Digital Commons Network^™

Aging After Stroke: How To Define Post-Stroke Sarcopenia And What Are Its Risk Factors?, Aila Malik, Hulin Wu, Walter R Frontera

Faculty, Staff and Student Publications

BACKGROUND: Sarcopenia, generally described as "aging-related loss of skeletal muscle mass and function", can occur secondary to a systemic disease.

AIM: This project aimed to study the prevalence of sarcopenia in chronic ambulatory stroke survivors and its associated risk factors using the two most recent diagnostic criteria.

DESIGN: A cross-sectional observational study.

SETTING: A scientific laboratory.

POPULATION: Chronic stroke.

METHODS: Twenty-eight ambulatory chronic stroke survivors (12 females; mean age=57.8±11.8 years; time after stroke=76±45 months), hand-grip strength, gait speed, and appendicular skeletal muscle mass (ASM) were measured to define sarcopenia. Risk factors, including motor impairment and spasticity, were identified using regression …

Netbce: An Interpretable Deep Neural Network For Accurate Prediction Of Linear B-Cell Epitopes

Faculty, Staff and Student Publications

Identification of B-cell epitopes (BCEs) plays an essential role in the development of peptide vaccines and immuno-diagnostic reagents, as well as antibody design and production. In this work, we generated a large benchmark dataset comprising 124,879 experimentally supported linear epitope-containing regions in 3567 protein clusters from over 1.3 million B cell assays. Analysis of this curated dataset showed large pathogen diversity covering 176 different families. The accuracy in linear BCE prediction was found to strongly vary with different features, while all sequence-derived and structural features were informative. To search more efficient and interpretive feature representations, a ten-layer deep learning framework …

Gpu Accelerated Estimation Of A Shared Random Effect Joint Model For Dynamic Prediction, W Jim Zheng, Liang Li

Faculty, Staff and Student Publications

In longitudinal cohort studies, it is often of interest to predict the risk of a terminal clinical event using longitudinal predictor data among subjects at risk by the time of the prediction. The at-risk population changes over time; so does the association between predictors and the outcome, as well as the accumulating longitudinal predictor history. The dynamic nature of this prediction problem has received increasing interest in the literature, but computation often poses a challenge. The widely used joint model of longitudinal and survival data often comes with intensive computation and excessive model fitting time, due to numerical optimization and …

Post-Rift Geomorphological Evolution Of A Passive Continental Margin (Paraíba Region, Northeastern Brazil): Insights From River Profile And Drainage Divide Analysis, Fabio Corrêa Alves, Martin Stokes, Sarah J. Boulton, Fátima Rossetti D De, Morisson Valeriano M De

School of Geography, Earth and Environmental Sciences

The post-rift erosional history of elevated passive continental margins (EPCMs) has been considered of low-rate tectonics across many regions worldwide. However, research in the northeastern Brazilian passive continental margin suggests variations in the post-rift tectonic styles, timing and rates. This is especially the case of the Paraíba region, where there are reports of uplift affecting Quaternary strata. However, transient fluvial features potentially developed during this event remain to be investigated. In this study, we document transient responses of a fluvial landscape promoted by variations in Quaternary tectonic uplift in the Paraíba region, where outcrops are scarce. The aim was to …

Punching Shear Capacity Of Recycled Aggregate Concrete Slabs, Satjapan Leelatanon, Thanongsak Imjai, Monthian Setkit, Reyes Garcia, Boksun Kim

School of Engineering, Computing and Mathematics

This article investigates the punching shear behavior of recycled aggregate concrete (RAC) two-way slabs. Ten 1500 mm × 1500 mm × 100 mm slabs were tested monotonically. Eight slabs were cast with RAC, whereas two control slabs were cast with natural aggregate concrete (NAC). The RAC incorporated coarse recycled concrete aggregate (RCA) at replacement levels of 25%, 50%, 75% and 100%. Two flexural reinforcement ratios (0.8% and 1.5%) were examined. The results show that the normalized punching shear strength of 100% RAC slabs decreased by 6.5% and 9% compared to NAC slabs for ρ = 1.5% and ρ = 0.8%, …

Constraining A Model Of Punctuated River Incision For Quaternary Strath Terrace Formation, Jesse R. Zondervan, Martin Stokes, Matt W. Telfer, Sarah J. Boulton, Anne E. Mather, Jan Pieter Buylaert, Mayank Jain, Andrew S. Murray, Mhamed A. Belfoul

School of Geography, Earth and Environmental Sciences

In the small fraction of Earth's surface with the highest erosion rates such as the Alps and Himalayas quantifying rates of incision, rock uplift and inferring climatic controls on the landscape can be relatively straightforward once the ages of river terraces cut in bedrock (strath terraces) are constrained. However, in many mid to lower relief settings that are more typical of mountain belts worldwide, periods of net river incision and riverbed lowering are relatively short (punctuated), interrupted by long periods of sediment aggradation or stasis. We define a conceptual model of punctuated river incision and strath terrace formation for the …

Progress And Challenges In The Harmonisation Of European Undergraduate Dental Education: A Systematic Literature Review With Narrative Synthesis., Marie Bryce, Daniel Zahra, Lorna Burns, Sally Hanks, Thomas Gale

Peninsula Medical School

Introduction Harmonising education to support workforce mobility has been a policy objective for the European Union. However, alignment across varied national contexts presents challenges in dental education. Methods A systematic literature review with narrative synthesis. Searches of the electronic databases Embase [Ovid]; MEDLINE [Ovid]; Scopus; CINAHL; AMED and PsycINFO were conducted for relevant material published between 2000 and 2019 on undergraduate curricula, quality standards and learning outcomes in dentistry. Results Seventy-six papers met the inclusion criteria. Fifty-three papers were commentaries or editorials, twenty-one were research studies, and two were literature reviews on specific dental subfields. Eighteen of the research studies …

Imbalanced Il-37/Tnf-Α/Ctss Signaling Disrupts Corneal Epithelial Barrier In A Dry Eye Model In Vitro, Zhao Liu, Xin Chen, Cintia S De Paiva, Stephen C Pflugfelder, De-Quan Li

Faculty, Staff and Students Publications

PURPOSE: To explore novel role and molecular mechanism of a natural anti-inflammatory cytokine interleukin (IL) 37 in preventing corneal epithelial barrier disruption from hyperosmolar stress as can occur in dry eye disease.

METHODS: Primary human corneal epithelial cells (HCECs) were cultured from fresh donor limbal explants. An in vitro dry eye model with hyperosmolar stress was established by switching HCECs from isosmolar (312mOsM) to hyperosmolar medium (350-500 mOsM), and some cells were treated with rhIL-37 or rhTNF-α, for different periods (2-48 h). The expression of cytokines and cathepsin S, and barrier protein integrity were evaluated by RT-qPCR, ELISA, and immunofluorescent …

[Nomenclature For Kidney Function And Kidney Diseases - Improving Assessment And Prognosis Through Precision And Comprehensibility], Jürgen Floege, Jan C Galle, Isabelle Jordans, Andreas Kribben, Rainer Oberbauer, Hermann Pavenstädt, Alexander Rosenkranz, Marcus Säemann, Wolfgang C Winkelmayer

Faculty, Staff and Students Publications

Kidney disease represents an increasing global health problem. Its mitigation requires effective communication between all stakeholders involved in assessment, diagnosis and therapy and individuals affected by kidney disease. However, as of today the nomenclature for kidney function and kidney disease is far from uniform. In 2019, the international non-profit organization Kidney Disease: Improving Global Outcomes (KDIGO) has implemented a consensus process to develop a glossary in English language to standardize the nomenclature for kidney function, kidney structure and kidney disease. Guiding principles for this process were (1) precision, (2) patient-centeredness and (3) consistency with KDIGO guidelines. The current position paper …

Azithromycin Use Increases The Risk Of Sudden Cardiac Death In Patients With Hemodialysis-Dependent Kidney Failure, Sana M Al-Khatib, M Alan Brookhart, David J Weber, Wolfgang C Winkelmayer, Jennifer E Flythe

Faculty, Staff and Students Publications

Azithromycin is an antibiotic with QT-prolonging potential commonly prescribed to individuals receiving hemodialysis. Hemodialysis patients have a high prevalence of clinical conditions, such as structural heart disease, that can enhance the pro-arrhythmic effects azithromycin, but were excluded from prior investigations evaluating the cardiac safety of azithromycin. Using data from the United States Renal Data System (2007–2017), we conducted two cohort studies to examine the cardiac safety of azithromycin relative to amoxicillin-based antibiotics (amoxicillin, amoxicillin/clavulanic acid) and levofloxacin (a fluoroquinolone antibiotic known to prolong the QT-interval) in the hemodialysis population. The primary outcome was five-day sudden cardiac death. Using inverse probability …

Heart Failure-Type Symptom Scores In Chronic Kidney Disease: The Importance Of Body Mass Index, Nisha Bansal, Vijay Nambi, Harold I Feldman, Michael G Shlipak, Sankar D Navaneethan

Faculty, Staff and Students Publications

Objectives: This analysis sought to determine factors (including adiposity-related factors) most associated with HF-type symptoms (fatigue, shortness of breath, and edema) in adults with chronic kidney disease (CKD).

Background: Symptom burden impairs quality of life in CKD, especially symptoms that overlap with HF. These symptoms are common regardless of clinical HF diagnosis, and may be affected by subtle cardiac dysfunction, kidney dysfunction, and other factors. We used machine learning to investigate cross-sectional relationships of clinical variables with symptom scores in a CKD cohort.

Methods: Participants in the Chronic Renal Insufficiency Cohort (CRIC) with a baseline modified Kansas City Cardiomyopathy Questionnaire …

Clinical Relevance Of Proteomic Profiling In De Novo Pediatric Acute Myeloid Leukemia: A Children's Oncology Group Study, Fieke W. Hoff, Anneke D. Van Dijk, Yihua Qiu, Chenyue W. Hu, Rhonda E. Ries, Andrew Ligeralde, Gaye N. Jenkins, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Amina A. Qutub, Eveline S J M De Bont, Terzah M. Horton, Steven M. Kornblau

Manuscripts, Articles, Book Chapters and Other Papers

Pediatric acute myeloid leukemia (AML) remains a fatal disease for at least 30% of patients, stressing the need for improved therapies and better risk stratification. As proteins are the unifying feature of (epi)genetic and environmental alterations, and are often targeted by novel chemotherapeutic agents, we studied the proteomic landscape of pediatric AML. Protein expression and activation levels were measured in 500 bulk leukemic patients' samples and 30 control CD34+ cell samples, using reverse phase protein arrays with 296 strictly validated antibodies. The multistep MetaGalaxy analysis methodology was applied and identified nine protein expression signatures (PrSIG), based on strong recurrent protein …

A Longitudinal Study Of Cytochrome P450 2d6 (Cyp2d6) Activity During Adolescence., J Steven Leeder, Andrea Gaedigk, Krista J. Wright, Vincent S. Staggs, Sarah E. Soden, Yvonne S. Lin, Robin E. Pearce

Manuscripts, Articles, Book Chapters and Other Papers

CYP2D6 substrates are among the most highly prescribed medications in teenagers and also commonly associated with serious adverse events. To investigate the relative contributions of genetic variation, growth, and development on CYP2D6 activity during puberty, healthy children and adolescents 7-15 years of age at enrollment participated in a longitudinal phenotyping study involving administration of 0.3 mg/kg dextromethorphan (DM) and 4-h urine collection every 6 months for 3 years (7 total visits). At each visit, height, weight, and sexual maturity were recorded, and CYP2D6 activity was determined as the urinary molar ratio of DM to its metabolite dextrorphan (DX). A total …

Genome Interpretation Using In Silico Predictors Of Variant Impact, Olivier Lichtarge

Faculty, Staff and Students Publications

Estimating the effects of variants found in disease driver genes opens the door to personalized therapeutic opportunities. Clinical associations and laboratory experiments can only characterize a tiny fraction of all the available variants, leaving the majority as variants of unknown significance (VUS). In silico methods bridge this gap by providing instant estimates on a large scale, most often based on the numerous genetic differences between species. Despite concerns that these methods may lack reliability in individual subjects, their numerous practical applications over cohorts suggest they are already helpful and have a role to play in genome interpretation when used at …

Socioeconomic And Comorbid Factors Affecting Mortality And Length Of Stay In Covid-19 Patients, Brendon Cornett, William F Peacock, Anita Datta, Shane P Jenks

Faculty, Staff and Students Publications

Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic exposed and exacerbated health disparities between socioeconomic groups. Our purpose was to determine if age, sex, race, insurance, and comorbidities predicted patients' length of stay (LOS) in the hospital and in-hospital mortality in patients diagnosed with coronavirus disease 2019 (COVID-19) during the early pandemic. Methods Utilizing retrospective, secondarily sourced electronic health record (EHR) data for patients who tested positive for COVID-19 from HCA Healthcare facilities, predictors of LOS and in-hospital mortality were assessed using regression. LOS and in-hospital mortality were assessed using logistic regression and negative binomial regression, respectively. All …

Prevalence And Predictors Of Urine Culture Contamination In Primary Care: A Cross-Sectional Study, Matthew Schlueter, Jennifer L Matas, Samuel E Willis, Lisa C K Danek, Kenneth L Muldrew, Mohammad Zare, Forrest Hudson, Robert L Atmar, Andrew Chou, Barbara W Trautner, Larissa Grigoryan

Faculty, Staff and Students Publications

BACKGROUND: Antimicrobial resistance is a global health threat. To slow resistance and preserve antibiotics, stewardship interventions are increasingly promoted and mandated. Urine cultures are the most common microbiological test in the outpatient setting. Contamination most likely occurs during urine collection from surrounding vaginal, perineal, and epidermal flora. Sample contamination can lead to incorrect diagnosis, unnecessary or inappropriate treatment, poor patient outcomes, and higher costs. Therefore, ensuring proper collection of urinary samples serves as a prime diagnostic stewardship target, one that international nursing societies increasingly endorse as an opportunity for nurse involvement.

OBJECTIVES: Determine the prevalence, predictors, and antibiotic prescribing associated …

Evidence Of Phone Vs Video-Conferencing For Mental Health Treatments: A Review Of The Literature, Anthony Ecker, Giselle Day, Julianna Hogan, Jan Lindsay

Faculty, Staff and Students Publications

PURPOSE OF REVIEW: The goal of this paper is to provide a comparative review of using phone (audio-only) or video for mental health treatments. Our review includes evidence of phone and video's effectiveness in terms of reduced symptomology, retention, satisfaction, therapeutic alliance, and other outcomes of interest. This review also discusses how patients and providers' experiences and attitudes differ between these two modalities. Finally, we present information on different usage rates of phone and video across patient populations and mental health provider types, and different implementation strategies.

RECENT FINDINGS: Treatments through phone and video are both able to reduce symptoms …

Loma Linda Nurse - Vol. 30, Loma Linda University School Of Nursing

Loma Linda Nurse

FEATURES

4 | Elizabeth Bossert— Reflecting on a Journey

8 | Gloria Huerta— A Vision for Leadership

10 | Dawn Graves—First Flight

12 | The Path to Excellence

16 | Nursing Anesthesia Around the Globe

LLUSN HIGHLIGHTS

20-25 | ALUMNI NEWS

26-29 | HOMECOMING

30-33 | ACADEMICS

34-35 | FACULTY UPDATES

Children’S Identity Work In Daily Singing-Based Music Classes: A Case Study Of An Australian Boys’ School, Jason Goopy

Research outputs 2022 to 2026

Music can be a powerful activity and resource in a child’s ongoing identity construction. Rather than something that people have, musical identities are understood to be something people enact and continually work on. The correlation between musical identities and developing music skills raises serious questions regarding the possibilities and responsibilities for school music education and music teachers to positively contribute to children’s emerging identities. This study investigates how daily singing-based music classes at an Australian boys’ school shape and support children’s identity work. Research was conducted using one-on-one semistructured interviews incorporating a “draw and tell” artifact elicitation technique with seven …

Longitudinal Changes In Wellbeing Amongst Breastfeeding Women In Australia And New Zealand During The Covid-19 Pandemic, Vanessa S. Sakalidis, Alethea Rea, Sharon L. Perrella, Jacki Mceachran, Grace Collis, Jennifer Miraudo, Stuart A. Prosser, Lisa Y. Gibson, Desiree Silva, Donna T. Geddes

Research outputs 2022 to 2026

The COVID-19 pandemic has impacted new mothers’ wellbeing and breastfeeding experience. Women have experienced changes in birth and postnatal care and restricted access to their support network. It is unclear how these impacts may have changed over time with shifting rates of infection and policies restricting movement and access to services in Australia and New Zealand. This study investigated the longitudinal effect of the COVID-19 pandemic on breastfeeding and maternal wellbeing in Australia and New Zealand. Mothers (n = 246) completed an online survey every 4 weeks for 6 months that examined feeding methods, maternal mental wellbeing, worries, challenges, and …

Translation And Cross-Cultural Validation Of A Precision Health Tool, The Suboptimal Health Status Questionnaire-25, In Korean, Zheng Guo, Ruoyu Meng, Yulu Zheng, Xingang Li, Ziqi Zhou, Leilei Yu, Qian Tang, Ying Zhao, Monique Garcia, Yuxiang Yan, Song Manshu, Lois A. Balmer, Jun Wen, Haifeng Hou, Xuerui Tan, Wei Wang, Suboptimal Health Study Consortium (Shsc), Global Health Epidemiology Research Group (Gherg)

Research outputs 2022 to 2026

Background

Suboptimal health status (SHS) is a reversible stage between health and illness that is characterized by health complaints, low energy, general weakness, and chronic fatigue. The Suboptimal Health Status Questionnaire-25 (SHSQ-25) has been validated in three major populations (African, Asian, and Caucasian) and is internationally recognized as a reliable and robust tool for health estimation in general populations. This study focused on the development of K-SHSQ-25, a Korean version of the SHSQ-25, from its English version.

Methods

The SHSQ-25 was translated from English to Korean according to international guidelines set forth by the World Health Organization (WHO) for health …

Developing An Alcohol And Other Drug Serious Game For Adolescents: Considerations For Improving Student Engagement, Joanna Nicholas, Brennen Mills, Sara Hansen, Stephen J. Bright, Heather Boyd, Luke Brook, Jess Watson, Luke Hopper

Research outputs 2022 to 2026

Objectives: To explore perceptions of alcohol and other drug (AOD) education and digital game design preferences among Australian adolescents with the goal of identifying key factors to promote engagement in an AOD serious game for Australian secondary school students. Methods: Semi-structured focus groups were conducted with 36 adolescents aged between 13 and 18 years. Qualitative data was analysed using thematic analysis. Results: Participants described heightened engagement with AOD education that incorporated relatable and relevant real-life stories and interactive discussions. They also expressed a desire for learning to focus on practical strategies to reduce AOD harm and overcome social pressure to …

A Tailored Occupational Therapist-Led Vocational Intervention For People With Stroke: Protocol For A Pilot Randomized Controlled Trial, Sophie O'Keefe, Kathryn Radford, Amanda Farrin, Jodi Oakman, Serena Alves-Stein, Geoffrey Cloud, Jacinta Douglas, Mandy Stanley, Natasha A. Lannin

Research outputs 2022 to 2026

Background: Resuming work after stroke is a common goal of working-age adults, yet there are few vocational rehabilitation programs designed to address the unique challenges faced following stroke. The Work intervention was developed to address these gaps. Objective: This paper presents a protocol that outlines the steps that will be undertaken to pilot both the intervention and trial processes for the Work trial. Methods: The Work trial is a 2-arm, prospective, randomized, blinded-assessor study with intention-to-treat analysis. A total of 54 adults of working age who have experienced a stroke <4 months prior will be randomized 1:1 to either (1) an experimental group who will receive a 12-week early vocational intervention (Work intervention) plus usual clinical rehabilitation or (2) a control group who will receive only their usual clinical rehabilitation. Results: Outcomes include study and intervention feasibility and intervention benefit. In addition to evaluating the feasibility of delivering vocational intervention early after stroke, benefit will be assessed by measuring rates of vocational participation and quality-of-life improvements at the 3- and 6-month follow-ups. Process evaluation using data collected during the study, as well as postintervention individual interviews with participants and surveys with trial therapists, will complement quantitative data. Conclusions: The results of the trial will provide details on the feasibility of delivering the Work intervention embedded within the clinical rehabilitation context and inform future trial processes. Pilot data will enable a future definitive trial to determine the clinical effectiveness of vocational rehabilitation when delivered in the early subacute phase of stroke recovery.

Application Of A Sustainability Framework To Enhance Australian Food Literacy Programs In Remote Western Australian Communities, Leisha M. Aberle, Julia R. Platts, Marie A. Kioutis, Louise M. Haustead, Stephanie L. Godrich

Research outputs 2022 to 2026

Issue addressed: Food literacy programs aim to build individuals’ knowledge, skills and self-efficacy to adopt healthy food choices conducive to reducing the risk of chronic diseases, such as obesity. Foodbank WA’s (FBWA) Healthy Food for All ® nutrition programs have supported the improvement of food literacy knowledge and skills among vulnerable people living in the Pilbara. Methods: A Sustainability Framework containing ten sustainability factors was overlaid with social ecological model (SEM) levels of influence to form a matrix. The use of this matrix facilitated sustainability strategy appraisal within three food literacy programs delivered in remote WA. Results: Programs included multiple …

Bi-Substituted Ferrite Garnet Type Magneto-Optic Materials Studied At Esri Nano-Fabrication Laboratories, Ecu, Australia, Mohammad Nur-E-Alam, Mikhail Vasiliev, Kamal Alameh

Research outputs 2022 to 2026

Since 2007, at the Electron Science Research Institute (ESRI) nano-fabrication laboratories, Edith Cowan University, Australia, we have devoted research efforts to the synthesis and characterization of bismuth-containing ferrite-garnet-type thin-film magneto-optic (MO) materials of different compositions. We report on the growth and characteristics of radio frequency (RF) magnetron sputtered bismuth-substituted iron-garnet thin films. We study the process parameters associated with the RF magnetron sputter deposition technique and investigate the results of optimizing process parameters. To achieve the best MO properties, we employ a few unique techniques, such as co-sputtered nanocomposite films and all-garnet multilayer structures, as well as the application of …

Clinical Management Of Financial Toxicity - Identifying Opportunities Through Experiential Insights Of Cancer Survivors, Caregivers, And Social Workers, Christopher J. Longo, Louisa G. Gordon, Rebecca L. Nund, Nicolas H. Hart, Laisa Teleni, Carla Thamm, Olivia Hollingdrake, Fiona Crawford-Williams, Bogda Koczwara, Tamara Ownsworth, Stephen Born, Sue Schoonbeek, Leanne Stone, Christie Barrett, Raymond J. Chan

Research outputs 2022 to 2026

Perspectives of cancer survivors, caregivers, and social workers as key stakeholders on the clinical management of financial toxicity (FT) are critical to identify opportunities for better FT management. Semi-structured interviews (cancer survivors, caregivers) and a focus group (social workers) were undertaken using purposive sampling at a quaternary public hospital in Australia. People with any cancer diagnosis attending the hospital were eligible. Data were analysed using inductive-deductive content analysis techniques. Twenty-two stakeholders (n = 10 cancer survivors of mixed-cancer types, n = 5 caregivers, and n = 7 social workers) participated. Key findings included: (i) genuine concern for FT of cancer …

Consecutive Dosing Of Uvb Irradiation Induces Loss Of Abcb5 Expression And Activation Of Emt And Fibrosis Proteins In Limbal Epithelial Cells Similar To Pterygium Epithelium, M. Domdey, M. A. Kluth, C. Maßlo, C. Ganss, Markus H. Frank, N. Y. Frank, M. T. Coroneo, C. Cursiefen, M. Notara

Research outputs 2022 to 2026

Pterygium pathogenesis is often attributed to a population of altered limbal stem cells, which initiate corneal invasion and drive the hyperproliferation and fibrosis associated with the disease. These cells are thought to undergo epithelial to mesenchymal transition (EMT) and to contribute to subepithelial stromal fibrosis. In this study, the presence of the novel limbal stem cell marker ABCB5 in clusters of basal epithelial pterygium cells co-expressing with P63α and P40 is reported. ABCB5-positive pterygium cells also express EMT-associated fibrosis markers including vimentin and α-SMA while their β-catenin expression is reduced. By using a novel in vitro model of two-dose UV-induced …

Development Of Thai Sensory Patterns Assessment Tool For Children Aged 3–12 Years: Caregiver-Version, Revadee Sutthachai, Anuchart Kaunnil, Supaluck Phadsri, Ilada Pomngen, Mandy Stanley, Tiam Srikhamjak

Research outputs 2022 to 2026

Most existing tools for measuring sensory patterns of children have been developed in Western countries. These tools are complex and may not be culturally appropriate for other contexts that require specific knowledge in the clinical perspective. The aim of this study was to develop a simplified tool called the Thai Sensory Patterns Assessment (TSPA) tool for children. It is designed for children ages 3–12 years old to be completed by their caregiver. The process of creating the tool consisted of drafting a questionnaire and interpreting the result. Partial psychometrics were completed during item development, content validity of items was assessed …

Life-Cycle Assessment Of Fibre-Reinforced Polymers Dwellings Compared To Traditional Structures, Afsaneh Valizadeh, Farhad Aslani

Research outputs 2022 to 2026

Fibre-reinforced polymers (FRP) have been presented as materials that possess properties that are comparable to conventional building materials, while also being more sustainable. This study describes the material and its properties and compares the materials using a life-cycle assessment (LCA) modelling approach. The objective of this paper is to perform a cradle-to-grave (from resource extraction to the disposal stage) analysis of pultruded FRP material and compare it to conventional building materials used in a typical dwelling. This analysis was conducted in accordance with LCA standard EN15978. A streamlined LCA was conducted, whereby the major impacts observed included the global warming …

Species Traits And Geomorphic Setting As Drivers Of Global Soil Carbon Stocks In Seagrass Meadows, H. Kennedy, J. F. Pagès, D. Lagomasino, A. Arias-Ortiz, P. Colarusso, J. W. Fourqurean, M. N. Githaiga, J. L. Howard, D. Krause-Jensen, T. Kuwae, Paul S. Lavery, P. I. Macreadie, N. Marbà, Pere Masqué, I. Mazarrasa, T. Miyajima, Oscar Serrano, C. M. Duarte

Research outputs 2022 to 2026

Our knowledge of the factors that can influence the stock of organic carbon (OC) that is stored in the soil of seagrass meadows is evolving, and several causal effects have been used to explain the variation of stocks observed at local to national scales. To gain a global-scale appreciation of the drivers that cause variation in soil OC stocks, we compiled data on published species-specific traits and OC stocks from monospecific and mixed meadows at multiple geomorphological settings. Species identity was recognized as an influential driver of soil OC stocks, despite their large intraspecific variation. The most important seagrass species …