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The Kalamazoo Promise “Sweet 16," Summary Study Results: 16 Key Findings From 16 Years Studying The Kalamazoo Promise, Kathleen Bolter, Isabel Mcmullen

Reports

No abstract provided.

Transition To A Night Float System In Ophthalmology Residency: Perceptions Of Resident Wellness And Performance, Sahil Aggarwal, C. Ellis Wisely, Andrew Gross, Pratap Challa

Journal of Academic Ophthalmology

Abstract

Purpose The purpose of this study is to characterize the influence of a new night float rotation on resident wellness and performance in the Duke University Eye Center Ophthalmology Residency Program.

Methods We analyzed three classes of ophthalmology residents: one class (n = 4) utilized the new night float rotation with no daytime clinical duties, while two senior classes (n = 12) utilized the traditional call system wherein they had daytime and nighttime responsibilities. Residents completed a questionnaire regarding their perceptions of the night float rotation. Supervising attendings (n = 15) were also surveyed about their perceptions of the …

Human M1 Macrophages Express Unique Innate Immune Response Genes After Mycobacterial Infection To Defend Against Tuberculosis, Arshad Khan, Kangling Zhang, Vipul K. Singh, Abhishek Mishra, Priyanka Kachroo, Tian Bing, Jong Hak Won, Eder Ledezma-Campos, Genesis P. Aguillón-Durán, Blanca I. Restrepo

School of Medicine Publications

Mycobacterium tuberculosis (Mtb) is responsible for approximately 1.5 million deaths each year. Though 10% of patients develop tuberculosis (TB) after infection, 90% of these infections are latent. Further, mice are nearly uniformly susceptible to Mtb but their M1-polarized macrophages (M1-MΦs) can inhibit Mtb in vitro, suggesting that M1-MΦs may be able to regulate anti-TB immunity. We sought to determine whether human MΦ heterogeneity contributes to TB immunity. Here we show that IFN-γ-programmed M1-MΦs degrade Mtb through increased expression of innate immunity regulatory genes (Inregs). In contrast, IL-4-programmed M2-polarized MΦs (M2-MΦs) are permissive for Mtb proliferation and exhibit reduced …

The Plasmodium Falciparum Abc Transporter Abci3 Confers Parasite Strain-Dependent Pleiotropic Antimalarial Drug Resistance, James M Murithi, Eva S Istvan, Daniel E Goldberg, Et Al.

2020-Current year OA Pubs

Widespread Plasmodium falciparum resistance to first-line antimalarials underscores the vital need to develop compounds with novel modes of action and identify new druggable targets. Here, we profile five compounds that potently inhibit P. falciparum asexual blood stages. Resistance selection studies with three carboxamide-containing compounds, confirmed by gene editing and conditional knockdowns, identify point mutations in the parasite transporter ABCI3 as the primary mediator of resistance. Selection studies with imidazopyridine or quinoline-carboxamide compounds also yield changes in ABCI3, this time through gene amplification. Imidazopyridine mode of action is attributed to inhibition of heme detoxification, as evidenced by cellular accumulation and heme …

Cutting Russia's Fossil Fuel Exports: Short-Term Economic Pain For Long-Term Environmental Gain, Maksym Chepeliev, Thomas Hertel, Dominique Van Der Mensbrugghe

Department of Agricultural Economics Faculty Publications

In response to the invasion of Ukraine, most OECD countries have announced punishing sanctions against Russia. In addition to targeting financial markets and service sectors, some countries have begun to impose restrictions on exports of Russia's fossil fuels. We analyse a scenario whereby most OECD countries put major restrictions on Russia's energy exports. The short-term implications are likely to be non-trivial for the EU – Russia's largest energy export destination. Households' real income could drop by 0.7 to 1.7 percent (relative to the reference case) with energy prices growing by as much as 11 percent. But in the longer run, …

The Researcher–Practitioner Symbiosis: Evolving Mutualisms From Parachutes, María Teresa Vargas, Máximo Garcia, Tito Vidaurre, Alex Carrasco, Natalia Araujo, Camille Medema, Nigel Asquith, Edwin Pynegar, Conrado Tobon, Yurani Manco, Zhao Ma, Jonathan Bauchet, Tara Grillos, Brooke Mcwherter

Department of Agricultural Economics Faculty Publications

Researchers and practitioners often exist symbiotically, but this relationship does not always benefit both parties. We here discuss a mutualistic research symbiosis that our organizations have developed over the last decade, the challenges which we have experienced as part of this process, and how our experiences may help others intending to develop such mutualisms. The defining characteristic of our model is that conservation implementers, not investigators, lead the research. This power balance has promoted synergies between researchers and practitioners and has resulted in one of the first ever Randomized Control Trials of a conservation intervention. We have shortened the distance …

Role Of Nk-Like Cd8+ T Cells During Asymptomatic Borrelia Burgdorferi Infection, Breanna M Scorza, Kurayi G Mahachi, Arin D Cox, Angela J Toepp, Danielle Pessoa-Pereira, Phyllis Tyrrell, Jesse Buch, Jennifer A Foltz, Dean Lee, Christine A Petersen

Open Access Publications

Lyme disease (LD) due to Borrelia burgdorferi is the most prevalent vector-borne disease in the United States. There is a poor understanding of how immunity contributes to bacterial control, pathology, or both during LD. Dogs in an area of endemicity were screened for B. burgdorferi and

Design Of Polar Materials Using Materials Informatics And First-Principles Calculations, Jon Okenfuss

McKelvey School of Engineering Graduate Student Theses & Dissertations

Polar materials have a dipole moment or polarization. Ferroelectrics are a special class of polar materials wherein the polarization can be switched with an external electric field. Because of their characteristics, ferroelectrics are especially useful in adjustable capacitors, non-volatile memories, and sensors. Materials databases like Materials Project contain a large number of materials, but identifying new metastable polar, and more specifically ferroelectric materials can be time consuming. In this project, we train a machine learning model to distinguish between binary compounds having a wurtzite structure—which have a permanent polarization—and their nonpolar zincblende and rock salt polymorphs. We use this model …

Source Of All Hair, Wearer Of All Socks, Samantha Modder

MFA in Visual Art

I work figuratively in pen, collage, and digital media to portray larger-than-life Black, female characters taking up space in real and imagined worlds. In a series of mural installations, I present a subjective Black woman’s fairytale to process interlocking structures of oppression. Centered in the speculative practice of the Black imaginary that creates spaces of both comfort and confrontation, I tell the story of a Black woman who escapes into an alternate reality made up of only herself, her hair, and the clothes she wears. This text is centered on a chapter of this ongoing narrative, Source of All Hair, …

Constants, Martin Lammert

MFA in Visual Art

A constant is something that I consider to be present in everything I make. Each overarching constant is a clue which may help the reader come to a conclusion about why I make sculpture. I will address repetitive motion in regard to failure and how this parallels the ongoing endeavors of the alchemist. I will discuss the idea of meaning as it exists in the conflict between cleanliness and the mess. I will explain how Hollywood movie tropes can be used to create sculpture. Lastly, I will frame the theatrical vessel as a vehicle to make a story more significant …

Echoed Sites And The Unknowable Object, Joseph Canizales

MFA in Visual Art

This thesis will discuss the expanded field of sculpture, simulacra, digital technology, and two terms I’ve devised: the unknowable object, and echoed sites. Within these two terms, I’m concerned with the complicated relationship between humans and geology and how we extract material from the ground without reflecting on the geologic history of the site. In echoed sites I create sculptures with and without a geologic site or object, by way of digital technology. These forms display two states paradoxically in balance, where what’s presented leaves more questions than answers. Thus, as part of echoed sites, exists the unknowable object. …

Disorientations, Noah Greene-Lowe

MFA in Visual Art

The materials that make up the ordinary and mundane in the United States also reinforce and normalize a white spatial imaginary. Conventions of mapping, imaging of land and landscape, and elements of the built environment continue to orient us in a logic of space as property. In my sculptural work, I employ strategies of disorientation and creative repair, or reconstruction, to unsettle the spatial practices of whiteness and structures of power embedded in the mundane, the familiar, and the domestic. I consider the planned cohousing community where I grew up as an influence on my work, and my whiteness. By …

Un Guisado: Allí, Allá And The Space In Between, Quinn A. Briceño

MFA in Visual Art

I am a Guisado: a savory stew. A blend of two worlds: one of Nicaragua, and the other of the United States. I am both Nicaragaüense y Estadounidense. As an artist, I work with painting and collage as a form of image making that carefully takes inspiration from those traditions to create a new narrative. In my work, I examine both my struggle with identity and how I came to be the person I am today. As I am both Nicaragüense and Estadounidense it is important that my paintings reflect those two worlds.

The ingredients making up my …

The Hidden Power Of Images: An Allegory Of Chaos And Performance In The Digital Age, Livia Xandersmith

MFA in Visual Art

Within this text, I explore the hidden power of images in American visual culture through painting-based installations. I investigate images of the past and present juxtaposed in a surrealist landscape. Through the use of images in the news, entertainment, advertising, and images within the home, I depict how the problems of the past bleed into our perceptions of the present. I find that this cycle of problem inheritance connects us as humans regardless of time, generation, and place. In my work, I explore the complexity of image culture and its shifting presence within the digital age. Using surrealist collage, I …

The Precarity Of Images: Sci-Fi Worldbuilding And Its Uses In Agitprop, Noah Jodice

MFA in Illustration & Visual Culture

“The Precarity of Images” examines how theories of worldbuilding common to the science fiction genre are applied to the making of agitational propaganda for liberation movements. In doing so, it questions how both explicit and implicit political images—posters, games, comics, illustrations, social media posts—either light a pathway for making a more just world or limit our ability to imagine alternate futures.

Following the ethos of Steven Jackson’s essay “Rethinking Repair,” the paper takes the “breakdown, erosion, and decay” of images as a starting point. Images change meaning over time as our cultural connections to them shift. Strategies of decoding and …

Fictitious Ecology, Paulina Zuckerman

MFA in Illustration & Visual Culture

My thesis project, The Mountain Fog, is a children’s picture book pitch that tells a light-hearted story of two dogs who must face an environmental disaster. In this accompanying critical essay, I break down the process of crafting a fictional relationship between author-illustrator, animal characters, and the environment. It begins through the context of J.R.R. Tolkien’s essay “On Fairy Stories,” which identifies seeing the world through two lenses - the Primary world and the Secondary world. From these terms, I navigate the idea of a fictitious ecology, an encapsulated anthropomorphic world governed by the creator’s personal experience with nature. This …

Superficial: An Exploration Of Decoration, Fashion, Taste, Camp, And Trends, Jillian Ohl

MFA in Illustration & Visual Culture

Since the rise of consumer culture in the late 19th century, Americans have had a complicated relationship with decorative objects, the idea of taste, and the cycle of trends within our classist society. This essay examines some of the decorative objects in my childhood home such as patterned wallpaper and an antique chair as well as a contemporary brand name mascara. While these objects do not have major functional properties, their decoration and superficiality bring me joy. To better understand my appreciation of decoration and aesthetics, I assess how an object or fashion is considered in good or bad taste. …

Meet Me In The Middle Ages: Engaging With Fantasy, Reality, And Collaborative World-Building, Amanda Greene

MFA in Illustration & Visual Culture

This critical essay accompanies and describes my thesis project, Medievalia Miscellany, a magazine for middle-grade readers which explores the world of medieval fantasy through art, comics, stories, and activities. Throughout the essay, I use my own term “archaeological upcycling” to discuss and explore a variety of relationships between ideas of parts and a whole. I then use it to characterize the way stories are created out of many different parts and how these parts help a reader to relate to both the world of the story and the world in which they live. I describe the genre of medieval fantasy …

X-Ray Observation Of The Roche-Lobe-Filling White Dwarf Plus Hot Subdwarf System Ztf J213056.71+442046.5, S. Mereghetti, N. La Palombara, T. Kupfer, T. R. Marsh, C. M. Copperwheat, K. Deshmukh, P. Esposito, T. Maccarone, F. Pintore, Liliana Rivera Sandoval

Physics & Astronomy Faculty Publications

ZTF J213056.71+442046.5 is the prototype of a small class of recently discovered compact binaries composed of a white dwarf and a hot subdwarf that fills its Roche lobe. Its orbital period of only 39 minutes is the shortest known for the objects in this class. Evidence for a high orbital inclination (i = 86°) and for the presence of an accretion disk has been inferred from a detailed modeling of its optical photometric and spectroscopic data. We report the results of an XMM-Newton observation carried out on 2021 January 7. ZTF J213056.71+442046.5 was clearly detected by the Optical Monitor, …

Belimumab For Systemic Lupus Erythematosus - Focus On Lupus Nephritis, Marlene Plüß, Silvia Piantoni, Björn Tampe, Alfred H J Kim, Peter Korsten

2020-Current year OA Pubs

In recent years, advances in the treatment and management of patients with systemic lupus erythematosus (SLE) have improved their life expectancy and quality of life. However, lupus nephritis (LN) still represents a major life-threatening complication of the disease. Belimumab (BEL), a fully human monoclonal IgG1λ antibody neutralizing soluble B cell activating factor, was approved more than ten years ago as add-on therapy in adults and pediatric patients with a highly active, autoantibody-positive disease despite standard of care (SoC). Recently, the superiority of the addition of BEL to SoC was also demonstrated in LN. In this review, we provide a comprehensive …

Transitioning From Traditional In-Person Studio-Based Education Of Apparel Design Courses To Online Education During The Covid-19 Pandemic, Divya Desai

LSU Doctoral Dissertations

Due to the COVID-19 pandemic and subsequent lockdowns many post-secondary educational institutions all-around the world, including the USA, were forced to transition their teaching methods from a traditional in-person to an online teaching format starting in the spring of 2020. This research however is focused on the transitioning of university-level studio-based Apparel Design (AD) courses to an online teaching format during the spring and fall 2020 semesters. Teaching AD courses that are studio-based and that particularly require hands-on skills like hand rendering, draping, sewing, or pattern drafting, are challenging to be taught online as they require in person step-by-step guidance …

Tuned In To Communication Sounds: Neuronal Sensitivity In The Túngara Frog Midbrain To Frequency Modulated Signals, Abhilash Ponnath, Michael J. Ryan, Zhide Fang, Hamilton E. Farris

School of Public Health Faculty Publications

For complex communication signals, it is often difficult to identify the information-bearing elements and their parameters necessary to elicit functional behavior. Consequently, it may be difficult to design stimuli that test how neurons contribute to communicative processing. For túngara frogs (Physalaemus pustulosus), however, previous behavioral testing with numerous stimuli showed that a particular frequency modulated (FM) transition in the male call is required to elicit phonotaxis and vocal responses. Modeled on such behavioral experiments, we used awake in vivo recordings of single units in the midbrain to determine if their excitation was biased to behaviorally important FM parameters. Comparisons of …

Because Potato, Candice Evers

MFA in Illustration & Visual Culture

This thesis project explores the phenomenological qualities of the internet; asking, since the internet is difficult to grasp, what other modes of investigation might we have available? Using an investigative framework set forth by Jack Halberstam, this thesis declines to come to knowledge solely through understanding the formal, the structural, the highly visible and mainstream. The literature that I have gathered provides a range of modes for interrogating the simultaneously central and inconsequential subject of my thesis itself: the potato. Juxtaposing the physical, political and material conditions of the potato the internet’s least academic mode of knowing: the meme. Analyzing …

“That’S What Hospice Is Supposed To Do”: How U.S. Hospice Care Staff Bridge Philosophy And Institutions, Morgan Alexa Leff

Senior Honors Papers / Undergraduate Theses

Hospice founder Cicely Saunders wrote that “the dignity and worth of each individual patient [are] central to Hospice philosophy—an idea closely tied to anthropological personhood (Saunders and Clark 2002). As dying in hospice becomes an increasing reality of life in the United States, we must grapple with how the ideals, costs, and challenges of hospice care play out in the healthcare system. The institutional structures meant to ensure a ‘good death’ (while protecting the interests of the state) can fracture care of the dying. As hospice staff work within and around these structures, they build meaning in care strategies that …

Breaking Boundaries: Investigating The Experiences Of Racially Diverse Low Socioeconomic Status Students Through A Narrative Inquiry Approach, Ryan Jumamil

Dissertations

Across the US, there is growing inequality of class distribution in predominately white and elite colleges and universities. Although gaining access to these institutions is typically the first hurdle, it is not the only challenge racially diverse low socioeconomic status (SES) students face. By investigating the college experiences of racially diverse low SES students enrolled in a predominately white elite institution, this study creates the foundation for an imperative discussion on the relationship between students' identity and attendance at predominately white elite institutions.

Through a Narrative Inquiry research approach and using semi-structured interviews as a data collection tool, two themes …

Editorial: The Dual-Use Dilemma For Biomimicry, Samar Damiati, Rami Mhanna, Shakil A. Awan, Rimantas Kodzius, Bernhard Schuster

School of Engineering, Computing and Mathematics

The biomimetic fabrication of 3D biology models confers design freedom across various applications. Taking inspiration from nature and using nature as a toolbox have helped in the production of effective and versatile tools that are integrated with modern technology principles and, importantly, perform quite similarly to natural living systems. Exploiting nature’s design principles can contribute to the improvement of the understanding and development of creative products in both fundamental research and industrial applications (Dicks, 2016; Orapiriyakul et al., 2018; Damiati, 2020). To address the significant heterogeneity among bio-inspired designs, this research topic collected articles that reflect the progress in the …

Modelling The Daily Electricity Demand Of Electric Vessels In Plymouth, L Ansell

School of Engineering, Computing and Mathematics

No abstract provided.

The Need To Belong: Interweaving State History In Adult Esl To Support Culturally Responsive Teaching, Sandra Watkins

Master's Projects and Capstones

As an increasing variety of cultures is represented in our adult ESL classrooms, and there is a growing need for instructors to employ culturally responsive teaching methods to bridge the gap between students’ cultural backgrounds and the current curriculum and instructional practices being used in our community college noncredit classrooms. The existing cultural dissonance between the mainstream culture and their own may cause learners to internalize negative individual and group identities resulting in low expectations for life changes. Without understanding the relationship between your home and your host country, the history of the new place, or a sense of connection …

Bridging Language Through Folktales And Authentic Outings: A Guidebook For Esl/Efl Teachers, Natalie Sauvain

Master's Projects and Capstones

There is a real need for authentic and culturally relevant materials to be integrated into ESL and EFL classrooms. Swiss classrooms, as well as the language acquisition curricula used in them, need to be redesigned with the native languages and culture of the learners’ in mind. All too often, teachers are dependent on textbooks, which can raise anxiety and decrease motivation among ELLs since the learners lack an authentic relationship with the teacher, language and materials. The aim of this field project is to address the lack of authentic materials in Swiss ESL classrooms. The creation of this field project …

Navigating School: An English As A Second Language Curriculum For Multilingual Caregivers, Kerry Stimpson

Master's Projects and Capstones

If multilingual families feel that they are not able to communicate with school staff, then these families may not become involved in their child’s school, and the child’s learning could be negatively impacted. The purpose of this project is to create a roadmap and lessons for English as a Second Language (ESL) instructors to implement in their classes with multilingual caregivers. This curriculum will address the lack of understanding that ESL teachers have in regard to the needs of multilingual caregivers to communicate with their child’s school staff and understand the school system in the United States. Given the content …