Digital Commons Network^™

The Indications And Potential Complications Of Supplementing With Fat-Soluble Vitamins, Krista Thielges

Physician Assistant Scholarly Project Papers

There is a seemingly infinite list of available formations of over-the-counter supplements, including vitamins. According to Grand View Research, the nutritional supplement industry has grown in popularity in recent years, increasing its worth to an estimated 140 billion dollars in 2020 globally, with vitamins accounting for 31.4% of the revenue. An estimated half of Americans take a daily vitamin or supplement. With the increasing number of people supplementing, the incidence of disease should be trending down. This literature review focuses on fat-soluble vitamins, vitamin A, D, E, and K. Supplementation of these vitamins proposes the prevention of chronic diseases such …

Epigenetics As Primary Prevention Of Coronary Artery Disease, David Majewski

Physician Assistant Scholarly Project Papers

This systematic literature review intended to ascertain if epigenetic testing for the primary prevention of Coronary Artery Disease (CAD) decreases mortality compared to the current standard of care. This systemic review used PubMed and Cochrane medical databases to assess epigenetic variances and their association with CAD. The Medical Subject Headings (MeSH) terms used were as follows: CAD, genetics, epigenomics, diabetes, hypertension, obesity, dyslipidemia, primary prevention, and standard of care. Further limiting the search results to Randomized Control Trials (RCT’s), meta-analysis, peer-reviewed, and published within the last 10 years. Exclusion criteria included publications before 2011, articles that did not compare genetic …

Comparing Clozapine And Electroconvulsive Therapy In Refractory Schizophrenia, Anthony Alan Beaty

Physician Assistant Scholarly Project Papers

Schizophrenia is a complicated problem that millions of Americans struggle with and unfortunately, about 50 percent of schizophrenics become resistant to medication. It is common practice to try multiple drugs to combat this resistance and many patients are placed on clozapine or given electroconvulsive therapy (ECT) as a last resort. Research has shown that many are not receiving the benefits of these treatments due to adverse effects, negative public opinion, and difficulty executing high quality research studies particularly when it comes to ECT. As a result, a significant number of patients that would benefit from these interventions are suffering with …

Best Second Oral Agent To Metformin To Manage Type 2 Diabetes, Dhana Acharya

Physician Assistant Scholarly Project Papers

Diabetes is a major health concern in the United States with many long-term complications, such as heart disease, stroke, kidney failure, blindness, and amputation. According to the Center for Disease Control, as of 2020, 34.1 million of US adult had diabetes and 88 million were prediabetic. Due to the severe complications, it is important to manage diabetes with lifestyle changes and pharmacotherapies. Many oral agents such as metformin, sodium glucose transporter 2 inhibitors (SGLT2i), and sulfonylureas are used in the management of type II diabetes. Metformin is typically the first line pharmacotherapy. However, when metformin alone is not enough to …

Shore-To-Ship Drones: Relevance And Applicability Of Maritime Navigation Rules, Ali Movaghar, Jason Chuah

Journal of Maritime Law and Commerce

No abstract provided.

A Qualitative Review Of The Relationship Between Safety Management Systems (Sms) And Safety Culture In Multiple-Collegiate Aviation Programs, Anthony Robert Foster, Daniel Kwasi Adjekum

Aviation Faculty Publications

Safety Management Systems (SMS) implementation is currently a voluntary pursuit for collegiate aviation programs. Some programs have implemented SMS and others are beginning to consider it. An understanding of the impact of SMS on safety culture at institutions actively implementing SMS and the potential challenges posed can be useful to the entire collegiate aviation community. The safety culture perceptions across three collegiate aviation programs with varying levels and types of SMS implementation were explored through semi-structured interviews of students, certified flight instructors (CFI), and safety leaders. Emergent codes and subsequent themes derived from the semi-structured interviews suggest an apparent knowledge …

Reinventing Our Understanding Of The Left-Right Political Dichotomy: The Case Of Argentina, Sol Halle

International and Global Studies Undergraduate Honors Theses

What happens to a country’s political culture once populism takes root? Have Global North-centered methods of evaluation miscategorized Global South political party identification both historically and contemporaneously? As the world grapples with the continued rise of populism and its divisive rhetoric, scholars must thoroughly examine the movement’s spheres of influence beyond traditionally accepted frameworks. Understanding populist parties is vital, for they oftentimes create staggering disruptions within a nation’s political culture. These disturbances become starkly apparent in times of crises as challenges plunge everyday citizens deeper into the political sphere. The case of Argentina allows for an examination of the ways …

The Work Of La Via Campesina Regarding The Intersection Of Land Occupation And Food Sovereignty, Josephine Drydale

International and Global Studies Undergraduate Honors Theses

La Via Campesina (LVC), a global movement that supports small and local farmers and their communities, is one of the world’s largest food and agricultural rights movements and advocates for agricultural rights in terms of land, ecology, human rights, and more. LVC is known for its establishment of food sovereignty, defined as the right to control one’s production and consumption of food. This new concept placed them on the map, accompanied by their aggressive editorial and advocacy work against ideals they view as neoliberal and food policies that benefit large food moguls while disenfranchising the small farmer. The concept of …

The Last Leg: A Social Sustainability Assessment Of Ovine Agriculture, Sydney Golding

International and Global Studies Undergraduate Honors Theses

Post-war agricultural transformations and the rise of Sustainability discourses have dictated the trajectory of sector industries. The implications of agriculture in lateral policy schemes have neglected the careful consideration of the social health of farmers in decision-making processes, creating a greater divide between the interests of the state and our once revered providers. This study aims to capture the complexity of social matters in agriculture within the specific context of sheep farming in the United Kingdom and the United States and how the concurrent systems have adapted considering the impacts of relevant contemporary historical contexts. The principles of Janker, Mann, …

The International Perception Of The Irish Republican Army And Chechen Insurgency, Henry Forteith

International and Global Studies Undergraduate Honors Theses

This purpose of this project is to examine how the labels used to describe the Irish Republican Army and Chechen insurgency changed after certain acts of violence. This paper begins by describing the history of imperial subjugation of Ireland and Chechnya, as well as examining the similarities between the actions and motivations of the IRA and Chechen insurgency. Then, to study the change in language to describe these groups, two searches were conducted into the New York Times and International Newsstream databases. The first search examined articles about the IRA and Chechen insurgency published between 1998 and 2009, while the …

A Tale Of Two Libraries: A History Of The Public Library Systems Of Atlanta, Ga And Baltimore, Md And How Libraries Across America Adapt To Their Communities, Gigi Powell

History Undergraduate Honors Theses

Public libraries are a staple American institution, and one that was created to adapt and react to its surrounding communities. Public libraries are unique in their ability to anticipate and fill a community’s needs, as evidenced by their constant evolution to remain relevant and provide up- to-date services to all users. To highlight this evolution, librarians from both the Fulton County Public Library System in Atlanta, GA and the Enoch Pratt Free Library system were interviewed to gauge what the library’s role is in a modern world, in a world newly ravaged by COVID-19, and how that role has evolved …

The Political Power Of Museums: A Case Study On The Museum Of Spanish Colonial Art, Emily Snyder

History Undergraduate Honors Theses

Museums hold an esteemed position that grants validity to the objects and history held within them based solely on their inherent authority as institutions. This makes the analysis of what museums portray incredibly important given the extent of people’s belief that they hold the power to determine authoritative truth concerning art, history, and society. In the late 1970s, museums underwent a period of change tied to becoming more pluralistic. Beginning in the 1990s, many museums touted their postcolonial status in the wake of their inclusion of and collaboration with traditionally outsider communities. Despite this change appearing to create more diverse …

World Changers Made Here., Andrea Luxton

Lake Union Herald

No abstract provided.

Ocul Collaborative Futures (Cf) Decolonizing Descriptions Working Group Final Report, Erin Johnson, F. Tim Knight, Antonio Muñoz Gómez

Librarian Publications & Presentations

The broad objective of the working group is to develop recommendations on how to make descriptive metadata in Omni, the Collaborative Futures (CF) shared library services platform, more accurately and respectfully reflect Indigenous Peoples, knowledges, and contexts.

The following report was created by the OCUL-CF Decolonizing Descriptions Working Group and submitted to the OCUL-CF Metadata Management and Standards Committee as per its Terms of Reference.

In section 1 of the report, we have included a set of recommendations organized as follows:

● Recommendations on relationship building and consultation: The Working Group recognized that without this step, this work cannot advance …

The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples, Qamar Alshammari

Pharmaceutical Sciences (PhD) Dissertations

The wavelength is used to identify the exact location and quantify the number of molecules in the spectral imaging system. It aids in identifying materials and studying their quantities by examining how they interact with light. A traditional spectrometer provides spectrum information of chemical compounds, while standard imaging provides the intensity at each pixel of the image. Spectral imaging (SI) combines these two aspects by equipping intensity and spectral data for each pixel. In biomedical research, it is important to assess the inorganics/organics molecules to understand drug activity, cellular toxicity, and distribution. Using the microscopy technique, we found for the …

Newsletter May 2022, Mandarin Garden Club

Mandarin Garden Club Newsletters

Club News

Why Renegotiation?: Renewal Of The South Korea-Chile Bilateral Free Trade Agreement, Montserrat Bugueno

International Studies (MA) Theses

This thesis project explores the motivations behind the bilateral free trade agreement (FTA) renegotiation between Chile and South Korea. Existing studies have examined the reasons and outcomes of creating the initial Chile-South Korea FTA, but they have not focused on renegotiations between the two countries. A few investigations on renegotiations have focused on diversifying their exports and expanding their markets in each other's regions. However, most research lacks further exploration of both countries' market security concerns. By analyzing official government documents and conducting three semi-structured interviews with government officials and experts in the field, I argue that the current protectionist …

Tennessee Abortion Policy Summary - May 2022, Center For Applied Reasearch And Evaluation In Women's Health, East Tennessee State University

Center for Applied Research and Evaluation (CARE) in Women's Health Issue Briefs

With the U.S. Supreme Court anticipated to overturn the 1973 Roe v. Wade decision (and the modifications to that decision by Planned Parenthood of Southeastern Pennsylvania v. Casey from 1992), the protection, regulation, or prohibition of abortion would likely default to state laws and state constitutions. Therefore, to understand how this upcoming Supreme Court decision could impact access to abortion in Tennessee, it is useful to examine both key current state laws in effect related to abortion access, as well as the current state of access to abortion in Tennessee. This brief intends only to summarize current Tennessee state laws …

The Design, Prototype, And Testing Of A Robotic Prosthetic Leg, Michael Davidson

Loma Linda University Electronic Theses, Dissertations & Projects

Since antiquity, health professionals have sought ways to provide and improve prosthetic devices to ease the suffering of those living with limb loss. Mid-century modern engineering techniques, in part, developed and funded by the American industrial war effort, led to numerous innovations and standardization of mass-customized products. Followed by the Digital Revolution, we are now experiencing the roboticization of prosthetic limbs. As innovations have come and gone, some essential technologies have been forgotten or ignored. Many successful products have been commercialized, but unfortunately, they are often rationed to those who need them most. Here we present a prototype device based …

Strategies For Protection Of The Blood Brain Barrier In Rodent Models Of Intracerebral Hemorrhage, Derek Sunil Nowrangi

Loma Linda University Electronic Theses, Dissertations & Projects

Intracerebral Hemorrhage (ICH) is a devastating disease that causes a cascade of both mechanical and molecular injury to the central nervous system. It is a debilitating disease that has no well-established treatments, thus leaving an important area to study the pathophysiology of the disease so that new clinically translatable treatments can be found. In the development of translational treatments in experimental ICH, several challenges exist including the designing of studies, method to deliver drugs, proper dosages, and development of models. In our exploration to establish new therapies for ICH, we studied several methods and models that may help to develop …

An Investigation Of The Anti-Stemness Actions Of Two Mirnas After Their Induction By Aminoflavone In Luminal A Breast Cancer, Nicole Ursula Rumbidzai Mavingire

Loma Linda University Electronic Theses, Dissertations & Projects

Approximately 40% of estrogen receptor positive breast cancer (BC) patients develop resistance to endocrine therapy (ET) agents like tamoxifen (Tam). Resistance promotes metastasis, recurrence, and death since metastatic BC is often incurable. Breast cancer stem cells (CSCs) greatly contribute to disease progression and drug resistance. We previously showed that aryl hydrocarbon receptor (AhR) agonist aminoflavone (AF) inhibits the expression of CSC biomarker α6-integrin (ITGA6) to disrupt the formation of endocrine-sensitive and -resistant luminal A mammospheres. In this study, we performed miRNAsequencing analysis of luminal A MCF-7 and MCF-7TamR mammospheres before and after AF treatment to further develop the mechanism of …

Through The Leaves: Understanding Population Genetic Structure Of Clematis Morefieldii, Keith Andrew Greenway

Honors Capstone Projects and Theses

No abstract provided.

Digital Commons @ Andrews University Annual Report 2021-2022, Terry Dwain Robertson

Library Administration and Marketing

Report covers May 2020-April 2021

Table of Contents

• About the Digital Commons @ Andrews University
• Five Millionth Download
• Global Impact
• Serving the SDA World Church
• “Letting Your Light Shine”: Faculty Scholarship in SelectedWorks
• 2000 Faculty Publications Added

Authentic Leadership As Practiced By Wabanaki Leaders, Ashlyn Tomer Ma

Leadership Studies

Native American leaders of the Wabanaki community can provide great insight on how to build positive close-knit relationships within a community. Previous research has focused on other tribal nations such as the Cherokee and servant leadership. But few studies have explored authentic leadership in the Wabanaki community. Authentic leadership occurs naturally in the Wabanaki Nation through their cultural upbringing and the leaders' authenticity projects back into the community. This phenomenology study explores authentic leadership within the Wabanaki Nation and how it contributes to the cultivation of positive relationships within the community. Ten leaders and advocates of the Wabanaki community participated. …

A Machine-Verified Proof Of Linearizability For A Queue Algorithm, Ugur Yavuz

Dartmouth College Master’s Theses

Proofs of linearizability are typically intricate and lengthy, and readers may find it difficult to verify their correctness. We present a unique technique for producing proofs of linearizability that are fully verifiable by a mechanical proof system, thereby eliminating the need for any manual verification. Specifically, we reduce the burden of proving linearizable object implementations correct to the proof of a particular invariant whose correctness can be shown inductively. Noting that the latter is a task that many proof systems (such as the TLA+ Proof System we chose to work with) are well-suited to handle, this technique allows us to …

Fungal Fruiting And Dispersal Following Timber Harvest, Benjamin William Borgmann-Winter

Master's Theses and Capstones

Forest-dwelling fungi are critical to ecosystem function in their roles as decomposers and nutrient cyclers, food sources, pathogens, and mycorrhizal symbionts. In northern New England, a region with a substantial timber industry, the degree to which fungal communities are resilient to timber harvest, as well as their ability to recolonize post-disturbance, may impact ecosystem function and forest regeneration. In this thesis, we investigate the impacts of (1) timber harvest on fungal fruiting, an important element of fungal reproduction, and (2) the dispersal mechanisms by which fungi may re-colonize harvested areas. In Chapter 1, we investigate the impact of timber harvest …

Gli3 And P300: Modulating Inflammatory Cytokine Production In Monocytes, Storm Devin Gardner

Master's Theses and Capstones

GLI3 is an important protein traditionally found in the Sonic Hedgehog pathway. It is involved in numerous events that take place during embryogenesis such as the differentiation and patterning of cells in the body. Monocytes are important innate immune cells which infiltrate the site of inflammation when a pathogen invades our body. Gli3 has also been shown to be upregulated in monocytes following pathogen stimulation, suggesting Gli3 could have an important role in mediating the release of inflammatory signals known as cytokines. The histone acetylase protein p300 traditionally acetylates histones to epigenetically modify them to allow DNA unwinding and subsequently …

Improving Larval And Juvenile Lumpfish, Cyclopterus Lumpus, Aquaculture: Nutrition And Growing Conditions, Nathaniel Spada

Master's Theses and Capstones

Salmonids play a major role in aquaculture globally and their production is expected to increase as the human population rises and wild fish stocks decline. Sea lice infestation is the largest economic burdens to salmonid net pen aquaculture with hundreds-of-millions of dollars lost due to the treatment, labor, and loss of biomass associated with these parasitic copepods. Chemotherapeutics were originally used to treat these infestations, but their effects on nontarget species resulted in them being banned in many countries. Many salmonid farmers now utilize cleanerfish technology to resolve this financial stressor. Lumpfish (Cyclopterus lumpus) are efficient delousers in salmonid aquaculture …

Uv Sulfite Advanced Reduction Process For Pfos Transformation In Wastewater Treatment, Cassidy Rae Yates

Master's Theses and Capstones

Most nutrients and contaminants within municipal wastewaters are removed through physical, chemical, and biological treatment methods. Per- and polyfluoroalkyl substances (PFAS) are a class of contaminants of emerging concern (CECs) that are concentrated in wastewater treatment facilities (WWTFs) from municipal, industrial, and commercial sources in communities. PFAS are poorly removed in conventional municipal wastewater treatment because these facilities are generally not designed for treatment of low-level CECs. Some PFAS leave WWTFs through aqueous effluent, while others partition to solids and are handled in sludges due to properties based on the degree of fluorination, chain length, and headgroup. As the last …

Bivalve Restoration Suitability Analysis, Sara Bandali, Kayla Garcia, Derek Bostelman, Georgina Quinn

Student Projects

Cal Poly Humboldt Environmental Science and Management: ESM 475 Planning and Policy Capstone Practicum.

The goal of this project is to provide Humboldt Baykeeper with a report of potential designs, sites, benefits, and stakeholder opinions related to developing a native Olympia oyster and clam garden restoration pilot project on Wigi. This suitability analysis will examine several different locations across the bay and compare the feasibility of (1) an Olympia oyster restoration, (2) an Olympia oyster living shoreline restoration for sea-level rise, and (3) a clam garden restoration. Based on our research, we will provide an analysis of four sites in …