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Articles 710611 - 710640 of 5178893
Full-Text Articles in Entire DC Network
Potential For A Pedagogical Level-Up: Teaching First-Year Composition Through Rhetoric Of Gaming, Cayman Beeman
Potential For A Pedagogical Level-Up: Teaching First-Year Composition Through Rhetoric Of Gaming, Cayman Beeman
English (MA) Theses
Instructors of First-Year Composition courses are pursuing new ways to help integrate students into collegiate writing. One approach that has been gaining more widespread use is teaching composition through a popular medium. Inspired by these pedagogical movements, I designed a first-year composition course that approached writing through looking at different rhetorical elements of video games. During the course I encouraged students to enter into an I.R.B. approved study in which I recorded certain elements of their progression, discourse, and understanding regarding composition taught through gaming in an effort to document what was pedagogically successful, and what aspects of the course …
3h-1,2-Dithiole-3-Thione Suppresses Lps-Induced Proinflammatory Responses In Macrophages: Potential Involvement Of Antioxidant Induction, Nf-Κb, And Nrf2, Hong Zhu, An Bui, Arben Santo, Y R. Li
3h-1,2-Dithiole-3-Thione Suppresses Lps-Induced Proinflammatory Responses In Macrophages: Potential Involvement Of Antioxidant Induction, Nf-Κb, And Nrf2, Hong Zhu, An Bui, Arben Santo, Y R. Li
Osteopathic Medicine, Jerry M. Wallace School of
Previously, we reported that 3H-1,2-dithiole-3-thione (D3T), an Nrf2 activator, acted as a potential chemoprotectant against lipopolysaccharide (LPS)-induced mortality in mice. In view of the critical involvement of macrophages in the pathogenesis of LPS-induced endotoxemia, in the present study, we investigated the protective effects of D3T on LPS-induced proinflammatory responses in cultured murine RAW 264.7 macrophage cell line and primary peritoneal macrophages and the potential involvement of antioxidant induction, NF-κB, and Nrf2. We showed that treatment with D3T resulted in increased levels of a series of antioxidants in RAW 264.7 cells in a concentration-dependent manner. These included the reduced form of …
Multiple Cranial Neuropathies As The Initial Presentation Of Primary Ductal Adenocarcinoma Of The Lacrimal Gland, Jane S. Kim, A D. Proia, Jason Liss, Joel Morgenlander, Landon C. Meekins
Multiple Cranial Neuropathies As The Initial Presentation Of Primary Ductal Adenocarcinoma Of The Lacrimal Gland, Jane S. Kim, A D. Proia, Jason Liss, Joel Morgenlander, Landon C. Meekins
Osteopathic Medicine, Jerry M. Wallace School of
Primary ductal adenocarcinoma of the lacrimal gland is a rare, aggressive malignancy that clinically and histologically resembles salivary duct carcinoma. Similar to other malignant epithelial lacrimal gland tumors, ductal adenocarcinoma typically presents with unilateral proptosis, pain, upper eyelid swelling, palpable mass, diplopia, ptosis, and blurred or decreased vision. Rarely, primary malignant epithelial lacrimal gland tumors may first present with multiple cranial neuropathies due to occult spread to the cavernous sinus, as in this case. With such a vast differential diagnosis, a practical yet systematic approach to multiple cranial neuropathies, as guided by clinical history, exam, and neuroimaging, allows for a …
Educating Church Leaders About Moral Injury To Provide Support To Military Veterans In Their Congregations, James R. Taylor
Educating Church Leaders About Moral Injury To Provide Support To Military Veterans In Their Congregations, James R. Taylor
College of Theology and Ministry Dissertations, Projects, & Theses
Scope and Method of Study: This study sought to enhance the awareness and knowledge of pastors and congregational leaders concerning moral injury in military veterans within their congregations. Ideally, this would reduce the leaders’ anxiety and would promote a stronger willingness to be involved in offering support to military veterans in their congregations. This project focused on enhancing the knowledge of pastors. The project tested the understanding of pastors of a local denomination, offered education to enhance their awareness of veterans’ issues (specifically moral injuries), provided insight into Scriptures that offered examples of moral injury, and recommended what could be …
Social Media And Democracy, Seth C. Oranburg
Social Media And Democracy, Seth C. Oranburg
Law Faculty Scholarship
[Excerpt] "Lately, people have been finding giant pet goldfish in lakes across America. You may see these tiny fish swimming in bowls at the county fair, but left alone in a lake or large pond, where they are dropped perhaps by a well-meaning child, they can grow to 20 pounds or more— and destroy ecosystems. The goldfish is a cautionary tale that has been told time and again in different forms, like Pandora’s box."
Recent Developments: Esteppe V. Balt. City Police Dep't., Jeneen Burrell
Recent Developments: Esteppe V. Balt. City Police Dep't., Jeneen Burrell
University of Baltimore Law Forum
No abstract provided.
Protocol For The Impact Trial: Improving Healthcare Outcomes In American Transplant Recipients Using Culturally-Tailored Novel Technology, Claudia M. Rice, Pooja P Singh, Nila S. Judd, Elizabeth Yakes Jimenez, Cindy K. Blair, Amy Washburn, Christine Calvin, Alison Steiber, Yiliang Zhu, Christos Argyropoulos, Mark Unruh, Mary Amanda Dew, Larissa Myaskovsky
Protocol For The Impact Trial: Improving Healthcare Outcomes In American Transplant Recipients Using Culturally-Tailored Novel Technology, Claudia M. Rice, Pooja P Singh, Nila S. Judd, Elizabeth Yakes Jimenez, Cindy K. Blair, Amy Washburn, Christine Calvin, Alison Steiber, Yiliang Zhu, Christos Argyropoulos, Mark Unruh, Mary Amanda Dew, Larissa Myaskovsky
Pediatrics Research and Scholarship
Kidney transplant (KT) recipients face post-transplant health issues. Immunosuppressive agents can cause hyperlipidemia, hypertension, post-transplant diabetes, and glomerulopathy. Post-transplant weight gain and decreased activity are associated with poor quality of life, sleep, and cardiometabolic outcomes. This study will test the feasibility and acceptability of a culturally tailored diet and exercise intervention for KT patients delivered immediately post-transplant using novel technology. A registered dietitian nutritionist (RDN) and physical rehabilitation therapist will examine participants' cultural background, preferences, and health-related obstacles (with consultation from the transplant team) to create an individualized exercise and meal plan. The RDN will provide medical nutrition therapy via …
The Sea Also Rises, Humboldt County Civil Grand Jury
The Sea Also Rises, Humboldt County Civil Grand Jury
Local Reports and Publications
The public interest in SLR inspired the Humboldt County Civil Grand Jury to investigate why SLR is happening, how damaging its effects will be, and what must be done to adapt to it.
In September 2022, the conclusion of a study conducted by the County’s Planning Department is expected to recommend the collaborative approach that should be pursued to address SLR around Humboldt Bay. It may be as simple as an informal working group or as formal as a newly created regional agency. Whatever recommendation is forthcoming, the Grand Jury recommends it should be established as soon as possible due …
Social Science Research To Help Advance Regional Coordination And Collaboration Of Sea Level Rise Planning And Adaptation On Humboldt Bay, Kristen Orth-Gordinier
Social Science Research To Help Advance Regional Coordination And Collaboration Of Sea Level Rise Planning And Adaptation On Humboldt Bay, Kristen Orth-Gordinier
Student Projects
Humboldt Bay is experiencing the fastest rate of relative sea level rise in California and is likely to experience severe sea level rise (SLR) flooding within the next two decades. The Humboldt Bay shoreline is owned and governed by a patchwork of entities with different missions and jurisdictions so coordination of SLR planning will be critical because flooding of hydrologic areas from tidal waters can cross political boundaries. The goal of this project was to conduct social science research that can inform and advance the development of regional coordination and collaboration related to SLR in Humboldt Bay. To do this, …
College Street Journal (May 2022), College Of The Holy Cross
College Street Journal (May 2022), College Of The Holy Cross
College Street Journal
College Street Journal serves as a student platform for business-related news, opportunities and resources at Holy Cross. Readers will discover a broad range of important topics from relevant news and economic issues, career development opportunities and advice, as well as Ciocca center and campus-wide opportunities to grow outside of the classroom.
Highlights of this edition include an interview with Prof. David Chu, Dining Dollars, academic inflation,an alumni interview with Matt Blake, and a faculty editorial.
Synthesis, Characterization, And Evaluation Of Amphiphilic Cell-Penetrating Peptides As Sirna Delivery Tools For Cancer Therapy, Muhammad Imran Sajid
Synthesis, Characterization, And Evaluation Of Amphiphilic Cell-Penetrating Peptides As Sirna Delivery Tools For Cancer Therapy, Muhammad Imran Sajid
Pharmaceutical Sciences (PhD) Dissertations
Post-transcriptional gene silencing (PTGS), also termed as RNA interference (RNAi) possess a great therapeutic potential. Three siRNA-based products have been recently approved that have developed a renewed interest in the scientific community to explore this alternative therapeutic area rigorously. However, several challenges are limiting their use as a widespread therapeutic agent. The limitations include their membrane impermeability, short half-life, elimination by the kidney, entrapment by the reticuloendothelial system, sequestration by plasma proteins, endosomal trap, and off-target effects.
Several delivery systems and transfection agents have been investigated to address these challenges. Still, most of the systems suffer from toxicity and low …
Identifying Sars-Cov-2 Variants Of Concern Through Saliva- Based Rt-Qpcr By Targeting Recurrent Mutation Sites, Rachel E. Ham, Austin R. Smothers, Rui Che, Keegan J. Sell, Congyue Annie Peng, Delphine Dean
Identifying Sars-Cov-2 Variants Of Concern Through Saliva- Based Rt-Qpcr By Targeting Recurrent Mutation Sites, Rachel E. Ham, Austin R. Smothers, Rui Che, Keegan J. Sell, Congyue Annie Peng, Delphine Dean
Open Access Publishing Fund
SARS-CoV-2 variants of concern (VOCs) continue to pose a public health threat which necessitates a real-time monitoring strategy to complement whole genome sequencing. Thus, we investigated the efficacy of competitive probe RT-qPCR assays for six mutation sites identified in SARS-CoV-2 VOCs and, after validating the assays with synthetic RNA, performed these assays on positive saliva samples. When compared with whole genome sequence results, the SD69-70 and ORF1aD3675-3677 assays demonstrated 93.60 and 68.00% accuracy, respectively. The SNP assays (K417T, E484K, E484Q, L452R) demonstrated 99.20, 96.40, 99.60, and 96.80% accuracies, respectively. Lastly, we screened 345 positive saliva samples from 7 to 22 …
Scenes Of Screens, Scenes Of Sodomy: The Role And Impact Of The Folding Screen In Eighteenth-Century French Erotic Novels, Katherine Delony
Scenes Of Screens, Scenes Of Sodomy: The Role And Impact Of The Folding Screen In Eighteenth-Century French Erotic Novels, Katherine Delony
English Undergraduate Distinction Projects
This project provides an analysis of the folding screen as a literary agent and signifier which reflects the cultural happenings of the eighteenth century with specific emphasis on new ideas about queerness which arise in France during the eighteenth century. I will focus primarily on the Marquis de Sade’s (1740-1814) Justine, ou Les Malheurs de la vertu (1791) (as well as La Nouvelle Justine, 1797) and John Cleland’s (1709-1789) Le Fille de Joie (translated 1751) with reference to Jean-Louis Fougeret de Monbron’s (1706-1760) Margot la Ravaudeuse (1753), Sade’s Philosophie dans le boudoir Jean-François de Bastide’s (1724-1798) La …
Pandemic Transitions: The Impact Of Covid 19 On Hiring And Onboarding In Academic Libraries, Lauren M. Fletcher, Roslyn Grandy, Faythe Thurman, Rachel Whitney
Pandemic Transitions: The Impact Of Covid 19 On Hiring And Onboarding In Academic Libraries, Lauren M. Fletcher, Roslyn Grandy, Faythe Thurman, Rachel Whitney
Faculty & Staff Scholarship
Objectives: To explore how the COVID-19 pandemic has affected hiring and onboarding practices in academic libraries.
Methods: An embedded mixed-methods approach, utilizing grounded theory, was used to develop an online survey to identify changes that occurred in hiring and onboarding practices in academic libraries resulting from the COVID-19 pandemic. Participants were hiring managers (including human resources staff, library administration, search committee chairs, or library supervisors) in an academic library setting. Invitations to participate were sent to multiple academic library listservs and social media groups.
Results: Results will be analyzed to determine trends in hiring and onboarding practices …
Fixed-Dose Prothrombin Complex Concentrate Versus Weight-Based Dose For Reversal Of Factor Xa Inhibitors, Kevin Chau, Bryce Winn, Peter Martsin
Fixed-Dose Prothrombin Complex Concentrate Versus Weight-Based Dose For Reversal Of Factor Xa Inhibitors, Kevin Chau, Bryce Winn, Peter Martsin
Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022
No abstract provided.
Synthesis, Characterization, And Functionality Of Novel 2d Material Sn3p2, Cory Stephenson
Synthesis, Characterization, And Functionality Of Novel 2d Material Sn3p2, Cory Stephenson
Physics Undergraduate Honors Theses
In recent years, two-dimensional (2D) materials have gained a lot of attention due to their potential applications in devices and their promise to revolutionize technology. In our group, we are capable of synthesizing such materials and study their properties. I have discovered a new material of the tin-phosphorus family that displays the 2D layered structure and therefore shows potential to be used in future devices due to this reduced dimensionality from the typical three-dimensional counterpart. This 2D structure may allow for new phenomena to emerge as there is no longer any interatomic interactions along the z- axis. Under this motivation, …
Monitoring The M-Dwarf Host Stars Of Tess Exoplanet Candidates: Stellar Flares And Habitability, Ashley Lieber
Monitoring The M-Dwarf Host Stars Of Tess Exoplanet Candidates: Stellar Flares And Habitability, Ashley Lieber
Physics Undergraduate Honors Theses
In the search for life beyond our solar system, the study of M-dwarfs has become increasingly important due to their unique characteristics including their small size, flaring capabilities, and long lifespans. Their small size allows for exoplanet detection due to observable gravitational interactions, and the stellar flares could potentially trigger prebiotic life on exoplanets in the system. Lastly, their long lifespans may provide the conditions necessary to foster prebiotic life and the development of more complex organisms over time. Flare rate is a critical factor in determining the habitability of the exoplanet due to its potential to damage or incubate …
Forecasting Razorback Baseball Game Outcomes, Austin Raabe
Forecasting Razorback Baseball Game Outcomes, Austin Raabe
Information Systems Undergraduate Honors Theses
Despite the disappointing end to the 2021 Arkansas Razorback baseball year, the team’s success provided hog fans something to look forward to next season. While they will be without the 2021 Golden Spikes Award winner, Kevin Kopps, and four All-SEC team selections, the 2022 roster has promising new and returning talent. With fifty percent of the players who played significant time last year coming back (minimum ten hits or ten innings pitched), the arrival of several impact transfers from major conferences, and a recruiting class ranked in the top five according to Perfect Game, there is reason to believe that …
Social Isolation Interventions For Older, Underrepresented And Vulnerable Americans: A Descriptive Study Of Public Library Outreach Services During The Covid Pandemic, Sally Mathews Inglett
Social Isolation Interventions For Older, Underrepresented And Vulnerable Americans: A Descriptive Study Of Public Library Outreach Services During The Covid Pandemic, Sally Mathews Inglett
Leadership Education Capstones
The United States entered a state of lockdown in March 2020 in order slow the spread of the COVID-19 Novel Coronavirus. With this lockdown came mandatory social isolation, which was especially impactful for older, underrepresented and vulnerable Americans. Public libraries acted as community information centers and took on many unexpected roles to benefit the common good. This study identified these interventions through research and survey, and their relationship to Maslow’s hierarchy of needs (Maslow, 1943). This study also brought to light collaborative relationships between agencies, the redeployment of library staff and resources to meet these needs, the impact of the …
From Disengagement To Intervention: The Chinese Civil War, Korean War, And The Paradigm Shift Of The U.S. Foreign Policy In East Asia, Hosung Jung
History Student Projects
No abstract provided.
An Internet-Connected Community: How College Students Experience Residential Living In The Age Of New Media, Jared Hobson
An Internet-Connected Community: How College Students Experience Residential Living In The Age Of New Media, Jared Hobson
Master of Arts in Higher Education (MAHE) Theses
Higher education professionals, particularly those in the realm of Residence Life, are working with outdated knowledge. Emerging research is showing that the incoming cohorts of college students are fundamentally different than their predecessors because of new media technology's prevalence in our society. This study aims to determine if the usage and presence of internet-connected technology impacts how students experience community within their residence halls. In this context, students' sense of community is defined as the extent to which these individuals develop senses of attachment, belonging, and involvement.
Poverty, Social Isolation, Uselessness, And Loneliness: The Fears And Anxieties Of 19th-Century British Governesses, Lydia Pejovic
Poverty, Social Isolation, Uselessness, And Loneliness: The Fears And Anxieties Of 19th-Century British Governesses, Lydia Pejovic
English (MA) Theses
This essay focuses on the prevalent fears of governesses in nineteenth-century Britain: poverty and social isolation, uselessness/redundancy, and a life of loneliness. Through looking at Emma, Jane Eyre, and The Turn of the Screw, novels which span the century (their publication dates ranging from 1814-1898), and comparing them to the historical reality of many middle class women at the time, these fears are revealed to be quite valid. The fears and anxieties displayed by the characters in the three novels are reflected in statements made by former governesses (including Mary Wollstonecraft), and are likewise reinforced through census reports and common …
Reruns, Devann Donovan Gardner
Reruns, Devann Donovan Gardner
Graduate Theses
My thesis explores memory from the perspectives of both the adolescent and the adult. I find there are a multiplicity of truths that live within each memory. I am a visual artist who creates immersive installations and artworks that explore the plurality of truths held within memory. I offer a childlike whimsy in my visual aesthetic to invite the viewer in and pose a question for their adult side to consider. I question where the line is drawn between the child's memory and the adult's knowledge, and allow the viewer to decide which of those to believe. Imaginary landscapes and …
Cytotoxic Activity Of Non-Specific Lipid Transfer Protein (Nsltp1) And Proteomic Evaluation Of Heparin-Binding Proteins From Ajwain (Trachyspermum Ammi) Seeds, Saud Alshammari
Pharmaceutical Sciences (PhD) Dissertations
Trachyspermum ammi, commonly known as ajwain, is a member of the Apiaceae family. It is a therapeutic herbal spice with diverse pharmacological properties, used in traditional medicine for various ailments. However, all previous studies were conducted using small molecule extracts, leaving the protein’s bioactivity undiscovered. The present study demonstrated the antiproliferative activity of ajwain nsLTP1 in MCF-7, AsPC-1, and MCF10A cell lines and its structural stability in human serum and high-temperature conditions. The antiproliferative activity of ajwain nsLTP1 was evaluated in MCF-7 and AsPC-1 cell lines using an MTT assay. Annexin V-FITC and PI staining were used to detect the …
The Predictability Of Faculty Participation In Professional Development Programs Using Demographic, Academic, And Occupational Factors In Higher Education, Dibande Anna Itoe
The Predictability Of Faculty Participation In Professional Development Programs Using Demographic, Academic, And Occupational Factors In Higher Education, Dibande Anna Itoe
Dissertations (2016-Present)
The purpose of this study was to determine if there exist any predictive relationships between faculty demographic, academic, and occupational factors, and faculty participation in professional development programs. Despite the established benefits of faculty participating in professional development programs and its corresponding impact on student learning and graduation rates, a critical issue for professional development centers has been how to attract and motivate faculty to participate in these programs (James Jacob et. al., 2019). A correlational research procedure was used as the structural framework for conducting this study, and the population of interest were higher education faculty from two private …
Discovery Of Ojt010 As A Novel Inhibitor Of Severe Acute Respiratory Syndrome Coronavirus 2, Manvir Kaur
Discovery Of Ojt010 As A Novel Inhibitor Of Severe Acute Respiratory Syndrome Coronavirus 2, Manvir Kaur
Dissertations (2016-Present)
The current pandemic of coronavirus disease (COVID-19) caused by the highly infectious pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a global public health challenge. The emergence of deadly SARS-CoV-2 variants with mutations on the viral genes has made it more imperative to discover therapeutics that target the host receptors for COVID-19 treatment. Therefore, our research has targeted the critical host entry receptors: Angiotensin-converting enzyme-2 (ACE2) for SARS-CoV-2 entry into the human cells. SARS-CoV-2 is an enveloped RNA beta coronavirus that infects human cells via interaction with the ACE2 receptor, followed by viral replication and virus dissemination. Spike protein …
Organizational Change Process Milwaukee - Needs Assessment Summary, Quality Improvement Center For Workforce Development
Organizational Change Process Milwaukee - Needs Assessment Summary, Quality Improvement Center For Workforce Development
Other QIC-WD Products
Exploration of Needs
The Quality Improvement Center for Workforce Development (QIC-WD) worked with the Division of Milwaukee Child Protective Services (DMCPS) to conduct a needs assessment. A variety of information was explored to learn about the current workforce and the agency’s workforce practices, including 1) recruitment, hiring, and retention metrics and processes, 2) organizational culture and climate, and 3) other workforce processes and initiatives, such as onboarding, mentoring, supervision, performance management, and employee recognition. More specifically, four major types of information were considered: 1) objective data from various agency databases and reports; 2) subjective perceptions of staff and supervisors, …
Subset Selection Of Ε- Better Exponential Populations Under Heteroscedasticity, Anju Goyal, A. N. Gill, Vishal Maurya
Subset Selection Of Ε- Better Exponential Populations Under Heteroscedasticity, Anju Goyal, A. N. Gill, Vishal Maurya
Journal of Statistics Applications & Probability
Suppose we have $k( \geq 2)$independent processes/populations/sources/ treatments such that the data from $i^{th}$ treatment follow two-parameter exponential distribution with location parameter $\mu_i$ and scale parameter $\theta_i$, denoted $E(\mu_i,\theta_i )$, $i=1,\dots, k$. The location parameters $\mu_1, \dots, \mu_k$ and scale parameters $\theta_1, \dots, \theta_k$ are unknown and possibly unequal. Let $\underline{\delta}=(\mu_1 , \dots ,\mu_k, \theta_1, \dots \theta_k ) \in R^k \times R_+^k =\Omega $ and $\mu_{[k]} =max_{1\leq i \leq k}\mu_{i}$. For a given $\epsilon_1>0$, we define a set of good populations as $G=\{i:\mu_i \geq \mu_{[k]}-\epsilon_1 \}$. In this paper two-stage and one-stage subset selection procedures have been proposed to …
On Poisson Weighted Pranav Distribution Applicable To Count Data, Showkat Ahmad Dar, Anwar Hassan, Peer Bilal Ahmad, Mansour Lotayif
On Poisson Weighted Pranav Distribution Applicable To Count Data, Showkat Ahmad Dar, Anwar Hassan, Peer Bilal Ahmad, Mansour Lotayif
Journal of Statistics Applications & Probability
In this paper, we obtained a new model for count data by compounding of Poisson distribution(PD) with Weighted Pranav Distribution (WPD). Important mathematical and statistical properties of the distribution have been derived and discussed.Then, parameter estimation is discussed using maximum likelihood method of estimation. Finally, real data set is analyzed to investigate the suitability of the proposed distribution in modeling count data.
A New Class Of Distributions With Applications To Complete Data And Survival Data With Long-Term Survivors, M. M. E. Abd El-Monsef, M. M. El-Awady, M. M. Seyam
A New Class Of Distributions With Applications To Complete Data And Survival Data With Long-Term Survivors, M. M. E. Abd El-Monsef, M. M. El-Awady, M. M. Seyam
Journal of Statistics Applications & Probability
The exponential power distribution (EP) is a lifetime model that can exhibit increasing and bathtub hazard rate function. This paper aims to propose a new class of distributions called the exponential power power series (EPPS) class of distributions. The hazard function of the proposed class can be increasing, decreasing, modified bathtub (increasing-decreasing-increasing) and bathtub shaped. Among others, the exponential power geometric (EPG) distribution is presented as a special case of the proposed family. A defective version of EPG distribution is defined to estimate the fraction of long-term survivors in a population. The moments of the defective EPG distribution are obtained. …