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Influence Of Heuristic Techniques And Biases In Investment Decision-Making: A Conceptual Analysis And Directions For Future Research, Mensah Morris Ayaa, Williams Kwasi Peprah, Maxwell Okpoti Mensah, Adu Bismark Owusu-Sekyere, Bamfo Daniel May 2022

Influence Of Heuristic Techniques And Biases In Investment Decision-Making: A Conceptual Analysis And Directions For Future Research, Mensah Morris Ayaa, Williams Kwasi Peprah, Maxwell Okpoti Mensah, Adu Bismark Owusu-Sekyere, Bamfo Daniel

Faculty Publications

Purpose: The primary purpose of the study was to examine the roles of heuristic techniques and cognitive biases in Investment decision making and suggest directions for future research. Design/Methodology/Approach: The study adopted the literature review method to solicit an understanding of the heuristics and biases central to behavioural finance and influence investment decision-making. Findings: The paper provides conceptual insights into the influence of heuristic techniques and cognitive biases in investment decision-making. Results from the conceptual analysis show that in recent times, investors in their bid to minimise losses and maximize gains employ a range of heuristics which often lead to …


Performance Projection Of A High-Temperature Co2 Transport Membrane Reactor For Combined Co2 Capture And Methane-To-Ethylene Conversion, Xin Li, Kevin Huang, Noah Van Dam, Xinfang Jin May 2022

Performance Projection Of A High-Temperature Co2 Transport Membrane Reactor For Combined Co2 Capture And Methane-To-Ethylene Conversion, Xin Li, Kevin Huang, Noah Van Dam, Xinfang Jin

Faculty Publications

Direct conversion of methane into ethylene through the oxidative coupling of methane (OCM) is a technically important reaction. However, conventional co-fed fixed-bed OCM reactors still face serious challenges in conversion and selectivity. In this paper, we apply a finite element model to simulate OCM reaction in a plug-flow CO2 /O2 transport membrane (CTM) reactor with a directly captured CO2 and O2 mixture as a soft oxidizer. The CTM is made of three phases: molten carbonate, 20% Sm-doped CeO2 , and LiNiO2 . The membrane parameters are first validated by CO2 /O2 flux …


Factors Affecting Emergency Department Mental Health Visits, Logan Daul May 2022

Factors Affecting Emergency Department Mental Health Visits, Logan Daul

Honors Thesis

Research has shown that current quantities of emergency department visits for mental health and substance use are increasing at a startling rate. These increases are acknowledged in quantitative studies and some important information can be gathered from qualitative studies however determining specific causes for these emergent visits are difficult. The purpose of this study is to derive findings from statistical analyses focusing on quantities of emergency department visits for mental health and substance use disorders. Comparisons will be drawn at the state level between the per capita quantity of emergency department visits and poverty rate, climate, psychiatric healthcare infrastructure, urban …


Chirality In Light–Matter Interaction, Andrew Lininger, Madhav Goel, Michael Hinczewski, Giuseppe Strangi May 2022

Chirality In Light–Matter Interaction, Andrew Lininger, Madhav Goel, Michael Hinczewski, Giuseppe Strangi

Faculty Scholarship

The scientific effort to control the interaction between light and matter has grown exponentially in the last 2 decades. This growth has been aided by the development of scientific and technological tools enabling the manipulation of light at deeply sub-wavelength scales, unlocking a large variety of novel phenomena spanning traditionally distant research areas. Here, the role of chirality in light–matter interactions is reviewed by providing a broad overview of its properties, materials, and applications. A perspective on future developments is highlighted, including the growing role of machine learning in designing advanced chiroptical materials to enhance and control light–matter interactions across …


Adoration Above Objectification: The Promotion Of Other In Black, Mexican And Arabic Love Poetry, Joycelynn L. Baker May 2022

Adoration Above Objectification: The Promotion Of Other In Black, Mexican And Arabic Love Poetry, Joycelynn L. Baker

Honors Projects

This paper analyzes the philosophical fundamentals of sexual objectification and presents opposing literature, written in the 20th century, by Black, Mexican and Arabic male poets in contrast. In vigorous patriarchal environments that provide more opportunities to practice sexual objectification, the poets reframe male metaphysical perception and behavior in romantic or sexual contexts by promoting the autonomy and agency of women above themselves, and displaying their enjoyment of that situation. This paper will discuss how Western metaphysical philosophy impacts self-perception and belief in contemporary romantic contexts.


Heterogeneity Of Gene Expression In Peanut-Allergic Cells May Be Related To Differing Cell Subpopulations, Sophia R. Tekorius May 2022

Heterogeneity Of Gene Expression In Peanut-Allergic Cells May Be Related To Differing Cell Subpopulations, Sophia R. Tekorius

Honors Projects

Peanut allergies can have severe and life-threatening complications. By understanding the biology of individuals struggling with this disease, better treatments can be developed. This project explores the possibility of two phenotypically distinct cell types within CD154+ cell types in patients with peanut allergy. Previous studies show that there is a Th2 cell subpopulation associated with allergies, and within effector CD4+ memory populations two distinct phenotypes have been found. This project expands upon this research at the genetic level and through bioinformatic analyses, including the production of heatmaps, the project has found evidence for differing gene expression in two cell subpopulations. …


Differentiating Dolphin Dialects, Rebecca Irelan May 2022

Differentiating Dolphin Dialects, Rebecca Irelan

UNH Today Archive

No abstract provided.


The Development Of A Global Shoreland Information Database May Help Determine The Appropriate Bacteria And Nutrient Technology Needed To Remediate Oil Contaminated Shorelands, Tiffany Ann Veeder May 2022

The Development Of A Global Shoreland Information Database May Help Determine The Appropriate Bacteria And Nutrient Technology Needed To Remediate Oil Contaminated Shorelands, Tiffany Ann Veeder

Honors Projects

The use of oil and its derivative products is well known world-wide. The benefits of oil are many and its products, for example, range from gasoline used in our automobiles to its use in plastics, building products, and medical supplies. Oil spill hazards associated with oil extraction, production, and transportation can have devastating impacts on the environment and local economies. When oil spills happen in the water, for instance, major shorelands are placed at risk of significant harm. As oil contaminates shorelands, the impacts can range from killing sea creatures and seabirds to destroying entire ecosystems. To help mitigate the …


Evaluating Psychiatric Nursing Competencies Applied To Emergency Settings: A Pilot Role Delineation Study, Joanna J. Mello May 2022

Evaluating Psychiatric Nursing Competencies Applied To Emergency Settings: A Pilot Role Delineation Study, Joanna J. Mello

Theses

Aims: 1) To examine emergency department (ED) nurses' reports of a) frequency b) importance and c) self-efficacy related to the application of recommended psychiatric nursing competencies in three domains (i.e., assessment, tasks, knowledge).

2) To test the extent to which frequency and importance independently predict ED nurses' self-efficacy related to the application of the competencies in their daily work.


Institute Of Child Nutrition Joins With Fare To Address Food Allergies, Staff Report May 2022

Institute Of Child Nutrition Joins With Fare To Address Food Allergies, Staff Report

University of Mississippi News

Partnership promises to strengthen resources and training for child nutrition programs


Eight Tips For The Implementation Of The First Licenced Peanut Allergy Oral Immunotherapy Into Clinical Practice., Jay M. Portnoy, Christina E. Ciaccio, Janet Beausoleil, George Du Toit, Stanley Fineman, Stephen A. Tilles, June Zhang, Claire Lawrence, Mohamed Yassine, S Shahzad Mustafa May 2022

Eight Tips For The Implementation Of The First Licenced Peanut Allergy Oral Immunotherapy Into Clinical Practice., Jay M. Portnoy, Christina E. Ciaccio, Janet Beausoleil, George Du Toit, Stanley Fineman, Stephen A. Tilles, June Zhang, Claire Lawrence, Mohamed Yassine, S Shahzad Mustafa

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Shared learnings from the early use of novel therapies can aid in their optimization. The recent introduction of peanut oral immunotherapy (peanut OIT; Palforzia [Peanut (Arachis hypogaea) Allergen Powder-dnfp]) for peanut allergy addresses a significant unmet need but also highlights the requirement for consideration of several factors by both prescribers and patients.

OBJECTIVE: To provide guidance for prescribers of licenced peanut OIT to facilitate treatment delivery and improve outcomes.

METHODS: Clinicians with experience of licenced peanut OIT (United States n = 6, United Kingdom n = 1) participated in a series of interviews and group discussions designed to elicit …


The Scientific Method As A Scaffold To Enhance Communication Skills In Chemistry, Thomas D. Montgomery, Joanne Rae Buchbinder, Ellen S. Gawalt, Robbie J. Iuliucci, Andrew S. Koch, Evangelia Kotsikorou, Patrick E. Lackey, Min Soo Lim, Jeffrey Joseph Rohde, Alexander J. Rupprecht May 2022

The Scientific Method As A Scaffold To Enhance Communication Skills In Chemistry, Thomas D. Montgomery, Joanne Rae Buchbinder, Ellen S. Gawalt, Robbie J. Iuliucci, Andrew S. Koch, Evangelia Kotsikorou, Patrick E. Lackey, Min Soo Lim, Jeffrey Joseph Rohde, Alexander J. Rupprecht

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Scientific success in the field of chemistry depends upon the mastery of a wide range of soft skills, most notably scientific writing and speaking. However, training for scientific communication is typically limited at the undergraduate level, where students struggle to express themselves in a clear and logical manner. The underlying issue is deeper than basic technical skills; rather, it is a problem of students’ unawareness of a fundamental and strategic framework for writing and speaking with a purpose. The methodology has been implemented for individual mentorship and in our regional summer research program to deliver a blueprint of thought and …


Modern Monetary Theory: Merits, Critiques, And Contemporary Implications, Rebecca Singleton, Thomas Herndon May 2022

Modern Monetary Theory: Merits, Critiques, And Contemporary Implications, Rebecca Singleton, Thomas Herndon

Honors Thesis

The study of macroeconomics is a diverse field, with conflicting opinions and numerous camps of thought. The election of 2016 brought this to the public attention, as the appointment of Stephanie Kelton as Senator Bernie Sanders’s campaign economic advisor brought Dr. Kelton’s heterodox school of macroeconomic policy to the attention of mass media. In particular, Modern Monetary Theory became a public discussion, particularly in the wake of stimulus spending during the COVID-19 pandemic. Modern Monetary Theory (MMT), a heterodox macroeconomic theory most discussed in far-left and post-Keynesian academic circles, has faced backlash from a centrist mass media. I investigate the …


Engaging The Adult College Student: A Case Study On Improving Nontraditional Students’ Persistence, Conzolo L. Migliozzi May 2022

Engaging The Adult College Student: A Case Study On Improving Nontraditional Students’ Persistence, Conzolo L. Migliozzi

Instructional Design Capstones Collection

Nontraditional students, defined as those age 25 and older, had a first-year persistence rate of just 46.8% in 2019 (National Student Clearinghouse, 2021). The Education Fund, a large non-profit that provides training and tuition assistance to healthcare workers, is acutely aware of this problem as its membership is made up almost entirely of nontraditional learners. The Education Fund has many college readiness programs, and in an effort to improve upon their outcomes, requested this study on student persistence. Research on nontraditional student persistence was conducted and key Education Fund staff were interviewed as part of this project. While the literature …


Library Anxiety Among Undergraduate Students: A Case Study Of Faculty Of Management Science, University Of Peshawar, Muhammad Ismail, Abid Hussain, Sana Gul, Imran Ahmad May 2022

Library Anxiety Among Undergraduate Students: A Case Study Of Faculty Of Management Science, University Of Peshawar, Muhammad Ismail, Abid Hussain, Sana Gul, Imran Ahmad

Library Philosophy and Practice (e-journal)

Library anxiety is a psychological barrier to the academic performance of university students. This study was conducted among undergraduate students at the faculty of management sciences, the University of Peshawar to examine the factors which predict library anxiety. Library anxiety is a psychological barrier to academic success among college students. This study of 843 undergraduate team was administered by hand to all the sample size among university students in order to examine factors that predict library anxiety, a sample size of 262 was drawn 244 questionnaires was collected with a response rate of 93.12% based on Krejcie and Morgan’s (1970) …


Board Of Directors Meeting Minutes (May 9, 2022), Dmacc May 2022

Board Of Directors Meeting Minutes (May 9, 2022), Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on May 9, 2022.


Global Collision-Risk Hotspots Of Marine Traffic And The World’S Largest Fish, The Whale Shark, Freya C. Womersley, Nicolas E. Humphries, Nuno Queiroz, Marisa Vedor, Ivo Da Costa, Miguel Furtado, John P. Tyminski, Katya Abrantes, Gonzalo Araujo, Steffen S. Bach, Adam Barnett, Michael L. Berumen, Sandra Bessudo Lion, Camrin D. Braun, Elizabeth Clingham, Jesse E. M. Cochran, Rafael De La Parra, Stella Diamant, Alistair D. M. Dove, Christine L. Dudgeon, Mark V. Erdmann, Eduardo Espinoza, Richard Fitzpatrick, Jaime González Cano, Jonathan R. Green, Hector M. Guzman, Royale Hardenstine, Abdi Hasan, Fábio H. V. Hazin, Alex R. Hearn, Robert E. Hueter, Mohammed Y. Jaidah, Jessica Labaja, Felipe Ladino, Bruno C. L. Macena, John J. Morris Jr., Bradley M. Norman, Cesar Peñaherrera-Palma, Simon J. Pierce, Lina Maria Quintero, Dení Ramírez-Macías, Samantha D. Reynolds, Anthony J. Richardson, David P. Robinson, Christoph A. Rohner, David R. L. Rowat, Marcus Sheaves, Mahmood Shivji, Abraham B. Sianipar, Gregory B. Skomal, German Soler, Ismail Syakurachman, Simon R. Thorrold, D. Harry Webb, Bradley M. Wetherbee, Timothy D. White, Tyler Clavelle, David A. Kroodsma, Michele Thums, Luciana C. Ferreira, Mark G. Meekan, Lucy M. Arrowsmith, Emily K. Lester, Megan M. Meyers, Lauren R. Peel, Ana M. M. Sequeira, Victor M. Eguiluz, Carlos M. Duarte, David W. Sims May 2022

Global Collision-Risk Hotspots Of Marine Traffic And The World’S Largest Fish, The Whale Shark, Freya C. Womersley, Nicolas E. Humphries, Nuno Queiroz, Marisa Vedor, Ivo Da Costa, Miguel Furtado, John P. Tyminski, Katya Abrantes, Gonzalo Araujo, Steffen S. Bach, Adam Barnett, Michael L. Berumen, Sandra Bessudo Lion, Camrin D. Braun, Elizabeth Clingham, Jesse E. M. Cochran, Rafael De La Parra, Stella Diamant, Alistair D. M. Dove, Christine L. Dudgeon, Mark V. Erdmann, Eduardo Espinoza, Richard Fitzpatrick, Jaime González Cano, Jonathan R. Green, Hector M. Guzman, Royale Hardenstine, Abdi Hasan, Fábio H. V. Hazin, Alex R. Hearn, Robert E. Hueter, Mohammed Y. Jaidah, Jessica Labaja, Felipe Ladino, Bruno C. L. Macena, John J. Morris Jr., Bradley M. Norman, Cesar Peñaherrera-Palma, Simon J. Pierce, Lina Maria Quintero, Dení Ramírez-Macías, Samantha D. Reynolds, Anthony J. Richardson, David P. Robinson, Christoph A. Rohner, David R. L. Rowat, Marcus Sheaves, Mahmood Shivji, Abraham B. Sianipar, Gregory B. Skomal, German Soler, Ismail Syakurachman, Simon R. Thorrold, D. Harry Webb, Bradley M. Wetherbee, Timothy D. White, Tyler Clavelle, David A. Kroodsma, Michele Thums, Luciana C. Ferreira, Mark G. Meekan, Lucy M. Arrowsmith, Emily K. Lester, Megan M. Meyers, Lauren R. Peel, Ana M. M. Sequeira, Victor M. Eguiluz, Carlos M. Duarte, David W. Sims

Biology Faculty Articles

Marine traffic is increasing globally yet collisions with endangered megafauna such as whales, sea turtles, and planktivorous sharks go largely undetected or unreported. Collisions leading to mortality can have population-level consequences for endangered species. Hence, identifying simultaneous space use of megafauna and shipping throughout ranges may reveal as-yet-unknown spatial targets requiring conservation. However, global studies tracking megafauna and shipping occurrences are lacking. Here we combine satellite-tracked movements of the whale shark, Rhincodon typus, and vessel activity to show that 92% of sharks’ horizontal space use and nearly 50% of vertical space use overlap with persistent large vessel (>300 …


University Of Northern Iowa Faculty Senate Special Meeting Minutes, May 9, 2022, University Of Northern Iowa, Faculty Senate May 2022

University Of Northern Iowa Faculty Senate Special Meeting Minutes, May 9, 2022, University Of Northern Iowa, Faculty Senate

Documents - Faculty Senate

Meeting minutes from the Faculty Senate of the University of Northern Iowa.


Comparison Of Hemodynamic Responses Between Conventional And Virtual Reality Therapies In Patients With Heart Failure Admitted To An Emergency Room, Angélica Bologna Raposo, Alice Haniuda Moliterno, João Pedro Lucas Neves Silva, Rafael Varago Favri, Ana Paula Coelho Figueira Freire, Francis Lopes Pacagnelli May 2022

Comparison Of Hemodynamic Responses Between Conventional And Virtual Reality Therapies In Patients With Heart Failure Admitted To An Emergency Room, Angélica Bologna Raposo, Alice Haniuda Moliterno, João Pedro Lucas Neves Silva, Rafael Varago Favri, Ana Paula Coelho Figueira Freire, Francis Lopes Pacagnelli

All Faculty Scholarship for the College of Education and Professional Studies

This study aimed to evaluate and to compare the acute response, due to semi-immersive virtual reality (VR) and conventional therapies (CT), of hemodynamic parameters in hospitalized individuals admitted to an emergency unity for heart failure (HF). This is a viability study with 11 individuals subjected to sessions with and without VR. At CT, stretching, active or active-assisted exercises, and fractional inspiration were performed. In VR therapy (VRT), VR box glasses were used to promote VR relaxation associated with CT. The hemodynamic parameters evaluated were heart rate, systolic and diastolic blood pressure, oxygen saturation, and double product. To analyze them, Student’s …


Russia's Agenda For Ukraine: An Examination Of Putin's Media Propaganda Narratives, Gillian Grace Littleton May 2022

Russia's Agenda For Ukraine: An Examination Of Putin's Media Propaganda Narratives, Gillian Grace Littleton

Honors Theses

This thesis explores Russian discourse about Ukraine as reflected in Russian popular media since 2014’s Euromaidan Revolution. The thesis provides an overview of Russia’s historic denial of Ukrainian statehood and it argues: Russian historians and politicians have seen Ukraine as a “little-brother” nation to Russia, with a shared Slavic heritage, and that any attempts by Ukrainians to separate themselves from Russia are Western influence movements. The thesis examines three types of mass media in order to demonstrate the interaction between history, politics and popular culture. Chapter 1 explores the public speeches of key Russian political figures including Vladimir Putin himself, …


Understanding The Transport And Chemistry Of Indoor Air During Wildfire Smoke Events With Elliott Gall, Elliott T. Gall May 2022

Understanding The Transport And Chemistry Of Indoor Air During Wildfire Smoke Events With Elliott Gall, Elliott T. Gall

PDXPLORES Podcast

Dr. Elliott Gall, Associate Professor in the Mechanical and Materials Engineering Department at Portland State University, studies indoor air quality in order to better understand how to improve building designs to promote health.

Wildfires are increasing in frequency and intensity. So, too, are wildfire smoke events. Smoke from wildfires pose serious health risks. That is why the Environmental Protection Agency recommends individuals remain indoors during smoke events.

In this episode, Professor Gall discusses the importance of understanding the chemistry of wildfire smoke indoors and how smoke is transported into buildings.

Click on the "Download" button to access the audio transcript.


5.9.22, Amber Brost May 2022

5.9.22, Amber Brost

ASWC Agendas

No abstract provided.


Art 399 Portfolio, Olivia Swaidner May 2022

Art 399 Portfolio, Olivia Swaidner

Professional Practices (ART 399)

Olivia Swaidner

Artist Statement

Most of my inspiration for my art comes from one of two things: Impression of nature or personal struggles. Biology isn’t something that particularly shows up in my work in an obvious way, but my fascination and impression with science and nature inspires what I create. The mediums that I typically work in the most are painting and photography. My more recent series of film photographs featured multiple images of twisted, exposed roots on the bank of a creek bed. The intention of many of my photographs is to show hidden aspects of nature that I …


The Rise Of Xr Storytelling And The Contribution Of Consumer Accessibility, Cost Efficiency, & Intrinsic Value To Feasibility, Sarah Moffatt May 2022

The Rise Of Xr Storytelling And The Contribution Of Consumer Accessibility, Cost Efficiency, & Intrinsic Value To Feasibility, Sarah Moffatt

Book Publishing Final Research Papers

This research assesses the current state of XR (extended reality) publishing and its feasibility within an exceptionally virtual landscape. Feasibility is measured upon the challenges and opportunities posed by accessibility, cost efficiency, demand, and intrinsic value.

Through market analysis of past and ongoing XR storytelling projects, as well as qualitative methods which include industry interviews and public surveys, it has been found that publishers would do well to first adopt augmented reality storytelling methods before venturing further into virtual reality storytelling. Because augmented reality is generally more accessible and cost efficient, its adoption contributes to increased …


Cutting-Edge Imaging Of Cardiac Metastases From Neuroendocrine Tumors: Lesson From A Case Series, Soraya El Ghannudi, Eric Ouvrard, Nidaa Mikail, Benjamin Leroy Freschini, Thomas H Schindler, Alessio Imperiale May 2022

Cutting-Edge Imaging Of Cardiac Metastases From Neuroendocrine Tumors: Lesson From A Case Series, Soraya El Ghannudi, Eric Ouvrard, Nidaa Mikail, Benjamin Leroy Freschini, Thomas H Schindler, Alessio Imperiale

Open Access Publications

With the increasing availability of high-performance medical imaging for the management of patients with neuroendocrine tumors (NETs), a progressive growth of asymptomatic and incidentally detected cardiac metastases (CMs) has been observed in the recent years. In clinical practice, CMs of NENs are often incidentally detected by whole-body


Fluoxetine Exposure Throughout Neurodevelopment Differentially Influences Basilar Dendritic Morphology In The Motor And Prefrontal Cortices, Susan E Maloney, Dora R Tabachnick, Christine Jakes, Selma Avdagic, Amy L Bauernfeind, Joseph D Dougherty May 2022

Fluoxetine Exposure Throughout Neurodevelopment Differentially Influences Basilar Dendritic Morphology In The Motor And Prefrontal Cortices, Susan E Maloney, Dora R Tabachnick, Christine Jakes, Selma Avdagic, Amy L Bauernfeind, Joseph D Dougherty

Open Access Publications

The significance of serotonin (5HT) in mental health is underscored by the serotonergic action of many classes of psychiatric medication. 5HT is known to have a significant role in neurodevelopment, thus 5HT disruption during development may have a long term impact on brain structure and circuits. We previously generated a model of 5HT alteration throughout neurodevelopment by maternal administration of the selective serotonin reuptake inhibitor fluoxetine. We found resulting social behavior alterations in the offspring during both postnatal and adult ages. Previous work by others has indicated that early 5HT disruption influences neuronal morphology. Therefore, in the current study we …


Benefits Of Newborn Screening And Hematopoietic Cell Transplant In Infantile Krabbe Disease, Kristin M Page, Margie A Ream, Hemalatha G Rangarajan, Rafael Galindo, Ali Y Mian, Mai-Lan Ho, James Provenzale, Kathryn E Gustafson, Jennifer Rubin, Shalini Shenoy, Joanne Kurtzberg May 2022

Benefits Of Newborn Screening And Hematopoietic Cell Transplant In Infantile Krabbe Disease, Kristin M Page, Margie A Ream, Hemalatha G Rangarajan, Rafael Galindo, Ali Y Mian, Mai-Lan Ho, James Provenzale, Kathryn E Gustafson, Jennifer Rubin, Shalini Shenoy, Joanne Kurtzberg

Open Access Publications

Infantile Krabbe disease (IKD) can be treated with hematopoietic cell transplantation (HCT) if done during the first weeks of life before symptoms develop. To facilitate this, newborn screening (NBS) has been instituted in 8 US states. An application to add IKD to the recommended NBS panel is currently under review. In this report, the outcomes of newborns with IKD diagnosed through NBS and treated with HCT are presented. The unique challenges associated with NBS for this disease are discussed, including opportunities for earlier diagnosis and streamlining treatment referrals. This is a retrospective review of six infants with IKD detected by …


Caveolin-1 Temporal Modulation Enhances Antibody Drug Efficacy In Heterogeneous Gastric Cancer, Patrícia M R Pereira, Komal Mandleywala, Sébastien Monette, Melissa Lumish, Kathryn M Tully, Sandeep Surendra Panikar, Mike Cornejo, Audrey Mauguen, Ashwin Ragupathi, Nai C Keltee, Marissa Mattar, Yelena Y Janjigian, Jason S Lewis May 2022

Caveolin-1 Temporal Modulation Enhances Antibody Drug Efficacy In Heterogeneous Gastric Cancer, Patrícia M R Pereira, Komal Mandleywala, Sébastien Monette, Melissa Lumish, Kathryn M Tully, Sandeep Surendra Panikar, Mike Cornejo, Audrey Mauguen, Ashwin Ragupathi, Nai C Keltee, Marissa Mattar, Yelena Y Janjigian, Jason S Lewis

Open Access Publications

Resistance mechanisms and heterogeneity in HER2-positive gastric cancers (GC) limit Trastuzumab benefit in 32% of patients, and other targeted therapies have failed in clinical trials. Using patient samples, patient-derived xenografts (PDXs), partially humanized biological models, and HER2-targeted imaging technologies we demonstrate the role of caveolin-1 (CAV1) as a complementary biomarker in GC selection for Trastuzumab therapy. In retrospective analyses of samples from patients enrolled on Trastuzumab trials, the CAV1-high profile associates with low membrane HER2 density and low patient survival. We show a negative correlation between CAV1 tumoral protein levels - a major protein of cholesterol-rich membrane domains - and …


The Impact Of Targeted Regulation Of Abortion Providers Laws On Abortions And Births, Grace E. Arnold May 2022

The Impact Of Targeted Regulation Of Abortion Providers Laws On Abortions And Births, Grace E. Arnold

Economics Faculty Publications and Presentations

This paper analyzes the impact of supply-side abortion restrictions on aggregate abortion and birth rates in the USA. Specifically, I exploit state and time variation in the implementation of the first targeted regulation of abortion provider (TRAP) law in a state to identify the effects of the laws. I find that TRAP laws are associated with a reduction in the abortion rate of approximately 5% the year the first law is implemented, and an average reduction of 11–14% in subsequent years. There is also evidence that TRAP laws increased birth rates by 2–3%, which accounts for approximately 80–100% of the …


Effectiveness Of Short-Term Heat Acclimation On Intermittent Sprint Performance In The Heat With Moderately Trained Males, Andrew T. Garrett, Matt Birkett, Damien O. Gleadall-Siddall, Rachel Burke, James Bray, Fiona Nation May 2022

Effectiveness Of Short-Term Heat Acclimation On Intermittent Sprint Performance In The Heat With Moderately Trained Males, Andrew T. Garrett, Matt Birkett, Damien O. Gleadall-Siddall, Rachel Burke, James Bray, Fiona Nation

Journal of Human Performance in Extreme Environments

Purpose: Effectiveness of short-term heat acclimation (STHA), over 5-days (permissive dehydration), on intermittent heat stress test (HST) with males. Methods: Ten, moderately-trained, males (mean [SD]; age 25.6 [8.9] y; stature 180.7 [5.6] cm; body mass 83.2 [10.8] kg; and 45.3 [6.5] mL.kg-1.min-1) participated. The HST was 9 x 5min (45-min) of intermittent exercise based on professional soccer players. One week apart, HST1 vs HST (11.0°C; 50%RH), as a reliability trial and HST3 in 31.0°C; 50%RH were completed. Then 90 min dehydration, STHA (no fluid intake), for 5 consecutive days (39.5oC; 60%RH), using …