Digital Commons Network^™

The Importance Of Proximal Non-Obstructive Plaque For Predicting Risk Of Future Acute Coronary Syndrome In Stable Cad: Prognostic Value Of Coronary Ct Angiography, Har R. S. Dhillon, Hilfan A. P. Lubis, Yuke Sarastri, Andre P. Ketaren, Teuku B. Haykal

Journal of the Hong Kong College of Cardiology

Objective: To evaluate the prognostic value of proximal non-obstructive coronary plaques detected by coronary computed tomography angiography (CCTA) in predicting acute coronary syndrome (ACS) among patients with stable coronary artery disease (CAD). Methods: This retrospective cohort included patients with stable CAD who underwent CCTA at Adam Malik General Hospital, Medan, between January and December 2023. Of 458 patients with non-obstructive plaques, 416 met inclusion criteria and were followed for 18 months. Patients were classified into proximal involvement (left main, proximal left anterior descending artery, proximal left circumflex artery, or proximal right coronary artery) and non-proximal groups. The primary endpoint was …

Venous Thromboembolism Attenuates Brain Cortical Thickness: Evidence From Mendelian Randomization Study, Wenli Gu, Xiu Liu, Christopher Tze-Wei Tsang, Si Yeung Yu, Yan Chen, Jiayi Huang, Yuk Ki Yukie Lam, Tim Yan, Meizhen Wu, Ran Guo, Jingnan Zhang, Ferit Böyük, Yap Hang Chan, Kai Hang Yiu

Journal of the Hong Kong College of Cardiology

Background: Emerging evidence suggests an association between vascular risk factors and changes in brain cortical structure and function. However, the relationship between venous thromboembolism (VTE) and brain cortical remodeling remains unclear, impeding further research on brain cortical dysfunction. Methods: Using summary statistics obtained from genome-wide association studies (GWAS), we conducted two-sample Mendelian randomization (MR) analyses to explore potential causal effects of genetically predisposed pulmonary embolism (PE, N = 361,194), deep vein thrombosis (DVT, N = 462,933) and unspecified VTE (N = 218,792) on brain cortical structure (N = 51,665). Magnetic resonance imaging (MRI)-based measures of brain cortex including …

The Link Between Atrial Fibrillation And Gastroesophageal Reflux Disease - Pathophysiology, Emerging Evidence And Treatment Options, Wojciech Jakub Bajda, Jakub Juszczyk, Negin Fani, Dongwoo Kang, Jerzy Gregorczyk

Journal of the Hong Kong College of Cardiology

Gastroesophageal reflux disease (GERD) and atrial fibrillation (AF) are common conditions that significantly impact gastrointestinal and cardiovascular health. Emerging evidence suggests a bidirectional relationship between these conditions, mainly driven by inflammation and vagal nerve stimulation. Shared risk factors include obesity, obstructive sleep apnea, and hiatal hernias. This review explores the underlying pathophysiological mechanisms that may link GERD and AF, focusing on the roles of autonomic dysregulation, systemic inflammation, and mechanical interactions that may cause symptoms for both diseases. Lifestyle modifications including weight management, along with pharmacological treatments like proton pump inhibitors, have shown promise in managing the symptoms of both …

Approach To Management Of Grown-Up Cyanotic Congenital Heart Disease, Pak-Cheong Chow

Journal of the Hong Kong College of Cardiology

Despite of advances in cardiac and surgical care, some children with complex congenital heart disease remain cyanotic in adulthood. The grown-up cyanotic congenital heart diseases are heterogeneous due to their underlying cardiac anatomy and physiology. Other than cardiovascular problems, they patients are also faced with multi-system complications in the long run. Therefore, these patients need nuanced and comprehensive assessment, regular follow-up monitoring, and multi-facet management. In this article, the types and classification of cyanotic congenital heart diseases, the multi-system complications and the approach to assessment and treatment will be presented.

Mcconnell Caught In 3d: Comparison With Other Etiologies Of Right Ventricular Failure, Shing Ching, Karl Chan

Journal of the Hong Kong College of Cardiology

The McConnell sign is a well-recognized 2D echocardiographic feature of pulmonary embolism characterized by apparent hypokinesia of right ventricular mid and apical free wall segments. However, it is rarely described in 3D echocardiography. We report a case of high-risk pulmonary embolism with the McConnell sign demonstrated in 3D echocardiography. Comparison with other etiologies of right ventricular dysfunction regarding 3D morphology and 2D speckle tracking strain is also discussed.

Non-Hermitian Sl (3, C) Three-Mode Couplers, B. M. Rodríguez-Lara, Hamed Ghaemi-Dizicheh, Shahram Dehdashti, Andreas Hanke, Ahmed Touhami, J. Nötzel

Physics & Astronomy Faculty Publications

Photonic systems with exceptional points, where eigenvalues and corresponding eigenstates coalesce, have attracted interest due to their topological features and enhanced sensitivity to external perturbations. Non-Hermitian mode-coupling matrices provide a tractable analytic framework to model gain, loss, and chirality across optical, electronic, and mechanical platforms without the complexity of full open-system dynamics. Exceptional points define their spectral topology, and enable applications in mode control, amplification, and sensing. Yet N -mode couplers, the minimal setting for N th-order exceptional points, are often studied in specific designs that overlook their algebraic structure. We introduce a general sl(N , C) framework for arbitrary …

Komparatibong Analisis Sa Estetikong Danas Na Hatid Ng Koreanobela At Filipinobela Ayon Sa Mga Pilipinong Manonood, Christine Morit

Mabini Review

The paper highlights a thorough discussion of the vast influence and prominence of Korean dramas (Koreanobela) in the Philippines, which has become a central focus among critics in the discourse of film and television. Their rise in popularity has fostered an appreciation for both local and foreign spaces that continue to shape and influence Filipino culture. Although the importation of films from Latin American countries—an influence rooted in Spanish colonization—is not new in the Philippines, the unparalleled appeal of Korean dramas in capturing the attention of Filipino audiences cannot be denied. To identify the reasons behind this fascination, the researcher …

Recognizing The 50th Anniversary Of The Robert F. Wagner National Labor And Employment Law Moot Court Competition, Jennifer Bancamper

NYLS Community News

No abstract provided.

Book Review Of Hidden Suicides And Fatal Overdoses: A Forward Path Author: Ian Rockett. Johns Hopkins University Press: Baltimore. 2026. 271 Pages., Roger Clark

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

The Roles Of The Human Resources Management Director And Their Impact On Entrepreneurial Training:An Analytical Study At The Ministry Of Labor And Social Affairs, Ali Abd Al-Salam Abd Al-Daem

Muthanna Journal of Administrative and Economics Sciences

The research problem lies in the weak level of entrepreneurial training in Iraqi ministries despite the importance of the strategic roles of human resources management. The research gap is represented by the scarcity of empirical studies that measure the relative impact of the roles of the HR manager (according to Ulrich’s model) in activating entrepreneurial training within the Iraqi public sector environment. Accordingly, this study aims to analyze the relationship between the roles of the Human Resources Management Director—as a strategic partner, administrative expert, developmental supporter, and change agent—and their impact on activating entrepreneurial training at the Ministry of Labor …

Analyzing The Impact Of Applying Ipsas 42 On Social Benefits In Enhancing Reporting Quality And Promoting Financial Sustainability, Burhan Hussein Khalaf Al-Rawi, Hasan Saleh Yusuf Al-Bajari

Muthanna Journal of Administrative and Economics Sciences

The study aims to explore the impact of applying IPSAS 42 on social benefits in enhancing the efficiency of financial reporting and strengthening the sustainability of financial capabilities within Iraqi government institutions. The study objectives were achieved by examining the nature and objectives of IPSAS 42, assessing the current state of disclosure of social benefits in government financial reports, and measuring the extent to which the social benefits standard contributes to promoting financial sustainability. The study relied on secondary financial data from a set of Iraqi government entities, including current expenditures, capital/investment expenditures, oil revenues, non-oil revenues, fiscal deficit, and …

The Impact Of Corporate Governance Practices On Enhancing The Quality Of Financial Reporting: An Applied Study On A Sample Of Commercial Banks Listed On The Iraq Stock Exchange, Ahmed Hashem Sakr

Muthanna Journal of Administrative and Economics Sciences

This study examines the impact of corporate governance practices on the quality of financial reporting in a sample of commercial banks listed on the Iraq Stock Exchange. Motivated by the increasing need for transparency and reliability in financial information within the Iraqi banking environment characterized by regulatory challenges and economic instability the research investigates how key governance mechanisms contribute to enhancing the credibility and accuracy of financial reports. The study focuses on three core governance indicators: board size, board independence, and audit committee activity, in addition to relevant control variables reflecting firm characteristics.Employing panel data analysis and fixed-effects regression models, …

Human Resource Flexibility And Its Role In Organizational Ambidexterity: An Analytical Study At The General Company For Electrical And Electronic Industries, Hanaa Nassrullah Khamees Alhamadani

Muthanna Journal of Administrative and Economics Sciences

This research aims to analyze the role of human resource flexibility in achieving organizational Ambidexterity at the General Company for Electrical and Electronic Industries. This stems from the importance of flexibility as a fundamental factor enabling organizations to adapt quickly to rapid environmental changes and enhance their competitiveness. The research adopted a descriptive-analytical approach, and data were collected from a random sample of (75) employees working in administrative and technical departments related to the study topic. The independent variable was human resource flexibility with its three dimensions (skill flexibility, behavioral flexibility, and human resource practices flexibility), while the dependent variable …

The Role Of Organizational Resilience In Reducing Organizational Collapse: An Analytical Study Of The Opinions Of A Sample Of Workers In The Tal Afar Education Department, Shuab Ahmed Aziz Al-Mawla

Muthanna Journal of Administrative and Economics Sciences

Purpose: This research aims to study the relationship between organizational resilience (capital resilience, strategic resilience, cultural resilience, learning resilience, and relationship resilience) and organizational breakdown (internal factors, external factors, structural factors, human factors, and financial factors) in the Tal Afar Education Department, Nineveh Governorate. Design/Methodology: Based on stratified random sampling, 400 questionnaires were distributed from a population of 650 to employees of the Tal Afar Education Department. The sample was drawn using Sakran’s (2010) formula. A similar questionnaire was also distributed to principals and assistant principals working in affiliated schools. Of these, 191 questionnaires were deemed valid. The …

Human Talent Management And Its Role In Enhancing The Quality Of Educational Service: An Exploratory Study Of The Opinions Of A Sample Of Supervisors In The General Directorate Of Education Of Nineveh, Ibrahim Khalil Ibrahim Mohammed Al-Hayali

Muthanna Journal of Administrative and Economics Sciences

This research aims to examine the actual role reflected by human talent management, specifically its dimensions (recruitment, performance management, training and development, talent retention), in enhancing the quality of educational service, which includes (the academic background of the teacher, the curriculum, infrastructure and facilities, quality of recruitment, safety and security, development of students’ skills). The research stems from a real problem whose features are embodied in the following question: What is the actual role reflected by the dimensions of human talent management in enhancing the quality of educational service in the researched directorate? Using the descriptive-analytical approach to diagnose and …

Blockchain Technology As A Tool To Enhance Information Security Elements In The Government Organizations Sector: An Exploratory Study In The Nineveh Governorate Traffic Directorate, Saif Khalid Zakaria

Muthanna Journal of Administrative and Economics Sciences

Purpose: The objective of this study is oriented to investigate what are the determinant features of Blockchain Technology (BCT) that contribute in boosting ISE factors in governmental institutions. The research work is grounded on referring to the most popular features of Blockchain (BC) in enhancing the core and supportive (ISE). Research Design/ Methods and approach: The data for this research was based on a crosssectional and correlational survey (95 responses were finally analyzed). The collected data were first analyzed using SPSS v.26 and then through variance based structural equation modeling (SEM; Smart PLS v.4) for assessing validity and …

His Role In Government Investment In Economic Development Services In Iraq, Hatem Jabr Atshan

Muthanna Journal of Administrative and Economics Sciences

This study aims to shed light on the reality of government investment spending in Iraq by analyzing its indicators and estimating the government investment spending index and its impact on economic growth for the period 2004-2024, based on theoretical and applied frameworks. The study concluded that the contribution of investment spending to GDP was determined to be between (5.7%) and (69.6%), with an average rate of (17.75%), indicating government involvement in socio-economic fields. There is no financial approach worldwide that reduces the scope of public spending in favor of investment spending in a way that leads to increased economic growth.

Integrated Reporting And Its Role In Enhancing The Reliability Of Financial Reports: The Mediating Role Of Digital Transformation Technology: A Field Study, Mohammed Jumaah Kareem Sajet Al-Barki, Qasim Mohammed Abdullah, Majid Gazi Hasan, Ali Awadh Atshan

Muthanna Journal of Administrative and Economics Sciences

The primary objective of the research is to demonstrate the impact of Integrated Reporting on enhancing the reliability of financial reports through the adoption of digital transformation technology, and to provide the cognitive foundations regarding Integrated Reporting and the reliability of financial reports. The research focused on the community of commercial companies listed on the Iraq Stock Exchange, with the sample limited to seven (7) companies according to specific criteria, as they are listed on the exchange and possess externally audited financial reports. These companies did not experience any mergers during the research period, which allowed for the completion of …

Application Of A Fuzzy Multi-Objective Defuzzification Method To Solve A Multi-Modal Transportation Problem, Qusay H Khalaf, Khalid Zeghaiton Chaloob

Muthanna Journal of Administrative and Economics Sciences

Multi-modal transportation systems are the logistics networks for global economy. Transportation systems are fraught with uncertainties that hinder the traditional deterministic models reaching the optimal performance. The main obstacle for traditional deterministic models is the uncertainties (e.g., fuel prices volatility, inaccurate transit-times prediction, and evolving environmental regulations). This paper proposes a novel method of fuzzy multi-objective defuzzification. It integrates a modified center of gravity (COG) technique with multi-objective linear programming (MOLP) to address the uncertainty challenges. Triangular fuzzy numbers and partitioning to sud-intervals generated crisp solutions to balance conflicting objectives: cost, time, and environmental sustainability. A four transportation-mode used as …

The Role Of Digital Governance In Improving The Quality Of Financial Reporting Under Fair Value Measurement In Accordance With International Financial Reporting Standard (Ifrs 13): An Applied Study On Jordanian Banks Listed On The Amman Stock Exchange., Ashraf Hashim Faris Alabdoon

Muthanna Journal of Administrative and Economics Sciences

This study investigates the role of digital governance in enhancing the quality of financial reporting, while examining the mediating effect of fair value measurement under IFRS 13. The study is based on the hypothesis that digital governance practices have a positive impact on improving financial reporting quality within the fair value measurement framework. The empirical analysis focuses on Jordanian commercial banks listed on the Amman Stock Exchange over the period 2017–2024. Data were collected from published annual financial reports to construct a dataset suitable for statistical analysis and to bridge theoretical concepts with practical applications in the banking sector. The …

Ketone Body Supplementation Exerts Renoprotective Effects Against Adenine-Induced Kidney Injury Via Oxct1-Mediated Ketolysis In Mice, Shoji Omachi, Sho Sugahara, Junya Horiguchi, Mako Yasuda-Yamahara, Shogo Kuwagata, Kosuke Yamahara, Yuki Tanaka-Sasaki, Shogo Ida, Tetsuro Kusaba, Benjamin D Humphreys, Kenji Kufukihara, Jin Nakahara, Masami Chin-Kanasaki, Shinji Kume

2020-Current year OA Pubs

Ketone bodies have traditionally been recognized as glucose-sparing energy sources, with hepatic ketogenesis and peripheral ketolysis serving pivotal functions in maintaining energy homeostasis during fasting. Although they are commonly seen as harmful due to their link with ketoacidosis, recent studies emphasize their roles in organ protection. This has sparked interest in their possible use as a treatment for chronic kidney disease (CKD). In this study, we examined both exogenous and endogenous ketone body supplementation in adenine-induced kidney injury in mice. Supplementation with the ketone body precursor 1,3-butanediol significantly improved adenine-induced renal fibrosis, inflammation, and apoptotic cell death. However, genetically deleting …

Feasibility Of High-Intensity Interval Training In Older Adults With Hiv And Co-Occurring Hypertension, Michael J Hankes, Taylor L Taylor, Emily L Zumbro, Ene M Enogela, Fitzgerald Dodds, Mckenna Tharpe, Silvienne C Sint Jago, Burel R Goodin, Amanda L Willig, Thomas W Buford, Raymond Jones

2020-Current year OA Pubs

BACKGROUND: As life expectancy for people living with HIV (PWH) has increased, there has been a rise in age-related comorbidities such as hypertension. Exercise is an important nonpharmacological strategy to counter such adverse effects of chronic HIV infection. High-intensity interval training (HIIT) has been demonstrated to be safe and efficacious in improving health outcomes in individuals with chronic illness, but data are limited in older PWH and co-morbid conditions. The primary objective of this pilot feasibility study was to assess the feasibility, efficacy, and safety of a 6-week HIIT intervention among older PWH and co-occurring hypertension.

METHODS: PWH were recruited …

Post-Hemorrhagic Hydrocephalus Of Prematurity Is Associated With Disruption Of Tight Junctions And Increased Macrophage Activity In The Choroid Plexus, Maria Garcia-Bonilla, Rajiv Swarup, Owen W Limbrick, Habeebah Z Vohra, Ayodamola Otun, Konrad Mckalip, William Bernhardt, Kirill Shumilov, Marie Michenkova, Jayne Crouthamel, Mackenzie Newman, Krikor Dikranian, James P Mcallister Ii, David D Limbrick

2020-Current year OA Pubs

BACKGROUND: Previous studies on intraventricular hemorrhage (IVH), a common and severe complication of preterm birth, and subsequent post-hemorrhagic hydrocephalus (PHH), have predominantly concentrated on the secretory function of the choroid plexus (ChP), with considerably less emphasis on its barrier function. We hypothesized that PHH is associated with immune-related alterations in the junction biology of ChP. METHODS: We examined differences in tight junctions and macrophages using a neonatal mouse model of PHH (n = 40) and in vitro ChP explants (n = 22), as well as human post-mortem samples (n = 6). To test our hypothesis, we employed histology, immunofluorescence, magnetic …

Mary Holly Smith

African American Funeral Programs

No abstract provided.

A Pathogenic Tau Mutation Drives Autophagy-Lysosome Dysfunction That Limits Tau Degradation In A Model Of Frontotemporal Dementia, Farzaneh S Mirfakhar, Jacob A Marsh, Chihiro Sato, Kylie J Schache, Miguel A Minaya, Roland E Dolle, Stephen C Pak, Gary A Silverman, David H Perlmutter, Shannon L Macauley, Celeste M Karch

2020-Current year OA Pubs

Tau accumulates in a group of neurodegenerative diseases known as tauopathies. A prevailing hypothesis has been that Tau degradation is impaired due to an age-related imbalance in the autophagy-lysosome pathway, but whether these defects are a cause or consequence of Tau accumulation remains unclear. Here we show that a disease-causing mutation in the MAPT gene, which encodes Tau, p.R406W, is sufficient to disrupt multiple steps of the autophagy-lysosome pathway in human neurons. Using Airyscan super-resolution imaging, we find that mutant Tau neurons accumulate Tau and phosphorylated Tau in dysfunctional lysosomes, exhibit reduced lysosome motility, impaired fusion of autophagosomes and lysosomes, …

Developing A Novel Index For Neighborhood Social Determinants Of Cardiovascular Diseases In The Cardia Study, Tao Gao, Yinan Zheng, Brian T Joyce, Lei Liu, Lili Liu, Catarina Kiefe, Sarah Forrester, Penny Gordon-Larsen, Chunyu Liu, Donald Lloyd-Jones, Kai Zhang, Lifang Hou

2020-Current year OA Pubs

Neighborhood social determinants of health have been shown to influence cardiovascular risk and the development of cardiovascular disease, but few studies have been done about early-life exposure as well as the combined effect of multiple neighborhood social determinants of health measures. Each 1-standard-deviation increase in the neighborhood social determinants of health index is associated with increased risk of coronary artery calcification at the year 7, year 15, and year 20 visits (Odds Ratios range from 1.15 to 1.17). The area under the Receiver Operating Characteristics curve ranges between 0.718 (year 7) and 0.719 (year 20). Compared to White participants, Black …

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LAII Events

Come practice your Portuguese language skills and enjoy Brazilian food and culture with friends!

Amy Eagan Departs Lindenwood For Head Coaching Role With The New Mexico, Truman Griessel

Lindenlink (2012- )

No abstract provided.

On Links Between A Theorem Of Schoenberg, Rohlin Decompositions Of Measures, The Bochner-Minlos Theorem And The Fock Space, Daniel Alpay, Paula Cerejeiras, Palle Jorgensen, Uwe Kaehler

Mathematics, Physics, and Computer Science Faculty Articles and Research

The main goal of this paper is to gain new results in stochastics by drawing on, and combining, different areas that are normally not considered to be related. Thus, in this paper we extend the previous class of Gaussian-like functions ML which will allow for future generalized stochastic processes in infinite dimensional analysis. We show that an approach similar to the one by the classical Bochner-Minlos theorem for the white-noise case can be achieved by using Gaussian-like functions belonging to a large family -the ML_r classes (0 < r ≤∞). We show how Schoenberg’s theorem for positive definite functions on a Hilbert space allows to go beyond the classical setting of Bochner-Milnos theorem. Furthermore, we show that the application of the Rohlin’s disintegration theorem allows for a decomposition of the associated probability measures , see Theorems 3.2 and 4.3. We end this paper with several important examples of functions in these classes ML_r and provide some interesting counterexamples, e.g. Theorem 7.4, to get a …

Quantum Indiscernibility And Perspectivalism, Emily Adlam

Mathematics, Physics, and Computer Science Faculty Articles and Research

It has often been suggested that similar quantum particles may be a counterexample to the principle of the Identity of Indiscernibles. In this article, I discuss the status of indiscernibility in a perspectival approach to quantum mechanics. I argue that adopting an internal physical perspective can have the effect of making entities discernible even if they are not discernible relative to external reference frames, and thus perspectivalism offers a new way to understand the physical meaning of weak discernibility. I discuss whether this approach is circular, and I consider whether the reference frames involved are physically meaningful. I conclude that …