Digital Commons Network^™

Challenges And Supports Of Principals’ Implementation Of Social-Emotional Learning, Nikomar Mosley

Walden Dissertations and Doctoral Studies

School districts throughout the United States are increasingly implementing social and emotional learning (SEL). The problem addressed in this study is that K-12 principals are struggling with the mandated implementation of SEL at Northeastern School District (NSD), a large, diverse urban school district. Guided by the collaborative for academic, social, and emotional learning competency and implementation frameworks, the purpose of this qualitative study was to explore K-12 principals’ experiences with the mandated implementation of SEL at NSD. For this basic qualitative study, semistructured interviews were conducted with 10 principals. Through thematic analysis, the following themes emerged: (a) SEL is not …

Celf1 Is A Non-Canonical Eif4e Binding Protein That Promotes Translation Of Epithelial-Mesenchymal Transition Effector Mrnas, Arindam Chaudhury, Natee Kongchan, Shebna A Massey, Rajesh Sharma, Rituraj Pal, Na Zhao, Phoebe Tsoi, Yingmin Zhu, Emuejevoke Olokpa, Sufeng Mao, Sonia Del Rincon, Lucas C Reineke, Richard E Lloyd, Marco Sardiello, Jeffrey M Rosen, Choel Kim, Josephine C Ferreon, Joel R Neilson

Faculty, Staff and Students Publications

Mounting evidence is revealing an increasing complexity of gene regulation at the level of messenger RNA (mRNA) translation. Within mammalian cells, canonical cap-dependent mRNA translation depends on the eIF4F complex, consisting of the m7G mRNA cap-binding protein eukaryotic initiation factor 4E (eIF4E), the helicase eIF4A (eIF4A), and the eIF4G (eIF4G1) scaffolding protein. eIF4G1 additionally binds poly(A) binding protein (PABPC1) to facilitate mRNA circularization and nucleates pre-translation initiation complex assembly to initiate ribosomal scanning. In breast epithelial cells, the CELF1 RNA-binding protein specifically promotes the translation of select epithelial-to-mesenchymal transition (EMT) effector mRNAs by binding GU-rich elements (GREs) within their 3' …

Novel Csf Biomarkers For Facilitating Diagnosis Of Cns-Hlh From Other Neuroinflammatory Disorders, Sharat Chandra, Kenneth D Greis, Somchai Chutipongtanate, Nathan Luebbering, Aaron Webster, Kelsey E Poisson, Kristen S Fisher, Kristi Smiley, Rebecca A Marsh, Michael B Jordan, Stella M Davies

Faculty, Staff and Students Publications

Central nervous system (CNS)-hemophagocytic lymphohistiocytosis (HLH) can mimic other neuroinflammatory disorders (ONID), often leading to misdiagnosis. Current diagnostic studies do not reliably distinguish CNS-HLH from ONID. We hypothesized that novel cerebrospinal fluid (CSF) biomarkers identified using unbiased proteomic analysis can facilitate diagnosis of CNS-HLH from ONID. Banked CSF samples were categorized into 3 groups, CNS-HLH, ONID, and controls without CNS inflammation. Proteomic analysis was performed on 25 samples per group (total N = 75). Proteins demonstrating significant changes (>1.5-fold higher and P< .05) in the CNS-HLH compared with ONID and associated with HLH pathophysiology were selected as candidate biomarkers. Cross-platform validation of candidate biomarkers, along with known biomarkers CXCL9 and osteopontin, was performed using enzyme-linked immunosorbent assay (ELISA). One hundred twenty-two proteins were identified on CSF proteomic analysis at 99% confidence. Of these, 10 proteins demonstrated a >1.5-fold change with a P< .05 in CNS-HLH compared with ONID. SerpinG1, lysozyme, and CD14 were selected as candidate biomarkers. ELISA confirmed significant elevation of all 5 biomarkers in CNS-HLH relative to ONID. Median SerpinG1 levels were1242.9 ng/mL in CNS-HLH vs 292.2 ng/mL in ONID (P ≤ .001), lysozyme 222.2 ng/mL vs 65.6 ng/mL (P = .001), and CD14 180.3 ng/mL vs 64.5 ng/mL (P ≤ .001). Median CXCL9 levels were 223.7 ng/mL in CNS-HLH vs 15.5 ng/mL in ONID (P ≤ .001), and osteopontin levels were 356.5 ng/mL vs 92.9 ng/mL (P = .001). These findings demonstrate that novel CSF biomarkers SerpinG1, lysozyme, CD14, and CXCL9 can facilitate diagnosis of CNS-HLH from ONID.

"The Only Place I Feel Understood": A Mixed Methods Survey Of Adolescent And Caregiver Perspectives On Social Media And Parental Controls, Melanie Watt Ramos, Constance M Wiemann, Lauren A Bretz

Faculty, Staff and Students Publications

Purpose

Methods

Results

Staff Education For Hypertension Diagnosis, Management, And Treatment, Philomena Ifeyinwa Chinemelu

Walden Dissertations and Doctoral Studies

Hypertension (HTN) is a significant public health concern, and educating nursing staff is crucial to improving patient outcomes and supporting public health initiatives. This staff education project focused on improving the quality of hypertension management by empowering nurses to provide evidence-based, patient-centered care. The practice-focused question is as follows: Will HTN education improve staff knowledge of HTN diagnosis, treatment, and management? I employed a quantitative pre-test/post-test design to measure changes in staff (n = 10) knowledge before and after training. Descriptive statistics measure knowledge gain and the effectiveness of educational strategies. The pre-test percentage of correct answers improved from 79% …

Staff Education To Reduce Compassion Fatigue In Acute Care Staff Nurses, Kamala C. Mcgee

Walden Dissertations and Doctoral Studies

Compassion fatigue (CF), burnout, and moral distress are common in high-acuity nursing environments, yet nurses are rarely taught how to recognize or manage these challenges. The guiding question for this staff education project was about whether education focused on CF and mindfulness-based coping strategies would improve nurses’ knowledge and attitudes in an acute care VA medical center. Posteducation results (n = 20) showed meaningful, statistically significant improvements. Familiarity with CF increased from baseline (M = 2.35; SD = 1.04) to post implementation (M = 3.75; SD = .91), t(19) = −5.085, p < .001. Confidence in recognizing CF in oneself improved from baseline (M = 2.6; SD = .875) to post implementation (M = 3.60; SD = .821), p = .004. Confidence in recognizing CF in colleagues increased from baseline (M = 2.40; SD = .821) to postimplementation (M = 3.15; SD = .671), p = .012. Agreement that seeking help is a sign of weakness decreased from baseline (M = 2.00; SD = .503) to postimplementation (M = 1.40; SD = .951), p = .024. Although perceptions of organizational support did not change, nurses reported greater use of mindfulness, peer support, and boundary setting, supporting nurse wellbeing and psychological safety. Several recommendations emerge from this project. CF education should be integrated into routine staff development, annual competencies, and onboarding for new nurses. By reducing stigma around seeking help and promoting peer awareness, this work supports fostering a workplace culture where all nurses feel safe, supported, and valued, a positive social change.

Effective Mentoring Strategies For Career Advancement For Mid- And Senior-Level Scientific Professionals In The Biotechnology Industry, Rachel Ayekor Hanson

Walden Dissertations and Doctoral Studies

Leaders of biotechnology organizations struggle to retain and promote experienced scientific professionals, thereby weakening innovation and long-term competitiveness. Biotechnology leaders are concerned about the successful development and retention of mid- and senior-level professionals as they move from technical to leadership roles to improve innovation and long-term competitiveness. Grounded in Kram’s mentoring theory and Ragins’s diversity and inclusion framework, the purpose of this qualitative pragmatic inquiry was to identify and explore mentoring strategies effectively implemented for biotech organization leaders, tailored to mid- and senior-level scientific professionals, to promote career progression and contribute to organizational performance. The participants were six biotechnology leaders …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

An Evening Book Talk: Austrian Again, Cardozo Law Institute In Holocaust And Human Rights (Clihhr), Anne Hand, Evelyn Konrad

2026 Event Invitations

Please join the Cardozo Law Institute in Holocaust and Human Rights for a special book talk featuring acclaimed author Anne Hand, discussing her memoir Austrian Again.

The program will be moderated by Evelyn Konrad ’05, a Cardozo alumna and Holocaust survivor, who will join the conversation and share her personal reflections.

In this captivating and deeply personal work, Hand sets out to uncover her family’s long-hidden history during the Holocaust while pursuing Austrian citizenship. As Austria opens the door to restored citizenship for descendants of those victimized by the Nazi and Austrofascist regimes, Anne digs through fragments of family stories …

Raising The Standard In Transition To Practice With Interprofessional Collaboration In A Healthy Work Environment, Grace Sekayan, Ghada Dunbar

Creating Healthy Work Environments (CHWE)

The success of the Perinatal Transition to Practice (TTP) Program across a multi-site integrated health system is built on the pillars of The Standards of Healthy Work Environments, American Nurses Credentialling Center (ANCC) Practice Transition Accreditation Program (PTAP)² domains, and Interprofessional Education Collaborative ⁴ (IPEC). This glimpse of the Perinatal TTP Program will provide insight on three of the six American Association of Critical-Care Nurses essential standards¹ that support communication, professional development, and the essence of nursing excellence. To support the transition of experienced nurse from novice to expert⁷ in a new specialty setting Skilled Communication, True …

Nitrogenated Graphene Quantum Dot-Derived Copper Single-Atom Catalyst For Oxygen Reduction Reaction, Dawatage Shashika Madushani Perera, Prakhar Sharma, Ayanthi Thisera, Nadeesha Kothalawala, Matthew G. Boebinger, Beth S. Guiton, Doo Young Kim

Chemistry Faculty Publications

Despite the promise of fuel cells as sustainable energy conversion technologies, their widespread adoption is hindered by the high cost of platinum group metal (PGM) catalysts, particularly for catalyzing the oxygen reduction reaction (ORR) at the cathode. Here, we report copper-based single-atom catalysts (Cu-SACs) as cost-effective non-PGM alternatives for ORR. The catalysts were synthesized via simple pyrolysis of pyrene-derived amine-terminated graphene quantum dots (GQDs) in the presence of nitrogen and metal precursors. The abundant nitrogen functionality in GQDs effectively stabilized isolated Cu atoms during their conversion to porous carbon. A subsequent acid-washing step yielded a high density of atomically dispersed …

Healthy Work Environment: A Positive Change In The Healthcare System, Rajveer Kaur, Jiji Andrews

Creating Healthy Work Environments (CHWE)

It empowered the nurses through structural and psychological infrastructure, paying attention to the detailed work, applying the knowledge from other disciplines to incorporate in the nursing science for evidence-based practice, and utilizing skills in the nursing practice for healthy work environment engagement. Due to the nursing shortage, nursing leaders must understand a healthy workplace for clinical nurses and drive a positive change in the environment by using educational programs. A study was conducted in the hospital on a medical-surgical unit to evaluate the effects of Authentic leadership and actions producing positive patient outcomes. The study results include psychological empowerment, improved …

Green Nanoremediation Of Phytogenic Copper Oxide Nanoparticles For Concurrent Organic Pollutant Degradation In Industrial Wastewaters And Antibacterial Activity, Adel Hussain Talib, Wijdan Hameed Al-Kubaisi, Safaa A. S. Al-Qaysi, Zainab Anwar Ali

Baghdad Science Journal

In the present investigation, culture A. niger was used for the biosynthesis of CuO-NPs using mango (Mangifera indica) leaves aqueous extract. This method of green synthesis is simple, more environment friendly and easy to scaled up. The obtained CuO-NPs were characterized using FT-IR, XRD, TEM, EDX and DLS to evaluate their structure, morphology, elemental composition, and particle size distribution. These findings verify the generation of spherical, crystalline CuO-NPs with an average size of 35.1 nm. The biosynthesized plant-based CuO-NPs showed potential antimicrobial and catalytic, with the higher concentration (till 6.0 mg/mL) having effect better the effect. When used for wastewater …

Laser-Focusing Defense Capabilities, James Giordano

Strategic Insights

This commentary examines the growing strategic importance of high-energy laser weapons as part of modern multidomain defense and deterrence. As unmanned systems, hypersonic delivery platforms, and electronic warfare capabilities expand the speed and scale of modern conflict, traditional kinetic defenses face increasing limitations. Directed-energy systems, particularly high-energy lasers, offer scalable, precise, and cost-effective countermeasures against emerging threats. While laser weapons are not a universal solution, continued investment in power generation, beam control, artificial intelligence integration, and operational doctrine could allow these systems to play a central role in future defense architectures. Properly developed and integrated, laser technologies could strengthen deterrence, …

Hybrid Vision Transformer–Cnn Framework For Alzheimer’S Disease Cell Type Classification: A Comparative Study With Vision–Language Models, Md Easin Hasan, Md Tahmid Hasan Fuad, Omar Sharif, Amy Wagler

School of Mathematical & Statistical Sciences Faculty Publications

Accurate identification of Alzheimer’s disease (AD)-related cellular characteristics from microscopy images is essential for understanding neurodegenerative mechanisms at the cellular level. While most computational approaches focus on macroscopic neuroimaging modalities, cell type classification from microscopy remains relatively underexplored. In this study, we propose a hybrid vision transformer–convolutional neural network (ViT–CNN) framework that integrates DeiT-Small and EfficientNet-B7 to classify three AD-related cell types—astrocytes, cortical neurons, and SH-SY5Y neuroblastoma cells—from phase-contrast microscopy images. We perform a comparative evaluation against conventional CNN architectures (DenseNet, ResNet, InceptionNet, and MobileNet) and prompt-based multimodal vision–language models (GPT-5, GPT-4o, and Gemini 2.5-Flash) using zero-shot, few-shot, and chain-of-thought …

Nursing Student Perceptions Of Clinical Experiences With Practicing Nurses: A Descriptive Research Study, Carolyn E. Smith, Jenna E. Davis

Creating Healthy Work Environments (CHWE)

Clinical education is an essential part of the nursing curriculum contributing to critical thinking skills and nursing judgment. The students’ experiences within the clinical setting sets a precedence for their future careers and how they interact with their peers and interprofessional team members (Mamaghani et al., 2019). Communication between the bedside nurses and the students is a key factor to student success and confidence at the bedside. The tone, topic, and timing of the conversation between students, nurses, and/or peers, may impact the student view of bedside nursing. Positive interactions and supportive feedback leads to improved patient care, clinical judgment, …

Student’S Experience With Cognitive Rehearsal To Address Incivility, Penny A. Sauer, Margaret M. Verzella

Creating Healthy Work Environments (CHWE)

Nurses need to be able to advocate for their patients, even if they face verbal abuse or incivility. Current literature indicates that 66.2%-95.1% of nurses experience verbal abuse (Dadfar & Lester, 2021) with younger, inexperienced nurses having higher levels of abuse (Zulfan et al., 2022). Nurses who face workplace violence, including verbal abuse, have higher levels of stress, impacting their mental and physical health (Sauer & McCoy, 2017).

A mixed-method study was conducted with undergraduate nursing students to determine their response to a simulation that included difficult communication with a healthcare provider. Students were provided with tools and strategies to …

Theoretical Contributions To A Positive Work Environment, Sharon Prawl

Creating Healthy Work Environments (CHWE)

Objectives: Examination of the success of nurse preceptors is moving toward the need for co-creation between nurse leaders and nurses in the role of nurse preceptors. The current nursing workforce has five generations in the cohort of healthcare workers: Silent Generation, Baby Boomers, Generation X, Millennials (Generation Y), and Generation Z (Bacon, 2023). Each group may have different characteristics and traits; supporting them can be challenging. As noted, the demographics of the workforce have changed. Therefore, Nurse Leaders (NL) must demonstrate inclusive leadership behaviors that result in practice environments where all individuals, diverse in their ages, experiences, and education, …

Organizational Trust And Burnout Among Registered Nurses And Patient Care Aides: A Qualitative Study, Katherine C. Brewer, Andrew Dierkes, Allison A. Norful

Creating Healthy Work Environments (CHWE)

Background: Healthcare worker wellbeing has emerged as a pivotal topic in workforce research. Organizational factors may impact well-being as much as individual and personal factors. One organizational determinant of well-being includes institutional trust; specifically, how the relationship between clinician and employer influences well-being (e.g., burnout). Institutional trust is an important factor in human caring professions, due to the moral and emotional nature of the work and the expectation for safety and provision among clinicians by employers. Existing clinician well-being research rarely studies institutional trust among registered nurses (RNs) and patient care aides (PCAs), despite their important frontline role in patient …

Musculoskeletal Infection Reporting And Data System (Mski-Rads): Reviewed And Explained, Angela He, Flavio Duarte Silva, Mina Guirguis, Erin F. Alaia, William B Morrison, Avneesh Chhabra

Department of Radiology Faculty Papers

A standardized guideline and scoring system are recommended for the imaging evaluation of musculoskeletal infections on MR imaging. The Musculoskeletal Infection Reporting and Data System (MSKI-RADS) is a recently developed and validated classification system using MR imaging that can be used to classify the severity and extent of musculoskeletal infections, improve radiology-pathology concordance, and outline the corresponding management recommendations. This review article explains MSKI-RADS and discusses the different elements of this system in detail with a review of pertinent literature so that the readers can apply it in their practices. The work outlines the technical considerations for optimal MR imaging …

A Probabilistic Deep Learning Framework For Retrieving Chlorophyll-A From Hyperspectral Imagery: Integrating Channel Attention And Mixture Density Networks, Wenzhao Li, Surendra Maharjan, Rejoice Thomas, Junde Chen, Hesham Morgan, Michael J. Garay, Olga V. Kalashnikova, Shahryar Fazli, Charles Ichoku, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Accurate monitoring of Chlorophyll-a (Chla) is critical for assessing aquatic ecosystem health, yet ecological complexity often leads to ambiguous spectral signatures in satellite data. Traditional deterministic models assume a one-to-one mapping between spectra and pigments, often failing to capture these high-dimensional analytical challenges. In this study, we propose a novel deep learning architecture, the Channel Attention-Mixture Density Network (CA-MDN), to retrieve Chla from the National Aeronautics and Space Administration (NASA) Earth Surface Mineral Dust Source Investigation (EMIT) hyperspectral mission. The CA-MDN integrates an attention mechanism to dynamically select ecologically relevant spectral bands and employs a probabilistic output layer to quantify …

The Path Forward For T Cell Engagers In Patients With Prostate Cancer, Sumit K. Subudhi, Bilal A. Siddiqui, Kevin K. Zarrabi, William K. Kelly, Charles G. Drake

Department of Medical Oncology Faculty Papers

T cell engagers (TCEs) recruit T cells to the tumor microenvironment (TME) to induce antitumor immune responses. TCEs have demonstrated promising clinical responses in patients with metastatic castration-resistant prostate cancer and have advanced into phase 3 clinical trials. Here we provide an overview of the mechanisms of action of TCEs, including both CD3-targeted and CD28-targeted agents, and review the clinical development of these agents for prostate cancer. We propose a path forward for TCEs in prostate cancer, in which innovative clinical trials will facilitate a biological understanding of mechanisms of efficacy and toxicity to inform: (1) development of predictive biomarkers …

Weaponizing The First Amendment: Captive Audience Laws Recast From Shield To Sword, Seth Freeman

Seattle University Law Review Online

This Comment examines the evolution and misuse of captive audience laws in the United States, particularly as they have shifted from narrow exceptions in First Amendment jurisprudence to expansive tools for ideological suppression. Originally designed to protect individuals from unavoidable and coercive speech, especially in private spaces like the home, captive audience laws have increasingly been utilized in regulating workplace speech, with a recent focus on suppressing conversations around diversity, equity, and inclusion (DEI). Through an analysis of foundational Supreme Court cases and an exploration of recent legislative trends, this Comment reveals how state legislatures have weaponized captive audience doctrine …

Mid-Size Firm And Private Sector Networking Fair, New York Law School

Academic Planning and Career Development

Tuesday, February 24, 2026

Anomalous Spontaneous Induction Of Magnetic And Electric Fields In Dense Quark Matter, Efrain J. Ferrer, Jose Miguel Perez-Fernandez

Physics & Astronomy Faculty Publications

In this paper, we will demonstrate that a dense quark-matter system in the dual chiral density wave (DCDW) phase behaves as a ferromagnet in the sense that its magnetic-field dependent magnetization remains different from zero even at 𝐵 →0. The corresponding permanent magnetization is a function of the baryonic chemical potential 𝜇, decreasing up to zero as 𝜇 increases in the range of intermediate densities (312  MeV⩽𝜇⩽342  MeV) and then increasing from zero in the higher density interval 490  MeV⩽𝜇⩽550  MeV. We will show that this system’s ability to generate permanent magnetization, together with the existence of the axial anomaly, …

Cle Program: Putting People At The Center Of Representation 2-24-2026, Roger Williams University School Of Law

School of Law Conferences, Lectures & Events

No abstract provided.

Granite State Issues: Guns In Colleges, Ice In Merrimack, Public School Choice Limits, Marijuana Legalization 2/24/2026, Unh Survey Center

All UNH Survey Center Polls

Majorities of New Hampshire residents oppose a proposed Immigration and Customs Enforcement (ICE) processing facility in Merrimack and the elimination of vaccine requirements in public schools. Pluralities oppose a bill allowing guns and other weapons at public colleges and universities and a bill prohibiting public school districts from limiting the number of students they accept from other districts or who wish to leave and go to another district. A majority approve of legalizing marijuana for recreational use. Overall, the most important problems facing New Hampshire are housing and taxes. Finally, Governor Kelly Ayotte’s approval rating has slipped to the lowest …

Foulkes Retains Lead In Ri Dem Gubernatorial Primary, Mckee Approval Falls To New Low 2/24/2026, Unh Survey Center

All UNH Survey Center Polls

Helena Foulkes remains the leader in the race for the Democratic nomination for Rhode Island governor, but a plurality of likely voters remain undecided. Neither the declared candidates nor possible late entrant and former Governor Gina Raimondo are particularly popular among likely Democratic primary voters, and very few want Raimondo to launch a new campaign for governor. On the Republican side, the declared candidates are not well-known among likely Republican primary voters, but there is strong interest in 2022 Republican nominee Ashley Kalus running again. Approval of Governor Dan McKee's performance as governor has fallen to an all-time low, but …

Risk Stratification Of Low-Dose Cytarabine And Venetoclax In Patients With Aml Ineligible For Intensive Chemotherapy, Andrew H Wei, Panayiotis Panayiotidis, Pau Montesinos, Kamel Laribi, Vladimir Ivanov, Inho Kim, Jan Novak, Rebecca Champion, Walter Fiedler, Maria Pagoni, Julie Bergeron, Stephen B Ting, Jing-Zhou Hou, Takahiro Yamauchi, Jianxiang Wang, Stephen A Strickland, Michael R Savona, Tara L Lin, Anoop Enjeti, Ing Soo Tiong, Sangmin Lee, Gail J Roboz, Relja Popovic, Qi Jiang, Zihuan Liu, Yan Sun, Wellington Mendes, Brenda Chyla, Courtney D Dinardo

Faculty, Staff and Student Publications

Prognostic risk categorization aids treatment selection for patients with acute myeloid leukemia (AML). Although the European LeukemiaNet (ELN) classifications (2017 and 2022) for AML have been used to stratify outcomes for patients receiving intensive chemotherapy, their application to patients receiving less intensive therapy, such as azacitidine plus venetoclax, has been less satisfactory. In response, a 4-gene classifier that stratifies older patients with AML unfit for intensive chemotherapy into those with higher benefit (wild type), intermediate benefit (FLT3-internal tandem duplication [ITD] or NRAS/KRAS mutation), or lower benefit (TP53 mutation) after azacitidine plus venetoclax treatment was developed. We hypothesized that this 4-gene …

Concordance Analysis Of Dna And Rna Profiling: The Md Anderson Impact2 Study In Precision Oncology, Stephanie T Schmidt, Mehmet A Baysal, Siqing Fu, David S Hong, Sarina A Piha-Paul, Aung Naing, Jordi Rodon Ahnert, Timothy A Yap, Ecaterina Elena Dumbrava, Jennifer Beck, Funda Meric-Bernstam, Apostolia Maria Tsimberidou

Faculty, Staff and Student Publications

DNA profiling is an established method for cancer treatment selection, while RNA profiling remains investigational. We explored associations between DNA and RNA alterations and between the number of genes with altered expression and overall survival (OS) using patient data from IMPACT2 (NCT02152254), a randomized study evaluating molecular profiling for guiding cancer therapy across tumor types. Molecular profiling, including DNA next-generation sequencing, was performed on all 829 patients in the IMPACT2 study. RNA profiling was performed by Tempus for 253 of 829 patients. We evaluated the concordance between DNA and RNA profiling, analyzed OS in 217 treated patients with …