Digital Commons Network^™

My Journey To Positivity And Its Influence On Creativity And Education, Jennifer P. Youngblood

Creativity and Change Leadership Graduate Student Master's Projects

This project is about positivity and its impact on education and creativity. This Master's Project in Creative and Change Leadership is aimed to investigate, comprehend, and apply positively in the fields of creativity and learning. Our learning and creativity suffer when we lack positivity. One may even argue that without positivity, our lives deteriorate. My objective is to cultivate positivity in both my personal and professional lives, thus transforming myself into an unconsciously talented individual.

2022-August-01-Calling Etsu Choirs Alumni, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – East Tennessee State University has issued a call to alumni of the ETSU Choirs to gather for a special reunion concert. 

The event, which will help kick off Homecoming week at ETSU, happens at 7:30 p.m. on Saturday, Oct. 15, in the ETSU Martin Center for the Arts. 

Greyscale will be honored at concert

“We are inviting all eras of the ETSU Choirs to come together for what will be a truly special evening,” said Dr. Alan Stevens, director of choral activities and chair of the Department of Music.  

ETSU is home to many award-winning …

2022-August-01-New Etsu Faculty - Part 1 - Bucwire, University Marketing And Communication, East Tennessee State University

ETSU News

Leendert Craig

Lecturer

Department of Engineering, Engineering Technology, Surveying, and Interior Architecture
College of Business and Technology

What are you looking forward to the most about being an ETSU faculty member?

I am looking forward to learning all I can from my fellow faculty members and working with the students. I think it is fun to watch them grow as they learn.

Where were you most recently working?

Last year I was working as an adjunct at ETSU.

What are your favorite hobbies?

My favorite hobby is learning. I love taking things apart to learn their secrets and finding ways …

The Impact And Spillover Effects Of Hiv Self-Test Technology On Hiv Outcomes Of The South African Working Class, Cyprian Mostert

Brain and Mind Institute

Background: South Africa recently adopted HIV self-test technology (HIVST) to improve HIV testing and encourage earlier treatment initiation in working populations with a low uptake of conventional testing approaches. This study investigates the impact of HIVST on testing outcomes, focusing on both frequent and infrequent working-class testers. The paper also examines the spillover effect of HIVST on antiretroviral (ART) treatment initiation. To identify these effects, the author focused on South Africa and exploited the HIVST distribution data of 6259 beneficiaries of HIVST.

Methods: The author used a two-stage least-squared model to quantify the impact of the HIVST on …

Human-Centered Design Exploration With Kenyan Health Workers On Proposed Digital Mental Health Screening And Intervention Training Development: Thematic Analysis Of User Preferences And Needs, Manasi Kumar, Paul Macharia, Vincent Nyongesa, Joseph Kathono, Obadia Yator, Shillah Mwaniga, Mary Mckay, Keng Yen Huang, Rahul Shidhaye, Simon Njuguna

Brain and Mind Institute

Background: Health providers' perceived sense of knowledge, competency, and self-efficacy to support the needs of their patients contributes to optimal patient health outcomes. With regards to mental health service delivery in Kenya, this area needs further exploration. Guided by the e-health technology acceptance mode, the needs and preferences of health care providers around mental health training for clinical management and their ability to intervene in peripartum adolescent mental health care are explored. We probed how well-equipped service providers are, their engagement with technology to learn and offer services. The health care provider's technology use preferences were also explored.

Method: Guided …

A Computational Model Of The Line-1 Retrotransposon Life Cycle And Visualization Of Metabolic Networks In 3-Dimensions., Michael D. Martin

Electronic Theses and Dissertations

Computational modeling of metabolic reactions and cellular systems is evolving as a tool for quantitative prediction of metabolic parameters and reaction pathway analysis. In this work, the basics of computational cell biology are presented as well as a summary of physical processes within the cell, and the algorithmic methods used to find time dependent solutions. Protein-protein and enzyme-substrate interactions are mathematically represented via mass action kinetics to construct sets of linear differential equations that describe reaction rates and formation of protein complexes. Using mass action methods, examples of reaction networks and their solutions are presented within the Virtual Cell simulation …

Effects Of Monovalent And Divalent Ions In Factor Xiii Activation And Crosslinking., Richard Laporca Lumata

Electronic Theses and Dissertations

Factor XIII (FXIII) is an emerging target for treating blood clotting and cardiovascular related diseases. FXIII can be activated non-proteolytically by the presence of elevated Ca²⁺ levels (2-100 mM) or proteolytically by thrombin-cleavage of the Activation Peptide along with low mM Ca²⁺. The studies herein utilized fluorescence to examine how monovalent and divalent ions influence the transglutaminase activity and conformation of FXIII. Monodansylcadaverine assays revealed that increasing ionic radius (Cs⁺ > K⁺ > Na⁺ > Li⁺) and increasing ionic strength (XCl^- levels and SO₄^2- > Cl^-) elevated FXIII-A transglutaminase activity. Intrinsic …

Predicting The Impact Of Utility Lighting Rebate Programs On Promoting Industrial Energy Efficiency: A Machine Learning Approach, Phillip Shook, Jun-Ki Choi

Mechanical and Aerospace Engineering Faculty Publications

Implementation costs are a major factor in manufacturers' decisions to invest in energy-efficient technologies. Emerging technologies in lighting systems, however, typically require small investment costs and offer short, simple payback periods, due, in part, to federal, state, and utility incentive programs. Recently, however, certain state and federal mandates have reduced the support for and efficacy of electricity utility incentivizing programs. To determine the impact of such support programs, this study examined historical data regarding lighting retrofit savings, implementation costs, and utility rebates gathered from 13 years of industrial energy audits by a U.S. Department of Energy Industrial Assessment Center in …

Teaching Learning Newsletter Vol 2 Issue 2, Sastra Deemed To Be University

TLC Newsletter

No abstract provided.

An Analysis And Comparison Of The Missional Doctrinal Hermemeutics Of Kevin J. Vanhoozer And Veli-Matti Kärkkäinen, With Emphasis On Their Notions Of God, Eschatology, And Mission, Elmer Guzman

Andrews University Seminary Studies (AUSS)

This is a dissertation abstract by Elmer Guzman.

"1 Peter: A Commentary"[Review]/Keener, Craig S, Thomas Shepherd

Andrews University Seminary Studies (AUSS)

This is a book review by Thomas Shepherd.

User Satisfaction With Epic/Sunquest Laboratory Information System In A Hospital Laboratory: A Guide For Optimizing Lis User Experience, Aihuan Li

MSMLS Capstone Projects

Abstract

With the development and the increase of using digital information in healthcare system, laboratory information system (LIS) has become a significant part in medical professionals’ job. The topic of assessing users’ satisfaction of using LIS on their job base, is important for the software development and laboratory management to improve the system’s performance.

The aim of this project is twofold. First, it will develop a survey that includes the Questionnaire for User Interaction Satisfaction (QUIS) and case-specific practical questions to evaluate the overall performance of Sunquest/Epic on the base of a clinical laboratory technologist’s job routine. Second, the project …

Delegates At Lake Union Constituency Session Vote To Affirm The Leadership: "Together In Mission: I Will Go" Formally Adopted As Theme For Next Four Years, Debbie Michel

Lake Union Herald

No abstract provided.

Orphan Drugs: Designations, Approvals, And Prices In The Us, Hana Althobaiti

Pharmaceutical Sciences (PhD) Dissertations

Introduction. Rare disease drug approvals have accelerated significantly in recent years. Even with these advances, patients continue to face challenges in receiving treatment, with most rare diseases lacking any approved treatments. Moreover, even when a treatment is available, it does not always reach the patients who benefit from it.

Objectives. This dissertation assessed the characteristics of orphan drug designations and approvals and the factors associated with the time lag between orphan designation and approval in the US from 1983 to 2021. It also evaluated the treatment cost of orphan and non-orphan drugs and factors explaining the treatment cost of new …

Entrepreneurial Imaginativeness: A Janusian-Cognition Lens On The Role Of Multicultural Experience, Robert J. Pidduck, Daniel R. Clark, Yejun Zhang

Management Faculty Publications

A burgeoning stream of research is emerging on the importance of entrepreneurial imaginativeness in the new venture development process. Empirical studies so far have focused predominantly on its ideation-based outcomes—the number and quality of ideas produced. Knowledge remains scant, however, on its antecedent mechanisms and mediating role in nascent venturing. Drawing from a novel Janusian-thinking lens, we integrate another growing research stream in entrepreneurship—multicultural experience—to probe how the creative, social, and practical cognitive schemas underpinning entrepreneurial imaginativeness can be cultivated through dimensions of perhaps the most distinctive form of cultural exposure: living abroad. We find evidence across two studies that …

Gender Disparity In Covid-19 Impacts On Academic Careers: An Agent-Based Model, Mai P. Trinh, Chantal Van Esch

Management Faculty Publications

The gender gap in academia has arguably been widened by the COVID-19 pandemic, but little systemic data exists to quantify this gap, let alone to predict how it will play out in the near future. This study sets out to answer the research questions, “What are the short- and long-term impacts of the COVID-19 pandemic on the gender gap in academia?” and “How effective would institutional policies designed to help faculty during the pandemic be?”. To answer these research questions, we use agent-based modeling (ABM) coupled with secondary data from various sources to develop a simulation of academia before and …

Effects Of Universal Design For Learning On Faculty And Student Outcomes In Postsecondary Online Courses, Michael P. Matis Ph.D

Leadership Studies

As diversity of student enrollment increases, postsecondary institutions
must address the inclusiveness of physical and virtual learning environments.
Doing so requires engaging faculty in a conversation about their online pedagogy
and course design. This study employs Universal Design for Learning (UDL) as a
means for faculty to reflect on and solve instructional problems in their courses. It
follows a sequential, exploratory, quasi-experimental, mixed-methods approach.
Instructor-focused, in-depth interviews capture the experience of instructors as
they reflect on their personal history that led them to teaching. They identified a
portion of one of their online courses to improve and selected modifications
inspired …

Integrin-Mediated Mechanotransduction Controls Activation Of Yap And Invasive Growth Of Breast Cancer, Xiaobo Wang

Dissertations and Theses (Open Access)

Tumor extracellular matrix (ECM) stiffness is correlated with the aggressiveness of breast cancer. Integrin-mediated adhesion and signaling are crucial for mammary tumorigenesis and tumor progression, in which focal adhesion kinase (FAK) - Src family kinases (SFKs) serves as a hub to relay the mechanical cues from the ECM. We have investigated the mechanisms through which integrin signaling controls mammary tumorigenesis and found that integrin-mediated mechanotransduction controls invasive growth of breast cancer cells in stiff matrices through activation of FAK and YAP. Mechanistic studies revealed that integrin signaling induces - via activation SFKs - tyrosine phosphorylation and inactivation of LATS1 and …

The Functional Role Of Anatomical Feedback Connections In Visual Attention, Samantha Debes

Dissertations and Theses (Open Access)

Entrenched in a dense, highly connected network, cortical neurons receive heterogeneous inputs from diverse connections, including local feedforward and feedback signals. Over the years, neuroscientists have focused on feedforward and local connections, amassing a wealth of information on the purpose of these signals. However, the functional role of feedback connections remains a mystery, despite their sheer abundance and prevalence when compared to feedforward connections. The field has long hypothesized that feedback acts as a conduit for attentional signals, carrying them throughout the brain. Previous work on this topic has been variable. Though cognitively demanding neural processes, like attention, have traditionally …

Defining The Cooperation Between Mhc-I And Mhc-Ii Neoantigen-Driven T Cell Responses To Develop Effective Personalized Immunotherapies, Charmelle Williams

Dissertations and Theses (Open Access)

Immune checkpoint therapy (ICT) (e.g. anti-CTLA-4 (α-CTLA-4), anti-PD-1 (α-PD-1)) enables durable T cell-dependent anti-tumor immunity in certain cancer patients. Since a subset of patients respond to ICT, this work aims at developing a more in-depth understanding of T-cell responses to MHC class I (MHC-I) and MHC class II (MHC-II) tumor antigens that are derived from aberrant expression of non-mutant antigens or driver and passenger somatic alterations that can function as tumor neoantigens. We used a poorly immunogenic Braf^v600e Pten^-/- Cdkn2a^-/- YUMM1.7 (Y1.7) murine melanoma line with a paucity of endogenous neoantigens that is unresponsive to ICT, and …

A Qualitative Case Study Of Health-Related Baccalaureate And Graduate Web-Based Simulated Clinical Learning Platforms, Kathrine Choura Branch

Dissertations

Simulation has been recognized as a teaching, learning, evaluation, and research strategy based on learning theories, that has come to play a significant role in healthcare education (Beal et al., 2017; La Cerra et al., 2019). Health-related academic programs in higher education have traditionally used simulation to fill gaps in learning and strengthen students’ clinical and critical thinking skills in conjunction with didactic classroom content, laboratory practice, and clinical education in the community setting (Hayden et al., 2014). With the onset and unpredictability of COVID-19, there was almost an immediate need for health-related academic programs across the world to transition …

Halmos College Graduate Academic Calendar 2022-2023, Halmos College Of Arts And Sciences (Hcas)

HCAS Academic Calendars

No abstract provided.

2022-August-01-Etsu One Of America's Best-In-State Employers, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – East Tennessee State University has been recognized by Forbes in its 2022 listing of America’s Best-in-State Employers.

The listing on Forbes.com was compiled by Forbes and Statista based on data from an independent survey taken by approximately 70,000 U.S. employees working for businesses with at least 500 employees across 25 industry sectors. Direct recommendations from employees, as well as indirect recommendations from workers in industry, were collected in the compilation of rankings. The survey considered every aspect of employees’ experience, including working conditions, salary, growth potential and diversity.

ETSU, which is one of the largest employers in …

2022-August-01-Treating Gambling Disorders - Bucwire, University Marketing And Communication, East Tennessee State University

ETSU News

East Tennessee State University is home to the second clinic in the state to treat individuals whose lives have been significantly harmed by gambling, thanks to a $1.2 million grant by the Tennessee Department of Mental Health and Substance Abuse Services (MHSAS).

This grant was recently awarded to The Institute for Gambling Education and Research (TIGER) at the University of Memphis (UM) to expand gambling research and treatment services for all Tennesseans. “In the next five years, our partnership with MHSAS will make Tennessee a leader in managing gambling harms experienced by the people living in our communities,” Ginley said. …

Timber Buckling Restrained Brace, Faith Sharp, Armando Castaneda Jr

Architectural Engineering

The timber buckling-restrained brace (TBRB) experiment at California Polytechnic State University, San Luis Obispo (Cal Poly), began in 2018 with the goal of finding whether timber may provide proper restraint against buckling of a steel brace. The TBRB was motivated by the limited lateral force resisting systems (LFRS) available for low-to-mid-rise, type V construction; this system would provide strength and ductility at a scale and level of cost appropriate to timber construction.

Early research consisted of uniaxial component testing, where researchers played with the balance between the core brace design and utilization of timber casings for buckling restraint, with minimal …

Engl 110: College Writing (Comedy, Satire, & Persuasion), Scott R. Kapuscinski

Open Educational Resources

This syllabus provides a themed approach to Freshman composition. Students are tasked with composing three essays in three distinct styles. Student engagement is high through the use of student-sourced primary sources (funny videos from YouTube, etc.) and the emphasis on thesis building and critical thinking.

Section 1: Comedy & the thesis-based essay

Section 2: Satire & writing to persuade

Section 3: Satire in Art & independent research

Water

In Case You Missed It

AUGUST 2022

Emergent Landscapes Of Renewable Energy Storage: Considering Just Transitions In The Western United States, Bethani Turley, Alida Cantor, Kate Berry, Sarah Knuth, Dustin Mulvaney, Noel Vineyard

Geography Faculty Publications and Presentations

Governments, utilities, and energy companies are increasingly looking towards energy storage technologies to extend the availability of variable renewable power sources such as solar and wind. In this Perspective, we examine these fast-shifting developments by mapping and analyzing landscapes of renewable energy storage emerging across the Western United States. We focus on the rollout of several interrelated leading technologies: utility-scale lithium-ion batteries, supported by increasing regional lithium mining, and proposals for new pumped storage hydropower. Drawing on critical resource geography, we examine energy storage as both a component of renewable transition and as its own driver of landscape transformation, resource …

Projected Changes In Atmospheric Ridges Over The Pacific-North American Region Using Cmip6 Models, Paul C. Loikith, Deepti Singh, Graham P. Taylor

Geography Faculty Publications and Presentations

Projected changes in atmospheric ridges and associated temperature and precipitation anomalies are assessed for the end of the twenty-first century in a suite of 27 models contributing to phase 6 of the Coupled Model Intercomparison Project (CMIP6) under a high-end emissions scenario over the Pacific–North American region. Ridges are defined as spatially coherent regions of positive zonal anomalies in 500-hPa geopotential height. The frequency of ridge days in the historical period varies by geography and season; however, ridge days are broadly more common over the region in winter and least common in summer. The CMIP6 models are credible in reproducing …

A Heuristic For The Two-Echelon Multi-Period Multi-Product Location–Inventory Problem With Partial Facility Closing And Reopening, Puntipa Punyim, Ampol Karoonsoontawong, Avinash Unnikrishnan, Vatanavongs Ratanavaraha

Civil and Environmental Engineering Faculty Publications and Presentations

In this paper, the two-echelon multi-period multi-product location–inventory problem with partial facility closing and reopening is studied. For each product and period, plants serve warehouses, which serve consolidation hubs, which service customers with independent, normally distributed demands. The schedule of construction, temporary partial closing, and reopening of modular capacities of facilities, the continuous-review inventory control policies at warehouses, the allocation of customer demands to hubs, and the allocation of hubs to warehouses are determined. The service levels for stockout at warehouses during lead time and the violation of warehouse and hub capacities are explicitly considered. The proposed mixed-integer non-linear program …