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2022-11-02 Seattle University Hosts Tense Congressional Debate, Naja Johnson Nov 2022

2022-11-02 Seattle University Hosts Tense Congressional Debate, Naja Johnson

The Spectator Online

No abstract provided.


2022-11-02 Time Out Session: Akili Kasim Closes Out Record-Breaking Career, Tyra Okuda Nov 2022

2022-11-02 Time Out Session: Akili Kasim Closes Out Record-Breaking Career, Tyra Okuda

The Spectator Online

No abstract provided.


2022-11-02 Kedai Makan Co-Owner Reflects On Closing After 10 Years, Emma Ferguson Nov 2022

2022-11-02 Kedai Makan Co-Owner Reflects On Closing After 10 Years, Emma Ferguson

The Spectator Online

No abstract provided.


2022-11-02 The History Of Hiphop At The Mopop, Sean Campbell Nov 2022

2022-11-02 The History Of Hiphop At The Mopop, Sean Campbell

The Spectator Online

No abstract provided.


2022-11-02 Student Finances And Food Justice: Redhawks Navigate A Patchwork Of Resources, Leila Bunker Nov 2022

2022-11-02 Student Finances And Food Justice: Redhawks Navigate A Patchwork Of Resources, Leila Bunker

The Spectator Online

No abstract provided.


2022-11-02 Weeks In Review: October 17-30 (Sports), Camryn Mata Nov 2022

2022-11-02 Weeks In Review: October 17-30 (Sports), Camryn Mata

The Spectator Online

No abstract provided.


Secreted Fas Decoys Enhance The Antitumor Activity Of Engineered And Bystander T Cells In Fas Ligand-Expressing Solid Tumors, Pradip Bajgain, Alejandro G Torres Chavez, Kishore Balasubramanian, Lindsey Fleckenstein, Premal Lulla, Helen E Heslop, Juan Vera, Ann M Leen Nov 2022

Secreted Fas Decoys Enhance The Antitumor Activity Of Engineered And Bystander T Cells In Fas Ligand-Expressing Solid Tumors, Pradip Bajgain, Alejandro G Torres Chavez, Kishore Balasubramanian, Lindsey Fleckenstein, Premal Lulla, Helen E Heslop, Juan Vera, Ann M Leen

Faculty, Staff and Students Publications

T-cell immunotherapy has demonstrated remarkable clinical outcomes in certain hematologic malignancies. However, efficacy in solid tumors has been suboptimal, partially due to the hostile tumor microenvironment composed of immune-inhibitory molecules. One such suppressive agent abundantly expressed in solid tumors is Fas ligand (FasL), which can trigger apoptosis of Fas-expressing effector cells such as T cells and natural killer (NK) cells. To alleviate this FasL-induced suppression of tumor-specific immune cells in solid tumors, we describe here the development of a Fas decoy that is secreted by engineered cells upon activation and sequesters the ligand, preventing it from engaging with Fas on …


Annular Bullous Lesions In A Child From Uganda: Chronic Bullous Disease Of Childhood, Austin Ambur, Timothy A. Nyckowski, Aashni Bhukhan Nov 2022

Annular Bullous Lesions In A Child From Uganda: Chronic Bullous Disease Of Childhood, Austin Ambur, Timothy A. Nyckowski, Aashni Bhukhan

GME Publications

No abstract provided.


Back Matter Nov 2022

Back Matter

The Journal of Purdue Undergraduate Research

No abstract provided.


Alumni Spotlight: Jordyn (Mccord) Wintczak Nov 2022

Alumni Spotlight: Jordyn (Mccord) Wintczak

The Journal of Purdue Undergraduate Research

Jordyn (McCord) Wintczak published an article in volume 7 (2017) of the Journal of Purdue Undergraduate Research during her time spent completing her baccalaureate degree.


Alumni Spotlight: Stephanie Schramm Nov 2022

Alumni Spotlight: Stephanie Schramm

The Journal of Purdue Undergraduate Research

Stephanie Schramm published an article in volume 7 (2017) of the Journal of Purdue Undergraduate Research during her time spent completing her baccalaureate degree.


Alumni Spotlight: Karan Samel Nov 2022

Alumni Spotlight: Karan Samel

The Journal of Purdue Undergraduate Research

Karan Samel published an article in volume 7 (2017) of the Journal of Purdue Undergraduate Research during his time spent completing his baccalaureate degree.


Alumni Spotlight: Kathryn (Math) Florence Nov 2022

Alumni Spotlight: Kathryn (Math) Florence

The Journal of Purdue Undergraduate Research

Kathryn (Math) Florence published an article in volume 7 (2017) of the Journal of Purdue Undergraduate Research during her time spent completing her baccalaureate degree.


Alumni Spotlight: Hyesoo Chae Nov 2022

Alumni Spotlight: Hyesoo Chae

The Journal of Purdue Undergraduate Research

Hyesoo Chae published an article in volume 7 (2017) of the Journal of Purdue Undergraduate Research during her time spent completing her baccalaureate degree.


Interview: Danny Milisavljevic And Jack Reynolds, Catie Gilhooly Nov 2022

Interview: Danny Milisavljevic And Jack Reynolds, Catie Gilhooly

The Journal of Purdue Undergraduate Research

Dr. Danny Milisavljevic is an assistant professor of physics and astronomy at Purdue University. He works with motivated and enthusiastic supernova sleuths on his team actively investigating the catastrophic deaths of massive stars. Student researcher Jack Reynolds is interviewed along with Milisavljevic.


Interview: Cody Mullen, Catie Gilhooly Nov 2022

Interview: Cody Mullen, Catie Gilhooly

The Journal of Purdue Undergraduate Research

Dr. Cody Mullen is a clinical associate professor of public health and director of the Master of Health Administration (MHA) degree program at Purdue University. In this role, he works closely with industry partners, faculty, and students to deliver the MHA program.


Aerospace And Defense The Financial Impact Of Covid-19 On The Rolls-Royce Supply Chain, Khushboo Jain Nov 2022

Aerospace And Defense The Financial Impact Of Covid-19 On The Rolls-Royce Supply Chain, Khushboo Jain

The Journal of Purdue Undergraduate Research

After the pandemic hit in 2020, the aerospace and defense industry was specifically impacted very harshly. Rolls-Royce was one of the main companies that had to go through major structural and logistical changes to cope with the changing economy. As one of the leaders of the aerospace and defense (A&D) industry, the main problem that Rolls-Royce was facing was the drastic reduction in demand for civil and commercial aircraft, which was one of Rolls-Royce’s core businesses. This led to supply chain problems, reduced profits, and eventually heavy losses. The effects of these problems caused great distress in the company.

My …


Food For Local Benefit: Civic Agriculture At The Wea Creek Orchard, Reese Curtis Nov 2022

Food For Local Benefit: Civic Agriculture At The Wea Creek Orchard, Reese Curtis

The Journal of Purdue Undergraduate Research

Th is project is a case study on Wea Creek Orchard, an intergenerational farm in the greater Lafayette area. Because this was an ethnographic project based on grounded theory, I did not have a set research question upon entering the field. After spending a few months volunteering on the Wea Creek Orchard, however, I noticed that this farm operates in a community-oriented way, prioritizing community engagement over the pursuit of profit. With these observations as a base, this project reviews the ways in which Wea Creek Orchard runs its business as a civic agriculture operation. Civic agriculture refers to locally …


Global Governance Agenda-Setting On Big Tech, Amanda Shie Nov 2022

Global Governance Agenda-Setting On Big Tech, Amanda Shie

The Journal of Purdue Undergraduate Research

No abstract provided.


Applying The Byronic Model To The International Volunteers Of The Spanish Nationalists (1936–1939), Nathan Au Nov 2022

Applying The Byronic Model To The International Volunteers Of The Spanish Nationalists (1936–1939), Nathan Au

The Journal of Purdue Undergraduate Research

No abstract provided.


Polarimetric Radar And Vhf Lightning Observations In A Significantly Tornadic Supercell, Jacob Bruss Nov 2022

Polarimetric Radar And Vhf Lightning Observations In A Significantly Tornadic Supercell, Jacob Bruss

The Journal of Purdue Undergraduate Research

No abstract provided.


Modeling Scn2a Deficiency In Mice, Jacob Paulaskas Nov 2022

Modeling Scn2a Deficiency In Mice, Jacob Paulaskas

The Journal of Purdue Undergraduate Research

No abstract provided.


The Effect Of Fatty Acid Synthase (Fasn) Depletion In Pulmonary Metastatic Formation In Breast Cancer Murine Models, Zilin Xianyu Nov 2022

The Effect Of Fatty Acid Synthase (Fasn) Depletion In Pulmonary Metastatic Formation In Breast Cancer Murine Models, Zilin Xianyu

The Journal of Purdue Undergraduate Research

No abstract provided.


Comparison Of College Students’ Perspectives Of E-Cigarette Use And Major Of Study, Parker Woodruff Nov 2022

Comparison Of College Students’ Perspectives Of E-Cigarette Use And Major Of Study, Parker Woodruff

The Journal of Purdue Undergraduate Research

No abstract provided.


Assessing Availability And Effectiveness Of Pharmacy Spanish Interpreter Services: A Systematic Review, Ma. Emmanuelle R. Domingo Nov 2022

Assessing Availability And Effectiveness Of Pharmacy Spanish Interpreter Services: A Systematic Review, Ma. Emmanuelle R. Domingo

The Journal of Purdue Undergraduate Research

No abstract provided.


The Presence Of Microcystin In The Northwest Indiana Watershed, Breeann Mild Nov 2022

The Presence Of Microcystin In The Northwest Indiana Watershed, Breeann Mild

The Journal of Purdue Undergraduate Research

No abstract provided.


Investigating The Role Of The Hedgehog Pathway In Connection To Atrazine Endocrine Disruption, Anusha Kv Lakshmi Dharmavathi Nov 2022

Investigating The Role Of The Hedgehog Pathway In Connection To Atrazine Endocrine Disruption, Anusha Kv Lakshmi Dharmavathi

The Journal of Purdue Undergraduate Research

No abstract provided.


Developmental Behavioral Alterations Following Lead (Pb) Exposure In The Zebrafish Model System, Jenny Chen Nov 2022

Developmental Behavioral Alterations Following Lead (Pb) Exposure In The Zebrafish Model System, Jenny Chen

The Journal of Purdue Undergraduate Research

No abstract provided.


Microaggression Among Registered Nurses: An Exploratory Study, Saige Addison Nov 2022

Microaggression Among Registered Nurses: An Exploratory Study, Saige Addison

The Journal of Purdue Undergraduate Research

No abstract provided.


Exploring The Connections Between Students’ Social Justice And Mathematics Understandings, Lily Green Nov 2022

Exploring The Connections Between Students’ Social Justice And Mathematics Understandings, Lily Green

The Journal of Purdue Undergraduate Research

No abstract provided.