Digital Commons Network^™

Integrated Host-Microbe Plasma Metagenomics For Sepsis Diagnosis In A Prospective Cohort Of Critically Ill Adults, Katrina L Kalantar, Pratik Sinha, Et Al.

2020-Current year OA Pubs

We carried out integrated host and pathogen metagenomic RNA and DNA next generation sequencing (mNGS) of whole blood (n = 221) and plasma (n = 138) from critically ill patients following hospital admission. We assigned patients into sepsis groups on the basis of clinical and microbiological criteria. From whole-blood gene expression data, we distinguished patients with sepsis from patients with non-infectious systemic inflammatory conditions using a trained bagged support vector machine (bSVM) classifier (area under the receiver operating characteristic curve (AUC) = 0.81 in the training set; AUC = 0.82 in a held-out validation set). Plasma RNA also yielded a …

Proportioning Collection Space And Learning In An Academic Library: Collection Performance Indicators, Christopher Stewart, Louise Lowe

Faculty Scholarship

Assessment on university campuses increasingly emphasizes learning outcomes and student success. Academic librarians need to identify relationships between their collection spaces and the learning activities of the university in order to play a role in the environment of assessment. Measuring the propor- tions of discipline-oriented content of library collections and comparing those proportions to discipline-oriented learning activities produces collection performance indicators. Academic libraries can use collection performance indicators to assess how well their collection spaces correspond to student demand and student success using readily available metrics. Collection performance indicators answers a gap in library literature per- taining to relationships between …

"Glad She Was There, Otherwise I Would Have Failed": Student Perceptions Of An Embedded Librarian, Susan Franzen, Mallory Jallas, Joshua Newport, Caitlin Stewart, Allison Rand

Faculty and Staff Publications – Milner Library

Embedded librarianship offers students, faculty, and librarians the opportunity to work closely together. After many years of collaborating with faculty partners and assisting students both inside the classroom and out, an embedded librarian in an undergraduate nursing research course sought the student perspective on having an embedded librarian.

In spring 2021, the research team scheduled focus groups to measure students’ perceptions of the embedded librarian’s impact on their research experience. Twenty-four students in five focus groups participated via Zoom. The group members met with students to capture firsthand accounts of their experiences.

This poster presentation will highlight students’ perceptions of …

Monodelphis Domestica Induced Pluripotent Stem Cells Reveal Metatherian Pluripotency Architecture, Satish Kumar, Erica De Leon, Jose C. Granados, Deanne J. Whitworth, Jane F. Vandeberg

School of Medicine Publications

Marsupials have been a powerful comparative model to understand mammalian biology. However, because of the unique characteristics of their embryology, marsupial pluripotency architecture remains to be fully understood, and nobody has succeeded in developing embryonic stem cells (ESCs) from any marsupial species. We have developed an integration-free iPSC reprogramming method and established validated iPSCs from two inbred strains of a marsupial, Monodelphis domestica. The monoiPSCs showed a significant (6181 DE-genes) and highly uniform (r2 [95% CI] = 0.973 ± 0.007) resetting of the cellular transcriptome and were similar to eutherian ESCs and iPSCs in their overall transcriptomic profiles. …

Survey For Caregivers Of People With Autism Spectrum In Chile: Access To Health And Education Services, Satisfaction, Quality Of Life And Stigma [Encuesta Para Cuidadores De Personas Del Espectro Autista En Chile. Acceso A Servicios De Salud Y Educación, Satisfacción, Calidad De Vida Y Estigma], Ricardo Garcia, Matías Irarrázaval, Isabel Lopez, Sofia Riesle, Marci Cabezas Gonzalez, Andrea Moyano, Gabriela Garrido, Daniel Valdez, Cristiane S. De Paula, Cecilia Montiel-Nava

Psychological Science Faculty Publications

People on the Autism Spectrum (AS) face multiple health, education, social, and economic problems. There is limited available information in Chile. \

Objective: To describe the access and satisfaction with health and education services, family and economic impact, stigma, and quality of life of people with AS and their families in Chile.

Subjects and Method: Parents/caregivers of AS persons completed the Caregiver Needs Survey, developed by Autism Speaks, which includes demographic information, characteristics of AS persons (previously published), use of health and education services, parents/caregivers' perceptions of satisfaction, impact, stigma, and quality of life.

Results: 291 caregivers (86% mothers) of …

Human Journeys In The Digital Age: Advances And Challenges In Digital Historical Migration Studies, Paul Longley Arthur, Isabel Smith

Research outputs 2022 to 2026

Accelerations in migration, mobility, and processes of globalization in recent decades have intersected with parallel developments in information and communications technology (ICT). These advances have had profound influences on historical and cultural research. With reference to a diverse range of international projects, this paper outlines major directions and opportunities in the growing field of Digital Historical Migration Studies (DHMS). The “digital turn” brings opportunities for integrating data on macro and micro scales, and finding new ways to combine and explore tensions between quantitative and qualitative materials, and between external observations of migrants and migration and self-representations by migrants. The plural …

Summing Feynman Diagrams In The Worldline Formalism, C Schubert, N Ahmadiniaz, J Edwards, C Lopez-Arcos, Ma Lopez-Lopez, Cm Mata, J Nicasio

School of Engineering, Computing and Mathematics

The worldline formalism shares with string theory the property that it allows one to write down master integrals that effectively combine the contributions of many Feynman diagrams. While at the one-loop level these diagrams differ only by the position of the external legs along a fixed line or loop, at multiloop they generally involve different topologies. Here we summarize various efforts that have been made over the years to exploit this property in a computationally meaningful way. As a first example, we show how to generalize the Landau-Khalatnikov-Fradkin formula for the non-perturbative gauge transformation of the fermion propagator in QED …

Summing Feynman Diagrams In The Worldline Formalism, J Edwards, N Ahmadiniaz, C Lopez-Arcos, Ma Lopez-Lopez, Mata C Moctezuma, J Nicasio, C Schubert

School of Engineering, Computing and Mathematics

The worldline formalism shares with string theory the property that it allows one to write down master integrals that effectively combine the contributions of many Feynman diagrams. While at the one-loop level these diagrams differ only by the position of the external legs along a fixed line or loop, at multiloop they generally involve different topologies. Here we summarize various efforts that have been made over the years to exploit this property in a computationally meaningful way. As a first example, we show how to generalize the Landau-Khalatnikov-Fradkin formula for the non-perturbative gauge transformation of the fermion propagator in QED …

Disturbances In North American Boreal Forest And Arctic Tundra: Impacts, Interactions, And Responses, Adrianna C. Foster, Jonathan A. Wang, Gerald V. Frost, Scott J. Davidson, Elizabeth Hoy, Kevin W. Turner, Oliver Sonnentag, Howard Epstein, Logan T. Berner, Amanda H. Armstrong, Mary Kang, Brendan M. Rogers, Elizabeth Campbell, Kimberley R. Miner, Kathleen M. Orndahl, Laura Bourgeau-Chavez, David A. Lutz, Nancy H. F. French, Dong Chen, Jinyang Du, Tatiana A. Shestakova, Jacquelyn K. Shuman, Ken Tape, Anna Maria Virkkala, Christopher Potter, Scott Goetz

Michigan Tech Publications, Part 1

Ecosystems in the North American Arctic-Boreal Zone (ABZ) experience a diverse set of disturbances associated with wildfire, permafrost dynamics, geomorphic processes, insect outbreaks and pathogens, extreme weather events, and human activity. Climate warming in the ABZ is occurring at over twice the rate of the global average, and as a result the extent, frequency, and severity of these disturbances are increasing rapidly. Disturbances in the ABZ span a wide gradient of spatiotemporal scales and have varying impacts on ecosystem properties and function. However, many ABZ disturbances are relatively understudied and have different sensitivities to climate and trajectories of recovery, resulting …

African Governments’ Foreign Publics Engagement: Public Diplomacy In African Perspective, Isaac Antwiboasiako

Articles

Scholars over the years have delved into the discourse of states’ foreign publics engagement in achieving their foreign policy objectives. This analysis is done generally with the western perspective of public diplomacy with recent Asian scholarship evolving. As a result, this study aims to reflect on public diplomacy from an African perspective. Therefore, it analyses how African governments have engaged their foreign publics (foreign governments and their citizens) to attract foreign aid, tourism, and investments in their nation-building and development trajectory. The article explores African public diplomacy mechanisms such as diasporas, nation branding, cultural diplomacy, and many others. It also …

2022-10-20 Revision Of Academic Appeals Committee (Draft), Morehead State University. Faculty Senate., Acadmic Appeals Committee.

Faculty Senate Records

A draft of a revision of the Academic Appeals Committee submitted to the Faculty Senate on October 22, 2022.

2022-10-20 Faculty Senate Newsletter, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate newsletter from October 20, 2022.

2022-10-20 Faculty Senate Meeting Minutes, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate meeting minutes from October 20, 2022.

Convolutional Long-Short Term Memory Network With Multi-Head Attention Mechanism For Traffic Flow Prediction, Yupeng Wei, Hongrui Liu

Faculty Research, Scholarly, and Creative Activity

Accurate predictive modeling of traffic flow is critically important as it allows transportation users to make wise decisions to circumvent traffic congestion regions. The advanced development of sensing technology makes big data more affordable and accessible, meaning that data-driven methods have been increasingly adopted for traffic flow prediction. Although numerous data-driven methods have been introduced for traffic flow predictions, existing data-driven methods cannot consider the correlation of the extracted high-dimensional features and cannot use the most relevant part of the traffic flow data to make predictions. To address these issues, this work proposes a decoder convolutional LSTM network, where the …

Understanding Sexual And Gender Minority Privacy, Darra Hofman, Michele A. L. Villagran, Souvick Ghosh

Faculty Research, Scholarly, and Creative Activity

This panel presentation is a summary update of the recent research from the 2021 ALISE Research Grant Competition Award: Educating for Equity?: Sexual and Gender Minority Privacy in Library and Information Studies Education. This session aligns with the conference theme, “Go back and Get It: From One Narrative to Many” by illustrating the ways in which “privacy” is a polysemous concept, and information professionals grappling with privacy from a policy perspective must be prepared for its multi-faceted nature and the distinct privacy needs of different communities.
New library and information professionals are expected to uphold a number of ethical principles, …

Teaching And Learning The Ninth Principle Of The Ala Code Of Ethics, John Budd, Suliman Hawamdeh, Bharat Mehra, Michele A. L. Villagran

Faculty Research, Scholarly, and Creative Activity

In 2021 the American Library Association (ALA) Council approved a ninth principle to be added to the ALA Code of Ethics. The principle reads, “We affirm the inherent dignity and rights of every person. We work to recognize and dismantle systemic and individual biases; to confront inequity and oppression; to enhance diversity and inclusion; and to advance racial and social justice in our libraries, communities, profession, and associations through awareness, advocacy, education, collaboration, services, and allocation of resources and spaces.” This principle is in keeping with the Association for Library and Information Science Education (ALISE) Ethical Guidelines for Library and …

Transforming Thesaurus Records Into Marc 21 And Mads: Designing A Framework For Libraries, Sukumar Mandal, Sailendra Malik

Library Philosophy and Practice (e-journal)

Purpose

This paper analyzes various thesaurus formats for converting data and how they can easily be implemented in libraries. These data formats are very important and necessary because they can easily transfer data from one system to another. The main focus of this system is on the data format of the Thesaurus Constructon.

Methodology

It is made with the TemaTres tool, which is used by many other tools. It has many new and modern features that librarians can use to create a new interface. In other words, it is possible to link other software very easily through these formats. There …

Neoplastic Cell Enrichment Of Tumor Tissues Using Coring And Laser Microdissection For Proteomic And Genomic Analyses Of Pancreatic Ductal Adenocarcinoma, Qing Kay Li, Daniel Cui Zhou, Yize Li, Rita Jui-Hsien Lu, Li Ding, Et Al.

2020-Current year OA Pubs

BACKGROUND: The identification of differentially expressed tumor-associated proteins and genomic alterations driving neoplasia is critical in the development of clinical assays to detect cancers and forms the foundation for understanding cancer biology. One of the challenges in the analysis of pancreatic ductal adenocarcinoma (PDAC) is the low neoplastic cellularity and heterogeneous composition of bulk tumors. To enrich neoplastic cells from bulk tumor tissue, coring, and laser microdissection (LMD) sampling techniques have been employed. In this study, we assessed the protein and KRAS mutation changes associated with samples obtained by these enrichment techniques and evaluated the fraction of neoplastic cells in …

A Comparison Of Bioimpedance Analysis Vs. Dual X-Ray Absorptiometry For Body Composition Assessment In Postpartum Women And Non-Postpartum Controls, Valene Garr Barry, Samantha L Martin, Paula Chandler-Laney, Ebony B Carter, Camille S Worthington

2020-Current year OA Pubs

Postpartum fat mass (FM) and fat-free mass (FFM) may be informative predictors of future disease risk among women; hence, there is growing use of bioelectrical impedance analysis (BIA) to quantify FFM and FM among postpartum women due to the quick, non-invasive, and inexpensive nature of BIA. Despite this, very few studies have examined BIA's performance, and it remains unclear as to whether specific BIA equations are needed for postpartum women. To explore these questions, we measured total body FFM and FM with a multi-frequency, segmental BIA, and dual-X-ray absorptiometry (DXA) in (1) women at one and four months postpartum (

Enriched Dietary Saturated Fatty Acids Induce Trained Immunity Via Ceramide Production That Enhances Severity Of Endotoxemia And Clearance Of Infection, Amy L. Seufert, James W. Hickman, Ste K. Traxler, Rachael M. Peterson, Trent A. Waugh, Sydney L. Lashley, Natalia Shulzhenko, Ruth J. Napier, Brooke A. Napier

Biology Faculty Publications and Presentations

Trained immunity is an innate immune memory response that is induced by a primary inflammatory stimulus that sensitizes monocytes and macrophages to a secondary pathogenic challenge, reprogramming the host response to infection and inflammatory disease. Dietary fatty acids can act as inflammatory stimuli, but it is unknown if they can act as the primary stimuli to induce trained immunity. Here we find mice fed a diet enriched exclusively in saturated fatty acids (ketogenic diet; KD) confer a hyper-inflammatory response to systemic lipopolysaccharide (LPS) and increased mortality, independent of diet-induced microbiome and hyperglycemia. We find KD alters the composition of the …

Time Management Experiences Among Adult Learners In An Online Undergraduate Degree Program, Russell Lee Fox

Doctoral Dissertations and Projects

The purpose of this case study was to discover the time management experiences of adult learners in an online undergraduate degree program at a mid-sized, Midwestern private university. The theory guiding this study was Tourangbam’s (2011) time equity theory as it emphasized the connection between time management and both productivity and life satisfaction. Data was collected through online (Zoom) interviews, a virtual (Zoom) focus group, and photovoice (Wang & Burris, 1992) exercise in which participants took photographs that represented their priorities, obligations, and time-wasters, which were the three categories of time management identified in time equity theory (Tourangbam, 2011). Data …

A Phenomenological Study Design Of Receiving Student Feedback: Professor Shared Experiences, James Sigler

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the experience of using student feedback for professors at higher-education accredited institutions in the United States of America. The essential question of this research was what are the lived experiences of professors when receiving feedback from students? This research found that professors use student feedback if the feedback is found to be valid. The essence of the phenomena was found using the guiding theory of feedback intervention created by Kluger and DeNisi. The 10 professors of this study represented a combined teaching tenure of over 200 years of experience who …

The Lived Experience Of Personnel Adversely Impacted By Toxic Leadership: A Phenomenological Study, Jeremy B. Piasecki

Doctoral Dissertations and Projects

The purpose of this qualitative phenomenological study was to understand the lived experience of personnel adversely impacted by toxic leadership. This topic is important to study because the harassment, bullying, and narcissistic behavior exhibited by toxic leaders and negative environments have severe adverse implications for personnel, such as reduced accomplishments, mental health, lack of trust, and overall wellbeing. In order to further understand the phenomenon, the following research questions guided the study: (a) What is the lived experience of personnel adversely impacted by toxic leadership? (b) How were the personnel impacted by the change in the culture and environment? (c) …

Restoration Jewish Evangelism: A Dispensational Paradigm For Jewish Evangelism, Justin R. Woods

Doctoral Dissertations and Projects

Local Jewish populations within proximity of U.S. churches are perishing in their need to hear the Christian gospel. Obstacles to Jewish evangelism have festered through the centuries. Modern scholarship has held culpable the supersessionist traditions from the early church fathers and carried over to the present day. Dispensational pastors and scholars have acted on the front lines to correct this grievance. Restoration Jewish Evangelism (RJE) supplies a template of Jewish evangelism centered on a dispensational view of Romans 9—11. The goal of this project includes strengthening the parishioners’ situational awareness and self-confidence to engage in sharing the gospel of the …

Self-Compassion Education, A Framework For A Self-Care Plan For Military Chaplains: A Qualitative Study, Opeyemi Samuel Oluwafisoye

Doctoral Dissertations and Projects

Self-compassion education promotes coping skills to ease emotional discomfort and suffering by offering a sense of belonging, understanding, and caring, similar to the benefits of empathy for someone else. No research has been done examining the buffering importance of self-compassion education as a framework for self-care among military chaplains. The current study was tailored toward understanding military chaplains’ perception of self-compassion as a framework for self-care. The dissertation aimed to determine a need to formulate a self-care plan for military chaplains to reduce their pain after helping Soldiers and their families diagnosed with trauma through different interventions. The goal of …

Grant Us Wisdom, Grant Us Courage For The Facing Of Change Leadership: A Case Study Of The Change Leadership Of J. Gresham Machen, Peter Raymond Sniffin

Doctoral Dissertations and Projects

Ministry leaders are ill-prepared to execute the inevitable requirement of change leadership. As a result of this leadership shortcoming, necessary change efforts are either avoided or fail. During the Fundamentalist and Modernist Controversy of the early 20th Century, J. Gresham Machen provided change leadership in response to doctrinal error in the church that transformed his ministry context and Presbyterianism in the United States as it was then structured. In Paul’s Epistle to the Galatians, Paul also exercised leadership to drive change away from doctrinal error in the church. A case study examining Machen’s change leadership in light of Paul’s example …

Objective Assessment Of Upper-Extremity Motor Functions In Spinocerebellar Ataxia Using Wearable Sensors, Reza Mohammadi-Ghazi, Hung Nguyen, Ram Kinker Mishra, Ana Enriquez, Bijan Najafi, Christopher D Stephen, Anoopum S Gupta, Jeremy D Schmahmann, Ashkan Vaziri

Center on Aging Staff Publications

The study presents a novel approach to objectively assessing the upper-extremity motor symptoms in spinocerebellar ataxia (SCA) using data collected via a wearable sensor worn on the patient’s wrist during upper-extremity tasks associated with the Assessment and Rating of Ataxia (SARA). First, we developed an algorithm for detecting/extracting the cycles of the finger-to-nose test (FNT). We extracted multiple features from the detected cycles and identified features and parameters correlated with the SARA scores. Additionally, we developed models to predict the severity of symptoms based on the FNT. The proposed technique was validated on a dataset comprising the seventeen (n …

Control Of Ribosomal Rna Synthesis By Hematopoietic Transcription Factors, Charles Antony, Subin S George, Justin Blum, Patrick Somers, Chelsea L Thorsheim, Dexter J Wu-Corts, Yuxi Ai, Long Gao, Kaosheng Lv, Michel G Tremblay, Tom Moss, Kai Tan, Jeremy E Wilusz, Austen R D Ganley, Maxim Pimkin, Vikram R Paralkar

Faculty, Staff and Students Publications

Ribosomal RNAs (rRNAs) are the most abundant cellular RNAs, and their synthesis from rDNA repeats by RNA polymerase I accounts for the bulk of all transcription. Despite substantial variation in rRNA transcription rates across cell types, little is known about cell-type-specific factors that bind rDNA and regulate rRNA transcription to meet tissue-specific needs. Using hematopoiesis as a model system, we mapped about 2,200 ChIP-seq datasets for 250 transcription factors (TFs) and chromatin proteins to human and mouse rDNA and identified robust binding of multiple TF families to canonical TF motifs on rDNA. Using a 47S-FISH-Flow assay developed for nascent rRNA …

Effect Of Fine Aggregate And Pva Fiber Content On The Properties Of Metakaolin-Based Engineered Geopolymer Composites, Ruwa Abufarsakh

LSU Master's Theses

The mechanical and physical properties of novel metakaolin (MK) based Engineered Geopolymer Composites (EGCs) consisting of locally available river sand (RS) or manufactured microsilica sand (MS) reinforced with polyvinyl alcohol (PVA) fiber were studied. Plain geopolymer (GP) binder, GP mortars, and fiber-reinforced composites were also studied. Aspects of the material composition that were investigated in this study include binder composition, aggregate type, and PVA fiber content. Per the compressive strength results, GP mortars presented greater compressive strength than GP binder where the GP mortars manufactured with lower water to solids ratio exhibited greater compressive strengths. Furthermore, the incorporation of PVA …

Webinar: Community Transportation Academies: Rethinking Effective Community Engagement Around Transportation Decision-Making, Nathan Mcneil, Keith Bartholomew, Andrea Olson, Laura Hanson, Thuy Tu

TREC Webinar Series

This webinar will introduce you to the concept of the Community Transportation Academy (CTA), a model which has been operating in Portland for over 30 years in the form of the Portland Traffic and Transportation (PTT) class. Now catching on in other cities, the project team recently implemented the Wasatch Transportation Academy (WTA) in Salt Lake City. The presenters also include key stakeholders (and guest lecturers) in the WTA, and the PTT instructor. The presentation will include discussions about why CTAs can be good for both community members and transportation agencies/practitioners, and how you can bring a CTA to your …