Digital Commons Network^™

A Dlg1-Arhgap31-Cdc42 Axis Is Essential For The Intestinal Stem Cell Response To Fluctuating Niche Wnt Signaling, David Castillo-Azofeifa, Tomas Wald, Efren A Reyes, Aaron Gallagher, Julia Schanin, Stephanie Vlachos, Nathalie Lamarche-Vane, Carolyn Bomidi, Sarah Blutt, Mary K Estes, Todd Nystul, Ophir D Klein

Faculty, Staff and Students Publications

A central factor in the maintenance of tissue integrity is the response of stem cells to variations in the levels of niche signals. In the gut, intestinal stem cells (ISCs) depend on Wnt ligands for self-renewal and proliferation. Transient increases in Wnt signaling promote regeneration after injury or in inflammatory bowel diseases, whereas constitutive activation of this pathway leads to colorectal cancer. Here, we report that Discs large 1 (Dlg1), although dispensable for polarity and cellular turnover during intestinal homeostasis, is required for ISC survival in the context of increased Wnt signaling. RNA sequencing (RNA-seq) and genetic mouse models demonstrated …

Presence Of Trans-Fatty Acids Containing Ingredients In Pre-Packaged Foods And The Availability Of Reported Trans-Fat Levels In Kenya And Nigeria, Liping Huang, Adedayo E Ojo, Judith Kimiywe, Alex Kibet, Boni M Ale, Clementina E Okoro, Jimmy Louie, Fraser Taylor, Mark D Huffman, Dike B Ojji, Jason H Y Wu, Matti Marklund

2020-Current year OA Pubs

In most African countries, the prevalence of industrially produced

Pre-Schoolers’ Images, Intergroup Attitudes, And Liking Of Refugee Peers In Germany, Iris Würbel, Patricia Kanngiesser

School of Psychology

There is extensive research on children’s intergroup attitudes, but their perceptions of refugee children have rarely been studied. We conducted a study with 5- and 6-year-old children (N = 60) in Germany following the arrival of unprecedented large numbers of refugees in 2015 and 2016. Children completed a set of three tasks that measured their perceptions of refugee children (minority group) and German children (majority group): a draw-a-typical-child task (including questions about whether participants wanted to interact with the depicted child), an intergroup attitude task, and a liking task. Results indicate that participants drew similar pictures of and had similar …

Diagnostic Performance Of Screening Tools For Depressive Symptoms In Vulnerable Older Patients With Cancer Undergoing Comprehensive Geriatric Assessment (Cga): Results From The Screen Pilot Study, Laura Tack, Ann Sophie Maenhoudt, Lore Ketelaars, Zutter J De, Stefanie Pinson, Laura Keunebrock, Lorenz Haaker, Kathleen Deckmyn, Mathilde Gheysen, Cindy Kenis, Hans Wildiers, Laurence Depoorter, Pieter Jan Geerts, Rebecca Chandler, Tom Boterberg, Patricia Schofield, Christopher N. Parris, Philip R. Debruyne

School of Nursing and Midwifery

Depression is a common and disabling disorder in later life, particularly among people with poor physical health. There are many screening tools available that can be used to examine depressive symptoms; however, not all of them may be appropriate or accurate for older adults with cancer. This pilot study was designed to test the diagnostic performance of two screening tools and their short versions in a cohort of vulnerable (G8 score ≤ 14/17) older patients with cancer undergoing comprehensive geriatric assessment (CGA). The prospective analysis covered 50 vulnerable patients with cancer aged ≥70 years. The diagnostic performance of the Geriatric …

The Kraft Heinz Company Global Nutrition Targets For The Innovation And Reformulation Of Food And Beverages: Current And Future Directions, Lynn Yu, Véronique Braesco, Sheri L. Cooper, Adam Drewnowski, Bridget Hannon Esteves, Andrea Luigi Budelli

Research outputs 2022 to 2026

Reformulating packaged foods has the potential to improve the nutrient density of the global diet. The present perspective illustrates The Kraft Heinz Company’s approach to product (re)formulation to develop healthier product lines that are lower in saturated fats, total sugars, and sodium, and contain health promoting components. Here we present the rationale for The Kraft Heinz Company’s global nutrition targets used for the global innovation and renovation of foods and beverages. The global nutrition targets use a category specific approach to set maximum levels for the main nutrients of public health concern: saturated fat, total sugars and sodium, taking into …

Between Heaven And Earth! A Poem-Collage Pair About Hypatia Of Alexandria, Sarah Glaz, Mark Sanders

Journal of Humanistic Mathematics

The poem-collage pair presented here is a work of collaboration between the mathematician and poet, Sarah Glaz, and the collage and ceramic artist, Mark Sanders. The piece is part of their larger joint poem-collage project involving the history of mathematics. Included as background is a brief discussion on the history and mathematics involved, and a reflection on several landmark locations and some of the relevant imagery appearing in the poem and the collage.

The Babelogic Of Mathematics, Vijay Fafat

Journal of Humanistic Mathematics

How would the Bible written about a Mathematical God start, describing the Creation of Mathematics and Logic? How would Rigveda's "Nasadiya sukta" read if it were describing the Void before mathematics was "born"? Here is an attempt at a partial answer, one which takes the original Genesis chapter and the Nasadiya sukta and makes suitable changes to create a fairly consistent, if somewhat anachronistic narrative (with the slight mixing up of Bertrand Russell and Lobachevsky / Bolyai attributable to "Babelogic"), along with a new ending to the Beginning...

Astor Place Barber, Audrey Nasar

Journal of Humanistic Mathematics

"Astor Place Barber" is a short story about a math professor and a barber. It plays with the logical concept of a paradox via the Barber's Paradox, which, made famous by Bertrand Russell, tells the story of a barber who both shaves himself and does not shave himself.

Locked In Functions: A Short Poem For Robert Langlands, Virgilio A. Rivas

Journal of Humanistic Mathematics

This short poem is inspired by Robert Langlands, recipient of the 2018 Abel Prize. The poem tries to sum up in poetic language, as brief but substantial as it can be, the philosophical and rhetorical connotation of his contributions to mathematics, from automorphic forms to number theory, and the famous Langlands programme, among others. Also partly inspired by Edward Frenkel's tribute to Langlands, the book Love and Mathematics, the poem seeks to capture the philosophical beauty of mathematics that privileges the importance of 'functions' over 'passions', consistent with Langlands' purely mathematical side.

Unsolved Haiku, Scott W. Williams

Journal of Humanistic Mathematics

This poem describes the still unsolved 1937 conjecture of Lloyd Collatz: Do repeated applications of the algorithm described yield the number 1?

Mathematics, Kim Regnier Jongerius

Journal of Humanistic Mathematics

Inspired by the song "Memories" from the musical Cats, this work describes some of the frustrations and joys inherent in mathematical work.

Wartime Logic, Tony Bedenikovic

Journal of Humanistic Mathematics

No abstract provided.

Self-Reference And Diagonalisation, Joël A. Doat

Journal of Humanistic Mathematics

This poem is an exercise on self-reference and diagonalisation in mathematics featuring Turing’s proof of the undecidability of the halting problem, Cantor’s cardinality argument, the Burali-Forti paradox, and Epimenides' liar paradox.

Book Review: Algebra The Beautiful: An Ode To Math’S Least-Loved Subject By G. Arnell Williams, Judith V. Grabiner

Journal of Humanistic Mathematics

In his book Algebra the Beautiful, G. Darnell Williams has undertaken a challenging job – to show the importance, deep structure, intellectual connections, and sheer beauty of classroom algebra. This review describes some of the questions the book raises, the historical and cultural context it provides, and the intellectual apparatus it deploys.

Poetry Folder: Mathematical Constants Beyond The Half-Circle

Journal of Humanistic Mathematics

In our July 2022 issue, we announced an open call for poetry about mathematical constants other than pi. And you delivered. This folder contains five eclectic poems celebrating those constants beyond the half-circle, written by Robin Chapman, John Donoghue, Kevin Farey, Lawrence M. Lesser, and E. R. Lutken.

Enjoy!

Anneli Lax: They Think, Therefore We Are, Elena Anne Corie Marchisotto

Journal of Humanistic Mathematics

No abstract provided.

Walking Alone: My Career In Mathematics, Maohua Le, Yongzhong Hu

Journal of Humanistic Mathematics

In this article, dictated by Maohua Le and arranged by Yongzhong Hu, Professor Le briefly recounts his legendary experience of self-study mathematics, which reflects the life experiences of his generation of Chinese people.

Mathaphor As A Literary Tool, Sarah Voss

Journal of Humanistic Mathematics

Drawing from one of my recent sermons, I chart the path of mathaphor (metaphor drawn from mathematics) as a literary tool. Following a short history of the concept, I detail contemporary author Colum McCann’s significant use of a geometric term to unveil and encourage compassion.

Blending Mathematics Teaching With Kindness, Kien H. Lim, Anthony Matsuura

Journal of Humanistic Mathematics

Mathematics can be intellectually demanding, engaging, and fulfilling. Learning mathematical concepts adequately warrants an environment where students can err without penalty, shame, or hurtful consequences. Teaching mathematics efficaciously depends on the trusting relationship between the teacher and the students. We advocate blending mathematics teaching with kindness because it benefits the teacher, the students, and society. Kindness, niceness, caring, and benevolence are interrelated but not synonymous. We outline four progressive levels of kindness: conditional, superficial, optimal, and genuine. Blending mathematics teaching and kindness effectively requires the teacher to decenter from their own perspectives and adopt the student’s perspective as the student …

Figure-Ground Perception: A Poem Proof, Richard Delaware

Journal of Humanistic Mathematics

This is a proof, in poetic form, of a bit of real analysis, more specifically involving the topology of accumulation points, that exploits the human optical phenomenon of figure-ground perception. Sometimes it is not a change in content, but a snap shift in point of view that yields a proof.

Using Bloom's Taxonomy For Math Outreach Within And Outside The Classroom, Manmohan Kaur

Journal of Humanistic Mathematics

Not everyone is a great artist, but we don’t often hear, “I dislike art.” Most people are able to appreciate visual arts, music and sports, without necessarily excelling in it themselves. On the other hand, the phrase “I dislike math” is widely prevalent. This is especially ironic in our current society, where mathematics affects our day-to-day activities in essential ways such as e-commerce and e-mail. This paper describes the opportunity to popularize mathematics by focusing on its fun and creative aspects, and illustrates this opportunity through a brief discussion of interdisciplinary topics that expose the beauty, elegance and value of …

The Mathematics Of The Harp: Modeling The Classical Instrument And Designing Futuristic Ones, Cristina Carr, Daniel Chioffi, Maya Glenn, Stefan O. Nita, Vlad N. Nita, Bogdan G. Nita

Journal of Humanistic Mathematics

We analyze and model the neck of the classical harp based on the length of the strings, their tension and density. We then use the results to design new and innovative harp shapes by adjusting the parameters of the model.

Lessons From Human Experience: Teaching A Humanities Course Made Me A Better Math Teacher, Erin Griesenauer

Journal of Humanistic Mathematics

As a professor at a Liberal Arts college, I recently taught a General Education course called Human Experience. Far from my normal experiences in the mathematics classroom, in Human Experience I was tasked with teaching topics from the humanities, including art, philosophy, history, and political science. Teaching this course was challenging, but it was also transformative. Teaching a course so far from my background gave me the opportunity to experiment with different pedagogical techniques and to reflect on how I set up my math classes. I learned many lessons that I have brought back to my math classes—lessons that have …

The Nothing That Really Matters, Szilárd Svitek

Journal of Humanistic Mathematics

Zero has (a) special role(s) in mathematics. In the current century, we take negative numbers and zero for granted, but we should also be aware that their acceptance and their emergence in mathematics, and their ubiquity today, have not come to happen as rapidly as, for example, that of natural numbers. Students can quickly become confused by the question: is zero a natural number? The answer is simple: a matter of definition. The history of zero and that of negative numbers are closely linked. It was in the calculations of debts that the negative numbers first appeared, where the state …

The Use And Development Of Mathematics Within Creative Literature, Toby S C Peres

Journal of Humanistic Mathematics

This paper presents a study on the extent to which creative literature been used as a vessel to carry forward the development of mathematical thought. The role of mathematics as a driving force for literature is highlighted, and while many examples exist that clearly show an attempt to disperse mathematical ideas, with Lewis Carroll, OuLiPo and ancient poetry considered, the argument that the sole purpose of the writings was for the sake of mathematical development is not clear-cut.

The Genesis Of A Theorem, Osvaldo Marrero

Journal of Humanistic Mathematics

We present the story of a theorem's conception and birth. The tale begins with the circumstances in which the idea sprouted; then is the question's origin; next comes the preliminary investigation, which led to the conjecture and the proof; finally, we state the theorem. Our discussion is accessible to anyone who knows mathematical induction. Therefore, this material can be used for instruction in a variety of courses. In particular, this story may be used in undergraduate courses as an example of how mathematicians do research. As a bonus, the proof by induction is not of the simplest kind, because it …

Where Do Babies Come From?, Marcio Luis Ferreira Nascimento

Journal of Humanistic Mathematics

According to European folklore, popularized by a fairy tale, storks are responsible for bringing babies to new parents. This probably came from observation in certain European countries, such as Norway, Netherlands or Germany, that storks nesting on the roofs of households were believed to bring good luck, as the possibility of new births. People love stories, but correlation simply means that there is a relationship between two factors that tells nothing about the direction of said relationship, if any. Another possibility is simple coincidence. Let us say that it’s possible that one factor causes another. It’s also possible that the …

Teaching Mathematics After Covid: A Conversation Not A Discussion, Wendy Ann Forbes, Joyce Mgombelo

Journal of Humanistic Mathematics

Inspired by Brent Davis' conceptualization of listening and conversation in his book Teaching Mathematics: Toward a Sound Alternative, we propose how we as a mathematics education community may move forward by continuing in the conversation that emerged from COVID. We encourage all involved to listen rather than assume a discussion-oriented stance. Using an enactivist lens, we look at the pandemic learning space, give an overview of the education conversation that emerged in Ontario, and offer a way to rethink Mathematics Education within the frame of a conversation. We believe that if mathematics education is to engage learners in a meaningful …

A Classification Of Musical Scales Using Binary Sequences, Thomas Hillen

Journal of Humanistic Mathematics

Every beginning music student has gone through the four main musical scales: major, natural minor, harmonic minor, and melodic minor. And some might wonder, why those four and not five, or six, or just three? Here we show that a mathematical classification can be used to identify these scales as representatives of certain scale families. Moreover, the classification reveals another scale family, which is much less known: the harmonic major scale. We find that each scale family contains exactly seven scales, which include the modes (dorian, phrygian,...) and other scales such as the Romanian, …

Human-Machine Collaboration In The Teaching Of Proof, Gila Hanna, Brendan P. Larvor, Xiaoheng (Kitty) Yan

Journal of Humanistic Mathematics

This paper argues that interactive theorem provers (ITPs) could play an important role in fostering students’ appreciation and understanding of proof and of mathematics in general. It shows that the ITP Lean has three features that mitigate existing difficulties in teaching and learning mathematical proof. One is that it requires students to identify a proof strategy at the start. The second is that it gives students instant feedback while allowing them to explore with maximum autonomy. The third is that elementary formal logic finds a natural place in the activity of creating proofs. The challenge in using Lean is that …