Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 671191 - 671220 of 5207352

Full-Text Articles in Entire DC Network

Trends In Cornea Fellowship Applications And Applicant Characteristics: A San Francisco Match Analysis, Brittany C. Tsou, Ugochi T. Aguwa, Lubaina T. Arsiwala, Eleanor Burton, Kapil Mishra, Sidra Zafar, Fasika Woreta Sep 2022

Trends In Cornea Fellowship Applications And Applicant Characteristics: A San Francisco Match Analysis, Brittany C. Tsou, Ugochi T. Aguwa, Lubaina T. Arsiwala, Eleanor Burton, Kapil Mishra, Sidra Zafar, Fasika Woreta

Journal of Academic Ophthalmology

Abstract

Purpose We investigate trends in cornea fellowship positions filled over time and applicant characteristics associated with matching into cornea fellowship.

Methods Characteristics of cornea fellowship applicants were assessed using deidentified 2010 to 2017 San Francisco (SF) Match data. Publicly available SF Match cornea fellowship data including the number of participating programs, number of positions offered, number of positions filled, percentage of positions filled, and number of vacancies from 2014 to 2019 were also analyzed as data from 2010 to 2013 were unavailable.

Results From 2014 to 2019, the number of cornea fellowship programs increased by 11.3% (mean 2.3% per …


Impact Of Skeletal Muscle Loss During Conversion Therapy On Clinical Outcomes In Lavage Cytology Positive Patients With Gastric Cancer, Ping'an Ding, Peigang Yang, Li Yang, Chenyu Sun, Shuya Chen, Min Li, Scott Lowe, Honghai Guo, Yuan Tian, Yang Liu, Qun Zhao Sep 2022

Impact Of Skeletal Muscle Loss During Conversion Therapy On Clinical Outcomes In Lavage Cytology Positive Patients With Gastric Cancer, Ping'an Ding, Peigang Yang, Li Yang, Chenyu Sun, Shuya Chen, Min Li, Scott Lowe, Honghai Guo, Yuan Tian, Yang Liu, Qun Zhao

Student Publications

Background: The relationship between sarcopenia and clinical outcomes during conversion therapy in patients with lavage cytology positive gastric cancer (GC-CY1) remains unclear. This study aimed to investigate the impact of sarcopenia and skeletal muscle loss on the efficacy of conversion therapy, tumour response and survival in GC-CY1 patients.

Methods: Retrospective analysis of data from a prospective trial of conversion therapy conducted between April 2018 and August 2019 in patients with GC-CY1 (NCT03718624). Skeletal muscle index (SMI) was measured at the level of the third lumbar (L3) vertebra and the sarcopenia was defined using published cut-off points in all …


Standards-Aligned Math Curriculum, Student Demographics, And School Improvement: An Investigation Of Illinois’ Lowest-Performing K-8 Schools, Christine Paxson Sep 2022

Standards-Aligned Math Curriculum, Student Demographics, And School Improvement: An Investigation Of Illinois’ Lowest-Performing K-8 Schools, Christine Paxson

Theses and Dissertations

The purpose of this study was to provide a greater understanding of the broader characteristics of the lowest performing elementary and middle schools in Illinois, as little analysis of this data had been conducted. Furthermore, little to no research has explored the vertical and horizontal alignment of math curricula and its correlation to achievement scores. The results of the study suggest that the impact of Covid-19 has taken a toll on our K-12 students and teachers, as well as leaders. There is a higher percentage of principal turnover in the last six years, in schools summatively designated comprehensive, that have …


Nccec Schedule - Friday, Nccec Sep 2022

Nccec Schedule - Friday, Nccec

National Cross-Cultural Counseling & Education Conference for Research, Action & Change (2016-2024)

This schedule includes basic information about the presentations included in the Friday schedule for NCCEC 2022.


Arts & Humanities News, Georgia Southern University Sep 2022

Arts & Humanities News, Georgia Southern University

Arts & Humanities: News & Publications (2009-2023)

  • Georgia Poetry Circuit Presents Ashley M. Jones on November 10


The George-Anne Daily, Georgia Southern University Sep 2022

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Advancing Industrial Participation In Demand Response Within National Electricity Grids Through Systematic Asset Selection, Risk Assessment And Modelling Approaches, Alexander Brem Sep 2022

Advancing Industrial Participation In Demand Response Within National Electricity Grids Through Systematic Asset Selection, Risk Assessment And Modelling Approaches, Alexander Brem

Theses

Increasing the flexible capacity on national electricity grids will be key to maintain reliable control as the levels of renewables continue to increase annually. The industrial sector has been identified as being capable of contributing and potentially offering flexible capacities, following appropriate investigation. The aim of this thesis is to develop the knowledge, advance the engagement and encourage additional participation in national demand response programmes from the industrial sector to provide this flexibility. The potential within this sector, facilitated by the smart grid and demand response concepts is outlined, specifically detailing their benefits, driving factors and potential barriers as part …


Biden Approval Remains Mired In Low 40s In Nh; Majority Approve Of Fbi Search Of Trump's Home In Florida 9/23/2022, Unh Survey Center Sep 2022

Biden Approval Remains Mired In Low 40s In Nh; Majority Approve Of Fbi Search Of Trump's Home In Florida 9/23/2022, Unh Survey Center

All UNH Survey Center Polls

President Joe Biden continues to get low performance ratings in New Hampshire, particularly his handling of the economy. A small majority of Granite Staters approve of the FBI's decision to conduct a search of former President Donald Trump's home in Florida and few think that Trump's handling of classified material after his term in office has been appropriate.


Minutes Of Graduate College Committee On Curricula, September 23, 2022, University Of Northern Iowa. Graduate College Curriculum Committee. Sep 2022

Minutes Of Graduate College Committee On Curricula, September 23, 2022, University Of Northern Iowa. Graduate College Curriculum Committee.

Minutes - Graduate Curriculum Committee

Minutes of the committee that oversees the development of the curriculum of the University of Northern Iowa Graduate College.


The Impact Of Covid-19 On Secondary Victimization And Resiliency Following Sexual Assault, Elena Cantorna Sep 2022

The Impact Of Covid-19 On Secondary Victimization And Resiliency Following Sexual Assault, Elena Cantorna

Clinical Psychology Dissertations

Many individuals report negative experiences with the court system after experiencing a sexual assault (i.e., secondary victimization) and this leads to a belief that they are unable to cope with future stressors (i.e., resiliency). Furthermore, the COVID-19 pandemic negatively impacted individual’s lives and their overall well-being. In this dissertation, I examined a model predicting resiliency appraisals from positive experiences with the legal system, mediated by COVID-19 weekly metric case rate and the number of COVID-19 vaccines administered. Participants were 18 years and older, self-identified cis females, and were clients of a local legal advocacy clinic (N = 94) following …


2022-2023 Performance Forum - September 23, 2022, Jasmin Abdunazarova, Marina Machado, Moises Molina, Sheng Yuan Kuan, Daniel Guevara, Luis Pulido, Juan Diaz Quijano, Jeffrey Chapman, Kenton Campbell, Mark Severeniuk, Alexander Walden, Miguelangel Garcia Marquez, Fabiola Parra Sep 2022

2022-2023 Performance Forum - September 23, 2022, Jasmin Abdunazarova, Marina Machado, Moises Molina, Sheng Yuan Kuan, Daniel Guevara, Luis Pulido, Juan Diaz Quijano, Jeffrey Chapman, Kenton Campbell, Mark Severeniuk, Alexander Walden, Miguelangel Garcia Marquez, Fabiola Parra

Performance Forum

No abstract provided.


Predicting At-Risk Opioid Use Three Months After Ed Visit For Trauma: Results From The Aurora Study, Brittany E. Punches, Uwe Stolz, Caroline E. Freiermuth, Rachel M. Ancona, Samuel A. Mclean, Stacey L. House, Francesca L. Beaudoin, Xinming An, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey Jr., Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Michael C. Kurz, Nina T. Gentile, Meghan E. Mcgrath, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O'Neil, Leon D. Sanchez, Steven E. Bruce, Robert H. Pietrzak, Jutta Joormann, Deanna M. Barch, Diego A. Pizzagalli, Jordan W. Smoller, Beatriz Luna, Steven E. Harte, James M. Elliott, Ronald C. Kessler, Kerry J. Ressler, Karestan C. Koenen, Michael S. Lyons Sep 2022

Predicting At-Risk Opioid Use Three Months After Ed Visit For Trauma: Results From The Aurora Study, Brittany E. Punches, Uwe Stolz, Caroline E. Freiermuth, Rachel M. Ancona, Samuel A. Mclean, Stacey L. House, Francesca L. Beaudoin, Xinming An, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey Jr., Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Michael C. Kurz, Nina T. Gentile, Meghan E. Mcgrath, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O'Neil, Leon D. Sanchez, Steven E. Bruce, Robert H. Pietrzak, Jutta Joormann, Deanna M. Barch, Diego A. Pizzagalli, Jordan W. Smoller, Beatriz Luna, Steven E. Harte, James M. Elliott, Ronald C. Kessler, Kerry J. Ressler, Karestan C. Koenen, Michael S. Lyons

Department of Emergency Medicine Faculty Papers

OBJECTIVE: Whether short-term, low-potency opioid prescriptions for acute pain lead to future at-risk opioid use remains controversial and inadequately characterized. Our objective was to measure the association between emergency department (ED) opioid analgesic exposure after a physical, trauma-related event and subsequent opioid use. We hypothesized ED opioid analgesic exposure is associated with subsequent at-risk opioid use.

METHODS: Participants were enrolled in AURORA, a prospective cohort study of adult patients in 29 U.S., urban EDs receiving care for a traumatic event. Exclusion criteria were hospital admission, persons reporting any non-medical opioid use (e.g., opioids without prescription or taking more than prescribed …


Case Report: The Promising Application Of Dynamic Functional Connectivity Analysis On An Individual With Failed Back Surgery Syndrome, Jingya Miao, Isaiah Ailes, Laura Krisa, Kristen Fleming, Devon Middleton, Kiran Talekar, Peter Natale, Feroze B. Mohamed, Kevin Hines, Caio M. Matias, Mahdi Alizadeh Sep 2022

Case Report: The Promising Application Of Dynamic Functional Connectivity Analysis On An Individual With Failed Back Surgery Syndrome, Jingya Miao, Isaiah Ailes, Laura Krisa, Kristen Fleming, Devon Middleton, Kiran Talekar, Peter Natale, Feroze B. Mohamed, Kevin Hines, Caio M. Matias, Mahdi Alizadeh

Department of Neurosurgery Faculty Papers

Failed back surgery syndrome (FBSS), a chronic neuropathic pain condition, is a common indication for spinal cord stimulation (SCS). However, the mechanisms of SCS, especially its effects on supraspinal/brain functional connectivity, are still not fully understood. Resting state functional magnetic resonance imaging (rsfMRI) studies have shown characteristics in patients with chronic low back pain (cLBP). In this case study, we performed rsfMRI scanning (3.0 T) on an FBSS patient, who presented with chronic low back and leg pain following her previous lumbar microdiscectomy and had undergone permanent SCS. Appropriate MRI safety measures were undertaken to scan this subject. Seed-based functional …


Bfs News Online, Georgia Southern University Sep 2022

Bfs News Online, Georgia Southern University

Art: News & Publications (2008-2023)

  • Pease’s Work Exhibited in Chianciano Biennale in Italy


Transcriptome Signatures Of Wastewater Effluent Exposure In Larval Zebrafish Vary With Seasonal Mixture Composition In An Effluent-Dominated Stream, Emma B. Meade, Luke R. Iwanowicz, Nicklaus Neureuther, Gregory H. Lefevre, Dana W. Kolpin, Hui Zhi, Shannon M. Meppelink, Rachael F. Lane, Angela Schmoldt, Aurash Mohaimani, Olaf Mueller, Rebecca D. Klaper Sep 2022

Transcriptome Signatures Of Wastewater Effluent Exposure In Larval Zebrafish Vary With Seasonal Mixture Composition In An Effluent-Dominated Stream, Emma B. Meade, Luke R. Iwanowicz, Nicklaus Neureuther, Gregory H. Lefevre, Dana W. Kolpin, Hui Zhi, Shannon M. Meppelink, Rachael F. Lane, Angela Schmoldt, Aurash Mohaimani, Olaf Mueller, Rebecca D. Klaper

United States Geological Survey: Staff Publications

Wastewater treatment plant (WWTP) effluent-dominated streams provide critical habitat for aquatic and terrestrial organisms but also continually expose them to complex mixtures of pharmaceuticals that can potentially impair growth, behavior, and reproduction. Currently, few biomarkers are available that relate to pharmaceutical-specific mechanisms of action. In the experiment reported in this paper, zebrafish (Danio rerio) embryos at two developmental stages were exposed to water samples from three sampling sites (0.1 km upstream of the outfall, at the effluent outfall, and 0.1 km below the outfall) during base-flow conditions from two months (January and May) of a temperate-region effluent-dominated stream …


Spatial Patterns Of Woody Plant Encroachment In A Temperate Grassland, Dillon T. Fogarty, Robert B. Peterson, Dirac Twidwell Sep 2022

Spatial Patterns Of Woody Plant Encroachment In A Temperate Grassland, Dillon T. Fogarty, Robert B. Peterson, Dirac Twidwell

Department of Agronomy and Horticulture: Faculty Publications

Context Woody encroachment is the process whereby grasslands transition to a woody-dominated state. This process is a global driver of grassland decline and is ultimately the outcome of increased woody plant recruitment in grasslands. Yet, little is known about how recruitment distances structure spatial patterns of encroachment.

Objectives Here, we develop a recruitment curve to describe the scatter of woody plant recruitment around seed sources and examine how this structures spatial patterns of encroachment.

Methods We developed a recruitment curve for Juniperus virginiana using an encroachment dataset that captures spread from tree plantings into treeless grassland sites in the Nebraska …


Artificial Intelligence In Civil Infrastructure Health Monitoring—Historical Perspectives, Current Trends, And Future Visions, Tarutal Ghosh Mondal, Genda Chen Sep 2022

Artificial Intelligence In Civil Infrastructure Health Monitoring—Historical Perspectives, Current Trends, And Future Visions, Tarutal Ghosh Mondal, Genda Chen

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Over the past 2 decades, the use of artificial intelligence (AI) has exponentially increased toward complete automation of structural inspection and assessment tasks. This trend will continue to rise in image processing as unmanned aerial systems (UAS) and the internet of things (IoT) markets are expected to expand at a compound annual growth rate of 57.5% and 26%, respectively, from 2021 to 2028. This paper aims to catalog the milestone development work, summarize the current research trends, and envision a few future research directions in the innovative application of AI in civil infrastructure health monitoring. A blow-by-blow account of the …


Effectiveness And Safety Of Apixaban Vs Warfarin Among Venous Thromboembolism Patients At High-Risk Of Bleeding, Alexander T. Cohen, Janvi Sah, A. D. Dhamane, Theodore Lee, Lisa Rosenblatt, Patrick Hlavacek, Birol Emir, Allison V. Keshishian, Huseyin Yuce, Xuemei Luo Sep 2022

Effectiveness And Safety Of Apixaban Vs Warfarin Among Venous Thromboembolism Patients At High-Risk Of Bleeding, Alexander T. Cohen, Janvi Sah, A. D. Dhamane, Theodore Lee, Lisa Rosenblatt, Patrick Hlavacek, Birol Emir, Allison V. Keshishian, Huseyin Yuce, Xuemei Luo

Publications and Research

This study evaluated effectiveness and safety of apixaban versus warfarin among venous thromboembolism patients at high-risk of bleeding (defined as having at least one of the following bleeding risk factors: ≥75 years; used antiplatelet, NSAIDs, or corticosteroids; had prior gastrointestinal bleeding or gastrointestinal-related conditions; late stage chronic kidney disease). Adult venous thromboembolism patients initiating apixaban or warfarin with ≥1 bleeding risk factor were identified from Medicare and four commercial claims databases in the United States. To balance characteristics between apixaban and warfarin patients, stabilized inverse probability treatment weighting was conducted. Cox proportional hazards models were used to estimate the risk …


Use Of Electronic Information Resources By Postgraduate Students Of Faculty Of Education In Imo State University, Owerri Library, Linda Ijeoma Uwandu Sep 2022

Use Of Electronic Information Resources By Postgraduate Students Of Faculty Of Education In Imo State University, Owerri Library, Linda Ijeoma Uwandu

Library Philosophy and Practice (e-journal)

The study examined the use of electronic information resources by postgraduate students of Faculty of Education in Imo State University, Owerri Library. Four research questions guided the study. Survey research design was adopted in carrying out this study. The population of the study is 181 postgraduate students of Faculty of Education in Imo State University, Owerri. The sample for the study was 181 postgraduate students. Using census sampling technique, the entire population was adopted as sample for the study. Online questionnaire was used to collect data for this study and was rated using the four-point scale. A total of 135 …


The Development And Growth Of Cardio-Oncology Or Onco-Cardiology, Bernard Man Yung Cheung, Chu Pak Lau Sep 2022

The Development And Growth Of Cardio-Oncology Or Onco-Cardiology, Bernard Man Yung Cheung, Chu Pak Lau

Journal of the Hong Kong College of Cardiology

No abstract provided.


The Social, Political, And Psychological Extensions Of Expatriation Through Views Of Place, Ioannis Galanopoulos Papavasileiou Sep 2022

The Social, Political, And Psychological Extensions Of Expatriation Through Views Of Place, Ioannis Galanopoulos Papavasileiou

All Works

The project Views from Expatria: Photographing Place and the Self in Transience investigates the intersection between photography, expatriation, and an expanded context of human migrations. Expatriates, transient skilled workers, within today’s ease of mobility for work can easily lose sight of “home.” Recurrent transits and travels away from home are associated with the everyday experience of expatriates. Although there are many benefits associated with working abroad, these do not come without challenges for the expatriated individual. My creative work Photographing Place and Self in transience and this article reveal the social, political, and psychological complexities associated with the global phenomenon …


Uab Freshman Pre-Med Student Shi Recognized As A 2022 Presidential Scholar, Alicia Rohan Sep 2022

Uab Freshman Pre-Med Student Shi Recognized As A 2022 Presidential Scholar, Alicia Rohan

Browse All News

No abstract provided.


Uab Cardiovascular Institute Is Nationally Recognized For Its Commitment To Providing High-Quality Heart Care, Tehreem Khan Sep 2022

Uab Cardiovascular Institute Is Nationally Recognized For Its Commitment To Providing High-Quality Heart Care, Tehreem Khan

Browse All News

No abstract provided.


Irreversible Electroporation For Recurrent Pelvic Metastases: Case Series And Literature Review., Duncan A. Stevens, Jeffrey H. Savin, Brett J. Friedman, Michael A. Savin Sep 2022

Irreversible Electroporation For Recurrent Pelvic Metastases: Case Series And Literature Review., Duncan A. Stevens, Jeffrey H. Savin, Brett J. Friedman, Michael A. Savin

Conference Presentation Abstracts

Purpose: Irreversible electroporation (IRE) is a nonthermal ablative technique that has potential safety advantages over thermal ablation in the treatment of tumors near critical structures. It creates an electrical field which forms permanent nanopores in the membranes of cells and triggers apoptosis. This case series reviews three patients with pelvic metastases from colorectal cancer treated with IRE.

Material and Methods: Two patients had rectal cancer and one sigmoid colon cancer. The mean age was 55 years and there were two males and one female. Thermal ablation was contraindicated due to proximity to ureter, bladder, bowel, and/or sciatic or lumbosacral nerves. …


Assessing The Effect Of Four Types Of Direct Mail Messages To Promote The Uptake Of Residential Lead Remediation Funds, H. Okatch, B. Nkala, J. Beltrami, E. Poy, D. Parmer, J. Nkala, F. Olawole Sep 2022

Assessing The Effect Of Four Types Of Direct Mail Messages To Promote The Uptake Of Residential Lead Remediation Funds, H. Okatch, B. Nkala, J. Beltrami, E. Poy, D. Parmer, J. Nkala, F. Olawole

College of Population Health Faculty Papers

Objective

To examine the efficacy of direct mailing using four types of messaging on promoting the uptake of residential lead remediation (RLR) funds in Lancaster, PA, USA.

Study design

We designed a quasi-experiment to assess the effect of 4 RLR messages sent to households in Lancaster, PA by direct mail between September and December 2020: a brief flyer (F); a detailed brochure + the flyer (BF); a health infographic + the flyer (IF); and an application form + the flyer (AFF).

Methods

Mailers were sent to addresses in four census tracts; each census tract received a different message. Both English …


Non-Sedative Cortical Eeg Signatures Of Allopregnanolone And Functional Comparators, Peter M Lambert, Richard Ni, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, Steven Mennerick Sep 2022

Non-Sedative Cortical Eeg Signatures Of Allopregnanolone And Functional Comparators, Peter M Lambert, Richard Ni, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, Steven Mennerick

2020-Current year OA Pubs

Neurosteroids that positively modulate GABA


High-Yield Webinar Engagement Strategies And Teacher Candidate Professional Learning, Meghan Cosier, Sara Morgan, Audri Sandoval Gomez Sep 2022

High-Yield Webinar Engagement Strategies And Teacher Candidate Professional Learning, Meghan Cosier, Sara Morgan, Audri Sandoval Gomez

Education Faculty Articles and Research

In response to the COVID-19 school closures in both K-12 and higher education, a group of education partners in the United States collaborated to offer a statewide webinar series, 12 webinars in total, to support preservice teachers as they worked to complete their clinical hour requirements. The webinars and extension activities provided via Padlets covered topics associated with best practices and related to credential requirements such as applying universal design for learning and differentiating instruction. This study explored the perceptions of 248 preservice teachers regarding the virtual professional learning format and extension activities, as well as what professional learning they …


Micromorphology And Histology Of The Secretory Apparatus Of Diospyros Villosa (L.) De Winter Leaves And Stem Bark, Ot Adu, Yougasphree Naidoo, Ts Adu, Venkataramegowda Sivaram, Yaser Hassan Dewir, Hail Rihan Sep 2022

Micromorphology And Histology Of The Secretory Apparatus Of Diospyros Villosa (L.) De Winter Leaves And Stem Bark, Ot Adu, Yougasphree Naidoo, Ts Adu, Venkataramegowda Sivaram, Yaser Hassan Dewir, Hail Rihan

School of Biological and Marine Sciences

Diospyros villosa is a perennial species prominently acknowledged for its local medicinal applications. The native utilisation of this species in traditional medicine may be ascribed to the presence of secretory structures and their exudate (comprised of phytochemicals). However, the morphological nature and optical features of the secretory structures in D. villosa remain largely unclear. This study was directed to ascertain the occurrence and adaptive features of structures found within the leaves and stem bark of D. villosa using light and electron microscopy techniques. The current study notes the existence of trichomes, and other secretory structures were noted. SEM indicated the …


Longitudinal Study Of ‘Retraining’ Non-Maths Specialist Teachers To Become Capable, Confident Teachers Of Mathematics, Naomi Sani, David Burghes Sep 2022

Longitudinal Study Of ‘Retraining’ Non-Maths Specialist Teachers To Become Capable, Confident Teachers Of Mathematics, Naomi Sani, David Burghes

Plymouth Institute of Education

One of the key problems to be solved in mathematics education in England is that the demand for mathematics teachers is far in excess of the supply. Acknowledging that there are simply too few mathematics teachers, the UK government has invested significantly in retraining programmes. These programmes ‘retrain’ out-of-field teachers, that is, teachers of other subjects or from other phases, to teach secondary mathematics. The increased mathematical demand of the reformed GCSE courses coupled with the expectation that most post-16 students will engage with some mathematics (studying for A and AS levels, a Core Maths qualification or re-sitting GCSE) means …


To Bind Or Not To Bind: Cistromic Reprogramming In Prostate Cancer Sep 2022

To Bind Or Not To Bind: Cistromic Reprogramming In Prostate Cancer

Faculty, Staff and Student Publications

The term "cistrome" refers to the genome-wide location of regulatory elements associated with transcription factor binding-sites. The cistrome of key regulatory factors in prostate cancer etiology are substantially reprogrammed and altered during prostatic transformation and disease progression. For instance, the cistrome of the androgen receptor (AR), a ligand-inducible transcription factor central in normal prostate epithelium biology, is directly impacted and substantially reprogrammed during malignant transformation. Accumulating evidence demonstrates that additional transcription factors that are frequently mutated, or aberrantly expressed in prostate cancer, such as the pioneer transcription factors Forkhead Box A1 (FOXA1), the homeobox protein HOXB13, and the GATA binding …