Digital Commons Network^™

18f-Fdg Pet/Ct Prediction Of Treatment Outcomes In Human Papillomavirus–Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results From Nrg-Hn002, Rathan M Subramaniam, Lyudmila Demora, Min Yao, Sue S Yom, Maura Gillison, Jimmy J Caudell, John Waldron, Ping Xia, Christine H Chung, Minh Tam Truong, Michelle Echevarria, Jason W Chan, Jessica L Geiger, Loren Mell, Samantha Seaward, Wade L Thorstad, Jonathan Jay Beitler, Khalil Sultanem, Diagjin Blakaj, Quynh-Thu Le

Faculty, Staff and Student Publications

The purpose of this study was to determine the negative predictive value (NPV) of a 12- to 14-wk posttreatment PET/CT for 2-y progression-free survival (PFS) and locoregional control (LRC) in patients with p16-positive locoregionally advanced oropharyngeal cancer (LA-OPC). Study was a secondary endpoint in NRG-HN002, a noncomparative phase II trial in p16-positive LA-OPC, stage T1-T2, N1-N2b or T3, N0-N2b, and ≤10 pack-year smoking. Patients were randomized in a 1:1 ratio to reduced-dose intensity-modulated radiotherapy (IMRT) with or without cisplatin. Methods: PET/CT scans were reviewed centrally. Tumor response evaluations for the primary site, right neck, and left neck were performed using …

Medicaid Expansion And Postoperative Mortality In Women With Gynecologic Cancer: A Difference-In-Difference Analysis, Sarah P Huepenbecker, Shuangshuang Fu, Charlotte C Sun, Hui Zhao, Kristin M Primm, Sharon H Giordano, Larissa A Meyer

Faculty, Staff and Student Publications

BACKGROUND: The association between Medicaid expansion and postoperative mortality after surgery for gynecologic cancer is unknown. Our objective was to compare 30- and 90-day postoperative mortality after gynecologic cancer surgery before and after 2014 in states that did and did not expand Medicaid.

METHODS: We searched the National Cancer Database for women aged 40-64 years old between 2010 and 2016 who underwent surgery for a primary gynecologic malignancy. We used pre/post and quasi-experimental difference-in-difference (DID) multivariable logistic regressions to evaluate mortality pre-2014 (2010-2013) and post-2014 (2014-2016) for states that did and did not expand Medicaid in January 2014. We completed …

Deep Learning-Based Pathology Image Analysis Predicts Cancer Progression Risk In Patients With Oral Leukoplakia, Xinyi Zhang, Frederico O Gleber-Netto, Shidan Wang, Roberta Rayra Martins-Chaves, Ricardo Santiago Gomez, Nadarajah Vigneswaran, Arunangshu Sarkar, William N William, Vassiliki Papadimitrakopoulou, Michelle Williams, Diana Bell, Doreen Palsgrove, Justin Bishop, John V Heymach, Ann M Gillenwater, Jeffrey N Myers, Renata Ferrarotto, Scott M Lippman, Curtis Rg Pickering, Guanghua Xiao

Faculty, Staff and Student Publications

BACKGROUND: Oral leukoplakia (OL) is associated with an increased risk for oral cancer (OC) development. Prediction of OL cancer progression may contribute to decreased OC morbidity and mortality by favoring early intervention. Current OL progression risk assessment approaches face large interobserver variability and is weakly prognostic. We hypothesized that convolutional neural networks (CNN)-based histology image analyses could accelerate the discovery of better OC progression risk models.

METHODS: Our CNN-based oral mucosa risk stratification model (OMRS) was trained to classify a set of nondysplastic oral mucosa (OM) and a set of OC H&E slides. As a result, the OMRS model could …

On Target Methods To Induce Abscopal Phenomenon For Off-Target Effects: From Happenstance To Happenings, Blessie Elizabeth Nelson, Jacob J Adashek, Steven H Lin, Vivek Subbiah

Faculty, Staff and Student Publications

Although the "abscopal phenomenon" has been described several decades ago, this phenomenon lately has been obtaining momentous traction with the dawn of immune-based therapies. There has been increased cross talk among radiation oncologists, oncologists and immunologists and consequently a surge in the number of prospective clinical trials. This must be coupled with translation work from these clinical trials to aid in eventual identification of patients who may benefit. Abscopal effects may be induced by local and systemic methods, conventional radiotherapy, particle radiation, radionucleotide methods, cryoablation and brachytherapy. These approaches have all been reported to be stimulate abscopal effect. Immune induction …

2023-03-00 Newsletter, Morehead State University. Staff Congress.

Staff Congress Records

Staff Congress newsletter from March of 2023.

Salvation In Hinduism, J. L. Samir

Journal of Adventist Mission Studies

The teachings of Hinduism have existed for thousands of years and continue to influence many cultures, especially those of South Asia. The philosophical teachings of Hinduism are complex and attractive to its adherents; however, the Hindu faith is easily misunderstood by many Westerners. Christianity as a religious institution was mostly developed in the context of a Western worldview. In contrast, Hinduism and its teachings are solely built on an Eastern philosophical and religious system dating back to the eighth century BCE. This article seeks to understand the teachings of salvation as found in the Bhagavad Gita and to contrast those …

Evaluating Bone Marrow Dosimetry With The Addition Of Bone Marrow Structures To The Medical Internal Radiation Dose Phantom, Kristine L Ferrone, Charles E Willis, Fada Guan, Jingfei Ma, Leif E Peterson, Stephen F Kry

Faculty, Staff and Student Publications

Background: Reliable estimates of radiation dose to bone marrow are critical to understanding the risk of radiation-induced cancers. Although the medical internal radiation dose phantom is routinely used for dose estimation, bone marrow is not defined in the phantom. Consequently, methods of indirectly estimating bone marrow dose have been implemented based on dose to surrogate volumes or average dose to soft tissue.

Methods: In this study, new bone marrow structures were implemented and evaluated to the medical internal radiation dose phantom in geant4, offering improved fidelity. The dose equivalent to the bone marrow was calculated across medical, occupational, and space …

Frontline Combination Of Ponatinib And Hyper-Cvad In Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: 80-Months Follow-Up Results, Hagop Kantarjian, Nicholas J Short, Nitin Jain, Koji Sasaki, Xuelin Huang, Fadi G Haddad, Issa Khouri, Courtney D Dinardo, Naveen Pemmaraju, William Wierda, Guillermo Garcia-Manero, Partow Kebriaei, Rebecca Garris, Sanam Loghavi, Jeffrey Jorgensen, Monica Kwari, Susan O'Brien, Farhad Ravandi, Elias Jabbour

Faculty, Staff and Student Publications

Background:

The combination of ponatinib, a third generation BCR::ABL1 tyrosine kinase inhibitor (TKI), with Hyper-CVAD chemotherapy resulted in high rates of complete molecular remissions and survival, without the need for SCT in most patients with Philadelphia chromosome(Ph)-positive acute lymphocytic leukemia (ALL). Confirming these results in a large cohort of patients followed with longer follow-up would establish this regimen as a new standard of care.

Methods:

Adults with newly diagnosed Ph-positive ALL were treated with the Hyper-CVAD regimen. Ponatinib was added as 45 mg daily x 14 during induction, then 45 mg daily continuously (first 37 patients) or 30 mg daily …

Disruption Of Gcn2 Pathway Aggravates Vascular And Parenchymal Remodeling During Pulmonary Fibrosis, Diana Santos-Ribeiro, Marylène Lecocq, Michèle De Beukelaer, Stijn Verleden, Caroline Bouzin, Jérôme Ambroise, Peter Dorfmuller, Yousef Yakoub, François Huaux, Rozenn Quarck, Harry Karmouty-Quintana, Maria-Rosa Ghigna, Juliette Bignard, Sophie Nadaud, Florent Soubrier, Sandrine Horman, Frederic Perros, Laurent Godinas, Charles Pilette

Faculty, Staff and Student Publications

Pulmonary fibrosis (PF) and pulmonary hypertension (PH) are chronic diseases of the pulmonary parenchyma and circulation, respectively, which may coexist, but underlying mechanisms remain elusive. Mutations in the GCN2 (general control nonderepressible 2) gene (EIF2AK4 [eukaryotic translation initiation factor 2 alpha kinase 4]) were recently associated with pulmonary veno-occlusive disease. The aim of this study is to explore the involvement of the GCN2/eIF2α (eukaryotic initiation factor 2α) pathway in the development of PH during PF, in both human disease and in a laboratory animal model. Lung tissue from patients with PF with or without PH was collected at the …

Scholarly Publishing Support, Joanne Romano

TMC Library Newsletter (2015-)

A Read & Publish license allows libraries to provide their affiliated author's open-access publishing options at no additional cost, or at a discount rate. Under this type of publisher license, once an author’s manuscript is accepted, the Article Processing Charges (APC) are either discounted or eliminated at the point of payment. The pricing model and approval process varies widely among publishers.

The library’s Scholarly Publishing LibGuide has information on how to use this service

Building Skills And Collaboration For College Success: Lessons From The Detroit College Success Professional Learning Community For Youth Development Professionals, Sara Plachta Elliott, Sarah Szurpicki, Onjila Odeneal, Megan Fenkell

The Foundation Review

From 2018 through 2020, the Jamie and Denise Jacob Family Foundation made grants to 17 youth development organizations in Detroit that were at varying levels of readiness to advance college success outcomes with their program alumni. At the same time, it was funding three collaborating capacity-building organizations to structure and facilitate a professional learning community that would support the youth programs in improving outcomes for “striving students” — young people who are less likely to graduate college because they come from families or communities with less access to opportunity and resources. In total, 17 YDOs and four schools participated in …

The Bg News March 1, 2023, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 01, 2023. Volume 102-Issue 20.

Volume Of Subcortical Brain Regions In Social Anxiety Disorder: Mega-Analytic Results From 37 Samples In The Enigma-Anxiety Working Group, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Alyssa R. Amod, Max A. Laansma, Laura S. Van Velzen, Moji Aghajani, Kevin Hilbert, Hyuntaek Oh, Ramiro Salas, Anderson M. Winkler

School of Medicine Publications

There is limited convergence in neuroimaging investigations into volumes of subcortical brain regions in social anxiety disorder (SAD). The inconsistent findings may arise from variations in methodological approaches across studies, including sample selection based on age and clinical characteristics. The ENIGMA-Anxiety Working Group initiated a global mega-analysis to determine whether differences in subcortical volumes can be detected in adults and adolescents with SAD relative to healthy controls. Volumetric data from 37 international samples with 1115 SAD patients and 2775 controls were obtained from ENIGMA-standardized protocols for image segmentation and quality assurance. Linear mixed-effects analyses were adjusted for comparisons across seven …

Russia-Ukraine Conflict: The War At Sea, Raul (Pete) Pedrozo

International Law Studies

Although much has been written about the Russia-Ukraine conflict, most writings have focused on land warfare. This article explores the conflict at sea and a host of legal issues arising from that aspect of the conflict. The article begins with a discussion of a series of events at sea that preceded the Russian invasion in 2022, including the Kerch Strait incidents and interference with freedom of navigation in the Black Sea. It then discusses multiple post-invasion legal issues involving the war at sea, including access to the Black Sea, maritime exclusion zones, naval mines, naval bombardment, unmanned maritime systems, targeting …

A Systems Perspective On Water Markets: Barriers, Bright Spots, And Building Blocks For The Next Generation, Dustin Garrick, Soumya Balasubramanya, Melissa Beresford, Amber Wutich, Gina G. Gilson, Isabel Jorgensen, Nicholas Brozović, Michael Cox, Xiaoping Dai, Sophie Erfurth, Renata Rimšaitė, Jesper Svensson, Julia Talbot Jones, Hita Unnikrishnan, Charles Wight, Sergio Villamayor-Tomas, Karla Vazquez Mendoza

Faculty Research, Scholarly, and Creative Activity

No abstract provided.

Cooperative Filtering And Parameter Identification For Advection-Diffusion Processes Using A Mobile Sensor Network, Jie You, Ziqiao Zhang, Fumin Zhang, Wencen Wu

Faculty Research, Scholarly, and Creative Activity

This article presents an online parameter identification scheme for advection-diffusion processes using data collected by a mobile sensor network. The advection-diffusion equation is incorporated into the information dynamics associated with the trajectories of the mobile sensors. A constrained cooperative Kalman filter is developed to provide estimates of the field values and gradients along the trajectories of the mobile sensors so that the temporal variations in the field values can be estimated. This leads to a co-design scheme for state estimation and parameter identification for advection-diffusion processes that is different from comparable schemes using sensors installed at fixed spatial locations. Using …

Healthcare Worker's Understanding Of Perinatal Depression And Maternal Mental Health Service Needs In Rural Kenya, Deepika Goyal, Kantoniony M. Rabemananjara, Sandraluz Lara-Cinisomo, Huynh Nhu Le

Faculty Research, Scholarly, and Creative Activity

Background: Perinatal depression is a significant maternal mental health issue in sub-Saharan Africa. Because of the severe shortage of mental health specialists in this region, healthcare workers can be trained to deliver mental health services. Yet, little research has examined their views about maternal mental health. Aims: To help inform the development of a perinatal depression screening program, the aim of this pilot study was to explore the knowledge and understanding of perinatal depression among healthcare workers in rural Kenya. Methods: Fourteen healthcare workers participated in focus group interviews. Results: Content analysis of interview data yielded three primary themes: 1) …

How Ethnic Studies Faculty Use Streaming Video: Instructional Needs, Applications, And Challenges, Keri Prelitz, Nick Szydlowski, Mantra Roy, Anthony Davis, Ann Agee, Emily K. Chan

Faculty Research, Scholarly, and Creative Activity

While there have been studies on faculty use of streaming video resources in academic libraries, none have focused on the specific needs of ethnic studies faculty. Using a thematic analysis of semi-structured interviews with 13 ethnic studies faculty from two public university campuses, this study found that faculty engagement with video is based upon a pedagogical strategy that responds to the specific demands and goals of ethnic studies curricula, while centering on student needs by using free resources whenever possible. Within this paradigm, faculty choose from three categories of content: key primary and secondary sources; flexible supporting sources; and current …

The First Amendment And The Second Sex, Cristina Carmody Tilley

Faculty Publications

Modern American law describes speech in stereotypically masculine terms: it is a “marketplace” where participants “joust” for dominance. Predictably, today’s speech jurisprudence can be hostile to the female voice, implicitly condoning gendered death threats, rape threats, doxing, and trolling as the necessary price of a vibrant national discourse. Unpredictably, the American Civil Liberties Union (“ACLU”) and its leading women drafted the blueprint for this modern speech edifice. The First Amendment and the Second Sex traces the ACLU campaign to dismantle a nineteenth-century speech regime that silenced some men while protecting many women. And it suggests that ACLU feminists—intent on securing …

Phase Iia Study Of Survaxm Plus Adjuvant Temozolomide For Newly Diagnosed Glioblastoma, Manmeet Ahluwalia

All Publications

Purpose: Despite intensive treatment with surgery, radiation therapy, temozolomide (TMZ) chemotherapy, and tumor-treating fields, mortality of newly diagnosed glioblastoma (nGBM) remains very high. SurVaxM is a peptide vaccine conjugate that has been shown to activate the immune system against its target molecule survivin, which is highly expressed by glioblastoma cells. We conducted a phase IIa, open-label, multicenter trial evaluating the safety, immunologic effects, and survival of patients with nGBM receiving SurVaxM plus adjuvant TMZ following surgery and chemoradiation (ClinicalTrials.gov identifier: NCT02455557).

Methods: Sixty-four patients with resected nGBM were enrolled including 38 men and 26 women, in the age range …

A Proposed Algorithm For Hiding A Text In An Image Using Qr Code, Haider Saeed Wdhayeh, Raghad Abdulaali, Athraa Jasim Mohammed

Iraqi Journal of Computers, Communications, Control and Systems Engineering

In this paper, an algorithm to hide information in an image using QR code technology is presented. QR Code “QUICK RESPONSE CODE” is a two-dimensional array that can include different types of data and was first developed in 1993 for the Japanese Toyota Corporation for the purpose of tracking products through production and marketing. The researchers paid great attention to QR code technology especially in the field of information security. The proposed algorithm in this paper hides the secret text in the image in a random way by generating random positions and using the LSB “Least Significant Bit” method. After …

Spectral And Energy Efficiency Analysis For Beamforming Optimization Objectives For Wireless Massive Mimo Systems, Zaid Hashim Jaber, Dheyaa Jasim, Ahmed Sabah Al-Araji

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Massive Multiple-Input Multiple-Output (MIMO) is an extension of the conventional MIMO in the wireless systems which improves both of the access density and the spectral efficiency by adding a massive number of antenna array at the base station (BS). Massive MIMO increases the spectral efficiency by using the beamforming. Besides, the beamforming in massive MIMO improves the energy efficiency by focusing the energy in the desired direction instead of the omnidirectional propagation. In this paper, we propose and discuss different beamforming objectives in both the uplink and the downlink channels. These proposed objectives can be either use the beamforming of …

Data Analytics And Blockchain: A Review, Safa S. Abdul-Jabbar, Alaa K., Rana F. Ghani

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Blockchain technology relies on cryptographic techniques that provide various advantages, such as trustworthiness, collaboration, organization, identification, integrity, and transparency. Meanwhile, data analytics refers to the process of utilizing techniques to analyze big data and comprehend the relationships between data points to draw meaningful conclusions. The field of data analytics in Blockchain is relatively new, and few studies have been conducted to examine the challenges inVolved in Blockchain data analytics. This article presents a systematic analysis of how data analytics affects Blockchain performance, with the aim of investigating the current state of Blockchain-based data analytics techniques in research fields and exploring …

A Review: E-Voting Security In Mobile Fog Computing, Asmaa Ibrahim Hussieen, Abeer Tariq, Ekhlas Khalaf Gbash

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Conventional voting activities are often replaced by electronic voting (EV) in light of the quick expansion of the Internet. For a variety of reasons, various nations have lately switched to EV rather than conventional voting. Different EV systems were presented up to this point. In both practical and theoretical fields, on the other hand, there is no perfect solution. To meet such objectives, the researchers strive for preserving cryptographic primitives when developing high-efficiency e-voting schemes. The concept of fog computing was developed to improve network infrastructure to satisfy the demands of large amounts of data the same time as also …

Modified Tracking Differentiator For Enhancing The Performance Of Exoskeleton Knee System Based On Active Disturbance Rejection Control, Nasir Ahmed Alawad, Amjad J., Ahmed Sabah Al-Araji

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Exoskeleton robots help users with mechanical forces by recognizing their intentions, and they require a lot of energy efficiency, a lot of load capacity, and a good fit. A basic one degree of freedom (DOF) construction was devised in this work, which was mostly used in the knees of exoskeleton robots. The exoskeleton is a small robotic device used for knee injury training. It is a nonlinear mathematical model with many mechanical factors that might vary and produce uncertainty, as well as external disturbances that can be utilized to monitor control. The transitioning process is frequently organized using tracking differentiator …

Interference Effect Evaluation With Radio Over Fiber In 5g Mobile System, Khasraw A. Abdulrahman, Jalal J

Iraqi Journal of Computers, Communications, Control and Systems Engineering

The fifth generation (5G) of mobile technology is emerging as a advance communication network, delivering elevated speeds, coverage and reliability, this technology like other technologies not clear from drawbacks and limitations, 5G mobile system like other mobile systems 4G, 3G and 2G affected by interference and signal quality is going to be decreased because of higher number of C-Node-Bs which is because higher frequency and smaller coverage, in this paper, interference effect has been studied with both types cochannel and adjacent channel, best case and worst cases has been presented simulated and calculated the signal to interference ratio vs cluster …

Comparative Between Backstepping And Adaptive Backstepping Control For Controlling Prosthetic Knee, Mayyasah Ali Salman, Saleem Khalefa

Iraqi Journal of Computers, Communications, Control and Systems Engineering

The lower limb amputees are increasing day by day. This has led to an increase in research in the field of prosthetic knee. In this work, a prosthetic knee was designed and developed to assist human movements and more quality of life for millions of individuals who have lost lower limbs. The dynamic model and parameter identification of a two degree of freedom (2-DOF) joint prosthetic knee is derived according to the Lagrangian dynamic approach. The two controllers Backstepping and Adaptive Backstepping are adopted to control the system. Stability analysis and controller design dependent on Lyapunov theory are assessed to …

Review On Fractal Video And Image Compression Techniques, Baydaa Sh. Abood, Hanan A., Amean S. Al-Safi

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Compression of images process is a step in the image processing. It is concerned with the transmission and storage of digitally created images. Fractal coding is a potential image and video compression approach with good reconstruction fidelity and relatively large compression ratios, because of its simplicity and great performance; fractal image compression (FIC) is a particularly popular approach in image compression applications. However, it has a significant disadvantage in the form of a long encoding time. This is because encoding any small bit necessitates a massive similarity search in the original data As a result; the FIC search time is …

Dynamic Model Based On The Gaming Argumentation Framework (Dgaf): Foreign Exchange Market As A Case Of Study, Adnan T. Kareem, Hasanen S., Ahmed T. Sadiq

Iraqi Journal of Computers, Communications, Control and Systems Engineering

argumentation has become an attraction recently, because it is widely used in decision-making, at 1994 Dung invented a new argumentation model, called Argumentation Framework AF. This system investigates assaults of arguments, and it also works away on attributes, this model is designed to take care of argument attacks among them, without paying attention to how the sentences are formulated or arranged, and identify the supporting and supporting arguments. It is also possible for a group of experts, to evaluate arguments to resolve the debate about the current problem, by determining the extent to which a particular argument affects the other …

D-Gift: Cryptography Algorithm Development Using Dynamic Dna And A Chaos Map, Ghada K. Emad, Soukaena Hassan

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Recently, the growth of data transmission through various networks has the necessity for an elevated level of security. Encryption is one of the essential technologies for protecting and ensuring the integrity of IoT devices. Secure communication among constrained devices is critical during data transmission from the client to the server devices. Lightweight cipher algorithms are defined as a secure solution for devices with limited computational functions and memory. On the other hand, most lightweight algorithms suffer from a trade-off between complexity and speed to produce a robust cipher algorithm. This paper evaluates the effectiveness of an image encryption technique that …