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Rare Diseases In Children—Knowledge, Experiences And Challenges Faced By Pediatricians In Tanzania, Mariam Noorani, Mohamedraza Ebrahim, Francis Furia May 2026

Rare Diseases In Children—Knowledge, Experiences And Challenges Faced By Pediatricians In Tanzania, Mariam Noorani, Mohamedraza Ebrahim, Francis Furia

Paediatrics and Child Health, East Africa

Diagnosing and treating rare diseases in children is a major challenge for pediatricians globally. There is a lack of adequate knowledge of these conditions and diagnostic testing is not easily accessible, which frequently results in delays in care. The knowledge, experiences and challenges faced by pediatricians in Tanzania are not known. This study used a nationwide cross-sectional online survey to describe the knowledge of pediatricians in Tanzania on rare diseases, their experiences, and the challenges they face in treating these children. The survey tool was shared on the Pediatric Association of Tanzania WhatsApp group where most pediatricians are registered. 168 …


A Sharper, Stronger Reality: Rememory In Octavia Butler's Kindred, Rachael E. Vargas May 2026

A Sharper, Stronger Reality: Rememory In Octavia Butler's Kindred, Rachael E. Vargas

Research Papers

This research paper applies epigenetic research and Toni Morrison’s concept of “rememory” to analyze Octavia Butler’s novel, Kindred. This research demonstrates that, through the use of rememory, form, and genre, Butler creates an allegory for epigenetic trauma inheritance within the novel. Dana’s experiences of physical injury disablement serve to exemplify one of the many lived aftermaths of American Chattel Slavery experienced by DACS.


The Epic Work Of Grief: Loss And Narrative Evolution From Classical Epic To Beloved, Marie Manassee May 2026

The Epic Work Of Grief: Loss And Narrative Evolution From Classical Epic To Beloved, Marie Manassee

Yale Divinity School Theses

This thesis examines the evolution of the epic tradition through Virgil’s Aeneid, Dante’s Purgatorio, and Toni Morrison’s Beloved, arguing that grief functions as the central force through which epic form is continually reshaped across historical and cultural contexts. While epic is often associated with heroic conquest, divine destiny, or national foundation, this project contends that the genre is equally structured by acts of loss, mourning, and departure. In the Aeneid, grief becomes the condition of imperial becoming, as Aeneas’s movement toward Rome depends upon the relinquishment of personal attachments and the transformation of loss into historical action. Dante’s Purgatorio inherits …


Ai×Life 2026: Advances In Computational Biology Across Scales For Life & Health Sciences, Suma Mohan S., Devika N. T., Pranavathiyani G. May 2026

Ai×Life 2026: Advances In Computational Biology Across Scales For Life & Health Sciences, Suma Mohan S., Devika N. T., Pranavathiyani G.

Conference Proceedings

Book of Abstracts of the International Conference, AIxLife 2026: Advances in Computational Biology Across Scales for Life & Health Sciences, held on 17–18 April 2026, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, INDIA 

About the Conference

Conventional computational biology laid the foundation for biological data analysis through statistical models, algorithms, and curated databases, enabling insights into genes, proteins, and pathways. Today, the integration of artificial intelligence, spanning machine learning, deep learning, and large language models (LLMs) is driving a transformative shift across biological scales, from atomic and molecular interactions to pathways, cellular systems, organisms, and populations.

AI-powered approaches …


Linking Urban Forest Ecosystem Services With The Sustainable Development Goals: A Bibliometric And Thematic Synthesis (2008–2022), Whisnu Febry Afrianto, Muhammad Ilham May 2026

Linking Urban Forest Ecosystem Services With The Sustainable Development Goals: A Bibliometric And Thematic Synthesis (2008–2022), Whisnu Febry Afrianto, Muhammad Ilham

Jurnal Penelitian Kehutanan Wallacea

Despite growing recognition of urban forests as vital providers of ecosystem services (ES) that support the Sustainable Development Goals (SDGs), existing scientific literature remains fragmented and lacks a comprehensive synthesis. This study addresses that gap through a systematic bibliometric analysis of global research on urban forestry ecosystem services published between 2008 and 2022, encompassing 229 articles. The analysis examined the three main classifications of ecosystem services and all 17 SDGs. Publications on urban forestry ecosystem services have shown a steady increase since 2008, peaking between 2018 and 2022, while citation counts reached their highest point in 2012 and gradually declined …


Species Distribution Modeling Of Parasitic Corpse Flower Rafflesia Arnoldii Var. Arnoldii R. Br Related To Host’S Fractional Photosynthetically Active Radiation In Tanggamus, Sumatra, Indonesia, Andriwibowo Andriwibowo, Suyud Utomo May 2026

Species Distribution Modeling Of Parasitic Corpse Flower Rafflesia Arnoldii Var. Arnoldii R. Br Related To Host’S Fractional Photosynthetically Active Radiation In Tanggamus, Sumatra, Indonesia, Andriwibowo Andriwibowo, Suyud Utomo

Jurnal Penelitian Kehutanan Wallacea

Corpse flower, or scientifically known as Rafflesia arnoldii var. arnoldii R.Br, is one of the species that is endemic to Sumatra, Kalimantan and Java Island. As a parasitic plant, this species depends on its tree host species. While the host species depends on environmental variables include Fractional Photosynthetically Active Radiation (FAPAR), forest covers, and elevation for its growth. Then those variables were important to develop the Species Distribution Modelling (SDM) of R. arnoldii using the MaxEnt technique. One of the important regions for R. arnoldii in Sumatra is Tanggamus in Lampung, and currently, information about suitable habitats for R. arnoldii …


The Status Of The Endangered Rafflesia And Conservation Efforts In Java Island, Indonesia, Bahana Aditya Adnan, Purnomo Purnomo, Suwarno Hadisusanto May 2026

The Status Of The Endangered Rafflesia And Conservation Efforts In Java Island, Indonesia, Bahana Aditya Adnan, Purnomo Purnomo, Suwarno Hadisusanto

Jurnal Penelitian Kehutanan Wallacea

Rafflesia species (Rafflesiaceae) is a small endo-holoparasitic South-East Asian plant genus known for its exceptionally large flowers, rare species, and high island endemism. Three species of Rafflesia, i.e. R. patma, R. rochussenii, and R. zollingeriana, are known from Java, Indonesia. All three species are threatened with extinction due to human activities that cause habitat loss and fragmentation. Our literature review revealed that currently, factors influencing the existence of this genus, including its life cycle and environmental factors that support its life, are still not well understood. In particular, studies of the distribution and population of Rafflesia on the …


Influence Of Pruning And Organic Fertiliser On 9-Month-Old Ginger Productivity In An Acacia Auriculiformis Agroforestry, Yuda Vatra Erlangga, Arom Figyantika, Cintya Nurul Apsari, Rizki Bagus Indratmoko, Muhammad Syahru Ramadhan, Anastasya Clara Srinila Tampubolon, Fanny Elisabeth Panjaitan May 2026

Influence Of Pruning And Organic Fertiliser On 9-Month-Old Ginger Productivity In An Acacia Auriculiformis Agroforestry, Yuda Vatra Erlangga, Arom Figyantika, Cintya Nurul Apsari, Rizki Bagus Indratmoko, Muhammad Syahru Ramadhan, Anastasya Clara Srinila Tampubolon, Fanny Elisabeth Panjaitan

Jurnal Penelitian Kehutanan Wallacea

Acacia auriculiformis (formis) offers various advantages that can be integrated with agricultural crops like ginger (Zingiber officinale var. amarum) through agroforestry systems. Pruning and fertilisation are potential strategies to optimise this approach. However, existing research remains limited. Further quantification and analysis are required to elucidate the effects of pruning on the growth of 7-year-old formis trees 11 months after treatment. In addition, more comprehensive studies are needed to examine the combined effects of pruning and organic fertiliser on the growth, productivity, and gingerol content of 9-month-old ginger plants. This research employed a Split-Plot Randomised Complete Block Design, examining the …


Species Diversity And Estimation Of Aboveground Carbon Stocks In Sugar Palm Forest And Lowland Forest In Negeri Hatusua, Maluku, Irwanto Irwanto, Andjela Sahupala, Febian Tetelay, Yulianus Komul May 2026

Species Diversity And Estimation Of Aboveground Carbon Stocks In Sugar Palm Forest And Lowland Forest In Negeri Hatusua, Maluku, Irwanto Irwanto, Andjela Sahupala, Febian Tetelay, Yulianus Komul

Jurnal Penelitian Kehutanan Wallacea

Tropical forests are essential for climate change mitigation, but limited data on species diversity and aboveground carbon stocks in Indonesia constrain evidence-based forest management. This study aims to assess species diversity and aboveground carbon stocks in sugar palm forests and lowland forests in Negeri Hatusua, Maluku Province, Indonesia. Vegetation analysis was employed to determine species structure and diversity, while carbon stock measurement and calculation followed the Indonesian National Standard (SNI 7724:2019) for land-based carbon assessment, with certain modifications. The results indicated that the species diversity index in the sugar palm forest was 2.21 for trees, 1.95 for poles, 2.26 for …


Sustainability Of Peatland Area Management With Peat Drainability Assessment At Various Depths, Aulia Bahadhori Mukti, Heru Bagus Pulunggono, Yuli Suharnoto May 2026

Sustainability Of Peatland Area Management With Peat Drainability Assessment At Various Depths, Aulia Bahadhori Mukti, Heru Bagus Pulunggono, Yuli Suharnoto

Jurnal Penelitian Kehutanan Wallacea

This study aims to analyze the distribution of drainability assessment components, including Peat Basal Contact (PBC) and Natural Drainage Limit (NDL) elevations, Drainage Limit Time (DLT), and volume loss, as well as their relationship with peat thickness, subsidence, and groundwater level (GWL) in peatlands. The assessment is conducted to estimate the potential productive lifespan of oil palm plantations by determining the natural drainage limit (NDL) and predicting the time required to reach the drainage threshold, considering subsidence rates across different peat thickness classes. The analysis and calculations were performed using the drainage assessment formulas and procedures outlined by the Roundtable …


Site Characterization And Integrated Irrigation-Forestry Solutions For Mangrove Restoration In The Red River Delta Biosphere Reserve, Vietnam, Manh Quy Do, Huy Quoc Nguyen, Minh Duc Nguyen, My Tra Ha, Tuan Anh Le, Luan Thanh Nguyen, Tu Ngoc Pham May 2026

Site Characterization And Integrated Irrigation-Forestry Solutions For Mangrove Restoration In The Red River Delta Biosphere Reserve, Vietnam, Manh Quy Do, Huy Quoc Nguyen, Minh Duc Nguyen, My Tra Ha, Tuan Anh Le, Luan Thanh Nguyen, Tu Ngoc Pham

Jurnal Penelitian Kehutanan Wallacea

The research was conducted in 2023 in a degraded mangrove forest area in Giao Hoa commune, Ninh Binh province, Vietnam. This area is part of the Red River Delta Biosphere Reserve (RRDBR), which was recognised by UNESCO in 2004. The study employed methods such as surveying topographical features, assessing soil and water characteristics, and evaluating the status of the mangrove forest. It also used GIS and The Analytic Hierarchy Process method to analyse and evaluate the current condition of the forest and its site characteristics. The research results show that, regarding the topographical features of the degraded mangrove area, it …


Urban Bird Community Interaction With Ficus And Non-Ficus Tree, Eka Alifikri, Yeni Aryati Mulyani, Ani Mardiastuti May 2026

Urban Bird Community Interaction With Ficus And Non-Ficus Tree, Eka Alifikri, Yeni Aryati Mulyani, Ani Mardiastuti

Jurnal Penelitian Kehutanan Wallacea

Ficus trees are recognised as keystone species in forest ecosystems and are crucial for urban wildlife, especially birds. IPB Darmaga Campus, a biodiversity-rich urban area, hosts a variety of plant species, including Ficus and non-Ficus tree species, along with diverse bird species. This study aimed to compare the utilisation of Ficus and non-Ficus plants by birds in the area. Observations were conducted on 5 Ficus benjamina, 5 Ficus microcarpa, and 10 non-Ficus tree individuals. Ficus trees were used by 15 bird species from 12 families, with 1700 recorded interactions. In contrast, non-Ficus trees were …


Addressing Socioeconomic Factors Related To Health Disparities In Predominantly Hispanic Texas Communities, Gabriela M. Gomez May 2026

Addressing Socioeconomic Factors Related To Health Disparities In Predominantly Hispanic Texas Communities, Gabriela M. Gomez

Theses & Dissertations

This qualitative study examined the socioeconomic factors that influenced health outcomes in predominantly Hispanic Texas communities in San Antonio, Texas. Few studies have been conducted that address how socioeconomic conditions have shaped the lives of the Hispanic population in Texas, indicating a significant gap in the research. The research question guiding this study asked: How do Hispanic individuals between the ages of 26 and 64 who live in predominantly Hispanic communities describe health disparities in San Antonio, Texas? To address the research question, a qualitative inquiry was conducted using semi-structured in-person interviews with participants who met the inclusion criteria. A …


Exploring The Transformative Effects Of Executive Coaching On Leaders: A Qualitative Study, Dwayne Norman May 2026

Exploring The Transformative Effects Of Executive Coaching On Leaders: A Qualitative Study, Dwayne Norman

Theses & Dissertations

This qualitative dissertation examines the transformative effects of executive coaching on leaders’ development, personal growth, decision-making, and overall effectiveness across varied organizational contexts. Grounded in authentic leadership theory and employing a generic qualitative inquiry design, the study investigated how leaders who completed executive coaching describe changes in their behavior and mindset. Eleven experienced leaders participated in semi-structured interviews selected through purposive sampling. Thematic analysis, guided by the cyclical and inductive coding methods of Saldana (2021), generated 187 initial codes, which were distilled into 72 final codes. These final codes were then further refined into twelve categories and four overarching themes: …


A Case Study Of Doctoral Students' Perspectives Of The Drastic Move From An In-Person To Virtual Environment During Covid-19, Martha Patricia Cias May 2026

A Case Study Of Doctoral Students' Perspectives Of The Drastic Move From An In-Person To Virtual Environment During Covid-19, Martha Patricia Cias

Theses & Dissertations

This qualitative case research study investigated the students’ perspectives during the drastic transition from an in-person to a virtual environment during the COVID-19 pandemic (2020-2021) at the doctoral level. The findings were grouped into six themes and revealed (a) the loss of structure and increased isolation, (b) development of online literacy and increased flexibility, (c) social movements stress and peer/professor support, (d) emotional resilience and resource use, (e) recognition of hybrid and mentorship models, and (f) the need for institutional preparedness considering students as stakeholders/customers. Concluding with the acknowledgement of the capacity of doctoral students to adapt in an unforeseen …


The Faculty's Perception Of The Role Of Equity In The Formation Of Cooperative Learning Groups In University Classrooms: A Qualitative Inquiry, Ethel Nwogu May 2026

The Faculty's Perception Of The Role Of Equity In The Formation Of Cooperative Learning Groups In University Classrooms: A Qualitative Inquiry, Ethel Nwogu

Theses & Dissertations

THE FACULTY’S PERCEPTION OF THE ROLE OF EQUITY IN THE FORMATION OF COOPERATIVE LEARNING GROUPS IN UNIVERSITY CLASSROOMS: A QUALITATIVE INQUIRY

Submitted by Ethel K. Nwogu A Dissertation Presented in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of the Incarnate Word San Antonio, Texas December 2025

This study investigates how university faculty perceive and apply equity in the formation of cooperative learning groups. It examines the beliefs guiding instructional decisions and the practical strategies used to ensure fairness and inclusion. The central purpose is to understand how equitable group formation practices influence student …


Library News May 2026, Research Medical Library May 2026

2026 Spring Commencement, Tennessee State University May 2026

2026 Spring Commencement, Tennessee State University

TSU Commencements 2025-Present – Mr. Dwayne Tucker, President

No abstract provided.


Processing Conditions In Narrative Interpretation: A Structural Account Of Cf/Ef Divergence In "The Clerk's Tale”, Griselda Poe May 2026

Processing Conditions In Narrative Interpretation: A Structural Account Of Cf/Ef Divergence In "The Clerk's Tale”, Griselda Poe

Publications and Research

This paper applies the framework established in Paper 19, "Cognition Is Not Content: A Structural Account of Processing Conditions," to re-describe Chaucer's "The Clerk's Tale" from The Canterbury Tales.

The same narrative produces two incompatible interpretations: a record of domestic violence, and a story of genuine love. This divergence does not arise from differences in ethical judgment or emotional response. It arises from structural differences in the conditions under which information is reconstructed.

This paper does three things. First, it analyzes the characters Walter and Griselda in terms of CF (Core-foregrounded) and EF (Modulation-foregrounded) processing conditions. Second, it describes …


Comparing Two Emergent Literacy Screeners: The Reading House And Star Early Literacy In A Florida Voluntary Pre-Kindergarten (Vpk) Program, Jaime D. Swenbeck May 2026

Comparing Two Emergent Literacy Screeners: The Reading House And Star Early Literacy In A Florida Voluntary Pre-Kindergarten (Vpk) Program, Jaime D. Swenbeck

Poster Presentations

Emergent Literacy (EL) refers to the foundational skills that develop from birth through the preschool years and support later reading success (National Early Literacy Panel, 2008; Levy et al., 2006). These include basic Print Concepts, Phonological Awareness, Vocabulary, Letter-Sound Knowledge, and Emergent Writing (Piasta et al., 2021; Puranik et al., 2011). Because they serve as predictors for later literacy success, accurate identification of children struggling to learn EL skills is important. There are various types of tools, ranging from screening tools to diagnostic assessments, that measure children’s EL skills, with assessment times ranging from 10-15 minutes to 45-60 minutes. In …


Where Springs Not Fail, Hannah Guo May 2026

Where Springs Not Fail, Hannah Guo

Graduate Thesis Collection

Where Springs Not Fail is a 23-minute multimovement work for mixed choir, mezzo-soprano and baritone soloists, and a chamber instrumental ensemble. Drawing texts from Gerard Manley Hopkins and Rabindranath Tagore, the composition explores themes of spiritual darkness, anxiety, and a profound yearning for hope—shared human experiences that are often under-acknowledged. The work aims to reside between sacred and secular expressions, offering a space of vulnerability, reflection, and honesty for performers and listeners alike.

The composition engages a wide range of stylistic influences, including serial and minimalist techniques, chant-like melodic writing, modal language, and motivic symbolism. Structured as an arch form, …


Moral Injury Among Healthcare Chaplains: Responding To Systemic Racism Through Ethical Advocacy And Spiritual Care, Stephanie Drew May 2026

Moral Injury Among Healthcare Chaplains: Responding To Systemic Racism Through Ethical Advocacy And Spiritual Care, Stephanie Drew

Doctor of Ministry Projects and Theses

Systemic racism against minorities has woven its way into every facet of everyday existence, especially for Black Americans, and Healthcare is no exception. There are numerous proven instances of unfair and inequitable treatment of marginalized patients throughout the Healthcare system, and some have even caused Black patients to lose their lives. The mistreatment of Black and Brown people during perhaps one of the most vulnerable times of their lives is well documented dating back centuries. There are massive cuts to Medicaid, and insurance premiums are steadily going up making it very cumbersome for the poor and disenfranchised to navigate the …


Effect Of Obsessive Thoughts On The Stigma Of Obsessive-Compulsive Disorder: Thoughts Of Harm And Sex About Oneself Or Other People, Emma L. Podvorec May 2026

Effect Of Obsessive Thoughts On The Stigma Of Obsessive-Compulsive Disorder: Thoughts Of Harm And Sex About Oneself Or Other People, Emma L. Podvorec

Undergraduate Honors Thesis Collection

This study investigated how obsession content (sexual vs. violent) and target (self vs. others) influence OCD stigma. Using a 3×3 factorial design, 152 participants read vignettes describing an individual experiencing either sexual or violent obsessions directed at either themself or other people, or a control condition describing an individual not experiencing obsessions at all. Participants then rated their desired social distance – a measure of stigma – from the individual described in the vignette. After controlling for participants' own OCD symptoms, a significant main effect for obsession content (p < .001, ηp2 = .14) emerged. Both sexual and violent obsessions elicited significantly higher stigma than the control, though the experimental conditions did not differ from each other. Conversely, the obsession target and the interaction between content and target were non-significant (p’s>.05). These results suggest that the "taboo" nature of an obsession …


A New Generation Of Inhaled Vaccines, Clark Chapman May 2026

A New Generation Of Inhaled Vaccines, Clark Chapman

Undergraduate Honors Thesis Collection

Vaccines have stood the test of time as being one of the greatest developments in health history. Delivery of these life-saving vaccines has primarily remained reliant on intramuscular administration, which has its own collection of shortcomings. When considering what vaccine formulation is best suited to be a widely accessible and effective tool in the fight against respiratory pathogens, current data and science points to a number of improvements available to us. These improvements include:

• An inhaled formulation, uniquely stimulating mucosal immunity

• A dry powder formulation to improve long-term stability

• A live attenuated vaccine to increase immunogenic response …


The Role And Impact Of Servant Leaders In The Clinical Physical Therapy Space, Amelia Moor May 2026

The Role And Impact Of Servant Leaders In The Clinical Physical Therapy Space, Amelia Moor

Undergraduate Honors Thesis Collection

Servant leadership is an approach that is committed to improving the lives of others. The patient-centered model, commonly taught in healthcare courses, follows a structure that resembles the practice of servant leadership. Through this study, the clinical application of servant leadership was explored further. Physical therapy was the primary focus of understanding servant leadership in healthcare settings. Qualitative research was conducted using a phronetic iterative approach. Results displayed a recognition and usage of the servant leadership model in physical therapy settings, despite administrative and structural barriers.


Curriculum Evaluation For Imagiedu, Madison Leigh Marchand May 2026

Curriculum Evaluation For Imagiedu, Madison Leigh Marchand

Undergraduate Honors Thesis Collection

This research examines whether or not ImagiEdu's curriculum aligns with the Indiana Academic Standards for K-8 Computer Science, and to determine if it meets the requirements to be approved as "High-Quality Curricular Materials" by the Indiana Department of Education (DOE). ImagiEdu is an award-winning technology education startup from Sweden, and provides inclusive coding education tools designed to help students imagine their future in the tech world. In this project, the DOE's 2024-2025 High-Quality Curricular Materials Rubric was used to evaluate ImagiEdu's curriculum, including its Scope and Sequence, Teacher Handbook, and over 25 Lesson Plans. The evaluation focused on four main …


Partners In Crime: Unraveling Accomplice Involvement In Jury Verdicts, Daphne A. Murray May 2026

Partners In Crime: Unraveling Accomplice Involvement In Jury Verdicts, Daphne A. Murray

Undergraduate Honors Thesis Collection

The present study is only the second investigation to examine the effects of accomplice witness testimony on jury decision making. For this study, participants read a trial transcript of an assault case in which the defendant was accused of starting a physical altercation. Participants were randomly assigned to one of three conditions where we varied the level of involvement of the accomplice. The three conditions included Accomplice-Altercation where the accomplice was directly involved in the altercation and threw a few punches, Accomplice-Lookout where the accomplice served as a lookout for police arrival, and a No Accomplice condition. The results of …


Illuminating Success: Student And Teacher Perception On Media Center Brainlit Lighting, Jase M. H. Ide May 2026

Illuminating Success: Student And Teacher Perception On Media Center Brainlit Lighting, Jase M. H. Ide

Undergraduate Honors Thesis Collection

Lighting plays a critical role in shaping learning environments, yet its influence on students’ cognitive, emotional, and physiological functioning is often overlooked in educational research. This study examined the perceived impact of BrainLit’s biocentric lighting, a daylight-simulating system designed to support circadian rhythms, within an educational setting. The research focused on Sycamore School, the first early childhood through eighth-grade school in the United States to implement BrainLit biocentric lighting. Using a qualitative research design, data were collected through interviews with third- and eighth-grade students and faculty members in the school’s Media Center. Transcribed interviews were analyzed thematically to identify patterns …


Group B Streptococcus In Pregnant Women: Universal Guidelines And Protocols, Dania Presteguin May 2026

Group B Streptococcus In Pregnant Women: Universal Guidelines And Protocols, Dania Presteguin

Undergraduate Honors Thesis Collection

Background: Group B Streptococcus (GBS) is a leading cause of maternal sepsis and neonatal mortality globally. Variability in screening and treatment guidelines influences global disease burden.

Objective: This study uses a cross-national analysis to compare screening and treatment guidelines and their impact on prevalence, screening, intrapartum antibiotic prophylaxis (IAP), and maternal-neonatal clinical manifestations Methodology: A systematic review of secondary literature was conducted using PubMed, Scopus, and CINAHL (2010-2025). Inclusion criteria include maternal GBS colonization and one or more measures of interventions and neonatal infection rates. No geographic or demographic restrictions were applied. A total of 67 studies were screened, and …


Cyanine Dyes As Next-Generation Fluorophores: Applications In Cell Sorting And Fingerprinting Technologies, Super-Multiplexed Spectroscopy, Biomedical Imaging, And Beyond, Lucas Allen Davis May 2026

Cyanine Dyes As Next-Generation Fluorophores: Applications In Cell Sorting And Fingerprinting Technologies, Super-Multiplexed Spectroscopy, Biomedical Imaging, And Beyond, Lucas Allen Davis

Undergraduate Honors Thesis Collection

As biochemical, pharmaceutical, and medical sciences advance, the demand for technologies capable of probing multiple cellular targets simultaneously continues to increase. Super-multiplexed spectroscopic techniques offer a pathway toward comprehensive cellular fingerprinting by overcoming the spectral limitations of conventional fluorescence labeling. By circumventing the traditional “color barrier,” cyanine-based Raman tags enable the simultaneous discrimination of numerous cellular morphologies, allowing spectroscopy and imaging to be integrated for high-dimensional cellular analysis. Technologies developed in Goda Lab—including high-throughput flow cytometry, virtual freezing fluorescence imaging (VIFFI), Fourier-transform coherent anti-Stokes Raman spectroscopy (FT-CARS), and MERdot nanoparticles—address longstanding trade-offs between throughput, resolution, sensitivity, and multiplexing capacity. Central …