Digital Commons Network^™

Adapting The Fast-M Maternal Sepsis Intervention For Implementation In Pakistan: A Qualitative Exploratory Study, Sheikh Irfan Ahmed, Bakhtawar M H. Khowaja, Rubina Barolia, Raheel Sikandar, Ghulam Kubra Rind, Sehrish Rani, Raheela Rani, James Cheshire, Catherine Louise Dunlop, Lumaan Sheikh

Department of Obstetrics & Gynaecology

Objective: A maternal sepsis management bundle for resource-limited settings was developed through a synthesis of evidence and international consensus. This bundle, called 'FAST-M' consists of: Fluids, Antibiotics, Source control, assessment of the need to Transport/Transfer to a higher level of care and ongoing Monitoring (of the mother and neonate). The study aimed to adapt the FAST-M intervention including the bundle care tools for early identification and management of maternal sepsis in a low-resource setting of Pakistan and identify potential facilitators and barriers to its implementation.
Setting: The study was conducted at the Liaquat University of Medical and Health Sciences, which …

Outcome Evaluation Of Active Herts: A Community-Based Physical Activity Programme For Inactive Adults At Risk Of Cardiovascular Disease And/Or Low Mental Wellbeing, Angel M. Chater, Joerg Schulz, Andy Jones, Amanda Burke, Shelby Carr, Dora Kukucska, Nick Troop, Daksha Trivedi, Neil Howlett

School of Psychology

BackgroundA high proportion of UK adults are inactive, which can lead to a range of physical and mental health concerns. Active Herts is a community-based physical activity programme for inactive adults at risk of cardiovascular disease and/or low mental wellbeing. This paper provides a pragmatic evaluation of this programme.MethodThis longitudinal study observed 717 adults (68% female, mean age = 56.9 years) from the “Active Herts” programme. Programme users were provided with a 45-min consultation with a “Get Active Specialist,” who talked them through an Active Herts self-help booklet and then signposted them to free or subsidized local exercise sessions. Programme …

Becoming Men, Consequently: From “Contraband” To Men Through Naval Service In The American Civil War, Micah Paul Bellamy

Doctoral Dissertations and Projects

“Becoming Men, Consequently” examines the lives and experiences of African American sailors, both those free and deemed “contraband,” who served in the U.S. Navy during the Civil War, providing a narrative look into the history of African American naval service from the French and Indian War through the Civil War and finishes at the end of World War II. Examining African American men serving in the U.S. Navy during the Civil War offers a novel analysis of their reasons for enlistment, experiences in the ranks, life after the navy, and their life after the navy. The investigation into the question …

A Phenomenological Study Of The Experiences Of School Leaders' Preparation And Leadership Of Inclusive And Special Education Programs, April Denise Burwell

Doctoral Dissertations and Projects

This transcendental phenomenological study describes how public school leaders experience learning and leading inclusive and special education programs. Two theories guided this study Knowles’s adult learning theory and Mezirow’s transformative learning theory. The central research question for this study was how school leaders describe their professional experiences in leading inclusive and special education programming. The 10 participants in this study were school leaders endorsed in administration and supervision K–12. A criterion sampling was utilized for participant selection across three school districts in Central Virginia. The phenomenological approach was applied during data analysis. Horizontalization and coding were used to identify common …

Improving Inattentiveness Through Asymmetric Tonic Neck Reflex Integration Exercises: A Quantitative, Quasi-Experimental Study, Arrin Christine Brummett

Doctoral Dissertations and Projects

The purpose of this quantitative, quasi-experimental study was to understand the difference in the posttest detectability scores, as measured by the Conners Kiddie Continuous Performance Test 2nd edition, among early childhood students participating in various activity types, including ATNR integration exercises, running exercises, or sedentary work, when controlling for pretest detectability scores at schools in rural north Texas using a nonequivalent control-group, pretest-posttest design. This study built on the theory of structural cognitive modifiability and helped to expand research regarding the impact of a specific type of physical activity, namely asymmetric tonic neck reflex integration exercises, on focal inattentiveness, a …

Can Body Mass Index Influence The Skin Temperature Of Adolescents? A Preliminary Study With The Use Of Infrared Thermography, Hamilton Henrique Teixeira Reis, Ciro José Brito, Alisson Gomes Da Silva, Manuel Sillero-Quintana, Victória Esther Teixeria Reis, Francisco Zacaron Werneck, Ismael Fernández-Cuevas, Matheus Santos Cerqueira, João Carlos Bouzas Marins

Department of Nutrition and Health Sciences: Faculty Publications

– Infrared thermography (IRT) has been used to assess skin temperature (Tsk), especially during the COVID-19 pandemic, as an important tool in medical screening not only of the general population, but also of young athletes. However, the subcutaneous adipose tissue can act as an insulator when the Tsk is assessed by IRT, modifying the normal Tsk data and leading to their misinterpretation. Considering that the body mass index (BMI) is an important predictor of obesity, the objective of this study was to verify if the Tsk measured by IRT is affected by the BMI in adolescents. A preliminary study was …

Pitfalls And Guidelines For Using Time-Based Git Data, Samuel W. Flint, Jigyasa Chauhan, Robert Dyer

School of Computing: Faculty Publications

Many software engineering research papers rely on time-based data (e.g., commit timestamps, issue report creation/update/close dates, release dates). Like most real-world data however, time-based data is often dirty. To date, there are no studies that quantify how frequently such data is used by the software engineering research community, or investigate sources of and quantify how often such data is dirty. Depending on the research task and method used, including such dirty data could aect the research results. This paper presents an extended survey of papers that utilize time-based data, published in the Mining Software Repositories (MSR) conference series. Out of …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Ionic Liquid Pilocarpine Analog As An Antiglaucoma Drug Candidate, Juan Wang, Boxuan Li, Jing Tang, Li Qiu, Xin Qiao, Na Xu, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Ionic liquid pilocarpine analog [Pilo-OEG]Cl, the first-of-its-kind ionic liquid antiglaucoma drug candidate, is synthesized and reported. To synthesize [Pilo-OEG]Cl, pilocarpine was reacted with the oligo-polyethylene glycol chloride, 2-[2-(2-chloroethoxy)ethoxy] ethanol, to form an ionic liquid molecule with an imidazole cation and a chloride anion. The chemical structure of [Pilo-OEG]Cl was confirmed with 1H NMR spectroscopy. Compared with pilocarpine (Pilo) and pilocarpine hydrochloride (PiloHCl), [Pilo-OEG]Cl has improved structural stability according to pH measurements and LC-MS analysis. The corneal permeability coefficient of [Pilo-OEG]Cl is 2-fold higher than that of Pilo and 8-fold higher than that of PiloHCl. [Pilo-OEG]Cl does not show apparent toxicity …

Aldehyde Dehydrogenase 2 Activator Augments The Beneficial Effects Of Empagliflozin In Mice With Diabetes-Associated Hfpef, Guodong Pan, Bipradas Roy, Shailendra Giri, David E. Lanfear, Rajarajan A. Thandavarayan, Ashrith Guha, Pablo A. Ortiz, Suresh S. Palaniyandi

Hypertension and Vascular Research Articles

To ameliorate diabetes mellitus-associated heart failure with preserved ejection fraction (HFpEF), we plan to lower diabetes-mediated oxidative stress-induced 4-hydroxy-2-nonenal (4HNE) accumulation by pharmacological agents that either decrease 4HNE generation or increase its detoxification.A cellular reactive carbonyl species (RCS), 4HNE, was significantly increased in diabetic hearts due to a diabetes-induced decrease in 4HNE detoxification by aldehyde dehydrogenase (ALDH) 2, a cardiac mitochondrial enzyme that metabolizes 4HNE. Therefore, hyperglycemia-induced 4HNE is critical for diabetes-mediated cardiotoxicity and we hypothesize that lowering 4HNE ameliorates diabetes-associated HFpEF. We fed a high-fat diet to ALDH2*2 mice, which have intrinsically low ALDH2 activity, to induce type-2 diabetes. …

Uab Voice Professor Releases New Album, Will Present Free Performance Sept. 19, Shannon Thomason

Browse All News

No abstract provided.

Professional Development Of Cataloguers In Electronic Era In Academic Libraries In Selected Private Universities, Osun State, Franca Ngeme, Grace Morenike Ajewole, Oluwole Banji Ajayi

Library Philosophy and Practice (e-journal)

Abstract

This paper examines professional development of cataloguers in electronic era in academic library in selected private universities, Osun state. The research was necessitated by the postulation that cataloguers competency depend on their professional development. Two research questions were drawn and the population of the study was made up of 8 cataloguers. Data was collected through questionnaire. The descriptive survey research method was adopted in the study. Findings revealed that cataloguers are faced with lack of organizational sponsorship to conference, seminar and workshop; it was shown that, they have challenges on the job training. The study further revealed that cataloguers …

Put Your Mind At Ease With These 7 Free Safety Resources, Staff

Browse All News

No abstract provided.

Uab Students Selected For Prestigious Gilman International Scholarship And Freeman-Asia Award, Staff

Browse All News

No abstract provided.

Coexistence Of Cutaneous Squamous Cell Carcinoma And Basal Cell Carcinoma In A Renal Transplant Recipient: A Case Report., Diana Voloshyna, Tanveer Ahamad Shaik, Sunita Shrestha, Ajmat Ansari, Faraz Saleem, Muhammad Abu Zar Ghaffari

Faculty and Staff Scholarship

In solid organ transplant patients, non-melanoma skin cancer remains a leading cause of mortality. The most common skin malignancies in solid organ transplant patients are squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). In organ transplant patients, SCC is 100 times more prevalent, and BCC is 10 times more prevalent than in the general population. Many risk factors for developing such malignancies are equivalent to those in the general population. However, in the transplant population, such cancers occur at an earlier age, act more aggressively, and often appear at multiple locations. Thus, assiduousness on the patient's part and healthcare …

Oct. 2, Be Dazzled By Lightwire Theater's "The Adventures Of Tortoise And Hare", Shannon Thomason

Browse All News

No abstract provided.

Aberrant Right Subclavian Artery Presenting As Upper Airway Obstruction And Dysphagia Lusoria, Abdul Aziz S. Siddiqui, Kazi Khan, Kidus Kebede

Aurora GME

No abstract provided.

Dialysis Induced Hypotension: A Rare Case Of Bilateral Simultaneous Non-Arteritic Anterior Ischemic Optic Neuropathy, Shahzaad Jahangier, Colleen Nichols

Aurora GME

No abstract provided.

Hemoptysis Following Subclavian Vein Puncture For Pacemaker Implantation, Brandon Bukovitz, Mohammed Premjee, Mouhammed Rihawi

Aurora GME

No abstract provided.

Vitamin B12 Deficiency As Unexpected Cause Of Hemolytic Anemia And Atypical Presentation Of Hepatocellular Adenoma, Andrew Gregory, Magdalena Flejsierowicz

Aurora GME

No abstract provided.

Hyperglycemia-Induced Osmotic Demyelination Syndrome In A Type 2 Diabetic With Stable Serum Sodium, Jesse Galuk, Ian Kuckelman, Ankoor Biswas

Aurora GME

No abstract provided.

Weight-Loss Supplement Induced Nstemi In The Setting Of Friedrich's Ataxia Cardiomyopathy, Jesse Galuk, Nicholas Beaudrie, Daniel R Harland

Aurora GME

No abstract provided.

Autoethnographic Memory Archive, K Parker, S Moore

School of Art, Design and Architecture

Part of the journal section, 'Choreographing the Archive', which highlights the visual evolution of one particular strand of screendance creation that focuses on choreographing and working with found and archival footage. The artists featured explore diverse notions of found gestures, found footage, family archives, contemporary news footage, as well as historic archival images.'Autoethnographic Memory Archive' features Father-land (2018), a 20-minute essay flm made collaboratively by Stuart Moore and Kayla Parker through an artist research residency hosted by the Nicosia Municipal Arts Centre (NiMAC) in Cyprus. The story of Nicosia unfolds through a montage of views of the fractured landscape of …

Infographic: Digital Copyright Laws And Online Teaching, Zoe Kaskamanidis

Teacher infographics

A new report has assessed whether copyright limitations for educational purposes are unfit for remote education through a legal analysis of copyright laws in 40 countries. This infographic shows the number of countries in the report for which the following online teaching scenarios are not legal.

Mutations In Bcor, A Co-Repressor Of Crx/Otx2, Are Associated With Early-Onset Retinal Degeneration, Maéva Langouët, Christine Jolicoeur, Awais Javed, Pierre Mattar, Micah D Gearhart, Mette Bertelsen, Nanna D Rendtorff, Karen Grønskov, Catherine Jespersgaard, Rui Chen, Zixi Sun, Hui Li, Najmeh Alirezaie, Jacek Majewski, Vivian J Bardwell, Ruifang Sui, Robert K Koenekoop, Michel Cayouette

Faculty, Staff and Student Publications

Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCOR), a Polycomb repressive complex 1 factor mutated in various cancers, is involved in photoreceptor degenerative diseases. Using proteomics and transcription assays, we report that BCOR interacts with the transcription factors CRX and OTX2 and reduces their ability to activate the promoters of photoreceptor-specific genes. CUT&RUN sequencing further shows that BCOR shares genome-wide binding profiles with CRX/OTX2, consistent with a general co-repression activity. We also identify missense …

Designing Optimal Convolutional Neural Network Architecture Using Differential Evolution Algorithm

Faculty, Staff and Student Publications

Convolutional neural networks (CNNs) are deep learning models used widely for solving various tasks like computer vision and speech recognition. CNNs are developed manually based on problem-specific domain knowledge and tricky settings, which are laborious, time consuming, and challenging. To solve these, our study develops an improved differential evolution of convolutional neural network (IDECNN) algorithm to design CNN layer architectures for image classification. Variable-length encoding is utilized to represent the flexible layer architecture of a CNN model in IDECNN. An efficient heuristic mechanism is proposed in IDECNN to evolve CNN architecture through mutation and crossover to prevent premature convergence during …

Decolonisation Of Curricula In Undergraduate Dental Education: An Exploratory Study, Kamran Ali, Jennie Winter, Oliver Webb, Daniel Zahra

Peninsula Dental School

AbstractAims To explore experiences and perceptions of students and staff regarding decolonisation of the curriculum in a dental undergraduate programme.Methods Participants were invited to respond to an online survey on decolonisation of the dental curriculum. The target population included current students on the Bachelor of Dental Surgery and Bachelor of Dental Therapy and Hygiene programmes, as well as dental staff at a university in the South West region of England. The common items for student and staff versions of the survey were focused on six themes: representation; content; peer engagement; assessment; language and communication; and culture. All responses were anonymous. …

Health Workers’ Documentation Process As A Prerequisite To The Integration Of Patient Care At A Regional Referral Hospital In Uganda, Grace Nakate, Mary Moleki, Ahmed Sarki, Valerie Fleming

School of Nursing & Midwifery, East Africa

Background: Integrated patient care is necessary for better care outcomes. Documentation enhances the integration of care; however, in the Ugandan setting, documentation of care is poor (e.g., omissions and incomplete records) and integration of patient care is not visible. This study presents a review of patient health records that was undertaken to understand documentation of care at a regional referral hospital in Eastern Uganda. This information will help in developing a documentation model to facilitate the integration of patient care in Uganda.

Methodology: This retrospective review involved 513 patient health records from the medical-surgical, pediatric, and obstetric/gynecological departments of Jinja …

Sleep, Sirtuin 1 And Alzheimer’S Disease: A Review, Mehrane Mehramiz, Tenielle Porter, Simon Laws, Stephanie R. Rainey-Smith

Research outputs 2022 to 2026

Sleep plays a major role in brain health, and cognition. Disrupted sleep is a well-described symptom of Alzheimer’s disease (AD). However, accumulating evidence suggests suboptimal sleep also increases AD risk. The deacetylase Sirtuin 1 (Sirt 1), encoded by the SIRT1 gene, impacts sleep via its relationship to wake-sleep neurotransmitters and somnogens. Evidence from animal and human studies supports a significant and complex relationship between sleep, Sirt 1/ SIRT1 and AD. Numerous hypotheses attempt to explain the critical impact of Sirt 1/ SIRT1 on wake- and sleep- promoting neurons, their related mechanisms and neurotransmitters. However, there is a paucity of studies …

Imm-Bcp-01, A Patient-Derived Anti-Sars-Cov-2 Antibody Cocktail, Is Active Across Variants Of Concern Including Omicron Ba.1 And Ba.2, Pavel A Nikitin, Suzanne M Scheaffer, Michael S Diamond, Et Al

2020-Current year OA Pubs

Monoclonal antibodies are an efficacious therapy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, rapid viral mutagenesis led to escape from most of these therapies, outlining the need for an antibody cocktail with a broad neutralizing potency. Using an unbiased interrogation of the memory B cell repertoire of patients with convalescent COVID-19, we identified human antibodies with broad antiviral activity in vitro and efficacy in vivo against all tested SARS-CoV-2 variants of concern, including Delta and Omicron BA.1 and BA.2. Here, we describe an antibody cocktail, IMM-BCP-01, that consists of three patient-derived broadly neutralizing antibodies directed at nonoverlapping surfaces …