Digital Commons Network^™

Natriuretic Peptide Biomarkers In The Imminent Development Of Preeclampsia., Stefanie Marek-Iannucci, Estefania Oliveros, Yevgeniy Brailovsky, Preethi Pirlamarla, Amanda Roman, Indranee Rajapreyar

Division of Cardiology Faculty Papers

Preeclampsia is the most common cause of morbidity and mortality in pregnancy, the incidence being significantly higher in low-income countries with reduced access to health care. Women with preeclampsia are at a higher risk of developing cardiovascular disease with a poorer long-term outcome. Early recognition and treatment are key to improving short- and long-term outcomes. Approximately 3%-5% of pregnant women will develop preeclampsia, with potentially fatal outcomes. Despite ongoing research, the exact pathophysiologic mechanism behind its development remains unclear. In this brief report, we describe the potential role of natriuretic peptides as biomarkers in the imminent development of preeclampsia. In …

Willingness To Prepare For Disasters Among Individuals With Disabilities: An Essential Component For Building Disaster Resiliency, Dean Kyne

Sociology Faculty Publications

This study focuses on exploring the factors influencing individuals’ preparedness for disasters. Drawing upon the protection motivation theory (PMT) and the prototype willingness model (PWM), a conceptual framework was proposed to investigate the determinants of willingness to prepare for disasters and its impact on disaster preparedness. Data was collected through an online survey, involving 377 participants with disabilities and medical special needs residing in the Rio Grande Valley (RGV). The collected data was analyzed using generalized structural equation modeling (GSEM) to examine the associations among the selected study variables. The findings indicate that both coping appraisal and threat appraisal significantly …

Puma (Puma Concolor) Sex Influences Diet In Southwest New Mexico, Kelly M.T. Bernard, Travis W. Perry, Nokubonga Mgqatsa

Western North American Naturalist

Puma (Puma concolor) is a wide-ranging, large felid species, and site-specific research on its diet is important for local management. Like the diets of other large felids, puma diets may differ between sex due to size dimorphism and between seasons due to changes in prey vulnerability and availability. We investigated the influence of sex and season on puma diet in southwest New Mexico in terms of prey species and size categories. Pumas (10 males, 6 females) were tracked with GPS collars for an average of one year per individual between February 2008 and July 2020. Puma location was …

Beyond “Glittering Hope”: Introducing Max Stirner’S Unique Possibilities To Social Work, Erica Fonseca

School of Social Work Faculty Publications and Presentations

Max Stirner (1806-1856) is an iconoclastic 19th-century philosopher who, despite a period of obscurity, has remained somewhat influential – particularly within segments of the anarchist milieu. This conceptual article maintains Stirner’s writing has something to offer social work thinking and practice. Using Stirner’s most influential work, The Ego and Its Own, I will present three of Stirner’s terms: Specters, The Creative Nothing, and Ownness. I conclude with a presentation of three “unique” prospects for social work that draws from Stirner’s anti-teleological and anti-foundationalist approach to liberation.

Mexican Gartersnakes (Thamnophis Eques) Along The Gila River In Southwestern New Mexico, Keith Geluso

Western North American Naturalist

The Mexican gartersnake (Thamnophis eques) is a federally threatened species in the United States, with only a few isolated populations remaining in Arizona and New Mexico. For some populations, only limited knowledge exists regarding their status and natural history; thus, all observations are noteworthy. Along the Gila River in New Mexico, for example, only 2 observations of this species have been published, one in 1883 and one in 1973. Herein, I report on 6 additional observations of Mexican gartersnakes from along the Gila River in southwestern New Mexico. Five individuals were documented in riparian habitats close to or …

Ki-Cook: Clustering Multimodal Cooking Representations Through Knowledge-Infused Learning, Revathy Venkataramanan, Swati Padhee, Saini Rohan Rao, Ronak Kaoshik, Anirudh Sundara Rajan, Amit Sheth

Publications

Cross-modal recipe retrieval has gained prominence due to its ability to retrieve a text representation given an image representation and vice versa. Clustering these recipe representations based on similarity is essential to retrieve relevant information about unknown food images. Existing studies cluster similar recipe representations in the latent space based on class names. Due to inter-class similarity and intraclass variation, associating a recipe with a class name does not provide sufficient knowledge about recipes to determine similarity. However, recipe title, ingredients, and cooking actions provide detailed knowledge about recipes and are a better determinant of similar recipes. In this study, …

Denoising Cough Sound Recordings Using Neural Networks, Laya Jose, Shlomo Berkovsky, Hao Xiong, Cecilia Mascolo, Roneel V. Sharan

Staff Scholarship - Australia & Dubai

Objective cough sound evaluation is useful in the diagnosis and management of respiratory diseases. However, the performance of cough sound analysis models can degrade in the presence of background noises common in everyday environments. This brings forward the need for cough sound denoising. This work utilizes a method for denoising cough sound recordings using signal processing and machine learning techniques, inspired by research in the field of speech enhancement. It uses supervised learning to find a mapping between the noisy and clean spectra of cough sound signals using a fully connected feed-forward neural network. The method is validated on a …

Spatial Variations In Ancient Meteoric Water: An Investigation Of The Rattlesnake Tuff, Julian Michael Cohen

Dissertations and Theses

Volcanic glass has been used extensively as a paleoclimate proxy. Deuterium (²H) concentrations in glass have been found to be stable over geologic timescales, making δD a reliable proxy for ancient water chemistry. However, continued work revolves around better understanding how different factors affect preserved water in ash. Here, I analyze δD in the Rattlesnake Tuff (RST), a widespread ca. 7 Ma ashflow tuff, and create an isoscape to assess variations in δD across Oregon during that time. Additionally, I examine compositional data from glass shards to explore the relationship between δD and shard composition. The RST exhibits …

Wave Optics Approach To Solar Cell Brdf Modeling With Experimental Results, Madilynn Compean, Todd V. Small, Milo W. Hyde Iv, Michael Marciniak

Faculty Publications

Light curve analysis is often used to discern information about satellites in geosynchronous orbits. Solar panels, comprising a large part of the satellite’s body, contribute significantly to these light curves. Historically, theoretical bidirectional reflectance distribution functions (BRDFs) have failed to capture key features in the scattered light from solar panels. In recently published work, a new solar cell BRDF was developed by combining specular microfacet and “two-slit” diffraction terms to capture specular and periodic/array scattering, respectively. This BRDF was experimentally motivated and predicted many features of the solar cell scattered irradiance. However, the experiments that informed the BRDF were limited …

Genetic, Socioenvironmental, Behavioral Contributions To Metabolic Profiles And Body Composition In Samoan Infants, Lacey W. Heinsberg, Ulai T. Fidow, Kendall J. Arslanian, Steven J. Mullett, Erin E. Kershaw, Yvette Conley, Daniel E. Weeks, Stacy G. Wendell, Nicola L. Hawley

Sigma Foundation for Nursing Research Grant Reports

The purpose of this study is to use untargeted metabolomic profiling and pathway discovery to better understand the foundations of variation in adiposity and body composition (e.g., fat mass, lean mass, bone mass, weight-for-age) in the first two years of life.

Front Matter, The Ovid Staff

Ovid

No abstract provided.

Only The Strong Survive: Portrayals Of Battling Ideals Of Masculinity In Stranger Things, Ava Watson

Ovid

No abstract provided.

Family, Legacy, And Death: A Meditation On Westworld, Henry Woodward

Ovid

No abstract provided.

Joker: The Stereotypical Mentally Disabled Villain, Molly Edwards

Ovid

No abstract provided.

This Is The Bad Place: What Dystopian Literature Tells Us About Oppression And Resistance, Mi Thuta

Ovid

No abstract provided.

Distrust And Disparities In Healthcare Among African Americans, Paige Perry

Ovid

No abstract provided.

The Layers Of Indiana’S Public Libraries, Dana Frohberg

Ovid

No abstract provided.

Island, Ava Like

Ovid

No abstract provided.

Golden Girl, Abby Acierto

Ovid

No abstract provided.

One Good Thing, Julia Skiba

Ovid

No abstract provided.

Ndls Communicator: Week Of 07.24.23, Notre Dame Law School

NDLS Communicator

The Latest News

• 2023 Notre Dame Religious Liberty Summit Protecting Religious Liberty in a Rapidly Evolving Society
• ND Law’s Exoneration Justice Clinic hosts two interns from Strathmore Law School in Kenya
• ND Law Dean G. Marcus Cole included on list of Indiana’s most influential leaders
• Bruce Huber was quoted in the Washington Post article, "How a tree dispute between New Jersey neighbors took over the internet."
• Christian Burset wrote a blog post for Yale Journal on Regulation that compares the Major Questions Doctrine to 18th-century approaches to identifying the limits of executive authority.
• Paul Miller, along with Thilo Kuntz from …

Physiologically Relevant Fluid Shear Stress Induced Receptor Conversion In Hormone Receptor-Positive (Hr+) Breast Cancer, Jonathan James Cuccia

LSU Doctoral Dissertations

Breast cancer is the most common type of cancer among all people in the United States as of 2023 and often has devastating impacts on afflicted patients. Although some treatments show great efficacy against primary breast tumors, none have been able to significantly reduce the mortality rate of breast cancer once it has metastasized to distant sites. In primary, hormone receptor-positive (HR+) breast cancers, endocrine therapies are often used as first-line treatments and are generally well-tolerated. However, as the disease progresses, these previously sensitive cancers can become resistant to endocrine therapies and continue proliferating despite them. Therefore, there is a …

Simplified And Highly-Reliable Automated Production Of [8f]Fspg For Clinical Studies, Mai Lin, Robert T Ta, H Charles Manning

Faculty, Staff and Student Publications

Background: (S)-4-(3-18F-Fluoropropyl)-L-Glutamic Acid ([18F]FSPG) is a positron emission tomography (PET) tracer that specifically targets the cystine/glutamate antiporter (xc-), which is frequently overexpressed in cancer and several neurological disorders. Pilot studies examining the dosimetry and biodistribution of [18F]FSPG in healthy volunteers and tumor detection in patients with non-small cell lung cancer, hepatocellular carcinoma, and brain tumors showed promising results. In particular, low background uptake in the brain, lung, liver, and bowel was observed that further leads to excellent imaging contrasts of [18F]FSPG PET. However, reliable production-scale cGMP-compliant automated procedures for [18F]FSPG production are still lacking to further increase the utility and …

Longitudinal Diffusion And Volumetric Kinetics Of Head And Neck Cancer Magnetic Resonance On A 15 T Mr-Linear Accelerator Hybrid System: A Prospective R-Ideal Stage 2a Imaging Biomarker Characterization/Pre-Qualification Study, Joint Head And Neck Radiation Therapy-Mri Development Cooperative, Mr-Linac Consortium Head And Neck Tumor Site Group

Faculty, Staff and Student Publications

Objectives: We aim to characterize the serial quantitative apparent diffusion coefficient (ADC) changes of the target disease volume using diffusion-weighted imaging (DWI) acquired weekly during radiation therapy (RT) on a 1.5 T MR-Linac and correlate these changes with tumor response and oncologic outcomes for head and neck squamous cell carcinoma (HNSCC) patients as part of a programmatic R-IDEAL biomarker characterization effort.

Methods:Thirty patients with HNSCC who received curative-intent RT at MD Anderson Cancer Center, were included. Baseline and weekly MRI were obtained, and various ADC parameters were extracted from the regions of interest (ROIs). Baseline and weekly ADC parameters were …

Rad51c-Xrcc3 Structure And Cancer Patient Mutations Define Dna Replication Roles, Michael A Longo, Sunetra Roy, Yue Chen, Karl-Heinz Tomaszowski, Andrew S Arvai, Rebecca A Boisvert, Caezanne Keshvani, David Schild, Albino Bacolla, Gareth J Williams, John A Tainer, Katharina Schlacher

Faculty, Staff and Student Publications

RAD51C is an enigmatic predisposition gene for breast, ovarian, and prostate cancer. Currently, missing structural and related functional understanding limits patient mutation interpretation to homology-directed repair (HDR) function analysis. Here we report the RAD51C-XRCC3 (CX3) X-ray co-crystal structure with bound ATP analog and define separable RAD51C replication stability roles informed by its three-dimensional structure, assembly, and unappreciated polymerization motif. Mapping of cancer patient mutations as a functional guide confirms ATP-binding matching RAD51 recombinase, yet highlights distinct CX3 interfaces. Analyses of CRISPR/Cas9-edited human cells with RAD51C mutations combined with single-molecule, single-cell and biophysics measurements uncover discrete CX3 regions for DNA replication …

Carbonate Compensation Depth Drives Abyssal Biogeography In The Northeast Pacific, E Simon-Lledó, Dj Amon, G Bribiesca‐Contreras, D Cuvelier, Et Al

School of Biological and Marine Sciences

Abyssal seafloor communities cover more than 60% of Earth’s surface. Despite their great size, abyssal plains extend across modest environmental gradients compared to other marine ecosystems. However, little is known about the patterns and processes regulating biodiversity or potentially delimiting biogeographical boundaries at regional scales in the abyss. Improved macroecological understanding of remote abyssal environments is urgent as threats of widespread anthropogenic disturbance grow in the deep ocean. Here, we use a new, basin-scale dataset to show the existence of clear regional zonation in abyssal communities across the 5,000 km span of the Clarion–Clipperton Zone (northeast Pacific), an area targeted …

Development And Calibration Of The Lmrpm Mid-Breton River Sediment Diversion Gate Operations, Emily E. Fertitta

LSU Master's Theses

With the rate of coastal land loss in Louisiana, the state is looking for innovative ways to help restore and maintain its coastal wetlands. Sediment diversions are going to be constructed along the Lower Mississippi River to mitigate the issues by diverting river water, sediment and nutrients into adjacent wetlands. Since there are currently no real-world applications of sediment diversions, the Lower Mississippi River Physical Model is a beneficial modeling tool to study the impact sediment diversions and relative sea level rise have on the hydraulics and sediment transport processes in the river. The two river sediment diversions on the …

Adam Binder Series (White Trash Warlock, Trailer Park Trickster, & Deadbeat Druid) By David R. Slayton, Phillip Fitzsimmons

Faculty Articles & Research

Book review of the Adam Binder Series by David R. Slayton. Book review by Phillip Fitzsimmons.

Landscape Of Team-Based Care To Manage Hypertension: Results From Two Surveys In Low/Middle-Income Countries, Oluwabunmi Ogungbe, Mark D Huffman, Et Al.

2020-Current year OA Pubs

OBJECTIVES: Team-based care is essential for improving hypertension outcomes in low-resource settings. We assessed perceptions of country representatives and healthcare workers (HCWs) on team-based hypertension care in low/middle-income countries.

DESIGN: Two cross-sectional surveys.

SETTING: The first survey (Country Profile Survey) was conducted in 17 countries and eight in-country regions: Algeria, Bangladesh, Burundi, Chile, China (Beijing, Henan, Shandong), Cuba, Ethiopia, India (Kerala, Madhya Pradesh, Maharashtra, Punjab, Telangana), Nepal, Nigeria, Philippines, Saint Lucia, Sri Lanka, Thailand, Turkey, Uganda and Vietnam. The second survey (HCW Survey) was conducted in four countries: Bangladesh, China, Ethiopia and Nigeria.

PARTICIPANTS: Using convenience sampling, participants for the …

Using Intervention Mapping And Behavior Change Techniques To Develop A Digital Intervention For Self-Management In Stroke: Development Study, Alex W K Wong, Mandy W M Fong, Elizabeth G S Munsell, Christopher L Metts, Sunghoon I Lee, Ginger E Nicol, Olivia Depaul, Stephanie E Tomazin, Katherine J Kaufman, David C Mohr

2020-Current year OA Pubs

BACKGROUND: Digital therapeutics, such as interventions provided via smartphones or the internet, have been proposed as promising solutions to support self-management in persons with chronic conditions. However, the evidence supporting self-management interventions through technology in stroke is scarce, and the intervention development processes are often not well described, creating challenges in explaining why and how the intervention would work.

OBJECTIVE: This study describes a specific use case of using intervention mapping (IM) and the taxonomy of behavior change techniques (BCTs) in designing a digital intervention to manage chronic symptoms and support daily life participation in people after stroke. IM is …