Digital Commons Network^™

Monitoring Adherence To Hcv Screening Among The Baby Boomer Population, Sarah Miller Bsn, Rn, Autumn Spight Bsn, Rn, Mahogany Freeman Bsn, Rn, Sharon Little Dnp, Aprn, Fnp-Bc, Laura Reed Dnp, Fnp

Doctor of Nursing Practice Projects

Purpose/Background Chronic hepatitis C is currently the most common cause of liver disease in the United States and is associated with various complications that increase mortality and morbidity, yet many people go unidentified and thus untreated. The CDC created guidelines in 2012 for hepatitis C screening and testing among the baby boomer population due to their high rates of HCV infection and HCV-related mortality. Our project aimed to assess the adherence of hepatitis C screening, based on these CDC guidelines, of individuals within the baby boomer population (1945-1965) in the primary care setting through retrospective chart review.

Methods A 6-month …

Esmolol Compared To Fentanyl On Hemodynamic Effects: A Scoping Review, Anna Mccleskey Bsn, Rn, Srna, Landon Mcdonald Msn, Rn, Cnl, Tim Moore Bsn, Rn, Srna, Jamie Pitcock Bsn, Rn, Srna, Dwayne Accardo Dnp, Crna, Aprn

Doctor of Nursing Practice Projects

Purpose The purpose of this DNP project is to compare the efficacy of esmolol to fentanyl in attenuation the hemodynamic response associated with direct laryngoscopy.

Specific Aims Compare the effects of esmolol to fentanyl on patient heart rate during laryngoscopy. Compare the effects of esmolol to fentanyl on patient mean arterial pressure during laryngoscopy.

Transferring Patients To A Higher Level Of Care, Chiquita Rockiemore Rn, Msn, Olubunmi Osinloye Bsn, Rn, Angela Uta Bsn, Rn, Tracy Mcclinton Dnp, Ag-Acnp-Bc

Doctor of Nursing Practice Projects

The purpose of this study is to determine whether the transfer of critically ill patients, who require a higher level of care, to another facility impacts morbidity and mortality within 24-72 hours post transfer

Csf Flow Cytometry In Patients With Leukemia And Lymphoma, Patricia Rusli, James Huang

Posters

INTRODUCTION
The use of flow cytometric testing in analyzing bodily fluid for hematologic neoplasms is not novel. Flow cytometric immunophenotyping of cerebrospinal fluid (CSF) has previously been demonstrated to have high sensitivity and specificity for the detection of lymphoma and leukemia. They are able to determine definitive diagnostic information from even very low cellularity samples. In this study, we reviewed the experience of our clinical flow cytometry laboratory in evaluating CSF specimens in order to find the disease distribution of positive CSF samples.

Identification Of Aggressive Variants Of Mantle Cell Lymphoma Based On Flow Cytometry, Alan Nguyen, Alia Gupta, Marc Smith, James Huang

Posters

INTRODUCTION
Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphoma characterized by a (1,14) translocation resulting in overexpression of cyclin D1.1 MCL variants and a heterogenous disease presentation make this a challenging diagnosis with a highly variable outcome. Pleomorphic and blastic variants have an aggressive clinical course and shorter survival than the classical type.2 The pleomorphic variant shows a marked variation in nuclear size, shape, and mitotic index.3 The blastic variant appears small and immature with fine chromatin mimicking acute leukemia.3 The aim of our study is to explore if flow cytometry analysis can help with the …

Reporting Of Concussion Symptoms In High School Aged Athletes, Aimee Hite, Patrick Karabon, Neil Alpiner

Posters

INTRODUCTION
Each year, one to two million concussions occur in the youth populations and constitute 8.9% of all high school athletic injuries. However, current literature lacks studies that focus on concussion symptoms. This study sought to ascertain the prevalence of reporting concussion symptoms and continuing to play while experiencing symptoms in high school aged athletes.

Post-Concussive Visual Symptoms In Teens Undergoing Rehabilitation, Daniel Ludema, Neil Alpiner

Posters

INTRODUCTION
Visual symptoms are commonly reported in those who have experienced mild TBI. However, there has not been much research on other types of visual disturbances commonly seen in the post-concussive period. The goal of this study was to identify novel visual symptoms seen in post-concussive teens.

Imposter Syndrome And Depressive Symptoms In Medical Students, Christopher Gilbert, Varsha Karamchandani

Posters

INTRODUCTION
Imposter syndrome (IS), characterized by chronic feelings of self-doubt as well as fear of being discovered as an intellectual fraud, has been reported to have a high prevalence among medical student populations. Many forms of psychological distress, such as depressive symptoms, have also been found to have a high prevalence among medical student populations. Combined, these can lead to poor scholastic performance and poor mental health. The object of this research is to gather data by survey about the prevalence of IS within the medical student community and explore its potential relation to depressive symptoms.

Prospective Qualitative Analysis Of Minimally Invasive Repair Of Pectus Excavatum, Timothy Elton, Diane Studzinski, Robert S. Morden, Pavan Brahmamdam

Posters

INTRODUCTION
Pectus Excavatum is the most common chest wall deformity and is frequently corrected with the Nuss procedure. Although this procedure has existed for several decades, new strategies are being adapted to reduce complications and improve efficiency. The aim of this study is to perform a qualitative review of the patient experience after minimally invasive repair of Pectus Excavatum.

Blunt Trauma And Diaphragm Injury In Children: An Analysis Of The National Trauma Data Bank, Sammie Lai, Patrick Karabon, Patrick Modren, Begum Akay, Anthony Stallion, Pavan Brahmamdam

Posters

INTRODUCTION
Trauma is the leading cause of mortality and morbidity in children. Traumatic diaphragm rupture (TDR) is a rare but serious injury that can be difficult to identify. The current literature includes individual case reports and single center case series only, which limits our ability to generalize those findings. The purpose of this study is to use the National Trauma Data Bank (NTDB) in order to examine the clinical outcomes of blunt TDR in the pediatric population.

Let Them Play: A Prospective Study Of Postoperative Activity Restrictions In Children, Rachel Harvey, Begum Akay, Diane Studzinski, Nathan Novotny, Anthony Stallion, Pavan Brahmamdam

Posters

INTRODUCTION
We aim to compare time to resume full activity, postoperative outcomes, and describe family preferences of self-directed activity restrictions (SDAR) and physician-directed activity restrictions (PDAR) following routine pediatric surgeries.

Perioperative Antibiotic Use In Neonatal Surgery, Lior Kopel, Patrick Karabon, Nathan Novotny, Begum Akay, Pavan Brahmamdam

Posters

INTRODUCTION
The ideal duration of perioperative antibiotic prophylaxis to prevent surgical site infection (SSI) in neonates is undetermined. The aim of this study is to evaluate the association between the duration of perioperative antibiotics and SSIs in the neonatal surgical population.

Spontaneous Pneumomediastinum In Children Is Not Associated With Esophageal Perforation, Kevin Roby, Catherine Barkach, Diane Studzinski, Nathan Novotny, Begum Akay, Pavan Brahmamdam

Posters

INTRODUCTION
We hypothesize that esophageal perforation is not a common etiology for spontaneous pneumomediastinum (SPM), and that SPM is a self-limited disease not requiring routine admission.

Hearing Durability And Trajectory After Radiosurgery For Vestibular Schwannoma, Christian G. Fritz, Dennis I. Bojrab Ii, Nathan C. Tu, Christopher A. Schutt, Dennis I. Bojrab, Seilesh C. Babu

Posters

INTRODUCTION
Vestibular schwannomas (VS) are benign skull base tumors arising from the eighth cranial nerve. Stereotactic radiosurgery (SRS) is emerging as treatment for smaller sized tumors with the intent being to prevent further tumor growth, thus avoiding mass-effect symptoms. Hearing outcomes are commonly presented as preservation of class A/B hearing (defined as Pure Tone Average (PTA) ≤50 dB with Word Recognition Score (WRS) ≥50 dB). Long-term follow-up data on hearing outcomes and hearing trajectory trends are limited.

Development Of A Deep Neural Network For Synthesis Of Non-Contrast Cranial T1-Weighted Magnetic Resonance Imaging, Agueda M. Taylor, Evan Porter, Thomas Guerrero

Posters

INTRODUCTION
Although 122 out of 1000 people in the US have MRI’s done each year, there are over 4 million with contraindications that subsequently forgo the diagnostic benefits. Studies in recent years have implemented artificial intelligence (AI) algorithms such as deep neural networks (DNN) for production of synthetic medical imaging. The goals of this project are to develop a DNN, specifically a Generative Adversarial Network (GAN) that will predict synthetic Cranial T1 Weighted MRI from non-contrast CT, and to evaluate the model quality.

Functional Lung Segmentation From Computed Tomography Images Using Deep Learning, Duyen M. Quach, Evan Porter, Thomas M. Guerrero

Posters

INTRODUCTION
Functional avoidance treatment planning allows radiation oncologists to intentionally minimize radiation dose to higher-functioning lung areas while favoring radiation dose towards lower-functioning regions. This treatment planning method has been shown to reduce pulmonary toxicity for patients receiving radiation therapy. Functional lung information, traditionally ventilation or perfusion SPECT scans, is required to plan for functional avoidance.

Evaluating The Impact Of Software Distortion Correction On Target Doses In Cranial Stereotactic Radiosurgery, Sharjil Shamim, Zachary Seymour

Posters

INTRODUCTION
Brainlab’s Elements suite proposed a novel MR distortion correction method based on CT imaging. This involves registration of sub-volumes from MR imaging to generate single continuous deformation field maps, creating a corrected MR image set. No literature currently exists studying the impact of software correction on target dose for cranial stereotactic radiosurgery. In this study, we aim to evaluate the impact of Brainlab distortion correction on radiation target dose compared to original treatment plans without distortion correction.

The Prognostic Significance Of Glucose-6-Phosphate Dehydrogenase As A Biomarker In Head And Neck Squamous Cell Carcinomas Treated With Conventional Chemoradiation, Kenneth H. Barker, Barbara L. Pruetz, Jessica D. Arden, Thomas J. Quinn, George D. Wilson

Posters

INTRODUCTION
The prognosis of patients with head and neck squamous cell carcinoma (HNSCC) treated with chemoradiation can be predicted using p16 as a surrogate biomarker of Human Papilloma Virus (HPV) status, but a subset of patients continues to do poorly despite a positive or negative p16 status. This project attempted to identify another biomarker, glucose-6-phosphate dehydrogenase (G6PD) as a marker for prognosis in HNSCC patients. Radiation induces oxidative damage to destroy tumor cells, and G6PD is a key enzyme involved in protecting cells from oxidative damage. The goal of this project was to identify a prognostic biomarker that would aid …

Irreversible Electroporation For Recurrent Pelvic Metastases: Case Series And Literature Review, Duncan A. Stevens, Jeffrey H. Savin, Brett J. Friedman, Michael A. Savin

Posters

INTRODUCTION
Irreversible electroporation (IRE) is a nonthermal ablative technique that has potential safety advantages over thermal ablation in the treatment of tumors near critical structures. It creates an electrical field which forms permanent nanopores in the membranes of cells and triggers apoptosis. This case series reviews three patients with pelvic metastases from colorectal cancer treated with IRE.

Factors Influencing Reintubation In Self Extubated Pediatric Intensive Care Unit Patients, Ahmed Naseem, Ameer Al-Hadidi, Morta Lapkus, Patrick Karabon, Begum Akay, Paras Khandar

Posters

NTRODUCTION
Intubated pediatric patients that self-extubate may be particularly susceptible to reintubation. Identifying factors that increase risk of reintubation allows for better monitoring and response in cases of self-extubation and can potentially identify patients needing reintubation.

Association Of Gut Metabolomic Biomarkers With Sleeve Gastrectomy Weight-Loss Outcomes, Pamela Spicer, Wendy Miller, Kathryn Ziegler, Stewart Graham

Posters

INTRODUCTION
Obesity is a prevalent health challenge with high morbidity and many associated chronic diseases. Sleeve gastrectomy is currently the predominant intervention for obesity. However, weight loss results are variable. The mechanisms and factors influencing this variability are not well understood. We evaluated the correlation of metabolomic biomarkers with weight-loss.

Custom Ampliseq Targeted Sequencing Panel For Orphan Pediatric Retinal Diseases: Norrie Disease, Fevr, And Retinoschisis, Michael Sun, Wendy Dailey, Amanda Petrilli Cicerone, Jennifer Felisky, Kaylee Moyer, Naomi Haque, Alvaro Guzman, Kendra Mellert, Kimberly Drenser, Kenneth P. Mitton

Posters

INTRODUCTION
DNA-sequencing is not readily available in countries with little research resources or where health insurance does not cover the costs. This is especially true for very rare (orphan) inheritable retinal diseases. We wanted to develop a rapid targeted-sequencing protocol for eight genes involved in Familial Exudative Vitreo-Retinopathy (FEVR), Norrie Disease, and Retinoschisis, at greatly reduced cost.

Intraoperative Map, Vasopressors, And Opioids In Tf-Tavr Patients Undergoing Conscious Sedation Vs General Anesthesia, Brett J Friedman, Patrick Karabon, Wei C Lau

Posters

INTRODUCTION
Aortic stenosis is a progressive narrowing of the aortic valve that can cause serious cardiovascular harm such as syncope, heart failure, and death if left untreated. Transfemoral-transcatheter aortic valve replacement (TF-TAVR) emerged in the last 10 years as an alternative for previously inoperable, high-risk patients. Studies suggest that monitored anesthesia for TF-TAVR using minimalist conscious sedation results in better outcomes (e.g., shorter length of stay, lower 30-day mortality) when compared to general anesthesia. However, there is a gap in knowledge of why conscious sedation is more successful. Recent studies have demonstrated the association of intraoperative mean arterial pressure (MAP) …

Outcomes For Patients With Congestive Heart Failure And Chronic Kidney Disease Receiving Fluid Resuscitation For Severe Sepsis Or Septic Shock, Melany Wiczorek, Ronny Otero, Steven Knight, Kaitlin Ziadeh, James Blumline, Zachary Rollins

Posters

INTRODUCTION
Sepsis core measures are an integral part of sepsis treatment. Current fluid administration guidelines consist of administering at least 30cc/kg of intravenous fluids (IVF) per ideal body weight (IBW) within the first three hours of sepsis diagnosis regardless of pre-existing comorbidities at risk for fluid overload. This study aims to evaluate the outcomes of patients with a history of congestive heart failure (CHF) and/or chronic kidney disease (CKD) who receive fluid resuscitation for the management of severe sepsis or septic shock.

Journal Club In The Pre-Clinical Years During Medical School, Kristin Cuadra, Steven Joseph

Posters

INTRODUCTION
Traditionally, journal clubs have been conducted within graduate medical programs to help integrate evidence-based learning. This study will be focused on beginning to integrate journal club into the pre-clinical years while implementing successful techniques used in past journal clubs. Our hypothesis is that, with a structured review instrument in place to help students analyze clinical articles, students will be able to benefit from monthly journal clubs and fully grasp concepts taught in these pre-clinical years. Overall, the results will contribute significantly in determining the efficacy of journal club and whether or not it can be a valuable tool in …

Late Outcomes For Patients With Acute Chest Pain And Positive Fractional Flow Reserve By Computed Tomography, Zach Rollins, Jason Schott, Robert Safian

Posters

INTRODUCTION
Testing with fractional flow reserve derived from computed tomography (FFRCT) can be used to stratify otherwise indeterminate grade stenoses on cardiac computed tomography angiography (CCTA). Long-term clinical outcomes using FFRCT have been reported in stable heart disease but not for acute chest pain (ACP). This study analyzes clinical outcomes in patients with ACP who underwent FFRCT, including the risk of mortality, myocardial infarction (MI), invasive coronary angiography (ICA), and revascularization.

Does Aspirin Reduce Risk For Future Cardiovascular Events In Women With Diabetes?, Olivia Hillier, Amna Zeb, Pamela Marcovitz

Posters

INTRODUCTION
The use of low dose aspirin (LDA) in primary prevention of cardiovascular events (CVE) is no longer recommended due to lack of benefit in prevention of primary outcome and increased bleeding risks. It’s postulated that LDA could still be of benefit in those with very high vascular risk including diabetes mellitus (DM) as it confers a higher risk for future CVE in women as compared to men. We conducted a meta-analysis to determine if use of low dose ASA is beneficial to lower CVE in women with multiple risk factors.

Impact Of Polycystic Ovary Syndrome On Cardiovascular Disease In Obese Female Youth, Collin R. Walentine, Michael R. Brennan, Kristen J. Nadeau, Melanie Cree-Green

Posters

INTRODUCTION
17% of youth in the United States are obese and the incidence is rising. Among obese adolescents, girls with polycystic ovary syndrome (PCOS) represent a vulnerable and understudied group. PCOS is strongly associated with dyslipidemia and cardiovascular disease (CVD) in adulthood, but studies of CVD in youth are limited. We hypothesized that obese youth with PCOS would show evidence of vascular dysfunction relative to girls with obesity without PCOS.

Patient Perceptions Of Their Health Care Teams And Preferences For Making Decisions Regarding Medical Care, Veronica F. Williams, Nelia Afonso

Posters

INTRODUCTION
Beaumont Hospital values patient and family-centered care, but a clear understanding of how patients perceive their health care teams and prefer to make decisions regarding their medical treatment have not been well-described. It is necessary to understand patients’ preferences regarding various factors that impact their medical care in order to foster an effective health care environment. The primary goal of this study is to determine how patients’ care teams impact the ways in which they make decisions regarding their medical treatment. A secondary goal is to determine the individuals, both inside and outside of the health care setting, that …

Effectiveness Of Prenatal Screening Tests On Predicting Cardiac Anomalies, Stephanie Y. Wong, Zeynep Alpay Savasan

Posters

INTRODUCTION
Congenital heart disease (CHD) is the leading cause of birth defect-associated infant death. With 1 in 111 newborns born with CHD and an elevated infant mortality rate of 30-50%, early detection is imperative. Current prenatal screening mainly focuses on detecting chromosomal anomalies. However, the accuracy of these exams on detecting fetal cardiac abnormalities is not well researched. The primary goal of this study is to compare three prenatal screening tests’ potential, i.e anatomy ultrasound, nuchal translucency (NT), and cell-free DNA (cfDNA), in identifying risk for fetal cardiac anomalies.