Digital Commons Network^™

Association Of Prior Periodontal Disease With Cancer – Exploring Epidemiologic Evidence Of Periodontal Exudate-Exposed Site Cancer Risk Versus Remote Gastrointestinal Sites, Asma Alzahrani

Theses and Dissertations

Background: Periodontal disease, a chronic bacterial infection of the gums, if untreated, causes chronic inflammation over years and eventual tooth loss. The associations between periodontal disease (measured by missing teeth) and certain sites of cancer have been established, in epidemiological studies, and attributed to systemic inflammatory impacts causing carcinogenic change over decades. Because periodontal exudates are toxic, containing locally bioactive bacteria and toxins, this study hypothesized and studied the potential higher cancer risk of anatomic sites exposed to oral exudates (exudate-exposed site cancers (EEC); head and neck, oral, pharynx, larynx, esophagus, stomach). The study studied the risk of exudate exposed …

Deciphering The Molecular Circuitry That Controls Iron Regulation In Non-Pathogenic Yeast, Debolina Hati

Theses and Dissertations

The trace metal iron is essential for the survival of almost all living organisms. It is a co-factor for many proteins involved in a variety of vital functions such as respiration, nitrogen fixation, and DNA biosynthesis, to name a few. Iron homeostasis in non-pathogenic fungi such as Schizosaccharomyces pombe has been extensively studied over the past few decades to better understand how intracellular iron is regulated under different environmental conditions. Iron regulation in S. pombe is controlled by two Fe-responsive transcriptional repressors known as Php4 and Fep1. Both rely on iron-sulfur (Fe-S) clusters as signals to balance iron acquisition, storage, …

Uncovering The Diverse Roles Of The Human Cst (Ctc1-Stn1-Ten1) Complex In Resolving Genomic Stress, Percy Logan Schuck

Theses and Dissertations

The CST (CTC1-STN1-TEN1) complex is a heterotrimeric single-stranded DNA binding protein known to stimulate polymerase α-primase (Pol α) and promote telomere length regulation, genome-wide DNA replication and double strand break repair. However, much of its cellular function remains unknown. The focus of my dissertation work was to uncover novel roles of CST in DNA stress response pathways. In particular, my work relates to understanding the function of CST in sister chromatid cohesion (SCC) and base excision repair (BER) as well as characterizing CST protein interactions. SCC is established following DNA replication by loading of the cohesion complex, which encircles replicated …

Motivation And Interest In Participation In Stem Beyond The Classroom Experiences: Effects Of Blended Learning Systems On High School Students, Michael Owdij

Theses and Dissertations

Beyond the classroom experiences are useful learning endeavors designed to help students connect classroom learning to the real world (Kilgo et al., 2015). The purpose of this action research was to evaluate the effect of a technology-based blended learning system on student motivation and interest in participation in beyond the classroom experiences. The blended learning system was offered to STEM-focused junior and senior students who attended a New Jersey high school. The focus of the study was centered around the following questions: How does interest in participation in beyond the classroom experiences change after STEM-focused high school students participate in …

The Effects Of Project-Based Game Development On Student Learning And Attitudes: Action Research In An 8Th Grade Introductory Computer Science Course, Theodore G. Jenks

Theses and Dissertations

The purpose of this action research was to implement a digital game development project and describe its effects on the performance and attitudes of eighth-grade students in a required computer science course at South Carolina School District Alpha. The following research questions were explored: (1) How does the game development project impact participants’ ability to analyze and develop algorithms? (2) What is the effect of the game development project on participants’ attitudes toward computer science? and (3) What is the relationship between participants’ attitudes toward computer science and their performance?

There were 28 participants composed of students in a science, …

Hydrodynamic Response Of A Floating Offshore Wind Turbine (1st Fowt Comparative Study Dataset), Edward Ransley, Scott Brown, Emma Edwards, Tom Tosdevin, Kieran Monk, A. Reynolds, Deborah Greaves, Martyn Hann

Faculty of Science and Engineering Datasets

The 1st FOWT Comparative Study was run in conjunction with the ISOPE 2023 conference, in Ottawa, Canada, 19-23 June 2023 as part of the EPSRC funded project entitled ‘Extreme Loading on Floating Offshore Wind Turbines (FOWT) under Complex Environmental Conditions.‘ The study considers the hydrostatic and hydrodynamic response of a 1:70 scale model of the IEA 15MW reference wind turbine (IEA-15-240-RWT) and UMaine VolturnUS-S semi-submersible platform. The test cases consist of static equilibrium load cases, free decay tests (in heave, surge and pitch) and a pair of focused wave cases (one 'operational' and one 'extreme'). This dataset includes the physical …

Identifying And Understanding Factors Which Affect Persistence In Academically At-Risk Minority Prelicensure Nursing Students: An Action Research Study, Christina L.K. Eaton

Theses and Dissertations

Increased representation of minority groups is imperative for professions like nursing and education. With the growing rate of minority racial and ethnic groups within the United States, there should be corresponding changes within these professions, however there is not. This action research study seeks to explore the factors that affect persistence in academically at-risk minority nursing students at a small Midwestern Christian University. The main research question for this study asks, “What factors do at-risk minority nursing students identify as affecting their ability to persist in our nursing program?” The use of Urie Bronfenbrenner’s Social Ecological Model and Critical Theory …

Behavioral And Neurophysiological Measures Of Speech Auditory Feedback Processing Impairment In Left Hemisphere Stroke, Stacey Sangtian

Theses and Dissertations

The purpose of this study was to identify behavioral and neural correlates of impaired speech auditory feedback processing in people with a history of left-hemisphere stroke (LHS). To do this, we used the altered auditory feedback (AAF) paradigm to externally induce speech errors by randomly shifting the pitch frequency of the online auditory feedback up or down at ±100 cents in 38 LHS and 27 neurologically intact control participants under two experimental conditions: 1) active vocalizations of a steady speech vowel sound “ah,” and 2) passive listening to the playback of the same self-produced vocalizations. Randomized control trials were included …

The Binge Viewing Index: Creating And Testing A New Measure, Larry J. Webster Jr.

Theses and Dissertations

Television Binge Viewing is a media consumption behavior that is in its research infancy. To date, researches have used a dichotomous variable to measure binge viewing. That measure is based on operationalizing binge viewing as having watched two to six episodes of the same television program in one sitting. This research project created and applied a continuous measure by creating the Binge Viewing Index (BVI), which is based on the duration (number of episodes) and the frequency (weekly average) of binge viewing sessions. These dimensions are structured similarly to measures for binge drinking. A national survey demonstrated the intensity of …

Vox Populi Or News From Spain, Translated According To The Spanish Copy Which May Serve To Forewarn Both England And The United Provinces How Far To Trust To Spanish Pretenses, Imprinted In The Year 1620, Thomas Scott

English 144 Class Projects

No abstract provided.

Empirical Studies Of Esg Scores With Corporate Credit Spreads (Insights From Popularity-Based Pricing), Eugene Okyere-Yeboah

Doctoral Dissertations (DBA)

This study examines various factors or characteristics (risk and non-risk) that determine a firm’s credit risk premium, as measured by its credit default swap (CDS) spread, with a particular focus on the impact of environment, social, and governance (ESG) scores. The framework employed is a general equilibrium asset pricing model which integrates classical and behavioral finance elements, known as popularity-based asset pricing. It treats all attributes or characteristics of an asset as ”factors” to which investors assign a degree of popularity, which changes over time. Non-risk characteristics are classified as ”tastes” or ”disagreements”, Fama French (2007). Firms’ degree of adherence …

Teaching Presence In Online Discussions: Relationship-Based Learning By Design, Mary Quest

Dissertations

Activity Theory, Community of Inquiry Model, Interaction Analysis Model, Online learning, Social Construction of Knowledge, Teaching Presence

The Political Economy Of Capitalism In The Digital Age, Economic Democracy, And The Case For The Digital Commons, Alec Stubbs

Dissertations

Autonomist Marxism, capitalism, digital commons, digital economy, economic democracy, social factory

Structural And Transient Kinetic Analysis On Mechanism-Based Inactivators Of Human Ornithine Aminotransferase, Arseniy Butrin

Dissertations

HCC, Hepatocellular carcinoma, MBI, Mechanism-based inactivator, OAT, Ornithine Aminotransferase

Resisting A Political Ontology Of Threat By Embracing Stories Of Survivance Through Storytelling, Conversation, And Joy: An Intimate Insight Into The Lives Of Undocumented Students, Julia F. Mendes

Dissertations

political ontology, storytelling, survivance, undocumented students

The Role Of Gut Microbiome And Scfa Butyrate In The Development Of Obesity Associated Pre-Hfpef, Jomana Hatahet

Dissertations

No abstract provided.

Understanding Teacher Reported Experiences Of Trauma Professional Development/Training, Mayra Alejandra Gaona

Dissertations

trauma informed education, trauma informed practices, trauma informed schools, trauma professional development

Toward An Eco-Cosmopolitanism: Wendell Berry And Ecowomanism In Conversation, Wade Casey

Dissertations

Agriculture, Alice Walker, bell hooks, Ecology, Theology, Wendell Berry

The Roles Of A Probiotic Exopolysaccharide In Breast Cancer, Mai Rachel Nguyen

Dissertations

breast cancer, exopolysaccharide, probiotic

A Comparison Of Education In Post-Revolutionary Mexico And Post-Independence India, Yver Alonso Melchor-Hernandez

Dissertations

Comparison, Education, History, India, Mexico

A Longitudinal Study Of Pain In Youth And Young Adults With Spina Bifida: Three Studies Based On The Bio-Neuropsychosocial Model, Diana Margaret Ohanian

Dissertations

Family Functioning, Neuropsychology, Pain, Pain Coping, Psychological Adjustment, Spina Bifida

Assessing Nursing Student Engagement In Clinical And Simulation Experiences, Karrie Osborne

Dissertations

clinical education, nursing education, student engagement

Communicating Student Outcomes: A Mixed Methods Study Of Communication Effectiveness, Nicholas Branson

Dissertations

Assessment, Communicating evidence, Education, Evaluation, Higher education, Student outcomes

Distinct Roles For Free Fatty Acid Receptor 3 (Ffar3) In Vagal And Spinal Afferents Regulating Energy Balance And Glucose Homeostasis, Tyler M. Cook

Dissertations

energy balance, glucose homeostasis, gut-brain axis, microbiome, nutrient sensing, satiety

Effectiveness Of A Virtual Learning Environment On Pediatric Students’ Knowledge, Self-Confidence And Satisfaction With Learning Growth And Development Concepts, Laura Marie Robbins-Frank

Dissertations

growth and development, knowledge, pediatric nursing students, satisfaction, self-confidence, virtual learning environments

Elucidating The Mechanisms Underlying How Vmp1 Regulates Inflammatory Responses, Stephanie Zack

Dissertations

autophagy, inflammation, mitochondria, NLRP3 inflammasome, SERCA, VMP1

Elucidating The Mechanisms Of Immune Regulation By Bacillus Subtilis, Jesus Zamora-Pineda

Dissertations

bacillus subtilis, exopolysaccharides, inflammation, probiotics, tlr4

International Student Mobility And Migration: Policy Pervasion And The Student Experience, Max Crumley-Effinger

Dissertations

No abstract provided.

Influences Of Child And Caregiver-Directed Home Visitor Behaviors On Caregiver Engagement And Caregiver-Child Interactions, Mary Kienstra Frese

Dissertations

Home Visiting, Parent Support, Prevention

Predicting Asian American College Women’S Leadership Intention Using Social Cognitive Career Theory, Jeong-Eun Suh

Dissertations

No abstract provided.