Digital Commons Network^™

The Dna Methylation Landscape Of Five Pediatric-Tumor Types, Alyssa C. Parker, Badí I. Quinteros, Stephen Piccolo

Faculty Publications

Fewer DNA mutations have been identified in pediatric tumors than in adult tumors, suggesting that alternative tumorigenic mechanisms, including aberrant DNA methylation, may play a prominent role. In one epigenetic process of regulating gene expression, methyl groups are attached at the 5-carbon of the cytosine ring, leading to 5-methylcytosine (5mC). In somatic cells, 5mC occurs mostly in CpG islands, which are often within promoter regions. In Wilms tumors and acute myeloid leukemias, increased levels of epigenetic silencing have been associated with worse patient outcomes. However, to date, researchers have studied methylation primarily in adult tumors and for specific genes—but not …

Mpc-Stanet: Alzheimer’S Disease Recognition Method Based On Multiple Phantom Convolution And Spatial Transformation Attention Mechanism, Yujian Liu, Kun Tang, Weiwei Cai, Aibin Chen, Guoxiong Zhou, Liujun Li, Runmin Liu

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Alzheimer's disease (AD) is a progressive neurodegenerative disease with insidious and irreversible onset. The recognition of the disease stage of AD and the administration of effective interventional treatment are important to slow down and control the progression of the disease. However, due to the unbalanced distribution of the acquired data volume, the problem that the features change inconspicuously in different disease stages of AD, and the scattered and narrow areas of the feature areas (hippocampal region, medial temporal lobe, etc.), the effective recognition of AD remains a critical unmet need. Therefore, we first employ class-balancing operation using data expansion and …

Mpc-Stanet: Alzheimer’S Disease Recognition Method Based On Multiple Phantom Convolution And Spatial Transformation Attention Mechanism, Yujian Liu, Kun Tang, Weiwei Cai, Aibin Chen, Guoxiong Zhou, Liujun Li, Runmin Liu

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Alzheimer's disease (AD) is a progressive neurodegenerative disease with insidious and irreversible onset. The recognition of the disease stage of AD and the administration of effective interventional treatment are important to slow down and control the progression of the disease. However, due to the unbalanced distribution of the acquired data volume, the problem that the features change inconspicuously in different disease stages of AD, and the scattered and narrow areas of the feature areas (hippocampal region, medial temporal lobe, etc.), the effective recognition of AD remains a critical unmet need. Therefore, we first employ class-balancing operation using data expansion and …

Department Of Hous. Preserv. & Dev. Of The City Of N.Y. V. Rosenfeld

All Decisions

No abstract provided.

Valsac 908 Llc V. Crespo

All Decisions

Grants motion to vacate ERAP stay in a super holdover finding that the super never paid rent and, given plain meaning to the language of the statute, that the super does not meet the definition of "a person, other than a tenant or a member of a tenant's immediate family, occupying a premises with the consent of the tenant or tenants."

Assessment Of Information And Communication Technology Skills In Operation And Service Delivery By Para Professionals Of University Of Jos Library., David Dirmun Dimlong, Onyeke Emmanuel Onyeke, Christopher Obigho Uwagwe, Gushop Sintiki Gideon

Library Philosophy and Practice (e-journal)

In this research work “Assessment of Information and Communication Technology Skills in Operation and Service Delivery by Para Professionals of University of Jos Library” is to assess the information and communication technology skills in operation and service delivery by para professionals of University of Jos Library. The objective is to-find out the type of Information and Communication Technology resources available for use by para professional staff in the library; to ascertain the level of understanding of Information Communication Technology by the para professionals in the library; to assess the level of utilization of the Information Communication Technology skills acquired by …

Antibody-Mediated Lilrb2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells To Kill Mycobacterium Tuberculosis, Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, Shu-Hsia Chen

School of Medicine Publications

Tuberculosis is a leading cause of death in mankind due to infectious agents, and Mycobacterium tuberculosis (Mtb) infects and survives in macrophages (MФs). Although MФs are a major niche, myeloid-derived suppressor cells (MDSCs) are an alternative site for pathogen persistence. Both MФs and MDSCs express varying levels of leukocyte immunoglobulin-like receptor B (LILRB), which regulate the myeloid cell suppressive function. Herein, we demonstrate that antagonism of LILRB2 by a monoclonal antibody (mab) induced a switch of human MDSCs towards an M1-macrophage phenotype, increasing the killing of intracellular Mtb. Mab-mediated antagonism of LILRB2 alone and its combination with a pharmacological blockade …

Soft-Mask De-Mixing For Anechoic Mixtures, Swarnadeep Bagchi, Ruairí De Fréin

Articles

This paper extends a computationally efficient, soft-mask based source separation (SS) technique called Redress, to anechoic mixing scenarios. SS methods are an integral part of hearing aid research. We call the resulting method D-Redress. In its original form, Redress was intended for instantaneous mixing scenarios. Numerical evaluations demonstrate that soft-mask based techniques reduce the level of artifacts in the separated speech. Monte Carlo trials on 1000 real speech mixtures demonstrate that the D-Redress successfully extends Redress in terms of Overall-Perceptual (OPS), Target-Perceptual (TPS) scores and Human-Ear Intelligibility (HEI).

Osm-Gan: Using Generative Adversarial Networks For Detecting Change In High-Resolution Spatial Images, Lasith Niroshan, James Carswell

Articles

Detecting changes to built environment objects such as buildings/roads/etc. in aerial/satellite (spatial) imagery is necessary to keep online maps and various value-added LBS applications up-to-date. However, recognising such changes automatically is not a trivial task, and there are many different approaches to this problem in the literature. This paper proposes an automated end-to-end workflow to address this problem by combining OpenStreetMap (OSM) vectors of building footprints with a machine learning Generative Adversarial Network (GAN) model - where two neural networks compete to become more accurate at predicting changes to building objects in spatial imagery. Notably, our proposed OSM-GAN architecture achieved …

Pluteus Insidiosus Complex, Four New Species Described And Pluteus Reisneri Resurrected, Hana Ševčíková, Giuliano Ferisin, Ekaterina Malysheva, Alfredo Justo, Jacob Heilmann-Clausen, Egon Horak, Lyudmila Kalinina, Oğuzhan Kaygusuz, Henning Knudsen, Nelson Menolli, Pierre-Arthur Moreau, Guillermo Muñoz González, Irja Saar, İbrahim Türkekul, Francesco Dovana

Faculty, Staff and Students Publications

We studied the taxonomy of Pluteus insidiosus and similar species using morphological and molecular (nrITS, TEF1-α) data, including a detailed study of the type collection of P. insidiosus. Based on our results, we recognize five species in this group: P. insidiosus sensu stricto and four other taxa: P. assimilatus; P. farensis; P. flavostipitatus; and P. pseudoinsidiosus; described here as new. All these taxa are distinct from each other based on molecular data, but some of them are semi-cryptic based on morphology and co-occur in the Palaearctic region. An additional molecular lineage, phylogenetically separates from the P. …

Systemic Ablation Of Camkk2 Impairs Metastatic Colonization And Improves Insulin Sensitivity In Tramp Mice: Evidence For Cancer Cell-Extrinsic Camkk2 Functions In Prostate Cancer, Thomas L Pulliam, Dominik Awad, Jenny J Han, Mollianne M Murray, Jeffrey J Ackroyd, Pavithr Goli, Jonathan S Oakhill, John W Scott, Michael M Ittmann, Daniel E Frigo

Faculty, Staff and Students Publications

Despite early studies linking calcium-calmodulin protein kinase kinase 2 (CAMKK2) to prostate cancer cell migration and invasion, the role of CAMKK2 in metastasis in vivo remains unclear. Moreover, while CAMKK2 is known to regulate systemic metabolism, whether CAMKK2's effects on whole-body metabolism would impact prostate cancer progression and/or related comorbidities is not known. Here, we demonstrate that germline ablation of

Fort Hays State University Tiger Weekly, June 10, 2022, University Relations

Tiger Weekly Newsletters

No abstract provided.

Artemisia Gentileschi: A Deeper Look Into Burghley House Susanna, Emma M. Rochlin

University Honors Theses

In this article Emma Rochlin investigates the debated topic amongst art historians regarding Artemisia Gentileschi's Susanna and the Elders of 1622. References to the research of Mary Garrard, stated in her book Artemisia Gentileschi Around 1622 encouraged this discussion. Rochlin examines expressions, landscapes, and signatures while referencing other paintings during this period of Gentileschi's career, along with the discoveries of Garrard, in order to decipher the authenticity of this painting.

Honey Tree: A Neo-Soul Album, Artist & Musical Development Through The Electronic Press Kit, Raine Welterlen

University Honors Theses

This paper describes the process of preparing a Neo-Soul album for public release including monetization, marketing, arrangement, and production.

Understanding The Efficacy Of Telehealth In Pediatric Occupational Therapy, Katheren Bettermann

University Honors Theses

In response to the COVID-19 pandemic, the American Occupational Therapy Association (AOTA) expanded telehealth, an electronic health care service, to virtually treat patients. Many occupational therapy and public health scholars are researching the effectiveness of telehealth for all age groups or for adults only. The purpose of this study is to understand the efficacy of telehealth as a pediatric occupational therapy modality and expose variables effecting treatment quality.

I created a survey in Qualtrics, a web-based software. The target population was pediatric occupational therapists (OTs) licensed in Oregon. Qualitative and quantitative questions addressed respondent qualifications, telehealth and pediatric occupational therapy …

Maternal And Fetal Bile Acid Homeostasis Regulated By Sulfated Progesterone Metabolites Through Fxr Signaling Pathway In A Pregnant Sow Model, Peng Wang, Peiqiang Yuan, Sen Lin, Heju Zhong, Xiaoling Zhang, Yong Zhuo, Jian Li, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, De Wu, Douglas G Burrin, Zhengfeng Fang

Faculty, Staff and Students Publications

Abnormally elevated circulating bile acids (BA) during pregnancy endanger fetal survival and offspring health; however, the pathology and underlying mechanisms are poorly understood. A total of nineteen pregnant sows were randomly assigned to day 60 of gestation, day 90 of gestation (G60, G90), and the farrowing day (L0), to investigate the intercorrelation of reproductive hormone, including estradiol, progesterone and sulfated progesterone metabolites (PMSs), and BA in the peripheral blood of mother and fetuses during pregnancy. All data were analyzed by Student’s t-test or one-way ANOVA of GraphPad Prism and further compared by using the Student–Newman–Keuls test. Correlation analysis was …

Intersecting Mobilities: Beyond The Autonomy Of Movement And Power Of Place, Miriam Ticktin, Rafi Youatt

Publications and Research

It is widely understood that we live in a world where people, goods, species, and things of all sorts are on the move, and that the politics around mobility and its regulation and meaning are critical to contemporary political and social life. Human migration has been globally intensive for well over a century; industrial economic production, consumption, and trade move goods around the world; transportation infrastructure moves all sorts of cargo around, human and nonhuman; regular and irregular ecological processes and changes are creating new patterns of nonhuman movement; variants of viruses race around the world; even geological elements are …

Borders: A Story Of Political Imagination, Miriam Ticktin

Publications and Research

This article traces three different political imaginaries about borders, suggesting that the dominant imaginary—the one of border walls, driven by a fear of invasion—is only one way to live in the world. The goal is to make space in our political imaginations to rethink how we live together, including thinking beyond nation-states as containers that keep people in or out. By first showing how the vision of invasion is built and maintained with intersecting transnational technologies and ideologies, I open the way to thinking otherwise. Second, I trace the counterpolitics of borders developed by artists and activists, resisting borders and …

Contribution Of A Differentiated Counseling Program Based On Self-Organization And Goal Orientation In Improving The Level Of Scientific Flow And Self-Awareness Among Economically Disadvantaged Gifted Students, Refah M. Al-Johar, Abdulhamid A. Al-Arfaj

International Journal for Research in Education

The current study aimed to improve the level of scientific flow level and self-awareness of economically disadvantaged gifted students through an online counseling program that depends mainly on self-organization and goal orientation. The study used a mixed-methods design. The sample consisted of 6 gifted economically disadvantaged students; 3 middle school students and 3 secondary school students. The authors developed the scientific flow scale and the self-awareness scale. Moreover, a differentiated counseling program was developed. The results have shown statistically significant differences (α < 0.01) on the scientific flow scale in favor of the post-testing. The results also showed statistically significant differences at the level of (α < 0.01) on the self-awareness scale in favor of the post-testing, which indicates the effect of the counseling program. The study also identified the factors affecting the nature of the relationship between economic deprivation, self-regulation, and goal orientation by determining the impact of economic deprivation on talent aspects, then determining the influencing factors. Data analysis revealed that there are three influential factors, namely the degree of economic deprivation, age, and the level of family education. The role of the counseling program in reducing the effectiveness of the factors affecting the nature of the relationship between economic deprivation, self-regulation and goal orientation was analyzed.

Keywords: Program, differentiated counseling, self-organization, goals orientation, scientific flow, self-awareness, gifted students, economically disadvantaged.

The Effectiveness Of Augmented Virtual Reality Applications On Developing Non-Verbal Social Communication For Pre-School Children With Autism Spectrum Disorder In The State Of Qatar, Mohamed S. Hamid, Maiada Saad Al-Namroti, Fatima Mubarak Al-Sulaiti, Garfh Salim Alhader

International Journal for Research in Education

The current research aimed to design simple application software based on augmented reality (AR) technology, which may contribute to the development of some of the non-verbal communication skills in a sample of 20 children with an autism spectrum disorder, aged between 5 and six years in the state of Qatar. The study used a questionnaire to measure the current non-verbal social skills designed by researchers, in addition to developing some AR applications on tablets. The study followed a quasi-experimental approach based on one experimental group with a pre-and-post design. Some non-parametric statistical methods were used. The proposed application is expected …

The Impact Of Community Support During Covid-19 In Meeting Needs, Developing Academic Commitment And Volunteer Values Among Gifted Students At The Intermediate Stage In Poor Environments, Alaa Eldin Abdel Hamid Ayoub, Helmy Mohamed Elfiel

International Journal for Research in Education

The current research aimed at developing a program based on community support and assessing its impact during the covid-19 pandemic in meeting needs, developing academic commitment and volunteering values among gifted students in the intermediate stage in poor environments. The quasi-experimental method was used for the experimental and control groups. The sample consisted of 41 gifted students (21 experimental group, 20 control group) and the experimental group underwent a community support program that lasted for 14 weeks. Measures of academic needs, academic commitment, and volunteer values were administered before starting and after completing the program. The results revealed that there …

Parenting Practices In Inculcating The Values Of Volunteering Among The Children Of The Emirate Of Sharjah, Ali Ahmad Al-Barakat

International Journal for Research in Education

The current study aimed at investigating the practices of parental education in inculcating the values of volunteer work among the children of the Emirate of Sharjah. To achieve the aims of the study, a sample of 76 parents was selected from the Emirate of Sharjah during the second academic semester 2020/2021. The study data were collected through the qualitative research methodology using a semi-structured interview. An interview schedule was prepared, and its validity and reliability were verified. Based on the qualitative research procedures, the data were analyzed by the grounded theory approach. The findings of the study showed a set …

Hope And Wonder In The Wasteland: Post-Apocalyptic Fiction As Tolkienian Fairy Story, Alfredo J. Mac Laughlin

Journal of Tolkien Research

J. R. R. Tolkien’s four functions of fantasy stories, as developed in his Andrew Lang lecture “On Fairy Stories” (1939), have become a key conceptual tool for discussing human beings’ attraction to fantasy stories, particularly when attempting to push the analysis beyond the literary into the aesthetic, and beyond the aesthetic into the existential. Applying this interpretive key to an analysis of the expanding genre of post-apocalyptic fiction reveals that post-apocalyptic stories, despite superficial differences, are surprisingly close to fairy stories in their aesthetic core and orientation, and that post-apocalyptic stories are well-suited to fulfill—albeit with their own distinctive aesthetic …

The Rapid Transition From Face-To-Face To Online Education Due To Covid-19: Observations Of Higher Education Faculty In Texas, Bill Mchenry, Kevin Williams, Ellen Melton

TxDLA Journal of Digital Learning

The COVID-19 pandemic has made a profound impact on education on a global scale. Disruptions and changes in modalities in the delivery of education, both in higher education and pk12 environments, have potentially forever changed the expectations of education systems. This study discusses the rapid transition to online education due to the pandemic from the lenses of higher education faculty in Texas.

Measuring Shuttlecock Drag In Free Flight, Achyut Paudel, Lloyd Smith

International Sports Engineering Association – Engineering of Sport

No abstract provided.

Body-Attached Sensor Nodes For Automatic Detection Of Hike Events And Parameters, Giuseppe Sanseverino, Dominik Krumm, Wolfgang Kilian, Stephan Odenwald

International Sports Engineering Association – Engineering of Sport

No abstract provided.

Variability In Rotational Traction Testing Of Artificial Surfaces., Harry Mcgowan, Paul Fleming, Steph Forrester, David James

International Sports Engineering Association – Engineering of Sport

No abstract provided.

Improvement Of The Training Paddle For A Swimmer With Unilateral Transradial Deficiency, Motomu Nakashima, Yohei Chida

International Sports Engineering Association – Engineering of Sport

No abstract provided.

The Effect Of Pressure And Kick Speed In Soccer On Head Injury And Goalkeeper Movement, Praveen Kumar Sharma, Lloyd Smith

International Sports Engineering Association – Engineering of Sport

No abstract provided.

A Novel Framework For Design-Property Decision-Making In Polymer Lattices When Controlling For Printed Mass, Ana Paula Clares, Guha Manogharan, Landon Thomas, David Krzeminski

International Sports Engineering Association – Engineering of Sport

No abstract provided.