Digital Commons Network^™

A Meta-Narrative Review: Efficacy Of Non-Invasive Prenatal Testing (Nipt) In The Detection Of Sex Chromosomal Aneuploidy In Singleton Pregnancy, Tien T. Dao, Arianna Fields, Annie Huynh, Nikkita Mcghee, Christian Pellegrini

Research Methods Poster Session 2023

Abstract:

Objective: To assess the efficacy of Noninvasive Prenatal Testing (NIPT) as a screening method for Sex Chromosomal Aneuploidy (SCA) and its application in clinical practice.

Methods: Searches on Pubmed and M.D. Anderson Cancer Center Research Medical Library was performed to identify primary research articles published between January 2018 to April 2023.

Results: The average combined SCA's PPV was 46.08%. The average PPV for 45, X, 47, XXX, 47, XXY, and 47, XYY was 26.05%, 44.82%, 50.21%, and 62.99%, respectively. The average PPV for 46, XY was 1.18%; however, there is a lack of statistical data for 46, XY. NIPT …

A Meta-Narrative Review Of Runx1-Runx1t1 And Its Relativity To Cbf Disruption Within The Adult Population, Duong Do, Alma Guerrero, Fatima Osorio Guzman, Robert Hernandez, Aml Ibrahim, Andrea Nguyen

Research Methods Poster Session 2023

Acute Myeloid Leukemia (AML) is an aggressive subgroup of leukemias developed from a deviant hematopoietic stem cell, prevented from differentiating into a mature cell. Additionally, core binding factor (CBF) is disrupted by the translocation of chromosomes 8 and 21. This balanced translocation generates the RUNX1-RUNX1T1 fusion gene on the derivative chromosome 8, resulting in t(8;21)(q22;q22.1). These events cause a blockage of hematopoietic stem cell differentiation and ultimately lead to leukemia transformation (Beghini, A. 2019). Using Fluorescence in situ hybridization (FISH) and Karyotyping, molecular translocation can be detected, visualized, and associated with chromosomes 8 and 21 [t(8;21)(q22;q22)]. Furthermore, this study will …

Interactions Between Metabolism And Growth Can Determine The Co-Existence Of Staphylococcus Aureus And Pseudomonas Aeruginosa, Camryn Pajon, Marla C. Fortoul, Gabriela Diaz-Tang, Estefania Marin Meneses, Ariane R. Kalifa, Elinor Sevy, Taniya Mariah, Brandon Toscan, Maili Marcelin, Daniella M. Hernandez, Melissa M. Marzouk, Allison J. Lopatkin, Omar T. Eldakar, Robert Smith

Biology Faculty Articles

Most bacteria exist and interact within polymicrobial communities. These interactions produce unique compounds, increase virulence and augment antibiotic resistance. One community associated with negative healthcare outcomes consists of Pseudomonas aeruginosa and Staphylococcus aureus. When co-cultured, virulence factors secreted by P. aeruginosa reduce metabolism and growth in S. aureus. When grown in vitro, this allows P. aeruginosa to drive S. aureus toward extinction. However, when found in vivo, both species can co-exist. Previous work has noted that this may be due to altered gene expression or mutations. However, little is known about how the growth environment could influence the …

Clemson Board Of Trustee Minutes, Research And Economic Development Committee, 2023 April 20, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Finance And Facilities Committee, 2023 April 20, Clemson University Board Of Trustees

Minutes

No abstract provided.

Optimal Method For Reconstructing Polychromatic Maps From Broadband Observations With An Aysmmetric Antenna Pattern, Brianna Cantrall, Emory F. Bunn, Solomon Quinn

Honors Theses

Broadband time-ordered data obtained from telescopes with a wavelength-dependent, asymmetric beam pattern can be used to extract maps at multiple wavelengths from a single scan. This technique is especially useful when collecting data on cosmic phenomena such as the Cosmic Microwave Background (CMB) radiation, as it provides the ability to separate the CMB signal from foreground contaminants. We develop a method to determine the optimal linear combinations of wavelengths (“colors”) that can be reconstructed for a given telescope design and the number of colors that are measurable with high signal-to-noise ratio. The optimal colors are found as eigenvectors of a …

Length Bias Estimation Of Small Businesses Lifetime, Simeng Li

Honors Theses

Small businesses, particularly restaurants, play a crucial role in the economy by generating employment opportunities, boosting tourism, and contributing to the local economy. However, accurately estimating their lifetimes can be challenging due to the presence of length bias, which occurs when the likelihood of sampling any particular restaurant's closure is influenced by its duration in operation. To address the issue, this study conducts goodness-of-fit tests on exponential/gamma family distributions and employs the Kaplan-Meier method to more accurately estimate the average lifetime of restaurants in Carytown. By providing insights into the challenges of estimating the lifetimes of small businesses, this study …

Elementary School Parent Perceptions Of “Critical Race Theory” In The Curriculum, Helen Wallace

Honors Theses

Critical Race Theory (CRT) implementations within educational settings is a controversial and polarizing concept in the American political climate. Many Americans are strongly opposed to the idea of CRT within the classroom due to a misguided belief that children have no idea what race or racism is until it is taught to them explicitly. On the other hand, proponents of CRT argue that teaching children to ignore race further perpetuates racial discrimination and prevents children from adequately understanding racial injustice. There is currently a lack of research investigating perceptions of CRT implementations in education among parents. This research aimed to …

Clemson Board Of Trustee Minutes, Executive And Audit Committee, 2023 April 20, Clemson University Board Of Trustees

Minutes

No abstract provided.

An Exploration Of The Experience Of Leisure Among Adults Who Immigrated To The United States From Latin American Countries, Violeta Chavez Serrano, Jazminne Orozco Arteaga, Karen Mccarthy

Spring 2023 Virtual OTD Capstone Symposium

Kaplan (1975) defined leisure as a self determined activity that is pleasant and allows for personal growth. Although the diversity among the population in the United States has continued to increase over the past years (United States Census Bureau, 2019) the amount of leisure research related to race and ethnicity is relatively limited. According to Floyd et al., (2008) only 4.5% of published articles highlighted the impact of race and ethnicity on leisure. Exploring how personal context influences occupational engagement, by examining a specific group's experience engaging in an occupation can help further develop the understanding of how personal factors …

Grasping Opportunities Of Digital Technology And Digital Economy, Consistently Improving Urban Science Research, Guangtao Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Influencing Factors And Mechanism Of China’S Technology Supply Security, Jiasu Lei, Jie Jiao

Bulletin of Chinese Academy of Sciences (Chinese Version)

At present, the economy in China is changing from high speed growth in the past few years to high quality development, which raises higher requirements for the security of technical supply. This study defines the concept and connotation of technology supply security, and analyzes the influencing factors of technology supply security as well as the formation mechanism of technology supply “insecurity”. In order to improve the security of technology supply, we must adhere to the basic idea of high level science and technology self-reliance, improve the system of relay research institutions and its cohesive mechanism, and clarify the ideas and …

Accelerating Efforts To Improve Policy System To Support Basic Research In Enterprises, Ke Wen, Ningning Zhang, Zhenguo Li, Dingyi You

Bulletin of Chinese Academy of Sciences (Chinese Version)

Enterprises are the principal players of scientific research and technology innovation. Increasing the participation of enterprises in basic research is of great significance for China to realize high-level self-reliance and strength in science and technology and to improve the efficiency of national innovation system. However, there is still an obvious gap between the basic research capabilities of Chinese enterprises and those of the United States, Japan, or other developed countries. In this study, we firstly reviewed the characteristics and problems of Chinese enterprises’ basic research, finding that expenditure on basic research in enterprises accounts for a relatively low proportion of …

Disciplinary System, Academic System And Discourse System Of Technological Sciences, Zhongkai Yang, Deming Lin, Yongxia Liang

Bulletin of Chinese Academy of Sciences (Chinese Version)

In 1957, Tsien Hsue-shen published an article entitled “On the Technological Sciences” in Chinese Science Bulletin, which laid the foundation for the research of technological sciences in China. However, in the following 60 years, the thought of technological sciences failed to receive stable attention and support. It was not until 2021 when General Secretary Xi Jinping made another important statement at the 20th Academician Conference of the Chinese Academy of Sciences, the 15th Academician Conference of the Chinese Academy of Engineering, and the 10th National Congress of the China Association for Science and Technology that technological sciences had entered into …

From Policy Promotion To Research Output: Brief Analysis Of Technical Challenges Of Hospital-Led Artificial Intelligence Research, Yu Zhuang, Cheng Zhou

Bulletin of Chinese Academy of Sciences (Chinese Version)

In recent years, artificial intelligence has become a key direction of medical and health-related research and a hot spot of international competition. In order to investigate the current situation and challenges in hospital-led artificial intelligence researched, this study selects 14 national pilot hospitals to promote the high-quality development of public hospitals as samples, adopts a combination of quantitative and qualitative methods, analyzes the research articles related to artificial intelligence published by the sample hospitals in recent years, and analyzes the technical challenges in the hospital-led artificial intelligence research. The results show that although the number of hospital-led artificial intelligence research …

Policy Overview (March, 2023)

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Cover 2

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

2023 Issue 4 Content

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Sustainable Diets: Improving Planetary And Population Health (Evidence Summary For Policymakers), C Pettinger

School of Health Professions

No abstract provided.

The Libraries And Student Success, Jennifer Mayer

University Libraries Publications

Requested presentation on how the UNC University Libraries contribute to student academic success.

All Cheers, University Of Dayton

Materials from the University of Dayton Magazine Website

The University announces its first comprehensive campaign in 20 years.

Connection For Success, Michelle Tedford

Materials from the University of Dayton Magazine Website

Lisa Rich-Milan ’85 was disappointed in UD. And then she saw a change on campus — and an opportunity to help students, today and beyond.

Dayton Diary: Marycrest Nights, Taryn Mitchell

Materials from the University of Dayton Magazine Website

A student remembers her first year — and fire alarms — fondly.

Flyer Time: 4:02 P.M., Ud Arena, Nick Thompson

Materials from the University of Dayton Magazine Website

It's not game day at UD Arena without Red Scare.

Our Ud: How We Grow, University Of Dayton

Materials from the University of Dayton Magazine Website

Life on the University of Dayton campus helps students grow within and beyond the classroom

Our Ud: How We Learn, University Of Dayton

Materials from the University of Dayton Magazine Website

A University of Dayton education, in the Marianist tradition, adapts to the signs of the time.

Dayton Diary: Bear Wrestling, Nick Thompson

Materials from the University of Dayton Magazine Website

A student discovers a long-ago moment that even his Flyer parents didn't know about.

Brittney Isom Graduate Recital, Arkansas State University Department Of Music

Performance Programs

No abstract provided.

Perfusion Pressure-Flow Relationships In Synthetic Poroelastic Vocal Fold Models, Cooper B. Thacker

Theses and Dissertations

The purpose of this research was to study perfusion pressure-flow relationships in self-oscillating synthetic poroelastic vocal fold (VF) models before, during, and after vibration. This was accomplished by developing a custom ultra-soft poroelastic material, incorporating the poroelastic material as the cover layer in a synthetic VF model, and studying the model vibratory response and the flow rate of fluid perfused through the cover layer while undergoing flow-induced vibration. The custom ultra-soft poroelastic material was developed using the method of direct templating with sucrose spheres as the sacrificial template and silicone as the infiltration medium. The average modulus of elasticity of …

A Game Theoretical Approach To Optimal Pitch Sequencing, William Melville

Theses and Dissertations

This paper presents a game theoretical solution to the difficult challenge of optimal pitch sequencing. We model the batter/pitcher matchup as a zero-sum game and determine the equilibrium strategy for both the pitcher and batter. We conclude that the Stackelberg equilibrium and our newly defined decision point equilibrium serve as effective pitch sequencing strategies.