Digital Commons Network^™

Moving Forward While Swaying Left And Right: How To Govern National Innovation Systems-Catalysed Innovation Ecosystems?, Jiang Yu

Double Helix Methodology

There is a burgeoning literature arguing that addressing grand challenges, such as de-globalization, requires a set of complementary actors to build innovation ecosystems (IE), which are also strategically integrated into the national innovation system (NIS). We conceptualize this specific systemic phenomenon as a new type of IE—NIS-catalysed IE—whose sustainable growth is said to be constantly hindered by dependent yet opposing tensions. The current literature provides fruitful insights into governing paradoxical tensions; however, some taken-for-granted theoretical assumptions within it are problematic when examining the relationship between salient paradoxes embodied in NIS-catalysed IE and effective governance mechanisms. Drawing on a single longitudinal …

How Does High-Tech Entrepreneurship Affect Incumbent Firm Innovation In Regional Innovation Ecosystems?, Beibei Hu

Double Helix Methodology

High-tech entrepreneurship plays a central role in shaping regional innovation ecosystems, yet the mechanisms through which it affects innovation in incumbent firms remain underexplored. Using firm-level data from the Zhongguancun Science Park (2005–2015), this study investigates the impact of high-tech entrepreneurship on incumbent firms’ innovation. The results reveal that high-tech entrepreneurship significantly enhances innovation among incumbent firms, primarily through R&D investment and human capital. Moreover, this effect is stronger in the electronic information industry and during the development stage. Overall, the study highlights the role of high-tech entrepreneurship in driving the evolution of regional innovation ecosystems. © The Author(s) 2026. …

“Safe Haven" Or “Risk Source" ? The Time-Varying Impact Of Geopolitical Risk On China's Short-Term Capital Flows, Yu Song

Double Helix Methodology

This paper examines the dynamic impact of geopolitical risk on short-term capital flows using a time-varying parameter vector autoregression (TVP-VAR) model and analyzes the transmission mechanism through interest rate differentials and exchange rate expectations. The findings indicate that geopolitical risk is a significant driver of short-term capital flows in China, with increased geopolitical risk leading to short-term cross-border capital outflows. Impulse response analysis across different time points indicates that financial opening-up policies affect short-term capital flows, yet gradual financial opening-up has not significantly amplified the impact of geopolitical risk. Under the influence of geopolitical risk, interest rate differentials and exchange …

Pseudomonas Aeruginosa: A Rare Cause Of Necrotizing Fasciitis, Carrine S. Kogulan, Oluwafemi Ajibola

Student Publications

Necrotizing fasciitis (NF) is a rare but life-threatening soft tissue infection characterized by rapid progression, systemic toxicity, and high mortality. While Group A Streptococcus is the most common pathogen, Pseudomonas aeruginosa is an uncommon cause, typically reported in immunocompromised patients.

We present the case of a 77-year-old male with chronic lymphocytic leukemia (CLL), chronic kidney disease, and other comorbidities who initially presented to an outside facility with three days of fever and left lower extremity pain. He was admitted with presumed cellulitis, and blood cultures grew Pseudomonas aeruginosa. Despite appropriate antibiotic therapy with vancomycin and ceftriaxone, the patient developed …

Modulation Of Pulpal Mmp-8 And Vegf-Alpha By Bioactive Calcium Silicate And Blood Cockle Shell Extract Combination In Rats, Angelia Conny Nidiaty, Noor Hikmah, Kezia Rachellea Mustakim, Wahyuni Suci Dwiandhany, Hafsah Katu, Juni Jekti Nugroho

International Arab Journal of Dentistry

Objectives: This study evaluated MMP-8 and VEGF-Alpha expression in rat dental pulp inflammation after application of bioactive calcium silicate combined with blood cockle shell extract.

Methods: Forty mandibular incisors were randomly assigned to four groups: 100% bioactive calcium silicate (control) and three treatment groups containing 25%, 50%, or 75% shell extract with the remainder calcium silicate. Direct pulp capping was performed, and samples were collected on days 1, 3, 7, and 14.

Results: Immunohistochemistry and one-way ANOVA revealed significant differences in MMP-8 expression on days 1 and 3, and VEGF-Alpha expression across all time points (p < 0.05). The 75% shell extract group showed the lowest MMP-8 and highest VEGF-Alpha expression.

Conclusions: These findings suggest …

Editor’S Introduction, Michael D. Pante

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Bifurcation Exploration Of Ion Acoustic Solitons Formation Of A Nonlinear Beta Fractional Kadomtsev-Petviashvili Burger Model In Plasma State, Mst. Razia Pervin, Alrazi Abdeljabbar, Fahad Sameer Alshammari, Mst. Shekha Khatun, Harun Or-Roshid

Mathematical Modelling and Numerical Simulation with Applications

This research presents an extensive investigation of Ion acoustic soliton dynamics governed by a Beta-fractional Kadomtsev-Petviashvili-Burgurs (KPB) model. By engaging the planar dynamical system scheme in aggregation with the extended $(\phi, \psi)$ expansion, Kudryashov expansion, and the NMKM analytic schemes, we create a broad class of exact nonlinear pattern wave solutions. The local stability edifice of the fractional plasma model is explored through bifurcation theory, enabling the far-reaching classification of all admissible phase diagrams. Conforming Ion acoustic wave structures allied with every detour alignment are systematically assembled. Owing to the fractional and dissipative appearances of the model, an all-embracing assortment …

Employing Effective Solution Methods For Caputo-Based Sequential Fractional Models, Eman A. A. Ziada, Mohamed F. Abouelenein, Hijaz Ahmad, Monica Botros

Mathematical Modelling and Numerical Simulation with Applications

This paper investigates a class of nonlinear sequential singular fractional differential equations (FDEs) involving Caputo derivatives. This type of equation has several key advantages that enhance its value, such as capturing memory and hereditary effects. Viscoelastic materials and anomalous diffusion, as well as biological systems, can take advantage of this feature. In addition, fractional derivatives possess a sequential structure that enables the implementation of multiscale processes and hierarchical memory responses. Moreover, it provides an effective and flexible framework for solving differential equations compared to classical differential equations. It can therefore be used to model complex systems in physics, biology, and …

Numerical Simulations And Hyers-Ulam Stability Of A Novel Nonlocal Anthropogenic Cutaneous Leishmaniasis Mathematical Model, Khalid Fanoukh Al Oweidi, Zakirullah -, Kamal Shah, Thabet Abdeljawad

Mathematical Modelling and Numerical Simulation with Applications

In this work, the fractal-fractional Atangana-Baleanu derivative with the Mittag-Leffler kernel is employed to capture the memory and hereditary effects inherent to anthropogenic cutaneous leishmaniasis transmission dynamics. The Banach fixed-point theorem and contraction mapping principle are used to prove the existence and uniqueness of solutions, while Hyers-Ulam stability of the system is analyzed to demonstrate the robustness of solutions with respect to small perturbations. Using a nonlinear least-squares approach, model parameters and fractional order are estimated using epidemiological data from the World Health Organization. The basic reproduction number $R_0 = 0.53$ indicates that the disease is under control after adding …

Markov-Modulated Queueing Network For Mobile Traffic Aggregation With Threshold-Controlled Buffers, Anton A. Esin, Elmira Yu. Kalimulina

Mathematical Modelling and Numerical Simulation with Applications

We study the problem of data transmission from mobile platforms operating in high-speed transit between cellular base stations, under conditions of unstable and intermittent connectivity. Conventional queueing and connectivity models often fail to capture the combined effects of rapidly changing signal conditions, finite buffer capacity, and dynamic topology. We aim to develop a tractable yet expressive model that integrates stochastic link availability, queue dynamics, and buffer control. We propose a mathematical framework based on queues whose service intensities are modulated by a continuous-time Markov chain (CTMC) representing signal conditions along a high-speed trajectory. The core subsystem is a two-stage (aggregation …

Exact Soliton Solutions Of The Nonlinear Time-Fractional Schrödinger Equation Via Atangana–Baleanu And M-Truncated Operators, Bahadır Kopçasiz, Fatma Nur Kaya Sağlam, Mehmet Şenol

Mathematical Modelling and Numerical Simulation with Applications

The main objective of this work is to obtain exact soliton solutions for a nonlinear time-fractional equation model describing wave profiles arising in various physical systems. To derive different wave structures associated with the considered model, two analytical techniques are employed: the extended G'\G^2-expansion method and the modified auxiliary equation (MAE) approach. A wave transformation is applied to reduce the nonlinear time-fractional equation to a nonlinear ordinary differential equation (NLODE) by means of the M-truncated and Atangana-Baleanu (AB) fractional operators. Several classes of solutions, including exponential, hyperbolic, and trigonometric wave forms, are obtained. Over and above the analytical results, graphical …

Dynamical Analysis And Optimal Control Of The Mpox Transmission Model With Stratified Susceptibility, Tuhfatul Janan, Fatmawati Fatmawati, Cicik Alfiniyah, Santi Martini, Dipo Aldila, Agus Hasan

Mathematical Modelling and Numerical Simulation with Applications

This study develops a mathematical model of Mpox transmission that combines stratified susceptibility (low-risk and high-risk groups) with vaccinated and asymptomatically infected compartments. The analysis of the model begins with examining the well-posedness, boundedness, and nonnegativity conditions for the solutions. The local stabilities of the equilibria are examined through the Jacobian matrix and phase plane analysis, while the global stabilities are provided through Lyapunov functions. The estimated parameters are verified using epidemiological data on Mpox cases in the United States, with an MAPE of 2.20% and R_0 > 1, indicating that Mpox remains endemic. Sensitivity analysis indicates that the contact rate …

Mark-Brian Kline V. Alien Property Custodian Representative

2026 Decisions

USDC for the District of New Jersey

Vermonters See No Role For Religion In Public Life, Nearly Half Identify As Non-Religious 3/31/2026, Unh Survey Center

All UNH Survey Center Polls

Two-thirds of Vermont adults say they never attend religious services, despite many regularly attending in their childhood, and nearly half of the population identify as agnostic, atheist, or religiously unaffiliated, while less than one-fifth each identify as Catholic or Protestant. Overall, a majority say that religion is not very or not at all important to their lives. State residents are split on whether religion has a positive or negative effect on society but most feel that religion should play no role in public affairs and that prayer is public schools is inappropriate. Notwithstanding these opinions, about half of Vermonters personally …

Neutrosophic Sets In Neural Networks: Theory, Applications, And Challenges, Vladimir Simic, Dragan Pamucar, Hafiz Muhammad Athar Farid

Neutrosophic Systems with Applications

The integration of neutrosophic sets into neural networks presents a novel approach to handling uncertainty, indeterminacy, and falsity in data. Traditional neural networks typically operate under the assumption of precise and complete data, but real-world applications often involve noisy, incomplete, or ambiguous information. Neutrosophic sets extend fuzzy logic by incorporating three components: truth, indeterminacy, and falsity, allowing for a more nuanced representation of uncertain data. This paper explores the theoretical foundations of neutrosophic sets and their integration with neural networks, highlighting the challenges in computational complexity, training, and optimization. The paper also discusses the potential applications of neutrosophic neural networks …

Neutrosophic Probability With Dynamic Temporal Uncertainty (Nptu), Bhimraj Basumatary, Ashoke Kumar Brahma

Neutrosophic Systems with Applications

This paper introduces Neutrosophic Probability with Dynamic Temporal Uncertainty (NPTU), an extension of classical neutrosophic probability that incorporates the dimension of time. In classical neutrosophic probability, the degrees of truth, indeterminacy, and falsity are considered static. However, real-world uncertainties evolve, and their degrees change as new information becomes available. NPTU models these uncertainties dynamically, allowing for more accurate decision-making in time-varying environments. The paper explores key mathematical properties of NPTU, including entropy, distance measures, similarity measures, and Kullback-Leibler (KL) divergence, to quantify and compare temporal uncertainty states. The proposed framework is demonstrated through a case study on stock price prediction, …

Emergent Operator Logic: A Foundational Framework For Dynamic Reasoning And Generative Intelligence, Mona Gharib, Abduallah Gamal, Muhammad Nawaz, Basma Nasir

Neutrosophic Systems with Applications

This paper introduces Emergent Operator Logic (EOL), a framework that treats propositions as continuous operators $F_p:X \rightarrow X$ on a complete metric state space $( X,d )$ and evaluates truth after action via a continuous valuation $V:X \rightarrow [ 0,1 ]$. Logical composition is realized by three operator-level connectives: sequential $p \circ q$(causal order), parallel $p\parallel q$(1-Lipschitz cooperative blend), and the emergent synthesis $E( p,q ) = \frac12( F_p \circ F_q + F_q \circ F_p )$, which symmetrizes non-commuting actions. We provide a Hilbert-style proof system (sound), an algebraic semantics via E-algebras, and show that the category of E-algebras is …

Double-Valued Complex Neutrosophic Graphs, Suriyakumar G, V. J. Sudhakar, Takaaki Fujita

Neutrosophic Systems with Applications

This paper introduces a novel graph-theoretic framework, called the double-valued complex neutrosophic graph, as an extension of double-valued neutrosophic set theory. Within this framework, we investigate several important classes of such graphs, including self-complementary, strong, and full double-valued complex neutrosophic graphs, and establish a number of their fundamental properties. To clarify the proposed concepts and demonstrate their structural behavior, several relevant illustrative examples are also provided.

Staff Education To Improve Mental Health Staff Knowledge On Mobile Health Applications For Medication Adherence, Chipasha Chingwengwezi

Walden Dissertations and Doctoral Studies

Despite rising evidence supporting the efficacy of mobile health (mHealth) applications to enhance medication adherence among individuals with mental health conditions, there is little utilization of these applications within mental health facilities. This project aimed to address the issue of implementing an interactive education program to enhance the knowledge of mental health staff and skills in the application of mHealth apps to enhance medication adherence. The main objective of this project was to fill the gap between conducting research and implementing its outcomes by providing staff with the knowledge and skills to incorporate mHealth applications into their daily practice. The …

Nursing Students’ Attitudes About Correcting Health Misinformation On Social Media, Heather Ann Hill

Walden Dissertations and Doctoral Studies

Health misinformation on social media is a global public health concern. Research has shown that health misinformation causes significant harm in communities, especially for vulnerable populations with existing health disparities. Nurses have been urged to play a more significant role in combating health misinformation. Existing research has shown that nurses are hesitant to correct health misinformation on social media, but attitudes among current nursing students have not been examined. The purpose of this qualitative descriptive study was to explore nursing students' attitudes about correcting health misinformation on social media. Guided by Ajzen’s theory of planned behavior and Paterson and Zderad’s …

Alignment Of Projects With Business Strategy, Lyndon Leathan Martin

Walden Dissertations and Doctoral Studies

Some organizations lack strategies to ensure that project outcomes are aligned with organizational objectives. Business leaders are concerned when project outcomes are misaligned with organizational objectives, as this can lead to decreased profitability and a loss of competitive advantage. Grounded in Porter’s Five Forces model, the purpose of this qualitative, pragmatic inquiry was to explore the strategies business leaders use to ensure project outcomes are profitable and aligned with organizational objectives. The participants were six executive leaders of real estate and development companies in the Caribbean, purposefully selected because their organizations had successfully fulfilled organizational objectives through project outcomes. Data …

A Hybrid Multi-Criteria Decision-Making Approach For Sustainable Forest Fire Monitoring Using Unmanned Aerial Vehicles, Mohamed Eassa, Ahmed Abdelhafeez, Ahmad M. Nagm

Neutrosophic Systems with Applications

Unmanned aerial vehicles (UAVs) have become an effective tool for forest fire monitoring. This study evaluates UAVs for forest fire management, addressing the challenges posed by ambiguous and uncertain factors. Single-valued neutrosophic sets (SVNSs) are employed to model complex uncertainties, as they incorporate three distinct membership values: false, true, and indeterminate. The evaluation of UAVs is a multifaceted task due to the variety of factors involved. To address this complexity, multi-criteria decision-making (MCDM) methods are used. Specifically, the Analytic Hierarchy Process (AHP) and the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) are integrated with SVNS to …

Taiwan Healthcare Professionals' Perception, Attitudes, And Experience About Balint Groups: A Two-Stage Pilot Study, Ing-Tiat Tiunn, Chung-Han Ho

Journal of Medical Education

Background: Balint groups have been widely implemented to support medical training in many countries. However, no empirical study has yet been conducted in Taiwan to evaluate their effectiveness.

Methods: An introductory presentation on Balint groups was held at a medical center in southern Taiwan, followed by a survey assessing attendees' perceptions and attitudes toward Balint work. Subsequently, a six-session Balint group was offered to healthcare professionals who volunteered to participate. All participants completed the 25-item Resilience Scale before and after the intervention. Thematic analysis was employed to analyze qualitative data.

Results: A total of 44 healthcare professionals attended …

From Time-Based To Competency-Based: A Decade-Long Transformation Of Medical Radiation Technologist Education In Taiwan And Its Implications For System-Level Cbme Reform, Yao-Ting Lu, Shu-Yu Wen, Chiao-Ling Tsai, Cheng-Heng Liu, Wen-Tao Huang, Chia-Hung Chen, Chih-Wei Yang

Journal of Medical Education

Competency-based medical education (CBME) has reshaped physician training, yet system-level implementation in allied health professions is rarely described. In this Perspective, we examine Taiwan's decade-long national reform of medical radiation technologist (MRT) education led by the Taiwan Association of Medical Radiation Technologists (TAMRT) and distill lessons for system-level CBME. Beginning in 2012, TAMRT adapted the Accreditation Council for Graduate Medical Education (ACGME) core competencies and introduced workplace-based assessments across diagnostic radiography, radiation therapy, and nuclear medicine. Early national accreditation cycles revealed persistent variability in assessment quality and highlighted the limitations of time-based advancement. TAMRT therefore shifted from adding isolated tools …

Student Achievements Showcase Impact Of (603) Challenge Gifts, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Regulation Of Zygotic Genome Activation By The Nucleocytoplasmic Ratio, Lily Acker, Hui Chen

Faculty Publications

During early development, embryos undergo the maternal-to-zygotic transition (MZT), when control of development shifts from maternal factors to the newly activated zygotic genome. Decades of studies in various model organisms suggest that the nucleocytoplasmic (N/C) ratio is a key regulator of zygotic genome activation (ZGA), though this relationship is more nuanced in some organisms than others. Changing the nuclear content, nucleus size or cell size has been shown to shift the timing of ZGA. Mechanistically, the N/C ratio is linked to fundamental cellular processes that regulate genome activities, including nuclear import, repressor titration, activator accumulation, cell cycle lengthening, and chromatin …

Sulfatase Modifying Factors Control The Timing Of Zebrafish Convergence And Extension Morphogenesis, Ailen Soledad Cervino, Amrita Basu, Ryan J Weiss, Gursimran Kaur Bajwa, Rubén Marín-Juez, Sandra L Grimm, Cristian Coarfa, Margot Kossmann Williams

Faculty, Staff and Students Publications

Convergence and extension (C&E) cell movements that elongate the primary embryonic axis are precisely timed during vertebrate gastrulation, but mechanisms controlling their onset remain unknown. Using zebrafish embryonic explants that recapitulate C&E and its timing, we identified sulfatase modifying factor 2 (sumf2) as a candidate trigger gene for C&E onset. sumf2 and its paralog sumf1 encode negative and positive sulfatase regulators, respectively, whose expression levels invert and increase heparan sulfate sulfation during gastrulation. Overexpressing sumf1 or sumf2 causes delayed or precocious C&E, respectively, whereas their loss shifts C&E timing in the opposite direction. We identified Sulf1, a modifier of heparan …

Helminth Coinfections Mitigate Clinical, Parasitological, And Immune Outcomes In Mozambican Children With Malaria, Inocência Cuamba, Rebeca Santano, Berta Grau-Pujol, Marta Vidal, Ruth Aguilar, Anélsio Cossa, Chenjerai Jairoce, Rojelio Mejia, Augusto Nhabomba, Jose Muñoz, Gemma Moncunill, Carlota Dobaño

Faculty, Staff and Students Publications

Background: Clearance of Plasmodium falciparum infection requires a TH1 immune response with production of pro-inflammatory cytokines, IgG1, and IgG3 responses. In contrast, infections with helminths are dominated by TH2/Treg immune responses characterized by production of anti-inflammatory cytokines, IgE, and IgG4, which could potentially interfere with malaria outcomes and immune responses.

Methods: We recruited 441 malaria-symptomatic children aged 2-10 years attending two hospitals in the Manhiça District (Mozambique) and assessed infection by rapid antigen diagnostic test, microscopy, and/or quantitative PCR. Using Luminex, we measured concentrations of 30 cytokines and IgA, IgM, IgE, IgG, and IgG1-4 levels against 12 P. falciparum antigens …

High-Power Dual-Channel Chamber For High-Frequency Magnetic Neuromodulation, Xiaoyang Tian, Hui Wang, Boshuo Wang, Jinshui Zhang, Dong Yan, Jeannette Ingabire, Samantha Coffler, Guillaume Duret, Quoc-Khanh Pham, Gang Bao, Junzhe Wang, Ashok Veeraraghavan, Jacob T Robinson, Stefan M Goetz, Angel V Peterchev

Faculty, Staff and Students Publications

Objective. Several novel methods, including magnetogenetics and magnetoelectric stimulation, use high frequency alternating magnetic fields to precisely manipulate neural activity. To quantify the behavioral effects of such interventions in a freely moving mouse, we developed a dual-channel magnetic chamber, specifically designed for rate-sensitive magnetothermal-genetic stimulation, and adaptable for other uses of alternating magnetic fields.

Approach. Through an optimized coil design, the system allows independent control of two spatially orthogonal uniform magnetic fields delivered at different frequencies within a 10 × 10 × 6 cm3 chamber suitable for mouse studies. The two channels have nominal frequencies of 50 and 550 kHz …

Toxicity, Chemistry, And Public Health Relevance Of Emerging Nicotine Analog Vapes, Pods, And Pouches., Rhea Raghu, Mohana Sengupta, Karen Lin, Felix Effah, Robert M. Strongin, Irfan Rahman

Chemistry Faculty Publications and Presentations

Electronic nicotine delivery system manufacturers, such as Charlie's Holdings Inc., ECBlend, Outlaw, and NicRiver, have recently introduced nicotine analogs, such as 6-methyl nicotine, 6-MN ("Metatine"), and nicotinamide, NA ("Nixamide," "Nixodine," or "Nixotin-free base and salt") in products to circumvent the U.S. FDA's premarket tobacco product application (PMTA) requirements. Marketed as "tobacco-free," "PMTA-exempt," or "FDA-approved," these compounds now appear in oral nicotine pouches and disposable bars/vapes from brands such as Outlaw Dip, Kumi-Six, SBX, Katchmi, and Spree Bar under proprietary labels including "NoNic6," "Metatine," or "NIC-SAFE." These products often mimic the appeal of conventional nicotine delivery systems, with extensive use of …