Digital Commons Network^™

Dignity And The Free Press, Erin C. Carroll

Georgetown Law Faculty Publications and Other Works

As American institutions wither and die, those who believe in their importance must reflect and rebuild. One institution worthy of sustained attention is the free press. Divorced from government by design, the press can benefit from efforts to reinvigorate and reinvent it in ways that institutions more directly under the federal government’s thumb cannot. To best undertake these efforts, we need a richer understanding of why a free press is vital. Articulating the values that underlie the need for this institution is necessary not only to build the most robust free press, but also to best exercise our freedoms as …

Functional Heterogeneity In Trophoblast Stem Cells Derived From Recurrent Pregnancy Loss Products Of Conception., Qi Fu, Keisuke Kozai, Xingrao Ke, Joe Varberg, Sheng Xia, Ashley S. Howard, Michael Lydic, Kristin Holoch, Courtney Marsh, Elin Grundberg, Kaela Varberg

Manuscripts, Articles, Book Chapters and Other Papers

Recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages, affects 1-5% of couples attempting to conceive and most frequently occurs between 6 and 8 weeks of gestation, coinciding with critical stages of placental development. Despite this temporal association, placental contributions to RPL pathogenesis remain poorly understood. We hypothesized that trophoblast lineage development, including extravillous trophoblast (EVT) and syncytiotrophoblast (STB) differentiation, are disrupted in RPL. To test this hypothesis, we established and functionally characterized human trophoblast stem (TS) cell lines derived from products of conception (POC) obtained from consenting idiopathic RPL cases. Four TS cell lines were successfully derived …

Regional Variation Of Underlying Kidney Diseases In Children Undergoing Chronic Kidney Replacement Therapy Around The Globe., Dagmara Borzych-Dużałka, Marjolein Bonthuis, Uma Ali, Yok-Chin Yap, Michael Manno, Yihui Zhai, Reyner Loza, Seema Hashmi, Naye Choi, Kenza Soulami, Judith Exantus, Mohamed S. Al Riyami, Sameh Mabrouk, Marbella Ma Angeles, Cristina Zelaya-Camacho, Henny Adriani Puspitasari, Syed Saimul Huque, Francisco Cano, Kar Hui Ng, Sevcan A. Bakkaloğlu, Jerome Harambat, Kitty J. Jager, Bradley A. Warady, Franz Schaefer

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: There is a scarcity of information regarding the distribution of the diseases leading to kidney failure (KF) in children living in the emerging world. We used registry data to provide a global overview of the underlying disease spectrum in children commencing kidney replacement therapy (KRT).

METHODS: We analyzed KF causes among 23,620 children and adolescents commencing maintenance KRT in 80 countries, using data from the IPNA Global KRT Registry (including ESPN/ERA Registry), the International Pediatric Dialysis Network (IPDN), the United States Renal Data System (USRDS), and the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). The analysis considered …

Accelerated Weaning Of Opioids To Reduce Pharmacologic Exposure For Neonatal Opioid Withdrawal Syndrome: A Randomized Clinical Trial., Abbot R. Laptook, Adam Czynski, Rouba Chahine, Rachel G. Greenberg, P Brian Smith, Erica Oliveira, Jenna Gabrio, Barry Eggleston, Abhik Das, Jeannette Lee, Barry Lester, Dave Clark, Michele Walsh, Helen Ko, Clare Campbell Asher, Hayley Friedman, Samuel Gentle, Karishma Rao, Anup Katheria, Kristen Benninger, Sanket Jani, Mark Cody Smith, Akram Khan, Ajay Talati, Shaina Lodhi, Fernando Mena, Amanda England, Prabhu Parimi, Ranjit Kylat, Heidi Harmon, Javed Mannan, Meghan P. Howell, Tanner Wright, Jessica Snowden, Act Now Collaborative

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: To determine if newborns receiving morphine or methadone as the primary pharmacologic treatment for neonatal opioid withdrawal syndrome (NOWS) tolerate and receive fewer days of opioid using an accelerated wean protocol (15% decrements) compared with using a slower wean protocol (10% decrements).

STUDY DESIGN: Newborns ≥36 weeks of gestation receiving morphine or methadone for NOWS were enrolled in a pragmatic blinded, randomized multicenter trial. Newborns underwent protocol-driven weaning with decreasing opioid doses of either 15% or 10% decrements. Weaning was encouraged every 24 hours, and if signs of NOWS worsened, the preceding dose was resumed. To maintain blinding, the …

Leading With Hope: A Clinical Communication Campaign To Promote Partner Hiv Testing In Assisted Partner Notification And Antenatal Care Programs In Uganda., Emily A. Hurley, Violet Gwokyala, Linda Kisaakye Nabitaka, Jolly Beyeza Kashesya, Mercylynn Agasha, Florence Namaganda, Nikolaus Schuetz, J Nalubega Ross, Joseph K B Matovu, Rhoda Wanyenze, Glenn Wagner, Kathy Goggin

Manuscripts, Articles, Book Chapters and Other Papers

Among heterosexual couples in sub-Saharan Africa, fears of relationship dissolution and inability to bear healthy children following an HIV-positive result remain barriers to HIV testing. Recently expanded availability of pre-exposure prophylaxis (PrEP) affords a critical opportunity to promote HIV testing with reassuring communication that highlights use for relationship preservation and healthy childbearing. We aimed to develop a theoretically-grounded communication intervention to promote partner HIV testing within assisted partner notification (APN) and antenatal care (ANC) programs in Uganda. Through an 18-month iterative co-creation process, we developed the HOPE Clinical Communication Campaign (HOPE-CCC) in collaboration with a project advisory board (PAB) of …

Natural Maternal Immunity Protects Neonates From Escherichia Coli Sepsis., Raymond E. Diep, Ujjwal Adhikari, Kubra Gokce Tezel, Giang Pham, Allison R. Burrell, Mary A. Staat, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Kate M. Peters, Mark A. Schembri, Scott H. Saunders, David B. Haslam, John J. Erickson, Susana Chavez-Bueno, Sing Sing Way

Manuscripts, Articles, Book Chapters and Other Papers

Escherichia coli is a leading cause of neonatal sepsis, with infection occurring in approximately one in every 1,000 live births. However, with E. coli colonization beginning soon after birth and defects in neonatal host defence maturation, an alternative consideration is why infection does not occur even more frequently. Here we show that newborn babies with E. coli sepsis have selectively reduced vertically transferred natural antibodies that recognize E. coli, mechanistically explaining their susceptibility to infection. Complementary preclinical studies show that preconceptual intestinal colonization with probiotic E. coli Nissle 1917 (EcN) primes anti-E. coli immunoglobulin G (IgG) antibodies with broad cross-reactivity …

The Effects Of Self-Management On Portion Control Consumption In A Natural Setting, Amber Nicole Lampert

Theses and Dissertations

Obesity is a significant public health concern, with overeating as a primary contributor. Despite national nutrition initiatives, most Americans consume inadequate amounts of fruits and vegetables while exceeding recommended portions of calorie-dense foods. Understanding food groups and recommended portion sizes of each may be a prerequisite skill for a health initiative aimed at weight loss. Given that environmental and behavioral factors influence eating behaviors, Applied Behavior Analysis (ABA) offers an evidence-based framework for improving nutritional habits through self-management interventions. This study examined the effects of self-management components on portion control within a natural eating environment. Four adult participants, one male …

Optimisation Of Photosensitive Recording Materials For Broadband Holographic Optical Elements, Michael Murray

Doctoral

The introduction of broadband (white) LED outdoor lighting has led to significant energy savings. However, this has come at the cost of increased light pollution which has negative impacts both on ecological systems and human health. This light pollution is largely the result of the lack of control measures for the directionality of the light emitted by outdoor LED lighting. The lack of directionality also results in higher energy consumption in order to compensate for the light scattered to the atmosphere and sufficiently illuminate the target area. In this thesis holographic optical elements (HOEs) are proposed as a complementary technology …

Analisis Faktor-Faktor Yang Mempengaruhi Angka Kematian Bayi Di Provinsi Sulawesi Selatan Menggunakan Regresi Komponen Utama, Salwa Zahirah Putri Wijaya, Sitti Sahriman Salam, Nasrah Sirajang, Audia Putri Damatia, Hildayanti Hildayanti

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Angka kematian bayi (AKB), khususnya kematian neonatal, merupakan indikator fundamental dalam menilai kualitas pelayanan kesehatan dan kesejahteraan masyarakat. Penelitian ini dilakukan untuk menganalisis faktor-faktor yang memengaruhi AKB di 24 kabupaten/kota di Provinsi Sulawesi Selatan. Variabel independen yang dikaji mencakup dimensi layanan kesehatan, kondisi sosial ekonomi, pendidikan perempuan, sanitasi, air bersih, dan indikator demografis. Data dianalisis menggunakan metode Regresi Komponen Utama (Principal Component Regression/PCR) untuk menganalisis pengaruh variabel-variabel dengan mempertimbangkan adanya potensi korelasi antar variabel independen, sehingga dihasilkan model yang stabil. Melalui analisis komponen utama, lima komponen berhasil dibentuk yang merepresentasikan 84,21% dari total variasi data. Komponen pertama (PC1) …

Rethinking Covid-19 Tourism Recovery, Anestis Fotiadis, Efstathios Polyzos, Tzung Cheng Huan

All Works

No abstract provided.

Mere Machines: Why Originalism Requires Robotic Judging, Michael Showalter

SMU Law Review Forum

In 1776, Thomas Jefferson argued that judges are “mere machines.” This statement captures founding generation’s conception of the judicial task. From Edward Coke to Montesquieu to William Blackstone to Alexander Hamilton to John Marshall, the founding era’s governing legal tradition taught that judges do no more than mechanically apply the law to reach a case’s correct answer. Judges find the law, the Founders consistently emphasized, they do not choose it.

Under originalism, that original understanding of the Article III judicial power controls how federal judges must adjudicate today. Theorists leveled sustained criticism against the Framers’ beliefs in the twentieth century, …

Historic Patterns Of Growth And Destruction In Nj Seagrass Meadows, Masen Eck

Theses, Dissertations and Culminating Projects

Seagrass meadows are one of the many habitats worldwide under threat from human disturbance and worsening climate conditions. This habitat provides many critical ecosystem services to coastal environments, which is why conserving and restoring seagrass meadows is critical. This study investigates the long-term success and failures from several eelgrass restoration sites in Barnegat Bay, New Jersey. Aerial imagery from multiple years were digitized in ArcGIS to assess restoration trajectories over time. Three of the sites were assessed over a period of twelve years (2012-2023), and one site was assessed twice (2021 and 2023). Results from these time series analyses showed …

Adult Age And The Evaluation Of Moral Judgment, Gianna Derosa-Norena

Theses, Dissertations and Culminating Projects

Moral judgments play an important role in social interactions, intergroup conflicts, and the evaluation of behaviors. Moral Foundations Theory proposes that moral reasoning is grounded in five psychological foundations: authority, loyalty, purity, harm, and fairness. Prior research has shown that individuals form stereotypes about different groups and the moral foundations they prioritize, as well as greatly exaggerate the perceived moral differences between groups. The present study examines adult age differences and the stereotyping of moral foundations by investigating whether individuals accurately perceive moral differences between younger and older adults. Participants (N = 300; 100 participants per perspective condition) completed a …

In Praise Of Antony's Folly: The Triumph Of Foolishness In Shakespeare's Antony And Cleopatra, Michael Anthony Rombola

Theses, Dissertations and Culminating Projects

Antony and Cleopatra has long been regarded as a play about shame. Underlying this reading there have been several assumptions, namely that Antony's shame is justified and that Cleopatra's influence is destructive. These beliefs are rooted largely in the historical treatment of Cleopatra, particularly that of Plutarch, who advanced the view that the Queen of Egypt destroyed a formerly great man. In this paper, I argue that the opposite is true: that Shakespeare's Cleopatra, far from destroying Antony, actually helps to liberate him from the tyranny of Roman expectation. In the course of my analysis, I examine two competing sets …

Corporate Social Responsibility, Prosocial Behavior, And Control, Jennifer Fin

Theses, Dissertations and Culminating Projects

The purpose of this study was to better understand how an organization's prosocial behaviors, Corporate Social Responsibility (CSR), shape an individual member's private, prosocial behavior. This study examined whether an individual’s locus of control (LOC) works as a moderator to shape the CSR-behavior relationship. Participants were recruited through Montclair State University’s SONA pool and assigned into a High CSR, Neutral, or Corporate Social Irresponsibility (CSiR) condition. Each participant completed self-report measures to assess internal LOC before the experimental manipulation. Each participant reviewed a news article to match their CSR condition and then had an opportunity to donate their compensation, which …

Interview Format And Job Pursuit Intention, Pallavi Nimbappa Honkanadavar

Theses, Dissertations and Culminating Projects

This study examined how interview format influences job pursuit intentions (JPI) in the context of increasing use of artificial intelligence (AI) in hiring. Specifically, it compared human-led, AI-led, and AI-assisted scenario interview formats, and tested whether perceived procedural fairness and anticipated interview success mediated these relationships, as well as whether AI familiarity moderated the effects. Preliminary results from a sample of 72 participants indicated that, although the overall effect of interview format on JPI was not statistically significant, the pattern of means suggested highest JPI in human-led interview formats, followed by AI-assisted interviews, and finally completely AI-led interviews. Mediation analyses …

From Learners To Leaders: Informal Learning And Leadership Emergence In The Workplace, Ami Rupesh Shah

Theses, Dissertations and Culminating Projects

This study explored the relationship between informal learning behaviors and leadership emergence in workplace settings while also looking at the moderating roles of occupational self-efficacy and learning climate. Using a correlational, cross-sectional design, data was collected from 361 working professionals through an online survey with 341 being the final sample size. Participants completed validated self-report measures assessing informal learning behaviors, occupational self-efficacy, learning climate, and leadership emergence. Correlational and moderation analyses were performed to test the study hypotheses. Results showed that informal learning behaviors was positively and significantly related to leadership emergence. Moreover, occupational self-efficacy and learning climate both were …

Shape Variation In The Mandible Of The Borophagine Canids And Implications For Predatory Behavior, Benjamin Neavear

Theses, Dissertations and Culminating Projects

The borophagines are an extinct lineage of canids that inhabited North America for more than 20 million years. This group included genera such as Aelurodon, Borophagus, and Epicyon. Borophagines are commonly referred to as “bone-crushing dogs” because their skull morphology converged with that of extant hyenas, predators capable of consuming bone. The purpose of this study was to determine whether convergence was present in the mandible, an anatomical structure strongly correlated with feeding behavior, particularly in the genera Aelurodon and Borophagus. It was hypothesized that most borophagine taxa possessed mandibular shapes similar to those of hyenas. Numerous mandibular characters were …

Words And Phrases That Matter: A Corpus Analysis Of Vocabulary And Phraseological Coverage In Myanmar's High School English Textbooks, Kaung Hla Zan

Theses, Dissertations and Culminating Projects

"Myanmar’s high school education relies on centralized EFL textbooks as the primary source of English input for a significant population of Myanmar youth. Following curriculum reforms aiming for communicative competence, this study provides a corpus-based evaluation of the lexical and phraseological composition of Grades 10 to 12 (high school) textbooks. Using a multi-list approach, this study profiled the textbooks against the New General Service List (NGSL) and the Academic Vocabulary List (AVL) for vocabulary coverage. To determine the frequency and coverage of academic phrases, the textbooks were profiled against three lists of academic bundles identified by Simpson-Vlach and Ellis (2010), …

The Challenge Of Responsible Sovereignty And The Dilemma Of Responsibility To Protect: A Case Study In The Middle East, Mona Shujaieh

Theses, Dissertations and Culminating Projects

This thesis applies the Responsibility to Protect (R2P) framework to examine the evolving relationship between state sovereignty and humanitarian intervention in the modern international system. It develops the concept of “responsible sovereignty” to show how sovereignty has shifted from an absolute principle of non-interference toward a socially constructed and conditional norm increasingly linked to a state’s responsibility to protect its population. By tracing the transition from Westphalian sovereignty to contemporary understandings of sovereignty as responsibility, the study highlights how international norms reshape expectations of state behavior while also generating persistent tensions in practice. Focusing on the Middle East, the thesis …

At The Intersection Of Science And Sustainability: A Qualitative Study Of Food Scientists' Personal And Professional Perspectives, Srushti Parikh

Theses, Dissertations and Culminating Projects

Sustainable food systems require not only technological innovation but a more profound understanding of the professionals involved in the field. Even though the topic of sustainability is currently gaining importance throughout the food industry, the real expertise of food scientists is under-researched. PURPOSE: The purpose of this study is to explore food scientists' perspectives on sustainability, how these perceptions influence the way they pursue their careers, and how they view their impact in the larger sustainability agenda of the food industry. METHODS AND MATERIALS: This study captured detailed insights of 22 food scientists’ perspectives through qualitative methods. Food scientists in …

Creating A "Good Person": Netiquette And Instagram, Melissa S. Danai-Nolder

Theses, Dissertations and Culminating Projects

This project aimed to ask the question, “How does digital etiquette, or netiquette, lead to socialization of self-presentation on Instagram?” I interviewed 15 students classified as "Generation Z" who attend a northeastern university and have an Instagram account. This was done using a convenience sample of participants who were asked to participate in the interview. Done by the convenience of the individuals who were at the location at the time. The results indicate a disconnect between wanting to be seen as a “good person” and the means used to paint this image. Netiquette plays a role in crafting self-presentation, as …

Computational And Molecular Modeling Of Asphaltene Aggregation And The Effect Of Radicals And Nonradicals, Lyla Salyani

Theses, Dissertations and Culminating Projects

Asphaltenes are the heaviest component of crude oil consisting of a wide range of polyaromatic compounds with molar mass in the range of 500-800 g/mol. Asphaltenes tend to aggregate and form nanoclusters which lead to clogged pipelines. Understanding asphaltene aggregation has been a long-standing effort of industry and academia. Such systems are a typical example of systems studied to understand the impact of non-covalent interactions that drive the aggregation. Interactions that can be found to contribute to the stability of these aggregates can be π-π stacking, dispersion forces, and pancake stacking. A small fraction, 3%-4%, of the asphaltenes exist as …

Relationships And Recovery: Social Factors In Alcoholics Recovery, Elizabeth Moe

Theses, Dissertations and Culminating Projects

Introduction. Recovery is a process of change through which individuals improve their overall wellbeing, live self-directed lives, and strive to reach their full potential. In recovering from alcohol and substance use, there are many paths one may take to reach recovery, but engagement with new social circles and communities has been shown to be the most effective. This leads to the research question: what is the role of relationships during alcohol recovery? Methods. This mixed-methods study uses both qualitative and quantitative data. Quantitative data from the National Alcohol Survey was used to compare the effects and perceptions of drinking on …

An Invasion Of The Intimate Sphere: The Manipulation Of Libido Under Totalitarian Regimes, Elyssa Lucero

Theses, Dissertations and Culminating Projects

This paper examines the temporal nature of libidinal control in the totalitarian systems represented in George Orwell’s Nineteen Eighty-Four and Aldous Huxley’s Brave New World. Arguing that the most enduring forms of domination operate through the reorganization of desire, the essay explores how regimes intervene in familial, romantic, and social attachments to redirect affective energy towards the state. Orwell depicts a primitive, reactive phase of control in which attachments are violently ruptured, whereas Huxley imagines an advanced system that operates through preemption, never allowing attachments to form. Drawing on Freud’s theory of redirected libido, Berlant’s theory of Cruel Optimism, Marxist …

Analysis Of Collective Behavior In Living And Nonliving Systems, Kaitlyn Cohan

Theses, Dissertations and Culminating Projects

This thesis aims at understanding the phenomenon of of self-organization in complex dissipative systems, living and nonliving. Dissipative systems are characterized by their search for energy, interactions with their surroundings and the production of entropy, all of which result in the creation of stable structures or patterns, which persist as long as the initial environmental conditions are maintained. The two specific models that we chose to study here are (a) Futbol (or Soccer) and (b) a chemical system involving free-floating menthol crystals floating on a fluid surface to represent nonliving systems. Using experiments and mathematical models, we will try to …

Investigation Of Curing And Degradation Mechanisms In Lead White Oil Paint Systems: Impact Of Methyl Linoleate On Paint Matrix Formation And Solvent Extractability, Andrea Serrano Trujillo

Theses, Dissertations and Culminating Projects

Oil-based paints composed of drying oils and lead-containing pigments undergo complex chemical transformations during curing that influence long-term stability and degradation. Despite centuries of use, the molecular mechanisms governing oxidative polymerization and additive incorporation in lead white oil paint systems remain incompletely understood. This study investigates the role of methyl linoleate, a monoester analog of linoleic acid, in the curing and degradation pathways of lead carbonate and linseed oil paint films. A deep focus was placed on determining whether methyl linoleate becomes chemically integrated into the developing polymeric network or remains as an extractable and unbound component, as this distinction …

Constant Connectivity To Work, Health Behaviors, Physical Symptoms: Exploring Boundary Management Practices That Can Help, Christina Christodoulou

Theses, Dissertations and Culminating Projects

The workday inevitably exposes employees to numerous demands that induce stress reactions. Without sufficient recovery (i.e. returning stress reactions to baseline), individuals risk experiencing chronic psychological, behavioral or physical strains. With the rise of constant connectivity to work, recovery is becoming more of a challenge. However, research on the recovery-related consequences of constant connectivity, particularly its impact on health behaviors and physical health outcomes, remains scarce. To fill this gap in the literature, this research explored the relationship between constant connectivity, boundary management practices, health behaviors, and physical symptoms using a mixed-methods, multi-study design. A mixed methods pilot study (N …

Navigating Faith And Sexuality: Christian Pastors' Experiences In Providing Pastoral Care For Lgbtq+ Youth, Keith I. Raymond

Theses, Dissertations and Culminating Projects

Within the Christian context, religion and sexuality are often cultural factors that shape the identity development of LGBTQ+ youth, with congregational stance (affirming, tolerant, non–affirming) and individual religiosity/spirituality serving as protective or risk factors (Crockett et al., 2018; Raedel et al., 2020; Yarhouse & Sadusky, 2021). Christian pastors’ theology, relational ministry approach, and pastoral skills influence how they engage with and care for queer youth, yet the professional ties between pastors and LGBTQ+ youth remain underrepresented in counseling literature. Guided by queer theory, this qualitative case study examined how Christian pastors understand and navigate pastoral care for LGBTQ+ youth within …

Performative Racial Allyship And Ally Ambivalence: A Qualitative Study, Peter D. Goldie

Theses, Dissertations and Culminating Projects

Racism is rampant in and outside of higher education institutions (HEIs). Preliminary research has found that white allyship--or white people's efforts to dismantle racism by partnering with People of Color--can be beneficial to Black communities when done authentically and in ways that center Black voices, perspectives, and liberatory goals. However, a growing body of scholarship has found that white people seldom show up as allies in meaningful ways. Instead, they frequently resort to performative racial allyship (PRA), or behaviors that are meant to signal solidarity with a marginalized racial group yet are superficial and self-serving. To support effective antiracism efforts, …