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Cisplatin And Gemcitabine Exert Opposite Effects On Immunotherapy With Pd-1 Antibody In K-Ras-Driven Cancer, Christophe Glorieux, Xiaojun Xia, Xin You, Zining Wang, Yi Han, Jing Yang, Gauthier Noppe, Christophe De Meester, Jianhua Ling, Annie Robert, Hui Zhang, Sheng-Ping Li, Huamin Wang, Paul J Chiao, Li Zhang, Xiaobing Li, Peng Huang Sep 2022

Cisplatin And Gemcitabine Exert Opposite Effects On Immunotherapy With Pd-1 Antibody In K-Ras-Driven Cancer, Christophe Glorieux, Xiaojun Xia, Xin You, Zining Wang, Yi Han, Jing Yang, Gauthier Noppe, Christophe De Meester, Jianhua Ling, Annie Robert, Hui Zhang, Sheng-Ping Li, Huamin Wang, Paul J Chiao, Li Zhang, Xiaobing Li, Peng Huang

Faculty, Staff and Student Publications

INTRODUCTION: Immunochemotherapy using PD-1/PD-L1 antibodies in combination with chemotherapeutic agents has become a mainstream treatment for cancer patients, but it remains unclear which drug combinations would produce best therapeutic outcome.

OBJECTIVES: The purpose of this study was to investigate two common chemotherapeutic drugs, gemcitabine and cisplatin, for their impacts on the therapeutic efficacy of PD-1 antibody in K-ras-driven cancers known to overexpress PD-L1.

METHODS: Both in vitro assays and syngeneic mouse tumor models were used in this study. Biochemical and molecular assays were used to determine the effects of drugs on T cell functions in cell culture models and in …


September 2022 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate Sep 2022

September 2022 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.


How Should The Statute Of Frauds Apply To Reliance-Based Contracts?, Gregory Scott Crespi Sep 2022

How Should The Statute Of Frauds Apply To Reliance-Based Contracts?, Gregory Scott Crespi

SMU Law Review Forum

The “sufficient writing” requirements of the Statute of Frauds were formulated with bargain-based contracts in mind. It is often difficult if not impossible for persons to meet those requirements for reliance-based contracts, since this would require them to produce a writing signed by the promisor that not only sufficiently evidenced the promise, but also provided sufficient evidence of the other elements of such reliance-based contracts: the foreseeability of their subsequent reliance upon the promise, the fact of their reliance, and that failure to enforce the promise would be unjust.

There are several ways that courts can avoid the harsh results …


Bronchial Artery Revascularization In Lung Transplantation: A Systematic Review And Meta-Analysis., Danial Ahmad, Thomas J O'Malley, Andrew M Jordan, Elizabeth J Maynes, Abhiraj Saxena, Kyle W Prochno, Taufiek K Rajab, Howard T Massey, Richard C Daly, Vakhtang Tchantchaleishvili Sep 2022

Bronchial Artery Revascularization In Lung Transplantation: A Systematic Review And Meta-Analysis., Danial Ahmad, Thomas J O'Malley, Andrew M Jordan, Elizabeth J Maynes, Abhiraj Saxena, Kyle W Prochno, Taufiek K Rajab, Howard T Massey, Richard C Daly, Vakhtang Tchantchaleishvili

Department of Surgery Faculty Papers

Background: Bronchial artery revascularization (BAR) during lung transplantation has been hypothesized to improve early tracheal healing and delay the onset of bronchiolitis obliterans syndrome (BOS). We aimed to assess the outcomes of BAR after lung transplantation.

Methods: Electronic search in Ovid Medline, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Scopus, and Cochrane Controlled Trials Register (CCTR) databases was performed to identify all relevant studies published about lung transplantation with BAR. Studies discussing lung transplantation utilizing BAR were included while those without outcome data such as BOS and survival were excluded. Cohort-level data were extracted and pooled for analysis. …


A Narrative Inquiry On The Entrepreneurial Experiences Of Female Military Spouses With Advanced Degrees, Rosette Mupas-Obedoza Sep 2022

A Narrative Inquiry On The Entrepreneurial Experiences Of Female Military Spouses With Advanced Degrees, Rosette Mupas-Obedoza

All Theses And Dissertations

The purpose of this study was to explore the entrepreneurial experiences of female military spouses with advanced degrees. This study documented how these entrepreneurial experiences may have helped the military spouse population overcome underemployment while their servicemember spouse was still on active duty. Through purposeful sampling, five female military spouse entrepreneurs with advanced degrees were selected to participate in the study. Virtual interviews were conducted to provide a detailed account of their entrepreneurial experiences including how and why they got started in entrepreneurship, challenges and opportunities in entrepreneurship, funding programs and educational services supporting every stage of their entrepreneurship, and …


Black-Capped Chickadee X Carolina Chickadee Hybridization In The Hopewell Sourlands, Central New Jersey, Hannah Bonsey Suthers, C. Sharyn Magee Sep 2022

Black-Capped Chickadee X Carolina Chickadee Hybridization In The Hopewell Sourlands, Central New Jersey, Hannah Bonsey Suthers, C. Sharyn Magee

North American Bird Bander

No abstract provided.


Daily And Annual Weight Changes In Inca Doves, Allan J. Mueller Sep 2022

Daily And Annual Weight Changes In Inca Doves, Allan J. Mueller

North American Bird Bander

No abstract provided.


Site Fidelity In Seven Passerines In Southern California, Walter H. Sakai Sep 2022

Site Fidelity In Seven Passerines In Southern California, Walter H. Sakai

North American Bird Bander

No abstract provided.


Errata For Nabb Volume 47 Numbers 1 & 2, North American Bird Bander Sep 2022

Errata For Nabb Volume 47 Numbers 1 & 2, North American Bird Bander

North American Bird Bander

No abstract provided.


An Upside-Down Primary In A Sharp-Shinned Hawk, Daniel E. Erickson Sep 2022

An Upside-Down Primary In A Sharp-Shinned Hawk, Daniel E. Erickson

North American Bird Bander

No abstract provided.


Unexpected Directional Movement Of A Spring Migrant Ruby-Throated Hummingbird, Allen T. Chartier Sep 2022

Unexpected Directional Movement Of A Spring Migrant Ruby-Throated Hummingbird, Allen T. Chartier

North American Bird Bander

No abstract provided.


Two Unusual American Robin Re-Encounters From Michigan, Allen T. Chartier Sep 2022

Two Unusual American Robin Re-Encounters From Michigan, Allen T. Chartier

North American Bird Bander

No abstract provided.


An Old Orange-Crowned Warbler, Rebecca D. Bracken, Scott A. Rush Sep 2022

An Old Orange-Crowned Warbler, Rebecca D. Bracken, Scott A. Rush

North American Bird Bander

No abstract provided.


Nabb Publication Committee Update, Andy Thiede Sep 2022

Nabb Publication Committee Update, Andy Thiede

North American Bird Bander

No abstract provided.


Atlantic Flyway Review Spring 2019 Compiled By Aaron Given, Aaron Given Sep 2022

Atlantic Flyway Review Spring 2019 Compiled By Aaron Given, Aaron Given

North American Bird Bander

No abstract provided.


Atlantic Flyway Review Fall 2019 Compiled By Aaron Given, Aaron Given Sep 2022

Atlantic Flyway Review Fall 2019 Compiled By Aaron Given, Aaron Given

North American Bird Bander

No abstract provided.


Atlantic Flyway Review Spring 2020 Compiled By Aaron Given, Aaron Given Sep 2022

Atlantic Flyway Review Spring 2020 Compiled By Aaron Given, Aaron Given

North American Bird Bander

No abstract provided.


Atlantic Flyway Review Fall 2020 Compiled By Aaron Given, Aaron Given Sep 2022

Atlantic Flyway Review Fall 2020 Compiled By Aaron Given, Aaron Given

North American Bird Bander

No abstract provided.


New Wbba President, North American Bird Bander Sep 2022

New Wbba President, North American Bird Bander

North American Bird Bander

No abstract provided.


Peter Pyle’S New Book, North American Bird Bander Sep 2022

Peter Pyle’S New Book, North American Bird Bander

North American Bird Bander

No abstract provided.


Wbba Helps Host Banding Webinars, Steve Albert Sep 2022

Wbba Helps Host Banding Webinars, Steve Albert

North American Bird Bander

No abstract provided.


Next May At Bear Divide, North American Bird Bander Sep 2022

Next May At Bear Divide, North American Bird Bander

North American Bird Bander

No abstract provided.


Is The Term 'Bird Banding' Obsolete? And What Should We Do About It, Steven Albert, C. John Ralph, Adam Hannuksela Sep 2022

Is The Term 'Bird Banding' Obsolete? And What Should We Do About It, Steven Albert, C. John Ralph, Adam Hannuksela

North American Bird Bander

No abstract provided.


Front Matter, North American Bird Bander Sep 2022

Front Matter, North American Bird Bander

North American Bird Bander

No abstract provided.


Back Matter, North American Bird Bander Sep 2022

Back Matter, North American Bird Bander

North American Bird Bander

No abstract provided.


Occupational Stress In Psychiatric Nurses And The Impact Of Self-Care Activities, Jacqueline Lowe Sep 2022

Occupational Stress In Psychiatric Nurses And The Impact Of Self-Care Activities, Jacqueline Lowe

Doctor of Nursing Practice Projects

Background

The nursing profession is an extremely stressful occupation. Psychiatric nurses face many of the general stressors that are inherent within the profession as well as unique challenges in taking care of psychiatric patients. Prolonged exposure to stress can impact the quality of the nurses' lives as well as the quality of patient care. Engagement in self-care activities can promote the well-being of psychiatric nurses.

Purpose

To investigate the level of occupational stress in psychiatric nurses and offer them a guided six-week program on self-care activities. This intervention was measured for any change in the level of occupational stress that …


Medicaid Expansion Expectations, Deborah Farringer Sep 2022

Medicaid Expansion Expectations, Deborah Farringer

Law Faculty Scholarship

Although financial stability in rural hospitals has been a relatively long-standing national problem, in the last decade, hospital closures and the incidence of highly distressed hospitals in rural areas have disproportionately impacted certain states. States that have not expanded their Medicaid programs under the Affordable Care Act, which implemented a program to extend additional federal support to cover adults living below 138% of the federal poverty line (referred to herein as “Medicaid Expansion”), are bearing the brunt of this crisis. Although the reason for hospital closures is multi-faceted and complex, health policy experts have consistently identified the lack of Medicaid …


Insider Trading Restrictions And Real Activities Earnings Management: International Evidence, Yuanto Kusnadi, Yuanto Kusnadi, Jiwei Wang, Yujie Wang Sep 2022

Insider Trading Restrictions And Real Activities Earnings Management: International Evidence, Yuanto Kusnadi, Yuanto Kusnadi, Jiwei Wang, Yujie Wang

Research Collection School Of Accountancy

We examine the implications of insider trading restrictions on firms’ real activities earnings management in an international setting. Using a sample of 28 countries over the period from 1992 to 2007, we find evidence that is supportive of the substitution hypothesis, in that managers have incentives to substitute accruals earnings management for real activities earnings management. This effect is found to be more pronounced for firms in countries with more restrictive insider trading regulation. Our result is robust to alternative measures of real activities earnings management and insider trading restrictions, alternative sub-samples, alternative regression specifications, and controlling for endogeneity. In …


Contextualizing The Organizational Mindset, Joseph A. Carpini, Burak Oc Sep 2022

Contextualizing The Organizational Mindset, Joseph A. Carpini, Burak Oc

Research Collection Lee Kong Chian School Of Business

Although Schneider and Pulakos (2022, p. 2) call for scholars to adopt an “organizational mindset,” which includes “an increased organizational frame of reference on variables of interest,” the authors have overlooked the importance of contextualizing such a mindset. Contextualizing “entails linking observations to a set of relevant facts, events, or points of view that make possible research and theory that form part of a larger whole” (Rousseau & Fried, 2001, p. 1). Contextualizing is essential because it provides a common vernacular that facilitates the valid and reliable extension of the industrial-organizational (I-O) mindset to the study of organizational differences and …


Employer Image Within And Across Industries: Moving Beyond Assessing Points-Of-Relevance To Identifying Points-Of-Difference, Greet Van Hoye, Filip Lievens, Bert Weijters, Saartje Cromheecke Sep 2022

Employer Image Within And Across Industries: Moving Beyond Assessing Points-Of-Relevance To Identifying Points-Of-Difference, Greet Van Hoye, Filip Lievens, Bert Weijters, Saartje Cromheecke

Research Collection Lee Kong Chian School Of Business

This study draws from brand positioning research to introduce the notions of points-of-relevance and points-of-difference to employer image research. Similar to prior research, this means that we start by investigating the relevant image attributes (points-of-relevance) that potential applicants use for judging organizations' attractiveness as an employer. However, we go beyond past research by examining whether the same points-of-relevance are used within and across industries. Next, we further extend current research by identifying which of the relevant image attributes also serve as points-of-difference for distinguishing between organizations and industries. The sample consisted of 24 organizations from 6 industries (total N = …