Digital Commons Network^™

Chronic Red Cell Exchange In Sickle Cell Patients With Iron Overload May Not Affect Mortality, Yi Yuan Zhou, Hollie M. Reeves, Robert W. Maitta

Faculty Scholarship

Sickle cell disease (SCD) is an inherited blood disorder that affects ~100,000 Americans (1, 2). In SCD, red blood cells (RBC) containing aberrant sickle hemoglobin (HgbS) become sickle-shaped at low oxygen tension and stick together leading to obstructed blood flow. The resulting decrease in tissue oxygenation causes chronic complications such as vasculo-occlusive pain crises among others that require frequent hospitalizations (3). Chronic RBC transfusions play a prominent role in the treatment of this disease by improving oxygenation through addition of normal RBC and dilution of RBC containing HgbS (4, 5). However, the major disadvantage of management with simple transfusion is …

Comparative Study Of High-Performance Thin-Layer Chromatography And Antioxidant Potential Of Hydrocotyle Asiatica Mother Tincture Used In Homoeopathy, Rakhi Mishra, Binit Kumar Dwivedi, Deepshikha Gupta

Indian Journal of Research in Homoeopathy

Background: Hydrocotyle asiatica has a therapeutic significance in the Indian system of medicine due to its rich antioxidant activity. In Homoeopathy, Hydrocotyle asiatica is used for the treatment of jaundice, skin diseases, dropsy, elephantiasis, leprosy, gonorrhea, leucorrhea, and nervous debility. It contains the abundant triterpene glycoside Asiatic acid which shows cytotoxic activity on cancer cells. Its homoeopathic mother tincture is a major source of antioxidant compounds, which is responsible for its overall pharmacological activity.

Objectives: This study was done to evaluate antioxidant activity and High-Performance Thin-Layer Chromatography study of Hydrocotyle asiatica in-house homoeopathic mother tincture and market samples. …

Cholesterol Lowering Activity Of Homoeopathic Preparations Of Colchicum Autumnale – An In Vitro Study, Nithya T, Mansoor Ali Kr, Sheeba Veluthoor, U S Jijith, P Sithara Perveen, Afiya Alloor, Shijil V K

Indian Journal of Research in Homoeopathy

Background: Total cholesterol content of erythrocyte membranes plays a critical role in atherosclerotic plaque progression and instability. Several homoeopathic medicines are known to have a significant role in the control of hyperlipidaemia. Colchicum autumnale is a plant remedy used mainly for gout, but also for hyperlipidaemia.

Objectives: This is a study to assess the in vitro anti-cholesterol action of the Colchicum autumnale (Colch. at.) on the erythrocyte membrane. Materials and

Methods: The study was conducted using a hyperlipidaemic blood sample which was divided into eight parts. Six different potencies of Colch. at. were tested, and two controls, …

Homoeopathy In The Management Of Chronic Kidney Disease – A Narrative Review, Supriya Singh, Varanasi Roja, Khushboo Garg, Nisha Sehrawat, Jyotika Bhatti, Abhijit Chakma

Indian Journal of Research in Homoeopathy

Background: Chronic kidney disease (CKD) is the third fastest-growing cause of death around the world and is projected to become the fifth most common cause of years of life lost worldwide by 2040.

Objective: This review was done to explore the strengths of homoeopathy in the management of CKD through pre-clinical, clinical and anecdotal evidence.

Methods: A search was made for homoeopathic management of CKD in PubMed, Central Council for Research in Homoeopathy e-library, AYUSH Research Portal, EMBASE and Google Scholar. The basic search terms included ‘Homoeopathy’ or ‘homoeopathic drugs’, ‘ESRD’, ‘CRF’, ‘CKD’ and ‘Bright’s disease’. No …

Nephrotic Syndrome Treated With Homoeopathy: An Evidence-Based Case-Report, Punam Kumari, Renu Verma

Indian Journal of Research in Homoeopathy

Introduction: Nephrotic syndrome (NS) is a glomerular disorder characterised by peripheral oedema, heavy proteinuria and hypoalbuminemia, often hyperlipidaemia. Patients generally present with oedema and fatigue. Complementary and alternative therapies have been widely used in the treatment of NS. The homoeopathic treatment for NS could be a safer approach to treating the disease.

Case Summary: This is the case of a 32-year-old man who presented with NS with membranous nephropathy and was successfully managed with individualised homoeopathic medicine, Natrium Sulphuricum over 1 year. The case was followed up with documentation of clinical symptoms and investigation reports findings. Changes in …

Polycystic Ovarian Syndrome With Endometrial Hyperplasia And Uterine Fibroids Treated With Homoeopathy: A Case Report, Vaishali Shinde

Indian Journal of Research in Homoeopathy

Introduction: Any circumstance that alters the balance of oestrogen and progesterone leads to excessive, prolonged estrogenic stimulation, or preventing the counteracting effects of progesterone causing various pathological conditions in the reproductive system, as a result. Women with polycystic ovarian syndrome (PCOS) have mostly anovulatory cycles and low serum progesterone levels. Endometrial hyperplasia is most often due to excess oestrogen without progesterone. The clinical significance of chronic oestrogen secretion is an increased risk of endometrial hyperplasia. A striking feature of uterine fibroids (UFs) is their dependency on the ovarian oestrogen and progesterone. Existing treatments are mostly directed at the symptoms …

Obituary : Prof. Emeritus Dr. Girendra Pal, Subhash Kaushik, Praveen Oberai, Nidhi Mahajan, Chetna Deep Lamba

Indian Journal of Research in Homoeopathy

The death of legendary and philanthropist Homoeopath Dr. Girendra Pal which occurred in Jaipur on 24th August 2022, will be mourned by all Homoeopathic fraternity and his beloved patients, family and friends. He practiced and popularised homoeopathy in Rajasthan and is rightly known as Father of Homoeopathy in Rajasthan.

Research Highlights, Shweta Singh, Pooja Kumari

Indian Journal of Research in Homoeopathy

Research Highlights

Collegiate Recovery Programs Serving As An Opportunity For Student Affairs, Marium Waqar

Theses and Dissertations

The purpose of this study was to investigate the current Collegiate Recovery Program (CRP) at Rowan University and the effects it had on the recovery student population. The study was designed to ask questions that would yield results about the effectiveness of the current CRP on Rowan's campus. Previous research indicates a need for more awareness about CRPs, and professionals in higher education need to be knowledgeable about students in recovery and their invisible disability. Findings suggest some Rowan students in recovery do not feel supported on campus, but many of them are not even aware of the resources that …

Sociocultural And Demographic Drivers Of Latino Population Health In New York State, Marc A. Garcia, Mara G. Sheftel, Adriana M. Reyes, Catherine Garcia

Population Health Research Brief Series

Latinos are the largest racial/ethnic minority group in the United States and are among the fastest-growing populations in New York State. However, there is variation across Latino sub-groups in educational attainment, income, and access to health insurance. This research brief explores the diversity within the Latino population living in New York State and describes inequities in key sociocultural and demographic drivers of Latino population health.

Usa Health Insider Newsletter - September 27, 2022, Bernell Dorrough, Marie Katz

USA Health Insider Newsletter

The USA Health Insider newsletter for September 27, 2022. The contents include:

• COVID Status Effective Sept. 22, 2022: Green Zone
• USA Comprehensive Sickle Cell Center Named for Johnson Haynes, Jr., M.D.
• “The End of an Era”
• Singh Appointed to BCRFA Medical Advisory Council
• MCI Staffer Consults on CDC Campaign
• Employees Have Java with Jo
• Game Day T-shirts Available Next Week
• Faculty Members Needed for Academic Coaching
• Register Now: Paddle the Escatawpa River CME Conference
• Watch Us Grow: September 27, 2022
• In the News: September 27, 2022
• FOX10 to Focus on Annual Checkups
• The Doctor Is In to Feature Urologist
• USA …

Perseverance: Turning Trials Into Triumphs, Erin Garrett

University of Mississippi News

Economics and public policy leadership major refuses to accept status quo

The Role Of The Individual Will In The Civil And Commercial Procedures Law As A New Source Of The Procedural Law: An Original And Analytical Study In The Omani Civil And Commercial Procedures Law, Ali Abouattia Heikal

Sultan Qaboos University Legal Studies Journal

This study sought to identify the role of individual will in procedural law. Therefore, it employed the descriptive approach of analyzing legal texts in which the procedural law related the application of its rules to the will of the opponents and attempted to root these texts. The paper discussed the topic in two sections; the role of the individual will in the Civil Transactions Law and the Procedural Law. The study concluded that individuals will is considered another source of the commercial and civil procedures law. To illustrate, some rules in the procedural law cannot operate to their full potential …

Sources Of Solidarity In Guarantee According To Omani Law: A Comparative Study, Mohamed Ibrahim Bendari

Sultan Qaboos University Legal Studies Journal

A solidarity guarantee is a type of guarantee in which the guarantor loses the reserve status of the debtor's commitment while their obligations remain subsidiary to the debtor, and as a result, it is not permissible for the guarantors to pay in installments, stripping, or claim them before claiming the debtor; it is, therefore, harsher than a simple guarantee. The solidarity guarantee is historically earlier than the simple guarantee because Roman law defined it in its early ages. It is also widely known in Islamic jurisprudence. Although the general rule is that solidarity is not supposed to be in guarantees, …

Unlawful Act Having A Continuing Character In The Context Of State Responsibility, Abdullah Elhabeeb Elmahjoub

Sultan Qaboos University Legal Studies Journal

Objective State responsibility is based on two legal aspects; first, committing an internationally unlawful act by a state contrary to an international obligation; and second, the unlawful act is attributable to the State concerned. Specific and concrete damages are not required for the allocation of international responsibility to a State. Given these elements, the present article entitled “Unlawful act having a continuing character in the context of State responsibility” deals with the legal issues concerning the question of a breach of an international obligation that is in a state of continuity since it began from the first place without coming …

Waqf In Malaysia:The Development Of Legal And Institutional Framework, Fares Djafri, Mohamad Akram Laldin, Sharifah Zubaidah Syed Abdul Kader

Sultan Qaboos University Legal Studies Journal

Awqaf properties in Malaysia have evolved over the years from being in the nature of consumptive immoveable properties used for religious purposes like madrasahs and mosques into productive and mixed-use type real estate properties like hotels, office buildings and commercial type properties. The regulatory and legal frameworks have played a vital role in the evolution of waqf sector and its management through the State of Islamic Religious Councils (SIRCs), the Department of Waqf and Hajj (JAWHAR) and Yayasan Waqaf Malaysia (YWM). In fact, waqf in Malaysia operates under three separate laws, namely: Islamic Law, Federal Territory Act or State Enactments …

Local Bounds For Singular Brascamp–Lieb Forms With Cubical Structure, Polona Durcik, Lenka Slavíková, Chrisoph Thiele

Mathematics, Physics, and Computer Science Faculty Articles and Research

We prove a range of L^p bounds for singular Brascamp-Lieb forms with cubical structure. We pass through sparse and local bounds, the latter proved by an iteration of Fourier expansion, telescoping, and the Cauchy-Schwarz inequality. We allow 2^m−1 < p ≤ ∞ with m the dimension of the cube, extending an earlier result that required p = 2^m. The threshold 2^m−1 is sharp in our theorems.

You Can Always Count On A Dog To Make Your Day A Little Better, Rhianwen Watkins

Digital Edition

An independent student produced newspaper from the University of New Hampshire.

Transmission Roles Of Symptomatic And Asymptomatic Covid-19 Cases: A Modelling Study, Jianbin Tan, Yang Ge, Leonardo Martinez, Jimin Sun, Changwei Li, Adrianna Westbrook, Enfu Chen, Jinren Pan, Yang Li, Wei Cheng, Feng Ling, Zhinping Chen, Ye Shen, Hui Huang

Faculty Publications

Coronavirus disease 2019 (COVID-19) asymptomatic cases are hard to identify, impeding transmissibility estimation. The value of COVID-19 transmissibility is worth further elucidation for key assumptions in further modelling studies. Through a population-based surveillance network, we collected data on 1342 confirmed cases with a 90-days follow-up for all asymptomatic cases. An age-stratified compartmental model containing contact information was built to estimate the transmissibility of symptomatic and asymptomatic COVID-19 cases. The difference in transmissibility of a symptomatic and asymptomatic case depended on age and was most distinct for the middle-age groups. The asymptomatic cases had a 66.7% lower transmissibility rate than symptomatic …

Arkansas State University Wind Ensemble, September 27th, Arkansas State University Department Of Music

Performance Programs

No abstract provided.

Mgrre_Thinsections_05_A_33, Mgrre

Thin Sections

No abstract provided.

Recent Emergence Of Bovine Coronavirus Variants With Mutations In The Hemagglutinin-Esterase Receptor Binding Domain In U.S. Cattle, Aspen M. Workman, Tara G. Mcdaneld, Gregory P. Harhay, Subha Das, John Dustin Loy, Benjamin M. Hause

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. The balance of the opposing activities of the surface spike (S) and hemagglutinin-esterase (HE) glycoproteins controls BCoV avidity, which is critical for interspecies transmission and host adaptation. Here, 78 genomes were sequenced directly from clinical samples collected between 2013 and 2022 from cattle in 12 states, primarily in the Midwestern U.S. Relatively little genetic diversity was observed, with genomes having >98% nucleotide identity. Eleven isolates collected between 2020 and 2022 from four states (Nebraska, Colorado, California, and Wisconsin) contained a …

Just What "Doc" Ordered, Tori Miller

Materials from the University of Dayton Magazine Website

From one Catholic school to another, how a high school guidance counselor has helped recruit University of Dayton students for years.

Do Local And World Covid-19 Media Coverage Drive Stock Markets? Time-Frequency Analysis Of Brics, Ahmed Bossman, Tamara Teplova, Zaghum Umar

All Works

The role of media coverage as a proxy for investor sentiments has led to the assessments of the impact of COVID-19 media coverage on financial markets. To determine how both local and global media coverage affect financial markets differently, we investigate this issue from the perspective of top emerging markets, BRICS (i.e., Brazil, Russia, India, China, and South Africa). With datasets covering January 2020 to March 2022, we employ the wavelet coherence technique on two major subsamples, viz. initial outbreak year sample and the “new normal” era sample. Our findings demonstrate the leading role of BRICS equities in the initial …

Sars-Cov-2, Long Covid, Prion Disease And Neurodegeneration, Yuhai Zhao, Vivian R. Jaber, Walter J. Lukiw

School of Medicine Faculty Publications

No abstract provided.

Non-Communicable Diseases: How Can Homoeopathy Contribute?, Subhash Kaushik

Indian Journal of Research in Homoeopathy

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Homoeopathic Management Of Polycystic Ovarian Syndrome – A Case Series, Sonia Raizada

Indian Journal of Research in Homoeopathy

Introduction: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in females of the reproductive age group. It is characterised by menstrual irregularities, enlarged ovaries, infertility, high levels of male hormones, excess hair on the face and body, acne and obesity. PCOS can result from abnormal function of the hypothalamic-pituitary-ovarian axis. Women with PCOS have an increased risk of diabetes, high blood pressure, heart disease and endometrial cancer.

Case Summary: A case series of seven PCOS patients treated with indicated constitutional homoeopathic medicines at Nehru Homoeopathic Medical College and Hospital, New Delhi, India, is presented here. Overall improvement …

Enhanced Membrane Binding Of Oncogenic G Protein Αqq209l Confers Resistance To Inhibitor Ym-254890, Clinita E. Randolph, Morgan B. Dwyer, Jenna L. Aumiller, Alethia J. Dixon, Asuka Inoue, Patrick Osei-Owusu, Philip B. Wedegaertner

Department of Biochemistry and Molecular Biology Faculty Papers

Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCRs) to intracellular signaling pathways. They can also function independently of GPCR activation upon acquiring mutations that prevent GTPase activity and result in constitutive signaling, as occurs with the αqQ209L mutation in uveal melanoma. YM-254890 (YM) can inhibit signaling by both GPCR-activated WT αq and GPCR-independent αqQ209L. Although YM inhibits WT αq by binding to αq-GDP and preventing GDP/GTP exchange, the mechanism of YM inhibition of cellular αqQ209L remains to be fully understood. Here, we show that YM promotes a subcellular redistribution of αqQ209L from the plasma membrane (PM) to the cytoplasm. …

Updates On Insect Pests Of Eastern White Pine, William H. Livingston

UNH Cooperative Extension

No abstract provided.

White Pine Management In Maine, Bob Seymour

UNH Cooperative Extension

No abstract provided.