Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 564391 - 564420 of 5165752

Full-Text Articles in Entire DC Network

Cellular Heterogeneity And Stem Cells Of Vascular Endothelial Cells In Blood Vessel Formation And Homeostasis: Insights From Single-Cell Rna Sequencing, Taku Wakabayashi, Hisamichi Naito Mar 2023

Cellular Heterogeneity And Stem Cells Of Vascular Endothelial Cells In Blood Vessel Formation And Homeostasis: Insights From Single-Cell Rna Sequencing, Taku Wakabayashi, Hisamichi Naito

Wills Eye Hospital Papers

Vascular endothelial cells (ECs) that constitute the inner surface of blood vessels are essential for new vessel formation and organ homeostasis. ECs display remarkable phenotypic heterogeneity across different organs and the vascular tree during angiogenesis and homeostasis. Recent advances in single cell RNA sequencing (scRNA-seq) technologies have allowed a new understanding of EC heterogeneity in both mice and humans. In particular, scRNA-seq has identified new molecular signatures for arterial, venous and capillary ECs in different organs, as well as previously unrecognized specialized EC subtypes, such as the aerocytes localized in the alveolar capillaries of the lung. scRNA-seq has also revealed …

Go to article

Rigor And Reliability Of Qualitative Research Conducted In Various Languages: Fundamentals And Their Application, Shweta Jain Verma Dr., Puja Gulati, Vishav Kumar Dhiman, Jeyaraj Durai Pandian Mar 2023

Rigor And Reliability Of Qualitative Research Conducted In Various Languages: Fundamentals And Their Application, Shweta Jain Verma Dr., Puja Gulati, Vishav Kumar Dhiman, Jeyaraj Durai Pandian

The Qualitative Report

Lack of a common language between researcher and participants, especially when participants speak different languages, complicates and makes the qualitative research process more difficult. Since language is the vehicle through which meaning is eventually communicated to the reader, interpretation and translation are essential to qualitative research. The researcher must adopt the principal tenets of cross language research to extrapolate the knowledge to all the spheres for a methodologically reliable and valid framework that is culturally sensitive in this situation. The purpose of the article is to acquaint qualitative researchers, including physician-researchers, with the fundamentals of qualitative study being carried out …

Go to article

Unh Announces 2023 Commencement Speakers, Keith Testa Mar 2023

Unh Announces 2023 Commencement Speakers, Keith Testa

UNH Today Archive

No abstract provided.

Go to article

The Prospector, March 21, 2023, Utep Student Publications Mar 2023

The Prospector, March 21, 2023, Utep Student Publications

The Prospector

Headline: "No Más Bebés": Forced Sterilization in 1970's America

Go to article

Circulating Plasma Exosomal Proteins Of Either Shiv-Infected Rhesus Macaque Or Hiv-Infected Patient Indicates A Link To Neuropathogenesis, Partha K. Chandra, Stephen E. Braun, Sudipa Maity, Jorge A. Castorena-Gonzalez, Hogyoung Kim, Jeffrey G. Shaffer, Sinisa Cikic, Ibolya Rutkai, Jia Fan, Jessie J. Guidry, David K. Worthylake, Chenzhong Li, Asim B. Abdel-Mageed, David W. Busija Mar 2023

Circulating Plasma Exosomal Proteins Of Either Shiv-Infected Rhesus Macaque Or Hiv-Infected Patient Indicates A Link To Neuropathogenesis, Partha K. Chandra, Stephen E. Braun, Sudipa Maity, Jorge A. Castorena-Gonzalez, Hogyoung Kim, Jeffrey G. Shaffer, Sinisa Cikic, Ibolya Rutkai, Jia Fan, Jessie J. Guidry, David K. Worthylake, Chenzhong Li, Asim B. Abdel-Mageed, David W. Busija

School of Medicine Faculty Publications

Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50–60% of HIV-infected patients suffer from HIV-associated neurocognitive disorders (HAND). Studies are uncovering the role of extracellular vesicles (EVs), especially exosomes, in the central nervous system (CNS) due to HIV infection. We investigated links among circulating plasma exosomal (crExo) proteins and neuropathogenesis in simian/human immunodeficiency virus (SHIV)-infected rhesus macaques (RM) and HIV-infected and cART treated patients (Patient-Exo). Isolated EVs from SHIV-infected (SHIV-Exo) and uninfected (CTL-Exo) RM were predominantly exosomes (particle size < 150 nm). Proteomic analysis quantified 5654 proteins, of which 236 proteins (~4%) were significantly, differentially expressed (DE) between SHIV-/CTL-Exo. Interestingly, different CNS cell specific markers were abundantly expressed in crExo. Proteins involved in latent viral reactivation, neuroinflammation, neuropathology-associated interactive as well as signaling molecules were expressed at significantly higher levels in SHIV-Exo than CTL-Exo. However, proteins involved in mitochondrial biogenesis, ATP production, autophagy, endocytosis, exocytosis, and cytoskeleton organization were significantly less expressed in SHIV-Exo than CTL-Exo. Interestingly, proteins involved in oxidative stress, mitochondrial biogenesis, ATP production, and autophagy were significantly downregulated in primary human brain microvascular endothelial cells exposed with HIV+/cART+ Patient-Exo. We showed that Patient-Exo significantly increased blood–brain barrier permeability, possibly due to loss of platelet endothelial cell adhesion molecule-1 protein and actin cytoskeleton structure. Our novel findings suggest that circulating exosomal proteins expressed CNS cell markers—possibly associated with viral reactivation and neuropathogenesis—that may elucidate the etiology of HAND.

Go to article

Enhancing Patient Experience Through Nurse Bundling Strategies, Ron C. Carpio Mar 2023

Enhancing Patient Experience Through Nurse Bundling Strategies, Ron C. Carpio

DNP and Student Works

Federal regulations have shifted healthcare systems to focus more on providing quality of care rather than quantity of care. Patient experiences that include nursing communication are important quality measures that have positive impact on satisfaction ratings. The project used nurse bundling strategies (Acknowledge, Introduce, Duration, Explanation, Thank You [AIDET], purposeful/hourly rounding, and bedside shift report) guided by servant leadership principles to improve patients' experiences and overall hospital quality of care experiences. Pre and post education on the bundling approach and servant leadership theory and principles, registered nurses in the emergency department completed an electronic, 23-item Servant Leadership Questionnaire (SLQ) survey …

Go to article

The Link March 21, 2023, Access To Justice Institute Mar 2023

The Link March 21, 2023, Access To Justice Institute

The Link Newsletter

No abstract provided.

Go to article

Unmarked: Intellectual Property And Geography, Lorie Graham, Stephen Mcjohn Mar 2023

Unmarked: Intellectual Property And Geography, Lorie Graham, Stephen Mcjohn

Minnesota Journal of Law, Science & Technology

No abstract provided.

Go to article

Comparing Self-Report Assessments And Scenario-Based Assessments Of Systems Thinking Competence, Kirsten A. Davis, Dustin Grote, Hesam Mahmoudi, Logan Perry, Navid Ghaffarzadegan, Jacob Grohs, Niyousha Hosseinichimeh, David B. Knight, Konstantinos Triantis Mar 2023

Comparing Self-Report Assessments And Scenario-Based Assessments Of Systems Thinking Competence, Kirsten A. Davis, Dustin Grote, Hesam Mahmoudi, Logan Perry, Navid Ghaffarzadegan, Jacob Grohs, Niyousha Hosseinichimeh, David B. Knight, Konstantinos Triantis

School of Engineering Education Faculty Publications

Self-report assessments are used frequently in higher education to assess a variety of constructs, including attitudes, opinions, knowledge, and competence. Systems thinking is an example of one competence often measured using self-report assessments where individuals answer several questions about their perceptions of their own skills, habits, or daily decisions. In this study, we define systems thinking as the ability to see the world as a complex interconnected system where different parts can influence each other, and the interrelationships determine system outcomes. An alternative, less-common, assessment approach is to measure skills directly by providing a scenario about an unstructured problem and …

Go to article

Pcl And Dmso2 Composites For Bio-Scaffold Materials, Jae-Won Jang, Kyung-Eun Min, Cheolhee Kim, Chien Wern, Sung Yi Mar 2023

Pcl And Dmso2 Composites For Bio-Scaffold Materials, Jae-Won Jang, Kyung-Eun Min, Cheolhee Kim, Chien Wern, Sung Yi

Mechanical and Materials Engineering Faculty Publications and Presentations

Polycaprolactone (PCL) has been one of the most popular biomaterials in tissue engineering due to its relatively low melting temperature, excellent thermal stability, and cost-effectiveness. However, its low cell attraction, low elastic modulus, and long-term degradation time have limited its application in a wide range of scaffold studies. Dimethyl sulfone (DMSO2) is a stable and non-hazardous organosulfur compound with low viscosity and high surface tension. PCL and DMSO2 composites may overcome the limitations of PCL as a biomaterial and tailor the properties of biocomposites. In this study, PCL and DMSO2 composites were investigated as a new bio-scaffold material to increase …

Go to article

Granite Staters Split On Parental Bill Of Rights; Housing Most Important Problem Facing State 3/21/2023, Unh Survey Center Mar 2023

Granite Staters Split On Parental Bill Of Rights; Housing Most Important Problem Facing State 3/21/2023, Unh Survey Center

All UNH Survey Center Polls

New Hampshire residents are divided in supporting proposed “Parental Bill of Rights” legislation. However, most Granite Staters agree with some rights included in the legislation, including the right for parents to consent to all medical treatments for their child, inspection of educational materials, and to know if their child identifies as a different name or gender at school. A slim plurality oppose a separate proposal to ban gender-affirmative care for minors in the state. One-third of Granite Staters say that housing is the most important problem facing the state, an all-time high. Chris Sununu is still viewed positively as governor.

Go to article

Federal Clerkships: The Inside Scoop, New York Law School Mar 2023

Federal Clerkships: The Inside Scoop, New York Law School

Academic and Bar Success Initiatives

No abstract provided.

Go to article

Authenticity In The Workplace, The Christian Legal Society, The Jewish Law Students Association, The Muslim Law Students Association, The Student Bar Association Mar 2023

Authenticity In The Workplace, The Christian Legal Society, The Jewish Law Students Association, The Muslim Law Students Association, The Student Bar Association

Student Organizations

March 21, 2023

Go to article

Steering Minutes 03/21/2023, Steering Committee Mar 2023

Steering Minutes 03/21/2023, Steering Committee

Steering Committee

No abstract provided.

Go to article

Managing Citations: Secrets To Research Success, Elizabeth Suelzer Mar 2023

Managing Citations: Secrets To Research Success, Elizabeth Suelzer

All Other Contributions

No abstract provided.

Go to article

After-School Programs: Impact On The Academic Outcomes Of Elementary Students In A Rural School, Jeremy Brent Hogan Mar 2023

After-School Programs: Impact On The Academic Outcomes Of Elementary Students In A Rural School, Jeremy Brent Hogan

Doctoral Dissertations and Projects

The purpose of this quantitative, causal-comparative study was to determine if there is a difference in academic achievement between first-, second-, and third-grade students who attended a 21st Century Community Learning Center after-school program and first-, second-, and third-grade students who did not attend a 21st Century Community Learning Center after-school program. There is limited research investigating the effect of after-school programs on the academic achievement of students from rural school settings. Offering quality after-school programs in rural communities is important to meet the needs of students and families and promote positive academic and social outcomes. The sample (N=1062) included …

Go to article

Elementary Teachers' Experiences Of Student Engagement During Forced Virtual Learning: A Phenomenological Approach, Heather Nicole Campbell Mar 2023

Elementary Teachers' Experiences Of Student Engagement During Forced Virtual Learning: A Phenomenological Approach, Heather Nicole Campbell

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand and describe Virginia's Shenandoah Valley Elementary School teachers' experiences of student engagement during forced virtual learning. Teachers' experiences were defined by their positive or negative perceptions of virtual learning experiences. Bandura's social learning theory guided this study on the importance of student engagement in the classroom. This qualitative, transcendental phenomenological study included 12 elementary school teachers from the Madre school division. Data were collected through interviews, letter writing, and focus groups. The precoding and coding processes were used for data analysis to identify three final themes. The themes were online …

Go to article

The Lived Experiences Of First-Time Homeschool Guardians In The Southeastern Region Of The United States During The Covid-19 Pandemic: A Transcendental Phenomenological Study, Mary E. Higgins Mar 2023

The Lived Experiences Of First-Time Homeschool Guardians In The Southeastern Region Of The United States During The Covid-19 Pandemic: A Transcendental Phenomenological Study, Mary E. Higgins

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the motivation of first-time homeschool guardians who began homeschooling during the coronavirus disease 2019 (COVID-19) pandemic in the southeastern region of the United States. The central research question is: What motivated first-time homeschool guardians in the southeastern region of the United States to homeschool their children during the COVID-19 pandemic? David C. McClelland’s motivational needs theory framed this study as it asserted individuals must satisfy four needs: achievement, affiliation, power, and avoidance. The relationship between McClelland’s theory and this study was the motivating factor behind the homeschool guardians’ decisions. This …

Go to article

Who Is Leading Today’S Family? The Detrimental Effects Of An Absent Father, Kimberly J. Davis Mar 2023

Who Is Leading Today’S Family? The Detrimental Effects Of An Absent Father, Kimberly J. Davis

Doctoral Dissertations and Projects

Fathers have an enormous role in their families – it was God’s original design. This study considered the detrimental effects of a physically absent father as the leader, mentor, disciplinarian, and husband of the family home, using a quantitative research design. The theoretical framework used for this descriptive design was John Bowlby’s attachment theory, Dr. Murray Bowen’s family systems theory, Daniel Goleman’s psychological theory on emotional intelligence, and, last, Albert Bandura’s view on aggression theory and the General Aggression Model (GAM). Additionally, the concept of father hunger was explored and measured as this was a crucial construct during this study. …

Go to article

Public School Teachers' Experiences With High-Stakes Testing: A Transcendental Phenomenological Study, Lamorris Nakita Smith Mar 2023

Public School Teachers' Experiences With High-Stakes Testing: A Transcendental Phenomenological Study, Lamorris Nakita Smith

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to examine how public school elementary teachers perceive high-stakes testing situations as it relates to the impact of test anxiety on young children. Bandura’s (1997) social cognitive theory guided this study as it sought to explain the role of human self-belief in cognition, motivation, and behavior. Eleven teachers who are elementary teachers within a North Carolina public school system, have been teaching at least three years, and have administered high-stakes testing over the course of their teaching careers shared their lived experiences of high-stakes testing through their answers to the following: How …

Go to article

Underrepresentation Of Minority Students In Higher Level High School Classes In The Low Country Of South Carolina: A Case Study, Lori Thomas Mar 2023

Underrepresentation Of Minority Students In Higher Level High School Classes In The Low Country Of South Carolina: A Case Study, Lori Thomas

Doctoral Dissertations and Projects

The purpose of this qualitative multiple-case study is to explore the process and the experiences of teachers in recommending minority students for advanced placement (AP) and honors-level high school classes. The theory guiding this study was the invitational theory introduced by Purkey (1978). The invitational theory focuses on the phenomenon that learning is enhanced when people are encouraged to participate or invited into an educational experience. This case study was set in three high schools in a suburban school district in the Low Country of South Carolina and explored the experiences of 12 teachers with the recommendation process. Data collection …

Go to article

Early Shame, Self-Esteem, And Christian Women, Teneka Guyrue Miles Mar 2023

Early Shame, Self-Esteem, And Christian Women, Teneka Guyrue Miles

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to gain a deeper understanding of the lived experiences surrounding the self-esteem of evangelical Christian women with early shame experiences. The theory guiding this study was attachment theory as it explains self-esteem being rooted in early childhood through trust building, unconditional love, and security. The theoretical framework further illustrates the impact of self-esteem as life progresses due to a combination of positive and negative self-evaluations. Early shame experiences affect one’s self-esteem adversely. Low self-esteem could breed isolation once people fail to see their self-worthy in establishing meaningful connections, without which individuals lack the …

Go to article

The Effects Of Secure, Ambivalent, And Avoidant Attachment Styles On Number Of Codependent Behaviors And Relationship Satisfaction, Brittany Nicole Collins Mar 2023

The Effects Of Secure, Ambivalent, And Avoidant Attachment Styles On Number Of Codependent Behaviors And Relationship Satisfaction, Brittany Nicole Collins

Doctoral Dissertations and Projects

Attachment is an important area of study within psychology as individuals learn how to attach and connect with others from childhood into adulthood. An individual’s attachment to parents and caregivers can impact how the individual is able to attach, connect, and trust others in relationships with friends and romantic partners. These attachment styles can impact an individual’s ability to connect and trust in romantic relationships. Examining secure, ambivalent, and avoidant styles; codependent behaviors; and relationship satisfaction is important as codependency continues to be a growing concern, causing unhealthy relationship patterns to develop. Fifty adult participants were recruited from Facebook groups …

Go to article

The Lived Experiences Of First-Generation Black Male Graduates Who Participated In A Black Male Initiative Program, Rah'shad Ra'hyim Bryant Mar 2023

The Lived Experiences Of First-Generation Black Male Graduates Who Participated In A Black Male Initiative Program, Rah'shad Ra'hyim Bryant

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand the lived experiences of first-generation Black male graduates who participated in a Black male initiative in the Southeast region of the United States. The theory guiding this study is Astin’s theory of student involvement. In support of the theory guiding this study, the central research question for the study is What are the lived experiences of first-generation Black male college graduates who participated in Black male initiatives? This research study will utilize the phenomenological design, which will consist of 10-12 first-generation Black male graduates who were involved in a Black …

Go to article

A Transcendental Phenomenological Study Of Connective Experiences Between Elementary Teachers And Parents In A Virtual Setting, Amy J. R. Truett Mar 2023

A Transcendental Phenomenological Study Of Connective Experiences Between Elementary Teachers And Parents In A Virtual Setting, Amy J. R. Truett

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand how connective experiences are built between elementary teachers and parents in a virtual setting at the ABC school district in the southeastern region of the United States. The theory guiding this study was Siemens’ connectiveness theory, as it explored the students' knowledge impacted by the connective experiences of the network of elementary teachers and parents in accessing their learning and success in the virtual school setting. Three essential research questions focused on the connective experiences between elementary teachers and parents in the virtual setting in the southeastern part of the …

Go to article

Transformative Learning Theory As Applied To Worship Studies, Loueda B. Bleiler Mar 2023

Transformative Learning Theory As Applied To Worship Studies, Loueda B. Bleiler

Doctoral Dissertations and Projects

Despite extensive research regarding the application of Transformative Learning Theory in adult education, there is very little literature promoting applying these principles and practices within Christian Worship Studies. Transformative Learning Theory is an educational theory that researches and promotes perspective-changing teaching and learning. Structured educational opportunities and spiritual development through Christian worship both have the potential to be life-altering events in human experience. In each of these dimensions of learning, the final result may include a change in perspective which then leads to modified behaviors. Transformative change occurs in the life of the learner. This qualitative research study explores the …

Go to article

The Digital Pulpit: Having Church When You Can't Have Church, Joshua W. Hall Mar 2023

The Digital Pulpit: Having Church When You Can't Have Church, Joshua W. Hall

Doctoral Dissertations and Projects

The COVID-19 pandemic presented unique difficulties and challenges across the globe. Churches responded to these challenges in different ways. At Mt. Olivet Baptist Church, where the researcher serves, the physical church buildings were closed and physical worship services suspended in favor of online services. This arrangement persisted for ten weeks. After reopening the physical church building for in-person services, average church attendance had decreased, church giving had increased, and spiritual formation had taken place. This research aimed to address the reason as to why these challenging conditions produced such unexpected results. To achieve this, the researcher utilized a series of …

Go to article

High Health Care Cost In The U.S. And Its Impact On An African American Church Community In East Orange, New Jersey, William Charles Mar 2023

High Health Care Cost In The U.S. And Its Impact On An African American Church Community In East Orange, New Jersey, William Charles

Doctoral Dissertations and Projects

Access to affordable quality health care has been a long debating issue in the United States. Many scholarly research articles indicated that the cost of insurance premiums, deductibles, co-payments, and prescription drugs continue to rise every year. Despite various efforts to reduce the cost of health care in the United States, the trend remains the same. Au contraire, more Americans are unable to afford the cost of prescription drugs. More Americans postpone their medical treatments. More Americans find it difficult to financially address their health care needs. It can be inferred that high health cost has a significant impact in …

Go to article

Understanding Workplace Conditions Contributing To Physician Burnout Prevalence In Maryland State, Fatima Adefunke Queen Mar 2023

Understanding Workplace Conditions Contributing To Physician Burnout Prevalence In Maryland State, Fatima Adefunke Queen

Doctoral Dissertations and Projects

Physician burnout is a three-dimensional work-related response to prolonged and unresolved stress. The prevalence of up to 50 percent is higher among primary care providers in the U.S. and is a significant healthcare problem. This qualitative multiple-case study explored workplace conditions contributing to physician burnout in Maryland State. In a purposive sample, the researcher interviewed twenty-one (21) physicians comprised of Medical Doctors (M.D.), Doctors of Nursing Practitioners (DNPs), and Nurse Practitioners (NP). The Shanafelt's well-being framework was applied to understand physician burnout, workplace conditions, and attrition. Data was collected and analyzed using semi-structured interviews and literature. Five themes analyzed are: …

Go to article

A Case Study: Exploring High School Extracurricular Activities' Sponsors' And Coaches' Experiences With The Inclusion Of Ninth--Grade Students As A Marginalized Population, Kimberly Swaney Mar 2023

A Case Study: Exploring High School Extracurricular Activities' Sponsors' And Coaches' Experiences With The Inclusion Of Ninth--Grade Students As A Marginalized Population, Kimberly Swaney

Doctoral Dissertations and Projects

The purpose of this case study was to explore the inclusion process for extracurricular activity sponsors and coaches at a rural high school in southwestern Pennsylvania. The theory guiding this study was Maslow’s theory of human motivation as it provided a structural format that was useful for implementing an inclusive process into extracurricular activities. This was a qualitative, single case study with a purposeful sampling of 11 participants representative of extracurricular activity sponsors and coaches in a rural school district. The central research question was: How do high school extracurricular activities’ sponsors and coaches describe their experiences with the inclusion …

Go to article

First Prev Next Last