Knowledge/Creative Expression, Amber Dierking, Matt Ruen, Steven Schlicker

Library Reports and Communication

The nature of scholarly and creative activity, at Grand Valley State University and across the higher education sector, is rapidly evolving. Amidst this ongoing transformation, the characteristics of OER – free access plus permission for adaptation – empower Grand Valley’s teacher-scholars to share their expertise with a global audience and simultaneously remove barriers to education for Lakers.

This memo, submitted for consideration by the University Academic Senate at GVSU, argues that the creation of OER can demonstrate several of the forms of scholarly activity described by Boyer (1990) as well as the criteria established for the Advancement of Knowledge or …

Saying Yes To (Mostly) Everything - Journey To Commencement, Lydia Lagarde

Journey to Commencement

Richard Springer opened up to a lifetime of experiences at Ole Miss.

Sparking Confidence Through Competition - Journey To Commencement, Nell Floyd

Journey to Commencement

Ole Miss prepares Lauren Taylor to embark on graphic design career.

“Onq”: Contextual Information Design, Sally Boniecki

Theses

There is a countless amount of entertainment media available to a single viewer, and the internet makes that media easily accessible. However, keeping up with the rules, objectives, backstory, or culture of each one is difficult, and confusion hinders enjoyment. My thesis, “OnQ” dismantles the barrier of information in broadcast sports, viewership of which has been declining for 10-20 years. By exploring the flow of information, user interaction, user multitasking, and graphic design via on-demand explanations and statistics on top of live video, “OnQ” takes existing multitasking behavior and integrates it onto the same screen as the broadcast. Instead of …

Community Cat Shelter - A System That Brings The Community Together To Raise Community Cats, Zhishuo Sun

Theses

Due to the frequent abandonment of domestic cats and their proliferation in the wild, more and more stray cats, or feral cats, have been born in the city. These cats have a high mortality rate, kill birds, make noise, and have an impact on the human habitat. This study explores the pain points of harmonious coexistence between humans and stray cats and proposes a design intervention for some of these problems. The goal is for each community to address the problem of stray cats in that community from within, including issues such as securing the survival of stray cats and …

Elimination Of Postoperative Narcotics In Infant Robotic Pyeloplasty Using Caudal Anesthesia And A Non-Narcotic Pain Pathway, Kwesi Asantey, Kristen Meier, Zachary Rollins, Andrew B. Banooni, Zachary J. Liss

Posters

INTRODUCTION
Research suggests that narcotic pain medications are dramatically overprescribed. We hypothesize that narcotics are unnecessary in the majority of infants for postoperative pain control. In this series, we report our experience combining caudal blocks with a non-narcotic postoperative pathway as a means of completely eliminating postoperative narcotics following infant robotic pyeloplasty.

Helium-Like X-Ray Line Complexes Show That The Hottest Plasma On The Zeta Supergiant Puppis Is In Its Wind, David H. Cohen, Ariel M. Overdorff, Maurice A. Leutenegger, Marc Gagné, Veronique Petit, Alexandre David-Uraz

Earth & Space Sciences Faculty Publications

We present an analysis of Chandra grating spectra of key helium-like line complexes to put constraints on the location with respect to the photosphere of the hottest (T greater than or similar to 6 x 10(6) K) plasma in the wind of the O supergiant zeta Pup and to explore changes in the 18 yr between two sets of observations of this star. We fit two models - one empirical and one wind-shock-based - to the S XV, Si XIII, and Mg XI line complexes and show that an origin in the wind flow, above r approximate to 1.5 R*, …

Cardiorespiratory, Hemodynamic, And Perceived Exertion Responses To Seated Chair Exercise, Ryan Khemraj, Cristian Solano, Neesirg Patel, Roger Sacks

Posters

INTRODUCTION
The increasing prevalence of cardiovascular disease (CVD) and its sequelae in the United States population has led to escalating health care expenditures. To favorably modify cardiovascular outcomes, exercise physiologists have developed varied exercise programs that are associated with mortality reduction, symptom relief, improved exercise tolerance, favorable risk factor modification and improved psychosocial well-being. For patients with significant disability and deconditioning, chair-based exercise may provide an alternative method of achieving the relative cardioprotective benefits of traditional exercise.

Deloitte, Foundation Endow $1.5m Um Accountancy Chair, Jonathan Scott

University of Mississippi News

Gift helps attract, retain top faculty to renowned program

The Echo: May 2, 2022, Taylor University

2021-2022 (Volume 109)

TU tours Civil Rights monuments — Student Senate restructures for next school year — Taylor receives $3 million gift for film building — Choros survey prompts student discussion — Taylor reviews 25-Live — A new community buzzes on campus — Advancement team raises money for Taylor — Finding time for Sabbath rest — Challenge your community — The Apartments are dorms too — Theatre finishes production season with ‘Annie’ — Boren Art Gallery opens inside Helena Memorial Hall — Senior Fine Arts Feature — Brewing and community — Finding moms in Taylor’s classrooms — Modern Solutions Required — Jung carries …

Uk Passes Its Own Animal Sentience Act After Leaving The Eu, Andrew N. Rowan

WellBeing News

When the UK (United Kingdom) voted to leave the European Union (EU), one of the

consequences would be the loss of legislation on various issues covered in

existing EU laws. The UK government had to pass new laws covering the many

items in EU legislation that would no longer apply to the UK, including the

statement in the EU governing treaty that animals were sentient. The

Conservative Government had promised to address the complicated range of

legislative gaps, including the declaration that animals are sentient beings, that

would be precipitated by the UK’s departure from the EU via new omnibus …

Dog Behavior And Aggression, Andrew N. Rowan

WellBeing News

An extensive study of the genetics of dog behavior (including individual dog personality) and appearance (physical traits) has just appeared in the major academic research publication, Science. The research team reviewed the behavior and genes of 2,000 dogs who had had their entire genomes sequenced. An additional 16,000 dogs, including mixes and pure breeds (128 represented), were also reviewed for behavior traits. The study reported that less than a quarter of the differences in dog personality could be explained by genetics. In contrast, at least 80% of the physical traits were closely tied to the dog’s DNA. These findings are …