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A Phenomenological Study On Military Spouses Who Academically Persist To Graduation, Lasette Marie Doherty Dec 2022

A Phenomenological Study On Military Spouses Who Academically Persist To Graduation, Lasette Marie Doherty

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenology was to understand the supportive experiences of military spouse students who academically persist to graduation. The theory guiding this study was Bean and Metzner’s non-traditional undergraduate student attrition model. Drawing from House’s social support definition that defines different types of support, this study’s central research question asked what role support played in the academic persistence of undergraduate military spouses. Sub-questions asked how emotional and instrumental support affected academic persistence with military spouse students. How emotional and instrumental support affected academic persistence during military separations was also asked. Eleven current and past military spouse students …


Understanding Foster Care Elopement And Impact On Well-Being: A Phenomenological Study, Dana Monette Hart-Raynor Dec 2022

Understanding Foster Care Elopement And Impact On Well-Being: A Phenomenological Study, Dana Monette Hart-Raynor

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to understand how elopement behaviors impacted short- and long-term well-being and daily functioning of older youth participating in North Carolina’s Foster Care 18 to 21 Program and foster care alumni in North Carolina. The theories guiding this research study were Bowlby’s attachment theory, Bronfenbrenner’s ecological systems theory, and Maslow’s hierarchy of needs. Fragmented relationships with foster caregivers were intensified with frequent elopement behaviors and problematic interpersonal relationships continued to manifest after foster care exiting. Fostered youth, their caregivers, child welfare professionals, and the community-at-large were impacted by the youth’s decision to elope. The …


Jus Post Bellum And The Augustinian Worldview, Edward Anthony Herty Dec 2022

Jus Post Bellum And The Augustinian Worldview, Edward Anthony Herty

Doctoral Dissertations and Projects

Augustine of Hippo wrote a great deal regarding the subject of state-sponsored armed conflict. His views have been categorized into the concepts of jus ad bellum, jus in bello, and, more recently, jus post bellum. Jus ad bellum and jus in bello address the moral responsibilities of a nation and its sovereign as the decision to enter into conflict is made and as agents of the state endeavor to keep human suffering to a minimum. Jus post bellum is a more recent ideal that has, since World War I, addressed the need to establish a long-lasting peace upon the conclusion …


Tanf Work Policy Influences On Family Behaviors And Child Development, Robert William Sturgill Jr Dec 2022

Tanf Work Policy Influences On Family Behaviors And Child Development, Robert William Sturgill Jr

Doctoral Dissertations and Projects

There has been a lack of research on how work participation policies have impacted child development through their influences on family decisions. The purpose of this qualitative research study was to explore the perspectives of families toward TANF work participation policies, discover how those policies have influenced family behaviors, and analyze how those policy-behavior phenomena have impacted child development. First, the literature review showed that families with chronic welfare dependency had negative impacts on child development. The research showed that when TANF work participation policies were unenforced or income limits were too low, some recipients worked less and persisted in …


Evaluating The Uptake Of Cotesting And Guideline Adherent Cervical Cancer Screening And Reported Barriers To Guideline Adherence In Academic And Community Practice Settings: A Mixed Methods Study, Shahnaz Khan Dec 2022

Evaluating The Uptake Of Cotesting And Guideline Adherent Cervical Cancer Screening And Reported Barriers To Guideline Adherence In Academic And Community Practice Settings: A Mixed Methods Study, Shahnaz Khan

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Clinical practice screening guidelines recommend cotesting, a test that combines DNA Human Papillomavirus (HPV) testing with cervical cytology (also known as Pap testing) every 5-years, as a highly effective and preferred method for cervical cancer prevention among average-risk women aged 30-65. Up to date empirical data on the current uptake of this evidence-based intervention is sparse and does not allow for a complete understanding of the actual use of cotesting at the extended screening interval in practice among patients and providers in different types of practice settings. The 2012 national cervical cancer screening guidelines have further expanded in 2018 …


Skyler Pointer Art 399 Portfolio, Skyler Pointer Dec 2022

Skyler Pointer Art 399 Portfolio, Skyler Pointer

Professional Practices (ART 399)

In my work, I lean towards the idea that my art could make people think about others around them. I was mainly inspired to do this by a video I was shown in high school that basically encouraged people to try and put themselves in other peoples’ shoes. I tend to lean towards a cartoony art style because I would like to go into the animation industry and I also like to give my art a comedic tone to it. As a graphic designer, I like to utilize all the tools that I have learned throughout college. In terms of …


Answering The Call Dec 2022

Answering The Call

DePaul Magazine

With a strong spirit of service, DePaul initiatives aid displaced populations in Chicago and internationally.


The People's Advocate Dec 2022

The People's Advocate

DePaul Magazine

DePaul Magazine chats with Cook County Public Defender and DePaul alumnus Sharone Mitchell Jr. about his opinion on representing the underserved, the paths that shaped his career and the pursuit of justice for all.


Helping Dreams Take Flight Dec 2022

Helping Dreams Take Flight

DePaul Magazine

DePaul donor, alumna and corporate psychologist Becky Winkler establishes a scholarship to support equal access to education for underrepresented students in science, technology, engineering and math.


Make Room, Joseph Khabbaz Dec 2022

Make Room, Joseph Khabbaz

The Main Thing Devotional

And she brought forth her firstborn Son, and wrapped Him in swaddling cloths, and laid Him in a manger, because there was no room for them in the inn.” (Luke 2:7, NKJV)

There was no space for Jesus in the inn, so that He could provide a place for you with Him.


Placing The Cart Before The Horse: E-Records Policy Experiences And Lessons From Zimbabwe’S Provincial Government, Samson Mutsagondo, Petronella Katekwe Dec 2022

Placing The Cart Before The Horse: E-Records Policy Experiences And Lessons From Zimbabwe’S Provincial Government, Samson Mutsagondo, Petronella Katekwe

Library Philosophy and Practice (e-journal)

There is remarkable growth in use of electronic records in Zimbabwe. The professional management of such records is brought under spotlight as government ministries in the Midlands province of Zimbabwe manage electronic records without electronic records policies in place. The absence of electronic records policies implies lack of guidance regarding what should be done, how, when, why and by whom. The implementation of electronic records programmes in provincial government ministries before formulating and mobilising policies that guide such programmes is akin to placing the cart before the horse. Developing countries which face similar scenarios may take a leaf from the …


12/05/2022 Meeting, Kelleen Maluski Dec 2022

12/05/2022 Meeting, Kelleen Maluski

Meeting Minutes

No abstract provided.


Osteoarthritis: Multi-Ancestry Analysis Reveals Novel Genetic Loci Associated With The Disease, Jeff Hansen Dec 2022

Osteoarthritis: Multi-Ancestry Analysis Reveals Novel Genetic Loci Associated With The Disease, Jeff Hansen

Browse All News

No abstract provided.


Exposure Of Egyptian Rousette Bats (Rousettus Aegyptiacus) And A Little Free-Tailed Bat (Chaerephon Pumilus) To Alphaviruses In Uganda, Rebekah C. Kading, Erin M. Borland, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Jeremy P. Ledermann, Mary B. Crabtree, Nicholas A. Panella, Luke Nyakarahuka, Amy T. Gilbert, Julian C. Kerbis-Peterhans, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Barry R. Miller, Julius J. Lutwama, Robert M. Kityo, Ann M. Powers Dec 2022

Exposure Of Egyptian Rousette Bats (Rousettus Aegyptiacus) And A Little Free-Tailed Bat (Chaerephon Pumilus) To Alphaviruses In Uganda, Rebekah C. Kading, Erin M. Borland, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Jeremy P. Ledermann, Mary B. Crabtree, Nicholas A. Panella, Luke Nyakarahuka, Amy T. Gilbert, Julian C. Kerbis-Peterhans, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Barry R. Miller, Julius J. Lutwama, Robert M. Kityo, Ann M. Powers

United States Department of Agriculture Wildlife Services: Staff Publications

The reservoir for zoonotic o’nyong-nyong virus (ONNV) has remained unknown since this virus was first recognized in Uganda in 1959. Building on existing evidence for mosquito bloodfeeding on various frugivorous bat species in Uganda, and seroprevalence for arboviruses among bats in Uganda, we sought to assess if serum samples collected from bats in Uganda demonstrated evidence of exposure to ONNV or the closely related zoonotic chikungunya virus (CHIKV). In total, 652 serum samples collected from six bat species were tested by plaque reduction neutralization test (PRNT) for neutralizing antibodies against ONNV and CHIKV. Forty out of 303 (13.2%) Egyptian rousettes …


Grief During Holidays: Stages, Types And Coping Tips, Tehreem Khan Dec 2022

Grief During Holidays: Stages, Types And Coping Tips, Tehreem Khan

Browse All News

No abstract provided.


Effects Of Antecedent Precipitation Amount And Covid-19 Lockdown On Water Quality Along An Urban Gradient, Daniel Ramirez, Heejun Chang, Katherine Gelsey Dec 2022

Effects Of Antecedent Precipitation Amount And Covid-19 Lockdown On Water Quality Along An Urban Gradient, Daniel Ramirez, Heejun Chang, Katherine Gelsey

Geography Faculty Publications and Presentations

Water quality is affected by multiple spatial and temporal factors, including the surrounding land characteristics, human activities, and antecedent precipitation amounts. However, identifying the relationships between water quality and spatially and temporally varying environmental variables with a machine learning technique in a heterogeneous urban landscape has been understudied. We explore how seasonal and variable precipitation amounts and other small-scale landscape variables affect E. coli, total suspended solids (TSS), nitrogen-nitrate, orthophosphate, lead, and zinc concentrations in Portland, Oregon, USA. Mann–Whitney tests were used to detect differences in water quality between seasons and COVID-19 periods. Spearman’s rank correlation analysis was used to …


Ndls Communicator: Week Of 12.05.22, Notre Dame Law School Dec 2022

Ndls Communicator: Week Of 12.05.22, Notre Dame Law School

NDLS Communicator

The Latest News

  • Professor Emily Bremer wins Emerging Scholar Award from AALS
  • Dublin and Hamburg Honor Scholars Programs offer unique opportunities for students to learn international law
  • Notre Dame recognized as top LL.M. Human Rights Law Program
  • Religious Liberty Initiative mentioned in article about Ohio EdChoice debate
  • Mary Ellen O'Connell was quoted in The Intercept article, "Will Biden Sell Advanced Drones to Ukraine?"
  • Jimmy Gurulé was quoted by the Washington Post in "Sedition trial win bolsters Justice Dept. in Jan. 6 probe."
  • Avishalom Tor has published a new article, "The Law and Economics of Behavioral Regulation," 18 Review of Law …


Symptom-Driven Inhaled Corticosteroid/Long-Acting Beta-Agonist Therapy For Adult Patients With Asthma Who Are Non-Adherent To Daily Maintenance Inhalers: A Study Protocol For A Pragmatic Randomized Controlled Trial, James G Krings, Kaitlyn M Wojcik, Vanessa Chen, Tejas C Sekhar, Kelly Harris, Abigail Zulich, Kaharu Sumino, Ross Brownson, Eric Lenze, Mario Castro Dec 2022

Symptom-Driven Inhaled Corticosteroid/Long-Acting Beta-Agonist Therapy For Adult Patients With Asthma Who Are Non-Adherent To Daily Maintenance Inhalers: A Study Protocol For A Pragmatic Randomized Controlled Trial, James G Krings, Kaitlyn M Wojcik, Vanessa Chen, Tejas C Sekhar, Kelly Harris, Abigail Zulich, Kaharu Sumino, Ross Brownson, Eric Lenze, Mario Castro

2020-Current year OA Pubs

BACKGROUND: While inhaled corticosteroids (ICS) are considered the essential foundation of most asthma therapy, ICS inhaler nonadherence is a notoriously common problem and a significant cause of asthma-related morbidity. Partially acknowledging the problem of nonadherence, international organizations recently made paradigm-shifting recommendations that all patients with mild-to-moderate persistent asthma be considered for symptom-driven ICS-containing inhalers rather than relying on adherence to traditional maintenance ICS inhalers and symptom-driven short-acting beta-agonists (SABA). With this new approach, asthma patients are at least exposed to the important anti-inflammatory effects of ICS-containing inhalers when their symptom reliever inhaler is deployed due to acute symptoms.

METHODS: This …


Pyridine Modifications Regulate The Electronics And Reactivity Of Fe–Pyridinophane Complexes, Magy A. Mekhail, Kristof Pota, Sugam Kharel, David M. Freire, Kayla N. Green Dec 2022

Pyridine Modifications Regulate The Electronics And Reactivity Of Fe–Pyridinophane Complexes, Magy A. Mekhail, Kristof Pota, Sugam Kharel, David M. Freire, Kayla N. Green

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

12-Membered pyridinophanes are the focus of many studies as biological mimics, chelators, and catalytic precursors. Therefore, the desire to tune the reactivity of pyridinophanes to better control the applications of derivative metal complexes has inspired many structure–activity relationship studies. However, the separation of structural versus electronic changes imparted by ligand modification has made these structure–activity relationship studies of transition metal catalysts challenging to define. In this work we show that 4-substitution of the pyridine ring in 12-membered tetra-aza pyridinophanes successfully provides a regulatory handle on the electronic properties of the metal center and, therefore, the catalytic C–C coupling activity of …


Probing Conformational Landscapes And Mechanisms Of Allosteric Communication In The Functional States Of The Abl Kinase Domain Using Multiscale Simulations And Network-Based Mutational Profiling Of Allosteric Residue Potentials, Keerthi Krishnan, Hao Tian, Peng Tao, Gennady M. Verkhivker Dec 2022

Probing Conformational Landscapes And Mechanisms Of Allosteric Communication In The Functional States Of The Abl Kinase Domain Using Multiscale Simulations And Network-Based Mutational Profiling Of Allosteric Residue Potentials, Keerthi Krishnan, Hao Tian, Peng Tao, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

In the current study, multiscale simulation approaches and dynamic network methods are employed to examine the dynamic and energetic details of conformational landscapes and allosteric interactions in the ABL kinase domain that determine the kinase functions. Using a plethora of synergistic computational approaches, we elucidate how conformational transitions between the active and inactive ABL states can employ allosteric regulatory switches to modulate intramolecular communication networks between the ATP site, the substrate binding region, and the allosteric binding pocket. A perturbation-based network approach that implements mutational profiling of allosteric residue propensities and communications in the ABL states is proposed. Consistent with …


Students To Graduate At Fall Commencement Ceremonies This Weekend, Jessica Spivey Dec 2022

Students To Graduate At Fall Commencement Ceremonies This Weekend, Jessica Spivey

Lindenlink (2012- )

No abstract provided.


Federated Learning Enables Big Data For Rare Cancer Boundary Detection, Sarthak Pati, Ujjwal Baid, Brandon Edwards, Micah Sheller, Shih-Han Wang, Patrick Foley, Deepthi Karkada, Christos Davatzikos, Chiharu Sako, Satyam Ghodasara, Michel Bilello, Suyash Mohan, Philipp Vollmuth, Gianluca Brugnara, Chandrakanth J Preetha, Felix Sahm, Klaus Maier-Hein, Maximilian Zenk, Martin Bendszus, Wolfgang Wick, Evan Calabrese, Jeffrey Rudie, Javier Villanueva-Meyer, Soonmee Cha, Madhura Ingalhalikar, Manali Jadhav, Umang Pandey, Jitender Saini, John Garrett, Matthew Larson, Robert Jeraj, Stuart Currie, Russell Frood, Kavi Fatania, Raymond Y Huang, Ken Chang, Carmen Balaña, Jaume Capellades, Josep Puig, Johannes Trenkler, Josef Pichler, Georg Necker, Andreas Haunschmidt, Stephan Meckel, Gaurav Shukla, Spencer Liem, Gregory S Alexander, Joseph Lombardo, Joshua D Palmer, Adam E Flanders, Adam P Dicker, Haris I Sair, Craig K Jones, Archana Venkataraman, Meirui Jiang, Tiffany Y So, Cheng Chen, Pheng Ann Heng, Qi Dou, Michal Kozubek, Filip Lux, Jan Michálek, Petr Matula, Miloš Keřkovský, Tereza Kopřivová, Marek Dostál, Václav Vybíhal, Michael A Vogelbaum, J Ross Mitchell, Joaquim Farinhas, Joseph A Maldjian, Chandan Ganesh Bangalore Yogananda, Marco C Pinho, Divya Reddy, James Holcomb, Benjamin C Wagner, Benjamin M Ellingson, Timothy F Cloughesy, Catalina Raymond, Talia Oughourlian, Akifumi Hagiwara, Chencai Wang, Minh-Son To, Sargam Bhardwaj, Chee Chong, Marc Agzarian, Alexandre Xavier Falcão, Samuel B Martins, Bernardo C A Teixeira, Flávia Sprenger, David Menotti, Diego R Lucio, Pamela Lamontagne, Daniel Marcus, Benedikt Wiestler, Florian Kofler, Ivan Ezhov, Marie Metz, Rajan Jain, Matthew Lee, Yvonne W Lui, Richard Mckinley, Johannes Slotboom, Piotr Radojewski, Raphael Meier, Roland Wiest, Derrick Murcia, Eric Fu, Rourke Haas, John Thompson, David Ryan Ormond, Chaitra Badve, Andrew E Sloan, Vachan Vadmal, Kristin Waite, Rivka R Colen, Linmin Pei, Murat Ak, Ashok Srinivasan, J Rajiv Bapuraj, Arvind Rao, Nicholas Wang, Ota Yoshiaki, Toshio Moritani, Sevcan Turk, Joonsang Lee, Snehal Prabhudesai, Fanny Morón, Jacob Mandel, Konstantinos Kamnitsas, Ben Glocker, Luke V M Dixon, Matthew Williams, Peter Zampakis, Vasileios Panagiotopoulos, Panagiotis Tsiganos, Sotiris Alexiou, Ilias Haliassos, Evangelia I Zacharaki, Konstantinos Moustakas, Christina Kalogeropoulou, Dimitrios M Kardamakis, Yoon Seong Choi, Seung-Koo Lee, Jong Hee Chang, Sung Soo Ahn, Bing Luo, Laila Poisson, Ning Wen, Pallavi Tiwari, Ruchika Verma, Rohan Bareja, Ipsa Yadav, Jonathan Chen, Neeraj Kumar, Marion Smits, Sebastian R Van Der Voort, Ahmed Alafandi, Fatih Incekara, Maarten M J Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W Schouten, Hendrikus J Dubbink, Arnaud J P E Vincent, Martin J Van Den Bent, Pim J French, Stefan Klein, Yading Yuan, Sonam Sharma, Tzu-Chi Tseng, Saba Adabi, Simone P Niclou, Olivier Keunen, Ann-Christin Hau, Martin Vallières, David Fortin, Martin Lepage, Bennett Landman, Karthik Ramadass, Kaiwen Xu, Silky Chotai, Lola B Chambless, Akshitkumar Mistry, Reid C Thompson, Yuriy Gusev, Krithika Bhuvaneshwar, Anousheh Sayah, Camelia Bencheqroun, Anas Belouali, Subha Madhavan, Thomas C Booth, Alysha Chelliah, Marc Modat, Haris Shuaib, Carmen Dragos, Aly Abayazeed, Kenneth Kolodziej, Michael Hill, Ahmed Abbassy, Shady Gamal, Mahmoud Mekhaimar, Mohamed Qayati, Mauricio Reyes, Ji Eun Park, Jihye Yun, Ho Sung Kim, Abhishek Mahajan, Mark Muzi, Sean Benson, Regina G H Beets-Tan, Jonas Teuwen, Alejandro Herrera-Trujillo, Maria Trujillo, William Escobar, Ana Abello, Jose Bernal, Jhon Gómez, Joseph Choi, Stephen Baek, Yusung Kim, Heba Ismael, Bryan Allen, John M Buatti, Aikaterini Kotrotsou, Hongwei Li, Tobias Weiss, Michael Weller, Andrea Bink, Bertrand Pouymayou, Hassan F Shaykh, Joel Saltz, Prateek Prasanna, Sampurna Shrestha, Kartik M Mani, David Payne, Tahsin Kurc, Enrique Pelaez, Heydy Franco-Maldonado, Francis Loayza, Sebastian Quevedo, Pamela Guevara, Esteban Torche, Cristobal Mendoza, Franco Vera, Elvis Ríos, Eduardo López, Sergio A Velastin, Godwin Ogbole, Mayowa Soneye, Dotun Oyekunle, Olubunmi Odafe-Oyibotha, Babatunde Osobu, Mustapha Shu'aibu, Adeleye Dorcas, Farouk Dako, Amber L Simpson, Mohammad Hamghalam, Jacob J Peoples, Ricky Hu, Anh Tran, Danielle Cutler, Fabio Y Moraes, Michael A Boss, James Gimpel, Deepak Kattil Veettil, Kendall Schmidt, Brian Bialecki, Sailaja Marella, Cynthia Price, Lisa Cimino, Charles Apgar, Prashant Shah, Bjoern Menze, Jill S Barnholtz-Sloan, Jason Martin, Spyridon Bakas Dec 2022

Federated Learning Enables Big Data For Rare Cancer Boundary Detection, Sarthak Pati, Ujjwal Baid, Brandon Edwards, Micah Sheller, Shih-Han Wang, Patrick Foley, Deepthi Karkada, Christos Davatzikos, Chiharu Sako, Satyam Ghodasara, Michel Bilello, Suyash Mohan, Philipp Vollmuth, Gianluca Brugnara, Chandrakanth J Preetha, Felix Sahm, Klaus Maier-Hein, Maximilian Zenk, Martin Bendszus, Wolfgang Wick, Evan Calabrese, Jeffrey Rudie, Javier Villanueva-Meyer, Soonmee Cha, Madhura Ingalhalikar, Manali Jadhav, Umang Pandey, Jitender Saini, John Garrett, Matthew Larson, Robert Jeraj, Stuart Currie, Russell Frood, Kavi Fatania, Raymond Y Huang, Ken Chang, Carmen Balaña, Jaume Capellades, Josep Puig, Johannes Trenkler, Josef Pichler, Georg Necker, Andreas Haunschmidt, Stephan Meckel, Gaurav Shukla, Spencer Liem, Gregory S Alexander, Joseph Lombardo, Joshua D Palmer, Adam E Flanders, Adam P Dicker, Haris I Sair, Craig K Jones, Archana Venkataraman, Meirui Jiang, Tiffany Y So, Cheng Chen, Pheng Ann Heng, Qi Dou, Michal Kozubek, Filip Lux, Jan Michálek, Petr Matula, Miloš Keřkovský, Tereza Kopřivová, Marek Dostál, Václav Vybíhal, Michael A Vogelbaum, J Ross Mitchell, Joaquim Farinhas, Joseph A Maldjian, Chandan Ganesh Bangalore Yogananda, Marco C Pinho, Divya Reddy, James Holcomb, Benjamin C Wagner, Benjamin M Ellingson, Timothy F Cloughesy, Catalina Raymond, Talia Oughourlian, Akifumi Hagiwara, Chencai Wang, Minh-Son To, Sargam Bhardwaj, Chee Chong, Marc Agzarian, Alexandre Xavier Falcão, Samuel B Martins, Bernardo C A Teixeira, Flávia Sprenger, David Menotti, Diego R Lucio, Pamela Lamontagne, Daniel Marcus, Benedikt Wiestler, Florian Kofler, Ivan Ezhov, Marie Metz, Rajan Jain, Matthew Lee, Yvonne W Lui, Richard Mckinley, Johannes Slotboom, Piotr Radojewski, Raphael Meier, Roland Wiest, Derrick Murcia, Eric Fu, Rourke Haas, John Thompson, David Ryan Ormond, Chaitra Badve, Andrew E Sloan, Vachan Vadmal, Kristin Waite, Rivka R Colen, Linmin Pei, Murat Ak, Ashok Srinivasan, J Rajiv Bapuraj, Arvind Rao, Nicholas Wang, Ota Yoshiaki, Toshio Moritani, Sevcan Turk, Joonsang Lee, Snehal Prabhudesai, Fanny Morón, Jacob Mandel, Konstantinos Kamnitsas, Ben Glocker, Luke V M Dixon, Matthew Williams, Peter Zampakis, Vasileios Panagiotopoulos, Panagiotis Tsiganos, Sotiris Alexiou, Ilias Haliassos, Evangelia I Zacharaki, Konstantinos Moustakas, Christina Kalogeropoulou, Dimitrios M Kardamakis, Yoon Seong Choi, Seung-Koo Lee, Jong Hee Chang, Sung Soo Ahn, Bing Luo, Laila Poisson, Ning Wen, Pallavi Tiwari, Ruchika Verma, Rohan Bareja, Ipsa Yadav, Jonathan Chen, Neeraj Kumar, Marion Smits, Sebastian R Van Der Voort, Ahmed Alafandi, Fatih Incekara, Maarten M J Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W Schouten, Hendrikus J Dubbink, Arnaud J P E Vincent, Martin J Van Den Bent, Pim J French, Stefan Klein, Yading Yuan, Sonam Sharma, Tzu-Chi Tseng, Saba Adabi, Simone P Niclou, Olivier Keunen, Ann-Christin Hau, Martin Vallières, David Fortin, Martin Lepage, Bennett Landman, Karthik Ramadass, Kaiwen Xu, Silky Chotai, Lola B Chambless, Akshitkumar Mistry, Reid C Thompson, Yuriy Gusev, Krithika Bhuvaneshwar, Anousheh Sayah, Camelia Bencheqroun, Anas Belouali, Subha Madhavan, Thomas C Booth, Alysha Chelliah, Marc Modat, Haris Shuaib, Carmen Dragos, Aly Abayazeed, Kenneth Kolodziej, Michael Hill, Ahmed Abbassy, Shady Gamal, Mahmoud Mekhaimar, Mohamed Qayati, Mauricio Reyes, Ji Eun Park, Jihye Yun, Ho Sung Kim, Abhishek Mahajan, Mark Muzi, Sean Benson, Regina G H Beets-Tan, Jonas Teuwen, Alejandro Herrera-Trujillo, Maria Trujillo, William Escobar, Ana Abello, Jose Bernal, Jhon Gómez, Joseph Choi, Stephen Baek, Yusung Kim, Heba Ismael, Bryan Allen, John M Buatti, Aikaterini Kotrotsou, Hongwei Li, Tobias Weiss, Michael Weller, Andrea Bink, Bertrand Pouymayou, Hassan F Shaykh, Joel Saltz, Prateek Prasanna, Sampurna Shrestha, Kartik M Mani, David Payne, Tahsin Kurc, Enrique Pelaez, Heydy Franco-Maldonado, Francis Loayza, Sebastian Quevedo, Pamela Guevara, Esteban Torche, Cristobal Mendoza, Franco Vera, Elvis Ríos, Eduardo López, Sergio A Velastin, Godwin Ogbole, Mayowa Soneye, Dotun Oyekunle, Olubunmi Odafe-Oyibotha, Babatunde Osobu, Mustapha Shu'aibu, Adeleye Dorcas, Farouk Dako, Amber L Simpson, Mohammad Hamghalam, Jacob J Peoples, Ricky Hu, Anh Tran, Danielle Cutler, Fabio Y Moraes, Michael A Boss, James Gimpel, Deepak Kattil Veettil, Kendall Schmidt, Brian Bialecki, Sailaja Marella, Cynthia Price, Lisa Cimino, Charles Apgar, Prashant Shah, Bjoern Menze, Jill S Barnholtz-Sloan, Jason Martin, Spyridon Bakas

Faculty, Staff and Student Publications

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically …


Executive Summary Of The American Radium Society Appropriate Use Criteria For Management Of Uterine Clear Cell And Serous Carcinomas, Tracy Sherertz, Anuja Jhingran, Matthew Biagioli, David Gaffney, Mohamed Elshaikh, Matthew Harkenrider, Shruti Jolly, Catheryn Yashar, Lorraine Portelance, Andrew Wahl, Aradhana Venkatesan, Linna Li, William Small, American Radium Society Dec 2022

Executive Summary Of The American Radium Society Appropriate Use Criteria For Management Of Uterine Clear Cell And Serous Carcinomas, Tracy Sherertz, Anuja Jhingran, Matthew Biagioli, David Gaffney, Mohamed Elshaikh, Matthew Harkenrider, Shruti Jolly, Catheryn Yashar, Lorraine Portelance, Andrew Wahl, Aradhana Venkatesan, Linna Li, William Small, American Radium Society

Faculty, Staff and Student Publications

Background: Uterine clear cell and serous carcinomas have a high propensity for locoregional and distant spread, tend to be more advanced at presentation, and carry a higher risk of recurrence and death than endometrioid cancers. Limited prospective data exist to guide evidence-based management of these rare malignancies.

Objective: The American Radium Society sought to summarize evidence-based guidelines developed by a multidisciplinary expert panel that help to guide the management of uterine clear cell and serous carcinomas.

Methods: The American Radium Society Appropriate Use Criteria presented in this manuscript were developed by a multidisciplinary expert panel using an extensive analysis of …


Temporal And Spatial Metabolite Dynamics Impart Control In Adipogenesis, Kristin Eckel-Mahan Dec 2022

Temporal And Spatial Metabolite Dynamics Impart Control In Adipogenesis, Kristin Eckel-Mahan

Faculty, Staff and Student Publications

The process of adipogenesis is critical for forming new, healthy adipocytes that are capable of storing lipids. In this issue, Sánchez-Ramírez and Ung et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202111137) reveal a novel role for the metabolite nicotinamide adenine dinucleotide in controlling differentiation of mesenchymal stromal cells into adipocytes.


Selective Vulnerability Of The Intermediate Retinal Capillary Plexus Precedes Retinal Ganglion Cell Loss In Ocular Hypertension, Maria Polo-Prieto, Yong H Park, Solomon E Gibson, Peter D Westenskow, Roomasa Channa, Benjamin J Frankfort Dec 2022

Selective Vulnerability Of The Intermediate Retinal Capillary Plexus Precedes Retinal Ganglion Cell Loss In Ocular Hypertension, Maria Polo-Prieto, Yong H Park, Solomon E Gibson, Peter D Westenskow, Roomasa Channa, Benjamin J Frankfort

Faculty, Staff and Students Publications

Introduction: Glaucoma, a disease of retinal ganglion cell (RGC) injury and potentially devastating vision loss, is associated with both ocular hypertension (OHT) and reduced ocular blood flow. However, the relationship between OHT and retinal capillary architecture is not well understood. In this project, we studied microvasculature damage in mice exposed to mild levels of induced OHT.

Methods: Mild OHT was induced with the microbead model for 2 weeks. At this time point, some retinas were immunostained with CD31 (endothelium), Collagen IV (basement membrane), and RBPMS (RGCs) for z-stack confocal microscopy. We processed these confocal images to distinguish the three retinal …


A Cross-Sectional Study Of The Prevalence Of Anal Dysplasia Among Women With High-Grade Cervical, Vaginal, And Vulvar Dysplasia Or Cancer: The Panda Study, Ming Guo, Mark F Munsell, Joel Fokom-Domgue, Mila Salcedo, Ashish Deshmukh, Kristina R Dahlstrom, Mallory Ogburn, Anthony Price, Nicole D Fleming, Jolyn Taylor, Aaron Shafer, Lauren Cobb, Keith Sigel, Erich M Sturgis, Elizabeth Y Chiao, Kathleen M Schmeler Dec 2022

A Cross-Sectional Study Of The Prevalence Of Anal Dysplasia Among Women With High-Grade Cervical, Vaginal, And Vulvar Dysplasia Or Cancer: The Panda Study, Ming Guo, Mark F Munsell, Joel Fokom-Domgue, Mila Salcedo, Ashish Deshmukh, Kristina R Dahlstrom, Mallory Ogburn, Anthony Price, Nicole D Fleming, Jolyn Taylor, Aaron Shafer, Lauren Cobb, Keith Sigel, Erich M Sturgis, Elizabeth Y Chiao, Kathleen M Schmeler

Faculty, Staff and Students Publications

BACKGROUND: High-risk human papillomavirus (HR-HPV) infection is a risk factor for anal cancer, yet no anal cancer screening guidelines exist for women with lower genital tract HPV-related disease. We sought to describe the prevalence of anal HR-HPV or cytologic abnormalities in such women.

METHODS: This cross-sectional study was performed between October 2018 and December 2021. Inclusion criteria were ≥21 years of age and a prior diagnosis of high-grade dysplasia/cancer of the cervix, vagina, or vulva. Participants underwent anal cytology and anal/cervicovaginal HR-HPV testing. Women with abnormal anal cytology were referred for high-resolution anoscopy (HRA).

RESULTS: 324 evaluable women were enrolled. …


A Phenomenological Study On Trauma And Binge Eating Disorder Among African American Women In The State Of Virginia, Vester Appiah Dec 2022

A Phenomenological Study On Trauma And Binge Eating Disorder Among African American Women In The State Of Virginia, Vester Appiah

Doctoral Dissertations and Projects

The primary goal of this research was to investigate trauma and binge eating disorders among African American women. This study is related to numerous research assessments on disordered eating even though they have majorly focused on binge eating among European American women, thus ignoring the African Americans. However, the investigation aimed to build on the previous research studies by conducting a more in-depth exploration of the adverse impact experienced by the minority groups and how traumatic events contribute to the situation. Besides, culturally specific models of binge eating among African American women were conducted in trauma survivors and possible mechanisms …


Mental Health Implications Of Isolation During Hospitalization For Covid-19: Self-Perceived Variations In Emotion, Rebekah Ruth Jones Dec 2022

Mental Health Implications Of Isolation During Hospitalization For Covid-19: Self-Perceived Variations In Emotion, Rebekah Ruth Jones

Doctoral Dissertations and Projects

Forced isolation due to the COVID-19 pandemic has resulted in numerous mental health consequences. Individuals who have required hospitalization due to contracting the illness are at an increased risk of developing potentially harmful mental health concerns resulting from the emotional distress of forced isolation. Families separated from one another experience anxiety and fear due to helplessness fostered by the separation. Furthermore, medical caretakers are placed in the position to make life-altering decisions for their patients, increasing their stress and anxiety levels. Therefore, it is imperative that hospitals provide adequate mental health support for patients and their family members. Furthermore, communities …


A Multi-Site Case Study Of Christian School Leaders And Teachers Who Provide A Welcoming And Inclusive Environment For Students From Low Ses Backgrounds And/Or With Learning Differences, Amanda Blake Champion Dec 2022

A Multi-Site Case Study Of Christian School Leaders And Teachers Who Provide A Welcoming And Inclusive Environment For Students From Low Ses Backgrounds And/Or With Learning Differences, Amanda Blake Champion

Doctoral Dissertations and Projects

The purpose of this multi-site case study was to examine the intentional practices of Christian school leaders and teachers who strive to provide a welcoming and inclusive environment for students from low-socioeconomic (SES) backgrounds and/or with learning differences. The theory guiding this study is Bandura’s social cognitive theory. It connects the beliefs of self-efficacy held by school leaders and teachers to their values and philosophies, and their capability to include and welcome students from low SES backgrounds and/or with learning differences. This study investigated how school leaders and teachers welcome and include students from low SES backgrounds and/or with learning …


A Biblical Theology Of Water, Eric Robert Waller Dec 2022

A Biblical Theology Of Water, Eric Robert Waller

Doctoral Dissertations and Projects

Numerous “water related terms” are utilized in Genesis 1-2 such as, “the deep, “the waters,” “water,” “sea,” seas,” “stream,” “river,” “flow,” “flows,” and “rain.” Arguably similar, Revelation 21-22 uses the terms “water of life,” “river of the water of life,” “thirsty,” “spring, ” and “lake.” That the traditional Protestant canon is bookended with such similar terminology appears to create an inclusio that demands further inquiry within the canon to seek supplemental, complementary, and even potentially contrasting and conflicting evidence supporting a biblical theology of water. While commentary on every canonical water related text or term would be a daunting task …