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Great Division In The United States & How To Implement Unification, Hadley Grace Blansfield Apr 2026

Great Division In The United States & How To Implement Unification, Hadley Grace Blansfield

Senior Honors Theses

Today’s political hostility is largely due to political parties and extreme political perspectives. This paper will demonstrate the historical background regarding political divide that has plagued America over the past 200 years. In addition, other issues such as modern-day violence, violence due to political conflict, social and political segregation, and the monopolization by the Democratic and Republican parties will be referenced and connected with political party conflict. While political parties are the root cause of the violence and division within the United States, external triggers are also at play at exacerbating the divide of political parties which will be reviewed. …


The Cost Of Cargo Preference: How Shipping Requirements Hinder Food Aid Efficiency, Grace E. Pattara Apr 2026

The Cost Of Cargo Preference: How Shipping Requirements Hinder Food Aid Efficiency, Grace E. Pattara

Senior Honors Theses

Cargo preference for food aid (CPFA) mandates that 50 percent of U.S. food aid shipments be transported on U.S.-flagged vessels (USFVs). However, only seven USFVs are equipped to accommodate bulk food aid, causing shipments to be sent on vessels not designed for such transport. This constraint increases operational costs by an average of 270 percent, delays delivery timelines, and consumes 30-50 percent of the food aid budget. As the American legislature stands in an important moment in foreign aid history when U.S. foreign assistance is being fundamentally restructured, this thesis argues that Congress should repeal CPFA and permit competitive bidding …


Leadership Challenges In Achieving Healthcare Interoperability: A Cross-Sectional Survey Of Patient Experiences, Hoshiar J. Sher Apr 2026

Leadership Challenges In Achieving Healthcare Interoperability: A Cross-Sectional Survey Of Patient Experiences, Hoshiar J. Sher

Education Doctoral

Healthcare interoperability remains constrained not only by technical barriers but also by leadership, governance, and administrative fragmentation. The purpose of this quantitative cross-sectional study was to examine how leadership-related barriers to interoperability were reflected in patients’ and caregivers’ experiences with administrative clarity, system integration complexity, trust in leadership, satisfaction, and switching behavior. Guided by transformational leadership theory, data were collected through an online survey of 435 U.S. adults who managed healthcare administrative tasks for themselves or family members. Descriptive, subgroup, and multivariable analyses were conducted to address five research questions. Respondents reported moderate coverage clarity and billing ease, elevated billing …


Analysis Of Lateral Load Distribution In Steel Girder–Concrete Deck Bridges: Influence Of Diaphragm Behavior Under Wind And Vessel Collision Loads, Bhupesh Chand Apr 2026

Analysis Of Lateral Load Distribution In Steel Girder–Concrete Deck Bridges: Influence Of Diaphragm Behavior Under Wind And Vessel Collision Loads, Bhupesh Chand

Master's Theses

Bridges are critical components of modern transportation infrastructure, and their structural response under extreme loading conditions is essential for ensuring safety and serviceability. A key challenge in current bridge engineering practice is accurately understanding and predicting the lateral load distribution in steel girder–concrete deck bridge systems subjected to wind and vessel collision loads. While the AASHTO LRFD Bridge Design Specifications provide well-established provisions for vertical load distribution, magnitudes and load combinations (Article 3.4), they do not explicitly define lateral load distribution factors (LLDFs) for such extreme lateral loading conditions or address the role of the deck in redistributing these loads …


Implementing And Evaluating A Mental Health Education And Mindfulness Program For Police Officers, Patricia Lynn Young Apr 2026

Implementing And Evaluating A Mental Health Education And Mindfulness Program For Police Officers, Patricia Lynn Young

Doctor of Nursing Practice

Background: Police officers are routinely exposed to occupational stress and trauma, contributing to an increased risk of anxiety, depression, substance misuse, and post-traumatic stress disorder (PTSD). Targeted mental health interventions are needed to proactively address their mental health. Purpose: This Doctor of Nursing Practice (DNP) project implemented and evaluated a mental health education and mindfulness program designed to reduce operational stress and increase knowledge and use of departmental mental health resources and mindfulness techniques among police officers. Methods: A pre–post intervention design was used over a 10-week period. Participants (n = 14) completed the Operational Police Stress Questionnaire (PSQ-Op) and …


Evaluation Of The Prevention And Management Of Assaultive Behaviors (Pmab) Training For Outpatient Ambulatory Care Staff, Michaela Bowles Apr 2026

Evaluation Of The Prevention And Management Of Assaultive Behaviors (Pmab) Training For Outpatient Ambulatory Care Staff, Michaela Bowles

Doctor of Nursing Practice

Background: Workplace violence (WPV) disproportionately affects healthcare workers and harms both staff well-being and the healthcare organization. Despite growing attention to WPV prevention, effective solutions remain limited. The purpose of this project was to evaluate the Prevention and Management of Assaultive Behaviors (PMAB) training in an outpatient ambulatory care setting and to assess staff’s confidence and ability to respond to escalating situations. Methods: A pre/post observational survey using Likert-scale, multiple choice, yes/no questions and narrative responses measured confidence before, immediately after, and 3 to 12 months following PMAB training. A retrospective review of WPV incident reports three months before and …


Mindbodystrong: A Pilot To Address Nursing Burnout & To Promote Wellness, Leilah Hunt Apr 2026

Mindbodystrong: A Pilot To Address Nursing Burnout & To Promote Wellness, Leilah Hunt

Doctor of Nursing Practice

Background: Nursing burnout rates have increased significantly since the Covid-19 pandemic, not only within the United States but throughout the world. As burnout is multifaceted in nature, identifying and addressing the root cause of burnout has been challenging. One approach to remedy burnout effects is by enhancing wellness through daily practice of healthy habits. Purpose: The purpose of this DNP project was to pilot and evaluate the effects of the MINDBODYSTRONG Cognitive Behavioral Skills Building Program on self-rated anxiety, stress, depressive symptoms, and burnout symptoms in a sample population of nurses at a large psychiatric hospital. This program has …


Measuring Provider Confidence In Using Long-Acting Injectable Antipsychotics In Hospitalized Adults With Schizophrenia Spectrum Disorders, Rachel Mccluskey Apr 2026

Measuring Provider Confidence In Using Long-Acting Injectable Antipsychotics In Hospitalized Adults With Schizophrenia Spectrum Disorders, Rachel Mccluskey

Doctor of Nursing Practice

Background: Schizophrenia spectrum disorders are severely disabling conditions requiring ongoing pharmacological management. Rates of medication nonadherence among individuals with schizophrenia spectrum disorder are high and strong evidence exists for the benefits of long-acting injectable antipsychotics (LAI) over oral antipsychotics. Despite this, only 10% of patients in Washington State with schizophrenia spectrum disorders are administered longacting injectable antipsychotics. Purpose: The purpose of this project was to measure change in provider’s confidence in prescribing LAI for hospitalized patients with schizophrenia spectrum disorders following one-on-one motivational information (MI) style informational/discussion sessions coupled with a prescribing reference. Methods: This quality improvement project surveyed provider’s …


Oorja Development Solutions Multi-Outlet Water Delivery System, Yared Calderon, Paul Trudell Apr 2026

Oorja Development Solutions Multi-Outlet Water Delivery System, Yared Calderon, Paul Trudell

General Engineering

Oorja Development Solutions deploys and operates solar-powered irrigation systems that provide water access to smallholder farmers in rural India. The company’s existing single-outlet irrigation design is inefficient, restricts access to one user at a time, increasing irrigation wait times, underutilizing pump capacity, and limiting the total volume of water delivered each day.

This project was conducted in collaboration with the Santa Clara University Miller Center for Social Entrepreneurship and Oorja Development Solutions to investigate methods for improving water-distribution efficiently while maintaining compatibility with Oorja’s existing solar-powered infrastructure. The project included hydraulic analysis of the existing piping system, development of a …


Staying Power: A Case Study Of Teacher Retention In A Rural District, Amanda F. Mclellan, Amanda F. Mclellan Apr 2026

Staying Power: A Case Study Of Teacher Retention In A Rural District, Amanda F. Mclellan, Amanda F. Mclellan

Electronic Theses and Dissertations

Teacher attrition continues to be a significant challenge in K-12 education, particularly in rural school districts where limited resources and geographic isolation can intensify staffing instability. While much research has focused on teacher attrition, little research examines why tenured teachers choose to remain in rural districts. The purpose of this qualitative, single-case study was to examine the experiences and insights of tenured teachers regarding their decision to continue teaching in a small, rural Texas school district. Guided by Mason and Matas’s fourcapital framework for teacher retention, this study examined how human, social, structural, and positive psychological capital influenced teachers’ decisions …


The Implications Of The Midyear Departure Of Residence Directors In Housing And Residential Life, Chelsea Titus Apr 2026

The Implications Of The Midyear Departure Of Residence Directors In Housing And Residential Life, Chelsea Titus

Electronic Theses and Dissertations

High attrition rates among entry-level student affairs professionals have been documented for decades, yet little research has examined the implications of midyear departures within housing and residential life. Residence directors serve as live-in professionals responsible for crisis response, student conduct, staff supervision, and community development. When a midyear departure occurs, the disruption extends beyond the vacancy and affects supervisors, colleagues, and residential communities. The problem addressed in this study was the organizational and supervisory impact of midyear residence director departures. The purpose of this qualitative narrative inquiry was to examine the factors contributing to midyear departures and to explore how …


Leading The Charge: A Qualitative Descriptive Study Exploring How Public Middle School Principals Perceive And Enact Their Role As Advocates For School-Based Mental Health, Tanya Irby Tucker Apr 2026

Leading The Charge: A Qualitative Descriptive Study Exploring How Public Middle School Principals Perceive And Enact Their Role As Advocates For School-Based Mental Health, Tanya Irby Tucker

Electronic Theses and Dissertations

Adolescent mental health concerns have increased significantly during the middle school years, requiring school leaders to expand their role in supporting students’ social, emotional, and psychological well-being. Although schools are uniquely positioned to deliver comprehensive mental health services, how public middle school principals perceive and enact their role as advocates for school-based mental health services remains underexplored. The purpose of this qualitative descriptive study was to explore how public middle school principals perceive and enact their role as advocates for school-based mental health services. Guided by social cognitive theory (SCT), this study examined how personal beliefs, behavioral practices, and environmental …


Exploring The Way Up: Career Paths, Challenges, And Resilience Among Women Leaders In Higher Education, Angela M. Brown Apr 2026

Exploring The Way Up: Career Paths, Challenges, And Resilience Among Women Leaders In Higher Education, Angela M. Brown

Electronic Theses and Dissertations

Women represent the majority of students and faculty in higher education students in higher education in the United States, yet they remain underrepresented in executive leadership positions. Women pursuing these roles encounter unique challenges, and institutions have increasingly recognized the value of mentoring and sponsoring women who aspire to leadership. Guided by Kumar’s CR8 resilience theory, this qualitative descriptive study explored how women leaders in higher education in the United States describe their career pathways to leadership, the challenges they encounter, and the impact of mentoring/sponsoring in developing their resilience for career progression. Semistructured interviews were conducted with 11 women …


Bridging The Divide: Exploring Stigma And Enhancing Belonging For Online Faculty In Higher Education, Stephanie L. Wanamaker Apr 2026

Bridging The Divide: Exploring Stigma And Enhancing Belonging For Online Faculty In Higher Education, Stephanie L. Wanamaker

Electronic Theses and Dissertations

Online faculty in higher education experience stigma and negative perceptions regarding online education in academia. Despite the rapid growth and success of online education, negative perceptions and stigma have not evolved at the same pace as the success of online institutions. Many online faculty members frequently experience skepticism, criticism, and marginalization from their residential counterparts within their academic communities. As a result of these experiences, online faculty are experiencing a reduced level of belonging, contributing to increased levels of burnout, poor satisfaction, and struggles with professional identity. Despite these experiences, little is known about the problem or how online faculty …


Transformative Leadership In Action: A Narrative Study Of Principals’ Influence On Students’ Achievement, Staci Taylor Fullmighter Apr 2026

Transformative Leadership In Action: A Narrative Study Of Principals’ Influence On Students’ Achievement, Staci Taylor Fullmighter

Electronic Theses and Dissertations

This narrative inquiry examined how principals in low-performing high-minority urban schools use transformational leadership to improve academic outcomes. The purpose of this research was to describe principals’ leadership behaviors that are perceived to positively influence academic achievement among students who identify as minority and low socioeconomic status and are attending or have attended urban school districts with high concentrations of the identified population. Data were collected through semistructured interviews with principals, and narratives were studied to identify trends across their experiences. Four themes emerged: (a) trust and shared accountability, (b) encouraging creativity and risk-taking, (c) communicating shared goals, and (d) …


Influence Of Restorative Justice Practices On Student Behavior, Shawn N. Clemons Apr 2026

Influence Of Restorative Justice Practices On Student Behavior, Shawn N. Clemons

Electronic Theses and Dissertations

The purpose of this qualitative exploratory case study was to explore how teachers in culturally diverse suburban U.S. elementary schools perceive the implementation of restorative justice practices as an influence on student behavior. The researcher collected data through questionnaires and semistructured interviews of 14 elementary teachers currently employed in a suburban elementary school who actively use restorative justice with students. Findings from the study indicated the restorative justice practices contribute positively to school culture by prioritizing relationship building, structured conflict resolution, and inclusive practices. The findings from this study can be used with teachers, administrators, district support, and school board …


African American Male Dual Enrollment Graduates Perceptions Of The Transition To The 4-Year University, Kendra L. Harrison Apr 2026

African American Male Dual Enrollment Graduates Perceptions Of The Transition To The 4-Year University, Kendra L. Harrison

Electronic Theses and Dissertations

The purpose of this qualitative exploratory case study was to explore how African American men who earned an associate degree from dual enrollment programs in Texas perceive the transition to a 4-year university to pursue a bachelor’s degree. The 4S model of Schlossberg’s transition theory was the conceptual framework that undergirded the study. Purposive sampling was used to recruit 20 participants. The researcher collected and triangulated data using a questionnaire and semistructured interviews and analyzed it using six-step thematic analysis. Results revealed competence and confidence from dual enrollment program resulted in a smooth transition to college, participants’ African American male …


Identifying The Barriers Bilingual Parents Face In The Special Education Process, Miranda Leah Hernandez Apr 2026

Identifying The Barriers Bilingual Parents Face In The Special Education Process, Miranda Leah Hernandez

Electronic Theses and Dissertations

Increasing parental involvement in the special education process means parents, teachers, and school administrators can unite to educate the children. The problem that the researcher identified was that emergent bilingual families struggle to become meaningful participants in their children’s individualized education plans. This was a qualitative case study that identified the barriers that bilingual parents face within the special education process and the recommendations from bilingual parents on how to help them become more meaningful members of their child’s individualized education plan. The population within the research included bilingual families with children in the greater Houston, Texas area who have …


The “One Big Beautiful Bill” Will Deepen The Farm Crisis, Not Solve It, Rebecca Schewe, Rick Welsh Apr 2026

The “One Big Beautiful Bill” Will Deepen The Farm Crisis, Not Solve It, Rebecca Schewe, Rick Welsh

Center for Policy Research

The One Big Beautiful Bill (OBBB) promises billions in new farm subsidies, but most of that money won’t go to the farmers who need it most. This brief describes how the OBBB’s changes to agricultural subsidy programs will disproportionately benefit large farms and non-farming investors, accelerating farm loss and consolidation across the United States. The authors argue that without reforms, the OBBB will inflate land values, raise barriers for new and small farmers, and further fuel absentee farmland investment. The authors also identify four reforms policymakers should enact to prevent these devastating consequences, including tightening payment limits and closing loopholes, …


Neurogen: Effects Of Near-Infrared Light Stimulation On Cognition And Eeg Biomarkers, Damilola Gbadamosi, Cassie Hashemi, Taj Keny Apr 2026

Neurogen: Effects Of Near-Infrared Light Stimulation On Cognition And Eeg Biomarkers, Damilola Gbadamosi, Cassie Hashemi, Taj Keny

Interdisciplinary Design Senior Theses

Concussion is the most common form of traumatic brain injury, and a substantial fraction of those affected develop post-concussion syndrome (PCS), a condition characterized by persistent cognitive, emotional, physical, and sleep symptoms for which no definitive treatment currently exists. Transcranial photobiomodulation (tPBM), the delivery of near-infrared (NIR) light to brain tissue, has shown promise for addressing the metabolic dysfunction that underlies concussion. Still, commercially available tPBM devices rely on fixed, open-loop protocols and do not integrate electroencephalography (EEG), limiting a clinician’s ability to monitor neural biomarkers during treatment. Our team’s objective was to develop a system that utilizes tPBM to …


Blink & Beat: Pupillometry Response In Autonomic Nervous System Monitoring, Ximena Castillo Apr 2026

Blink & Beat: Pupillometry Response In Autonomic Nervous System Monitoring, Ximena Castillo

2026 Spring Honors Capstones Projects

In the neuroscience intensive care unit (NSICU), nurses rely on advanced monitoring tools to detect neurological deterioration. Two noninvasive measures, heart rate variability (HRV) and pupillary light reflex (PLR), are used to assess autonomic nervous system function; however, it remains unclear whether these indicators provide overlapping or distinct information. The purpose of this observational prospective study is to evaluate the relationship between HRV and quantitative pupillometry measurements to determine whether these noninvasive indicators provide congruent information. Data already collected as routine care from NSICU patients is extracted from the medical record for analysis. Understanding the correlation between HRV and PLR …


The Guardian The Month Of April 2026, Wright State Student Body Apr 2026

The Guardian The Month Of April 2026, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of April 2026. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


How Media Framing Impacts Juror Bias In A Fictional Criminal Case, Teah Sharon Swartzon Apr 2026

How Media Framing Impacts Juror Bias In A Fictional Criminal Case, Teah Sharon Swartzon

Journalism

This study examines how media framing influences juror bias among college-aged students when evaluating a defendant's guilt in a fictional criminal case. Utilizing framing theory, the research explores whether biased news coverage can shape perceptions of a defendant's guilt before trial.

Participants, consisting of students at California Polytechnic State University, aged 18-22, were asked to read two news articles about a fictional criminal case. One framed the fictional defendant as guilty, while the other framed him as innocent. Both articles were generated using the Artificial Intelligence Platform, Claude.

Data was collected in a survey where participants indicated whether they believed …


Reducing Humpty Dumpty Syndrome In Pediatric Inpatients, Jeanene Burns Apr 2026

Reducing Humpty Dumpty Syndrome In Pediatric Inpatients, Jeanene Burns

Electronic Theses and Dissertations

The Doctor of Nursing Practice project examined pediatric inpatient falls. The healthcare agency involved in the project identified concerns regarding pediatric inpatient falls. Data were collected on pediatric inpatient falls that occurred on two nursing units at this agency based on the Generalized Risk Assessment for Pediatric Inpatient Falls and the Humpty Dumpty Falls Prevention Scale. Results from the project indicated marginal statistical significance, with approximately a 60% reduction in falls after the implementation of the Humpty Dumpty Falls Prevention Scale. A recommendation for future research is a comparison of the two pediatric fall risk assessment tools after the Humpty …


Advancing Paleontologic Mapping: A Gis And Drone Photogrammetry Approach To The Lance Formation Beds Of Glenrock, Wyoming, William H. Steelman, Monika Angner, Norman S. Levine, W S. Persons Apr 2026

Advancing Paleontologic Mapping: A Gis And Drone Photogrammetry Approach To The Lance Formation Beds Of Glenrock, Wyoming, William H. Steelman, Monika Angner, Norman S. Levine, W S. Persons

The Compass: Earth Science Journal of Sigma Gamma Epsilon

Small museums and volunteer-driven field programs often lack the resources required for detailed geological mapping, limiting the stratigraphic data associated with their fossil collections. To address this challenge, an affordable and replicable mapping workflow was developed that combined drone-based photogrammetry, GIS analysis, and targeted structural measurements using the Glenrock Exposure of the Lance Formation as a study site. The resulting 3D outcrop models, bedding-plane reconstructions, and 750-m-thick stratigraphic column provide the first comprehensive spatial framework for 35 fossil quarries curated by the Glenrock Paleon Museum. The results reveal tightly clustered fossil-bearing horizons, a long interval lacking preservation, and a notable …


Sigma Gamma Epsilon Student Research Poster Session, Geological Society Of America Annual Meeting 2025, San Antonio, Texas, Usa, Scott R. Beason, Lee S. Potter Apr 2026

Sigma Gamma Epsilon Student Research Poster Session, Geological Society Of America Annual Meeting 2025, San Antonio, Texas, Usa, Scott R. Beason, Lee S. Potter

The Compass: Earth Science Journal of Sigma Gamma Epsilon

The Society of Sigma Gamma Epsilon (SGE) sponsors a poster session at every annual meeting of the Geological Society of America. The 37th SGE undergraduate research poster session took place during the 2025 Geological Society of America Annual Meeting (GSA Connects) in San Antonio, Texas, USA, on Monday, October 20, 2025. Fifty-seven (57) posters were presented in Exhibit Hall 1 at the Henry B. Gonzalez Convention Center between 8:30 AM and 5:30 PM at the poster session, with authors present between 9:00 AM and 11:00 AM. Titles, authors (italics for the presenting author), affiliations, and abstracts for each poster are …


Dental Insurance Status Among Formerly Incarcerated Older Adults, Alexander Testa, Rafael Samper-Ternent, Dylan B Jackson, Kyle T Ganson, Vahed Maroufy, Jason M Nagata, Ana C Neumann Apr 2026

Dental Insurance Status Among Formerly Incarcerated Older Adults, Alexander Testa, Rafael Samper-Ternent, Dylan B Jackson, Kyle T Ganson, Vahed Maroufy, Jason M Nagata, Ana C Neumann

Faculty, Staff and Student Publications

Formerly incarcerated individuals have poorer oral health and less frequent dental care utilization than the general population. However, prior work has overlooked the relationship between prior incarceration and disparities in dental insurance coverage. Using data from the Health and Retirement Study (n = 11,638), findings from multiple logistic regression analyses demonstrate that formerly incarcerated older adults are significantly less likely to have dental insurance coverage (odds ratio [OR] = 0.745, 95% confidence interval [CI] = 0.608, 0.912). After accounting for the income-to-poverty ratio, this association was no longer statistically significant. Analyses using the Karlson-Holm-Breen method demonstrated that approximately 45% of …


Sexual Health And Relationship Education Needs Of People In Recovery For An Opioid Use Disorder, J Michael Wilkerson, Kathryn R Gallardo, I Niles Zoschke, Hannah L N Stewart, Serena A Rodriguez, Michael U Anosike, Jason Pullin, Sheryl A Mccurdy Apr 2026

Sexual Health And Relationship Education Needs Of People In Recovery For An Opioid Use Disorder, J Michael Wilkerson, Kathryn R Gallardo, I Niles Zoschke, Hannah L N Stewart, Serena A Rodriguez, Michael U Anosike, Jason Pullin, Sheryl A Mccurdy

Faculty, Staff and Student Publications

People in recovery with histories of sex and drug-linked behavior (SDB) have an increased risk of substance use recurrence. However, sexual health concerns remain largely unaddressed by recovery support services researchers and practitioners. The purpose of this analysis was to describe the sex and relationship concerns of people in recovery for an opioid use disorder living in level II and level III recovery homes. Recovery homes are sober living homes that the National Association for Recovery Residences classifies into four levels based on staffing and service provision. We interviewed 93 residents and thematically analyzed 92 of the resulting transcripts; one …


Robo2 Variants Associated With Atrial Septal Defect Define A Novel Regulatory Element, Seong Won Kim, Michael Parfenov, Laura Rodriguez-Murillo, David A Conner, Arun Sharma, Inga Peter, Feng Xiao, Olivia Layton, Angela Tai, Tarsha Ward, Lauren K Wasson, Joshua M Gorham, Erica Mazaika, Valentina N Lagomarsino, Tracy L Young-Pearse, Elizabeth Goldmuntz, Hiroko Wakimoto, A J Agopian, David M Mckean, Steven R Depalma, William T Pu, Christine E Seidman, Bruce D Gelb, Jonathan G Seidman Apr 2026

Robo2 Variants Associated With Atrial Septal Defect Define A Novel Regulatory Element, Seong Won Kim, Michael Parfenov, Laura Rodriguez-Murillo, David A Conner, Arun Sharma, Inga Peter, Feng Xiao, Olivia Layton, Angela Tai, Tarsha Ward, Lauren K Wasson, Joshua M Gorham, Erica Mazaika, Valentina N Lagomarsino, Tracy L Young-Pearse, Elizabeth Goldmuntz, Hiroko Wakimoto, A J Agopian, David M Mckean, Steven R Depalma, William T Pu, Christine E Seidman, Bruce D Gelb, Jonathan G Seidman

Faculty, Staff and Student Publications

Background: Atrial septal defects (ASDs) are a prevalent type of congenital heart disease. Previous GWAS (Genome-Wide Association Studies) have identified common variants associated with ASDs, though their mechanisms remain unknown. We aimed to expand insights into the architecture of common variants associated with ASD risk and elucidate functional mechanisms.

Methods: We conducted a GWAS using isolated ASD cases and healthy controls and replicated findings in an independent cohort. We examined epigenetic marks within this ASD locus in human induced pluripotent stem cell-derived cardiomyocytes and fetal human hearts. We characterized the consequences of deletions introduced by CRISPR-Cas9 mutagenesis of human induced …


Developing Scenario-Based Strategies For Health, Climate, And Environmental Preparedness: The One Health, One Earth Approach, Azar M Abadi, Kyle D Brumfield, Moiz Usmani, Gemma Jiang, T C Chakraborty, Yuzhou Wang, Zhijie Zhou, Cenlin He, Minghao Qiu, Jennifer D Stowell, Douglas Fritz, Sunil Kumar, Qiang Guo, Ying Xiong, Georgia Destouni, Qian Xiao, Xindi C Hu, Kelvin C Fong, Yun Hang, John Nielsen-Gammon, Rima Habre, Jennifer R Bratburd, Christopher W Tessum, Antarpreet Jutla, Rita R Colwell, Gabriel M Filippelli, Thanh H Nguyen Apr 2026

Developing Scenario-Based Strategies For Health, Climate, And Environmental Preparedness: The One Health, One Earth Approach, Azar M Abadi, Kyle D Brumfield, Moiz Usmani, Gemma Jiang, T C Chakraborty, Yuzhou Wang, Zhijie Zhou, Cenlin He, Minghao Qiu, Jennifer D Stowell, Douglas Fritz, Sunil Kumar, Qiang Guo, Ying Xiong, Georgia Destouni, Qian Xiao, Xindi C Hu, Kelvin C Fong, Yun Hang, John Nielsen-Gammon, Rima Habre, Jennifer R Bratburd, Christopher W Tessum, Antarpreet Jutla, Rita R Colwell, Gabriel M Filippelli, Thanh H Nguyen

Faculty, Staff and Student Publications

Climate change amplifies many threats to human health. Despite advances in understanding climate change dynamics and impacts, there remains a critical gap in translating scientific knowledge into equitable, and community‐driven health interventions. The inaugural One Earth, One Health workshop sought to explore this gap through human‐centered design exercises involving interdisciplinary researchers from climate and Earth sciences, engineering, epidemiology, microbiology, and environmental health. Although participants did not co‐develop solutions with affected communities, they used stakeholder role‐playing to guide ideation and lay groundwork for actionable plans. Through these methods, participants identified community needs and proposed prototype solutions to alleviate health threats …