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Targeting The Maladaptive Effects Of Binge Drinking On Circadian Gene Expression, Courtney Ledford

University Honors Theses

Previous studies 1) support a role of circadian genes in regulating alcohol intake, and 2) reveal that harmful alcohol use alters circadian rhythms. However, there [is] minimal knowledge of the effects of chronic alcohol processes on rhythmic circadian gene expression across brain regions important for circadian biology and alcohol intake. Therefore, the present study sought to test the effects of chronic binge-like drinking on diurnal circadian gene rhythms in the master circadian pacemaker (SCN), the ventral tegmental area (VTA), and the nucleus accumbens (NAc) in High Drinking in the Dark-1 (HDID-1) mice, a unique genetic risk model for drinking to …

Graviton Scattering Amplitudes In First Quantisation, J Edwards

School of Engineering, Computing and Mathematics

We give a pedagogical review to alternative, first quantised approaches to calculating graviton scattering amplitudes, giving an introduction to string inspired approaches and presenting more recent work based on the worldline formalism of quantum field theory that is motivated by these historic results. We describe how these first quantised techniques can greatly simplify the determination of such amplitudes, in particular reducing the number of Feynman-like diagrams that enter the computation and leading to compact results.

The Papers Of Clarence Mitchell Jr., Volume Vi : The Struggle To Pass The 1960 Civil Rights Act, 1959–1960, Clarence Mitchell Jr., Denton L. Watson

Ohio University Press Open Access Books

The Civil Rights Act of 1960 aimed to close loopholes in its 1957 predecessor that had allowed continued voter disenfranchisement for African Americans and for Mexicans in Texas.

In early 1959, the newly seated Eighty-Sixth Congress had four major civil rights bills under consideration. Eventually consolidated into the 1960 Civil Rights Act, their purpose was to correct the weaknesses in the 1957 law. Mitchell’s papers from 1959 to 1960 show the extent to which congressional resistance to the passage of meaningful civil rights laws contributed to the lunch counter sit-ins in Greensboro, North Carolina, and to subsequent demonstrations. The papers …

The Timing And Development Of Infections In A Fish-Cestode Host-Parasite System, Anika M. Wohlleben, Natalie C. Steinel, Néva P. Meyer, John A. Baker, Susan A. Foster

Biology

The cestode Schistocephalus solidus is a common parasite in freshwater threespine stickleback populations, imposing strong fitness costs on their hosts. Given this, it is surprising how little is known about the timing and development of infections in natural stickleback populations. Previous work showed that young-of-year stickleback can get infected shortly after hatching. We extended this observation by comparing infection prevalence of young-of-year stickleback from 3 Alaskan populations (Walby, Cornelius and Wolf lakes) over 2 successive cohorts (2018/19 and 2019/20). We observed strong variation between sampling years (2018 vs 2019 vs 2020), stickleback age groups (young-of-year vs 1-year-old) and sampling populations.

Employee Health Center Adds Dr. Nicole Turner As Staff Physician, Edwin B. Smith

University of Mississippi News

New doctor brings family practice skills to boost patient services

Co-Twin Relationship Quality As A Moderator Of Genetic And Environmental Factors On Urinary Cortisol Levels Among Adult Twins, Joseph A. Schwartz, Scott Jessick, Jessica L. Calvi, Douglas A. Granger

Athletic Performance Research

Previous research has indicated that genetic and environmental factors shape physiological activity. Cortisol levels, in particular, have received significant attention, with studies indicating substantive heritability estimates across various sampling techniques. A related line of research has indicated that genetic and environmental factors that explain variability in cortisol levels may vary across context and experiences by way of gene-environment interactions (G×Es). Despite these findings, a limited number of studies have examined the extent to which interpersonal relationships may operate as a moderator. The current study focused on co-twin relationship quality as a source of moderation, as twins are more likely to …

Mike Srock, Oral History Interview, 2022, Matt Jones

Oral Histories

Mike Srock was an active member of the Arm of Honor Fraternity from 1965 until he was drafted by the US Armed Forces in 1967. Now an acclaimed Strength & Speed coach, Srock talks about his upbringing, education and athletic exposure in Detroit, before detailing his college experiences, academics, and friendships within the Arm of Honor. He details his off-campus living situation, the atmosphere at EMU in the 1960s, rushing for Arm of Honor, and the six kegs of beer won by his pledge class for various athletic achievements. He talks of fellow Arm Dennis Snary and his unusual method …

St. Norbert College To Hold Annual College Community Celebration With Music/Fireworks On Aug. 28, St. Norbert College

Press Releases 2022

No abstract provided.

Can A Non-Violent Video Game Impact Aggression? The Effects Of Competition And Game Difficulty On Aggressive Behaviors., Jared Carter Butler

Student Theses and Dissertations

Much of video game research has focused on the effects of violent video games. The present study sought a new approach to studying video games; one pertaining to non-violent video games. Non-violent video games were the only stimuli used within the study, something that has not been tested previously using this methodology. The effects of competition and game difficulty were analyzed using the Tangram Help/Hurt Task. Participants played Super Mario Maker 2 and then completed the Tangram Help/Hurt Task. It was predicted that a competitive and difficult non-violent video game would lead participants to act aggressively towards another individual. Results …

From The Headlines: A Textual Analysis Of Social Polarization And Discord In Times Of Pandemic Across A Century In The United States, Alexa Demarco

Undergraduate Honors Theses

Within the past century, three major pandemics have affected the United States – the Spanish Flu, AIDS, and COVID-19. Each of these pandemics has tested the capabilities of the public health sector and the social resilience of the population. Scientists have studied the viruses and implemented public health measures to limit viral transmission, but the social responses to these preventative measures proved to be difficult to predict and control. The dissonance and polarization between the public health initiatives and the response of the general public in the most recent pandemic was apparent. Was this a pattern in other pandemics? Was …

Assessing The Needs And Barriers Of Esports Players In Participating In Esports And Daily Life, Kristen Musacco, Susan Macdermott, Stephanie Stoltenberg

Summer 2022 Virtual OTD Capstone Symposium

The purpose of this study is to determine the occupational needs and barriers faced by esports players as they participate in daily life and advocate for occupational therapy's potential role. A qualitative survey of 9 participants and 6 interviews were given. Thematic analysis identified themes of stigma surrounding seeking medical intervention in esports, as well as negative perceptions of how esports are viewed. Experience with an ergonomics specialist contributed to the understanding of basic ergonomics principles, proper measurement, and assessment of stations. This needs assessment provided a basis for understanding participant experiences in relation to the role occupational therapists in …

Covid-19 Newsletter (Vol. 132), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Myosin Ii Adjusts Motility Properties And Regulates Force Production Based On Motor Environment, Omayma Alazzam, Janie Watts, Juliana Davis, Justin Reynolds, Dana N. Reinemann

Faculty and Student Publications

Introduction: Myosin II has been investigated with optical trapping, but single motor-filament assay arrangements are not reflective of the complex cellular environment. To understand how myosin interactions propagate up in scale to accomplish system force generation, we devised a novel actomyosin ensemble optical trapping assay that reflects the hierarchy and compliancy of a physiological environment and is modular for interrogating force effectors.

Methods: Hierarchical actomyosin bundles were formed in vitro. Fluorescent template and cargo actin filaments (AF) were assembled in a flow cell and bundled by myosin. Beads were added in the presence of ATP to bind the cargo AF …

Recent-Style Poetry : Pentasyllabic Regulated Verse : Wang Wei : The Poet-Buddha Of China, Zong-Qi Cai

How to Read Chinese Poetry Podcast

This episode examines how Wang Wei embodies moments of heightened perception or rather Buddhist enlightenment through his painterly depiction of a mountain climbing trip. His masterful blending of illusive images, perceptual illusion, and Buddhist worldview exemplifies his towering achievement as the poet-Buddha.

Ready All Row: Can Udentify Us?, University Of Dayton

Materials from the University of Dayton Magazine Website

Can you UDentify these members of the 1997 University of Dayton rowing team?

Evaluating The Impact Of Modic Changes On Operative Treatment In The Cervical And Lumbar Spine: A Systematic Review And Meta-Analysis, Mark J Lambrechts, Parker Brush, Tariq Z Issa, Gregory R Toci, Jeremy C Heard, Amit Syal, Meghan M Schilken, Jose A Canseco, Christopher K Kepler, Alexander R Vaccaro

Rothman Institute Papers

Modic changes (MCs) are believed to be potential pain generators in the lumbar and cervical spine, but it is currently unclear if their presence affects postsurgical outcomes. We performed a systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies evaluating cervical or lumbar spine postsurgical outcomes in patients with documented preoperative MCs were included. A total of 29 studies and 6013 patients with 2688 of those patients having preoperative MCs were included. Eight included studies evaluated cervical spine surgery, eleven evaluated lumbar discectomies, nine studied lumbar fusion surgery, and three assessed …

Effect Of The Covid-19 Pandemic On Seizure Control Status In Patients With Epilepsy, A A Asadi-Pooya, Seyed Ali Nabavizadeh, Mohsen Farazdaghi

Department of Neurology Faculty Papers

Background: Previous studies have shown that patients with epilepsy (PWE) perceived significant disruption in the quality and provision of care due to the coronavirus disease 2019 (COVID-19) pandemic. The present study aimed to investigate the effect of this pandemic on seizure control status and changes in seizure frequency in PWE.

Methods:A consecutive sample of adult PWE registered in the database of Shiraz Epilepsy Center (Shiraz, Iran) was included in the study. In July 2021, phone interviews were conducted with all selected patients. Information such as age, sex, last seizure, seizure type, and frequency during the 12 months before the …

Exploring Generation Z’S Perceptions Of Green Homes, Bhavya Rathna Kota, Luciana Debs, Taylor Davis

Purdue University Libraries Open Access Publishing Fund

In recent years, there has been an increase in environmental awareness in the United States, leading to steady growth in environmentally conscious consumerism. Looking specifically at green home marketing, understanding the consumer behavior of the next generation of homebuyers, Generation Z (GenZ), is important for environmental and business reasons. This study surveyed 116 university students to explore the influence of specific barriers and types of motivation (intrinsic, instrumental, and non-normative) on their perceptions of green homes. Our findings suggest certain barriers have more influence on GenZ consumers than others, with the perceived lack of choice in selecting Green Home Features …

Occupational Therapy And Continuous Care: Pediatric Rehabilitation For Children With Medically Complex Conditions And Severe Burns, Elise M. Mueller

Occupational Therapy Capstone Presentations

This capstone focused on developing advanced clinical knowledge and skills to treat children with medically complex conditions and severe burns. This project also incorporated interdisciplinary communication, leadership, and academic education. It took place at Madonna Rehabilitation Hospital and ChildServe Medical Daycare. The population consisted of patients treated on the pediatric floor within an inpatient rehabilitation hospital, children receiving occupational therapy services in a pediatric outpatient setting, and children appropriate for medical daycare. At Madonna Rehabilitation Hospital, 12 clients under the age of 21 and four clients over 21 received occupational therapy in the inpatient setting, and six children received outpatient …

Independent - Aug. 16, 2022, Monty Stites

The Independent (1988-present)

No abstract provided.

Exploring The Semantics And Functionality Of Ghanaianisms, James Nsoh Adogpa

Lingnan Theses (MPhil & PhD)

Ghanaian users of English have developed a variety of English that includes, among other things, lexical items whose usage and meanings are impregnated with cultural values, concepts and meanings. In this thesis I call these items Ghanaianisms and argue that their significance is to allow an institutionalized second language to acquire new meanings in the new context, in order to function effectively and to express new identities. The new norms that have arisen in the Ghanaian context include both feature norms and behavioural norms, and both were investigated as part of the study. The methodology used is ethnographic in nature. …

Housing Rights Initiative, Inc. V. Century 21 Dawns Realty

All Decisions

No abstract provided.

Axonal Architecture Of The Mouse Inner Retina Revealed By Second Harmonic Generation, Arafat Meah, Vinessia Boodram, Festa Bucinca-Cupallari, Hyungsik Lim

Publications and Research

We describe a novel method for visualizing the network of axons in the unlabeled fresh wholemount retina. The intrinsic radiation of second harmonic generation (SHG) was utilized to visualize single axons of all major retinal neurons, i.e., photoreceptors, horizontal cells, bipolar cells, amacrine cells, and the retinal ganglion cells. The cell types of SHG + axons were determined using transgenic GFP/YFP mice. New findings were obtained with retinal SHG imaging: Müller cells do not maintain uniformly polarized microtubules in the processes; SHG + axons of bipolar cells terminate in the inner plexiform layer (IPL) in a subtype-specific manner; a subset …

Three-Dimensional Printed Abdominal Imaging Windows For In Vivo Imaging Of Deep-Lying Tissues, Mitchell Kuss, Ayrianne J. Crawford, Olawale A. Alimi, Michael A. Hollingsworth, Bin Duan

Department of Mechanical and Materials Engineering: Faculty Publications

The ability to microscopically image diseased or damaged tissue throughout a longitudinal study in living mice would provide more insight into disease progression than having just a couple of time points to study. In vivo disease development and monitoring provides more insight than in vitro studies as well. In this study, we developed permanent 3D-printed, surgically implantable abdominal imaging windows (AIWs) to allow for longitudinal imaging of deep-lying tissues or organs in the abdominal cavity of living mice. They are designed to prevent organ movement while allowing the animal to behave normally throughout longitudinal studies. The AIW also acts as …

Permafrost Landscape History Shapes Fluvial Chemistry, Ecosystem Carbon Balance, And Potential Trajectories Of Future Change, Scott Zolkos, Suzanne E. Tank, Steven V. Kokelj, Robert G. Striegl, Sarah Shakil, Carolina Voigt, Oliver Sonnentag, William L. Quinton, Edward A. G. Schuur, Donatella Zona, Peter M. Lafleur, Ryan C. Sullivan, Masahito Ueyama, David P. Billesbach, David Cook, Elyn R. Humphreys, Philip Marsh

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Intensifying permafrost thaw alters carbon cycling by mobilizing large amounts of terrestrial substrate into aquatic ecosystems. Yet, few studies have measured aquatic carbon fluxes and constrained drivers of ecosystem carbon balance across heterogeneous Arctic landscapes. Here, we characterized hydrochemical and landscape controls on fluvial carbon cycling, quantified fluvial carbon fluxes, and estimated fluvial contributions to ecosystem carbon balance across 33 watersheds in four ecoregions in the continuous permafrost zone of the western Canadian Arctic: unglaciated uplands, ice-rich moraine, and organic-rich lowlands and till plains. Major ions, stable isotopes, and carbon speciation and fluxes revealed patterns in carbon cycling across ecoregions …

Constraints On The Evolution Of Toxin-Resistant Na,K-Atpases Have Limited Dependence On Sequence Divergence, Shabnam Mohammadi, Santiago Herrera-Álvarez, Lu Yang, María Del Pilar Rodrı´Guez-Ordoñez, Karen Zhang, Jay F. Storz, Susanne Dobler, Andrew J. Crawford, Peter Andolfatto

School of Biological Sciences: Faculty Publications

A growing body of theoretical and experimental evidence suggests that intramolecular epistasis is a major determinant of rates and patterns of protein evolution and imposes a substantial constraint on the evolution of novel protein functions. Here, we examine the role of intramolecular epistasis in the recurrent evolution of resistance to cardiotonic steroids (CTS) across tetrapods, which occurs via specific amino acid substitutions to the α-subunit family of Na,K-ATPases (ATP1A). After identifying a series of recurrent substitutions at two key sites of ATP1A that are predicted to confer CTS resistance in diverse tetrapods, we then performed protein engineering experiments to test …

Age Of Diagnosis, Service Access, And Rights Of Autistic Individuals In Argentina: Caregivers Reports Of Changes And Similarities Across Time, María Cecilia Montenegro, Estefani Bernal, Sebastián Cukier, Daniel Valdez, Alexia Rattazzi, Gabriela Garrido, Analía Rosoli, Cristiane Silvestre Paula, Ricardo Garcia, Cecilia Montiel-Nava

Psychological Science Faculty Publications

Background: Many countries have developed health initiatives to protect those with disabilities and developmental concerns in the past few years. However, the needs of autistic individuals are still short of being fulfilled. Partially due to limited research expenditure, which would allow bridging the gap between evidence and practice, the long time it takes to implement passed laws, and the limited operationalization of inclusive policies.

Objective: To quantitatively examine changes in the child's age at the time of caregiver's first developmental concerns and age of diagnosis of their autistic child across 5 years. Also, to address challenges experienced by caregivers (e.g., …

Local, Worldwide Internships Introduce Titans To Workforce, Maria Harmon

News and Events (Discontinued Series)

No abstract provided.

Electron Energization Signatures In Traveling Kinetic Alfvén Waves At Storm Time Injection Fronts, A. J. Hull, P. A. Damiano, C. C. Chaston, J. R. Johnson, G. D. Reeves

Faculty Publications

The properties of traveling kinetic Alfvén waves (KAWs) and their role in energizing electrons in the inner magnetosphere during a geomagnetic storm are examined using measurements from the Van Allen Probes and Gyrofluid-Kinetic Electron (GKE) model simulations. Traveling KAWs occur in the vicinity of energetic plasma injection fronts in association with magnetic field dipolarizations. The KAWs coincide with energized field-aligned electrons at energies ≲1 keV. By using observational constraints and incorporating hot and cold electron populations, the GKE simulations are able to reproduce the observed energized electron distribution signatures. The modeling results demonstrate the crucial importance of cold electrons for …

Perspectives Of African American Women About Barriers To Breast Cancer Prevention And Screening Practices: A Qualitative Study, Abosede F. Obikunle, Bosede Ade-Oshifogun

Faculty Publications

Breast cancer is a severe illness that often has fatal consequences. Adherence to the recommendations for breast cancer surveillance is poorly practiced among African American women. The study aimed to identify barriers to preventative screening for breast cancer among African American women (AAW) using a qualitative research design. We explored the influence of personal barriers, stereotypes, socioeconomic status, culture, attitudes, and beliefs on African American women's behavior regarding breast cancer screening. Fourteen African American women were interviewed. Data analysis was completed with Interpretative Phenomenology Approach (IPA). This study's findings demonstrated that African American women perceived the barriers to breast cancer …