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Articles 575611 - 575640 of 5158626
Full-Text Articles in Entire DC Network
Confucius, Wisdom, And Political Participation: Benevolence And Timeliness In The Analects, Sydney Morrow, Shane Ryan
Confucius, Wisdom, And Political Participation: Benevolence And Timeliness In The Analects, Sydney Morrow, Shane Ryan
Research Collection School of Social Sciences
This paper aims to address when the wise person should participate in politics. The question is addressed through engagement with the Analects. Rather than provide interpretations of key terms in the Analects, we provide an account of wisdom that draws from themes in the Analects. The case is made that the wise person is committed to participating in politics primarily because of the connection between wisdom and benevolence (ren 仁 in the Analects). We address challenges to the Confucian approach from the Zhuangzi concerning the potential harms of political participation. General political disengagement is not considered exemplary on the Confucian …
Disentangling The Effects Of Smartphone Screen Time, Checking Frequency, And Problematic Use On Executive Function: A Structural Equation Modelling Analysis, Wei Xing Toh, Wee Qin Ng, Hwajin Yang, Sujin Yang
Disentangling The Effects Of Smartphone Screen Time, Checking Frequency, And Problematic Use On Executive Function: A Structural Equation Modelling Analysis, Wei Xing Toh, Wee Qin Ng, Hwajin Yang, Sujin Yang
Research Collection School of Social Sciences
The pervasiveness of smartphone engagement among young adults has attracted growing interest regarding its impact on cognitive processes. However, research on the relation between smartphone use and executive function (EF)—a set of adaptive, goal-directed control processes—remains inconclusive due to imprecise estimation of EF dimensions and inconsistent operationalisation of smartphone use in past studies. Therefore, we examined how two indices of smartphone use—screen time and checking frequency—would predict EF (common EF, shifting-specific-, and working-memory-specific components), using a latent-variable approach based on a comprehensive battery of EF tasks. We also examined the moderating role of problematic smartphone use in the link between …
Effects Of Positive Reappraisal And Self-Distancing On The Meaningfulness Of Everyday Negative Events, Clement Yong Hao Lau, William Tov
Effects Of Positive Reappraisal And Self-Distancing On The Meaningfulness Of Everyday Negative Events, Clement Yong Hao Lau, William Tov
Research Collection School of Social Sciences
Current work on meaning-making has primarily focused on major negative life events such as trauma and loss, leaving common daily adversities unexplored. This study aimed to examine how utilizing meaning-making strategies such as positive reappraisal and self-distancing (in isolation or in combination) can facilitate an adaptive processing of these daily negative experiences. Overall meaning and facets of meaning (coherence, purpose, and significance/mattering) were assessed at both global and situational levels. Results suggested that positive reappraisal was generally effective for enhancing situational meaning but not under all conditions. Specifically, when negative experiences were high on emotional intensity, reflecting on the experience …
A Narrative Review Of Screen Time And Wellbeing Among Adolescents Before And During The Covid-19 Pandemic: Implications For The Future, Verity Yu Qing Lua, Terence B. K. Chua, Michael Y. H. Chia
A Narrative Review Of Screen Time And Wellbeing Among Adolescents Before And During The Covid-19 Pandemic: Implications For The Future, Verity Yu Qing Lua, Terence B. K. Chua, Michael Y. H. Chia
Research Collection School of Social Sciences
The COVID-19 pandemic has disrupted the lives of many. In particular, during the height of the pandemic, many experienced lockdowns, which in turn increased screen time drastically. While the pandemic has been declared an endemic and most activities have been reinstated, there appears to still be elevated screen time among adolescents due to poor habits formed during the pandemic lockdowns. This paper explores the factors by which screen time affects well-being among adolescents and how the pandemic may have influenced some of these factors. For example, beyond having greater screen time, many adolescents have also reduced their physical activities and …
Online Hyperparameter Optimization For Class-Incremental Learning, Yaoyao Liu, Yingying Li, Bernt Schiele, Qianru Sun
Online Hyperparameter Optimization For Class-Incremental Learning, Yaoyao Liu, Yingying Li, Bernt Schiele, Qianru Sun
Research Collection School Of Computing and Information Systems
Class-incremental learning (CIL) aims to train a classification model while the number of classes increases phase-by-phase. An inherent challenge of CIL is the stability-plasticity tradeoff, i.e., CIL models should keep stable to retain old knowledge and keep plastic to absorb new knowledge. However, none of the existing CIL models can achieve the optimal tradeoff in different data-receiving settings—where typically the training-from-half (TFH) setting needs more stability, but the training-from-scratch (TFS) needs more plasticity. To this end, we design an online learning method that can adaptively optimize the tradeoff without knowing the setting as a priori. Specifically, we first introduce the …
Real-Time Hierarchical Map Segmentation For Coordinating Multi-Robot Exploration, Tianze Luo, Zichen Chen, Budhitama Subagdja, Ah-Hwee Tan
Real-Time Hierarchical Map Segmentation For Coordinating Multi-Robot Exploration, Tianze Luo, Zichen Chen, Budhitama Subagdja, Ah-Hwee Tan
Research Collection School Of Computing and Information Systems
Coordinating a team of autonomous agents to explore an environment can be done by partitioning the map of the environment into segments and allocating the segments as targets for the individual agents to visit. However, given an unknown environment, map segmentation must be conducted in a continuous and incremental manner. In this paper, we propose a novel real-time hierarchical map segmentation method for supporting multi-agent exploration of indoor environments, wherein clusters of regions of segments are formed hierarchically from randomly sampled points in the environment. Each cluster is then assigned with a cost-utility value based on the minimum cost possible …
The City Never Sleeps: But When Will Investment Banks Wake Up To The Climate Crisis?, Theodor Florian Cojoianu, Andrea G. F. Hoepner, Fabiola I. Schneider, Michael Urban, Anh Vu, Dariusz Wojcik
The City Never Sleeps: But When Will Investment Banks Wake Up To The Climate Crisis?, Theodor Florian Cojoianu, Andrea G. F. Hoepner, Fabiola I. Schneider, Michael Urban, Anh Vu, Dariusz Wojcik
Research Collection College of Integrative Studies
Using a global dataset of over 840,000 equity, bond and syndicated loan investment banking deals, we build the fossil fuel investment brokerage profile of financial centres worldwide between 2000 and 2018. We also study whether city-level fossil fuel divestment commitments and country-level green banking policies impact the profile of fossil fuel financial centres over our study timeframe. We find that several financial centres shift their fossil fuel investment brokerage profiles substantially, including the asset classes in which they are active. However, we do not find any evidence that this is driven by city-level divestment commitments. In contrast, we find that …
What Are The Relationships Between Public Transit And Gentrification Progress? An Empirical Study In The New York-Northern New Jersey-Long Island Areas, Yefu Chen, Hao Xi, Junfeng Jiao
What Are The Relationships Between Public Transit And Gentrification Progress? An Empirical Study In The New York-Northern New Jersey-Long Island Areas, Yefu Chen, Hao Xi, Junfeng Jiao
Research Collection College of Integrative Studies
Transit-oriented development has been a widely accepted tool among transportation planning practitioners; however, there are concerns about the risk of increasing residential property values leading to gentrification or displacements. Therefore, it is critical to provide precise investigations of the relationships between public transit and gentrification. Although numerous studies have explored this topic, few have discussed these relationships based on detailed measurements of gentrification from a regional perspective. This study aims to fill the research gap by measuring the gentrification subcategories through a hierarchical definition based on data in the New York–Northern New Jersey–Long Island areas and applying the transit desert …
Reconstruction Of Asphalt Pavements With Crumb Rubber Modified Asphalt Mixture In Cold Region: Material Characterization, Construction, And Performance, Dongzhao Jin, Dongdong Ge, Jiaqing Wang, Lance Malburg, Zhanping You
Reconstruction Of Asphalt Pavements With Crumb Rubber Modified Asphalt Mixture In Cold Region: Material Characterization, Construction, And Performance, Dongzhao Jin, Dongdong Ge, Jiaqing Wang, Lance Malburg, Zhanping You
Michigan Tech Publications, Part 1
Dry-processed rubberized asphalt mixture has recently attracted a lot of attention as an alternative to conventional asphalt mixtures. Dry-processed rubberized asphalt pavement has improved the overall performance characteristics compared to the conventional asphalt road. The objective of this research is to demonstrate the reconstruction of rubberized asphalt pavement and evaluate the pavement performance of dry-processed rubberized asphalt mixture based on laboratory and field tests. The noise mitigation effect of dry-processed rubberized asphalt pavement was evaluated at the field construction sites. A prediction of pavement distresses and long-term performance was also conducted using mechanistic-empirical pavement design. In terms of experimental evaluation, …
Noise2clean: Cross-Device Side-Channel Traces Denoising With Unsupervised Deep Learning, Honggang Yu, Mei Wang, Xiyu Song, Haoqi Shan, Hongbing Qiu, Junyi Wang, Kaichen Yang
Noise2clean: Cross-Device Side-Channel Traces Denoising With Unsupervised Deep Learning, Honggang Yu, Mei Wang, Xiyu Song, Haoqi Shan, Hongbing Qiu, Junyi Wang, Kaichen Yang
Michigan Tech Publications, Part 1
Deep learning (DL)-based side-channel analysis (SCA) has posed a severe challenge to the security and privacy of embedded devices. During its execution, an attacker exploits physical SCA leakages collected from profiling devices to create a DL model for recovering secret information from victim devices. Despite this success, recent works have demonstrated that certain countermeasures, such as random delay interrupts or clock jitters, would make these attacks more complex and less practical in real-world scenarios. To address this challenge, we present a novel denoising scheme that exploits the U-Net model to pre-process SCA traces for “noises” (i.e., countermeasures) removal. Specifically, we …
Cascading Effects Of Cover Crops On The Subsequent Cash Crop Defense Against The Polyphagous Herbivore Fall Armyworm (Spodoptera Frugiperda), Adegboyega Fajemisin, Alexis Racelis, Rupesh Kariyat
Cascading Effects Of Cover Crops On The Subsequent Cash Crop Defense Against The Polyphagous Herbivore Fall Armyworm (Spodoptera Frugiperda), Adegboyega Fajemisin, Alexis Racelis, Rupesh Kariyat
Entomology and Plant Pathology Faculty Publications and Presentations
Recent studies have started to show that the benefits of cover crops can cascade to the cash crop growing seasons. However, the impact of cover crops on the subsequent cash crop defense against herbivores is not well understood. To test this, we conducted a field and laboratory study to assess the possible cascading effects of cover crops such as Vigna unguiculata, Sorghum drummondii, Raphanus sativus, and Crotalaria juncea on the subsequent cash crop (Sorghum bicolor) defense against the notorious polyphagous herbivore fall armyworm (Spodoptera frugiperda) across three farms in the Lower Rio Grande Valley. Our field …
Major Questions And An Emergency Question Doctrine: The Biden Student Debt Case Study Of Pretextual Abuse Of Emergency Powers, Jed Handelsman Shugerman
Major Questions And An Emergency Question Doctrine: The Biden Student Debt Case Study Of Pretextual Abuse Of Emergency Powers, Jed Handelsman Shugerman
Faculty Scholarship
The major question doctrine tries to address one problem, the Imperial Executive, by escalating another, the Imperial Judiciary. This article proposes a solution, with the Biden Student Debt Waiver as a case study: An “emergency question” doctrine.
This emergency questions doctrine would apply when the executive relies on a statutory emergency clause or invokes an emergency in its application of a statutory provision. As a matter of statutory interpretation, the emergency question doctrine would follow the two most important steps of the major question approach: 1) relying on purpose and context to clarify and limit the scope of open-ended emergency …
Policing & The Problem Of Physical Restraint, Steven Arrigg Koh
Policing & The Problem Of Physical Restraint, Steven Arrigg Koh
Faculty Scholarship
The Fourth Amendment of the U.S. Constitution prohibits unreasonable “seizures” and thus renders unlawful police use of excessive force. On one hand, this definition is expansive. In the U.S. Supreme Court’s 2021 Term, in Torres v. Madrid, the Court clarified that a “seizure” includes any police application of physical force to the body with intent to restrain. Crucially, Chief Justice Roberts’ majority opinion emphasized that police may seize even when merely laying “the end of a finger” on a layperson’s body. And yet, the Supreme Court’s Fourth Amendment totality-of-the-circumstances reasonableness balancing test is notoriously imprecise—a “factbound morass,” in the famous …
Student Senate Meeting Minutes February 1, 2023, Student Senate-Winona State University
Student Senate Meeting Minutes February 1, 2023, Student Senate-Winona State University
Student Senate Meeting Minutes
This document is the official Winona State University Student Senate Minutes February 1, 2023.
Trauma Presentation Among Latinx/Hispanic Subgroups, Ana Paula Leao De Camargo
Trauma Presentation Among Latinx/Hispanic Subgroups, Ana Paula Leao De Camargo
Theses and Dissertations
Hispanics/Latinos are the fastest-growing minority group in the United States and are estimated to compose half of the American population by 2060 if growing trends follow current levels. It has been suggested that Latinx/Hispanics perceive and react to adverse experiences with somatization, which is highly comorbid with Post-traumatic Stress Disorder (PTSD) symptoms (van der Kolk, et al 1996). This study surveyed 451 participants from which 88% identified as being Hispanic or Latinas, 2.7% identified as being Black Hispanic/Black Latina, and 9.3% identified as having mixed ethnicities including Hispanic/Latina. Regarding place of birth, 431 respondents (95.6%) identified being born in Continental …
Front Matter, Michigan Law Review
Front Matter, Michigan Law Review
Michigan Law Review
Front Matter for Volume 121, Issue 4 of Michigan Law Review
Race-Ing Antitrust, Bennett Capers, Gregory Day
Race-Ing Antitrust, Bennett Capers, Gregory Day
Michigan Law Review
Antitrust law has a race problem. To spot an antitrust violation, courts inquire into whether an act has degraded consumer welfare. Since anticompetitive practices are often assumed to enhance consumer welfare, antitrust offenses are rarely found. Key to this framework is that antitrust treats all consumers monolithically; that consumers are differently situated, especially along lines of race, simply is ignored.
We argue that antitrust law must disaggregate the term “consumer” to include those who disproportionately suffer from anticompetitive practices via a community welfare standard. As a starting point, we demonstrate that anticompetitive conduct has specifically been used as a tool …
Understanding And Improving Older People’S Well-Being Through Social Prescribing Involving The Cultural Sector: Interviews From A Realist Evaluation, Jordan Gorenberg, Stephanie Tierney, Geoff Wong, Amadea Turk, Sebastien Libert, Caroline Potter, Kathryn Eccles, Shona Forster, Kerryn Husk, Helen J. Chatterjee, Emma Webster, Beth Mcdougall, Harriet Warburton, Lucy Shaw, Kamal R. Mahtani
Understanding And Improving Older People’S Well-Being Through Social Prescribing Involving The Cultural Sector: Interviews From A Realist Evaluation, Jordan Gorenberg, Stephanie Tierney, Geoff Wong, Amadea Turk, Sebastien Libert, Caroline Potter, Kathryn Eccles, Shona Forster, Kerryn Husk, Helen J. Chatterjee, Emma Webster, Beth Mcdougall, Harriet Warburton, Lucy Shaw, Kamal R. Mahtani
Peninsula Medical School
Social prescribing is a non-clinical approach to addressing social, environmental, and economic factors affecting how people feel physical and/or emotionally. It involves connecting people to ?community assets? (e.g., local groups, organizations, and charities) that can contribute to positive well-being. We sought to explain in what ways, for whom, and why the cultural sector can support social prescribing with older people. We conducted semi-structured interviews with 28 older people (aged 60+) and 25 cultural sector staff. The following nine concepts, developed from interview data, progressed the understanding of tailoring cultural offers, which came from our previous realist review?immersion, buddying, café culture, …
Using Digital Technologies To Facilitate Social Inclusion During The Covid‐19 Pandemic: Experiences Of Co‐Resident And Non‐Co‐Resident Family Carers Of People With Dementia From Determind‐C19, B Hicks, Determind Team
Using Digital Technologies To Facilitate Social Inclusion During The Covid‐19 Pandemic: Experiences Of Co‐Resident And Non‐Co‐Resident Family Carers Of People With Dementia From Determind‐C19, B Hicks, Determind Team
Peninsula Medical School
Background The COVID-19 pandemic triggered rapid and unprecedented changes in the use of digital technologies to support people's social inclusion. We examined whether and how co-resident and non-co-resident family carers of people with dementia engaged with digital technologies during this period. Methods Throughout November 2020-February 2021, we interviewed 42 family carers of people with dementia from our DETERMIND-C19 cohort. Preliminary analysis was conducted through Framework analysis, followed by an inductive thematic analysis. Findings Digital technologies served as a Facilitator for social inclusion by enabling carers to counter the effects of the differing restrictions imposed on them so they could remain …
Digital Twin Applications In 3d Concrete Printing, Yuxin Wang, Farhad Aslani, Arcady Dyskin, Elena Pasternak
Digital Twin Applications In 3d Concrete Printing, Yuxin Wang, Farhad Aslani, Arcady Dyskin, Elena Pasternak
Research outputs 2022 to 2026
The benefits of 3D concrete printing (3DCP) include reducing construction time and costs, providing design freedom, and being environmentally friendly. This technology is expected to be effective in addressing the global house shortage. This review highlights the main 3DCP applications and four critical challenges. It is proposed to combine 3D concrete printing with Digital Twin (DT) technology to meet the challenges the 3DCP faces and improve quality and sustainability. This paper provides a critical review of research into the application of DT technology in 3DCP, categorize the applications and directions proposed according to different lifecycles, and explore the possibility of …
Epigenetic Regulation Of Corneal Epithelial Differentiation By Tet2, Yuzuru Sasamoto, Siyuan Wu, Catherine A. A. Lee, Jason Y. Jiang, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank
Epigenetic Regulation Of Corneal Epithelial Differentiation By Tet2, Yuzuru Sasamoto, Siyuan Wu, Catherine A. A. Lee, Jason Y. Jiang, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank
Research outputs 2022 to 2026
Epigenetic DNA modification by 5-hydroxymethylcytosine (5hmC), generated by the Ten-eleven translocation (TET) dioxygenases, regulates diverse biological functions in many organ tissues, including the mammalian eye. For example, 5hmC has been shown to be involved in epigenetic regulation of retinal gene expression. However, a functional role of 5hmC in corneal differentiation has not been investigated to date. Here, we examined 5hmC and TET function in the human cornea. We found 5hmC highly expressed in MUC16-positive terminally differentiated cells that also co-expressed the 5hmC-generating enzyme TET2. TET2 knockdown (KD) in cultured corneal epithelial cells led to significant reductions of 5hmC peak distributions …
Exploring Sociodemographic Correlates Of Suicide Stigma In Australia: Baseline Cross-Sectional Survey Findings From The Life-Span Suicide Prevention Trial Studies, Lisa N. Sharwood, Alison L. Calear, Philip J. Batterham, Michelle Torok, Lauren Mcgillivray, Demee Rheinberger, Stephanie Zeritis, Tuguy Esgin, Fiona Shand
Exploring Sociodemographic Correlates Of Suicide Stigma In Australia: Baseline Cross-Sectional Survey Findings From The Life-Span Suicide Prevention Trial Studies, Lisa N. Sharwood, Alison L. Calear, Philip J. Batterham, Michelle Torok, Lauren Mcgillivray, Demee Rheinberger, Stephanie Zeritis, Tuguy Esgin, Fiona Shand
Research outputs 2022 to 2026
The risk of suicidal behaviour in Australia varies by age, sex, sexual preference and Indigenous status. Suicide stigma is known to affect suicide rates and help-seeking for suicidal crises. The aim of this study was to investigate the sociodemographic correlates of suicide stigma to assist in prevention efforts. We surveyed community members and individuals who had attended specific emergency departments for suicidal crisis. The respondents were part of a large-scale suicide prevention trial in New South Wales, Australia. The data collected included demographic characteristics, measures of help-seeking and suicide stigma. The linear regression analyses conducted sought to identify the factors …
A Computational Offloading Optimization Scheme Based On Deep Reinforcement Learning In Perceptual Network, Yongli Xing, Tao Ye, Sami Ullah, Muhammad Waqas, Hisham Alasmary, Zihui Liu
A Computational Offloading Optimization Scheme Based On Deep Reinforcement Learning In Perceptual Network, Yongli Xing, Tao Ye, Sami Ullah, Muhammad Waqas, Hisham Alasmary, Zihui Liu
Research outputs 2022 to 2026
Currently, the deep integration of the Internet of Things (IoT) and edge computing has improved the computing capability of the IoT perception layer. Existing offloading techniques for edge computing suffer from the single problem of solidifying offloading policies. Based on this, combined with the characteristics of deep reinforcement learning, this paper investigates a computation offloading optimization scheme for the perception layer. The algorithm can adaptively adjust the computational task offloading policy of IoT terminals according to the network changes in the perception layer. Experiments show that the algorithm effectively improves the operational efficiency of the IoT perceptual layer and reduces …
Citation Impact And Reach Of The Ioc Sport And Exercise Medicine Consensus Statements, Lauren V. Fortington, Rebecca N. Handcock, Wayne Derman, Carolyn A. Emery, Kati Pasanen, Martin Schwellnus, Evert Verhagen, Caroline F. Finch
Citation Impact And Reach Of The Ioc Sport And Exercise Medicine Consensus Statements, Lauren V. Fortington, Rebecca N. Handcock, Wayne Derman, Carolyn A. Emery, Kati Pasanen, Martin Schwellnus, Evert Verhagen, Caroline F. Finch
Research outputs 2022 to 2026
Background: Research evidence is commonly compiled into expert-agreed consensus statements or guidelines, with an increasing trend towards their publication in peer-reviewed journals. Prominent among these has been the publication of several International Olympic Committee (IOC) tatements to help inform sport and exercise medicine (SEM) practice. This study aimed to assess the citation impact and reach of the IOC statements published between 2003 and 2020. Method: Bibliometric analysis focused on identifying core publications (original statement and linked publications) and quantifying their academic citations (number and Field-Weighted Citation Impact (FWCI)) in journal articles up to February 2022. The analysis includes descriptive data …
Editorial: Untangle The Broad Connections And Tight Interactions Between Human Microbiota And Complex Diseases Through Data-Driven Approaches, Liang Wang, Zuo-Bin Zhu, Li Zhang, Jian Li, Qi Zhao
Editorial: Untangle The Broad Connections And Tight Interactions Between Human Microbiota And Complex Diseases Through Data-Driven Approaches, Liang Wang, Zuo-Bin Zhu, Li Zhang, Jian Li, Qi Zhao
Research outputs 2022 to 2026
It is well-known that microorganisms are ubiquitous in the environment and occupy almost all habitats in animals and humans (Finlay and Clarke, 1999; Rosenberg, 2021). Traditionally, microorganisms are studied as individuals grown in isolation under artificial conditions; however, with the development of experimental techniques and computational methods, microbes are now frequently considered as a functional group in a particular niche and studied at the community level in order to best mimicking the real-world situations (American Academy of Microbiology, 2004). During the study of microbial communities, two terms are commonly used, that is, microbiota and microbiome.
Impact Of The Skill Shortage On The Construction Supply Chain Performance In Australia, Ming Juan Ding, Ferry Jie, Sommala Sisombat, Bala S. Bandlamudi
Impact Of The Skill Shortage On The Construction Supply Chain Performance In Australia, Ming Juan Ding, Ferry Jie, Sommala Sisombat, Bala S. Bandlamudi
Research outputs 2022 to 2026
The purpose of this paper is to investigate how the skill shortage impacts the performance of the construction supply chain in Australia. The study has adopted a quantitative research method. The quantitative data were collected by conducting a survey of employees who work in construction companies in Australia. A regression analysis was used to analyze the data from 113 respondents. The findings of the study reveal that the construction sector in Australia has high labour costs, but workers are still thinking they are not getting paid enough and cannot invest more in themselves to improve their skills. There is a …
Validity And Reliability Of Inertial Measurement System For Linear Movement Velocity In Flywheel Squat Exercise, Sergio Maroto-Izquierdo, Kazunori Nosaka, Jesús Alarcón-Gómez, Fernando Martín-Rivera
Validity And Reliability Of Inertial Measurement System For Linear Movement Velocity In Flywheel Squat Exercise, Sergio Maroto-Izquierdo, Kazunori Nosaka, Jesús Alarcón-Gómez, Fernando Martín-Rivera
Research outputs 2022 to 2026
The aim of this study was to examine the validity and reliability of an Inertial Measurement System integrated into a secondary pulley (IMS) for determining linear velocity during flywheel squat exercises. Thirty-one male participants who were highly experienced in a flywheel resistance exercise training performed flywheel squat exercises with three incremental loads, and mean velocity (MV), mean propulsive velocity (MPV) and max velocity (Vmax) of the exercises were simultaneously recorded with a validated linear encoder and the IMS, in two different sessions. Validity was analyzed using ordinary least products regression (OLP), Lin’s concordance correlation coefficient (CCC), and Hedge’s g for …
Final Results From A Phase 2b Randomized, Placebo-Controlled Clinical Trial Of Rbx2660: A Microbiota-Based Drug For The Prevention Of Recurrent Clostridioides Difficile Infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, Christine Lee
Final Results From A Phase 2b Randomized, Placebo-Controlled Clinical Trial Of Rbx2660: A Microbiota-Based Drug For The Prevention Of Recurrent Clostridioides Difficile Infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, Christine Lee
2020-Current year OA Pubs
INTRODUCTION: Effective treatments for recurrent Clostridioides difficile infection (rCDI) are urgently needed. RBX2660 is an investigational microbiota-based live biotherapeutic to reduce CDI recurrence following standard-of-care antibiotic treatment in individuals with rCDI. Here we report the final safety data through 24 months of follow-up as well as final efficacy data, reflecting alignment of the pre-specified statistical analysis plan definitions with the data presented.
METHODS: The PUNCH CD2 clinical trial was a prospective, multicenter, randomized, double-blinded, placebo-controlled, three-arm phase 2b study conducted to evaluate the efficacy and safety of RBX2660 for the reduction of rCDI compared to placebo. Eligible patients were at …
Ubs In The World: 1929–1934, Union Bank Of Switzerland (Ubs)
Ubs In The World: 1929–1934, Union Bank Of Switzerland (Ubs)
Documents
No abstract provided.
A Simple Point-Of-Care Assay Accurately Detects Anti-Spike Antibodies After Sars-Cov-2 Vaccination, Sarah E Greene, Yuefang Huang, Wooseob Kim, Mariel J Liebeskind, Vinay Chandrasekaran, Zhuoming Liu, Parakkal Deepak, Michael A Paley, Daphne Lew, Mary C Nakamura, Jane A O'Hallaran, Rachel M Presti, Sean P J Whelan, William J Buchser, Alfred H J Kim, Gary J Weil, Et Al.
A Simple Point-Of-Care Assay Accurately Detects Anti-Spike Antibodies After Sars-Cov-2 Vaccination, Sarah E Greene, Yuefang Huang, Wooseob Kim, Mariel J Liebeskind, Vinay Chandrasekaran, Zhuoming Liu, Parakkal Deepak, Michael A Paley, Daphne Lew, Mary C Nakamura, Jane A O'Hallaran, Rachel M Presti, Sean P J Whelan, William J Buchser, Alfred H J Kim, Gary J Weil, Et Al.
2020-Current year OA Pubs
OBJECTIVE: Lateral flow assays (LFA) are sensitive for detecting antibodies to SARS-CoV-2 proteins within weeks after infection. This study tested samples from immunocompetent adults, and those receiving treatments for chronic inflammatory diseases (CID), before and after mRNA SARS-CoV-2 vaccination.
METHODS: We compared results obtained with the COVIBLOCK Covid-19 LFA to those obtained by anti-spike (S) ELISA.
RESULTS: The LFA detected anti-S antibodies in 29 of 29 (100%) of the immunocompetent and 110 of 126 (87.3%) of the CID participants after vaccination. Semiquantitative LFA scores were statistically significantly lower in samples from immunosuppressed participants, and were significantly correlated with anti-S antibody …