Digital Commons Network^™

Photochemical Formation Mechanisms And Applications Of Mn Oxide Nanomaterials, Zhenwei Gao

McKelvey School of Engineering Graduate Student Theses & Dissertations

Manganese (Mn) oxides are ubiquitous in aquatic and terrestrial environments, and the rich redox chemistry of manganese is of interest in engineered systems, such as batteries and water oxidation catalysts. Mn oxides have large surface areas and are highly active in adsorption and redox reactions. Our research group recently reported photochemically-assisted abiotic inorganic oxidation of Mn2+(aq) to δ-MnO2 nanosheets in the presence of nitrate and without a microorganism, demonstrating that abiotic Mn oxidation processes are not negligible. My doctoral work focuses on investigating the effects of various aquatic chemistry parameters, including reactive oxygen species (ROS), peroxyl radical (ROO•), reactive halogen …

Advanced Nanomaterials And Module Designs For Efficient Photothermal Water Treatment, Deoukchen Ghim

McKelvey School of Engineering Graduate Student Theses & Dissertations

Water scarcity is one of the most serious challenges that human beings face, and the demand for clean water will continuously increase as populations grow. Creating potable water from saline water is an important way to meet global freshwater demands. However, current desalination techniques require high energy consumption and a large scale to be efficient, restricting their utilization in remote and underdeveloped areas. These constraints motivate the development of sustainable water treatment methods that can be used with less energy input, in small modular configurations, and in off-grid water treatment systems. As an abundant and renewable energy source, sunlight has …

Measuring G Protein Activation With Spectrally Resolved Fluorescence Fluctuation Spectroscopy, Daniel Foust

McKelvey School of Engineering Graduate Student Theses & Dissertations

Fluorescence fluctuation spectroscopy (FFS) is comprised of a set of statistical techniques used to learn information about fluorescence particles by analyzing intensity fluctuations in signals detected from a fluorescence spectrometer or microscope. In biological contexts, FFS is commonly used to quantify the concentrations, molecular brightnesses, and transport properties (e.g. diffusion coefficients) of labeled biomolecules. In particular, the molecular brightness parameter is valuable because it can be used to quantify oligomerization of biomolecules. Therefore, FFS has emerged as an attractive tool for measuring protein-protein interactions in live cells. This dissertation describes the development of image-based, multicolor FFS techniques. Image-based FFS is …

Soft Electronics And Sensors For Wearable Healthcare Applications, Li-Wei Lo

McKelvey School of Engineering Graduate Student Theses & Dissertations

Wearable electronics are becoming increasingly essential to personalized medicine by collecting and analyzing massive amounts of biological signals from internal organs, muscles, and blood vessels. Conventional rigid electronics may lead to motion artifacts and errors in collected data due to the mismatches in mechanical properties between human skin. Instead, soft wearable electronics provide a better platform and interface that can form intimate contact and conformably adapt to human skin. In this respect, this thesis focuses on new materials formulation, fabrication, characterization of low-cost, high sensitivity and reliable sensors for wearable health monitoring applications.

More specifically, we have studied the silver …

Advancing The Assessment And Treatment Of Signs And Symptoms Of Parkinson Disease, David Scott May

WUSM Theses and Dissertations – All Programs

People with PD often report signs and symptoms that negatively impact quality of life. Among these are balance difficulties, impaired gait, and FOG. New treatment and assessment strategies for these signs and symptoms are needed, as current techniques are limited. While new treatment and assessment strategies continue to emerge, gaps in knowledge persist. Deep brain stimulation (DBS) has been utilized in many people with PD throughout the 21st century, but it is unknown specifically how subthalamic nucleus deep brain stimulation (STN-DBS) affects balance. Alternative treatment strategies, such as a dental mouthpiece, have also been proposed. While dental mouthpieces have shown …

The Cost Of Child Support: Policy Design And Father Identity, Lara Markovitz

Brown School Graduate Student Theses and Dissertations

Child support policy is one of the key forces in the lives of families in the U.S., where 1 in 4 children and half of African American children live apart from their fathers (Carlson et al., 2017; Grall, 2020; U.S. Census Bureau, 2014). Most unmarried fathers of newborns express a strong desire and commitment to their children (Carlson & McLanahan, 2002; England & Edin, 2007). However, by the time their children turn five, fathers'; involvement (caregiving and time, provision of child support) diminishes greatly (Turner & Waller, 2017). This decrease in father involvement among low-income NRFs is thought to be …

Performance Of Actively Managed Exchange Traded Funds, Xuan None Li

Olin Business School Graduate Student Theses and Dissertations

Investors who want access to active asset management can choose to invest in actively managed exchange traded funds (AMETFs), actively managed non-transparent ETFs (ANETFs) or mutual funds. Three major differences of AMETFs, ANETFs and mutual funds are the venues funds are traded on, tax liabilities, and disclosure requirements. This paper exploits the 2019 SEC rulings on ETFs to study empirically which fund structure for active asset management delivers the best return performance and explores what are the driving forces behind the superior performance. I find that for equity funds, AMETFs is associated with 0.158% lower monthly returns than mutual fund, …

Origin Of Value Creation: The Role Of Delayed Intuition In Entrepreneurial Problem Framing, Chan Hyung Park

Olin Business School Graduate Student Theses and Dissertations

Highly successful entrepreneurial ventures often result from solving problems that have not been solved before (i.e., entrepreneurial problems). The problem-solving and entrepreneurship literatures indicate that individuals need to develop novel problem frames—uncommon interpretations of observable needs or pain points (i.e., symptoms) signaling the problems—to create solutions that other people would not typically think of and generate unique value that is key to entrepreneurial success. However, developing novel frames of entrepreneurial problems is difficult for two reasons. The symptoms of the problems are ambiguous and unstructured, and the structured information to find the right frame of problems is costly to acquire. …

Association Between The Baseline Gene Expression Profile In Periapical Granuloma And Periapical Wound Healing After Surgical Endodontic Treatment, Muhammad Adeel Ahmed, Fizza Nazim, Khalid Ahmed, Muhammad Furqan Bari, Abdulaziz Abdulwahed, Ahmed A. Almokhatieb, Yaseen Alalvi, Tariq Abduljabbar, Muhammad Nouman Mughal, Syed Hani Abidi

Department of Biological & Biomedical Sciences

In this study, we have investigated the association between the baseline gene expression profile in periapical granuloma and periapical wound healing after surgical endodontic treatment. Twenty-seven patients aged between 15 and 57 years underwent periapical surgery. The retrieved periapical tissue sample was used for mRNA expression analysis of COL1A1, VTN, ITGA5, IL-4, TNF, ANGPT, VEGFA, and CTGF. All patients were recalled after 6 and 12 months for periapical healing evaluation. Healing was then correlated with baseline gene expression. Healing was observed in 15 patients at the end of 6 months, which increased to 21 patients after 12 months. Six patients …

Distribution, Ecology, Morphology, And Status Of The Inyo Mountains Salamander (Batrachoseps Campi), Christopher J. Norment

Western North American Naturalist

Between 2009 and 2019, I studied the distribution and ecology of the Inyo Mountains salamander (IMS; Batrachoseps campi). The IMS is a rarely studied species endemic to the Inyo Mountains of California, and 1 of only 2 extant salamanders whose range is restricted to desert ecosystems. I found 2 new localities, increasing the documented localities to 21. I calculated a minimum convex polygon distributional range size of 458 km2 and estimated that in the Inyo Mountains there are ca. 15,200 linear meters of IMS riparian habitat, the most common habitat for the species. IMS occurred across an elevation gradient …

Mixed-Phenotype Acute Leukemia: Clinical Diagnosis And Therapeutic Strategies

Faculty, Staff and Student Publications

Mixed-phenotype acute leukemia (MPAL) comprises a heterogenous group of leukemias that are genetically, immunophenotypically, and clinically, diverse. Given the rarity of the disease, the diagnosis and treatment of MPAL is extremely challenging. Recent collaborative efforts have made significant progress in understanding the complex genomic landscape of MPAL. Some retrospective studies support starting ALL-type induction followed by an allogeneic stem cell transplant(allo-sct) in the first complete remission; however, due to the inherent bias of retrospective data and small case series, a prospective validation of AML- and ALL-based regimen, and the incorporation of targeted therapies based on genetics and immunophenotype are warranted. …

On The Thom Isomorphism For Groupoid-Equivariant Representable K-Theory, Zachary J. Garvey

Dartmouth College Ph.D Dissertations

This thesis proves a general Thom Isomorphism in groupoid-equivariant KK-theory. Through formalizing a certain pushforward functor, we contextualize the Thom isomorphism to groupoid-equivariant representable K-theory with various support conditions. Additionally, we explicitly verify that a Thom class, determined by pullback of the Bott element via a generalized groupoid homomorphism, coincides with a Thom class defined via equivariant spinor bundles and Clifford multiplication. The tools developed in this thesis are then used to generalize a particularly interesting equivalence of two Thom isomorphisms on TX, for a Riemannian G-manifold X.

Smokejumper Obituary: Lockwood, Charles Melvin “Chuck” (Missoula 1965), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Van Wagtendonk, Jan W. (Cave Junction 1960), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

"I Need More Knowledge": Qualitative Analysis Of Oncology Providers' Experiences With Sexual And Gender Minority Patients, Christina L Tamargo, Edith P Mitchell, Lynne Wagner, Melissa A Simon, Ruth C Carlos, Bruce J Giantonio, Matthew B Schabath, Gwendolyn P Quinn

Department of Medical Oncology Faculty Papers

Background: While societal acceptance for sexual and gender minority (SGM) individuals is increasing, this group continues to face barriers to quality healthcare. Little is known about clinicians' experiences with SGM patients in the oncology setting. To address this, a mixed method survey was administered to members of the ECOG-ACRIN Cancer Research Group.

Materials and methods: We report results from the open-ended portion of the survey. Four questions asked clinicians to describe experiences with SGM patients, reservations in caring for them, suggestions for improvement in SGM cancer care, and additional comments. Data were analyzed using content analysis and the constant comparison …

Polarization Angle Dependence Of Vertically Propagating Radio-Frequency Signals In South Polar Ice, Davez Bensson, Ilya Kravchenko, Krishna Nivedita

Department of Physics and Astronomy: Faculty Publications

To better understand the effect of ice properties on the science reach of radio experiments designed to measure ultrahigh energy neutrinos (UHEN), we recently considered the timing and amplitude characteristics of radio-frequency (RF) signals propagating along multi-kilometer, primarily horizontal trajectories through cold Polar ice at the South Pole. That analysis indicated satisfactory agreement with a model of ice birefringence based on ice crystal (ĉ-axis) data culled from the South Pole Ice Core Experiment (SPICE). Here we explore the geometrically complementary case of signals propagating along primarily vertical trajectories, using extant data from the Askaryan Radio Array (ARA) experiment, …

The Use Of Gpr To Investigate The Effect Of Steel Fiber Distribution On The Mechanical Behavior Of Frc, Paola Machado Barreto Manhães, José Tavares Araruna Júnior, Genda Chen, Neil Lennart Anderson, Erik Valloti Pereira, Flávio De Andrade Silva

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The present work focuses on the steel fiber distribution in self-consolidating concrete short beams. The objective is to assess the feasibility of the ground penetrating radar (GPR) in evaluating the homogeneity of fibers within concrete materials, for use in testing laboratories to study the modes of placing and compaction employed for preparing specimens during quality control or material development. Self-consolidating concrete beams were cast, tested, and evaluated. A GPR survey employing a concrete scanning system with a shielded 1.2 GHz center frequency was performed on self-consolidating casted short beams just before a monotonic four-point bending test was carried out. After …

Anti-Washout Concrete: An Overview, Hao Lu, Xiao Sun, Hongyan Ma

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Anti-washout concrete (AWC) is a special cement-based material that can be directly employed in underwater environments without dispersion. It was developed around 50 years ago, and more than 150 journal articles and technical reports have been published. This paper provides a holistic review about the basic fresh-state and hardened-state properties of the AWC, such as water (washout) resistance, consistency, bleeding and segregation resistance, mechanical properties, and durability, as well as relevant testing methods. The discrepancies between AWC's characteristics and those of conventional concrete are clearly presented. The mixture compositions, supplementary cementitious materials (SCMs), and other conditions that affect AWC's performance …

Re-Analysis And Additional Information Needed To Inform Conclusions Comment On Halenova Et Al Deuterium-Depleted Water As Adjuvant Therapeutic Agent For Treatment Of Diet-Induced Obesity In Rats, Colby J Vorland, Xiwei Chen, Daniella E Chusyd, Luis M Mestre, Stephanie L Dickinson, David B Allison, Andrew W Brown

Children’s Nutrition Research Center Staff Publications

We were interested to read the report by Halenova et al. [...].

Mla Lindberg Fellowship Evidence Based Practice: A Practical Guide For Health Information Professionals, Jonathan Eldredge

Posters and Presentations

No abstract provided.

Hern - Health Experience Research Network, Lisa M. Acuff, Allison B. Cruise

Posters and Presentations

No abstract provided.

Reconciliation Framework: Response To The Report Of The Truth And Reconciliation Commission Taskforce, Jonathan M. Pringle

Publications

Released in February 2022, the Reconciliation Framework is designed for non-Indigenous archivists in Canada who manage Indigenous holdings in their repositories, from acquisitions to outreach and all processes in-between. The document positions itself well amongst other related international standards that advocate for a reciprocal, ongoing relationship between archival institutions and the Indigenous communities they purport to represent and serve. The journey to final publication reaches back not only years and decades but also centuries, considering it was borne out of the aftermath of the terrible history of residential schools in North America. Recent formal calls to action demanded redress through …

Building Unproblematic Searches For Indian/Alaska Native Topics, Alexis Ellsworth-Kopkowski

Posters and Presentations

No abstract provided.

Theatre Uab Grad Wins National Award, After Starting Career In Costumes Then Pursuing Her Ph.D., Shannon Thomason

Browse All News

No abstract provided.

Jack To Retire After A Decade As Dean Of Collat School Of Business, Alicia Rohan

Browse All News

No abstract provided.

Ndls Communicator: Week Of 08.15.22, Notre Dame Law School

NDLS Communicator

The Latest News

• U.S. Supreme Court Justice Samuel Alito delivered the keynote address at the 2022 Notre Dame Religious Liberty Summit
• Religious Liberty Summit Awards
• RLI Summit Videos
• Professor Samuel Bray elected to the American Law Institute
• Jay Tidmarsh was quoted in the Detroit News
• Lloyd Mayer was quoted by Exposed by CMD in two articles about the 501(c)(4) organization funded by the Koch family.
• Jimmy Gurulé was quoted by Newsweek in "Why Did Trump Plead The Fifth Amendment?—What We Do Know, What We Don't."
• Diane Desierto contributed to the new issue of the European Journal of International Law.
• Stephanie …

Comparative Genomics And Virulence Studies Of Streptomyces Soil Rot And Scab Pathogen Species, Natasha Soares

LSU Doctoral Dissertations

Comparative genomic analyses were performed to gain insights into the organization and content of the genome of Streptomyces ipomoeae, the soil rot pathogen that infects sweetpotatoes. Unlike Streptomyces scab pathogens, the thaxtomin phytotoxin gene cluster (txt) in S. ipomoeae does not appear to reside within a genomic island and has diverged from its scab pathogen counterparts. Increased usage of the rare TTA codon, particularly for the txt cluster, suggests greater translational control by the bldA tRNA in S. ipomoeae. Orthologous gene searches and secondary metabolite profiling yielded ortholog groups and metabolite gene clusters that were exclusive …

Artificial Intelligence And Machine Learning In Mobile Apps For Mental Health: A Scoping Review, M Milne-Ives, E Selby, B Inkster, C Lam, E Meinert

School of Nursing and Midwifery

Mental health conditions can have significant negative impacts on wellbeing and healthcare systems. Despite their high prevalence worldwide, there is still insufficient recognition and accessible treatments. Many mobile apps are available to the general population that aim to support mental health needs; however, there is limited evidence of their effectiveness. Mobile apps for mental health are beginning to incorporate artificial intelligence and there is a need for an overview of the state of the literature on these apps. The purpose of this scoping review is to provide an overview of the current research landscape and knowledge gaps regarding the use …

A Multi-Institutional Prediction Model To Estimate The Risk Of Recurrence And Mortality After Mastectomy For T1-2n1 Breast Cancer, Sarah M C Sittenfeld, Emily C Zabor, Sarah N Hamilton, Henry M Kuerer, Mahmoud El-Tamer, Pauline T Truong, Benjamin D Smith, Wendy A Woodward, Tracy-Ann Moo, Simon N Powell, Chirag S Shah, Alphonse G Taghian, Ibrahim Abu-Gheida, Rahul D Tendulkar

Faculty, Staff and Student Publications

Background: Post-mastectomy radiation therapy (PMRT) in women with pathologic stage T1-2N1M0 breast cancer is controversial.

Methods: Data from five North American institutions including women undergoing mastectomy without neoadjuvant therapy with pT1-2N1M0 breast cancer treated from 2006 to 2015 were pooled for analysis. Competing-risks regression was performed to identify factors associated with locoregional recurrence (LRR), distant metastasis (DM), overall recurrence (OR), and breast cancer mortality (BCM).

Results: A total of 3532 patients were included for analysis with a median follow-up time among survivors of 6.8 years (interquartile range [IQR], 4.5-9.5 years). The 2154 (61%) patients who received PMRT had significantly more …

Gray And White Matter Abnormality In Patients With T2dm-Related Cognitive Dysfunction: A Systemic Review And Meta-Analysis, Yu Han, Wen Wang, Lin-Feng Yan, Guang-Bin Cui

Faculty, Staff and Student Publications

Aims/hypothesis

Brain structure abnormality in patients with type 2 diabetes mellitus (T2DM)-related cognitive dysfunction (T2DM-CD) has been reported for decades in magnetic resonance imaging (MRI) studies. However, the reliable results were still unclear. This study aimed to make a systemic review and meta-analysis to find the significant and consistent gray matter (GM) and white matter (WM) alterations in patients with T2DM-CD by comparing with the healthy controls (HCs).

Methods

Published studies were systemically searched from PubMed, MEDLINE, Cochrane Library and Web of Science databases updated to November 14, 2021. Studies reporting abnormal GM or WM between patients with T2DM-CD and …