Digital Commons Network^™

Road Traffic Management Using Vehicle-To- Everything (V2x) Communication, Azzeddine Ben Khadra

Theses

Traffic congestion is the primary concern in dense cities; while the increased number of automobiles is becoming uncontrollable in some cities, it is more challenging to manage or change how people use cars. To contribute to solving traffic congestion in cities, this project examines the study of transferring vehicles to be competent in a way that can help the government entities analyze the received vehicles’ data and for better decisions on reducing traffic congestion as well as the real-time monitoring of traffic wherever it is located using the Vehicle-to-Everything (V2X) communication methodology. This study proposes a hardware “system” that can …

Empirical Investigations And Dataset Collection For American Sign Language-Aware Personal Assistants, Abraham Trout Glasser

Theses

Proliferation of voice-controlled personal-assistant devices poses accessibility barriers for Deaf and Hard of Hearing (DHH) users. It is estimated that 128 million people use a voice assistant in the United States, and 4.2 billion digital voice assistants being used around the world, e.g. through over 60,000 different smart home devices that support Amazon's Alexa, which is one instance of virtual assistants [97,134]. The ongoing (at the time of this dissertation) coronavirus pandemic has accelerated the uptake of home-based, voice-controlled devices. As artificial intelligence researchers and developers are working on American Sign Language (ASL) recognition technologies, Human-Computer Interaction (HCI) research is …

Would You Like Fries With That? Investigating Fast-Food Outlet Availability Near Schools In Perth, Western Australia, Gina S. A. Trapp, Paula Hooper, Wesley Billingham, Lukar Thornton, Ainslie Sartori, Kelly Kennington, Amanda Devine, Stephanie Godrich, Ros Sambell, Justine Howard, Alexia Bivoltsis

Research outputs 2022 to 2026

Issue addressed: Locating fast-food outlets near schools is a potential public health risk to schoolchildren, given the easy access and repeated exposure to energy-dense, nutrient-poor foods they provide. Fast-food outlet availability near schools has not been previously investigated in Perth, Western Australia. This study aimed to quantify fast-food outlet availability near Perth schools and determine whether differences in area-level disadvantage and school type exist. Methods: Fast-food outlet locations were sourced from Perth Local Governments in 2018/2019. All Perth Primary (n = 454), Secondary (n = 107) and K-12 (n = 94) schools were assigned an area-level disadvantage decile ranking based …

Learning Relation Prototype From Unlabeled Texts For Long-Tail Relation Extraction, Yixin Cao, Jun Kuang, Ming Gao, Aoying Zhou, Yonggang Wen, Tat-Seng Chua

Research Collection School Of Computing and Information Systems

Relation Extraction (RE) is a vital step to complete Knowledge Graph (KG) by extracting entity relations from texts. However, it usually suffers from the long-tail issue. The training data mainly concentrates on a few types of relations, leading to the lack of sufficient annotations for the remaining types of relations. In this paper, we propose a general approach to learn relation prototypes from unlabeled texts, to facilitate the long-tail relation extraction by transferring knowledge from the relation types with sufficient training data. We learn relation prototypes as an implicit factor between entities, which reflects the meanings of relations as well …

Magel2 Truncation Alters Select Behavioral And Physiological Outcomes In A Rat Model Of Schaaf-Yang Syndrome, Derek L Reznik, Mingxiao V Yang, Pedro Albelda De La Haza, Antrix Jain, Melanie Spanjaard, Susanne Theiss, Christian P Schaaf, Anna Malovannaya, Theresa V Strong, Surabi Veeraragavan, Rodney C Samaco

Faculty, Staff and Students Publications

Previous studies in mice have utilized Magel2 gene deletion models to examine the consequences of its absence. We report the generation, molecular validation and phenotypic characterization of a novel rat model with a truncating Magel2 mutation modeling variants associated with Schaaf-Yang syndrome-causing mutations. Within the hypothalamus, a brain region in which human MAGEL2 is paternally expressed, we demonstrated, at the level of transcript and peptide detection, that rat Magel2 exhibits a paternal, parent-of-origin effect. In evaluations of behavioral features across several domains, juvenile Magel2 mutant rats displayed alterations in anxiety-like behavior and sociability measures. Moreover, the analysis of peripheral organ …

The Roles Of Cyp1a2 And Cyp2d In Pharmacokinetic Profiles Of Serotonin And Norepinephrine Reuptake Inhibitor Duloxetine And Its Metabolites In Mice, Xuan Qin, Cen Xie, John M Hakenjos, Kevin R Mackenzie, Shelton R Boyd, Mercedes Barzi, Karl-Dimiter Bissig, Damian W Young, Feng Li

Faculty, Staff and Students Publications

Duloxetine (DLX) is widely used to treat major depressive disorder. Little is known about the mechanistic basis for DLX-related adverse effects (e.g., liver injury). Human CYP1A2 and CYP2D6 mainly contributes to DLX metabolism, which was proposed to be involved in its adverse effects. Here, we investigated the roles of Cyp1a2 and Cyp2d on DLX pharmacokinetic profile and tissue distribution using a Cyp1a2 knockout (Cyp1a2-KO) mouse model together with a Cyp2d inhibitor (propranolol). Cyp1a2-KO has the few effects on the systematic exposure (area under the plasma concentration-time curve, AUC) and tissue disposition of DLX and its primary metabolites. Propranolol dramatically increased …

Origin And Evolution Of Marsupial-Specific Imprinting Clusters Through Lineage-Specific Gene Duplications And Acquisition Of Promoter Differential Methylation, Wenqi Cao, Kory C. Douglas, Paul B. Samollow, John Vandeberg, Xu Wang, Andrew G. Clark

School of Medicine Publications

Genomic imprinting is a parent-of-origin-specific expression phenomenon that plays fundamental roles in many biological processes. In animals, imprinting is only observed in therian mammals, with ∼200 imprinted genes known in humans and mice. The imprinting pattern in marsupials has been minimally investigated by examining orthologs to known eutherian imprinted genes. To identify marsupial-specific imprinting in an unbiased way, we performed RNA-seq studies on samples of fetal brain and placenta from the reciprocal cross progeny of two laboratory opossum stocks. We inferred allele-specific expression for >3,000 expressed genes and discovered/validated 13 imprinted genes, including three previously known imprinted genes, Igf2r, Peg10, …

2023-02-01 2022 Was The Year Of Queer Country Music, Sam Bunn

The Spectator Online

No abstract provided.

2023-02-01 Connecting Post-Covid: Campus Traditions At Seattle U, George Burquest

The Spectator Online

No abstract provided.

2023-02-01 A Message To Students: Climate Change And The Perseverance Of Hope, Chloe Platt

The Spectator Online

No abstract provided.

2023-02-01 Non-Human Is Not Neutral: The Ethics Of Chatgpt, Madden Armstrong

The Spectator Online

No abstract provided.

2023-02-01 Opinion: 2023 Nba Midseason Takeaways: Playoff Picture Tightens, Lebron Nears All-Time Points Mark, Qasim Ali

The Spectator Online

No abstract provided.

2023-02-01 Paris Fashion Week Fall/Winter 2023: ‘Giving Hunger Games.’, Madi Oswalt

The Spectator Online

No abstract provided.

2023-02-01 Seattle University’S College Of Arts & Sciences Ceases Cr Grading Options, Simon Kidane

The Spectator Online

No abstract provided.

2023-02-01 Starbucks Stalls Progress In Labor Negotiations, Leila Bunker

The Spectator Online

No abstract provided.

2023-02-01 Strategic Directions Spark Conversation About Bipoc Students, Mckenna White

The Spectator Online

No abstract provided.

2023-02-01 Tech Layoffs And Business Closures Make Seattle’S Future Uncertain, Naja Johnson

The Spectator Online

No abstract provided.

2023-02-01 The Rise Of Fentanyl In King County: Is It A Concern For Seattle University?, Hisham Bensaadat

The Spectator Online

No abstract provided.

2023-02-01 Time Out Session: Riley Grigsby Reflects On Career At Seattle University, Tyra Okuda

The Spectator Online

No abstract provided.

2023-02-01 Week In Review: Jan. 25 – Jan. 31, Sean Campbell

The Spectator Online

No abstract provided.

Network Analysis Examining Intrahospital Traffic Of Patients With Traumatic Hip Fracture, Elizabeth A. Secor, David Hamilton, Cecile D'Huyvetter, Kristin Salottolo, David Bar-Or

GME Publications

Introduction: Increased intrahospital traffic (IHT) is associated with adverse events and infections in hospitalized patients. Network science has been used to study patient flow in hospitals but not specifically for patients with traumatic injuries.

Methods: This retrospective analysis included 103 patients with traumatic hip fractures admitted to a level I trauma center between April 2021 and September 2021. Associations with IHTs (moves within the hospital) were analyzed using R (4.1.2) as a weighted directed graph.

Results: The median (interquartile range) number of moves was 8 (7–9). The network consisted of 16 distinct units and showed mild disassortativity (−0.35), similar to …

Clinical And Functional Outcomes Of Reverse Total Shoulder Arthroplasty Supplemented With Latissimus Dorsi Transfer: A Systematic Review And Meta-Analysis, Jake X. Checketts, Robert Steele, Ashini Patel, Josh Stephens, Kate Buhrke, Arjun Reddy, Landon Stallings, Jacob J. Triplet, Brian Chalkin

GME Publications

Background: To optimize patients' functional external rotation outcomes, reverse total shoulder arthroplasties (rTSAs) including a latissimus dorsi tendon transfer were undertaken with promising early results and no significant increase in complications in comparison to traditional rTSAs. This was especially utilized for patients with a pronounced combined loss of elevation and external rotation. The purpose of this study is to evaluate and synthesize the findings of all relevant publications assessing the outcomes of rTSAs with associated latissimus dorsi transfer.

Methods: We thoroughly searched the literature within the PubMed database using a standardized methodology. For our inclusion criteria, we included any study …

The Performance Of Afp, Afp-3, Dcp As Biomarkers For Detection Of Hepatocellular Carcinoma (Hcc): A Phase 3 Biomarker Study In The United States, Nabihah Tayob, Fasiha Kanwal, Abeer Alsarraj, Ruben Hernaez, Hashem B El-Serag

Faculty, Staff and Students Publications

BACKGROUND & AIMS: α-fetoprotein (AFP), AFP Lens culinaris agglutinin-reactive fraction of AFP (AFP-L3), and des-gamma-carboxy prothrombin (DCP) in combination or in GALAD (Gender, Age, AFP-L3, AFP, and DCP) were tested for hepatocellular carcinoma (HCC) surveillance in retrospective cohort and case-control studies. However, there is a paucity of prospective data and no phase III biomarker studies from North American populations.

METHODS: We conducted a prospective specimen collection, retrospective blinded evaluation (PRoBE) cohort study in patients with cirrhosis enrolled in a 6-monthly surveillance with liver imaging and AFP. Blood samples were prospectively collected every 6 months and analyzed in a retrospective blinded …

Preschool-Aged Household Contacts As A Risk Factor For Viral Respiratory Infections In Healthcare Personnel, Zachary M Most, Ann-Christine Nyquist, Lewis J Radonovich, Maria C Rodriguez-Barradas, Connie Savor Price, Michael S Simberkoff, Mary T Bessesen, Derek A T Cummings, Susan M Rattigan, Charlotte Warren-Gash, Charlotte A Gaydos, Cynthia L Gibert, Geoffrey J Gorse, Trish M Perl

Faculty, Staff and Students Publications

BACKGROUND: Viral respiratory infections (VRIs) are common and are occupational risks for healthcare personnel (HCP). VRIs can also be acquired at home and other settings among HCPs. We sought to determine if preschool-aged household contacts are a risk factor for VRIs among HCPs working in outpatient settings.

METHODS: We conducted a secondary analysis of data from a cluster randomized trial at 7 medical centers in the United States over 4 influenza seasons from 2011-2012 to 2014-2015. Adult HCPs who routinely came within 6 feet of patients with respiratory infections were included. Participants were tested for respiratory viruses whenever symptomatic and …

Associations Of Serum And Dialysate Potassium Concentrations With Incident Atrial Fibrillation In A Cohort Study Of Older Us Persons Initiating Hemodialysis For Kidney Failure, Austin Hu, Sai Liu, Maria E Montez-Rath, Pascale Khairallah, Jingbo Niu, Mintu P Turakhia, Tara I Chang, Wolfgang C Winkelmayer

Faculty, Staff and Students Publications

INTRODUCTION: Atrial fibrillation (AF) disproportionally affects persons on maintenance hemodialysis (HD). Associations of serum and dialysate potassium concentrations [K+] with AF incidence are poorly understood.

METHODS: We conducted a cohort study using Medicare claims merged with clinical data from a dialysis provider to determine whether serum-[K+] and/or dialysate-[K+] independently associated with AF incidence. Persons insured by fee-for-service Medicare aged ≥67 years at dialysis initiation and free from diagnosed AF prior to day 120 of dialysis were eligible. Serum-[K+] and dialysate-[K+] were assessed in 30-day intervals and patients were followed-up with for AF incidence in subsequent 30-day intervals.

RESULTS: During 2006 …

When Shortness Of Breath Gets Misdiagnosed: Atrial Myxoma Case Report, Sahaam Mirza, Tori Tyler, Robert Stauffer

Student Publications

The vague presentation of an atrial myxoma makes accurate diagnosis difficult. This case report reviews the case of a 54-year-old female who presented to the Emergency Department complaining of shortness of breath and back pain. Prior to her Emergency Department evaluation, she had been given a diagnosis with pneumonia. Upon further evaluation, she was diagnosed with a large left atrial myxoma that was surgically removed via median sternotomy. After recovering from her surgery, the patient had a full resolution of her symptoms. Although the treatment for myxomas has a high success rate of full recovery, the difficulty in diagnosis poses …

A Systematic Review And Meta-Analysis Of The Association Between Sars-Cov-2 Vaccination And Myocarditis Or Pericarditis, Juan Gao, Linya Feng, Yaru Li, Scott Lowe, Zhichun Guo, Rachel Bentley, Chuman Xie, Birong Wu, Peng Xie, Weihang Xia, Shaodi Ma, Haixia Liu, Xianwei Guo, John Patrick Nanola Uy, Qin Zhou, Hina Wazir, Chenyu Sun

Student Publications

Introduction: There have been reports of potential negative cardiovascular effects from the COVID-19 vaccine, such as myocarditis or pericarditis. This study sought to ascertain the risk of myocarditis/pericarditis after COVID-19 vaccination by conducting an extensive meta-analysis of published cases.

Methods: A systematic literature search was conducted in 7 online databases by March 31, 2022. Heterogeneity was tested by I2 index. RR and 95% CI were pooled through either random-effect or fixed-effect models. Sensitivity analysis and publication bias were also conducted.

Results: A total of 11 studies with 58,620,611 subjects were included. COVID-19 vaccination correlated with an increased risk of myocarditis …

Combinatorial Identities Associated With A Bivariate Generating Function For Overpartition Pairs, Atul Dixit, Ankush Goswami

School of Mathematical & Statistical Sciences Faculty Publications

We obtain a three-parameter q-series identity that generalizes two results of Chan and Mao. By specializing our identity, we derive new results of combinatorial significance in connection with N(r,s,m,n), a function counting certain overpartition pairs recently introduced by Bringmann, Lovejoy and Osburn. For example, one of our identities gives a closed-form evaluation of a double series in terms of Chebyshev polynomials of the second kind, thereby resulting in an analogue of Euler's pentagonal number theorem. Another of our results expresses a multi-sum involving N(r,s,m,n) in terms of just the partition function p(n). Using a result of Shimura we also relate …

Coloring Complexes And Combinatorial Hopf Monoids, Jacob A. White

School of Mathematical & Statistical Sciences Faculty Publications

We generalize the notion of a coloring complex of a graph to linearized combinatorial Hopf monoids. We determine when a linearized combinatorial Hopf monoid has such a construction, and discover some inequalities that are satisfied by the quasisymmetric function invariants associated to the combinatorial Hopf monoid. We show that the collection of all such coloring complexes forms a linearized combinatorial Hopf monoid, which is the terminal object in the category of combinatorial Hopf monoids with convex characters. We also study several examples of combinatorial Hopf monoids.

On Viscoelastic Fiber Jet Formation By Forcespinning At High Rotation Rate, Daniel N. Riahi, Saulo Orizaga

School of Mathematical & Statistical Sciences Faculty Publications

We consider a nonlinear three-dimensional viscoelastic fiber jet that is generated during a forcespinning process. We provide a particular case for such a rotating jet at a high rotation rate. We use a viscoelastic constitutive model for the jet equations and then applying a new slender body approach, we continue with proper scaling and perturbation technique to develop a new model for such a jet system. We find that the profiles for jet quantities versus arc length are notably different from all those in related studies reported before for either high or low rotation rates. In particular, jet radius first …