Digital Commons Network^™

Covalent Modification Of Recombinant Protein With Reactive Thiols, Sawyer Dulaney, Bailey Taylor

Honors Theses

Many diseases cause chronic and painful inflammation in different body systems. One of the front-line drug classes to treat such inflammation is Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Despite the benefits of oral administration of NSAIDs, there are drawbacks to their long-term usage because they can cause detrimental effects on off-target systems in the body such as the liver, kidney, or the lining of the intestinal tract. An alternative to NSAIDs is the usage of hydrogels for targeted drug delivery. Hydrogels can provide drug delivery in a specific portion of the site of inflammation, thus allowing higher doses of medication to be …

Optimization Of A Fluidized Bed Reactor For The Production Of Styrene From Ethylbenzene, Gregory Espenan

Honors Theses

In order to optimize Unit 500, a styrene production plant, the Net Present Value (NPV) was used as the objective function to ensure every optimization strategy had a positive economic effect. To optimize a chemical plant, it is important to note efficiency, economics, product specifications, and production requirements. The goal of this project was to make changes to the base case of Unit 500 to minimize the cost to produce styrene for an upstream unit. PRO/II was used to simulate various points in different unit operations throughout the process. The NPV was measured after each unit operation was simulated to …

The Effects Of Crowding Agents On The Pka Of Physiologically Stable I-Motif Dna, Courtney Turner

Honors Theses

The overall goal of this thesis was to investigate the environmental conditions that induce i-Motif folding of the DNA strand DUX4L22, a cytosine-rich segment of DNA found in the human genome. Cellular conditions were simulated using sodium cacodylate buffer and multiple weights of polyethylene glycol as a crowding agent. The presence of i-motifs were confirmed by Circular Dichroism spectroscopy. I found that DUX4L22 does form i-motifs under these physiological simulations at both acidic and neutral pHs. DUX4L22 therefore shows potential for use in studies of a wide variety of biotechnological advances, such as regulatory switches in nanomachines or drug-delivery systems.

The Influence Of Culture On The Accounting Profession: An Investigation Into The Implementation Of The Oecd's Inclusive Framework On Beps In The United States And Germany, Vivian Francis

Honors Theses

This research investigates the United States and Germany’s implementation of the OECD’s Inclusive Framework on BEPS and assesses the degree to which each country’s response was influenced by its culture. The objective of this research is to present a perspective on how international accounting regulations can take cultural characteristics into consideration in order to produce their desired outcomes. For the purpose of this thesis culture is defined and quantified through the framework developed by Geert Hofstede. Furthermore, this thesis investigates the relationship between the neoliberal political paradigm and the role of culture in accounting. This research uses a combination of …

Confronting Stigma: Ethical Leadership, Influence, And The Dignity Of People Struggling With Addiction, Jacob Fennell

Honors Theses

People struggling with addiction in the United States of America deserve better treatment. The current stigma of people struggling with addiction as moral failures perpetuates a policy of drugs that sees them as criminal. This policy should be repealed and a better culture of care should be created. People struggling with addiction deserve a standard of treatment based on the core tenet of human dignity. In engaging with the history and cultural beliefs that are the foundation of this mistreatment, this same tenet of dignity must be upheld. This specifically comes into my project when exploring methods of changing these …

American Goldfinches (Spinus Tristis): Changes In Behavior During Mycoplasma Gallisepticum Infection, Hetal Shingrani

Honors Theses

Animal sickness behavior is an important component of disease ecology and is essential to understanding wildlife diseases and how and where animals allocate resources for survival. This study examines sickness behaviors, the extent of conjunctivitis, and the presence of an antibody response in relation to a Mycoplasma gallisepticum (MG) respiratory infection in American goldfinches. We conducted an experimental infection of American goldfinches and recorded behavior videos, and collected blood samples, throat swabs, eye swelling, and mass data at multiple time points throughout the experiment. An ELISA-serum assay was run after the conclusion of the study to identify the presence of …

The Design Of A Pcr-Based Assay To Detect And Isolate The Serine Palmitolytransferase Gene From Environmental Bacteria, Lana Taylor

Honors Theses

Sphingolipids are a natural class of lipids that function as structural elements of cell membranes and signaling molecules for important cellular activities such as cell growth, differentiation, apoptosis, recognition, and adhesion. These lipids can be found universally in eukaryotic cells as well as some species of bacteria, such as those found in the human gut microbiome and in the environment in soils. Though sphingolipid production is rare in bacteria, both eukaryotic and prokaryotic sphingolipid biosynthesis begin with the condensation of serine and palmitoyl CoA into 3-ketodihydrosphingosine catalyzed by the enzyme serine palmitoyltransferase (SPT). In recent years, several studies have shown …

Individual Beef Cattle Identification Using Muzzle Images And Deep Learning Techniques, Guoming Li, Galen E. Erickson, Yijie Xiong

Department of Animal Science: Faculty Publications

The ability to identify individual animals has gained great interest in beef feedlots to allow for animal tracking and all applications for precision management of individuals. This study assessed the feasibility and performance of a total of 59 deep learning models in identifying individual cattle with muzzle images. The best identification accuracy was 98.7%, and the fastest processing speed was 28.3 ms/image. A dataset containing 268 US feedlot cattle and 4923 muzzle images was published along with this article. This study demonstrates the great potential of using deep learning techniques to identify individual cattle using muzzle images and to support …

Wiley Family Papers (Sc 3637), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid and scans (Click on "Additional Files" below) for Manuscripts Small Collection 3637. Weather summary for 1936 by Ed Wiley, Summer Shade, Kentucky; weather summary for January-February 1951 by his daughter Nina; and memoranda of animal remedies, 1937, and roofing expenses, 1939.

Senior Farewell: Anna Kate Munsey, Anna Kate Munsey

Digital Edition

An independent student produced newspaper from the University of New Hampshire.

The Knowledge, Attitudes, And Practices Of Faculty Towards Scholarly And Predatory Open Access Publishing, Julie H. Schiavo

Library Faculty Publications

No abstract provided.

Making Rules Vs Ruling, Ramsi Woodcock

Law Faculty Popular Media

In an effort to fight inflation, the Federal Open Market Committee raised interest rates to 20% over the course of 1980 and 1981, triggering a recession that threw more than 4 million Americans, many in well-paying manufacturing jobs, out of work.

As it continues to do today, the committee met in secret and explained its rate decisions in a handful of paragraphs.

None of the millions of Americans thrown out of work—or the many businesses driven to bankruptcy—sued the FOMC. No one argued that the FOMC’s power to disrupt the American economy was an unconstitutional delegation of legislative authority. No …

Male Song Stability Shows Cross‐Year Repeatability But Does Not Affect Reproductive Success In A Wild Passerine Bird, Alexander Hutfluss, E Bermúdez‐Cuamatzin, Alexia Mouchet, Mark Briffa, Hans Slabbekoorn, Niels J. Dingemanse

School of Biological and Marine Sciences

No abstract provided.

Focus On Top Tier 2.0 - Unlv Health, University Of Nevada, Las Vegas

Focus on Top Tier 2.0

UNLV Health seeks to create a healthier Nevada by caring for our communities and by driving the future of healthcare; it will transform the way that care is delivered in Southern Nevada. UNLV's five health science schools (Medicine, Dental Medicine, Public Health, Nursing, and Integrated Health Sciences), along with programs in behavior and mental health, are working together utilizing a model of comprehensive care where those who seek care are provided with a range of highly trained healthcare providers in a single visit.

Micro-Metropolis: Space, Work, And Waste In The Maquettes Of Constant And Bodys Isek Kingelez, Shoshanah B. Rosen

Theses and Dissertations

Constant Nieuwenhuys and Bodys Isek Kingelez both create futuristic utopias in the form of architectural maquettes. This comparative study explores each artist’s reverence for technology, global connectivity, and new forms of economic production. It argues that these utopias represent desires endemic to late modernity and capitalism, including consumption, nomadism, automation.

Galvanizing Steel, Francesca Dominguez

Theses and Dissertations

This paper examines Galvanizing Steel, a performance event through the lens of John Martin’s concept of “metakinesis,” Dominguez considers spectatorship and interpretation as active participation. She queries kinesthetic empathy and whether centering the corporeal experience of the audience enhances their overall ability to connect with the performers and the performance.

“Paint What You Hate”: Philip Guston’S Hooded Figures And The Postponement Of The Exhibition Philip Guston Now, Thomas Baldwin

Theses and Dissertations

This thesis interrogates the postponement of the Philip Guston Now exhibition, examining the justification for the postponement, the actions taken by the National Gallery of Art, and the effects of the postponement. My research examines the museum’s choice to cite social justice as the main context for understanding Philip Guston.

Sondra Perry: On The Limits And Possibilities Of Access, Visibility, And Freedom, Sigourney Schultz

Theses and Dissertations

Sondra Perry: On the Limits and Possibilities of Access, Visibility, and Freedom connects the intellectual history of cyberfeminism and Afrofuturism with the future of post-Black studies by exploring themes such as the abstraction of blackness and the materiality of new media.

Formations Of The Mayan Diaspora In Guatemala And The Us: Land, Migration, And Linguistic Ideologies As The Markers Of Diasporic Separation., Daniel Antipov

Theses and Dissertations

This work examines the phenomenon of diaspora formation among the indigenous Guatemalan population as a major identity marker in the new Guatemalan immigrants in the US. This work provides: definition of diaspora, its historical frames, juxtaposition of the self and the Other, and separation and differentiation of the indigenous languages

Unusual High-Frequency Mechanical Properties Of Polymer-Grafted Nanoparticle Melts, Mayank Jhalaria, Yu Chang, Yucheng Huang, Brian C. Benicewicz, Sanat K. Kumar, George Fytas

Faculty Publications

Brillouin light spectroscopy is used to measure the elastic moduli of spherical polymer-grafted nanoparticle (GNP) melts as a function of chain length at fixed grafting density (0.47  chains/nm²) and nanoparticle radius (8 nm). While the moduli follow a rule of mixtures (Wood’s law) for long chains, they display enhanced elasticity and anomalous dissipation for graft chains <1⁢0⁢0  kDa. GNP melts with long polymers at high 𝜎 have a dry zone near the GNP core, surrounded by a region where the grafts can interpenetrate with chain fragments from adjacent GNPs. We propose that the departures from Wood’s law for short chains are due to the effectively larger silica volume fraction in the region where sound propagates—this is caused by the short, interpenetrated chain fragments being pushed out of the way. We thus conclude that transport mechanisms (of gas, ions, sound, thermal phonons) in GNP melts are radically different if interpenetrated chain segments can be “pushed out of the way” or not. This provides a facile new means for manipulating the properties of these materials.

Class Of 22 Spotlight: Charles Westerhaus, Jd, James Owsley Boyd

Keep Up With the Latest News from the Law School (blog)

No abstract provided.

Cotton/Soybean Insect Newsletter, May 4, 2022, Jeremy K. Greene

Clemson University Cotton/Soybean Insect Newsletter

No abstract provided.

Student Recital - Auriyan Tillman, Auriyan Tillman

Bailey School of Music Concert Programs

Student Recital program

Student Recital - Grady Housworth, Grady Housworth

Bailey School of Music Concert Programs

Student recital program

The Lumberjack, May 04, 2022

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Sexual Relationships During Covid-19, Katherine Hahn-Boisvert

Honors Capstones

During the early parts of COVID-19, no one knew what to expect. In a world where it was suddenly unacceptable to shake hands or give a hug, how did sexually intimate couples navigate being sexually intimate? In this study, sexual self-disclosures, relationship satisfaction, and sexual communication satisfaction were measured during the COVID-19 pandemic. The costs and rewards of COVID-19 related self-disclosures was also measured to see what people thought was the costliest and how it would impact a sexually intimate relationship. Data was collected using an online survey which had 15 participants. The results indicated that COVID-19 had a negative …

Silver Bow Creek/Butte Area Npl Site Butte Priority Soils Operable Unit, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Downfalls Of Economy Leading Small Businesses: A Study Of Corrective Actions, Alexis N. Davis

Honors College Theses

This study explores the significance of inappropriate accounting procedures and their detrimental effects on small businesses. This conceptual study is centered around small business decisions made by decision makers with weak understanding of financial literacy. The study highlights a series of improvements to weak internal controls that are not uncommon in small businesses.

Defund The Police: Snappy Slogan Or A Viable Solution? A Case Study Of Savannah, Georgia, Michayla F. Knox

Honors College Theses

The notion of defunding the police remains a hot-button political topic since the protests of Summer 2020. The forefront of the debate concerns how defunding the police will impact crime rates. Still, the topic has scarcely been investigated empirically. This thesis provides an early examination into the relationship between "defunding the police", reallocating funding, and crime rates in Savannah, Ga. Several experiments are performed to answer three research questions that involve comparing and manipulating the budget provided for policing and the budgets for neighborhood vitality and poverty reduction. The findings show that Savannah allocates significantly more money to the policing …

Student Perceptions Of Gendered Racial Microagressions, Ayanna Brewton

Honors College Theses

The impact of stereotypes, prejudice, and discrimination is a widespread issue in society that has become more visible to people with privilege and has been more widely studied by social scientists and mental health professionals. More recently, the impact of gendered racial microaggressions has been investigated. Gendered racial microaggressions are defined as indirect and everyday slights and insults based on the intersection of racism and sexism (Gadson & Lewis, 2021). Research shows that gendered racial microaggressions toward multiple minority status individuals has a negative impact on their mental wellbeing (Mekawi & Todd, 2018). However, there is a gap in the …