Digital Commons Network^™

Transitioning From Traditional In-Person Studio-Based Education Of Apparel Design Courses To Online Education During The Covid-19 Pandemic, Divya Desai

LSU Doctoral Dissertations

Due to the COVID-19 pandemic and subsequent lockdowns many post-secondary educational institutions all-around the world, including the USA, were forced to transition their teaching methods from a traditional in-person to an online teaching format starting in the spring of 2020. This research however is focused on the transitioning of university-level studio-based Apparel Design (AD) courses to an online teaching format during the spring and fall 2020 semesters. Teaching AD courses that are studio-based and that particularly require hands-on skills like hand rendering, draping, sewing, or pattern drafting, are challenging to be taught online as they require in person step-by-step guidance …

X-Ray Observation Of The Roche-Lobe-Filling White Dwarf Plus Hot Subdwarf System Ztf J213056.71+442046.5, S. Mereghetti, N. La Palombara, T. Kupfer, T. R. Marsh, C. M. Copperwheat, K. Deshmukh, P. Esposito, T. Maccarone, F. Pintore, Liliana Rivera Sandoval

Physics & Astronomy Faculty Publications

ZTF J213056.71+442046.5 is the prototype of a small class of recently discovered compact binaries composed of a white dwarf and a hot subdwarf that fills its Roche lobe. Its orbital period of only 39 minutes is the shortest known for the objects in this class. Evidence for a high orbital inclination (i = 86°) and for the presence of an accretion disk has been inferred from a detailed modeling of its optical photometric and spectroscopic data. We report the results of an XMM-Newton observation carried out on 2021 January 7. ZTF J213056.71+442046.5 was clearly detected by the Optical Monitor, …

Human M1 Macrophages Express Unique Innate Immune Response Genes After Mycobacterial Infection To Defend Against Tuberculosis, Arshad Khan, Kangling Zhang, Vipul K. Singh, Abhishek Mishra, Priyanka Kachroo, Tian Bing, Jong Hak Won, Eder Ledezma-Campos, Genesis P. Aguillón-Durán, Blanca I. Restrepo

School of Medicine Publications

Mycobacterium tuberculosis (Mtb) is responsible for approximately 1.5 million deaths each year. Though 10% of patients develop tuberculosis (TB) after infection, 90% of these infections are latent. Further, mice are nearly uniformly susceptible to Mtb but their M1-polarized macrophages (M1-MΦs) can inhibit Mtb in vitro, suggesting that M1-MΦs may be able to regulate anti-TB immunity. We sought to determine whether human MΦ heterogeneity contributes to TB immunity. Here we show that IFN-γ-programmed M1-MΦs degrade Mtb through increased expression of innate immunity regulatory genes (Inregs). In contrast, IL-4-programmed M2-polarized MΦs (M2-MΦs) are permissive for Mtb proliferation and exhibit reduced …

A Novel Correction For The Adjusted Box-Pierce Test, Sidy Danioko, Jianwei Zheng, Kyle Anderson, Alexander Barrett, Cyril S. Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

The classical Box-Pierce and Ljung-Box tests for auto-correlation of residuals possess severe deviations from nominal type I error rates. Previous studies have attempted to address this issue by either revising existing tests or designing new techniques. The Adjusted Box-Pierce achieves the best results with respect to attaining type I error rates closer to nominal values. This research paper proposes a further correction to the adjusted Box-Pierce test that possesses near perfect type I error rates. The approach is based on an inflation of the rejection region for all sample sizes and lags calculated via a linear model applied to simulated …

“That’S What Hospice Is Supposed To Do”: How U.S. Hospice Care Staff Bridge Philosophy And Institutions, Morgan Alexa Leff

Senior Honors Papers / Undergraduate Theses

Hospice founder Cicely Saunders wrote that “the dignity and worth of each individual patient [are] central to Hospice philosophy—an idea closely tied to anthropological personhood (Saunders and Clark 2002). As dying in hospice becomes an increasing reality of life in the United States, we must grapple with how the ideals, costs, and challenges of hospice care play out in the healthcare system. The institutional structures meant to ensure a ‘good death’ (while protecting the interests of the state) can fracture care of the dying. As hospice staff work within and around these structures, they build meaning in care strategies that …

Platelets Increase The Expression Of Pd-L1 In Ovarian Cancer, Min Soon Cho, Hani Lee, Ricardo Gonzalez-Delgado, Dan Li, Tomoyuki Sasano, Qing Ma, Anil K Sood, Vahid Afshar-Kharghan

Faculty, Staff and Student Publications

The interactions between platelets and cancer cells activate platelets and enhance tumor growth. Platelets increase proliferation and epithelial-mesenchymal transition in cancer cells, inhibit anoikis, enhance the extravasation of cancer cells, and protect circulating tumor cells against natural killer cells. Here, we have identified another mechanism by which platelets dampen the immune attack on cancer cells. We found that platelets can blunt the antitumor immune response by increasing the expression of inhibitory immune checkpoint (PD-L1) on ovarian cancer cells in vitro and in vivo. Platelets increased PD-L1 in cancer cells via contact-dependent (through NF-κB signaling) and contact-independent (through TFGβR1/Smad signaling) pathways. …

Making National Cancer Institute-Designated Comprehensive Cancer Center Knowledge Accessible To Community Oncologists Via An Online Tumor Board: Longitudinal Observational Study, Maitri Kalra, Elizabeth Henry, Kelly Mccann, Meghan S Karuturi, Jean G Bustamante Alvarez, Robert Wesolowski, Sarah S Mougalian, Gregory Durm, Angel Qin, Caitlin Schonewolf, Meghna Trivedi, Avan J Armaghani, Frederick H Wilson, Wade T Iams, Anita A Turk, Praveen Vikas, Michael Cecchini, Sam Lubner, Priyadarshini Pathak, Kristen Spencer, Vadim S Koshkin, Matthew K Labriola, Catherine H Marshall, Katy E Beckermann, Marina N Sharifi, Anthony C Bejjani, Varsha Hotchandani, Samir Housri, Nadine Housri

Faculty, Staff and Student Publications

Background: Expert knowledge is often shared among multidisciplinary academic teams at tumor boards (TBs) across the country, but these conversations exist in silos and do not reach the wider oncology community.

Objective: Using an oncologist-only question and answer (Q&A) website, we sought to document expert insights from TBs at National Cancer Institute-designated Comprehensive Cancer Centers (NCI-CCCs) to provide educational benefits to the oncology community.

Methods: We designed a process with the NCI-CCCs to document and share discussions from the TBs focused on areas of practice variation on theMednet, an interactive Q&A website of over 13,000 US oncologists. The faculty translated …

Inhibition Of Mitochondrial Complex I Reverses Notch1-Driven Metabolic Reprogramming In T-Cell Acute Lymphoblastic Leukemia, Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan Collins, Renu Pandey, Shraddha Patel, Mathieu Tremblay, Vinitha Mary Kuruvilla, Antonio Cavazos, Mecit Kaplan, Marc O Warmoes, Diogo Troggian Veiga, Ken Furudate, Shanti Rojas-Sutterin, Andre Haman, Yves Gareau, Anne Marinier, Helen Ma, Karine Harutyunyan, May Daher, Luciana Melo Garcia, Gheath Al-Atrash, Sujan Piya, Vivian Ruvolo, Wentao Yang, Sriram Saravanan Shanmugavelandy, Ningping Feng, Jason Gay, Di Du, Jun J Yang, Fieke W Hoff, Marcin Kaminski, Katarzyna Tomczak, R Eric Davis, Daniel Herranz, Adolfo Ferrando, Elias J Jabbour, M Emilia Di Francesco, David T Teachey, Terzah M Horton, Steven Kornblau, Katayoun Rezvani, Guy Sauvageau, Mihai Gagea, Michael Andreeff, Koichi Takahashi, Joseph R Marszalek, Philip L Lorenzi, Jiyang Yu, Stefano Tiziani, Trang Hoang, Marina Konopleva

Faculty, Staff and Student Publications

T-cell acute lymphoblastic leukemia (T-ALL) is commonly driven by activating mutations in NOTCH1 that facilitate glutamine oxidation. Here we identify oxidative phosphorylation (OxPhos) as a critical pathway for leukemia cell survival and demonstrate a direct relationship between NOTCH1, elevated OxPhos gene expression, and acquired chemoresistance in pre-leukemic and leukemic models. Disrupting OxPhos with IACS-010759, an inhibitor of mitochondrial complex I, causes potent growth inhibition through induction of metabolic shut-down and redox imbalance in NOTCH1-mutated and less so in NOTCH1-wt T-ALL cells. Mechanistically, inhibition of OxPhos induces a metabolic reprogramming into glutaminolysis. We show that pharmacological blockade of OxPhos combined with …

Modelling The Daily Electricity Demand Of Electric Vessels In Plymouth, L Ansell

School of Engineering, Computing and Mathematics

No abstract provided.

Editorial: The Dual-Use Dilemma For Biomimicry, Samar Damiati, Rami Mhanna, Shakil A. Awan, Rimantas Kodzius, Bernhard Schuster

School of Engineering, Computing and Mathematics

The biomimetic fabrication of 3D biology models confers design freedom across various applications. Taking inspiration from nature and using nature as a toolbox have helped in the production of effective and versatile tools that are integrated with modern technology principles and, importantly, perform quite similarly to natural living systems. Exploiting nature’s design principles can contribute to the improvement of the understanding and development of creative products in both fundamental research and industrial applications (Dicks, 2016; Orapiriyakul et al., 2018; Damiati, 2020). To address the significant heterogeneity among bio-inspired designs, this research topic collected articles that reflect the progress in the …

Hosts E-Newsletter: Jul 2021

HoSTS e-Newsletter

No abstract provided.

Mathematical Model Of Zika Epidemic In Colombia, Sethupathy Ganesan

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Model Of Immune-Inflammatory Response In Covid-19 Patients, Quiyana M. Murphy

Biology and Medicine Through Mathematics Conference

No abstract provided.

Studying The Effect Of Western Diet On Atherosclerosis Risk Factors, Eric L. Scott, Rebecca Segal, Angela M. Reynolds

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling And Analysis Of Social Contagion In Overweight And Obesity Epidemic, Chathuri Edirisinghe Arachchige

Biology and Medicine Through Mathematics Conference

No abstract provided.

Scale-Free Properties Influence Breathing Rhythmogenesis., Cameron Grover

Biology and Medicine Through Mathematics Conference

No abstract provided.

Cooccurrr - Applying Glcm Analysis Techniques To Non-Image Objects Such As Fitness Landscapes, Steph J. Owen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling The Spread Of Sars-Cov-2 Inside The Human Respiratory Tract: A Parameter Sensitivity Study, Jason Pearson

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling Viral Resistance To Monotherapy With Monoclonal Antibody Treatment For Sars-Cov-2, Tin Phan, Carolin Zitzmann, Alan S. Perelson, Ruy M. Ribeiro, Ruian Ke

Biology and Medicine Through Mathematics Conference

No abstract provided.

Estimating Glutamate Transporter Surface Density In Mouse Hippocampal Astrocytes, Anca R. Radulescu, Annalisa Scimemi

Biology and Medicine Through Mathematics Conference

No abstract provided.

Parameter Estimation Using Nudging On The Logistic Growth Equation, Susan Rogowski

Biology and Medicine Through Mathematics Conference

No abstract provided.

Automated Fitting Of Allosteric Parameters In Receptor Oligomer Models, Spenser Wood

Biology and Medicine Through Mathematics Conference

No abstract provided.

Effect Of Myeloid-Derived Suppressor Cells On Glioblastoma-Immune Dynamics, Hannah Anderson

Biology and Medicine Through Mathematics Conference

No abstract provided.

Approximate Bayesian Computation For Generating 3d Structured Trees To Model The Pulmonary Arterial Network, Megan J. Chambers

Biology and Medicine Through Mathematics Conference

No abstract provided.

Using Immersed Boundary Method To Understand The Dynamics Of Nematocyst Firing, Abdulrahman Alharbi

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Spatially Dependent Model For Photoreceptors In A Healthy Eye, Danielle C. Brager, Anthony Kearsley, Daniel Anderson

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modelling Of Oncolytic Virotherapy As A Cancer Treatment, Maila Hallare, Iordanka Panayotova

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Within-Host Modeling Framework For Sars-Cov-2 Infection To Support Vaccine Strategies, Morgan Rose, Rachel Jennings, Jeffry Schroeter

Biology and Medicine Through Mathematics Conference

No abstract provided.

Osmotic Perturbation Promotes Competition Between Bacteria In Gut, Shaikh Obaidullah

Biology and Medicine Through Mathematics Conference

No abstract provided.

Seasonality And The Dynamics Of Mycobacterium Ulcerans Transmission., Kwame E. Osei Bonsu

Biology and Medicine Through Mathematics Conference

No abstract provided.