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Chemical Synthesis Of Astatine Labelled Asct2 Inhibitor Analogue (Ha01) As A Radiotherapeutic Agent For Theranostics, Hawk Azordegan, Cong-Dat Pham, Henry Charles Manning Aug 2022

Chemical Synthesis Of Astatine Labelled Asct2 Inhibitor Analogue (Ha01) As A Radiotherapeutic Agent For Theranostics, Hawk Azordegan, Cong-Dat Pham, Henry Charles Manning

Summer Experience 2022

No abstract provided.


U.S. Immigration Policies Affecting Mexican And Central American Youth And Their Access To Higher Education, Margaret Elizabeth Tejada Aug 2022

U.S. Immigration Policies Affecting Mexican And Central American Youth And Their Access To Higher Education, Margaret Elizabeth Tejada

Capstone Collection

Undocumented Mexican and Central American youth, many of whom hold approved or pending Special Immigrant Juvenile Status (SIJS), Deferred Action for Childhood Arrivals (DACA), and Central American Minor Refugee and Parole Program (CAM) applications, are a growing population in the United States who are eager to pursue higher education like their U.S. Citizen and U.S. Lawful Permanent Resident peers. Yet, they are significantly limited by federal, state, and institutional policies that are geared towards the success of students with legal status. Through relevant literature and interviews with policy experts and educators who work directly with these youth and/or the regulations …


A Delphi Study Of The Skills Necessary For A Speech-Language Pathologist Or Occupational Therapist To Be Successful In A Leadership Position, Jessica Miller Aug 2022

A Delphi Study Of The Skills Necessary For A Speech-Language Pathologist Or Occupational Therapist To Be Successful In A Leadership Position, Jessica Miller

Dissertations

Purpose: The purpose of this Delphi study was to identify the skills necessary for a speech-language pathologist or occupational therapist to be successful in a leadership position using an expert panel. In addition, the purpose was to rate the identified skills based on importance and lastly to determine the activities experts recommend to acquire the top-rated skills. Methodology: This study used a three-round Delphi method to collect data from expert leaders in speech-language pathology and occupational therapy. In Round 1, the expert panel was asked to identify the skills necessary to transition from a speech-language pathologist or occupational therapist to …


How Exemplary High School Principals Who Utilize Heart-Led Principles Achieve Extraordinary Results, Jeyan Danesh Aug 2022

How Exemplary High School Principals Who Utilize Heart-Led Principles Achieve Extraordinary Results, Jeyan Danesh

Dissertations

Purpose: The purpose of this phenomenological study was to describe how exemplary high school principals in Riverside and San Bernardino counties lead from the heart using Mark Crowley’s four principles (building a highly engaged team, connecting on a personal level, maximizing employee potential, and valuing and honoring achievements) to accomplish extraordinary results in their organizations. Methodology: Semistructured interviews were conducted with 8 high school principals to better understand how the use of heart-led principles can lead to extraordinary results on a high school campus. Interview data were collected, transcribed, and coded for themes, allowing the researcher to triangulate data and …


System Dynamics Modelling And Climate Change Adaptation In Coastal Areas: A Literature Review, Alberto Gabino Martínez-Hernández Aug 2022

System Dynamics Modelling And Climate Change Adaptation In Coastal Areas: A Literature Review, Alberto Gabino Martínez-Hernández

Fondazione Eni Enrico Mattei Working Papers

Climate change impacts in coastal areas (CA) have exposed coastal ecosystems to unprecedented conditions. System dynamic modelling (SD) has been used as a powerful tool to improve climate change adaptation (CCA) strategies. However, until now there are no review papers that summarize how academic literature that employs SD modelling has addressed CCA in CA. Hence, the main objective of this study is to provide an overview of the state of the art of this field. A systematic literature review was chosen as the main method of analysis, which was complemented with a bibliometric analysis and a categorization of the main …


Faculty Handbook Section Ii- All Faculty Policies And Procedures- Updated 8/5/22, All Faculty Aug 2022

Faculty Handbook Section Ii- All Faculty Policies And Procedures- Updated 8/5/22, All Faculty

Faculty Handbooks

No abstract provided.


Malignant Hyperthermia, Jessica Joos Aug 2022

Malignant Hyperthermia, Jessica Joos

Nursing Student Class Projects (Formerly MSN)

Being a proficient anesthesia provider requires vigilantly monitoring for any complications that may arise during the anesthetic period. Malignant Hyperthermia (MH) is one such complication. Succinylcholine, a neuromuscular blocking agent, and volatile anesthetic gases can initiate an MH reaction. In MH, ryanodine receptors are stimulated to release excess calcium, which causes muscle hypermetabolism. This process causes the patient to develop highly elevated temperatures, hypoxia, hypercarbia, and muscle rigidity. Left untreated, MH can be fatal. Treatment requires discontinuation of the triggering agent, administering dantrolene, providing 100% oxygen, and managing complications such as acidosis, hyperkalemia, and arrhythmias. MH is a manageable complication …


Hellp Syndrome: Hemolysis, Elevated Liver Enzymes, Low Platelets, Kimberly Roman Aug 2022

Hellp Syndrome: Hemolysis, Elevated Liver Enzymes, Low Platelets, Kimberly Roman

Nursing Student Class Projects (Formerly MSN)

The research provided was to understand a rare, life-threatening condition that occurs in pregnant women or recently postpartum women. The topic searched was HELLP Syndrome, an acronym for Hemolysis, Elevated Liver Enzymes, and Low Platelets. This syndrome is named this due to the underlying conditions in women who experience this disorder. Women can recover from HELLP Syndrome if detected early and treated appropriately, but symptoms are vague and difficult to diagnose. The best way to understand and detect this disorder is by promoting awareness and understanding the mechanisms and treatment involved. A search was conducted about the topic through research …


The Potential For Exchange-Traded Futures On Recycled Materials To Improve Recycling Efficiency, Jordan Moore, Daniel Folkinshteyn, Jordan Howell Aug 2022

The Potential For Exchange-Traded Futures On Recycled Materials To Improve Recycling Efficiency, Jordan Moore, Daniel Folkinshteyn, Jordan Howell

Rohrer College of Business Departmental Research

Recycling has substantial environmental and economic benefits, but the recycling industry is relatively inefficient. Approximately half of all recyclable material is not actually recycled, and this inefficiency is economically and environmentally costly. This paper investigates the potential for exchange-traded futures on recycled materials to increase efficiency for the recycling industry by improving the market quality for firms that buy and sell recycled materials. The aim of this study is to statistically analyze a novel data set of prices for recycled materials to demonstrate the potential efficiency gains to introducing exchange-traded futures on recycled materials. The theoretical basis for this financial …


Diabetes Mellitus Type 2, Jyoti Adhikari Aug 2022

Diabetes Mellitus Type 2, Jyoti Adhikari

Nursing Student Class Projects (Formerly MSN)

Diabetes Mellitus is a metabolic disorder that affects millions of people. The trend continues to be upward. Youth and children are not exempt from this. It is a chronic metabolic disorder characterized by persistent hyperglycemia. Causes are impaired insulin secretion, resistance to the peripheral action of insulin, or both. There are three types of diabetes: type 1, type 2, and gestational. Type 2 DM accounts for around 90% of all cases of DM. In type 2 DM, the body's response to insulin diminishes causing insulin resistance. It is commonly seen in people older than 45 years old but increasingly seen …


Hashimoto Thyroiditis, Ojaswi Bhattarai Aug 2022

Hashimoto Thyroiditis, Ojaswi Bhattarai

Nursing Student Class Projects (Formerly MSN)

Hashimoto's thyroiditis (HT) is a type of autoimmune disease marked by thyroid-specific autoantibodies, which cause immune cells and antibodies to attack and kill thyroid cells. As a result, the body's mechanisms slow down, resulting in fatigue, coldness, weight gain, dry skin, and hair loss, among other symptoms. Although the exact cause of HT is unknown, it is thought to be caused by a combination of genetics, environment, physical activity, immunology, dietary intake, and epigenesis. High serum antibody concentrations against one or more thyroid antigens, as well as widespread lymphocytic infiltration of the thyroid, are clinical manifestations. Typically, HT is treated …


Comparison Of Urbanization, Climate Change, And Drainage Design Impacts On Urban Flashfloods In An Arid Region: Case Study, New Cairo, Egypt, Bassma Taher Hassan, Mohamad Yassine, Doaa Amin Aug 2022

Comparison Of Urbanization, Climate Change, And Drainage Design Impacts On Urban Flashfloods In An Arid Region: Case Study, New Cairo, Egypt, Bassma Taher Hassan, Mohamad Yassine, Doaa Amin

Faculty Journal Articles

No abstract provided.


Lgbtq+ Microaggressions In Clinical Skills Training., Andrew Givens, Gita Jaikumar, Hayden Norris, Jacqueline Tran, Elisha Vanzant, Bhawana Yadav, Emily Noonan, Linda Fuselier, Laura Weingartner Aug 2022

Lgbtq+ Microaggressions In Clinical Skills Training., Andrew Givens, Gita Jaikumar, Hayden Norris, Jacqueline Tran, Elisha Vanzant, Bhawana Yadav, Emily Noonan, Linda Fuselier, Laura Weingartner

Undergraduate Research Events

BACKGROUND

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people experience health disparities. Implicit bias and mistreatment by healthcare providers can also lead LGTBQ+ people to delay care or avoid it entirely. Clinical skills training in the care of LGBTQ+ patients is therefore critical to health equity. Standardized patient (SP) encounters allow medical students to be assessed as providers in a mock clinical setting.

METHODS

The study population was rising third-year medical students at the University of Louisville School of Medicine in 2022. Out of 149 total encounters, coders reviewed all encounters with gender diverse SPs (n=86) and coded microaggressions, which …


How System Efficacy Affects Risk Perception: Comparison Of The United States, Iran, And China Throughout The Covid-19 Pandemic, Nazanin Bani Amerian Aug 2022

How System Efficacy Affects Risk Perception: Comparison Of The United States, Iran, And China Throughout The Covid-19 Pandemic, Nazanin Bani Amerian

Dissertations

The current study fills a gap in the risk and health communication literature that deals with perception of risk. The extended parallel process model (EPPM) and associated Risk Behavior Diagnosis Scale lack consideration for attenuated perceptions of risk when people believe that some agent (e.g., government agencies or first responders) will protect them from a hazard. This project’s intention is to establish the validity of a new concept, system efficacy, as an addition to the EPPM model. System efficacy supplements current use of self and response efficacy. In addition, this study tries to investigate how culture affect risk perception by …


Taphonomic And Diagenetic Pathways To Protein Preservation, Part Ii: The Case Of Brachylophosaurus Canadensis Specimen Mor 2598, Paul Ullmann, Richard D Ash, John B Scannella Aug 2022

Taphonomic And Diagenetic Pathways To Protein Preservation, Part Ii: The Case Of Brachylophosaurus Canadensis Specimen Mor 2598, Paul Ullmann, Richard D Ash, John B Scannella

School of Earth & Environment Departmental Research

Recent recoveries of peptide sequences from two Cretaceous dinosaur bones require paleontologists to rethink traditional notions about how fossilization occurs. As part of this shifting paradigm, several research groups have recently begun attempting to characterize biomolecular decay and stabilization pathways in diverse paleoenvironmental and diagenetic settings. To advance these efforts, we assessed the taphonomic and geochemical history of Brachylophosaurus canadensis specimen MOR 2598, the left femur of which was previously found to retain endogenous cells, tissues, and structural proteins. Combined stratigraphic and trace element data show that after brief fluvial transport, this articulated hind limb was buried in a sandy, …


Usa V. Robert Johnson Aug 2022

Usa V. Robert Johnson

2022 Decisions

USDC for the Middle District of Pennsylvania


Taphonomic And Diagenetic Pathways To Protein Preservation, Part Ii: The Case Of Brachylophosaurus Canadensis Specimen Mor 2598, Paul Ullmann, Richard D. Ash, John B. Scannella Aug 2022

Taphonomic And Diagenetic Pathways To Protein Preservation, Part Ii: The Case Of Brachylophosaurus Canadensis Specimen Mor 2598, Paul Ullmann, Richard D. Ash, John B. Scannella

School of Earth & Environment Departmental Research

Recent recoveries of peptide sequences from two Cretaceous dinosaur bones require paleontologists to rethink traditional notions about how fossilization occurs. As part of this shifting paradigm, several research groups have recently begun attempting to characterize biomolecular decay and stabilization pathways in diverse paleoenvironmental and diagenetic settings. To advance these efforts, we assessed the taphonomic and geochemical history of Brachylophosaurus canadensis specimen MOR 2598, the left femur of which was previously found to retain endogenous cells, tissues, and structural proteins. Combined stratigraphic and trace element data show that after brief fluvial transport, this articulated hind limb was buried in a sandy, …


Coronavirus Update 8-4-2022, The Coronavirus Planning Team Aug 2022

Coronavirus Update 8-4-2022, The Coronavirus Planning Team

University Briefings & Virtual Events

With most students coming to campus in just a few weeks, we want to fill you in on our COVID protocols as we start the year.


Altered High-Energy Phosphate And Membrane Metabolism In Pelizaeus-Merzbacher Disease Using Phosphorus Magnetic Resonance Spectroscopy, Jeremy J. Laukka, Kevin M. Kain, Anirudha S. Rathnam, Jasloveleen Sohi, Dalal Khatib, John Kamholz, Jeffrey A. Stanley Aug 2022

Altered High-Energy Phosphate And Membrane Metabolism In Pelizaeus-Merzbacher Disease Using Phosphorus Magnetic Resonance Spectroscopy, Jeremy J. Laukka, Kevin M. Kain, Anirudha S. Rathnam, Jasloveleen Sohi, Dalal Khatib, John Kamholz, Jeffrey A. Stanley

Neurology Articles

Pelizaeus-Merzbacher disease is an X-linked recessive leucodystrophy of the central nervous system caused by mutations affecting the major myelin protein, proteolipid protein 1. The extent of the altered in vivo neurochemistry of protein, proteolipid protein 1 duplications, the most common form of Pelizaeus-Merzbacher disease, is, however, poorly understood. Phosphorus magnetic resonance spectroscopy is the only in vivo technique that can assess the biochemistry associated with high-energy phosphate and membrane phospholipid metabolism across different cortical, subcortical and white matter areas. In this cross-sectional study, whole-brain, multi-voxel phosphorus magnetic resonance spectroscopy was acquired at 3 T on 14 patients with Pelizaeus-Merzbacher disease …


Lvhn Weekly, Lehigh Valley Health Network Aug 2022

Lvhn Weekly, Lehigh Valley Health Network

LVHN Weekly

No abstract provided.


Usa V. Bryan Thornton Aug 2022

Usa V. Bryan Thornton

2022 Decisions

USDC for the Eastern District of Pennsylvania


Manuel Ayala-Hernandez V. Attorney General United States Aug 2022

Manuel Ayala-Hernandez V. Attorney General United States

2022 Decisions

Agency


Usa V. Bryan Thornton Aug 2022

Usa V. Bryan Thornton

2022 Decisions

USDC for the Eastern District of Pennsylvania


Widespread Cortical Thinning, Excessive Glutamate And Impaired Linguistic Functioning In Schizophrenia: A Cluster Analytic Approach, Liangbing Liang, Angélica M. Silva, Peter Jeon, Sabrina D. Ford, Michael Mackinley, Jean Théberge, Lena Palaniyappan Aug 2022

Widespread Cortical Thinning, Excessive Glutamate And Impaired Linguistic Functioning In Schizophrenia: A Cluster Analytic Approach, Liangbing Liang, Angélica M. Silva, Peter Jeon, Sabrina D. Ford, Michael Mackinley, Jean Théberge, Lena Palaniyappan

Neuroscience Institute Publications

Introduction: Symptoms of schizophrenia are closely related to aberrant language comprehension and production. Macroscopic brain changes seen in some patients with schizophrenia are suspected to relate to impaired language production, but this is yet to be reliably characterized. Since heterogeneity in language dysfunctions, as well as brain structure, is suspected in schizophrenia, we aimed to first seek patient subgroups with different neurobiological signatures and then quantify linguistic indices that capture the symptoms of “negative formal thought disorder” (i.e., fluency, cohesion, and complexity of language production). Methods: Atlas-based cortical thickness values (obtained with a 7T MRI scanner) of 66 patients with …


Mechanistic Understanding Of Phase Stability, Transformation, And Strengthening Mechanisms In Lightweight High Entropy Alloys And High Entropy Ceramics, Ganesh Walunj Aug 2022

Mechanistic Understanding Of Phase Stability, Transformation, And Strengthening Mechanisms In Lightweight High Entropy Alloys And High Entropy Ceramics, Ganesh Walunj

ETD Archive

High-entropy alloys (HEAs) are a novel family of solid-solution alloys that have gained international interest due to their exceptional characteristics. Because of the need from the transportation and defense sectors, lightweight HEAs have attracted researcher’s curiosity as prospective advanced materials. Low-weight high entropy alloy synthesizes using arc melting with a mass ratio of AlCrFeMnTix(0.1,0.15,0.2). The synthesized HEA is comprised of a mixture of body center cubic (bcc) and ordered bcc (L21) solid solution phases. The synthesized HEAs have heat treated at 650C, 800C, and 1150C for 1hr, 4hr after solutionized at 1150C for 2 hr to understand the effect of …


Iadls In Acute Care, Taylor Brownlie Aug 2022

Iadls In Acute Care, Taylor Brownlie

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.


Reducing The Fear Of Falling Through A Novel Fall Prevention Education Group, Eloise K. Palm Aug 2022

Reducing The Fear Of Falling Through A Novel Fall Prevention Education Group, Eloise K. Palm

Department of Occupational Therapy Entry-Level Capstone Projects

For older adults with fall risk or a history of falling, would novel fall prevention education reduce the fear of falling and enhance confidence in self to improve engagement in desired occupations? This capstone project was centered around answering that question. The setting this took place in is an inpatient rehabilitation hospital with the older adult patient population. Specifically, this includes stroke, traumatic brain injury, spinal cord injury, cardiac, orthopedic, and generally deconditioned patients. The proposed focus area being program development.

A focus on program development was demonstrated through assessing a patient’s fear of falling (FOF) at evaluation via the …


Meal Preparation Resources For Picky Eaters And Children With Type 2 Diabetes, Janelle Kangaloo Aug 2022

Meal Preparation Resources For Picky Eaters And Children With Type 2 Diabetes, Janelle Kangaloo

Department of Occupational Therapy Entry-Level Capstone Projects

This 16-week capstone project was completed at Parker Place, A Children's Health, and Wellness Center, focusing on program development. The goal of this capstone project was to implement an occupation-based approach to improve the health outcomes related to nutrition and eating for adolescent patients at Parker Place. The student offered knowledge about an occupational therapists role in feeding and nutrition in a non-traditional setting, created an interactive e-book to help patients with type II diabetes mellitus and their parents/caregivers make educated and informed choices while eating at fast-food restaurants, developed meal and snack guides for patients to reduce parent/caregiver burden …


Research Update - August 2022, Office Of Research Aug 2022

Research Update - August 2022, Office Of Research

Research Update

No abstract provided.


Physics Ph.D. Student Wins Best Speaker Award At International Conference In Spain, Ohio University College Of Arts & Sciences Aug 2022

Physics Ph.D. Student Wins Best Speaker Award At International Conference In Spain, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.