Digital Commons Network^™

Uab Athletics To Hold Fan Fest On Aug. 5 At Legacy Pavilion, Ted Feeley

Browse All News

No abstract provided.

Striped Expression Of Leucine-Rich Repeat Proteins Coordinates Cell Intercalation And Compartment Boundary Formation In The Early Drosophila Embryo, Chloe A. Kuebler, Adam C. Pare

Biological Sciences Faculty Publications and Presentations

Planar polarity is a commonly observed phenomenon in which proteins display a consistent asymmetry in their subcellular localization or activity across the plane of a tissue. During animal development, planar polarity is a fundamental mechanism for coordinating the behaviors of groups of cells to achieve anisotropic tissue remodeling, growth, and organization. Therefore, a primary focus of developmental biology research has been to understand the molecular mechanisms underlying planar polarity in a variety of systems to identify conserved principles of tissue organization. In the early Drosophila embryo, the germband neuroectoderm epithelium rapidly doubles in length along the anterior-posterior axis through a …

The Emergence Of Convergence, Shana M. Sundstrom, David G. Angeler, Jessica G. Ernakovich, Jorge H. Garcia, Joseph A. Hamm, Orville Huntington, Craig R. Allen

Faculty Publications

Science is increasingly a collaborative pursuit. Although the modern scientific enterprise owes much to individuals working at the core of their field, humanity is increasingly confronted by highly complex problems that require the integration of a variety of disciplinary and methodological expertise. In 2016, the U.S. National Science Foundation launched an initiative prioritizing support for convergence research as a means of “solving vexing research problems, in particular, complex problems focusing on societal needs.” We discuss our understanding of the objectives of convergence research and describe in detail the conditions and processes likely to generate successful convergence research. We use our …

A Phase Ii Clinical Trial Of Pembrolizumab Efficacy And Safety In Advanced Renal Medullary Carcinoma, Chijioke Nze, Pavlos Msaouel, Mohamed H Derbala, Bettzy Stephen, Abdulrahman Abonofal, Nizar M Tannir

Faculty, Staff and Student Publications

Background: Renal medullary carcinoma (RMC) is one of most aggressive renal cell carcinomas and novel therapeutic strategies are therefore needed. Recent comprehensive molecular and immune profiling of RMC tissues revealed a highly inflamed phenotype, suggesting the potential therapeutic role for immune checkpoint therapies. We present the first prospective evaluation of an immune checkpoint inhibitor in a cohort of patients with RMC.

Methods: A cohort of patients with locally advanced or metastatic RMC was treated with pembrolizumab 200 mg intravenously every 21 days in a phase II basket trial (ClinicalTrials.gov: NCT02721732). Responses were assessed by irRECIST. Tumor tissues were evaluated …

Rapid Fluvial Remobilization Of Sediments Deposited By The 2021 Chamoli Disaster, Indian Himalaya, Matthew J. Westoby, Stuart A. Dunning, Jonathan L. Carrivick, Thomas J. Coulthard, Kalachand Sain, Amit Kumar, Etienne Berthier, Umesh K. Haritashya, David E. Shean, Mohd Farooq Azam, Kavita Upadhyay, Michele Koppes, Harley R. Mccourt, Dan H. Shugar

School of Geography, Earth and Environmental Sciences

High-magnitude mass flows can have a pervasive geomorphological legacy, yet the short-term response of valley floors to such intense disturbances is poorly known and poses significant observational challenges in unstable landscapes. We combined satellite remote sensing, numerical modeling, and field observations to reconstruct the short-term geomorphological response of river channels directly affected by the 7 February 2021 ice-rock avalanche−debris flow in Chamoli district, Uttarakhand, India. The flow deposited 10.4 ± 1.6 Mm3 of sediment within the first 30 km and in places reset the channel floor to a zero-state condition, requiring complete fluvial re-establishment. In the 12 months post-event, 7.0 …

Did The Bronze Age Deforestation Of Europe Affect Its Climate? A Regional Climate Model Study Using Pollen-Based Land Cover Reconstructions, Gustav Strandberg, Jie Chen, Ralph Fyfe, Erik Kjellström, Johan Lindström, Anneli Poska, Qiong Zhang, Marie José Gaillard

School of Geography, Earth and Environmental Sciences

Abstract. This paper studies the impact of land use and land cover change (LULCC) on the climate around 2500 years ago (2.5 ka), a period of rapid transitions across the European landscape. One global climate model was used to force two regional climate models (RCMs). The RCMs used two land cover descriptions. The first was from a dynamical vegetation model representing potential land cover, and the second was from a land cover description reconstructed from pollen data by statistical interpolation. The two different land covers enable us to study the impact of land cover on climate conditions. Since the difference …

Leveraging Results-Driven Accountability To Improve Academic And Behavioral Outcomes For Students With Disabilities, Lori R. Anderson

Education Theses and Dissertations

The Office of Special Education Programs’ (OSEP’s) vision for Results-Driven Accountability (RDA) is that OSEP will target its work and investments to best support States in improving results for infants, toddlers, children, and youth with disabilities. State Education Agencies (SEAs) are accountable to OSEP regarding Results Driven Accountability reporting and supporting school districts in the process of improving outcomes for students in special populations. RDA is an accountability system to report data to district and campus leaders related to academic achievement, postsecondary readiness, and disproportionate analysis of students who are Bilingual Emergent/English as a Second Language Learners (BE/ESL), experiencing homelessness, …

Health Promotion And Public Health, Tamar Avades, Ashwin Dhanda

Peninsula Medical School

No abstract provided.

Performance Evaluation And Thermal Management Solutions For A Sustainable Microsized Hydrogen-Powered Turbo-Shaft Engine, Nikolai Baranov

Discovery Undergraduate Interdisciplinary Research Internship

Analyzing the aerospace and automotive industries, there is a transition to sustainable energy generation. Aiming to bridge industrial emissions with the worldwide net zero goal by 2050, one widely considered solution for long-range drones and small aircraft is compact turbo-shaft engines combusting clean hydrogen gas to produce shaft work. The small size and energy-dense fuel allow for a universal powerplant with high specific power output that fits a wide variety of existing solutions. One such micro-sized turboshaft internal combustion engine was created to test the potential power output, thermal management, and combustor optimization of the existing stainless steel assembly. The …

Increasing Rye Cover Crop Biomass Production After Corn Residue Removal To Balance Economics And Soil Health, Sabrina J. Ruis, Humberto Blanco-Canqui, Paul J. Jasa, Glen Slater, Richard B. Ferguson

Department of Agronomy and Horticulture: Faculty Publications

Low or variable cover crop (CC) biomass production could limit CC benefits. Longer CC growing periods via late termination could increase CC benefits, especially under limited crop residue return. We studied whether early (2–3 wk before planting)- or late (at planting)-terminated winter rye (Secale cereale L.) CC maintains soil properties, crop yields, and farm income under 0%, 25%, 50%, 75%, and 100% corn (Zea mays L.) residue removal in rainfed and irrigated no-till in the U.S. Great Plains after 6 yr. Early-terminated CCs produced < 1 Mg ha^-1 of biomass while late-terminated CCs averaged 1.6 Mg ha^-1 at the rainfed …

Prevalence, Management And Efficacy Of Treatment In Portal Vein Obstruction After Paediatric Liver Transplantation: Protocol Of The Retrospective International Multicentre Portal Registry., Bader A. Alfares, Hubert P J Van Der Doef, Barbara E. Wildhaber, Thomas Casswall, Greg Nowak, Martin Delle, Denise Aldrian, Valeria Berchtold, Georg F. Vogel, Piotr Kaliciński, Malgorzata Markiewicz-Kijewska, Adam Kolesnik, Jesús Q. Bernabeu, María Mercadal Hally, Mauricio Larrarte K, Paolo Marra, Michela Bravi, Domenico Pinelli, Mureo Kasahara, Seisuke Sakamoto, Hajime Uchida, Vidyadhar Mali, Marion Aw, Stéphanie Franchi-Abella, Emmanuel Gonzales, Florent Guérin, Guillermo Cervio, Julia Minetto, Sergio Sierre, Martin De Santibañes, Victoria Ardiles, Jimmy Walker Uno, Helen Evans, David Duncan, John Mccall, Steffen Hartleif, Ekkehard Sturm, Jai Patel, Marumbo Mtegha, Raj Prasad, Cristina T. Ferreira, Luiza S. Nader, Marco Farina, Catalina Jaramillo, Manuel I. Rodriguez-Davalos, Peter Feola, Amit A. Shah, Phoebe M. Wood, Michael R. Acord, Ryan T. Fischer, Bhargava Mullapudi, Richard J. Hendrickson, Rajeev Khanna, Viniyendra Pamecha, Amar Mukund, Khalid Sharif, Girish Gupte, Simon Mcguirk, Gilda Porta, Marco Spada, Tommaso Alterio, Giuseppe Maggiore, Winita Hardikar, Marisa Beretta, Rudi Dierckx, Ruben H J De Kleine, Reinoud P H Bokkers

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO.

METHODS AND ANALYSIS: The Portal vein Obstruction Revascularisation Therapy After Liver transplantation registry will facilitate an international, retrospective, multicentre, observational study, with 25 centres around the world already actively involved. Paediatric patients (agedyears) with a diagnosed PVO between 1 January 2001 and 1 January 2021 after liver transplantation will be eligible for inclusion. The primary endpoints are …

Rhd Molecular Analysis—From Discovery To Next Generation Sequencing, Tracey E. Madgett, Wajnat A. Tounsi, Amr J. Halawani, Neil D. Avent

School of Biomedical Sciences

This review traces the evolution of RHD genotyping from the very early days of the discovery of Rh polypeptides in 1982, and the pioneering work of the late 1980s and early 1990s that made the whole approach of RH genotyping possible. This work is often overlooked in contemporary Rh literature with citations of reviews being used which often do not give the complete background story. We have attempted to rectify this here. This review focuses primarily on RHD genotyping, primarily because of space constraints not to include RHCE but also because RHD is of greater clinical significance. In Europe many …

A Constructivist Analysis Of China’S Geopolitical Economic Strategy Toward Africa: A Case Of Sino-Tanzanian South-South Cooperation, Azza Bimantara

Global: Jurnal Politik Internasional

This article discusses China’s foreign policy toward African countries by examining Sino-Tanzanian South-South Cooperation (SSC). By utilising a modified, state-centric social constructivism, this study identifies domestic and international realms of China’s normative structure responsible for shaping China’s identities within the international community. It also explains how China can reconcile its competing identities between a Global South and rising great power statuses, which gives China the ability to combine its normative interest (i.e., Global South solidarity) and material interest (i.e., the geopolitical-geoeconomic strategy) into a diverse project of SSC with positive and proactive perception from Tanzania. This study contributes toward the …

Rethinking Resident Perceptions Of Tourism In British Columbia, Canada, Jarrett R. Bachman, Erin Hodgins, Michael W. Lever

ICHRIE Research Reports

This joint academic/practitioner report segments British Columbia, Canada residents to provide destination managers with new ways to better understand resident perceptions of tourism. The data collection was conducted in April and May of 2022 and had a total of 2,265 valid responses. It was also a practical objective to conduct this research in a manner that is repeatable in jurisdictions beyond British Columbia. This report has confirmed five distinct categories of residents’ perceptions toward tourism, including socio-cultural, economic, environmental, job/career, and Indigenous impacts. In addition to the categories of impacts, a cluster analysis has revealed six clusters of residents based …

Building A Community-Academic Partnership To Improve Underrepresented Group Awareness Of Parkinson’S Disease And Research, Danielle N. Larson, Jennifer Adrissi, Madison Lyleroehr, Emily Zivin, Karen Williams, Tanya Simuni

Journal of Health Disparities Research and Practice

BACKGROUND: Members of underrepresented groups (URGs) are more likely to have delays in PD diagnosis and less likely to receive specialized care when compared to non-Hispanic Caucasians. URGs are not proportionately represented in PD clinical research. Barriers to optimal diagnosis and treatment and research participation are multifaceted but include insufficient community knowledge of PD and research.

OBJECTIVES: To establish a community-academic partnership (CAP) for increasing knowledge of Parkinson’s Disease (PD) and research opportunities in underrepresented Chicago communities. Here, we describe the development, structure, and outcomes of this pilot program.

METHODS: The Chicago Movement Coalition (CMC) was established with academic leaders …

Does Using Sofa Score For Ventilator Triage Among Covid 19 Patients Result In Suboptimal Allocation Of Medical Ventilators For The Bipoc Population?, Alexandrea Mp Masocco, Elisabeth Michel, Ebbin Dotson

Journal of Health Disparities Research and Practice

Introduction: Since the COVID-19 pandemic in the United States, Black, and Latinx populations have been disproportionately affected by the COVID-19 pandemic. It can be inferred with high confidence that those most vulnerable are the least likely to receive essential care. Kidney transplant allocation and COVID-19 triage protocols share commonalities in that both protocols involve using multivariate scored criteria with objective and subjective inputs. As such, the similar conclusion in outcomes is concerning. It is worth questioning whether the racial inequalities demonstrated in the COVID-19 pandemic related to access to life-saving ventilators were associated with triage protocols.

Methodology: Using an exploratory …

Perspectives On Flu Vaccination Advertisement Messaging In The Era Of Covid-19: Thematic Analysis Centering Adult Black Voices, Krissy Moehling Geffel, Stephanie N. Christian, Andrea D. Casas, Harika P. Dyer, Tiffany L. Gary-Webb, Hannah E. Hardy, Roderick Harris, Dara D. Mendez

Journal of Health Disparities Research and Practice

Influenza (flu) is an infectious, respiratory disease that causes substantial burden and mortality, and Non-Hispanic Black people experience profound disparities in flu disease burden in the United States. One contributor to flu disease disparities is lower flu vaccination rates among Black populations. This qualitative study was conducted during the COVID-19 pandemic and used the Public Health Critical Race Praxis framework to center and elicit Black adults’ perspectives of desired flu vaccine messaging. This work builds upon efforts to increase access to flu vaccinations and recommendations are provided to aid in tailoring flu vaccine messaging via a health equity lens. Recommendations …

Diabetes Related Distress And Co-Occurrence With Depressive Symptoms In Urban Low-Income African American And Hispanic/Latinx Adults With Type 2 Diabetes, Laurie Ruggiero, Sarah Williams Leng, Mary De Groot, Ben S. Gerber, Rosalba Hernandez, Lauretta Quinn

Journal of Health Disparities Research and Practice

Introduction. Burden of diabetes in the U.S. is greater in racial-ethnic minority populations than non-Hispanic Whites. Depression and diabetes-related distress (DRD) are recognized as relatively common and important psychosocial areas to address in people living with diabetes. Limited research in the U.S. has focused on DRD in racial-ethnic minority populations. The purpose of this study is to describe patterns of DRD and co-occurrence with depressive symptoms in urban low-income African American and Hispanic/Latinx adults with type 2 Diabetes Mellitus (T2DM).

Method. We examined the baseline data collected for a randomized clinical trial (RCT) studying the impact of a culturally tailored …

Supporting Minority Serving Institution Faculty To Enhance Biomedical Research: The Csulb Center For Health Equity Research Institute, Laura H. D'Anna, Thomas Alex Washington, Wendy Nomura

Journal of Health Disparities Research and Practice

Scientists from Minority Serving Institutions (MSIs) bring unique perspectives and experiences that enhance the potential for understanding factors that are associated with racial, ethnic, and social inequities in health and health status. However, inadequate research infrastructure and mentoring opportunities within MSIs limit faculty engagement in the research enterprise. Additionally, structural inequities embedded in the NIH grant funding process disproportionately disadvantage underrepresented minority (URM) faculty and faculty at MSIs. The foci of the intensive Center for Health Equity Research (CHER) Institute were to 1) increase the number of early career faculty members (with an emphasis on MSI faculty) who are better …

Socioeconomic Disparities Exist In Access To Rotator Cuff Repair Surgery, Justin Solarczyk, Heather Roberts Md, Stephanie Wong Md, Derek Ward Md

Journal of Health Disparities Research and Practice

Background: The relationship of socioeconomic disparity in access to rotator cuff repair (RCR) has not been well studied. Socioeconomic, racial, and ethnic disparities in access to surgical management of rotator cuff tears have previously been described in patients with commercial insurance. This study is a population-level analysis which investigates racial and ethnic disparities in access to surgical rotator cuff repair across multiple health insurance statuses.

Purpose: (1) Is non-white race and ethnicity associated with lower rates of RCR? (2) Do these associations change throughout different insurance statuses?

Methods: We used the Healthcare Cost and Utilization Project (HCUP) database to identify …

The Milwaukee Passavant, 1952, V1 N1, December, Advocate Aurora Health

Historical Documents - Combined

Milwaukee Hospital, Milwaukee, WI: Quarterly news bulletin from Milwaukee Hospital. This is the first printed issue and contains a brief history of the hospital, introductions from the hospital administration, and information about Christmas at the hospital.

The Milwaukee Passavant, 1953, V2 N3, September, Advocate Aurora Health

Historical Documents - Combined

Milwaukee Hospital, Milwaukee, WI: Quarterly news bulletin from Milwaukee Hospital. This issue celebrates the 90th anniversary of the hospital and the 50th anniversary of the Milwaukee Hospital School of Nursing. It also includes an obituary of Sister Emma Lerch and histories of the hospital and the nursing school.

The Milwaukee Passavant, 1957, V6 N4, December, Advocate Aurora Health

Historical Documents - Combined

Milwaukee Hospital, Milwaukee, WI: Quarterly news bulletin from Milwaukee Hospital. This issue highlights the Women's Auxiliary and information about Christmas at the hospital.

Milwaukee Passavant, 1961, V10 N1, March, Advocate Aurora Health

Historical Documents - Combined

Milwaukee Hospital, Milwaukee, WI: Quarterly news bulletin from Milwaukee Hospital. This issue includes information from the 1960 Annual report.

Milwaukee Passavant, 1961, V10 N4, December, Advocate Aurora Health

Historical Documents - Combined

Milwaukee Hospital, Milwaukee, WI: Quarterly news bulletin from Milwaukee Hospital. This issue is called "The Roving Reporter" and includes brief information about different areas of the hospital.

The Passavant, 1967-1968, V16 N4, Winter, Advocate Aurora Health

Historical Documents - Combined

Lutheran Hospital of Milwaukee, Milwaukee, WI: Quarterly news bulletin is now called "The Passavant" and is associated with Lutheran Hospital of Milwaukee, Inc. This issue covers the building and construction of the Lutheran Hospital as well as updates from the Women's Auxiliary and photographs from the annual Christmas party.

The Passavant, 1968, V17 N3, Fall, Advocate Aurora Health

Historical Documents - Combined

Lutheran Hospital of Milwaukee, Milwaukee, WI: Quarterly news bulletin from the Lutheran Hospital of Milwaukee, Inc. This issue contains information on the automatic filing equipment, three physicians honored by the American College of Surgeons, the 70th graduating class from the Lutheran Hospital School of Nursing, and one of the nurses modeling new uniforms on a local TV station.

The Passavant, 1969, V18 N1, Spring, Advocate Aurora Health

Historical Documents - Combined

Lutheran Hospital of Milwaukee, Milwaukee, WI: Quarterly news bulletin from the Lutheran Hospital of Milwaukee, Inc. This issue contains the 1968 annual report, an update on new construction, a program with local high school students and the nursing school, and employee recognition.

The Passavant, 1969, V18 N2, Summer, Advocate Aurora Health

Historical Documents - Combined

Lutheran Hospital of Milwaukee, Milwaukee, WI: Quarterly news bulletin from the Lutheran Hospital of Milwaukee, Inc. This issue contains a special report on new heart monitoring equipment, the last capping ceremony in the old chapel before its renovation, a wedding service in the new chapel, a new pastoral education program, and a directory of new fellows.

Cardiovascular Disease In Saudi Arabia: Facts And The Way Forward, Adel Abdulkader Tash, Rasha Fahad Al-Bawardy

Journal of the Saudi Heart Association

While some risk factors for cardiovascular diseases (CVDs) are non-modifiable, other determinants like obesity, hypertension, type-2 diabetes and dyslipidemia can be mitigated by a wide plethora of measures to control CVD morbidity/mortality. Those determinants have been on the rise in Saudi Arabia, exacerbated by sedentary lifestyle. The Saudi Vision 2030 focuses include the reduction of CVD clinical and economic burden to scale-up vitality and longevity; in a new era of comprehensive healthcare. From a health economics standpoint, CVDs entail a burden on healthcare systems directly through expenditure and indirectly through years living with the disease, low productivity, premature morbidity and …