Digital Commons Network^™

Autophagy Requirements For Eye Lens Differentiation And Transparency, Lisa Brennan, M Joseph Costello, J Fielding Hejtmancik, A. Menko, S Amer Riazuddin, Alan Shiels, Marc Kantorow

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Recent evidence points to autophagy as an essential cellular requirement for achieving the mature structure, homeostasis, and transparency of the lens. Collective evidence from multiple laboratories using chick, mouse, primate, and human model systems provides evidence that classic autophagy structures, ranging from double-membrane autophagosomes to single-membrane autolysosomes, are found throughout the lens in both undifferentiated lens epithelial cells and maturing lens fiber cells. Recently, key autophagy signaling pathways have been identified to initiate critical steps in the lens differentiation program, including the elimination of organelles to form the core lens organelle-free zone. Other recent studies using ex vivo lens culture …

Neur 491.02: Neurolinguistics, Danielle K. Fahey

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Slp 694.01: Phd Graduate Seminar, Catherine A. Off

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Muse 127.01: Techniques - Percussion Instruments In Class Ii, Robert Ledbetter

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Fors 320.01: Forest And Resource Economics, Robert J, Sonora

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Fors 540.01: Disturbance Ecology, Philip Higuera

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Fors 350.00: Forestry Applications Of Gis, Kevin G. Mcmanigal

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Hstr 291.80: Seminar For Terrorism In The Modern World - Honors, Richard Drake

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Wild 472.01: Wildlife Handling And Chemical Immobilization For Wildlife Professionals, Mark R. Johnson

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Robotic And Navigated Pedicle Screws Are Safer And More Accurate Than Fluoroscopic Freehand Screws: A Systematic Review And Meta-Analysis, Abhijith V. Matur, Paolo Palmisciano, Henry Ofori Duah, Sai S. Chilakapati, Joseph S. Cheng, Owoicho Adogwa

College of Nursing Faculty Research and Publications

BACKGROUND CONTEXT

Navigated and robotic pedicle screw placement systems have been developed to improve the accuracy of screw placement. However, the literature comparing the safety and accuracy of robotic and navigated screw placement with fluoroscopic freehand screw placement in thoracolumbar spine surgery has been limited.

PURPOSE

To perform a systematic review and meta-analysis of randomized control trials that compared the accuracy and safety profiles of robotic and navigated pedicle screws with fluoroscopic freehand pedicle screws.

STUDY DESIGN/SETTING

Systematic review and meta-analysis

PATIENT SAMPLE

Only randomized controlled trials comparing robotic-assisted or navigated pedicle screws placement with freehand pedicle screw placement in …

Patient-Mediated Interventions In Hospital: A Systematic Review, Georgia Tobiano, Shelley Roberts, Rachel Muir, Teresa Jerofke-Owen, Christine Ting, Sarah Thorning, Daren K. Heyland, Andrea P. Marshall

College of Nursing Faculty Research and Publications

Aims

To describe the characteristics of hospital-based, patient-mediated interventions and their impact on patient, clinician and organization outcomes.

Design

Systematic review.

Data Sources

Health literature databases (MEDLINE, CINAHL and EMBASE) were searched in August 2021. Backward and forward citation searching was conducted.

Review Methods

Studies investigating patient-mediated interventions, targeted at adult hospitalized patients were eligible. Data were extracted related to study and intervention characteristics. Narrative synthesis was used to understand intervention impact on patient, clinician and organization outcomes (as per a framework). Methodological quality was assessed using the Mixed Methods Assessment Tool.

Results

Thirty-three studies, reporting 18 interventions, were included. …

Genomic Underpinnings Of Population Persistence In Isle Royale Moose, Christopher C. Kyriazis, Annabel C. Beichman, Kristin Brzeski, Sarah Hoy, Rolf O. Peterson, John A. Vucetich, Leah Vucetich, Kirk E. Lohmueller, Robert K. Wayne

Michigan Tech Publications, Part 1

Island ecosystems provide natural laboratories to assess the impacts of isolation on population persistence. However, most studies of persistence have focused on a single species, without comparisons to other organisms they interact with in the ecosystem. The case study of moose and gray wolves on Isle Royale allows for a direct contrast of genetic variation in isolated populations that have experienced dramatically differing population trajectories over the past decade. Whereas the Isle Royale wolf population recently declined nearly to extinction due to severe inbreeding depression, the moose population has thrived and continues to persist, despite having low genetic diversity and …

Selectively Modified Lactose And N-Acetyllactosamine Analogs At Three Key Positions To Afford Effective Galectin-3 Ligands †, Shuay Abdullayev, Priyanka Dipak Kadav, Purnima Bandyopadhyay, Francisco Javier Medrano, Gabriel A. Rabinovich, Tarun K. Dam, Antonio Romero, René Roy

Michigan Tech Publications, Part 1

Galectins constitute a family of galactose-binding lectins overly expressed in the tumor microenvironment as well as in innate and adaptive immune cells, in inflammatory diseases. Lactose ((β-D-galactopyranosyl)-(1→4)-β-D-glucopyranose, Lac) and N-Acetyllactosamine (2-acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LacNAc) have been widely exploited as ligands for a wide range of galectins, sometimes with modest selectivity. Even though several chemical modifications at single positions of the sugar rings have been applied to these ligands, very few examples combined the simultaneous modifications at key positions known to increase both affinity and selectivity. We report herein combined modifications at the anomeric position, C-2, and O-3′ of each of the two …

A Catalog Of The Highest-Energy Cosmic Rays Recorded During Phase I Of Operation Of The Pierre Auger Observatory, A. Abdul Halim, P. Abreu, M. Aglietta, I. Allekotte, P. Allison, K. Almeida Cheminant, J. Chirinos, B. Fick, D. Nitz, I. Norwood, A. Puyleart, Et Al.

Michigan Tech Publications, Part 1

A catalog containing details of the highest-energy cosmic rays recorded through the detection of extensive air showers at the Pierre Auger Observatory is presented with the aim of opening the data to detailed examination. Descriptions of the 100 showers created by the highest-energy particles recorded between 2004 January 1 and 2020 December 31 are given for cosmic rays that have energies in the range 78-166 EeV. Details are also given on a further nine very energetic events that have been used in the calibration procedure adopted to determine the energy of each primary. A sky plot of the arrival directions …

Utilization Of Mechanically Recycled Carbon Fibers In Vinyl Ester Composites, Khaled Alharmoodi, Amir Hussain Idrisi, Abdel Hamid Ismail Mourad, Basim Abu-Jdayil

Michigan Tech Publications, Part 1

As we enter the twenty-first century, the aviation sector is expected to thrive as flying becomes the primary mode of transportation between states or nations. With such a demand, there is a corresponding need to manufacture aircraft components. The study focused on recycling carbon fiber composites received from the STRATA company, which were cut-off/waste material generated during the manufacture of airplane components. The cut-offs were then reduced to powder form using a standard face milling machine in three sizes (90, 150, and 250 µm). After, the powder was utilized to fabricate vinyl ester composites with four weight percentages (10%, 20%, …

The Genetic Mechanisms Underlying The Concerted Expression Of The Yellow And Tan Genes In Complex Patterns On The Abdomen And Wings Of Drosophila Guttifera, Komal K.B. Raja, Evan A. Bachman, Catrina E. Fernholz, David S. Trine, Rebecca E. Hobmeier, Nathaniel J. Maki, Timothy J. Massoglia, Thomas Werner

Michigan Tech Publications, Part 1

How complex morphological patterns form is an intriguing question in developmental biology. However, the mechanisms that generate complex patterns remain largely unknown. Here, we sought to identify the genetic mechanisms that regulate the tan (t) gene in a multi-spotted pigmentation pattern on the abdomen and wings of Drosophila guttifera. Previously, we showed that yellow (y) gene expression completely prefigures the abdominal and wing pigment patterns of this species. In the current study, we demonstrate that the t gene is co-expressed with the y gene in nearly identical patterns, both transcripts foreshadowing the adult abdominal and wing melanin spot patterns. We …

Wildfire Risk Zone Mapping In Contrasting Climatic Conditions: An Approach Employing Ahp And F-Ahp Models, Aishwarya Sinha, Suresh Nikhil, Rajendran Shobha Ajin, Jean Homian Danumah, Sunil Saha, Romulus Costache, Ambujendran Rajaneesh, Kochappi Sathyan Sajinkumar, Kolangad Amrutha, Alfred Johny, Fahad Marzook, Pratheesh Chacko Mammen, Kamal Abdelrahman, Mohammed S. Fnais, Mohamed Abioui

Michigan Tech Publications, Part 1

Wildfires are one of the gravest and most momentous hazards affecting rich forest biomes worldwide; India is one of the hotspots due to its diverse forest types and human-induced reasons. This research aims to identify wildfire risk zones in two contrasting climate zones, the Wayanad Wildlife Sanctuary in the Western Ghats and the Kedarnath Wildlife Sanctuary in the Himalayas, using geospatial tools, analytical hierarchy process (AHP), and fuzzy-AHP models to assess the impacts of various conditioning factors and compare the efficacy of the two models. Both of the wildlife sanctuaries were severely battered by fires in the past, with more …

Noise2clean: Cross-Device Side-Channel Traces Denoising With Unsupervised Deep Learning, Honggang Yu, Mei Wang, Xiyu Song, Haoqi Shan, Hongbing Qiu, Junyi Wang, Kaichen Yang

Michigan Tech Publications, Part 1

Deep learning (DL)-based side-channel analysis (SCA) has posed a severe challenge to the security and privacy of embedded devices. During its execution, an attacker exploits physical SCA leakages collected from profiling devices to create a DL model for recovering secret information from victim devices. Despite this success, recent works have demonstrated that certain countermeasures, such as random delay interrupts or clock jitters, would make these attacks more complex and less practical in real-world scenarios. To address this challenge, we present a novel denoising scheme that exploits the U-Net model to pre-process SCA traces for “noises” (i.e., countermeasures) removal. Specifically, we …

The Phangs-Jwst Treasury Survey: Star Formation, Feedback, And Dust Physics At High Angular Resolution In Nearby Galaxies, Janice C. Lee, Karin M. Sandstrom, Adam K. Leroy, David A. Thilker, Eva Schinnerer, Erik Rosolowsky, Judy Schmidt, Et Al.

Michigan Tech Publications, Part 1

The PHANGS collaboration has been building a reference data set for the multiscale, multiphase study of star formation and the interstellar medium (ISM) in nearby galaxies. With the successful launch and commissioning of JWST, we can now obtain high-resolution infrared imaging to probe the youngest stellar populations and dust emission on the scales of star clusters and molecular clouds (∼5-50 pc). In Cycle 1, PHANGS is conducting an eight-band imaging survey from 2 to 21 μm of 19 nearby spiral galaxies. Optical integral field spectroscopy, CO(2-1) mapping, and UV-optical imaging for all 19 galaxies have been obtained through large programs …

Dsrc Versus Lte-V2x: Empirical Performance Analysis Of Direct Vehicular Communication Technologies, Ehsan Moradi-Pari, Danyang Tian, Mojtaba Bahramgiri, Samer Rajab, Sue Bai

Michigan Tech Publications, Part 1

Vehicle-to-Vehicle (V2V) communication systems have an eminence potential to improve road safety and optimize traffic flow by broadcasting Basic Safety Messages (BSMs). Dedicated Short-Range Communication (DSRC) and LTE Vehicle-to-Everything (V2X) are two candidate technologies to enable V2V communication. DSRC relies on the IEEE 802.11p standard for its PHY and MAC layer while LTE-V2X is based on 3GPP’s Release 14 and operates in a distributed manner in the absence of cellular infrastructure. There has been considerable debate over the relative advantages and disadvantages of DSRC and LTE-V2X, aiming to answer the fundamental question of which technology is most effective in real-world …

Attitudes, Clinical Practices, And Perceived Advocacy Needs Of Professionals With Interests In Personality Disorders, William D. Ellison, S. Huprich, A. Behn, M. Goodman, S. Kerr, K. N. Levy, S. M. Nelson, C. Sharp, The Board Of Directors Of The International Society For The Study Of Personality Disorders

Psychology Faculty Research

Experts in personality disorders (PDs) generally prefer dimensional diagnostic systems to categorical ones, but less is known about experts’ attitudes toward personality pathology diagnoses in adolescents, and little is known about public health shortfalls and advocacy needs and how these might differ geographically. To fill these gaps, the International Society for the Study of Personality Disorders surveyed 248 professionals with interests in PDs about their attitudes toward different diagnostic systems for adults and adolescents, their PD-related clinical practices, and perceived advocacy needs in their area. Results suggested that dimensional diagnostic systems are preferable to categorical and that skepticism about personality …

Laser Powder Bed Fusion Of Molybdenum And Mo-0.1sic Studied By Positron Annihilation Lifetime Spectroscopy And Electron Backscatter Diffraction Method, Nathan E. Ellsworth, Joshua R. Machacek, Ryan A. Kemnitz, Cayla C. Eckley, Brianna M. Sexton, Joel S. Gearhart, Larry W. Burggraf

Faculty Publications

Positron annihilation lifetime spectroscopy (PALS) has been used for the first time to investigate the microstructure of additively manufactured molybdenum. Despite the wide applicability of positron annihilation spectroscopy techniques to the defect analysis of metals, they have only been used sparingly to monitor the microstructural evolution of additively manufactured metals. Molybdenum and molybdenum with a dilute addition (0.1 wt%) of nano-sized silicon carbide, prepared via laser powder bed fusion (LPBF) at four different scan speeds: 100, 200, 400, and 800 mm/s, were studied by PALS and compared with electron backscatter diffraction analysis. The aim of this study was to clarify …

How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu

Children’s Nutrition Research Center Staff Publications

Background: eHealth interventions using active video games (AVGs) offer an alternative method to help children exercise, especially during a pandemic where options are limited. There is limited data on costs associated with developing and implementing such interventions.

Objectives: We quantified the costs of delivering an eHealth RCT intervention among minority children during COVID-19.

Methods: We categorized the total trial cost into five subcategories: intervention material development, advertising and recruitment, intervention delivery, personnel salaries, and COVID-19-related equipment costs.

Results: The total RCT cost was $1,927,807 (Direct: $1,227,903; Indirect: $699,904) with three visits required for each participant. The average cost per participant …

The Effects Of Robot Voices And Appearances On Users' Emotion Recognition And Subjective Perception, Sangjin Ko, Jaclyn A. Barnes, Jiayuan Dong, Chung Hyuk Park, Ayanna Howard, Myounghoon Jeon

Michigan Tech Publications, Part 1

As the influence of social robots in people's daily lives grows, research on understanding people's perception of robots including sociability, trust, acceptance, and preference becomes more pervasive. Research has considered visual, vocal, or tactile cues to express robots' emotions, whereas little research has provided a holistic view in examining the interactions among different factors influencing emotion perception. We investigated multiple facets of user perception on robots during a conversational task by varying the robots' voice types, appearances, and emotions. In our experiment, 20 participants interacted with two robots having four different voice types. While participants were reading fairy tales to …

Steering Particles Via Micro-Actuation Of Chemical Gradients Using Model Predictive Control, Mark N. Mcdonald, Cameron K. Peterson, Douglas R. Tree

Faculty Publications

Biological systems rely on chemical gradients to direct motion through both chemotaxis and signaling, but synthetic approaches for doing the same are still relatively naïve. Consequently, we present a novel method for using chemical gradients to manipulate the position and velocity of colloidal particles in a microfluidic device. Specifically, we show that a set of spatially localized chemical reactions that are sufficiently controllable can be used to steer colloidal particles via diffusiophoresis along an arbitrary trajectory. To accomplish this, we develop a control method for steering colloidal particles with chemical gradients using nonlinear model predictive control with a model based …

An Overview Of The Republican Party After The 2022 Midterm Elections, Michael Espinoza

Political Science Faculty Publications

Key Takeaways

• The supposed red wave ended up being a red trickle – a missed opportunity but not a complete failure.
• The opportunity for a sizeable swing to the right went unfulfilled – but the Republican Party still won a narrow House majority.
• Trump backed Senate candidates cost the Republican Party a Senate majority.
• The Republican Party still grapples with the Trump dilemma; however, moving on from Trump would not be easy, nor would it signal change within the Republican Party, ‘Make America Great Again’ cultural conservatism took hold of the party before Trump – it merely went by another …

Fecal Elastase In Preterm Infants To Predict Growth Outcomes, Lindsay F Holzapfel, Amy B Hair, Geoffrey A Preidis, Tripti Halder, Heeju Yang, Jana P Unger, Steven Freedman, Camilia R Martin

Faculty, Staff and Student Publications

OBJECTIVES: Preterm infants are born functionally pancreatic insufficient with decreased pancreatic production of lipase and proteases. Developmental pancreatic insufficiency (PI) may contribute to reduced nutrient absorption and growth failure. We sought to determine longitudinal fecal elastase (ELA1) levels in a cohort of preterm infants and whether levels are associated with growth outcomes.

METHODS: Prospective observational study of 30 infants 24-34 weeks gestational age and birth weight ≤1250 g fed the exclusive human milk diet, consisting of human milk with human milk-based fortifier. ELA1 was quantified by ELISA during the first 2 weeks of life [Early; 7.5 ± 1.8 days of …

Rationale And Design Of The Proactive-Hf Trial For Managing Patients With Nyha Class Iii Heart Failure By Using The Combined Cordella Pulmonary Artery Sensor And The Cordella Heart Failure System, Sandra Chaparro

All Publications

Background: Optimizing guideline-directed medical therapy (GDMT) and monitoring congestion in patients with heart failure (HF) are key to disease management and preventing hospitalizations. A pulmonary artery pressure (PAP)-guided HF management system providing access to body weight, blood pressure, heart rate, blood oxygen saturation, PAP, and symptoms, may provide new insights into the effects of patient engagement and comprehensive care for remote GDMT titration and congestion management.

Methods: The PROACTIVE-HF study was originally approved in 2018 as a prospective, randomized, controlled, single-blind, multicenter trial to evaluate the safety and effectiveness of the Cordella PAP Sensor in patients with HF and with …

Randomized Controlled Trial Of A Novel Lifestyle Intervention Used With Or Without Meal Replacements In Work Sites, Sai Krupa Das, Rachel E Silver, Taylor A Vail, Meghan K Chin, Caroline M Blanchard, Stephanie L Dickinson, Xiwei Chen, Lisa Ceglia, Edward Saltzman, David B Allison, Susan B Roberts

Children’s Nutrition Research Center Staff Publications

Objective: Lifestyle interventions have had limited effectiveness in work sites when evaluated in randomized trials. This study assessed the effectiveness of a novel lifestyle intervention for weight loss (Healthy Weight for Living [HWL]) implemented with or without meal replacements (MR) in work sites. HWL used a new behavioral approach emphasizing reducing hunger and building healthy food preferences, and, unlike traditional lifestyle interventions, it did not require calorie counting.

Methods: Twelve work sites were randomized to an 18-month intervention (n = 8; randomization within work sites to HWL, HWL + MR) or 6-month wait-listed control (n = 4). Participants were employees …

Diabetes Of Unclear Type In An Adolescent Boy With Multiple Islet-Cell Autoantibody Positivity Successfully Managed With Glucagon-Like Peptide-1 Receptor Agonist Alone: A Case Report, Olivia Z B Ginnard, Maria J Redondo, Sarah K Lyons

Children’s Nutrition Research Center Staff Publications

Diabetes classification has traditionally considered type 1 and type 2 diabetes as 2 separate entities with different pathogenic mechanisms. However, clinicians and researchers see increasingly more exceptions to this conventional paradigm, leading to a concept of mixed phenotypes in diabetes classification. Herein we report the case of an adolescent with unclear diabetes type due to the presence of obesity, robust endogenous insulin production, multiple islet autoantibody positivity and severe hyperglycemia at diabetes diagnosis that has been successfully treated with liraglutide therapy alone. Our case report highlights the difficulty of diabetes classification and subsequent need for personalized medicine with regard to …