Digital Commons Network^™

How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu

Children’s Nutrition Research Center Staff Publications

Background: eHealth interventions using active video games (AVGs) offer an alternative method to help children exercise, especially during a pandemic where options are limited. There is limited data on costs associated with developing and implementing such interventions.

Objectives: We quantified the costs of delivering an eHealth RCT intervention among minority children during COVID-19.

Methods: We categorized the total trial cost into five subcategories: intervention material development, advertising and recruitment, intervention delivery, personnel salaries, and COVID-19-related equipment costs.

Results: The total RCT cost was $1,927,807 (Direct: $1,227,903; Indirect: $699,904) with three visits required for each participant. The average cost per participant …

Mathematical Modeling Of Microscale Biology: Ion Pairing, Spatially Varying Permittivity, And Born Energy In Glycosaminoglycan Brushes, William J. Ceely, Marina Chugunova, Ali Nadim, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

Biological macromolecules including nucleic acids, proteins, and glycosaminoglycans are typically anionic and can span domains of up to hundreds of nanometers and even micron length scales. The structures exist in crowded environments that are dominated by multivalent electrostatic interactions that can be modeled using mean-field continuum approaches that represent underlying molecular nanoscale biophysics. We develop such models for glycosaminoglycan brushes using steady state modified Poisson-Boltzmann models that incorporate important ion-specific (Hofmeister) effects. The results quantify how electroneutrality is attained through ion electrophoresis, spatially varying permittivity hydration forces, and ion-specific pairing. Brush-salt interfacial profiles of the electrostatic potential as well as …

A Simple Point-Of-Care Assay Accurately Detects Anti-Spike Antibodies After Sars-Cov-2 Vaccination, Sarah E Greene, Yuefang Huang, Wooseob Kim, Mariel J Liebeskind, Vinay Chandrasekaran, Zhuoming Liu, Parakkal Deepak, Michael A Paley, Daphne Lew, Mary C Nakamura, Jane A O'Hallaran, Rachel M Presti, Sean P J Whelan, William J Buchser, Alfred H J Kim, Gary J Weil, Et Al.

2020-Current year OA Pubs

OBJECTIVE: Lateral flow assays (LFA) are sensitive for detecting antibodies to SARS-CoV-2 proteins within weeks after infection. This study tested samples from immunocompetent adults, and those receiving treatments for chronic inflammatory diseases (CID), before and after mRNA SARS-CoV-2 vaccination.

METHODS: We compared results obtained with the COVIBLOCK Covid-19 LFA to those obtained by anti-spike (S) ELISA.

RESULTS: The LFA detected anti-S antibodies in 29 of 29 (100%) of the immunocompetent and 110 of 126 (87.3%) of the CID participants after vaccination. Semiquantitative LFA scores were statistically significantly lower in samples from immunosuppressed participants, and were significantly correlated with anti-S antibody …

The Use And Challenges Of Spatial Data In Archaeology, Carla Klehm

Anthropology Faculty Publications and Presentations

Spatial data, under the broader umbrella of digital data, is becoming increasingly integral to all stages of archaeological research design and dissemination. As archaeologists lean toward reuse and interoperability, with ethics on their minds, how to treat spatial data is of particular importance. This is because of the complexities involved at every life-cycle stage, from collection to publication, including black box issues that may be taken for granted, and because the size of spatial data can lead to archiving difficulties. Here, the “DIY” momentum of increasingly accessible spatial methods such as photogrammetry and handheld lidar is examined alongside forthcoming changes …

Knockout Of Tsc2 In Nav1.8+ Neurons Predisposes To The Onset Of Normal Weight Obesity, Jennifer M Brazill, David Shin, Kristann Magee, Anurag Majumdar, Ivana R Shen, Valeria Cavalli, Erica L Scheller

2020-Current year OA Pubs

OBJECTIVE: Obesity and nutrient oversupply increase mammalian target of rapamycin (mTOR) signaling in multiple cell types and organs, contributing to the onset of insulin resistance and complications of metabolic disease. However, it remains unclear when and where mTOR activation mediates these effects, limiting options for therapeutic intervention. The objective of this study was to isolate the role of constitutive mTOR activation in Nav1.8-expressing peripheral neurons in the onset of diet-induced obesity, bone loss, and metabolic disease.

METHODS: In humans, loss of function mutations in tuberous sclerosis complex 2 (TSC2) lead to maximal constitutive activation of mTOR. To mirror this in …

Primary Central Nervous System Germ Cell Tumors In Children And Young Adults: A Review Of Controversies In Diagnostic And Treatment Approach, Kee Kiat Yeo, Sumanth Nagabushan, Girish Dhall, Mohamed S Abdelbaki

2020-Current year OA Pubs

Primary central nervous system (CNS) germ cell tumors (GCT) are a rare heterogenous group of cancers, arising most commonly in the second decade of life. Through several clinical trials conducted around the world by various groups, the treatment approach for CNS GCT has advanced substantially with generally improved overall outcomes. In recent years, the goal of clinical trials has been focused on reduction of the radiotherapy burden and minimization of long-term toxicity. This review summarizes the current diagnostic and treatment regimens for CNS GCT, examines the controversies associated with these approaches, gaps in contemporary knowledge, and underscores the challenges we …

Machine Learning Approximations To Predict Epigenetic Age Acceleration In Stroke Patients, Isabel Fernández-Pérez, Joan Jiménez-Balado, Uxue Lazcano, Eva Giralt-Steinhauer, Lucía Rey Álvarez, Elisa Cuadrado-Godia, Ana Rodríguez-Campello, Adrià Macias-Gómez, Antoni Suárez-Pérez, Anna Revert-Barberá, Isabel Estragués-Gázquez, Carolina Soriano-Tarraga, Jaume Roquer, Angel Ois, Jordi Jiménez-Conde

2020-Current year OA Pubs

Age acceleration (Age-A) is a useful tool that is able to predict a broad range of health outcomes. It is necessary to determine DNA methylation levels to estimate it, and it is known that Age-A is influenced by environmental, lifestyle, and vascular risk factors (VRF). The aim of this study is to estimate the contribution of these easily measurable factors to Age-A in patients with cerebrovascular disease (CVD), using different machine learning (ML) approximations, and try to find a more accessible model able to predict Age-A. We studied a CVD cohort of 952 patients with information about VRF, lifestyle habits, …

Stressors, Coping Strategies, And Achievement During Teaching Practicum In A Nigerian Public University, Mensah Prince Osiesi, Udukhomose Suleiman Omokhabi, Sunday Ade Adeniran, Oluwayemisi Damilola Akomolafe, Oluwatoyin Tolu Obateru, Chigozie Celestina Oke, Adenike Lucia Aruleba

Higher Learning Research Communications

Objectives: This study assessed pre-service teacher stressors, coping strategies, and achievement during teaching practicum in a Nigerian public university.

Method: The study adopted the quantitative case study approach. The population consisted of all 300-level students in the faculty of education in the university who had completed their teaching practicum for the first semester of the 2020–2021 academic session. The quota sampling technique was used in selecting a sample of 130 pre-service teachers. We analysed data using multiple regression.

Results: Findings revealed the stressors and coping strategies, controlling for gender, did not significantly predict achievement in the teaching practicum. Several coping …

The Tetraspanin Transmembrane Protein Cd53 Mediates Dyslipidemia And Integrates Inflammatory And Metabolic Signaling In Hepatocytes, Cassandra B Higgins, Joshua A Adams, Matthew H Ward, Zev J Greenberg, Małgorzata Milewska, Jiameng Sun, Yiming Zhang, Luana Chiquetto Paracatu, Qian Dong, Samuel Ballentine, Weikai Li, Ilona Wandzik, Laura G Schuettpelz, Brian J Debosch

2020-Current year OA Pubs

Tetraspanins are transmembrane signaling and proinflammatory proteins. Prior work demonstrates that the tetraspanin, CD53/TSPAN25/MOX44, mediates B-cell development and lymphocyte migration to lymph nodes and is implicated in various inflammatory diseases. However, CD53 is also expressed in highly metabolic tissues, including adipose and liver; yet its function outside the lymphoid compartment is not defined. Here, we show that CD53 demarcates the nutritional and inflammatory status of hepatocytes. High-fat exposure and inflammatory stimuli induced CD53 in vivo in liver and isolated primary hepatocytes. In contrast, restricting hepatocyte glucose flux through hepatocyte glucose transporter 8 deletion or through trehalose treatment blocked CD53 induction …

Crypto Assets And The Problem Of Tax Classifications, Eric D. Chason

Faculty Publications

To date, Internal Revenue Service (I.R.S.) guidance on cryptocurrencies has been thin. When the I.R.S. has issued guidance, it occasionally mishandles the technical details (such as confusing air drops and hard forks). More personnel (and personnel with greater technical expertise) would allow the I.R.S. to keep pace with the explosive growth of cryptocurrency. Nevertheless, the I.R.S. could better leverage its existing resources by focusing on select issues and seeking enabling legislation from Congress. Specifically, the I.R.S. should focus on crypto issues occurring on a system-wide basis and not requiring taxpayer-specific considerations.

For example, determining whether Bitcoin is a “security” under …

Understanding And Improving Older People’S Well-Being Through Social Prescribing Involving The Cultural Sector: Interviews From A Realist Evaluation, Jordan Gorenberg, Stephanie Tierney, Geoff Wong, Amadea Turk, Sebastien Libert, Caroline Potter, Kathryn Eccles, Shona Forster, Kerryn Husk, Helen J. Chatterjee, Emma Webster, Beth Mcdougall, Harriet Warburton, Lucy Shaw, Kamal R. Mahtani

Peninsula Medical School

Social prescribing is a non-clinical approach to addressing social, environmental, and economic factors affecting how people feel physical and/or emotionally. It involves connecting people to ?community assets? (e.g., local groups, organizations, and charities) that can contribute to positive well-being. We sought to explain in what ways, for whom, and why the cultural sector can support social prescribing with older people. We conducted semi-structured interviews with 28 older people (aged 60+) and 25 cultural sector staff. The following nine concepts, developed from interview data, progressed the understanding of tailoring cultural offers, which came from our previous realist review?immersion, buddying, café culture, …

Using Digital Technologies To Facilitate Social Inclusion During The Covid‐19 Pandemic: Experiences Of Co‐Resident And Non‐Co‐Resident Family Carers Of People With Dementia From Determind‐C19, B Hicks, Determind Team

Peninsula Medical School

Background The COVID-19 pandemic triggered rapid and unprecedented changes in the use of digital technologies to support people's social inclusion. We examined whether and how co-resident and non-co-resident family carers of people with dementia engaged with digital technologies during this period. Methods Throughout November 2020-February 2021, we interviewed 42 family carers of people with dementia from our DETERMIND-C19 cohort. Preliminary analysis was conducted through Framework analysis, followed by an inductive thematic analysis. Findings Digital technologies served as a Facilitator for social inclusion by enabling carers to counter the effects of the differing restrictions imposed on them so they could remain …

Overexpression Of Both Human Sodium Iodide Symporter (Nis) And Brg1-Bromodomain Synergistically Enhances Radioiodine Sensitivity By Stabilizing P53 Through Npm1 Expression, J Na, C-H Lee, J-K Chung, H Youn

Peninsula Medical School

Improved therapeutic strategies are required to minimize side effects associated with radioiodine gene therapy to avoid unnecessary damage to normal cells and radiation-induced secondary malignancies. We previously reported that codon-optimized sodium iodide symporter (oNIS) enhances absorption of I-131 and that the brahma-associated gene 1 bromodomain (BRG1-BRD) causes inefficient DNA damage repair after high-energy X-ray therapy. To increase the therapeutic effect without applying excessive radiation, we considered the combination of oNIS and BRG1-BRD as gene therapy for the most effective radioiodine treatment. The antitumor effect of I-131 with oNIS or oNIS+BRD expression was examined by tumor xenograft models along with functional …

Multiple Sclerosis And Neuromyelitis Optica Spectrum Disorder: Onset Following Acute Covid-19 Infection, A Case Series, Mirla Avila, Yuanyuan Tan, Roberto Hernandez, Hafsa Zuberi, Victor M Rivera

Faculty, Staff and Students Publications

BACKGROUND AND OBJECTIVES: Acute COVID-19 infection has been associated with neurological involvement. We report a case series of newly diagnosed patients with multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) developed in a short period of time after acute COVID-19 infection.

METHODS: New MS patients developing initial symptoms shortly after an acute COVID-19 infection were diagnosed based on the 2017 McDonald Criteria [Garcia-Ramos et al. in Cells, 2021]. The patients diagnosed with NMOSD met the 2015 International Panel criteria for the diagnosis of NMOSD (IPDN) [Thompson et al. in Lancet Neurol 17:162-173, 2018].

RESULTS FROM THE MS PATIENT GROUP: …

Final Findings From The Control Trial: Strategies To Reduce The Incidence And Severity Of Neratinib-Associated Diarrhea In Patients With Her2-Positive Early-Stage Breast Cancer, Arlene Chan, Ron Bose, Et Al.

2020-Current year OA Pubs

BACKGROUND: Neratinib is an irreversible pan-HER tyrosine kinase inhibitor approved for HER2-positive early-stage and metastatic breast cancer. Diarrhea is the most frequent side effect and the most common reason for early discontinuation. The phase II CONTROL trial investigated antidiarrheal prophylaxis or neratinib dose escalation (DE) for prevention of diarrhea. We present complete study results including final data for two DE strategies.

METHODS: Patients who completed trastuzumab-based adjuvant therapy received neratinib 240 mg/day for 1 year. Early cohorts investigated mandatory prophylaxis with loperamide, then additional budesonide or colestipol. Final cohorts assessed neratinib DE over the first 2 (DE1) or 4 weeks …

Sex-Specific Hypnotic Effects Of The Neuroactive Steroid (3Β,5Β,17Β)-3-Hydroxyandrostane-17-Carbonitrile Are Mediated By Peripheral Metabolism Into An Active Hypnotic Steroid, Francesca M Manzella, Omar H Cabrera, Davis Wilkey, Brier Fine-Raquet, Jelena Klawitter, Kathiresan Krishnan, Douglas F Covey, Vesna Jevtovic-Todorovic, Slobodan M Todorovic

2020-Current year OA Pubs

BACKGROUND: The novel synthetic neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile (3β-OH) blocks T-type calcium channels but does not directly modulate neuronal γ-aminobutyric acid type A (GABA

METHODS: We used a combination of behavioural loss of righting reflex, neuroendocrine, pharmacokinetic, in vitro patch-clamp electrophysiology, and in vivo electrophysiological approaches in wild-type mice and in genetic knockouts of the Ca

RESULTS: Adult male mice were less sensitive to the hypnotic effects of 3β-OH compared with female mice, and these differences appeared during development. Adult males had higher 3β-OH brain concentrations despite being less sensitive to its hypnotic effects. Females metabolised 3β-OH into the active GABA …

Relationship Between Electrode Position And Temporal Modulation Sensitivity In Cochlear Implant Users: Are Close Electrodes Always Better?, Ning Zhou, Xuyang Shi, Omkar Dixit, Jill B Firszt, Timothy A Holden

2020-Current year OA Pubs

Temporal modulation sensitivity has been studied extensively for cochlear implant (CI) users due to its strong correlation to speech recognition outcomes. Previous studies reported that temporal modulation detection thresholds (MDTs) vary across the tonotopic axis and attributed this variation to patchy neural survival. However, correlates of neural health identified in animal models depend on electrode position in humans. Nonetheless, the relationship between MDT and electrode location has not been explored. We tested 13 ears for the effect of distance on modulation sensitivity, specifically targeting the question of whether electrodes closer to the modiolus are universally beneficial. Participants in this study …

Dexamethasone To Prevent Everolimus-Induced Stomatitis (Alliance Mist Trial: A221701), Kathryn J Ruddy, David Zahrieh, Jun He, Blake Waechter, Julianne L Holleran, Lionel D Lewis, Selina Chow, Jan Beumer, Matthias Weiss, Nikolaos Trikalinos, Bryan Faller, Maryam Lustberg, Hope S Rugo, Charles Loprinzi

2020-Current year OA Pubs

mTOR inhibitors such as everolimus may cause oral stomatitis, often a dose-limiting toxicity. Prior clinical research has suggested that a dexamethasone mouth rinse might help prevent and/or treat this. Alliance A221701 was a randomized phase III trial of patients initiating 10 mg daily oral everolimus that compared dexamethasone mouthwash taken preventively (initial dexamethasone group) versus therapeutically (initial placebo group) to assess two coprimary endpoints: the incidence of mTOR inhibitor-associated stomatitis (mIAS), and the area under the curve (AUC) of mIAS-associated pain over an 8-week treatment period. A Fisher's exact test was used to compare the incidences while a Wilcoxon rank-sum …

Smart Bidirectional Charging For Frequency Support Of A Low-Inertia Vehicle-To-Grid System In Presence Of Energy Storage Systems, Majid Mehrasa, Hossein Salehfar, Daisy Flora Selvaraj, Sina Ibne Ahmed

EERC Publications, Papers, & Presentations

This paper focuses on the challenge to develop coordination between an electric vehicle (EV) charger, energy storage system (ESS), and smart charging/discharging strategy in a low-inertia grid-connected vehicle-to-grid system. Two smart bidirectional charging strategies are proposed to control EV and ESS for minimizing the frequency error by considering the EV constraints.

Robust Control Strategy For A High-Power Off-Board Ev Charger Connected To Grid-Tied Critical Loads, Majid Mehrasa, Daisy Flora Selvaraj, Hossein Salehfar

EERC Publications, Papers, & Presentations

One of the main duties of electric vehicles (EVs) is to provide smooth and robust power flow for the grid-tied loads in the vehicle-to-grid application. To this end, this paper proposes a comprehensive control system for a high-power off-board EV charger to appropriately generate/consume power when sudden reference power alteration and disturbance on the DC-link voltage measurement exist.

Would You Like Fries With That? Investigating Fast-Food Outlet Availability Near Schools In Perth, Western Australia, Gina S. A. Trapp, Paula Hooper, Wesley Billingham, Lukar Thornton, Ainslie Sartori, Kelly Kennington, Amanda Devine, Stephanie Godrich, Ros Sambell, Justine Howard, Alexia Bivoltsis

Research outputs 2022 to 2026

Issue addressed: Locating fast-food outlets near schools is a potential public health risk to schoolchildren, given the easy access and repeated exposure to energy-dense, nutrient-poor foods they provide. Fast-food outlet availability near schools has not been previously investigated in Perth, Western Australia. This study aimed to quantify fast-food outlet availability near Perth schools and determine whether differences in area-level disadvantage and school type exist. Methods: Fast-food outlet locations were sourced from Perth Local Governments in 2018/2019. All Perth Primary (n = 454), Secondary (n = 107) and K-12 (n = 94) schools were assigned an area-level disadvantage decile ranking based …

Australian Consumers’ Attitudes Towards Sustainable Diet Practices Regarding Food Waste, Food Processing, And The Health Aspects Of Diet: A Cross Sectional Survey, Janelle D. Healy, Satvinder S. Dhaliwal, Christina M. Pollard, Piyush Sharma, Clare Whitton, Lauren C. Blekkenhorst, Carol J. Boushey, Jane A. Scott, Deborah A. Kerr

Research outputs 2022 to 2026

Environmentally sustainable diets are increasingly aspired to in food-based dietary guidelines across the world. However, little is known about consumer attitudes toward these diets when making food decisions. This study aimed to identify the demographic characteristics of Australian adults based on the level of attention they paid to the healthfulness of their diet, their consideration of the level of food processing, and their concern about household food waste and sustainable packaging disposal. Adults aged from 18 to over 75 years (n = 540) were surveyed online. Thirty-seven percent were concerned about sustainable food waste, 28 % considered the level of …

Deep Feature Meta-Learners Ensemble Models For Covid-19 Ct Scan Classification, Jibin B. Thomas, K. V. Shihabudheen, Sheik Mohammed Sulthan, Adel Al-Jumaily

Research outputs 2022 to 2026

The infectious nature of the COVID-19 virus demands rapid detection to quarantine the infected to isolate the spread or provide the necessary treatment if required. Analysis of COVID-19-infected chest Computed Tomography Scans (CT scans) have been shown to be successful in detecting the disease, making them essential in radiology assessment and screening of infected patients. Single-model Deep CNN models have been used to extract complex information pertaining to the CT scan images, allowing for in-depth analysis and thereby aiding in the diagnosis of the infection by automatically classifying the chest CT scan images as infected or non-infected. The feature maps …

Digital Twin Applications In 3d Concrete Printing, Yuxin Wang, Farhad Aslani, Arcady Dyskin, Elena Pasternak

Research outputs 2022 to 2026

The benefits of 3D concrete printing (3DCP) include reducing construction time and costs, providing design freedom, and being environmentally friendly. This technology is expected to be effective in addressing the global house shortage. This review highlights the main 3DCP applications and four critical challenges. It is proposed to combine 3D concrete printing with Digital Twin (DT) technology to meet the challenges the 3DCP faces and improve quality and sustainability. This paper provides a critical review of research into the application of DT technology in 3DCP, categorize the applications and directions proposed according to different lifecycles, and explore the possibility of …

Epigenetic Regulation Of Corneal Epithelial Differentiation By Tet2, Yuzuru Sasamoto, Siyuan Wu, Catherine A. A. Lee, Jason Y. Jiang, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank

Research outputs 2022 to 2026

Epigenetic DNA modification by 5-hydroxymethylcytosine (5hmC), generated by the Ten-eleven translocation (TET) dioxygenases, regulates diverse biological functions in many organ tissues, including the mammalian eye. For example, 5hmC has been shown to be involved in epigenetic regulation of retinal gene expression. However, a functional role of 5hmC in corneal differentiation has not been investigated to date. Here, we examined 5hmC and TET function in the human cornea. We found 5hmC highly expressed in MUC16-positive terminally differentiated cells that also co-expressed the 5hmC-generating enzyme TET2. TET2 knockdown (KD) in cultured corneal epithelial cells led to significant reductions of 5hmC peak distributions …

Exploring Sociodemographic Correlates Of Suicide Stigma In Australia: Baseline Cross-Sectional Survey Findings From The Life-Span Suicide Prevention Trial Studies, Lisa N. Sharwood, Alison L. Calear, Philip J. Batterham, Michelle Torok, Lauren Mcgillivray, Demee Rheinberger, Stephanie Zeritis, Tuguy Esgin, Fiona Shand

Research outputs 2022 to 2026

The risk of suicidal behaviour in Australia varies by age, sex, sexual preference and Indigenous status. Suicide stigma is known to affect suicide rates and help-seeking for suicidal crises. The aim of this study was to investigate the sociodemographic correlates of suicide stigma to assist in prevention efforts. We surveyed community members and individuals who had attended specific emergency departments for suicidal crisis. The respondents were part of a large-scale suicide prevention trial in New South Wales, Australia. The data collected included demographic characteristics, measures of help-seeking and suicide stigma. The linear regression analyses conducted sought to identify the factors …

Older Worker-Orientated Human Resource Practices, Wellbeing And Leave Intentions: A Conservation Of Resources Approach For Ageing Workforces, Ben Farr-Wharton, Tim Bentley, Leigh-Ann Onnis, Carlo Caponecchia, Abilio De Almeida Neto, Sharron O’Neill, Catherine Andrew

Research outputs 2022 to 2026

At a time where there are ageing populations, global shortages of skilled labour, and migration pathways impacted by the COVID-19 pandemic, retaining older workers presents as a vital strategic initiative for organizations globally. This study examines the role of Human Resource Practices (HRPs), which are oriented towards accommodating the needs of an ageing workforce in mitigating psychological distress and turnover intentions. The study collected self-reported survey data from 300 Australian employees over the age of 45, over two time points. Using structural equation modelling, the study analyzed the extent to which Older Worker-oriented Human Resources Practices (OW-HRPs) translate into employee …

Proposal For And Validation Of Novel Risk-Based Process To Reduce The Risk Of Construction Site Fatalities (Major Accident Prevention (Map) Program), Roberta Selleck, Marcus Cattani, Maureen Hassall

Research outputs 2022 to 2026

Despite developments in the prevention of fatalities in the construction industry, fatalities resulting from well-known hazards continue at an unacceptable rate. Construction fatality prevention literature describes risk management techniques to provide ‘early warning’ of potential events. In dynamic construction project environments, these ‘early warnings’ are missed resulting in serious and fatal events. Critical Control Risk Management (CCRM) provides an alternative strategy to prevent fatal events in the construction industry. However, no research exists that explores the application of CCRM to actual construction projects. This study aims to design, develop, and validate a construction fatality prevention program using CCRM principles through …

Continuing Legal Education In Germany – Digitalization, Dirk Hartung

Research Collection Yong Pung How School Of Law

Let me begin with a brief introduction to my home institution: Bucerius Law School in Hamburg, Germany. The school is named after Dr. Gerd Bucerius, a famous German publisher, politician and lawyer by training. Bucerius Law School, founded in 2000, is a private institution, which is atypical in Germany, where most of higher education institutions are publicly funded. In addition, Bucerius is rather small. We educate about 120 people per year and a total of 400-500 LL.B. students on our campus at any point in time. In addition, we offer a Master of Law and Business Program with 30 to …

Re-Innergized The Ministry Of The Holy Spirit, Stacey Spence-Baldwin

Doctor of Ministry

In this Project Portfolio, I will address the following NPO: The church is in decline or dying because it lacks connection with the Holy Spirit. Through the church relying on human reason instead of the will of the Holy Spirit, the church has lost its light. The key finding in my research is that when a church embraces the guidance of the Holy Spirit, it will live again. This finding came from my personal experiences of the Holy Spirit resurrecting three small rural churches which were in decline/death back to life. When congregations allowed the Holy Spirit to prompt their …