Digital Commons Network^™

Tennessee State Museum Summer 2025 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Tennessee State Museum Spring 2025 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Tennessee State Museum Fall 2024 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Tennessee State Museum Summer 2024 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Tennessee State Museum Spring 2024 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Tennessee State Museum Fall-Winter 2023/24 Newsletter & Calendar Of Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

2025 Traumatic Brain Injury Annual Report, Tennessee. Department Of Health.

Traumatic Brain Injury Annual Report

No abstract provided.

Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss

Progress in Scale Modeling, an International Journal

The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.

Polyherbal Phytochemicals As Multi-Target Inhibitors Of Key Breast Cancer Proteins: A Computational Approach, Nadia Wahyuningsih, Nashi Widodo, Sri Rahayu, Muhaimin Rifa’I

Karbala International Journal of Modern Science

Breast cancer is a primary worldwide health concern, and conventional therapies often cause side effects. This study was performed to investigate the therapeutic potential of a polyherbal formulation containing Curcuma longa, Phyllanthus niruri, Ziziphus mauritiana, Nigella sativa, and Annona muricata as multi-target inhibitors against breast cancer protein targets using molecular docking and molecular dynamics in silico approach. Bioactive compounds were analyzed using Liquid Chromatography High-Resolution Mass Spectrometry (LC-HRMS) to identify the extract's phytochemicals. The compounds were examined for drug-likeness, membrane permeability, bioactivity, and toxicity. The inhibitory ability against the proto-oncogene pathway, which is commonly dysregulated and mutated in breast cancer, …

Synthesis And Characterization Of Ti-Enhanced F75/Ha Functionally Graded Materials Fabricated By Powder Metallurgy, Afrah M. Al Hussainey, Aseel Mustafa, Randa Kamel Hussain

Karbala International Journal of Modern Science

Functionally graded materials (FGMs) are a highly advanced class of biomaterials with graded structure and properties, enabling the fabrication of physiologically and mechanically compatible materials for use in various medical devices. This study aims to produce a functional-grade material based on a cobalt-chromium-molybdenum alloy (F75) reinforced with 4% titanium (Ti) and hydroxyapatite (HA). This will enhance the material's mechanical properties, corrosion resistance, and bioactivity, making it suitable for use as a bone substitute. The natural eggshells were washed, burnt, and chemically processed to form hydroxyapatite with a Ca/P proportion of 1.67. FTIR showed that phosphate and OH groups were separate, …

The Effectiveness Of Wordwall-Integrated Game-Based Learning On Elementary School Students' Science And Social Studies (Ipas) Learning Outcomes, Maryanah Maryanah, Aynin Mashfufah, Riska Pristiani

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

The implementation of IPAS learning at the elementary school level is still dominated by one-way learning strategies with limited media support. This condition has an impact on the low level of student activity, resulting in suboptimal conceptual understanding, especially for abstract material such as food chains. This study aims to examine the effect of applying digital game-based learning integrated with Wordwall on the IPAS learning outcomes of fifth-grade elementary school students. The research used a quantitative approach with a quasi-experimental design, involving a treatment group and a comparison group with equivalent initial abilities. Data collection was carried out using a …

Stuck In The Dark: No Association Between Light, Sound, And Delirium In The Picu, Kara Greenfield, Oliver Karam, A. M. Iqbal O’Meara

Journal of Pediatric Intensive Care

Objectives: The purpose of this study was to evaluate the association between sound and light variables and development of delirium in pediatric intensive care unit (PICU) patients within the subsequent three days. Methods: Light and sound were continuously measured, and patient-specific data was collected daily. Outcomes included presence of delirium, determined by Cornell Assessment of Pediatric Delirium (CAPD) score ≥ 9 on at least one day, and development of delirium in the subsequent 3 days. Results: 142 patients were enrolled, totaling 896 study days. Delirium prevalence was 31%. Neurologic diagnosis, younger age, longer PICU stay, restraints, benzodiazepines, opiate infusion, and …

The Association Of Bedside Nurse Staffing On Patient Outcomes And Throughput In A Pediatric Cardiac Intensive Care Unit, Michael P. Fundora, Jiayi Liu, Diwas Kc, Christina Calamaro

Journal of Pediatric Intensive Care

Objective: Healthcare throughput is the progression of patients from admission to discharge, limited by bed occupancy and hospital capacity. This study examines Heart Center throughput, cascading effects of limited beds, transfer delays, and nursing staffing on outcomes utilizing elective surgery cancellation during the initial SARS-CoV-2 pandemic wave. Design: Retrospective single-center study of staffing, adverse events, and transfers were collected. Study period was January 1, 2018 – December 31, 2020 with the SARS-CoV-2 period March-May 2020. Main Results: There were 2,589 patients, median age 5 months (6 days-4 years), 1,543 (60%) surgical, 1,046 (40%) medical. Mortality was 3.9% (n=101), median stay …

Outcomes Associated With A Pediatric Intensive Care Unit Sedation Weaning Protocol, Kimberley Harper, Jessica Anderson, Julie S. Pingel, Katharine Boyle, Li Wang, Christopher J. Lindsell, Ann Sweeney, Kristina A. Betters

Journal of Pediatric Intensive Care

Objective: To compare patient outcomes before and after implementation of a risk stratified pediatric sedation weaning protocol. Methods: This observational cohort study, in a 30-bed tertiary care pediatric intensive care unit (PICU), included patients requiring opioid, benzodiazepine and/or dexmedetomidine infusions. Outcomes (duration of wean, PICU length of stay (LOS), and withdrawal assessment tool (WAT-1) scores) were collected by retrospective chart review for 12-months before and after protocol implementation. The influence of the protocol was assessed using an interrupted time series analysis (ITS). Results: There were 49 patients before and 47 patients after protocol implementation. Median opioid wean duration pre-protocol was …

Neutrophil Lymphocyte Ratio And Platelet Lymphocyte Ratio As Predictors Of Disease Severity And Mortality In Critically Ill Children: A Retrospective Cohort Study, Sangeetha Shenoy, Shruti Patil

Journal of Pediatric Intensive Care

Objectives: The aim of this study was to determine the ability of Neutrophil lymphocyte ratio and Platelet lymphocyte ratio to predict severity of illness as assessed by 2 scoring systems, namely, Pediatric Logistic Organ Dysfunction-2(PELOD-2) and Pediatric Risk of Mortality-III(PRISM-III) and outcome. Methods: This was a retrospective cohort study wherein all critically ill children aged 1month to 18years admitted in pediatric intensive care unit from January 2021 to October 2022 were included. Children with chronic systemic diseases and with hematological illness were excluded from the study. Demographic details, diagnosis, PRISM-III-24 and PELOD-2 scores at admission and outcome were retrieved from …

Fluid Removal In Children On Continuous Renal Replacement Therapy Improves Organ Dysfunction Score, Sachin D. Tadphale, Peter M. Luckett, Raymond P. Quigley, Archana V. Dhar, Diane K. Gollhofer, Vinai Modem

Journal of Pediatric Intensive Care

Objectives: To assess impact of fluid removal on improvement in organ function in children who received continuous renal replacement therapy (CRRT) for management of acute kidney injury (AKI) and/or fluid overload (FO). Methods: A retrospective review of eligible patients admitted to a tertiary level intensive care unit over a 3-year period was performed. Improvement in non-renal organ function, the primary outcome, was defined as decrease in non-renal component of Pediatric Logistic Organ Dysfunction (PELOD) score on day 3 of CRRT. The cohort was categorized into Group 1 (improvement) and Group 2 (no improvement or worsening) in non-renal PELOD score. Multivariable …

Descriptive And Clinical Characteristics Of Non-Survivors In A Tertiary Pediatric Intensive Care Unit In Turkey: 6 Years Of Experience, Zeynep Karakaya, Merve Boyraz, Seyma Koksal Atis, Servet Yuce, Muhterem Duyu

Journal of Pediatric Intensive Care

Objectives: To identify the characteristics of non-survivors in a pediatric intensive care unit (PICU) in Turkey. Methods: This is a retrospective analysis of patients who died in a tertiary PICU over a 6-year period from 2016 to 2021. Data were drawn from electronic medical records and resuscitation notes. Mode of death was categorized as failed cardiopulmonary resuscitation (F-CPR) or brain death (BD). Results: Among the 161 deaths, 136 non-survivors were included and 30.1% were younger than 1 year old. Severe pneumonia, respiratory failure and ARDS (31.6%) were the most common primary diagnoses. The most common mode of death was F-CPR …

Cuffed Endotracheal Tubes In Neonates, Nélia Santos Gaspar, Gustavo Rocha, Américo Gonçalves

Journal of Pediatric Intensive Care

Background: Cuffed endotracheal tubes (ETT) are becoming increasingly used in neonates; nevertheless, current data in the literature mostly include infants of over 3000 grams in weight. Objectives: The aim of this study was to compare the use of cuffed and uncuffed ETT in neonates in the neonatal intensive care unit (NICU) of a tertiary children’s hospital, assessing the presence of airway complications. Methods: We performed a single-center retrospective cohort study. Our study included all term neonates receiving cuffed ETT over the period from January 2019 to December 2021. The controls were all neonates receiving an uncuffed ETT over the same …

Slow And Steady: Optimizing Icu Treatment Weans For Children With Chronic Critical Illness, Rachel L. Troch, Alexandra M. Lazzara, Flora N. Yazigi, Carly E. Blatt, Avery W. Zierk, Bethany S. Chalk, Laura M. Prichett, Sofia I. Perazzo, Khodayar Rais-Bahrami, Renee D. Boss

Journal of Pediatric Intensive Care

Objectives: Pediatric chronic critical illness (PCCI) is characterized by prolonged and recurrent hospitalizations, multiorgan conditions, and use of medical technology. Our prior work explored the mismatch between intensive care unit (ICU) acute care models and the chronic needs of patients with PCCI. The objective of this study was to examine whether the number and frequency of treatment weans in ICU care were associated with clinical setbacks and/or length of stay for patients with PCCI. Methods: A retrospective chart review of the electronic medical record for 300 pediatric patients with PCCI was performed at the neonatal ICU (NICU), pediatric ICU (PICU), …

Recent Trends In Incidence And Outcomes For Acute Myocarditis In Children In The United States, Kalpana Singh, Riad Lutfi, John J. Parent, Colin Rogerson, Mouhammad Yabrodi

Journal of Pediatric Intensive Care

Objectives: Lack of defined diagnostic criteria for acute myocarditis makes its diagnosis dependent on clinical suspicion. The objective of this study was to the current trends in demographics, clinical manifestations, treatments, and outcomes in the United States for children hospitalized with acute myocarditis. Methods: This retrospective study was conducted using data collected from the Pediatric Health Information System (PHIS) database for the years 2014-2020. We included patients 21 years or younger with acute myocarditis. The statistical analysis was performed using Chi-squared and continuous variables using Mann-Whitney U-test for continuous data comparisons. Results: We found 1199 patients with acute myocarditis. About …

The Role Of Presepsin As A Biomarker Of Sepsis In Children: A Systemic Review And Meta-Analysis, Daisy Khera, Nisha Toteja, Simranjeet Singh, Siyaram Didel, Kuldeep Singh, Ankita Chugh, Surjit Singh

Journal of Pediatric Intensive Care

Objectives: Biomarkers in sepsis are an arena of avid research as they can facilitate timely diagnosis and help reduce mortality. Presepsin is a promising candidate with good diagnostic performance reported in adult and neonatal studies. However, there is no clear consensus about its utility in the pediatric age group. This study aimed to synthesis scientific evidence regarding the diagnostic and prognostic performance of presepsin in pediatric sepsis. Data Sources: A systematic literature search was conducted in MEDLINE/PubMed, Cochrane Central Register of Clinical Trials, Google Scholar, and Scopus to identify relevant studies reporting the diagnostic and prognostic accuracy of presepsin. Study …

The Caldwell-Gemini Bio-Harmonic Habitat: A Production-Locked, Multi-Modal Wellness System, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract The Caldwell-Gemini Bio-Harmonic Habitat v1.4 is a production-locked, TRL 7 multi-modal wellness environment designed to reduce oxidative stress biomarkers and improve tissue homeostasis. Operating under a CERN-OHL-P v2.0 license, this system integrates three independent modules: a Sleep Module (LIPUS 1.04MHz, Acoustic Gel-Pads, NTC-grid thermal management for HRV +15%), a Transit Module (Bipolar NAI aerosol precipitation for PM2.5 -70% in 60s, Ozone <0.05ppm), and an Environmental Module (Arachne PBM panels for Cortisol +12%). All modules adhere to ISO 60601-1 medical-grade safety standards. The system features Zero-Trust security with AES-256 encryption, HIPAA/GDPR compliance, local AI processing via the #22 AI Monitor, and user-owned "Resonant Keys" for biometric data. User experience is enhanced through 3D-Spacer Fabric comfort and a "Zen Mode" mobile app. The $2,950 prototype BOM is optimized for 2026 industrial supply chains, with a projected retail cost of $1,250 at scale. This v1.4 spec resolves all prior critiques, establishing a clear regulatory path as a General Wellness Device

Gci-132-N Gen-1.2: Omni-Restoration Platform For Non-Invasive Ocular Neuroprotection And Disease Monitoring, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract: GCI-132-N is a non-invasive, wearable ultrasound platform designed for superior ocular neuroprotection and disease monitoring, primarily targeting glaucoma but with applicability to early Parkinson's and Alzheimer's biomarker tracking. This GEN-1.2 dossier presents an industrial blueprint leveraging sonoporation physics, commercial-off-the-shelf (COTS) hardware, and a proprietary Caldwell-Carrier Neuro-Gel with microbubbles. Key features include a 64-element CMUT array for dual-frequency vortex sonoporation, a graphene thermal spreader, PDMS microfluidics for gel refresh, and a self-powered hybrid energy system. A "Caldwell Resonance Signature" customizes ultrasound delivery to individual ocular impedance profiles, enhancing efficiency by 30%. Real-time safety is ensured via triple-redundant interlocks, including pressure, …

Dynamic Packet-Level Ai/Ml Model Instruction Through Extension Headers For Distributed Network Devices, Madhan Sankaranarayanan, Jaganbabu Rajamanickam, Yitong Li, Ganesh Paramasivan, Shivani Suri

Defensive Publications Series

Proposed herein are techniques that facilitate the dynamic execution of Artificial Intelligence/Machine Learning (AI/ML) models at a packet level across distributed nodes, which is distinguished from traditional centralized AI/ML deployment or static configurations. The techniques have the potential to enhance network efficiency, security, and adaptability by enabling real-time, distributed AI/ML inference that is directly activated by network traffic patterns and control signals embedded within packets.

Solid State Form Of Sofpironium Bromide, Msn Laboratories Private Limited, R&D Center, Hyderabad, India; Srinivasan Thirumalai Rajan, Ghojala Venkat Reddy, Uppalanchi Srinivas, And Manda Ananth Reddy.

Defensive Publications Series

The present invention provides a crystalline polymorph of Sofpironium bromide represented by the following structural formula-1 and process for preparation thereof.

Formula-1

Line Crossing Based Unauthorized Movement Detection From Video Footage, Na

Defensive Publications Series

This disclosure describes techniques of line-crossing detection in security camera footage. A security officer or another authorized viewer of the footage draws a line within the field-of-view. The line can be annotated with a direction, such that a person crossing the line in one direction triggers an alarm but crossing it in the opposite direction does not. Person IDs and bounding boxes for each detected person in the time window of interest are retrieved. The coordinates and directionality of drawn lines are retrieved. The bounding boxes are grouped by person ID. Bounding boxes within a group are ordered by timestamp. …

Face-Agnostic Intermittent Loitering Detection In Security Camera Footage, Na

Defensive Publications Series

Security personnel are interested in detecting persons who are loitering in a region captured by a security camera. However, in many scenarios, it is possible that a person walks outside the region captured by a security camera for a period of time before returning to the region. The intermittent presence of the person may not be detected as an instance of loitering. This disclosure describes techniques to detect intermittent loitering in security camera footage. Per the techniques, the period for which a person leaves the screen, if below a certain threshold, is counted towards loitering time. The techniques are face-agnostic, …

Face Agnostic Recognition Of Uniformed Personnel Using Generative Artificial Intelligence, Na

Defensive Publications Series

Footage from security cameras deployed within an organization often includes uniformed employees of the organization, who generally present no security threats. Surfacing the presence of uniformed personnel in security footage can amount to false alarms. This disclosure describes techniques that can identify persons wearing authorized uniforms within security camera footage. Per the techniques, generative artificial intelligence (gen-AI) is used to synthesize images of people wearing various uniforms authorized by the organization, in various poses. Embeddings of the gen-AI images are created and compared with those corresponding to real persons detected in the security camera footage to determine if a detected …

Clustering Person Appearances To Improve Person Recognition, Na

Defensive Publications Series

This disclosure describes techniques that improve the recognition of a person observed in video footage captured by security cameras by leveraging a large number of images of the person obtained from various perspectives from multiple cameras. Images of a person moving through a given space and appearing at various angles and look-directions are obtained and clustered. The cluster of images of a person is subjected to face detection to obtain a gallery of face images for the person. To recognize the person, similarity scores are computed between a reference image of the person and each of the images in the …

Descriptive Search Of Security Camera Footage Via Generative Artificial Intelligence, Na

Defensive Publications Series

While security camera footage can be searched by date/time ranges, it is not possible to search footage using descriptive text phrases. Consequently, investigations of security camera footage are laborious and time consuming. This disclosure describes techniques that enable security operators to search for individuals of interest in security camera footage with descriptive text queries in an efficient, privacy-sensitive manner. Per the techniques, images of individuals captured on security camera footage are optionally modified to blur facial features. After the blurring, embeddings are obtained for different individual images captured in the footage, where similar individuals cluster together in the embedding space. …