Digital Commons Network^™

Integrated Genomic, Proteomic And Cognitive Assessment Induchenne Muscular Dystrophy Suggest Astrocyte Centric Pathology, Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Pulasthi Dissanayaka, Isuru Gunarathne, Dhammika Amaratunga, Roshan Liyanage, Sunethra Senanayaka, Saraji Wijesekara, Hemal H. Gunasekara, Kamala Vanarsa, Jessica Castillo, Yetrib Hathout, Ashwin Dalal, Harry W.M. Steinbusch, Eric Hoffman, Chandra Mohan, K. Ranil D. De Silva

Pharmacy Faculty Scholarship

Introduction: Documented Duchenne Muscular Dystrophy (DMD) biomarkers are confined to Caucasians and are poor indicators of cognitive difficulties and neuropsychological alterations.

Materials and methods: This study correlates serum protein signatures with cognitive performance in DMD patients of South Asian origin. Study included 25 DMD patients aged 6–16 years. Cognitive profiles were assessed by Wechsler Intelligence Scale for Children. Serum proteome profiling of 1317 proteins was performed in eight DMD patients and eight age-matched healthy volunteers.

Results: Among the several novel observations we report, better cognitive performance in DMD was associated with increased serum levels of MMP9 and FN1 but decreased …

N Y State Dent J August-September 2023

The New York State Dental Journal

In the August-September 2023 issue, the reader will find the following feature articles:

• Iatrogenic Indirect Compression of the Inferior Alveolar Nerve by a Dental Implant
• Use of Dentoalveolar and Zygomatic Implants in Restoration of Maxillary Defect Following Fibula Free-flap Reconstruction Failure
• Flapless Approach to Dental Implant Surgery: To Use or Not to Use?

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Why Reach Codes: Local Players Driving Statewide Building Standards, San Diego Regional Climate Collaborative, Gabriella Medina, Darbi Berry, Gabriela Yamhure

San Diego Regional Climate Collaborative

Reach codes are local energy ordinances that employ various technologies, strategies, and integrated systems that go above California Building Standards Code (CA Building Code, Title 24) standards and support greenhouse gas emission reduction efforts. A reach code is a mandated energy performance requirement for the built environment, typically incorporated as part of a city’s climate action plan, local hazard mitigation plan, or climate adaptation plan. Not only do reach codes help local jurisdictions remain in compliance with state mandates, they enable local climate leadership by signaling support for the future direction of state Building Code standards. This blog provides a …

Volleyball Media Guide 2023, Wofford College. Departmet Of Athletics

Media Guides

No abstract provided.

Distribution And Habitat Associations Of The Georgia Satyr (Neonympha Areolatus) In Arkansas, Kristi Patterson

ATU Theses and Dissertations 2021 - Present

The Georgia satyr (Neonympha areolatus) is a small sedentary butterfly that is rare in Arkansas. Currently, the exact locations of this butterfly in Arkansas are unknown, along with the habitat characteristics associated with their presence. In order to determine these unknowns, I completed 104 surveys across seven different wildlife management areas in southern Arkansas. Pollard-Yates transects were conducted at each study site, and weather variables were recorded before each survey. Vegetation surveys were also completed at each site, and where each Georgia satyr was identified. Generalized linear models (GLM) were created to identify what parameters are important for …

Protecting Wa Crops Issue 32 - August 2023, Department Of Primary Industries And Regional Development, Western Australia

Protecting WA Crops

Protecting WA Crops Issue 32 - August 2023 contents:

• Sclerotinia management for narrow leaf lupins crops
• Meet Crop Protection team member – Ciara Beard

Ua80 Bylaws Revised, W Club

University Organizations

Bylaw revisions made in August 2023.

Equity Fund Monthly Report, August 2023, Bryant University, Archway Investment Fund

Archway Investment Fund

No abstract provided.

Fixed Income Fund Report, August 2023, Bryant University, Archway Investment Fund

Archway Investment Fund

No abstract provided.

"Next Year Is Our Year": An Examination Of Sport Fandom Of Perennial Loser Teams, Ethan Puckett

Masters Theses & Specialist Projects

This study set out to examine the relationships between NFL team success and various fan traits like grit, global and collective self-esteem, team fandom, and sport fandom. The main hypotheses of this study were that fans of perennial loser NFL teams would demonstrate significantly higher levels of grit, sport fandom, and team fandom than fans of more successful teams and significantly lower levels of global and collective self-esteem than fans of more successful fans. Participants were recruited via online forums as well as in person via Western Kentucky University’s Study Board. There were a total of 85 participants, all of …

Behavioral Response To Conspecific Sounds In Loricariid Catfishes (Pterygoplichtys Pardalis And Otocinclus Vittatus), Hephzibah Obafunmiso

Masters Theses & Specialist Projects

Sound production is a means of communication among many fish species. In fishes, sound is produced through various mechanisms, but in the family Loricariidae, known as armored suckermouth catfishes, sound is produced primarily through pectoral fin spine stridulation. Previous experiments have described the sounds produced and shown the mechanism of sound production in two species of loricariid catfishes, Pterygoplichthys gibbiceps and Otocinclus affinis, but the functional significance of loricariid sounds is still unknown. To address this question, I examined the behavioral responses of Pterygoplichthys pardalis and Otocinclus vittatus to conspecific calls. Individual fish (N=10 for P. pardalis) or groups …

A Predictive Flood Model For Urban Karst Groundwater Systems, Trayson Lawler

Masters Theses & Specialist Projects

Urban karst environments are often plagued by groundwater flooding, which occurs when water rises from the subsurface to the surface through the underlying caves and other karst features. The heterogeneity and interconnectedness of karst systems often makes them very unpredictable, especially during intense storm events; urbanization exacerbates the problem with the addition of many impervious surfaces. Residents in such areas are frequently disturbed and financially burdened by the effects of karst groundwater flooding. The Federal Emergency Management Agency (FEMA) offers limited protection to citizens living near flood-prone areas as they primarily focus on the areas near surface bodies of water. …

The Impact Of Beliefs About Emotions On Emotion Regulation & Psychological Health, Sarah Brock

Masters Theses & Specialist Projects

This study examined the effects of different beliefs about emotions (controllability vs. control value) on emotion regulation strategies and psychological health, specifically depression. Little research has examined how different types of beliefs about emotions may interact to impact the emotion regulation strategies they implement, whether that be cognitive reappraisal, expressive suppression, or acceptance. Online questionnaires measuring beliefs about emotion controllability, emotion control values (i.e., whether emotions should be controlled), emotion regulation, psychological health, and coping strategies were completed by 164 participants (117 females; 42 males; 4 non-binary). The participants ranged from 18 to 33 years old. The study found evidence …

A Comparison Of Computational Perfusion Imaging Techniques, Shaharina Shoha

Masters Theses & Specialist Projects

Dynamic contrast agent magnetic resonance perfusion imaging plays a vital role in various medical applications, including tumor grading, distinguishing between tumor types, guiding procedures, and evaluating treatment efficacy. Extracting essential biological parameters, such as cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT), from acquired imaging data is crucial for making critical treatment decisions. However, the accuracy of these parameters can be compromised by the inherent noise and artifacts present in the source images.

This thesis focuses on addressing the challenges associated with parameter estimation in dynamic contrast agent magnetic resonance perfusion imaging. Specifically, we aim …

Utilizing Show Cave Tours To Assess Nonformal Karst Education Outcomes In Youth, Matthew Wisenden

Masters Theses & Specialist Projects

Karst landscapes are regions with geological features such as caves created by the dissolution of predominantly carbonate bedrock. The aesthetic, historical, and ecological significance of karst areas results in human modification of some caves to allow public visitation as ‘show caves.’ While show caves can experience higher levels of anthropogenic degradation than non-commercialized caves, they can also be integral to regional economic, societal, and environmental wellbeing. Moreover, show caves serve as primary platforms for disseminating karst education. School fieldtrips to show caves offer a unique setting for assessing karst-related environmental learning outcomes in children through a nonformal education setting. By …

How Gender Roles Impact The Social Perceptions Of Sexual Assault, Autumn Zwakenberg

Masters Theses & Specialist Projects

This study set out to examine how different factors such as the gender of the victim, the gender of the perpetrator, and the scenario of sexual assault, can influence an outsider’s opinion of the sexual assault. There were two main hypotheses: the first is male and female participants would perceive the push-away scenario as sexual assault at equal rates, but significantly more female participants would perceive the victim allowing the perpetrator to unbuckle their pants scenario as sexual assault. The second is male and female participants would view the male perpetrator scenarios as sexual assault equally, but significantly more female …

Associations Between Parenting Styles & Parental Self-Efficacy, Brian Richards

Masters Theses & Specialist Projects

The purpose of this study was to examine whether there is an association between parenting styles and parental self-efficacy using a United States sample. One hundred twentytwo parents with at least one child between the ages of 5 and 12 years were recruited for the study. Participants were asked to complete a survey with measures for parenting styles and parental self-efficacy as well as demographic information. Results indicated that authoritative parenting style was positively correlated with parental self-efficacy; while authoritarian, permissive, and uninvolved styles were negatively correlated. There is a need to replicate these findings to increase confidence that the …

A Phylogenetic Analysis Of The Leuctra Ferruginea (Walker 1852) Species Group (Plecoptera: Leuctridae), Madison Layer

Masters Theses & Specialist Projects

Leuctra Stephens, 1836 is a genus of Plecoptera (Leuctridae) distributed widely across the Northern Hemisphere, with approximately 210 species reported from eastern North America, Europe, northern Africa, and sporadically across Asia. Eastern North America harbors a small proportion of the global Leuctra fauna (ca. 15% = 31 species), most of which occur in the ancient Appalachian Mountains and unglaciated landscapes in the southeastern USA. Nearctic Leuctra species, except for L. moha and L. crossi, have been divided into five species groups based on external male morphological characteristics. Current phylogenies of Nearctic Leuctra are partial and preliminary, and no comprehensive …

A Robust Model Reduction For The Optimal Boundary Feedback Stabilization Of Magnetizable Piezoelectric Beams, Md Rafi As Sadeq Ibn Emran

Masters Theses & Specialist Projects

The one-dimensional Partial Differential Equation (PDE) model of the wave equation, which describes wave dynamics of a wide-range of controlled mechanical systems, with a state feedback controller at its boundary is known to have exponentially stable solutions. Moreover, it is also reported that the several model reductions of the wave equation by the standard Finite Differences and Finite Elements approximations suffer from the lack of exponential stability (and exact observability without a state feedback controller) uniformly as the discretization parameter tends to zero. This is due to the loss of a uniform gap among the high-frequency eigenvalues as the discretization …

Assessing The Effect Of Reservoirs On Gene Flow In The Southern Two-Lined Salamander (Eurycea Cirrigera), Anna Favalon

Masters Theses & Specialist Projects

Biodiversity is an essential component of natural environmental dynamics. Unfortunately, diversity is threatened by human activities and relies on conservation efforts. An important aspect of biodiversity conservation lies in protecting population connectivity and gene flow. In the mid-1900s, many Kentucky rivers were dammed, creating deep, lentic reservoirs in the valleys once occupied by dynamic, lotic rivers. For species inhabiting the rivers and associated tributaries, the central reservoirs may reduce connectivity among populations and impose a barrier to gene flow. The connectivity of populations on landscapes altered by the creation of reservoirs can be assessed by merging the principles of landscape …

College For What . . . How Middle School Students From Low Socioeconomic Backgrounds Perceived Post-Secondary Education, Michelle Patrick

Dissertations

This study examines the attitudes and perceptions of middle school students from low socioeconomic backgrounds about attending post-secondary institutions. As research continues to explore the experiences of traditional high school students from low socioeconomic backgrounds and students' attendance into post-secondary institutions, research concerning middle school students from low socioeconomic backgrounds preparedness for college attendance has been limited. Using a phenomenological research design to obtain the study's results from fifteen students and thirteen parent interviews provided insight into the “lived experience” of the students’ and parents' attitudes and perceptions regarding college attendance. The study found that regardless of the parents’ and …

New Dentist News (August 2023), Ada Committee On The New Dentist

New Dentist News

New Dentist News offers timely information on scientific, social, educational, political and economic developments affecting new dentists. This collection is historical and items may not reflect current standards. For up-to-date information contact the ADA. The New Dentist News was alternately titled ADA Lifeline, 1997-June 2001.

Enhancing Adherence To Best Practice Guidelines Related To Pressure Injury Prevention In The Operating Room At A Children's Hospital During Comprehensive Dental Procedures., Alyce Bailey Seaver

Doctor of Nursing Practice Papers

Background: 1,600,000 patients develop a hospital-acquired pressure injury every year, and 23% of these originate during surgery. Research has demonstrated that the incidence of hospital-acquired pressure injuries developing during surgery has risen over the past 5 years. This rise has been attributed to nurse circulators exhibiting poor knowledge regarding best practices for intraoperative patient positioning and intraoperative documentation that does not follow standards of care.

Purpose: This quality improvement project aimed to enhance circulator knowledge on best practices for intraoperative patient positioning and improve documentation of intraoperative patient positioning in the electronic medical record to comply with standards of …

Criminal Justice Update - August 2023, Michael Klatt

Criminal Justice Updates

The Criminal Justice Update is a monthly newsletter created by the Adams County Bar Foundation Fellow providing updates in criminal justice policy coming from Pennsylvania's courts and legislature as well as the US Supreme Court.

Contents:

• Updates from PA Governor's Office (no updates this month)
• Updates from the PA Legislature (no updates this month)
• Updates from the Courts
• U.S. Supreme Court (no updates this month)
• PA Supreme Court
• PA Superior Court

2023 Fall - Final Exam Schedule, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

2023 Fall - Schedule Of Classes, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

2023-2024 Academic Calendar, Office Of The Registrar, East Tennessee State University

Academic Calendars

No abstract provided.

August 2023: Center For Academic Achievement, College Of Graduate And Continuing Studies, East Tennessee State University

This and That for Graduate Success Newsletters

No abstract provided.

Dinitroxides In Rapid Scan Electron Paramagnetic Resonance Imaging, Lukas B. Woodcock

Electronic Theses and Dissertations

Local tissue physiology is an important parameter in understanding disease behavior. Rapid Scan (RS) electron paramagnetic resonance (EPR) offers a unique, non-invasive tool for investigation of these so-called microenvironments through EPR Imaging (EPRI). Research into advancement of EPRI falls into many categories. Not least among those are advances in instrumentation and methodology. Presented here are updates to a benchtop EPRI instrument operating at 1 GHz targeted at pre-clinical EPRI applications. Newly developed methods for reducing RS-EPR background through inversion of the magnetic field are also demonstrated. EPR applications are limited in native biological systems due to the miniscule concentration of …

Choosing Sides: Military Behavior In Severely Polarized Democracies, Timothy W. Ford

Electronic Theses and Dissertations

Why does severe polarization result in military intervention in some cases but not others? I argue that the organizational culture unique to a particular military plays a critical role in influencing behavioral outcomes in severely polarized democracies. When faced with sovereign power disputes that arise as a result of severe polarization, military organizations are most likely to develop new strategies of action from the dominant practices, norms, and ideas of military leaders. Severe polarization presents a unique threat to civil-military relations and provides the type of unsettled social periods in which cultural ideologies express an observable influence on military behavior. …