Digital Commons Network^™

Cdc6 Is Sequentially Regulated By Pp2a-Cdc55, Cdc14, And Sic1 For Origin Licensing In S. Cerevisiae, Jasmin Philip

Dissertations, Theses, and Capstone Projects

Control of DNA replication is critical for progression of the cell cycle and genomic stability. Cyclin-dependent kinases (CDKs) coordinate numerous phosphorylation events to accomplish two biological tasks for all living organisms: DNA replication and cell division. One CDK, Cyclin-Cdc28, is responsible for cell cycle progression in budding yeast. DNA replication requires a stepwise assembly of the pre-replicative complex on DNA, including Orc1-6, Cdc6, Cdt1 and Mcm2-7, during M-G1 phase. Cdc6 contains eight Cdc28 consensus sites, SP or TP motifs. Clb5-Cdc28 phosphorylates Cdc6-T7 to recruit Cks1, the Cdc28 phospho-adaptor, for subsequent multisite phosphorylation during S phase. There are two phospho-degrons at …

Falling Forward: The Governance Of School Reform, Race, And The Contest For A Dignified Future In Newark, N.J., Claire Cahen

Dissertations, Theses, and Capstone Projects

Following the Great Recession, a two-pronged policy agenda of charter school creation and public school austerity was implemented in many impoverished, multiracial urban school districts in the U.S. The reforms have yet to meet durably effective resistance. The three articles that comprise this dissertation address questions about how school reforms, austerity, and privatization have been made governable, specifically in relation to the: preservation of local Black political machine power, creation of a labor market for charter school teachers, ongoing contestation attempts by public educators in inert unions. These questions correspond to theoretical debates about contemporary forms of racism and the …

Outside The Boundaries Of Biomedicine: A Culture-Centered Approach To Female Patients Living Undiagnosed And Chronically Ill, Bianca Siegenthaler

USF Tampa Graduate Theses and Dissertations

As a community who voices feeling misunderstood, unheard, and uncared for by the medical system, female patients who live undiagnosed and chronically ill and their health narratives lie beyond biomedical boundaries. To examine how chronically ill and undiagnosed female patients narrate their experiences in and with the biomedical system and how these narratives resist biomedical health standards, I employ semi-structured interviews with 20 female patients living undiagnosed and chronically ill as well as engage in critical autoethnography to recount my own health experiences living a part of this community. In utilizing the culture-centered approach to health communication as a theoretical …

How Advances In Low-G Plumbing Enable Space Exploration, Mark M. Weislogel, John Graft, Andrew P. Wollman, Karl Cardin, Logan Torres, J. E. Goodman, J. C. Buchli

Mechanical and Materials Engineering Faculty Publications and Presentations

In many ways, plumbing is essential to life support. In fact, the advance of humankind on Earth is directly linked to the advance of clean, healthy, reliable plumbing solutions. Shouldn’t this also be true for the advancement of humankind in space? Unfortunately, the reliability of even the simplest plumbing element aboard spacecraft is rarely that of its terrestrial counterpart. This state of affairs is due entirely to the near-weightless “low-g” state of orbiting and coast spacecraft. But the combined passive capillary effects of surface tension, wetting, and system geometry in space can be exploited to replace the passive role of …

Wake Bifurcations Behind Two Circular Disks In Tandem Arrangement, Jianzhi Yang, Xiaowei Wu, Minghou Liu, Changjian Wang, Yuxin Wu, Zhihe Shen

Mechanical and Materials Engineering Faculty Publications and Presentations

The wake bifurcations behind two circular disks in tandem arrangement are investigated through numerical simulations. The separation distance between the disks, S/d, is chosen at 1, 2, 4, and 6, and the Reynolds number, Re, lies in the range of 100 Re 500. The wake dynamics are examined in terms of the flow structures as well as drag and lift coefficient characteristics. Seven main wake regimes are observed in the considered (Re, S/d) space: steady state (SS), Zig-zig (Zz) mode, standing wave mode, periodic state with reflectional symmetry breaking (RSB), periodic state with double-helical (DH) structures shedding, periodic state with …

The Relationship Between Voting Restrictions And Covid-19 Case And Mortality Rates Between Us Counties, Roman Pabayo, Erin Grinshteyn, Brian Steele, Peter Muennig, Sze Yan Liu

Department of Public Health Scholarship and Creative Works

Background

Since the 2010 election, the number of laws in the U.S. that create barriers to voting has increased dramatically. These laws may have spillover effects on population health by creating a disconnect between voter preferences and political representation, thereby limiting protective public health policies and funding. We examine whether voting restrictions are associated with county-level COVID-19 case and mortality rates.

Methods

To obtain information on restricted access to voting, we used the Cost of Voting Index (COVI), a state-level measure of barriers to voting during a U.S. election from 1996 to 2016. COVID-19 case and mortality rates were obtained …

Roger Williams University School Of Law Alumni Association Annual Breakfast & Meeting June 23, 2022, Roger Williams University School Of Law

School of Law Conferences, Lectures & Events

No abstract provided.

From The Steppe To The Stars: National Space Legislation In Central Asia In 2021, Christian A. Packard

Journal of Space Law

No abstract provided.

Front Matter, Journal Editors

Journal of Space Law

Includes table of contents.

From The Editor, Michelle L. D. Hanlon

Journal of Space Law

No abstract provided.

Interrupted Broadcasts? The Law Of Neutrality And Communications Satellites, Joshua J. Wolff

Journal of Space Law

No abstract provided.

The Principle Of “Harmful Contamination” Applied To Human Missions To Mars, Melissa De Zwart, Stacey Henderson, Rachel Neef

Journal of Space Law

No abstract provided.

From The Creation Of The Euspa To A New U.N. Agency To Coordinate Gnss-Eo-Telecommunication Systems, Ivan Fino

Journal of Space Law

No abstract provided.

The Role Of Customary International Law In Future Lunar Activities, Nivedita Raju, Héloïse Vertadier

Journal of Space Law

No abstract provided.

From Goldeneye To Landsat-7: Combatting Cyber Intrusions To Space-Based Satellite Systems Utilizing International Law, Andrew Fois

Journal of Space Law

No abstract provided.

The Time Is Now: How The United States Can Lead Active Debris Removal Efforts, Denton Hunter, Quinn Mckemey

Journal of Space Law

No abstract provided.

Identification Of Shared And Disease-Specific Host Gene–Microbiome Associations Across Human Diseases Using Multi-Omic Integration, Sambhawa Priya, Michael B. Burns, Tonya Ward, Ruben A.T. Mars, Beth Adamowicz, Eric F. Lock, Purna C. Kashyap, Dan Knights, Ran Blekhman

Biology: Faculty Publications and Other Works

While gut microbiome and host gene regulation independently contribute to gastrointestinal disorders, it is unclear how the two may interact to influence host pathophysiology. Here we developed a machine learning-based framework to jointly analyse paired host transcriptomic (n = 208) and gut microbiome (n = 208) profiles from colonic mucosal samples of patients with colorectal cancer, inflammatory bowel disease and irritable bowel syndrome. We identified associations between gut microbes and host genes that depict shared as well as disease-specific patterns. We found that a common set of host genes and pathways implicated in gastrointestinal inflammation, gut barrier protection and energy …

A Labeled Dataset For Investigating Cyberbullying Content Patterns In Instagram, Mara Hamlett, Grace Powell, Yasin N. Silva, Deborah Hall

Computer Science: Faculty Publications and Other Works

As online communication continues to become more prevalent, instances of cyberbullying have also become more common, particularly on social media sites. Previous research in this area has studied cyberbullying outcomes, predictors of cyberbullying victimization/perpetration, and computational detection models that rely on labeled datasets to identify the underlying patterns. However, there is a dearth of work examining the content of what is said when cyberbullying occurs and most of the available datasets include only basic labels (cyberbullying or not). This paper presents an annotated Instagram dataset with detailed labels about key cyberbullying properties, such as the content type, purpose, directionality, and …

Phishing For Fun, Madeline Moran, Anna Hart, Loretta Stalans, Eric Chan-Tin, Shelia Kennison

Computer Science: Faculty Publications and Other Works

Perform a phishing experiment to see how many people fall victim. This study was approved by the Loyola IRB

A Physico-Chemical Contribution To The Conventional Technique Of Preparation Graphene Oxide, Zainab Abd, Nasser Habib, Abbas Khammas

Journal of Applied Sciences and Nanotechnology

The modified Graphene Oxide (GO) synthesis methods used over the past sixty years is contributed mainly to improving its characteristics and increasing its advanced applications. Therefore, in this work, modifying Hummer’s Method via oxidizing graphite flakes using one type of acid (H2SO4) was performed without any chemical agents. Also, ultra-sonication and filtration were implemented with optimal parameters (50 kHz frequency during 120 minutes at room temperature 30 oC) to prepare GO nanosheets. These procedures improved GO characteristics via analyzing; Particle size, X-ray diffraction pattern (XRD), Ultra-violet visible (UV-vis) absorption, and Scanning Electron Microscopy (SEM). The obtained results showed that the …

Comparison Of Performance Of Self-Expanding And Balloon-Expandable Transcatheter Aortic Valves, Hoda Hatoum, Milad Samaee, Janarthanan Sathananthan, Stephanie Sellers, Maximilian Kuetting, Scott M. Lilly, Abdul R. Ihdayhid, Philipp Blanke, Jonathon Leipsic, Vinod H. Thourani, Lakshmi Prasad Dasi

Michigan Tech Publications, Part 1

Objective: To evaluate the flow dynamics of self-expanding and balloon-expandable transcatheter aortic valves pertaining to turbulence and pressure recovery. Transcatheter aortic valves are characterized by different designs that have different valve performance and outcomes. Methods: Assessment of transcatheter aortic valves was performed using self-expanding devices (26-mm Evolut [Medtronic], 23-mm Allegra [New Valve Technologies], and small Acurate neo [Boston Scientific]) and a balloon-expandable device (23-mm Sapien 3 [Edwards Lifesciences]). Particle image velocimetry assessed the flow downstream. A Millar catheter was used for pressure recovery calculation. Velocity, Reynolds shear stresses, viscous shear stress, and pressure gradients were calculated. Results: The maximal velocity …

Relationship Between Course Placement Criteria And Mathematics Achievement In An All-Boys Catholic School, Daniel J. Mccue

Journal of Catholic Education

This study explored the mathematics course placement process for incoming students in an all-boys Catholic high school. The sequential nature of mathematics significantly impacts students’ opportunity to learn; moreover, the mathematics course taken by a student during ninth grade can have far-reaching effects. Previous studies have found that ninth-grade students enrolled in Geometry, rather than Algebra 1, have a greater chance of completing advanced mathematics courses and experiencing increased mathematics success. Thus, adequately prepared students should be placed in Geometry whenever possible. To aid this effort, this study investigated whether a relationship exists between course placement criteria and future mathematics …

A Phenomenology Of The Job-Related Experiences Of Early Career Catholic Elementary School Principals, Sarah K. Kerins, Lucinda Spaulding

Journal of Catholic Education

This qualitative phenomenology investigated the job-related experiences of early career Catholic elementary school principals (N = 13) in the Mideastern region of the United States. Data were collected from an introductory survey, semi-structured interviews, two focus groups, and a participant designed plan for professional development. The findings indicated that Catholic elementary principals in their early career are motivated by a calling to a vocation in Catholic school leadership as well as the ability to develop and implement a vision for their school. Principals reported being challenged by limited resources, balancing the demands of the position, and navigating relationships. Finally, principals …

Views Of Catholic Middle School Students On Handling Peer Aggression, Ishita Khemka, Linda Hickson, Lina Gilic

Journal of Catholic Education

Peer aggression toward peers who are perceived as weaker or different is a widespread problem for middle-school students including those attending Catholic middle schools. Middle school students’ normative beliefs about the acceptability of various types of aggressive behavior influences their own potential involvement in bullying or as bystanders to bullying in school environments. This study examined decision-making preferences of 6^th, 7^th, and 8^th grade girls and boys for how they thought a targeted peer (from a vulnerable group) should handle a situation of physical, verbal, or cyber aggression. Significant gender, grade and type of peer …

The Potential Of Catholic Schools: Public Virtues Through Private Voucher, Joseph Prud'homme

Journal of Catholic Education

Recent US Supreme Court cases signal a likely increase in calls for K-12 school choice programs that include the option of enrolling in religious schools. In turn, criticism of religious school-inclusive school choice programming is likely to shift to policy and values-based critiques. This article addresses two allegations of Catholic primary and secondary school deficiencies in achieving objectives important to a pluralist society, allegations that would invalidate indirect state support of Catholic schools. By analyzing the aesthetics of Hans Georg Gadamer and Aristotelian moral theory in light of American Catholic schools’ potential, this paper rejects claims that Catholic education is …

On The Catholic Identity Of Students And Schools: Value Propositions For Catholic Education, Daniel Lapsley, Katheryn Kelley

Journal of Catholic Education

The Catholic school sector is under significant stress with declining enrollments and schools closing in virtually every diocese in the United States. This paper examines two value propositions for Catholic education. One is its role in providing foundational support for the development of personal spiritual identity in emerging adulthood and across the lifecourse. The second is the contribution of Catholic education to moral-character formation. Both propositions are relatively underdeveloped. The question of students’ personal spiritual identity is overshadowed by the understandable concern with the Catholic identity of schools. The question of moral-character formation is subsumed by catechesis and liturgy but …

Beyond Academic Performance And Faith Formation: A Focus Section On Values And The Future Of Catholic Schools In The United States, Quentin Wodon

Journal of Catholic Education

Readers of the JCE are likely familiar with the enrollment crisis in K–12 Catholic schools in the United States. In 1965, 5.2 million children were enrolled in close to 13,000 Catholic schools. Today, 1.7 million children are enrolled in fewer than 6,000 schools (National Catholic Educational Association, 2022). The future does not look particularly promising. The reduction in the number of students due to lower fertility rates (National Center for Education Statistics, 2022) and a decline in the share of the adult population who are religiously affiliated (Smith, 2021) are sources of concerns. What might be done to stem the …

The School To Family Pipeline: What Do Religious, Private, And Public Schooling Have To Do With Family Formation?, Patrick J. Wolf, Albert Cheng, Wendy Wang, W. Bradford Wilcox

Journal of Catholic Education

Private religious schools are widely seen as value-laden communities that mold the character of their students. Thus, we expect adults who attended religious schools as children to demonstrate more favorable family outcomes related to stable marriages and childbearing. We further expect Protestant schooling to have a more powerful effect on marital outcomes than Catholic schooling, given the heavier focus of Protestantism on marriage. Finally, we expect stronger positive associations between religious schooling and marital outcomes for adults who grew up in difficult circumstances compared to adults who grew up in advantaged circumstances. We test these hypotheses using survey data from …

Glider Gladiators: American Transport Aviators And Glidermen In World War Ii, Gregory Franklin Withrow

History Theses, Dissertations, and Student Creative Activity

Examining the development and employment of gliderborne troops and paratroopers of World War II demonstrates marked differences between their inception and evolution among the Germans, British, and Americans. While Germany led in training and deploying such troops, their usage declined rapidly after the disastrous invasion of Crete. Early advancements in German-glider applications emanated primarily from post-World War I restrictions upon powered military aircraft development. This fact, juxtaposed with accelerated Allied soldier training and development of airborne troop doctrine while World War II progressed, proves a stark dichotomy of intra-war strategic evolution. Yet, among the Allies no total consensus in specifics …

Outcomes And Return-To-Sport Rates For Elite Athletes With Femoral Retroversion Undergoing Hip Arthroscopy: A Propensity-Matched Analysis With Minimum 2-Year Follow-Up, Jade S Owens, Andrew E Jimenez, Michael S Lee, David R Maldonado, Ajay C Lall, Benjamin G Domb

Faculty, Staff and Student Publications

BACKGROUND: Return to sports (RTS) and patient-reported outcomes (PROs) for elite athletes with femoral version abnormalities undergoing hip arthroscopy have not been well established.

PURPOSES: To (1) report minimum 2-year PROs and RTS rates in elite athletes with femoral retroversion who underwent primary hip arthroscopy and (2) compare clinical results to those of a propensity-matched control group of elite athletes with normal femoral version who underwent primary hip arthroscopy.

STUDY DESIGN: Cohort study; Level of evidence, 3.

METHODS: Data were prospectively collected and retrospectively reviewed for elite (professional and collegiate) athletes with femoral version1, hip dysplasia, and previous ipsilateral hip …