Digital Commons Network^™

A Global Federated Real-World Data And Analytics Platform For Research, Matvey B. Palchuk, Jack W. London, David Perez-Rey, Zuzanna J. Drebert, Jessamine P. Winer-Jones, Courtney N. Thompson, John Esposito, Brecht Claerhout

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

Objective

This article describes a scalable, performant, sustainable global network of electronic health record data for biomedical and clinical research. Materials and Methods

TriNetX has created a technology platform characterized by a conservative security and governance model that facilitates collaboration and cooperation between industry participants, such as pharmaceutical companies and contract research organizations, and academic and community-based healthcare organizations (HCOs). HCOs participate on the network in return for access to a suite of analytics capabilities, large networks of de-identified data, and more sponsored trial opportunities. Industry participants provide the financial resources to support, expand, and improve the technology platform in …

Zoning And City Revenues: Does Euclidean Zoning Impact Cities' Tax Revenues?, Jett Robert Meek

Honors College Theses

This paper is primarily concerned with measuring the impact of zoning for single family residential on city tax revenues within the San Francisco Bay Area. Single family residential zoning acts as a form of Euclidean zoning by restricting zoned land to one type or use. In the wake of decisions of cities such as Minneapolis to end zoning for single family housing, there has been a push for more research into the possible impacts going forward. This paper takes cross-sectional data from 2020 for 101 cities within the Bay Area. To estimate the impact of zoning on city tax revenues, …

Copper Chelation Via Beta-Alanine Extends Lifespan In A C. Elegans Model Of Alzheimer’S Disease, Arnulfo Pulido, Benjamin Hulbert, Hayleigh Giese, Sabrina Kurian, Rebbeca Rozhon, Michael Zambrano, Oscar Diaz, Mariam Abd, Madison Caputo, Daniel S. Kissel, Mallory A. Havens

Biology Department Faculty Articles

The leading hypothesis for Alzheimer’s Disease (AD) has traditionally focused on the aggregation of Amyloid-β into amyloid plaques. However, research has yet to definitively prove the role of the amyloid peptide in the pathology of the disease. Given that all therapeutics targeting amyloid plaques have failed in clinical trials, with one exception, there is a need to explore alternative approaches to treatment of this disease. Therefore, we examined other factors that are altered during AD pathogenesis. Many AD patients have dysregulation of metal ions, such as copper and zinc, in addition to accumulation of Amyloid-β. The interaction between Amyloid-β and …

Grammatical Triples Extraction For The Distant Reading Of Textual Corpora, Stephanie Buongiorno, Stephanie Buongiorno

Multidisciplinary Studies Theses and Dissertations

Grammatical triples extraction has become increasingly important for the analysis of large, textual corpora. By providing insight into the sentence-level linguistic features of a corpus, extracted triples have supported interpretations of some of the most relevant problems of our time. The growing importance of triples extraction for analyzing large corpora has put the quality of extracted triples under new scrutiny, however. Triples outputs are known to have large amounts of erroneous triples. The extraction of erroneous triples poses a risk for understanding a textual corpus because erroneous triples can be nonfactual and even analogous to misinformation. Disciplines such as the …

Landslide Forecast In Taiwan Based On Machine Learning In The Gis Field, Yi Shen

Honors Capstones

Landslides can pose a significant risk to life, property, and infrastructure in mountainous regions, and can be triggered by various factors, including intense rainfall, earthquakes, and water level changes. Machine learning is commonly used to forecast landslides, based on statistical relationships between past landslides and multiple variables to create a general forecasting model. However, these models often require large amounts of data to achieve accurate results. This project aims to use only a few variables but take advantage of both their spatial distribution and temporal trends to improve the accuracy of landslide forecasts. This approach is tested in Taiwan, a …

Cerium Oxide Nanoparticles/Polyacrylonitrile Nanofibers As Impervious Barrier Against Viral Infections, Merna H. Emam, Reham S. Elezaby, Shady Swidan, Samah A. Loutfy, Rania M. Hathout

Pharmacy

Background: Using face masks is one of the protective measures to reduce the transmission rate of coronavirus. Its massive spread necessitates developing safe and effective antiviral masks (filters) applying nanotechnology. Methods: Novel electrospun composites were fabricated by incorporating cerium oxide nanoparticles (CeO2 NPs) into polyacrylonitrile (PAN) electrospun nanofibers that can be used in the future in face masks. The effects of the polymer concentration, applied voltage, and feeding rate during the electrospinning were studied. The electrospun nanofibers were characterized using SEM, XRD, FTIR, and tensile strength testing. The cytotoxic effect of the nanofibers was evaluated in the Vero cell line …

The Elephant In The Garden, Ila France Porcher

Animal Sentience

The other commentators on Chapman & Huffman (2018) have pointed out in different ways that despite our biological nature, there is a widespread tendency for humans to believe that we are not only superior to animals, but that we are not animals at all. Alongside our denial of animal sentience and cognition, this has resulted in the denial of our own instinctive natures. It is this denial that is our error, for it is only by understanding our true natural heritage that we can begin to change the runaway path we are on.

Commencement Program: 2023, Governors State University

Commencement Documents and Videos

Ralph Anthony Sansone and Bhargavi Kasetti delivered the Student Addresses.

Myrna Montgomery performed "Lift Ev'ry Voice and Sing".

Lluvia Hernandez-Aguirre was recognized as the Student Trustee.

Sylvia Puente received the Honorary Doctor of Human Letters Degree.

Addressing The Kentucky (9-12) High School Teacher Shortage Through Correlations Of Teacher Turnover And Working Conditions, Ryan Cowsert

Ed.D. Capstone Reports

Our country is currently experiencing a nationwide teacher shortage that continues to grow as more teachers leave the profession than join it. According to a recent study, 55% of the nation’s teachers are considering leaving the profession. Specifically, in Kentucky, 72% are considered at risk of leaving the profession. National teaching data suggest poor working conditions are the primary reason for teacher turnover (Carver-Thomas & Darling-Hammond, 2017). Therefore, can it be inferred that schools with better working conditions experience less turnover than schools with poorer working conditions? This study was designed to determine the magnitude of correlations between teacher turnover …

Lipoxin A4 (Lxa4) Reduces Alkali-Induced Corneal Inflammation And Neovascularization And Upregulates A Repair Transcriptome, Jiucheng He, Thang L. Pham, Azucena H. Kakazu, Abhilash Ponnath, Khanh V. Do, Haydee E.P. Bazan

School of Graduate Studies Faculty Publications

Purpose: To investigate the anti-inflammatory and anti-angiogenic effects of the bioactive lipid mediator LXA4 on a rat model of severe corneal alkali injury. Methods: To induce a corneal alkali injury in the right eyes of anesthetized Sprague Dawley rats. They were injured with a Φ 4 mm filter paper disc soaked in 1 N NaOH placed on the center of the cornea. After injury, the rats were treated topically with LXA4 (65 ng/20 μL) or vehicle three times a day for 14 days. Corneal opacity, neovascularization (NV), and hyphema were recorded and evaluated in a blind manner. Pro-inflammatory cytokine expression …

2023 Ursinus College Commencement Progam, Ursinus College

Ursinus College Commencement Programs

This Ursinus College Commencement program from 2023 contains the list of speakers and order of events for the day.

The Echo: May 13, 2024, Taylor University

2023-2024 (Volume 111)

No abstract provided.

Neuroinflammatory And Metabolomic Temporal Dynamics From Inhaled Wildfire Smoke With Attenuation Via Pharmacological Intervention, David Scieszka

Biomedical Sciences ETDs

Wildfire smoke is a global issue affecting nearly all humans on the surface of this Earth. Smoke dispersion from wildfires can span continents and cross oceans with amazing ease. Furthermore, total acres of land burned per year in the United States has roughly doubled since 1980, meaning this issue will persist for an indeterminate amount of time. Exposure to wildfire smoke is hazardous and promotes aging-associated events in the cardiopulmonary systems. Yet long- and short-term effects on the brain remain relatively unknown. From these, it is critically important to understand the neurological impacts from wildfire smoke exposure; to compare these …

Mental Health In College Athletes: An Ot Perspective, Olivia Sarik, Lakeisa Boykin, Susan Didino

Spring 2023 Virtual OTD Capstone Symposium

Problem: There is often increased stigma surrounding college athletes in the spotlight, thus preventing them from seeking help with their mental health (Kaier et al., 2015). There are currently no known programs that offer resources specifically for college athletes (Sudano & Miles, 2016). It is important for occupational therapists to advocate for mental health resources for student-athletes to create healthy habits and routines within the athletic environment.

Purpose: The purpose of this capstone was to increase awareness of mental health resources that are available to student-athletes and coaching staff at Baldwin Wallace University to improve mental health in athletics and …

Mechanisim Of Plasmon-Driven Photochemical Reactions, Hamed Kookhaee

Chemistry and Chemical Biology ETDs

Understanding a photocatalytic reaction condition that selectively leads to a desired product on metal surfaces is a longstanding research problem in heterogeneous catalysis. Here, using plasmon enhanced N-demethylation of methylene blue (MB) as model reaction, we show that high degree of product selectivity can be achieved by switching the mechanism from charge transfer to adsorbate electronic excitation and vice versa using surface ligands. In the presence of cetyl trimethyl ammonium bromide (CTAB) surface ligand on gold nanoparticles, MB is selectively transformed to thionine at 633 nm excitation wavelength that overlaps with the electronic transition of the adsorbate. At resonant excitation …

Financial Accounting Case Studies, John A. Batson Jr

Honors Theses

This thesis was completed in the 2021-2022 academic year and is comprised of eleven accounting case studies. The topics from these cases vary widely and are not strictly focused on accounting. Examples of this includes cases done on the twenty-year anniversary of 9/11, the ramifications of COVID-19 on Pfizer, and having to interview a local business owner. We also completed cases concerning the city we wanted to intern in as well as an excel certification course. Following the conclusion of case 5, me and several other honors students worked together to complete the next six cases which involved analyzing International …

An Analysis Of Accounting Concepts Through Case Studies, Molly Medling

Honors Theses

This thesis aims to provide a holistic picture of the accounting profession through various topics in the field. Divided into case studies, each case examines a particular accounting issue or concept through research and analysis. These cases range from an examination of the events of 9/11 through the lens of the accounting profession to a multiple-case analysis of International Paper Company’s financial position and future actions. Several online articles, financial reports, and accounting courses were used to inform the information included in this thesis. These sources were not only used to provide an analysis of accounting concepts, but also to …

Financial Accounting Case Studies, Warren Spence Graves

Honors Theses

This thesis is a collection of eleven accounting case studies completed during the ACCY 420 course, taught by Dr. Victoria Dickinson within the 2021-2022 academic year. These cases cover a wide variety of topics within the scope of accounting, including the ramifications of the terrorist attacks on September 11, 2001, on businesses and the effects COVID-19 had on Pfizer Inc. Other studies completed ranged from examining a city for potential future residence, an interview with a local business owner, and an excel verification course. Case 6 through Case 11 focuses on the analysis of ExxonMobil and its financials, conducted by …

Telepractice-Based Language Intervention Training For Parents Of Children With Autism Spectrum Disorders, Sarah Bryan

Honors Theses

This study closely examined the progression and fidelity of strategy implementation of parents undergoing an ASD language intervention training program. This instructional, interactive program was designed for parents of children with autism, thus catering to the needs of participants involved. This study assessed the use of parent comments and redirects, two kinds of parent strategies, during each parent-child interaction to provide more information about the impact of training sessions. The researchers hypothesized that by the end of training, parent participants would increase their fidelity of strategy implementation, increase their use of comments rather than redirects, and employ more open-ended questions …

At The End Of Life: Conceptualizing Human Dignity And Assisted Suicide Debates In Contemporary Germany, Edith-Marie Green

Honors Theses

As medicine improves and breakthroughs on cures for illnesses formerly thought deadly continue to develop, the global population continues to age. This has introduced new concerns about aging and end-of-life health care. One proposed end-of-life healthcare solution is assisted suicide, although the practice is not without its controversies. The case of assisted suicide in Germany is of particular interest for a variety of reasons, and the practice has not had an easy path there. A series of debates in 2015 led to the practice being banned, but that ban was overturned in 2020 by Germany’s Constitutional Court. While assisted suicide …

An Examination Of The Research Addressing Evidence-Based Communication Approaches For Students With Autism, Sydni Kaye Mcatee

Honors Theses

The meta-analysis examines scholarly articles regarding research on evidence-based communication for students with Autism Spectrum Disorder. More specifically, this research involves different forms of Alternative and Augmentative Communication. This form of communication is used without a voice. A variety of interventions for Manual Signing (MS), Speech Generating Devices (SGD), and Picture Exchange Communication Systems (PECS) are reviewed within the research study. The purpose of this research is to define which evidence-based Alternative and Augmentative Communication (AAC) interventions are most effective for children with Autism. More specifically, determining which form of communication can help lead children to more expressive language and …

Comparing Calculated And Perceived Energy Needs In Collegiate Student-Athletes, Lyndsey T. Reed

Honors Theses

The purpose of this study was to evaluate NCAA student-athletes' level of knowledge related to their energy needs. The participants were 75—42 male and 33 female—NCAA Division I student-athletes enrolled at the University of Mississippi (UM) from a variety of sports. In-person data collection took place at UM Athletics facilities by sports registered dietitians during team talks. The names of the athletes were used to find their pre-existing calculated energy, resting metabolic rate (RMR) and total energy expenditure (TEE) using the Nelson equation and the appropriate activity factor. Questionnaire and RMR/TEE data were analyzed and compared to assess knowledge related …

The Effects Of Calmer On The Quality Of Life In Adults With Level 1 Autism Spectrum Disorder, Madilyn Morris

Honors Theses

Level 1 autism spectrum disorder (ASD) is a high-functioning neurodevelopmental disorder (Hodges et al., 2020; Hosseini & Molla, 2023). Several features of level 1 ASD negatively impact quality of life (QOL), and auditory sensitivity (specifically hyperacusis) is one of the most prevalent and disabling features (Danesh et al., 2015, 2021; Kuiper et al., 2019; Williams et al., 2021). Hyperacusis significantly impacts QOL in the level 1 ASD population, as current hyperacusis treatment strategies often result in various forms of social isolation (Adams et al., 2021; Danesh et al., 2015; Neave-DiToro et al., 2021).

However, Flare Audio markets a product (“Calmer”) …

County-Level Unemployment Dynamics Following The Covid Recession: The Effects Of Ppp Loan Take Up, Preston Antes

Honors Theses

The COVID-19 pandemic caused a nationwide shutdown, dragging the US into a recession. To combat the effects of the pandemic on the economy, Congress created the Paycheck Protection Program (PPP) with the focus of preserving jobs and providing liquidity to small businesses. PPP created low-interest, forgivable business loans with forgiveness tied to a few benchmarks, providing a de facto cash transfer to small businesses. Did PPP preserve jobs? When examining Mississippi, this paper shows that counties with high cyclical unemployment participated more intensely in the program. Furthermore, the research shows that as loan totals grew within a county, local labor …

Development Of Recombinant Varicella-Zoster Virus Vaccines Expressing Sars-Cov-2 Antigens, Cody Wilson

Honors Theses

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) continues to cause infections and deaths around the globe. Since its emergence, scientists have worked diligently to discover and produce vaccines to battle the virus. While they successfully created and distributed vaccines, the vaccines are not without flaw. These vaccines do not grant long term immunity, require multiple booster shots, and have not prevented the emergence of viral variants. In this study, the SARS-CoV-2 receptor binding domain (RBD), which is a key part of the spike protein (S), and nucleocapsid (N) genetic sequences were inserted into the live varicella …

Experimenting With Colors In Music: Making And Breaking Rules In The Butterfly Effect, Chloe King

Honors Theses

The following thesis is a culmination of four years of academic and musical development as a percussionist at the University of Mississippi. It offers a discussion and analysis of my original composition, The Butterfly Effect (2021-2023), exploring the compositional process from preliminary sketches to the finalized score. It also discusses the inspiration for composing an original work, the use of different music theory techniques relevant to an analysis of the work, and comparisons to relevant compositions throughout the history of Western music. The Butterfly Effect experiments with compositional techniques that often depart from established rules of harmony and counterpoint, a …

Scoping Review Of The Best Practices In Drug Courts In The United States, Elise Crumrine, Blakely Camille Culp

Honors Theses

Purpose: Drug courts are reform programs that are utilized in America to reduce the amount of incarcerations due to non violent drug charges. A successful drug court has a high number of graduates and low recidivism rates. To accomplish this, a variety of methods are utilized such as medication assisted therapy (MAT), random and mandatory drug testing, positive reinforcement in the form of words or tangible items, etc. The purpose of our study was to identify the best practices of drug courts, as defined as increased graduation rates and decreased recidivism, so that the findings may be applied in the …

Differences In French Law Pertaining To Refugees From Former Colonies: A Case Study Of North Africa And Indochina, Lauren Bergin

Honors Theses

Colonial relations between colonizer and colonized are an interesting yet often understudied part of the legal field. This thesis will focus on these links within the relationship between France and two of its former colonies: North Africa and Indochina. In order to discover more information on these relationships, I take a historical approach focusing on legal documents, debates, and decrees, both from the French government and international bodies and representatives such as the United Nations High Commissioner for Refugees. The resulting discoveries show that French legal documents were far more concerned with North Africa compared to Indochina, both regarding asylum …

The Effect Of Bike Share Expansion On Bay Area Rapid Transit Ridership, Jacob Holifield

Honors Theses

The transportation sector causes significant negative externalities (collisions and pollution), most of which are caused by cars. As a result, policymakers often seek to reduce reliance on cars and spur demand for alternative modes of transportation. Many urban planners posit that bike sharing could serve to increase public transit ridership by allowing the bike sharing system to feed into the public transit stations, thereby solving first- and last-mile problems and reducing the time cost to access public transit. However, research into the effect of bike sharing on public transit is mixed. This thesis examines the effect of the 2017 expansion …

Understanding How Women Navigated The Fight For Equality During The Second Republic And Transition-Era Spain Through Feminist Literature, Amanda Jeanette Pagoaga

Honors Theses

This paper explores how women navigated the fight for equality during the Second Republic and Transition-era Spain through the lens of feminist literature. Specifically, comparing and analyzing two books, Doble esplendor by Constancia de la Mora (1939) and Crónica del desamor by Rosa Montero (1979). Both books feature women in their thirties who work and explore themes of marriage and romantic love, friendship as a space of freedom, motherhood, working women, and politics against the backdrop of the ever-changing sociopolitical situation in Spain. Through close analysis of these works, the author examines how these women navigate gender roles and societal …