Digital Commons Network^™

Feeding And Swallowing Disorders In 100 Children With 22q11.2 Syndrome, Jana Ghulmiyyah

Research Days

Watch recording of live event

Background: 22q11.2 deletion syndrome (22q11DS) is the most common microdeletion syndrome. The syndrome includes a wide range of variable features including congenital heart disease, palatal abnormalities, immune deficiency and learning difficulties. Otolaryngologic manifestations include hearing loss, characteristic facial features and laryngotracheal abnormalities. A few studies have reported dysphagia as a common feature of this syndrome however little is known about the specific feeding and swallowing difficulties that occur in children with 22q11DS.

Objectives/Goal: The aim of the study is to identify the frequency of feeding and swallowing disorders in a large cohort of pediatric patients …

Evaluation Of A Modified Pre-Medication Algorithm For Non-Emergent Intubation In A Neonatal Intensive Care Unit, Lilah Melzer

Research Days

Watch recording of live event

Background: The use of pre-medication for elective non-emergent intubation in neonates and infants has been suggested to minimize physiologic instability, decrease oral/pharyngeal trauma and decrease time and attempts to successful intubation. A pre-medication algorithm including the use of Fentanyl + Atropine was modified to include a higher dose of fentanyl with addition of muscle relaxant and benzodiazepine in a level IV neonatal intensive care unit.

Objective: The objective of this study was to compare first attempt success of intubation pre- vs post-modification of the pre-medication algorithm.

Methods: This is a single site retrospective chart review. …

Inpatient Outcomes For Children Receiving Empiric Methicillin-Resistant Staphylococcus Aureus Coverage For Complicated Pneumonia, Sophia Hackman

Research Days

Watch recording of live event

Background: Pediatric community acquired pneumonia is responsible for an estimated 124,000 hospitalizations annually in the United States, with up to 40% of hospitalized children subsequently developing a complicated pneumonia (i.e., effusion/empyema). Children with complicated pneumonia commonly require increased numbers of procedures, have exposure to broad-spectrum antibiotics, and have prolonged hospitalizations. While the prevalence of pneumonia has overall declined with childhood vaccination, the number of children with complicated pneumonia has remained stable. Current guidelines do not adequately address antibiotic management of pediatric complicated pneumonia specifically when to utilize methicillin-resistant Staphylococcus aureus (MRSA) coverage, likely contributing to …

Improving Antibiotic Durations For Skin And Soft Tissue Infections In Pediatric Urgent Care Clinics, Megan Hamner

Research Days

Watch recording of live event

Problem Statement/Question: Although national guidelines recommend 5-7 days of oral antibiotics for most skin and soft tissue infections (SSTIs), in 2019, CMH urgent care clinics (UCCs) prescribed > 7-day courses for 42% of patients diagnosed with SSTIs. Prolonged antibiotic courses result in increased patient burden, cost and adverse events which could be prevented by prescribing shorter courses.

Background/Project Intent (Aim Statement): To increase the percentage of patients receiving 5- 7 days of oral antibiotics for SSTIs from 58% to 75% by December 31st, 2021, in CMH UCCs.

Methods (include PDSA cycles): We formed a multidisciplinary team …

A Novel Approach To Triosephosphate Isomerase Deficiency, Kyra Mccarty

Research Days

Background: Triosephosphate isomerase deficiency (TPID) is a glycolytic pathway enzymopathy causing hemolytic anemia and neurologic dysfunction. TPID is caused by mutations in the TPI1 gene. These patients experience severe hemolytic anemia in infancy followed by progressive neurodegeneration. Diagnosis of TPID is made by measuring decreased TPI enzyme activity elevated dihydroxyacetone phosphate (DHAP) levels in the blood. The diagnosis is confirmed by molecular genetic testing. Neurological involvement typically manifests between 6 and 24 months of age, causing progressive motor dysfunction. Chronic axonal neuropathy is often present on nerve biopsy, and peripheral neuropathy is evident on electrophysiologic studies. Splenectomy and blood transfusions …

Supraclavicular Neck Mass In A 14 Month Old Boy, Jana Ghulmiyyah

Research Days

Background: Lipoblastoma is a rare benign tumor arising from embryonic fat cells in children younger than 3 years of age. They rarely present in the neck and usually do not have spindle cell appearance. We therefore present a case of neck lipoblastoma with review of the literature.

Case Description: We present the case of a 14-month-old male who presented with 1 month history of a right supraclavicular neck mass that was enlarging gradually. On physical exam, it was non tender, mobile with no overlying skin changes. Patient did not have any respiratory distress. A fine needle aspirate (FNA) showed spindle …

Diagnostic Features And Clinical Outcomes Of Children With Tubulointerstitial Nephritis And Uveitis Syndrome (Tinu), Christian Oliveros

Research Days

Background: Tubulointerstitial nephritis and uveitis (TINU) syndrome is an inflammatory disease that affects the kidneys and eyes. TINU is rare, but likely under-recognized due to variable clinical presentation, nonspecific symptoms, and lack of universally accepted diagnostic criteria. The optimal treatment approach in children with TINU remains unknown.

Objectives/Goal: The purpose of this case series is to contribute further knowledge to this rare disease by describing disease features and treatment response of patients with TINU treated at a single center.

Methods/Design: A retrospective chart review was performed of children diagnosed with TINU at a single tertiary care children’s hospital since January …

Primary Venous Thromboprophylaxis In Pediatric Oncology Patients, Kyra Mccarty

Research Days

Background: The Virchow’s Triad principles of venous stasis, endothelial damage, and hypercoagulability are all features of malignancy and contribute to the increased risk venous thromboembolism (VTE) seen in oncology patients. Additionally, certain chemotherapy treatments, presence of a central venous catheter and immobility are also intrinsically associated with malignancy diagnoses and exacerbate this risk. However, much debate exists over the use of thromboprophylaxis in the pediatric population, primarily due to lack of evidence regarding safety and efficacy, primarily the risk of major bleeding. Multiple retrospective studies have attempted to identify the primary risk factors for VTE in this pediatric oncology patient …

Development Of Medical Alert Cards Using Structured Data To Assist In The Management Of Children With Anorectal Malformation, Cloaca, And Cloacal Exstrophy, Ninad Prasade

Research Days

Introduction: Anorectal malformations (ARM), including cloaca and cloacal exstrophy, are a rare collection of congenital disorders of the distal hindgut resulting in lifelong anatomic and functional impairments. Children with ARM may often have other congenital anomalies in the VACTERL association (vertebral, anorectal, cardiac, tracheoesophageal fistula, renal, limb), leading to anatomic variations and prior surgeries that require consideration in diagnosis and management. Patients with these conditions may have multiple presentations to the healthcare system. Understanding emergencies specific to these conditions can enable patients' families and providers to quickly recognize important anatomic variations and initiate care management.

Aim: Our study aimed to …

Identify Factors Associated With Excessive Corneal Haze Noted To Have Increased In Frequency Over The Last 6 Months Post Corneal Cross-Linking Procedure, Sonal Dangda

Research Days

Problem Statement/Question: Over the past 6 months, increased post-operative corneal haze and decreased vision was noted in patients following corneal crosslinking for keratoconus.

Background/Project Intent (Aim Statement): Identify factors that may contribute to increased postprocedure haze and analyze these factors for the total cohort of crosslinking patients since 2017. The goal of this study is to ensure that the increased haze is due to unique patient factors and not an external cause.

Methods (include PDSA cycles): Patients who underwent corneal cross-linking between January 2017 – December 2021 were identified. Retrospective data was collected at baseline visit, at one-month postcrosslinking and …

Outcomes Of A Quality Improvement Project: Implementing Trauma Informed Care In A Neonatal Intensive Care Unit, Jennie Godwin

Research Days

Problem Statement/Question: Will providing Trauma Informed Care (TIC) education to physicians in a large Level IV NICU increase their uptake and implementation of TIC practices?

Background/Project Intent (Aim Statement): The experience of being hospitalized in a Neonatal Intensive Care Unit (NICU) is recognized as a traumatic stressor to both the infants and their families. Physicians working in the NICU experience indirect traumatization and are at risk for burnout. Trauma Informed Care (TIC) can increase effectiveness of healthcare delivery, ensure that staff, policies and procedures do not cause unintentional harm, promote staff resilience, and improve the overall quality of the patient …

Initiating Coordination Of Care For Children In State Custody Or Shelter Care, Angela Doswell

Research Days

Problem Statement/Question: Children in the foster care system experience barriers to continuity of care, both in the primary and subspecialty outpatient settings.

Background/Project Intent (Aim Statement): To decrease average percentage of scheduled but missed specialty appointments whose initial referrals were placed in the Foundations Foster Care Clinic (FCC) from 40% to 20% over a 10- month period from March-December 2020.

Methods (include PDSA cycles): Referrals to specialty clinics were placed during an initial or follow-up visit in the Foundations Foster Care Clinic (FCC). One PDSA cycle was performed and involved notification of the patient’s case worker when a referral was …

Improving Transition To Adult Care Discussion In A Diabetes Clinic, Erica Wee, Erica Zarse, Lindsay Baldridge

Research Days

Problem Statement: Diabetes mellitus is a chronic condition requiring complex care. Adolescents with diabetes face challenges when transitioning to an adult care setting which can lead to suboptimal glycemic control and emergence of complications. It is important for a pediatric diabetes clinic to provide support and prepare adolescents for success when they transfer to adult care.

Aim Statement: In our diabetes clinic, patients are eligible for transition assessment if they are over age 17 years without a documented discussion in the past 1 year. A review of clinic data between October 2021 and November 2021 revealed that an average of …

Nasal Chondromesenchymal Hamartoma: A Case Report And Review Of The Literature, Jana Ghulmiyyah

Research Days

Background: Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor of the sinonasal cavity. It commonly presents in infancy, however there are reported cases of adult tumors. As of August 2021, there have been 56 reported cases in the literature. This is the first description of a solely endoscopically resected NCMH in a neonate in addition to a review of the literature.

Case Presentation: A 5-day old male patient born at term presented to our institution for stridor and cyanosis since birth. The patient was reported to have desaturations while feeding at the outside hospital. On bedside examination, the patient …

Diagnosis, Management, And Treatment Of Lymphadenitis And Deep Neck Space Infections At A Children’S Hospital, Aaron Shaw

Research Days

Background: Although cervical lymphadenitis and deep neck space abscesses (DNSA) are relatively common pediatric diagnoses, no standardized approach exists for management of these infections.

Objectives/Goal: To assess variability in diagnosis and treatment of cervical lymphadenitis and DNSA in a children’s hospital.

Methods/Design: Charts were obtained using ICD9/10 codes for diagnoses of retropharyngeal and parapharyngeal abscess, and lymphadenitis between 1/1/10-12/31/20. 1,237 charts were identified. Patients with a retropharyngeal and/or parapharyngeal abscess were defined as DNSA. Charts were excluded if the diagnosis was not a bacterial infection (e.g. Kawasaki disease), if the lymphadenitis was not in the neck, or if caused by …

Automating A Well Child Visit, Daniel Merrill

Research Days

No abstract provided.

Social Capital And Cross-Boundary Collaboration In Wyoming Wildfire Management Networks, Hannah L. Spencer, Christian Heisler

Student Research Symposium

Wildfire hotspots often intersect jurisdictional boundaries, so protecting human communities and restoring healthy fire regimes will require collaborative, cross-boundary action from fire managers. However, collaboration between fire management groups can have varied outcomes depending on the actors involved, all with different missions, financial obligations, and cultures. One way to conceptualize the interactions between actors is with the idea of social capital. We will investigate the following research question: how does social capital impact cross-boundary collaboration in wildfire management networks? We will survey wildfire managers in northwestern Wyoming about their collaborative actions using a snowball sampling method. Using Social Network Analysis …

Investigation Of The Externship Selection Process Across Asha-Accredited Speech Language Pathology Programs, Teale Niles, Lindsey Schwab, Brandon Eddy

Student Research Symposium

Graduate students in speech-language pathology (SLP) must complete 400 clinical clock hours during graduate training, the majority of which frequently come from off-campus externship experiences. Graduate students are matched to externship sites by their program. No studies to date have systematically documented how graduate programs in speech-language pathology select students for externship experiences nor the constraints involved in the externship process (e.g., academic schedule). The goal of this study is to survey ASHA accredited SLP programs to describe the current procedures being used to place students at externship sites and the roles and perspectives of the externship coordinators. Externship coordinators …

Comparison Of Heavy Metals In Spinach Grown On The Roof Ground Location At Portland State University, Tyler A. Robin

Student Research Symposium

As a result of urbanization, fresh, healthy food can be expensive and easily contaminated but space for local farming is limited. Roofs can be underutilized in densely populated cities and can offer a space for local fresh farming. The purpose of this study is to continue a previous study done in 2021, to find if growing leafy vegetables on the roof can limit heavy metal exposure from air pollutants. This study compares spinach grown on the roof in 2021, 2019 and spinach bought from stores around the Portland State University campus and the heavy metals found in these greens. The …

Surface Plasmon Characterization In Ag Nanotriangles For Evaluation Of Fano Resonance Conditions, Nabila Islam

Student Research Symposium

Surface plasmon polariton (SPP) is a collective oscillation of electrons and light at the metal -dielectric interface excited by the incident radiation on metal surface through the momentum matching conditions. The properties of SPPs and the resonance conditions are highly dependent on the confining materials and geometry of the confining nanostructure. The sensitivity of the surface plasmon resonance to the property of the confining materials made Surface plasmon resonance (SPR) sensors a central tool for biosensing. However, the frequency resolution of SPR sensors is typically limited by the broad resonance of the SPR mode. The resolution can be enhanced through …

Augmentative And Alternative Communication Course Design And Features: An Analysis Of Course Syllabi And Calendars, Celine Goodbody, Hosanna Broderick, Brandon Eddy

Student Research Symposium

Augmentative and alternative communication (AAC) is an area of clinical practice that supplements or compensates for impairments in speech-language production and/or comprehension (ASHA, n.d.). A survey study by Johnson and Prebor (2019) found 86% of graduate speech-language pathology (SLP) programs offered an AAC course, though half (49%) suggested their students were underprepared to provide AAC services. High-quality graduate training, including AAC coursework, has been suggested as a solution to prepare clinicians to provide AAC services. Recently, Sauerwein and Burris (2021) surveyed AAC course instructors at accredited SLP graduate programs to analyze AAC course design features. Sixty-four (24.2%) programs responded to …

Memristors, Memcapacitors And Their Application In Neuromorphic Computing, Nithyakalyani Sampath

Student Research Symposium

Data-intensive computing operations, such as training neural networks, are essential but energy-intensive. Memcapacitance and memristance,which can be described as capacitance and resistance, with “memory”, are properties of semiconductor devices that are observed on the nano-scale. These properties allow for data storage without a constant source of power, leading to hardware which is more energy efficient.

We intend to demonstrate that we can build specialized hardware onto which a neural network can be directly mapped using memristors and memcapacitors, improving the energy efficiency of the network. We will use Simulation Program with Integrated Circuit Emphasis (SPICE) to model our memcapacitor and …

Characterizing The Functional Role Of Transcription Factor E In Archaeal Transcription, Madolyn Hofstetter, Michael Bartlett

Student Research Symposium

Archaea and eukaryotes share many homologous proteins and essential mechanisms for survival and DNA replication. It is proposed that Archaea are the ancestors of eukaryotes, suggesting that eukaryotic transcription evolved from the basic archaeal mechanisms. By studying the fundamentals of archaeal transcription, we are in turn understanding more about how eukaryotic transcription functions. Many human diseases are linked to mishaps and mutations in the process of transcribing DNA to mRNA, so it is essential to explore structures and how mutations in these structures affect the essential function of transcription, and if these mutations also play a role in human disease.

Effect Of Sin Lek Rice Intervention On Cognitive Function, Dietary Patterns, And Fecal Microbiota Of Elementary School Children In Chiang Rai, Thailand, Angie Setthavongsack, Siam Popluechai,, Jackilen Shannon, Justin Denny, Eleni Gentekaki, Kongkiat Kespechara, Lucky Gruneck, Thomas J. Sharpton, Eddie Niwed, Lisa K. Marriott

Student Research Symposium

I will be speaking about our ongoing project with OHSU and Mae Fah Luang University about the effects of a highly fibrous rice called “Sin Lek” and the changes it will do to both the gut microbiome and cognitive function. My data analysis focuses solely on memory, attention span, and impulsivity on Thai schoolchildren. The poster will document baseline data and it’s outcomes, along with brief information about Dr. Siam Popluechai’s lab findings on certain microbiome species. I will also be going in depth about the area of the study, along with how these were tested such as explaining the …

Visualization Of Eye Development In Annual Killifish Using Whole-Mount Immunohistochemistry, Carmen Z. Rodriguez, Jason Podrabsky

Student Research Symposium

Vertebrate eye development is highly conserved. Current models have identified the gene networks involved in eye development, but lack the context of extreme environmental conditions that challenge these fundamental programs. Typical vertebrates live for many years while annual killifishes can complete their entire adult lifespan in a matter of weeks. Thus, annual killifishes are a strong model for age-related diseases such as age-related macular degeneration (AMD); an irreversible loss of central vision. Annual killifishes enter embryonic diapause; a period of developmental and metabolic dormancy. These embryos are extremely resistant to environmental stresses such as hypoxia/anoxia that would cause irreparable damage …

Growing Reservoir Networks Using The Genetic Algorithm Deep Hyperneat, Nancy L. Mackenzie

Student Research Symposium

Typical Artificial Neural Networks (ANNs) have static architectures. The number of nodes and their organization must be chosen and tuned for each task. Choosing these values, or hyperparameters, is a bit of a guessing game, and optimizing must be repeated for each task. If the model is larger than necessary, this leads to more training time and computational cost. The goal of this project is to evolve networks that grow according to the task at hand. By gradually increasing the size and complexity of the network to the extent that the task requires, we will build networks that are more …

Survey Of The Bees And Floral Use At The Leach Botanical Garden, Joshua Page

Student Research Symposium

There have been few studies of the diversity of bee species found in Oregon’s urban areas, and fewer studies that have systematically examined how bee populations change over the seasons. A survey of native bee populations at the Leach Botanical Gardens was conducted to determine what bees were present, how they changed over the season, and what flowers they used. Biweekly over the 2020 and 2021 bee seasons, sections of the garden were sampled in 30 minute equal time intervals, divided among the patches of flowering plants on which bees were observed. Bee specimens were captured with collection vials on …

Mapping Ecosystem Service Flows Of Estuary Restoration Projects On The Oregon Coast To Identify Impacted Stakeholders, Shersten Finley

Student Research Symposium

Restoration of largely depleted estuarine systems is increasingly recognized as key to solving a variety of problems coastal communities face currently. Many of these issues will become more acute with climate change and sea level rise. Historic losses of estuary area, and recognition of the ecosystem services provided by functioning estuary ecosystems have resulted in current impetus to pursue estuary restoration. By mapping the flows of ecosystem services using three ecosystem service ‘scorecard’ categories pertaining to coastal resource management: recreation, aesthetics, and cultural/historical/spiritual, we gain a better understanding of the populations impacted by the changes in flows of ecosystem service …

Simple Arenes As Aryne Synthetic Equivalents Via Sulfonium Salt Intermediates, Riley A. Roberts

Student Research Symposium

Arynes are ephemeral molecules that are yet to be fully exploited in synthetic strategy because they are often challenging to access. These reactive intermediates participate in a myriad of reactions that conventional chemistry is incapable of, making them extremely useful for the synthesis of important molecules like pharmaceuticals and agrochemicals. While classical approaches for synthesizing arynes employ cheap starting material, extremely harsh reagents are necessary to generate the aryne. In contrast, methods that do not require harsh reaction conditions do require starting material that is exceedingly difficult to synthesize. To access arynes quickly and efficiently, the work described herein aims …

Factors Impacting Heritage Language Maintenance In Children, Helena Sai

Student Research Symposium

This review article aims to examine families’ beliefs and strategies regarding heritage language maintenance in the US. Language status, caregiver beliefs, and community factors are explored in relation to language maintenance across generations. The broader context in which parents make decisions about family language policies were investigated through the following research questions:

1. What is the nature of the relationship between a heritage language’s language status in society and language maintenance across generations?

2. How do parents’ beliefs about the impact of heritage language on academic, social, and career success influence their decision to pass this language to their children?

3. To what …

   ---

   Go to article