Digital Commons Network^™

Viola Mccrae

African American Funeral Programs

No abstract provided.

Roy Dufrain Oral History Interview, Roy Dufrain, Lorenzo Spaccarelli

Raymond College

No abstract provided.

Review Of Cardiovascular Risk Of Androgen Deprivation Therapy And The Influence Of Race In Men With Prostate Cancer, James Fradin, Felix J. Kim, Grace Lu-Yao, Eugene Storozynsky, William K. Kelly

Department of Medical Oncology Faculty Papers

Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke. This review summarizes the available research on the cardiovascular risk of men using androgen deprivation therapy. We also discuss racial disparities surrounding both prostate cancer and cardiovascular disease, emphasizing the importance of biological/molecular and socioeconomic factors in assessing baseline risk in patients beginning androgen ablation. Based on the literature, we provide recommendations for monitoring patients who are at high risk for a cardiovascular adverse event while being treated on androgen …

The Potential Regulation Of A-To-I Rna Editing On Genes In Parkinson's Disease, Sijia Wu, Qiuping Xue, Xinyu Qin, Xiaoming Wu, Pora Kim, Jacqueline Chyr, Xiaobo Zhou, Liyu Huang

Faculty, Staff and Student Publications

Parkinson's disease (PD) is characterized by dopaminergic neurodegeneration and an abnormal accumulation of α-synuclein aggregates. A number of genetic factors have been shown to increase the risk of PD. Exploring the underlying molecular mechanisms that mediate PD's transcriptomic diversity can help us understand neurodegenerative pathogenesis. In this study, we identified 9897 A-to-I RNA editing events associated with 6286 genes across 372 PD patients. Of them, 72 RNA editing events altered miRNA binding sites and this may directly affect miRNA regulations of their host genes. However, RNA editing effects on the miRNA regulation of genes are more complex. They can (1) …

Sintesis Dan Karakterisasi (3-Aminopropil)-Trimetoksisilan Terkonjugasi Asam Folat Untuk Fungsionalisasi Nanopartikel, Retna Putri Fauzia, Husein H. Bahti

Chimica et Natura Acta

Asam folat diketahui memiliki afinitas yang cukup tinggi pada reseptor folat (Kd=10-10) yang diekspresikan berlebih di permukaan sel-sel kanker tertentu (seperti sel kanker ovarium dan serviks). Oleh karena, itu asam folat sering digunakan sebagai suatu pentarget aktif untuk membawa obat atau dalam hal ini nanopartikel, sehingga secara spesifik menuju sel kanker yang diinginkan, baik untuk tujuan diagnosis maupun penyembuhan penyakit kanker. Pada penelitian ini, asam folat akan dikonjugasikan pada aminopropyl trimetoksisilan (APTMS) melalui pembentukan N-hidroksisuksinimida (NHS) ester asam folat (NHS-FA) terlebih dahulu dan selanjutnya direaksikan dengan APTMS melalui pendekatan reaksi 1-etil-3-(3- dimetilaminopropil) karbodiimida (EDC) dan NHS (EDC/NHS) Ester. APTMS termodifikasi …

Biosintesis Zno Nanopartikel-Ctab Dari Ekstrak Air Daun Jambu Biji, Ion Zn2+ Dan Ctab: Karakterisasi Dan Aplikasinya Sebagai Antibakteri Escherichia Coli, Ahmad Fatoni, Ema Ratna Sari, Julia Ningsi, Nurlisa Hidayati

Chimica et Natura Acta

Biosintesis ZnO nanopartikel-CTAB dilakukan dalam suasana basa dengan interaksi antara ion Zn2+ , CTAB dan media ekstrak air daun jambu biji. Tujuan dari penelitian ini adalah biosintesis ZnO nanopartikelCTAB, karakterisasi dan aplikasinya sebagai antibakteri. Karakterisasi produk ini dengan spektrofotometer FTIR dan XRD. Suspensi ZnO nanopartikel-CTAB digunakan sebagai antibakteri Escherichia coli dengan metode difusi sumuran. Gugus fungsi Zn-O muncul pada bilangan gelombang 486,06 cm-1 dan ukuran kristalinitas ZnO nanopartikel-CTAB diperkirakan sebesar 10,08 nm. Rata-rata zona hambat ZnO nanopartikel - CTAB terhadap Escherichia coli pada setiap konsentrasi adalah 9,10 -10,70 mm.

Analisis Potensi Antioksidan Daun Kayu Bulan (Pisonia Alba Span.) Sebagai Agen Anti Penuaan Dini, Rizqa Salsabila Firdausia, Kholif Sholehah Indra Kurniasih, Agnes Diani Nirwaningtyas, Rita Rusmeilina

Chimica et Natura Acta

Penuaan merupakan suatu proses alamiah yang dapat dipengaruhi oleh radikal bebas. Adanya radikal bebas dapat dicegah oleh agen antioksidan. Salah satu tanaman hias yang diketahui mengandung fenolik dan flavonoid serta aktivitas antioksidan yaitu daun kayu bulan (Pisonia alba S). Berdasarkan penelusuran pustaka, belum terdapat penelitian yang membandingkan aktivitas antioksidan daun kayu bulan dengan metode DPPH, FRAP dan ABTS. Penelitian ini dilakukan dengan tujuan mengetahui potensi daun kayu bulan sebagai agen anti penuaan dini melalui analisis kemampuan antioksidan dengan metode DPPH, FRAP dan ABTS. Penelitian dilakukan dengan mengekstraksi daun kayu bulan dengan metode maserasi. Ekstrak kental yang diperoleh diuji antioksidan dengan …

Bio-Hand Sanitizer Based On Peel Of Lime (Citrus Aurantifolia S) And Leaves Betel (Piper Betle L), Nila Tanyela Berghuis, Kumara Dimas Setiawan, Angelica Maratu, Pusfianty Pusfianty, Tasya Amanda, Roehanul Janah, Revita Sari

Chimica et Natura Acta

The large number of antiseptic products on the market provide choices for people to choose alcoholic or non-alcoholic hand sanitizers. Most commercial hand sanitizers are 70% to 90% alcohol-based. For some people, the use of alcohol-based hand sanitizers is not friendly for sensitive skin. Therefore, in this study efforts were made to minimize the use of alcohol as an antiseptic agent in hand sanitizers by using lime peel extract and betel leaf extract. Betel leaves contain chemicals that are useful as antiseptic, antibacterial, and antioxidant substances. The lime peel contains flavonoid compounds that are useful as antioxidants, antiseptics, anticancer, anti-inflammatory, …

Extraction And Determination Of Total Phenolic And Flavonoid In Kapok Leaves (Ceiba Pentandra L.) Using Ethanol As Solvent, Dewi Nofita, Renatalia Fika, Neri Fadjria, Arfiandi Arfiandi

Chimica et Natura Acta

Kapok (Ceiba pentandra L.) is traditionally used in medicine. Based on the phytochemical screening, the leaves contain phenolic compounds, including flavonoids and tannins. The method used to determine the total phenol content was the Folin-Ciocalteu method using gallic acid as standard solution. The linear regression equation obtained on measured at 765 nm is y = 0.0054x + 0.0272 with determination (r) and correlation coefficient (R2 ) of 0.9994 and 0.9997. Total phenolic content in ethanol extracts is 89.185 µg/ml calculated as gallic acid. Meanwhile, determination of flavonoid content used comparison standard of quercetin used the AlCl3 method. Measuring at a …

Studi Perbandingan Metode Fragment Molecular Orbital (Fmo) Dengan Mekanika Kuantum Konvensional Serta Pengaruh Solvasi Air Implisit Dan Eksplisit Pada Sistem Yang Tersusun Dari Natrium, Emas, Dan Sitrat, Regaputra Satria Janitra, Rukiah Rukiah, Muhammad Yusuf

Chimica et Natura Acta

Mempelajari interaksi biomolekul-partikel nano emas (AuNP) penting dilakukan untuk mengeksplorasi potensi pemanfaatan AuNP pada bidang diagnostik dan terapeutik. Interaksi biomolekul-AuNP melibatkan interaksi elektrostatik dan transfer muatan dari gugus fungsi nukleofil ke AuNP, maka mempelajari interaksi biomolekul-AuNP dibutuhkan metode mekanika kuantum. Fragment molecular orbital (FMO) merupakan pendekatan mekanika kuantum dengan waktu perhitungan lebih cepat daripada mekanika kuantum konvensional, khususnya untuk sistem yang tersusun dari banyak atom. Interaksi biomolekul-AuNP dapat dipelajari melalui pair interaction energy decomposition analysis (PIEDA) yang diperoleh dari perhitungan FMO. Penelitian ini bertujuan untuk melihat kesesuaian antara hasil perhitungan FMO dengan mekanika kuantum konvensional pada sistem yang tersusun dari …

Ecological Impacts Of Invasive Crayfish In A Naïve Riparian System, Gregor L. Hamilton

Biology ETDs

Aquatic and riparian food webs are inextricably linked. In deserts, they provide critical energy subsidies to surrounding terrestrial food webs, but these vital subsidies are not guaranteed; streams in arid lands are especially sensitive to perturbations. In this dissertation, I investigated the role of an oft-cited threat to stream communities in the lower Colorado River basin: non-native crayfish. I contributed to methodologies in passive integrated transponder use and length-weight relationships in crayfish to aid future research. I leveraged stable isotope analysis of δ¹⁵N, δ¹³C, and δ²H to understand crayfish role in the food webs. …

Assessing The Impact Of A Csforall Research-Practice Partnership Using The Prosper Framework: A Case Study Of The Chicago Alliance For Equity In Computer Science (Cafécs), Erin Henrick, Steven Mcgee, Ronald I. Greenberg, Dale Reed, Don Yanek, Lucia Dettori, Haley Williamson

Computer Science: Faculty Publications and Other Works

The Chicago Alliance for Equity in Computer Science (CAFÉCS) Research Practice Partnership (RPP) has been working for more than a decade towards their mission to engage in research and development that enables Chicago Public Schools (CPS) to ensure that all students in Chicago participate in engaging, relevant, and rigorous computing experiences, increase opportunities for all students to pursue computing pathways and prepare all students for the future of work. The partnership engaged in an iterative design process to develop a framework for understanding the areas of RPP impact on a district. This paper applies the PROSPER framework to the CAFÉCS …

A New Data Integration Framework For Covid-19 Social Media Information, Lauren Ansell, Valle L Dalla

School of Engineering, Computing and Mathematics

The Covid-19 pandemic presents a serious threat to people’s health, resulting in over 250 million confirmed cases and over 5 million deaths globally. To reduce the burden on national health care systems and to mitigate the effects of the outbreak, accurate modelling and forecasting methods for short- and long-term health demand are needed to inform government interventions aiming at curbing the pandemic. Current research on Covid-19 is typically based on a single source of information, specifically on structured historical pandemic data. Other studies are exclusively focused on unstructured online retrieved insights, such as data available from social media. However, the …

Brain Deficit Patterns Of Metabolic Illnesses Overlap With Those For Major Depressive Disorder: A New Metric Of Brain Metabolic Disease, Kathryn S Hatch, Si Gao, Yizhou Ma, Alessandro Russo, Neda Jahanshad, Paul M Thompson, Bhim M Adhikari, Heather Bruce, Andrew Van Der Vaart, Aristeidis Sotiras, Mark D Kvarta, Thomas E Nichols, Lianne Schmaal, L Elliot Hong, Peter Kochunov

Faculty, Staff and Student Publications

Metabolic illnesses (MET) are detrimental to brain integrity and are common comorbidities in patients with mental illnesses, including major depressive disorder (MDD). We quantified effects of MET on standard regional brain morphometric measures from 3D brain MRI as well as diffusion MRI in a large sample of UK BioBank participants. The pattern of regional effect sizes of MET in non-psychiatric UKBB subjects was significantly correlated with the spatial profile of regional effects reported by the largest meta-analyses in MDD but not in bipolar disorder, schizophrenia or Alzheimer's disease. We used a regional vulnerability index (RVI) for MET (RVI-MET) to measure …

Novel Functionalized Spiro [Indoline-3,5'-Pyrroline]-2,2'Dione Derivatives: Synthesis, Characterization, Drug-Likeness, Adme, And Anticancer Potential, Mohd Asif, Sahir Sultan Alvi, Tazeen Azaz, Abdul Rahman Khan, Bhoopendra Tiwari, Bilal B. Hafeez, Malik Nasibullah

School of Medicine Publications

A highly stereo-selective, one-pot, multicomponent method was chosen to synthesize the novel functionalized 1, 3-cycloaddition spirooxindoles (SOXs) (4a-4h). Synthesized SOXs were analyzed for their drug-likeness and ADME parameters and screened for their anticancer activity. Our molecular docking analysis revealed that among all derivatives of SOXs (4a-4h), 4a has a substantial binding affinity (∆G) -6.65, -6.55, -8.73, and -7.27 Kcal/mol with CD-44, EGFR, AKR1D1, and HER-2, respectively. A functional study demonstrated that SOX 4a has a substantial impact on human cancer cell phenotypes exhibiting abnormality in cytoplasmic and nuclear architecture as well as …

Utilizing Robust Design To Optimize Composite Bioadhesive For Promoting Dermal Wound Repair, Rattapol Pinnaratip, Zhongtian Zhang, Ariana Smies, Pegah Kord Forooshani, Xiaoqing Tang, Rupak Rajachar, Bruce Lee

Michigan Tech Publications, Part 1

Catechol-modified bioadhesives generate hydrogen peroxide (H2O2) during the process of curing. A robust design experiment was utilized to tune the H2O2 release profile and adhesive performance of a catechol-modified polyethylene glycol (PEG) containing silica particles (SiP). An L9 orthogonal array was used to determine the relative contributions of four factors (the PEG architecture, PEG concentration, phosphate-buffered saline (PBS) concentration, and SiP concentration) at three factor levels to the performance of the composite adhesive. The PEG architecture and SiP wt% contributed the most to the variation in the results associated with the H2O2 release profile, as both factors affected the crosslinking …

Simultaneous Inhibition Of Thrombosis And Inflammation Is Beneficial In Treating Acute Myocardial Infarction, Ian Vargas, Ryan P Grabau, Junjie Chen, Carla Weinheimer, Attila Kovacs, William Dominguez-Viqueira, Adam Mitchell, Samuel A Wickline, Hua Pan

2020-Current year OA Pubs

Myocardial ischemia reperfusion injury (IRI) in acute coronary syndromes is a condition in which ischemic/hypoxic injury to cells subtended by the occluded vessel continues despite successful resolution of the thrombotic obstruction. For decades, most efforts to attenuate IRI have focused on interdicting singular molecular targets or pathways, but none have successfully transitioned to clinical use. In this work, we investigate a nanoparticle-based therapeutic strategy for profound but local thrombin inhibition that may simultaneously mitigate both thrombosis and inflammatory signaling pathways to limit myocardial IRI. Perfluorocarbon nanoparticles (PFC NP) were covalently coupled with an irreversible thrombin inhibitor, PPACK (Phe[D]-Pro-Arg-Chloromethylketone), and delivered …

Brain Deficit Patterns Of Metabolic Illnesses Overlap With Those For Major Depressive Disorder: A New Metric Of Brain Metabolic Disease, Kathryn S Hatch, Si Gao, Yizhou Ma, Alessandro Russo, Neda Jahanshad, Paul M Thompson, Bhim M Adhikari, Heather Bruce, Andrew Van Der Vaart, Aristeidis Sotiras, Mark D Kvarta, Thomas E Nichols, Lianne Schmaal, L Elliot Hong, Peter Kochunov

2020-Current year OA Pubs

Metabolic illnesses (MET) are detrimental to brain integrity and are common comorbidities in patients with mental illnesses, including major depressive disorder (MDD). We quantified effects of MET on standard regional brain morphometric measures from 3D brain MRI as well as diffusion MRI in a large sample of UK BioBank participants. The pattern of regional effect sizes of MET in non-psychiatric UKBB subjects was significantly correlated with the spatial profile of regional effects reported by the largest meta-analyses in MDD but not in bipolar disorder, schizophrenia or Alzheimer's disease. We used a regional vulnerability index (RVI) for MET (RVI-MET) to measure …

Senior Recital: Antonia Tapias, Violin; Lu Witzig, Piano; April 15, 2023, Antonia Tapias, Lu Witzig

School of Music Programs

Kemp Recital Hall
April 15, 2023
Saturday Evening
9:00 p.m.

Popper Day Concert, April 15, 2023, Illinois State University School Of Music

School of Music Programs

Kemp Recital Hall
April 15, 2023
Saturday Afternoon
5:00 p.m.

Music Student Multicultural Association’S Music And Disability Convocation, April 15, 2023, Illinois State University School Of Music

School of Music Programs

Center for Performing Arts
April 15, 2023
Saturday Afternoon
1:00 pm – 6:00 pm

Senior Recital: Britney Hopkins, Soprano; Joohee Jeong, Piano; Mason Boore, Trumpet; April 15, 2023, Britney Hopkins, Joohee Jeong, Mason Boore

School of Music Programs

Kemp Recital Hall
April 15, 2023
Saturday Afternoon
3:00 p.m.

Graduate Recital: Christopher Brandt, Percussion; April 15, 2023, Christopher Brandt

School of Music Programs

Kemp Recital Hall
April 15, 2023
Saturday Morning
11:30 a.m.

Senior Recital: Michael Jeszke, Saxophone; Lu Witzig, Piano; April 15, 2023, Michael Jeszke, Lu Witzig

School of Music Programs

Kemp Recital Hall
April 15, 2023
Saturday Evening
7:30 pm

2022 Annual Population Report Tables (April 15, 2023), Portland State University. Population Research Center

Oregon Population Estimates and Reports

The population data in the 2022 annual report tables were compiled by the Population Research Center, Portland State University, 4/15/2023.

The tables in this workbook present the 2022 population estimates produced by the Population Research Center, Portland State University. The July 1 estimates of total population for counties and cities and towns were certified December 15, 2022.

Some tables include the U.S. Census Bureau's decennial Census counts and historical population estimates produced by our Center, and other tables include calculations of change since Census 2020. Also included are population estimates for broad age groups and 5-year age groups.

Closing Reading Achievement Gaps For Middle School Students, Michael D. Daugherty

Journal of Educational Research and Practice

This research examined how self-efficacy, collective efficacy, and professional development compared between core content and special education middle school teachers working with middle school students in reading comprehension and fluency. Accordingly, no statistically significant difference in teacher self-efficacy between core content and special education teachers was discovered based on the ANOVA analysis results. An analysis of professional development and collective teacher efficacy showed mixed results with a negative relationship predicted between increased professional development hours for core content teachers. A predicted positive relationship existed with the number of professional development hours increasing for special education teachers. There was no statistically …

Volume 9 Full Text, Bjur Staff

Butler Journal of Undergraduate Research

No abstract provided.

Air Temperature And Diet Are Not Associated With Oxygen Consumption Rate In Banded Crickets, Gryllodes Sigillatus, Nicole Bailey, Connor Oakes, Rachel Sleeth, Mallorie Smith

Butler Journal of Undergraduate Research

All living organisms acclimate to their environments, with ectothermic species particularly susceptible to environmental change, specifically temperature. Ectothermic insects like crickets directly alter their physiological processes depending on the environment in which they live. Temperature is vital in regulating processes such as metabolism, respiration, and reproduction, among other things. What remains unclear is how a change in the environment, specifically extreme temperature change and dietary alterations, affects physiological processes. In this study, we performed experiments on ectothermic banded crickets to examine the effects of temperature change and the interaction of temperature and diet on oxygen consumption. For both experiments, we …

Effects Of Anthropogenic Noise On Body Mass In Gryllodes Sigillatus, Jessica L. Venturi, Joyce Zheng

Butler Journal of Undergraduate Research

Insects use vibrational structures to produce and sense airborne sounds in intraspecific communication. These signals are important in courtship as well as defensive behavior against predators. For example, insects can detect the presence of nearby predators using vibrations. With an increase in anthropogenic activity, processing these signals and the constant threat they represent may increase stress on insects, subsequently affecting their behavior and physiology. Our experiment was designed to determine whether anthropogenic noise, possibly perceived as a stressor, will decrease the body mass of banded crickets, Gryllodes sigillatus. We predicted that the anthropogenic noise would stress the crickets, leading to …

Truth, Not Accuracy: Native American Fiction Vs. White Settler Colonialism, Charles Democker

Butler Journal of Undergraduate Research

For centuries, depictions of Native American culture have largely been constructed by White authors and have thus reflected white settler colonialist ideology. This paper suggests that one way to counter this point of view when studying Native American history is to turn to fiction, specifically fiction written by Indigenous authors. Taking as an example Ojibwe author Louise Erdrich’s Plague of Doves, a novel based on the real-life massacre of a frontier family in the late nineteenth century, this paper argues that the creative fiction of Indigenous authors can counter the biased, incomplete, and often incorrect official histories of White–Native interactions. …